Stem definition | Drug id | CAS RN |
---|---|---|
2302 | 2078-54-8 |
None
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 2 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 0.16 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 0.50 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 14.02 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
Vd (Volume of distribution) | 4.70 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 36 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.02 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 3.20 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
Oct. 2, 1989 | FDA | FRESENIUS KABI USA |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Anaphylactic shock | 2370.95 | 15.32 | 782 | 35070 | 19373 | 50549899 |
Anaphylactic reaction | 1025.03 | 15.32 | 575 | 35277 | 53480 | 50515792 |
Hypotension | 757.43 | 15.32 | 880 | 34972 | 234589 | 50334683 |
Bronchospasm | 736.96 | 15.32 | 306 | 35546 | 14548 | 50554724 |
Cardiac arrest | 715.67 | 15.32 | 540 | 35312 | 83111 | 50486161 |
Propofol infusion syndrome | 688.51 | 15.32 | 149 | 35703 | 617 | 50568655 |
Circulatory collapse | 387.17 | 15.32 | 216 | 35636 | 19784 | 50549488 |
Serotonin syndrome | 377.90 | 15.32 | 229 | 35623 | 24484 | 50544788 |
Delayed recovery from anaesthesia | 372.66 | 15.32 | 90 | 35762 | 659 | 50568613 |
Tachycardia | 369.02 | 15.32 | 402 | 35450 | 99361 | 50469911 |
Stress cardiomyopathy | 339.54 | 15.32 | 147 | 35705 | 7740 | 50561532 |
Bradycardia | 313.32 | 15.32 | 301 | 35551 | 64125 | 50505147 |
Hyperthermia malignant | 307.91 | 15.32 | 77 | 35775 | 662 | 50568610 |
Respiratory depression | 274.94 | 15.32 | 145 | 35707 | 11865 | 50557407 |
Fatigue | 271.51 | 15.32 | 83 | 35769 | 707518 | 49861754 |
Status epilepticus | 257.25 | 15.32 | 144 | 35708 | 13262 | 50556010 |
Ventricular tachycardia | 242.81 | 15.32 | 147 | 35705 | 15674 | 50553598 |
Drug interaction | 238.61 | 15.32 | 471 | 35381 | 199150 | 50370122 |
Neuromuscular block prolonged | 231.78 | 15.32 | 57 | 35795 | 454 | 50568818 |
Arthralgia | 229.08 | 15.32 | 23 | 35829 | 438679 | 50130593 |
Multiple organ dysfunction syndrome | 212.80 | 15.32 | 218 | 35634 | 50119 | 50519153 |
Ventricular fibrillation | 212.38 | 15.32 | 117 | 35735 | 10442 | 50558830 |
Shock | 200.16 | 15.32 | 144 | 35708 | 20506 | 50548766 |
Oxygen saturation decreased | 193.93 | 15.32 | 249 | 35603 | 72999 | 50496273 |
Diarrhoea | 193.55 | 15.32 | 88 | 35764 | 588388 | 49980884 |
Metabolic acidosis | 185.97 | 15.32 | 180 | 35672 | 38645 | 50530627 |
Blood pressure decreased | 185.34 | 15.32 | 213 | 35639 | 55696 | 50513576 |
Haemodynamic instability | 172.71 | 15.32 | 93 | 35759 | 7931 | 50561341 |
Procedural hypotension | 167.15 | 15.32 | 52 | 35800 | 1050 | 50568222 |
Pulseless electrical activity | 163.41 | 15.32 | 85 | 35767 | 6756 | 50562516 |
Apnoea | 161.96 | 15.32 | 85 | 35767 | 6881 | 50562391 |
Anaesthetic complication | 159.29 | 15.32 | 56 | 35796 | 1674 | 50567598 |
Joint swelling | 155.09 | 15.32 | 4 | 35848 | 245282 | 50323990 |
Unwanted awareness during anaesthesia | 150.82 | 15.32 | 36 | 35816 | 249 | 50569023 |
Dystonia | 148.30 | 15.32 | 97 | 35755 | 11829 | 50557443 |
Fall | 143.79 | 15.32 | 31 | 35821 | 334901 | 50234371 |
Myoclonus | 142.72 | 15.32 | 102 | 35750 | 14368 | 50554904 |
Diabetes insipidus | 138.75 | 15.32 | 55 | 35797 | 2309 | 50566963 |
Alopecia | 138.35 | 15.32 | 9 | 35843 | 245038 | 50324234 |
Anaphylactoid shock | 136.81 | 15.32 | 34 | 35818 | 284 | 50568988 |
Drug intolerance | 133.37 | 15.32 | 5 | 35847 | 219099 | 50350173 |
Rhabdomyolysis | 133.21 | 15.32 | 151 | 35701 | 38876 | 50530396 |
Hypoxia | 130.88 | 15.32 | 171 | 35681 | 50952 | 50518320 |
Post procedural complication | 127.63 | 15.32 | 97 | 35755 | 15007 | 50554265 |
Labile blood pressure | 127.54 | 15.32 | 47 | 35805 | 1613 | 50567659 |
Generalised tonic-clonic seizure | 120.39 | 15.32 | 119 | 35733 | 26191 | 50543081 |
Airway complication of anaesthesia | 118.68 | 15.32 | 28 | 35824 | 183 | 50569089 |
Headache | 118.48 | 15.32 | 111 | 35741 | 506424 | 50062848 |
Procedural complication | 118.27 | 15.32 | 61 | 35791 | 4762 | 50564510 |
Electrocardiogram ST segment elevation | 115.28 | 15.32 | 54 | 35798 | 3419 | 50565853 |
Abdominal discomfort | 113.53 | 15.32 | 15 | 35837 | 231626 | 50337646 |
Blood creatine phosphokinase increased | 112.82 | 15.32 | 115 | 35737 | 26252 | 50543020 |
Nasopharyngitis | 112.17 | 15.32 | 6 | 35846 | 192921 | 50376351 |
Rheumatoid arthritis | 109.83 | 15.32 | 9 | 35843 | 202541 | 50366731 |
Laryngospasm | 108.83 | 15.32 | 48 | 35804 | 2640 | 50566632 |
Respiratory acidosis | 108.19 | 15.32 | 62 | 35790 | 5966 | 50563306 |
Pain | 107.20 | 15.32 | 153 | 35699 | 578750 | 49990522 |
Anaphylactoid reaction | 104.00 | 15.32 | 50 | 35802 | 3356 | 50565916 |
Cardio-respiratory arrest | 103.36 | 15.32 | 157 | 35695 | 53735 | 50515537 |
Myoglobin urine present | 101.60 | 15.32 | 28 | 35824 | 362 | 50568910 |
Hypoventilation | 100.23 | 15.32 | 51 | 35801 | 3870 | 50565402 |
Torsade de pointes | 99.98 | 15.32 | 76 | 35776 | 11759 | 50557513 |
Malaise | 99.77 | 15.32 | 57 | 35795 | 335475 | 50233797 |
Pain in extremity | 98.85 | 15.32 | 35 | 35817 | 272830 | 50296442 |
Cardiogenic shock | 95.48 | 15.32 | 83 | 35769 | 15516 | 50553756 |
Unresponsive to stimuli | 95.34 | 15.32 | 113 | 35739 | 30496 | 50538776 |
Product dose omission issue | 94.78 | 15.32 | 10 | 35842 | 183828 | 50385444 |
Sinusitis | 94.08 | 15.32 | 7 | 35845 | 170551 | 50398721 |
Peripheral swelling | 92.59 | 15.32 | 17 | 35835 | 205919 | 50363353 |
Respiratory failure | 92.02 | 15.32 | 201 | 35651 | 90980 | 50478292 |
Clonus | 91.55 | 15.32 | 49 | 35803 | 4126 | 50565146 |
Type I hypersensitivity | 91.46 | 15.32 | 41 | 35811 | 2344 | 50566928 |
Tryptase increased | 91.42 | 15.32 | 23 | 35829 | 203 | 50569069 |
Arthropathy | 88.47 | 15.32 | 6 | 35846 | 157900 | 50411372 |
Nausea | 86.91 | 15.32 | 237 | 35615 | 705161 | 49864111 |
Arteriospasm coronary | 86.23 | 15.32 | 44 | 35808 | 3358 | 50565914 |
Anticholinergic syndrome | 85.64 | 15.32 | 36 | 35816 | 1759 | 50567513 |
Dizziness | 85.53 | 15.32 | 72 | 35780 | 346297 | 50222975 |
Weight increased | 83.90 | 15.32 | 20 | 35832 | 201871 | 50367401 |
PCO2 increased | 82.82 | 15.32 | 31 | 35821 | 1112 | 50568160 |
Product contamination | 82.70 | 15.32 | 26 | 35826 | 544 | 50568728 |
Mydriasis | 82.69 | 15.32 | 65 | 35787 | 10562 | 50558710 |
Anaesthetic complication pulmonary | 81.85 | 15.32 | 16 | 35836 | 34 | 50569238 |
Systemic lupus erythematosus | 79.79 | 15.32 | 5 | 35847 | 140617 | 50428655 |
Respiratory arrest | 79.30 | 15.32 | 102 | 35750 | 29907 | 50539365 |
Intestinal ischaemia | 79.25 | 15.32 | 53 | 35799 | 6704 | 50562568 |
Opisthotonus | 78.28 | 15.32 | 22 | 35830 | 307 | 50568965 |
Renal ischaemia | 78.04 | 15.32 | 25 | 35827 | 557 | 50568715 |
Weight decreased | 77.37 | 15.32 | 30 | 35822 | 221215 | 50348057 |
Ventricular hypokinesia | 77.00 | 15.32 | 43 | 35809 | 3937 | 50565335 |
Transmission of an infectious agent via product | 75.22 | 15.32 | 18 | 35834 | 126 | 50569146 |
Oliguria | 74.38 | 15.32 | 55 | 35797 | 8161 | 50561111 |
Dyspnoea | 73.48 | 15.32 | 176 | 35676 | 547432 | 50021840 |
Intra-abdominal pressure increased | 72.51 | 15.32 | 19 | 35833 | 200 | 50569072 |
Swelling | 72.30 | 15.32 | 26 | 35826 | 200846 | 50368426 |
Infusion related reaction | 72.02 | 15.32 | 16 | 35836 | 169541 | 50399731 |
Disseminated intravascular coagulation | 70.15 | 15.32 | 73 | 35779 | 17062 | 50552210 |
Encephalopathy | 70.05 | 15.32 | 102 | 35750 | 33609 | 50535663 |
Mitochondrial DNA mutation | 70.01 | 15.32 | 19 | 35833 | 231 | 50569041 |
Laryngeal oedema | 69.99 | 15.32 | 44 | 35808 | 5009 | 50564263 |
Hepatic ischaemia | 69.04 | 15.32 | 23 | 35829 | 582 | 50568690 |
Pulmonary oedema | 68.81 | 15.32 | 124 | 35728 | 48814 | 50520458 |
Contraindicated product administered | 67.57 | 15.32 | 12 | 35840 | 148946 | 50420326 |
Insomnia | 67.56 | 15.32 | 20 | 35832 | 174845 | 50394427 |
Multiple-drug resistance | 67.39 | 15.32 | 37 | 35815 | 3277 | 50565995 |
Exposure during pregnancy | 66.80 | 15.32 | 213 | 35639 | 120802 | 50448470 |
Pruritus | 66.28 | 15.32 | 62 | 35790 | 283506 | 50285766 |
Brain oedema | 66.16 | 15.32 | 61 | 35791 | 12309 | 50556963 |
Stridor | 66.15 | 15.32 | 36 | 35816 | 3133 | 50566139 |
Vasoplegia syndrome | 65.66 | 15.32 | 26 | 35826 | 1088 | 50568184 |
Pneumatosis | 63.95 | 15.32 | 20 | 35832 | 411 | 50568861 |
Blood gases abnormal | 63.90 | 15.32 | 22 | 35830 | 617 | 50568655 |
PO2 increased | 62.14 | 15.32 | 23 | 35829 | 799 | 50568473 |
Constipation | 61.96 | 15.32 | 27 | 35825 | 185681 | 50383591 |
Seizure | 61.02 | 15.32 | 203 | 35649 | 117671 | 50451601 |
Acute respiratory distress syndrome | 60.97 | 15.32 | 75 | 35777 | 21024 | 50548248 |
Drug ineffective for unapproved indication | 60.45 | 15.32 | 75 | 35777 | 21206 | 50548066 |
Blood pH decreased | 60.05 | 15.32 | 31 | 35821 | 2424 | 50566848 |
Electrocardiogram QT prolonged | 60.02 | 15.32 | 121 | 35731 | 51765 | 50517507 |
Agitation | 59.98 | 15.32 | 123 | 35729 | 53261 | 50516011 |
Hyperreflexia | 59.68 | 15.32 | 40 | 35812 | 5078 | 50564194 |
Oculogyric crisis | 59.27 | 15.32 | 26 | 35826 | 1411 | 50567861 |
Premature delivery | 58.74 | 15.32 | 78 | 35774 | 23585 | 50545687 |
Decreased appetite | 58.41 | 15.32 | 35 | 35817 | 200888 | 50368384 |
Neuromuscular blockade | 58.28 | 15.32 | 17 | 35835 | 273 | 50568999 |
Hepatorenal syndrome | 57.54 | 15.32 | 27 | 35825 | 1716 | 50567556 |
Amylase increased | 57.53 | 15.32 | 40 | 35812 | 5390 | 50563882 |
Dyskinesia | 57.45 | 15.32 | 84 | 35768 | 27777 | 50541495 |
Coagulopathy | 57.11 | 15.32 | 67 | 35785 | 17877 | 50551395 |
Erythema | 57.10 | 15.32 | 230 | 35622 | 146184 | 50423088 |
Endotracheal intubation complication | 56.88 | 15.32 | 18 | 35834 | 385 | 50568887 |
Septic shock | 56.46 | 15.32 | 125 | 35727 | 57050 | 50512222 |
Anaesthetic complication neurological | 56.32 | 15.32 | 15 | 35837 | 169 | 50569103 |
Sinus tachycardia | 55.50 | 15.32 | 72 | 35780 | 21282 | 50547990 |
Lower respiratory tract infection | 55.17 | 15.32 | 3 | 35849 | 95198 | 50474074 |
End-tidal CO2 decreased | 54.66 | 15.32 | 10 | 35842 | 12 | 50569260 |
Oxygen saturation abnormal | 54.48 | 15.32 | 30 | 35822 | 2672 | 50566600 |
Muscle rigidity | 53.59 | 15.32 | 49 | 35803 | 9780 | 50559492 |
Electrocardiogram QRS complex prolonged | 53.44 | 15.32 | 38 | 35814 | 5306 | 50563966 |
Contusion | 53.18 | 15.32 | 8 | 35844 | 112175 | 50457097 |
Discomfort | 53.09 | 15.32 | 7 | 35845 | 108373 | 50460899 |
Renal impairment | 53.01 | 15.32 | 145 | 35707 | 75516 | 50493756 |
Carcinoid crisis | 52.94 | 15.32 | 15 | 35837 | 216 | 50569056 |
Musculoskeletal stiffness | 52.81 | 15.32 | 13 | 35839 | 128468 | 50440804 |
Bronchitis | 52.80 | 15.32 | 6 | 35846 | 104153 | 50465119 |
Ventricular extrasystoles | 52.66 | 15.32 | 50 | 35802 | 10466 | 50558806 |
Atrioventricular block complete | 51.39 | 15.32 | 42 | 35810 | 7213 | 50562059 |
Foetal death | 51.01 | 15.32 | 44 | 35808 | 8136 | 50561136 |
Postoperative delirium | 50.92 | 15.32 | 12 | 35840 | 78 | 50569194 |
Upper airway obstruction | 50.66 | 15.32 | 18 | 35834 | 555 | 50568717 |
Hepatocellular injury | 50.30 | 15.32 | 76 | 35776 | 25871 | 50543401 |
Toxic encephalopathy | 50.10 | 15.32 | 37 | 35815 | 5478 | 50563794 |
Arthritis | 49.43 | 15.32 | 3 | 35849 | 86718 | 50482554 |
Wound | 49.12 | 15.32 | 8 | 35844 | 105786 | 50463486 |
Therapeutic product effect prolonged | 48.44 | 15.32 | 15 | 35837 | 298 | 50568974 |
Influenza | 48.43 | 15.32 | 4 | 35848 | 89534 | 50479738 |
Necrosis ischaemic | 48.33 | 15.32 | 19 | 35833 | 780 | 50568492 |
Acute generalised exanthematous pustulosis | 47.65 | 15.32 | 44 | 35808 | 8894 | 50560378 |
Acute pulmonary oedema | 47.17 | 15.32 | 40 | 35812 | 7227 | 50562045 |
Post procedural haemorrhage | 47.16 | 15.32 | 40 | 35812 | 7230 | 50562042 |
Gastrointestinal disorder | 46.50 | 15.32 | 6 | 35846 | 94450 | 50474822 |
Stomatitis | 46.30 | 15.32 | 8 | 35844 | 101336 | 50467936 |
Shock haemorrhagic | 46.28 | 15.32 | 42 | 35810 | 8302 | 50560970 |
Gene mutation | 46.04 | 15.32 | 21 | 35831 | 1250 | 50568022 |
Pneumonia | 45.73 | 15.32 | 128 | 35724 | 378273 | 50190999 |
Unmasking of previously unidentified disease | 45.30 | 15.32 | 18 | 35834 | 760 | 50568512 |
Death | 44.77 | 15.32 | 103 | 35749 | 325276 | 50243996 |
Posterior reversible encephalopathy syndrome | 44.64 | 15.32 | 54 | 35798 | 14874 | 50554398 |
Urinary tract infection | 44.52 | 15.32 | 56 | 35796 | 223964 | 50345308 |
Acute hepatic failure | 44.12 | 15.32 | 55 | 35797 | 15622 | 50553650 |
Fear | 44.12 | 15.32 | 53 | 35799 | 14496 | 50554776 |
Gait disturbance | 43.76 | 15.32 | 26 | 35826 | 149979 | 50419293 |
Angioedema | 43.73 | 15.32 | 88 | 35764 | 37588 | 50531684 |
Hypovolaemia | 43.63 | 15.32 | 43 | 35809 | 9422 | 50559850 |
Muscle relaxant therapy | 42.93 | 15.32 | 12 | 35840 | 164 | 50569108 |
Back pain | 42.69 | 15.32 | 56 | 35796 | 219974 | 50349298 |
Mental status changes postoperative | 42.47 | 15.32 | 12 | 35840 | 171 | 50569101 |
Cardiovascular insufficiency | 42.20 | 15.32 | 20 | 35832 | 1300 | 50567972 |
Perforation | 41.58 | 15.32 | 18 | 35834 | 946 | 50568326 |
Troponin increased | 41.42 | 15.32 | 39 | 35813 | 8079 | 50561193 |
Confusion postoperative | 41.24 | 15.32 | 12 | 35840 | 191 | 50569081 |
Suspected product quality issue | 41.12 | 15.32 | 12 | 35840 | 193 | 50569079 |
Blood bicarbonate decreased | 40.97 | 15.32 | 25 | 35827 | 2700 | 50566572 |
Blood lactic acid increased | 40.96 | 15.32 | 33 | 35819 | 5552 | 50563720 |
Pulse absent | 40.89 | 15.32 | 31 | 35821 | 4775 | 50564497 |
Product contamination microbial | 40.83 | 15.32 | 12 | 35840 | 198 | 50569074 |
Hepatic failure | 40.61 | 15.32 | 78 | 35774 | 32205 | 50537067 |
Renal failure | 40.34 | 15.32 | 166 | 35686 | 106467 | 50462805 |
Asthenia | 39.97 | 15.32 | 106 | 35746 | 318936 | 50250336 |
Coma | 39.83 | 15.32 | 109 | 35743 | 56770 | 50512502 |
Chest pain | 39.74 | 15.32 | 40 | 35812 | 176842 | 50392430 |
Hypercapnia | 39.71 | 15.32 | 30 | 35822 | 4597 | 50564675 |
Procedural nausea | 39.60 | 15.32 | 16 | 35836 | 706 | 50568566 |
Alanine aminotransferase increased | 39.49 | 15.32 | 145 | 35707 | 88214 | 50481058 |
Electrocardiogram ST segment depression | 39.29 | 15.32 | 24 | 35828 | 2596 | 50566676 |
Acidosis hyperchloraemic | 39.17 | 15.32 | 13 | 35839 | 325 | 50568947 |
Injection site pain | 38.86 | 15.32 | 15 | 35837 | 111009 | 50458263 |
Hepatorenal failure | 38.81 | 15.32 | 15 | 35837 | 588 | 50568684 |
Local anaesthetic systemic toxicity | 38.59 | 15.32 | 15 | 35837 | 597 | 50568675 |
Hyperlactacidaemia | 38.32 | 15.32 | 23 | 35829 | 2410 | 50566862 |
Hepatitis acute | 38.25 | 15.32 | 37 | 35815 | 7924 | 50561348 |
Skin test positive | 37.60 | 15.32 | 15 | 35837 | 640 | 50568632 |
Neuropathy peripheral | 37.47 | 15.32 | 11 | 35841 | 96746 | 50472526 |
Neutropenia | 37.37 | 15.32 | 30 | 35822 | 147935 | 50421337 |
Airway peak pressure increased | 36.82 | 15.32 | 12 | 35840 | 283 | 50568989 |
Inappropriate schedule of product administration | 36.75 | 15.32 | 4 | 35848 | 71827 | 50497445 |
Cardiac output decreased | 36.20 | 15.32 | 16 | 35836 | 884 | 50568388 |
Delirium | 36.02 | 15.32 | 82 | 35770 | 38110 | 50531162 |
Wrong product administered | 35.81 | 15.32 | 30 | 35822 | 5330 | 50563942 |
Renal injury | 35.81 | 15.32 | 37 | 35815 | 8574 | 50560698 |
Subcutaneous emphysema | 35.51 | 15.32 | 15 | 35837 | 742 | 50568530 |
Altered state of consciousness | 35.33 | 15.32 | 59 | 35793 | 21851 | 50547421 |
Electroencephalogram abnormal | 35.26 | 15.32 | 25 | 35827 | 3474 | 50565798 |
Procedural vomiting | 35.08 | 15.32 | 13 | 35839 | 453 | 50568819 |
Ultrasound ovary abnormal | 35.04 | 15.32 | 9 | 35843 | 87 | 50569185 |
Psoriasis | 34.90 | 15.32 | 4 | 35848 | 68996 | 50500276 |
Left ventricle outflow tract obstruction | 34.86 | 15.32 | 11 | 35841 | 233 | 50569039 |
Hypocapnia | 34.84 | 15.32 | 12 | 35840 | 337 | 50568935 |
Laryngeal stenosis | 34.76 | 15.32 | 15 | 35837 | 782 | 50568490 |
Abdominal pain upper | 34.68 | 15.32 | 37 | 35815 | 159272 | 50410000 |
Infection | 34.59 | 15.32 | 43 | 35809 | 172911 | 50396361 |
Coma scale abnormal | 34.59 | 15.32 | 28 | 35824 | 4743 | 50564529 |
Macroglossia | 34.52 | 15.32 | 14 | 35838 | 624 | 50568648 |
Maternal exposure during delivery | 34.50 | 15.32 | 16 | 35836 | 990 | 50568282 |
Atrioventricular block second degree | 34.49 | 15.32 | 25 | 35827 | 3596 | 50565676 |
Toxic epidermal necrolysis | 34.48 | 15.32 | 57 | 35795 | 20935 | 50548337 |
Arrhythmia | 34.48 | 15.32 | 74 | 35778 | 33058 | 50536214 |
Malignant neoplasm progression | 34.33 | 15.32 | 4 | 35848 | 68120 | 50501152 |
Oedema peripheral | 34.04 | 15.32 | 37 | 35815 | 157924 | 50411348 |
Atrioventricular block first degree | 33.98 | 15.32 | 31 | 35821 | 6170 | 50563102 |
Paralysis | 33.83 | 15.32 | 36 | 35816 | 8628 | 50560644 |
Oropharyngeal pain | 33.71 | 15.32 | 7 | 35845 | 77794 | 50491478 |
Herpes zoster | 33.65 | 15.32 | 5 | 35847 | 70781 | 50498491 |
Procedural haemorrhage | 33.57 | 15.32 | 21 | 35831 | 2369 | 50566903 |
Blood lactate dehydrogenase increased | 33.32 | 15.32 | 54 | 35798 | 19508 | 50549764 |
Myxoedema coma | 33.27 | 15.32 | 12 | 35840 | 387 | 50568885 |
Feeling abnormal | 32.25 | 15.32 | 25 | 35827 | 125467 | 50443805 |
Hepatic enzyme increased | 32.09 | 15.32 | 30 | 35822 | 137350 | 50431922 |
Sinus bradycardia | 32.01 | 15.32 | 43 | 35809 | 13140 | 50556132 |
Injection site erythema | 31.94 | 15.32 | 7 | 35845 | 74929 | 50494343 |
Myoclonic epilepsy | 31.86 | 15.32 | 15 | 35837 | 960 | 50568312 |
Disease progression | 31.85 | 15.32 | 14 | 35838 | 95852 | 50473420 |
Extravasation | 31.73 | 15.32 | 19 | 35833 | 1983 | 50567289 |
Cyanosis | 31.62 | 15.32 | 46 | 35806 | 15138 | 50554134 |
Left ventricular dysfunction | 31.41 | 15.32 | 38 | 35814 | 10468 | 50558804 |
Hepatitis | 31.30 | 15.32 | 69 | 35783 | 31384 | 50537888 |
Hypertriglyceridaemia | 31.16 | 15.32 | 28 | 35824 | 5463 | 50563809 |
Muscle twitching | 31.05 | 15.32 | 46 | 35806 | 15385 | 50553887 |
Brain death | 30.66 | 15.32 | 21 | 35831 | 2762 | 50566510 |
Gaze palsy | 30.23 | 15.32 | 16 | 35836 | 1317 | 50567955 |
Blood pressure immeasurable | 29.99 | 15.32 | 15 | 35837 | 1097 | 50568175 |
Myoglobinuria | 29.83 | 15.32 | 10 | 35842 | 258 | 50569014 |
Neuroleptic malignant syndrome | 29.66 | 15.32 | 38 | 35814 | 11092 | 50558180 |
Recurrence of neuromuscular blockade | 29.65 | 15.32 | 8 | 35844 | 95 | 50569177 |
Procedural hypertension | 29.44 | 15.32 | 10 | 35842 | 269 | 50569003 |
Ventricular dysfunction | 29.40 | 15.32 | 20 | 35832 | 2601 | 50566671 |
Trigemino-cardiac reflex | 29.38 | 15.32 | 7 | 35845 | 48 | 50569224 |
Acute kidney injury | 29.35 | 15.32 | 268 | 35584 | 227790 | 50341482 |
Respiratory distress | 29.35 | 15.32 | 66 | 35786 | 30423 | 50538849 |
Systemic inflammatory response syndrome | 29.16 | 15.32 | 26 | 35826 | 5023 | 50564249 |
Aspartate aminotransferase increased | 29.15 | 15.32 | 121 | 35731 | 77877 | 50491395 |
Loss of personal independence in daily activities | 28.94 | 15.32 | 7 | 35845 | 70043 | 50499229 |
Vitamin K deficiency | 28.93 | 15.32 | 11 | 35841 | 412 | 50568860 |
Somatosensory evoked potentials abnormal | 28.92 | 15.32 | 5 | 35847 | 3 | 50569269 |
Eosinophilia | 28.45 | 15.32 | 49 | 35803 | 18603 | 50550669 |
Supraventricular tachycardia | 28.44 | 15.32 | 40 | 35812 | 12761 | 50556511 |
Acute postoperative sialadenitis | 28.29 | 15.32 | 6 | 35846 | 22 | 50569250 |
Depression | 28.25 | 15.32 | 46 | 35806 | 165377 | 50403895 |
Haemodilution | 28.12 | 15.32 | 8 | 35844 | 117 | 50569155 |
Anhedonia | 27.74 | 15.32 | 34 | 35818 | 9490 | 50559782 |
Premature baby | 27.74 | 15.32 | 48 | 35804 | 18289 | 50550983 |
Abdominal pain | 27.68 | 15.32 | 81 | 35771 | 236147 | 50333125 |
Atrioventricular dissociation | 27.42 | 15.32 | 9 | 35843 | 217 | 50569055 |
Dehydration | 27.36 | 15.32 | 41 | 35811 | 152408 | 50416864 |
Skin test negative | 27.33 | 15.32 | 5 | 35847 | 6 | 50569266 |
Burkholderia test positive | 26.89 | 15.32 | 9 | 35843 | 231 | 50569041 |
Myotonia | 26.84 | 15.32 | 8 | 35844 | 139 | 50569133 |
Haematemesis | 26.67 | 15.32 | 60 | 35792 | 27665 | 50541607 |
Hypovolaemic shock | 26.61 | 15.32 | 25 | 35827 | 5163 | 50564109 |
Maternal exposure during pregnancy | 26.57 | 15.32 | 199 | 35653 | 159579 | 50409693 |
Lactic acidosis | 26.48 | 15.32 | 67 | 35785 | 33288 | 50535984 |
Oesophageal intramural haematoma | 26.35 | 15.32 | 7 | 35845 | 78 | 50569194 |
Thyrotoxic crisis | 25.91 | 15.32 | 12 | 35840 | 740 | 50568532 |
Lipoedema | 25.76 | 15.32 | 9 | 35843 | 264 | 50569008 |
Ill-defined disorder | 25.66 | 15.32 | 4 | 35848 | 54650 | 50514622 |
Gastrooesophageal reflux disease | 25.64 | 15.32 | 11 | 35841 | 76417 | 50492855 |
Depressed level of consciousness | 25.55 | 15.32 | 88 | 35764 | 51865 | 50517407 |
White blood cell count decreased | 25.52 | 15.32 | 27 | 35825 | 116695 | 50452577 |
Hypotensive transfusion reaction | 25.20 | 15.32 | 6 | 35846 | 41 | 50569231 |
Coronary artery embolism | 25.20 | 15.32 | 8 | 35844 | 173 | 50569099 |
Abscess neck | 25.11 | 15.32 | 11 | 35841 | 595 | 50568677 |
Hypoaesthesia | 25.06 | 15.32 | 32 | 35820 | 127225 | 50442047 |
Tracheal injury | 24.83 | 15.32 | 6 | 35846 | 44 | 50569228 |
Patent ductus arteriosus | 24.74 | 15.32 | 21 | 35831 | 3799 | 50565473 |
Phrenic nerve paralysis | 24.63 | 15.32 | 7 | 35845 | 102 | 50569170 |
Drug reaction with eosinophilia and systemic symptoms | 24.58 | 15.32 | 59 | 35793 | 28365 | 50540907 |
Tachypnoea | 24.50 | 15.32 | 40 | 35812 | 14537 | 50554735 |
Irregular breathing | 24.47 | 15.32 | 9 | 35843 | 307 | 50568965 |
Dyspepsia | 24.33 | 15.32 | 11 | 35841 | 74086 | 50495186 |
Hyperammonaemic encephalopathy | 24.21 | 15.32 | 16 | 35836 | 1983 | 50567289 |
Hyperkalaemia | 24.12 | 15.32 | 82 | 35770 | 48007 | 50521265 |
Anaesthetic complication cardiac | 24.10 | 15.32 | 5 | 35847 | 16 | 50569256 |
Hospitalisation | 24.06 | 15.32 | 9 | 35843 | 67928 | 50501344 |
Asthma | 23.98 | 15.32 | 17 | 35835 | 89320 | 50479952 |
Bezold-Jarisch reflex | 23.87 | 15.32 | 5 | 35847 | 17 | 50569255 |
Tracheal deviation | 23.84 | 15.32 | 6 | 35846 | 53 | 50569219 |
Ischaemic cerebral infarction | 23.79 | 15.32 | 13 | 35839 | 1140 | 50568132 |
Treatment failure | 23.75 | 15.32 | 38 | 35814 | 137599 | 50431673 |
Intensive care unit acquired weakness | 23.63 | 15.32 | 11 | 35841 | 686 | 50568586 |
Kounis syndrome | 23.56 | 15.32 | 13 | 35839 | 1162 | 50568110 |
Impaired healing | 23.48 | 15.32 | 10 | 35842 | 69776 | 50499496 |
Syncope | 23.45 | 15.32 | 23 | 35829 | 102979 | 50466293 |
Nasal congestion | 23.42 | 15.32 | 4 | 35848 | 51116 | 50518156 |
Air embolism | 23.35 | 15.32 | 8 | 35844 | 221 | 50569051 |
Electrocardiogram repolarisation abnormality | 23.31 | 15.32 | 13 | 35839 | 1187 | 50568085 |
Muscle spasms | 23.27 | 15.32 | 33 | 35819 | 125520 | 50443752 |
Musculoskeletal pain | 23.26 | 15.32 | 11 | 35841 | 72166 | 50497106 |
Anaemia | 23.22 | 15.32 | 96 | 35756 | 252360 | 50316912 |
Chest discomfort | 23.15 | 15.32 | 19 | 35833 | 92703 | 50476569 |
Endotracheal intubation | 23.13 | 15.32 | 16 | 35836 | 2138 | 50567134 |
Inadequate aseptic technique in use of product | 23.04 | 15.32 | 5 | 35847 | 21 | 50569251 |
Neck pain | 23 | 15.32 | 6 | 35846 | 57061 | 50512211 |
Acidosis | 22.79 | 15.32 | 32 | 35820 | 10195 | 50559077 |
Extubation | 22.67 | 15.32 | 5 | 35847 | 23 | 50569249 |
Cough | 22.65 | 15.32 | 91 | 35761 | 241173 | 50328099 |
Hypoxic-ischaemic encephalopathy | 22.61 | 15.32 | 20 | 35832 | 3822 | 50565450 |
Toxicity to various agents | 22.59 | 15.32 | 240 | 35612 | 212259 | 50357013 |
Suspected product contamination | 22.33 | 15.32 | 5 | 35847 | 25 | 50569247 |
Hepatic cytolysis | 22.12 | 15.32 | 28 | 35824 | 8075 | 50561197 |
Diabetes mellitus | 22.11 | 15.32 | 4 | 35848 | 49029 | 50520243 |
Sepsis syndrome | 22.02 | 15.32 | 11 | 35841 | 802 | 50568470 |
Stevens-Johnson syndrome | 21.96 | 15.32 | 48 | 35804 | 21704 | 50547568 |
Product use issue | 21.59 | 15.32 | 46 | 35806 | 149429 | 50419843 |
Cystitis | 21.52 | 15.32 | 3 | 35849 | 44561 | 50524711 |
Acquired macroglossia | 21.32 | 15.32 | 7 | 35845 | 169 | 50569103 |
Extrasystoles | 21.18 | 15.32 | 21 | 35831 | 4634 | 50564638 |
Vision blurred | 21.06 | 15.32 | 15 | 35837 | 78632 | 50490640 |
Eosinophilic pneumonia acute | 20.98 | 15.32 | 8 | 35844 | 302 | 50568970 |
Accidental overdose | 20.75 | 15.32 | 44 | 35808 | 19489 | 50549783 |
Haemoperitoneum | 20.68 | 15.32 | 16 | 35836 | 2539 | 50566733 |
Tongue oedema | 20.66 | 15.32 | 19 | 35833 | 3820 | 50565452 |
Post procedural fever | 20.52 | 15.32 | 8 | 35844 | 321 | 50568951 |
Condition aggravated | 20.44 | 15.32 | 125 | 35727 | 296933 | 50272339 |
Tidal volume decreased | 20.42 | 15.32 | 5 | 35847 | 39 | 50569233 |
Intensive care unit delirium | 20.31 | 15.32 | 5 | 35847 | 40 | 50569232 |
Atrioventricular block | 20.30 | 15.32 | 24 | 35828 | 6454 | 50562818 |
Tonic clonic movements | 20.28 | 15.32 | 12 | 35840 | 1225 | 50568047 |
Idiosyncratic drug reaction | 20.26 | 15.32 | 10 | 35842 | 711 | 50568561 |
Hypothermia | 20.23 | 15.32 | 33 | 35819 | 11983 | 50557289 |
Hepatitis C | 20.21 | 15.32 | 21 | 35831 | 4896 | 50564376 |
Urticaria | 20.21 | 15.32 | 159 | 35693 | 129402 | 50439870 |
Therapeutic product effect incomplete | 20.19 | 15.32 | 21 | 35831 | 91494 | 50477778 |
Intentional product use issue | 20.17 | 15.32 | 15 | 35837 | 76903 | 50492369 |
Emotional distress | 20.12 | 15.32 | 55 | 35797 | 28608 | 50540664 |
Brain herniation | 20.03 | 15.32 | 17 | 35835 | 3075 | 50566197 |
Laryngeal obstruction | 19.83 | 15.32 | 6 | 35846 | 110 | 50569162 |
Upper respiratory tract infection | 19.80 | 15.32 | 11 | 35841 | 65887 | 50503385 |
Rash maculo-papular | 19.59 | 15.32 | 52 | 35800 | 26589 | 50542683 |
Balance disorder | 19.52 | 15.32 | 13 | 35839 | 70577 | 50498695 |
Migraine | 19.33 | 15.32 | 15 | 35837 | 75265 | 50494007 |
Cardiac massage | 19.23 | 15.32 | 4 | 35848 | 13 | 50569259 |
Bradycardia foetal | 19.18 | 15.32 | 8 | 35844 | 383 | 50568889 |
Hypernatraemia | 19.12 | 15.32 | 23 | 35829 | 6298 | 50562974 |
Eyelid function disorder | 19.11 | 15.32 | 7 | 35845 | 236 | 50569036 |
Chronic obstructive pulmonary disease | 19.06 | 15.32 | 7 | 35845 | 53428 | 50515844 |
Dry mouth | 18.98 | 15.32 | 8 | 35844 | 56170 | 50513102 |
Epilepsy | 18.90 | 15.32 | 45 | 35807 | 21522 | 50547750 |
Transcranial electrical motor evoked potential monitoring abnormal | 18.76 | 15.32 | 3 | 35849 | 0 | 50569272 |
Bispectral index decreased | 18.76 | 15.32 | 3 | 35849 | 0 | 50569272 |
Face oedema | 18.74 | 15.32 | 40 | 35812 | 17799 | 50551473 |
Mucosal inflammation | 18.70 | 15.32 | 3 | 35849 | 40139 | 50529133 |
Partial seizures | 18.62 | 15.32 | 20 | 35832 | 4845 | 50564427 |
Peripheral nerve palsy | 18.59 | 15.32 | 4 | 35848 | 16 | 50569256 |
Long QT syndrome | 18.58 | 15.32 | 16 | 35836 | 2951 | 50566321 |
Apnoeic attack | 18.52 | 15.32 | 7 | 35845 | 258 | 50569014 |
Dry skin | 18.47 | 15.32 | 4 | 35848 | 43187 | 50526085 |
Infantile apnoea | 18.45 | 15.32 | 10 | 35842 | 863 | 50568409 |
Hepatic function abnormal | 18.43 | 15.32 | 58 | 35794 | 32623 | 50536649 |
Tracheal haemorrhage | 18.39 | 15.32 | 6 | 35846 | 142 | 50569130 |
Palpitations | 18.36 | 15.32 | 24 | 35828 | 94482 | 50474790 |
Mean arterial pressure decreased | 18.23 | 15.32 | 6 | 35846 | 146 | 50569126 |
Device programming error | 18.12 | 15.32 | 5 | 35847 | 65 | 50569207 |
Mobility decreased | 18.03 | 15.32 | 18 | 35834 | 79930 | 50489342 |
Rhinorrhoea | 17.99 | 15.32 | 7 | 35845 | 51576 | 50517696 |
Respiratory rate decreased | 17.94 | 15.32 | 16 | 35836 | 3092 | 50566180 |
Drug-induced liver injury | 17.86 | 15.32 | 52 | 35800 | 28043 | 50541229 |
Euthyroid sick syndrome | 17.84 | 15.32 | 5 | 35847 | 69 | 50569203 |
Abdominal sepsis | 17.72 | 15.32 | 11 | 35841 | 1224 | 50568048 |
Ventricular asystole | 17.65 | 15.32 | 5 | 35847 | 72 | 50569200 |
Obstructive airways disorder | 17.49 | 15.32 | 36 | 35816 | 15616 | 50553656 |
Administration site extravasation | 17.33 | 15.32 | 9 | 35843 | 712 | 50568560 |
Ammonia increased | 17.23 | 15.32 | 18 | 35834 | 4223 | 50565049 |
Bone pain | 17.16 | 15.32 | 6 | 35846 | 47223 | 50522049 |
Therapeutic product effect decreased | 17.15 | 15.32 | 45 | 35807 | 136005 | 50433267 |
Ventricular arrhythmia | 17.08 | 15.32 | 16 | 35836 | 3293 | 50565979 |
Overdose | 17.01 | 15.32 | 125 | 35727 | 99602 | 50469670 |
Polyuria | 16.94 | 15.32 | 23 | 35829 | 7098 | 50562174 |
Haemodialysis | 16.93 | 15.32 | 25 | 35827 | 8337 | 50560935 |
Uterine atony | 16.86 | 15.32 | 6 | 35846 | 186 | 50569086 |
Agitation postoperative | 16.84 | 15.32 | 4 | 35848 | 27 | 50569245 |
Fat embolism | 16.83 | 15.32 | 6 | 35846 | 187 | 50569085 |
Abdominal rigidity | 16.77 | 15.32 | 12 | 35840 | 1692 | 50567580 |
Gait inability | 16.74 | 15.32 | 3 | 35849 | 37024 | 50532248 |
Nerve stimulation test abnormal | 16.68 | 15.32 | 3 | 35849 | 3 | 50569269 |
Blood magnesium decreased | 16.60 | 15.32 | 29 | 35823 | 11131 | 50558141 |
Haematochezia | 16.44 | 15.32 | 4 | 35848 | 39878 | 50529394 |
Chemical peritonitis | 16.31 | 15.32 | 5 | 35847 | 96 | 50569176 |
Pulmonary alveolar haemorrhage | 16.20 | 15.32 | 17 | 35835 | 4010 | 50565262 |
Burning sensation | 16.13 | 15.32 | 6 | 35846 | 45440 | 50523832 |
Systolic dysfunction | 15.96 | 15.32 | 11 | 35841 | 1461 | 50567811 |
Extensor plantar response | 15.86 | 15.32 | 10 | 35842 | 1144 | 50568128 |
Hypomagnesaemia | 15.83 | 15.32 | 44 | 35808 | 23112 | 50546160 |
Osteoporosis | 15.80 | 15.32 | 6 | 35846 | 44873 | 50524399 |
Procedural dizziness | 15.80 | 15.32 | 5 | 35847 | 107 | 50569165 |
Cardiotoxicity | 15.67 | 15.32 | 22 | 35830 | 7005 | 50562267 |
Coronary artery bypass | 15.66 | 15.32 | 13 | 35839 | 2280 | 50566992 |
Suicidal ideation | 15.58 | 15.32 | 10 | 35842 | 55375 | 50513897 |
Hyperthermia | 15.56 | 15.32 | 23 | 35829 | 7673 | 50561599 |
Blood bilirubin increased | 15.51 | 15.32 | 54 | 35798 | 31984 | 50537288 |
Extrapyramidal disorder | 15.49 | 15.32 | 29 | 35823 | 11741 | 50557531 |
Central-alveolar hypoventilation | 15.47 | 15.32 | 3 | 35849 | 6 | 50569266 |
Spinal cord disorder | 15.45 | 15.32 | 10 | 35842 | 1197 | 50568075 |
Intracranial pressure increased | 15.43 | 15.32 | 17 | 35835 | 4235 | 50565037 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Anaphylactic shock | 1559.94 | 16.07 | 587 | 34183 | 12749 | 29527008 |
Propofol infusion syndrome | 1134.20 | 16.07 | 248 | 34522 | 559 | 29539198 |
Anaphylactic reaction | 752.88 | 16.07 | 444 | 34326 | 27129 | 29512628 |
Hyperthermia malignant | 575.27 | 16.07 | 169 | 34601 | 1615 | 29538142 |
Hypotension | 504.78 | 16.07 | 853 | 33917 | 193501 | 29346256 |
Cardiac arrest | 494.59 | 16.07 | 554 | 34216 | 85037 | 29454720 |
Bradycardia | 389.40 | 16.07 | 431 | 34339 | 65198 | 29474559 |
Bronchospasm | 386.57 | 16.07 | 200 | 34570 | 9409 | 29530348 |
Delayed recovery from anaesthesia | 312.00 | 16.07 | 86 | 34684 | 637 | 29539120 |
Rhabdomyolysis | 299.54 | 16.07 | 363 | 34407 | 60445 | 29479312 |
Serotonin syndrome | 268.96 | 16.07 | 197 | 34573 | 17315 | 29522442 |
Fatigue | 240.40 | 16.07 | 42 | 34728 | 316779 | 29222978 |
Anaesthetic complication | 222.39 | 16.07 | 71 | 34699 | 915 | 29538842 |
Tachycardia | 215.50 | 16.07 | 339 | 34431 | 72071 | 29467686 |
Circulatory collapse | 214.74 | 16.07 | 177 | 34593 | 18496 | 29521261 |
Metabolic acidosis | 190.42 | 16.07 | 228 | 34542 | 37434 | 29502323 |
Neuromuscular block prolonged | 167.59 | 16.07 | 48 | 34722 | 415 | 29539342 |
Pulseless electrical activity | 163.28 | 16.07 | 99 | 34671 | 6335 | 29533422 |
Ventricular fibrillation | 157.28 | 16.07 | 138 | 34632 | 15695 | 29524062 |
Diarrhoea | 151.91 | 16.07 | 103 | 34667 | 332595 | 29207162 |
Haemodynamic instability | 147.45 | 16.07 | 101 | 34669 | 7972 | 29531785 |
Oxygen saturation decreased | 137.16 | 16.07 | 213 | 34557 | 44724 | 29495033 |
Shock | 134.31 | 16.07 | 145 | 34625 | 21259 | 29518498 |
Electrocardiogram ST segment elevation | 132.01 | 16.07 | 76 | 34694 | 4416 | 29535341 |
Status epilepticus | 127.58 | 16.07 | 104 | 34666 | 10690 | 29529067 |
Blood pressure decreased | 125.66 | 16.07 | 206 | 34564 | 45271 | 29494486 |
Myoclonus | 122.26 | 16.07 | 111 | 34659 | 13198 | 29526559 |
Fall | 120.63 | 16.07 | 30 | 34740 | 177148 | 29362609 |
Death | 118.66 | 16.07 | 137 | 34633 | 341947 | 29197810 |
Respiratory depression | 116.86 | 16.07 | 109 | 34661 | 13414 | 29526343 |
Intensive care unit acquired weakness | 115.43 | 16.07 | 43 | 34727 | 900 | 29538857 |
Arthralgia | 113.58 | 16.07 | 15 | 34755 | 139602 | 29400155 |
Airway complication of anaesthesia | 108.85 | 16.07 | 27 | 34743 | 124 | 29539633 |
Decreased appetite | 102.07 | 16.07 | 23 | 34747 | 145319 | 29394438 |
Drug interaction | 101.81 | 16.07 | 480 | 34290 | 196905 | 29342852 |
Ventricular tachycardia | 100.08 | 16.07 | 128 | 34642 | 22446 | 29517311 |
Injury | 98.98 | 16.07 | 117 | 34653 | 18929 | 29520828 |
Hypoxic-ischaemic encephalopathy | 98.73 | 16.07 | 62 | 34708 | 4222 | 29535535 |
Post procedural complication | 96.10 | 16.07 | 87 | 34683 | 10302 | 29529455 |
Diabetes insipidus | 93.07 | 16.07 | 49 | 34721 | 2385 | 29537372 |
Hypoxia | 90.61 | 16.07 | 183 | 34587 | 47196 | 29492561 |
Toxic epidermal necrolysis | 90.20 | 16.07 | 109 | 34661 | 18044 | 29521713 |
Dizziness | 88.65 | 16.07 | 57 | 34713 | 189627 | 29350130 |
Drug reaction with eosinophilia and systemic symptoms | 88.61 | 16.07 | 135 | 34635 | 27857 | 29511900 |
Multiple organ dysfunction syndrome | 87.15 | 16.07 | 214 | 34556 | 62902 | 29476855 |
Product dose omission issue | 86.99 | 16.07 | 7 | 34763 | 96376 | 29443381 |
Laryngospasm | 85.94 | 16.07 | 38 | 34732 | 1252 | 29538505 |
Hypertriglyceridaemia | 84.10 | 16.07 | 70 | 34700 | 7405 | 29532352 |
Procedural complication | 81.81 | 16.07 | 54 | 34716 | 4006 | 29535751 |
Blood creatine phosphokinase increased | 81.32 | 16.07 | 160 | 34610 | 40484 | 29499273 |
Respiratory acidosis | 81.05 | 16.07 | 55 | 34715 | 4273 | 29535484 |
Anaphylactoid shock | 80.80 | 16.07 | 26 | 34744 | 344 | 29539413 |
Trigemino-cardiac reflex | 80.51 | 16.07 | 22 | 34748 | 157 | 29539600 |
Negative pressure pulmonary oedema | 80.18 | 16.07 | 23 | 34747 | 200 | 29539557 |
Asthenia | 76.84 | 16.07 | 84 | 34686 | 215166 | 29324591 |
Anaesthetic complication neurological | 75.75 | 16.07 | 24 | 34746 | 301 | 29539456 |
Tachypnoea | 75.48 | 16.07 | 91 | 34679 | 15024 | 29524733 |
Arteriospasm coronary | 74.31 | 16.07 | 43 | 34727 | 2522 | 29537235 |
Headache | 73.78 | 16.07 | 58 | 34712 | 173949 | 29365808 |
Fear | 73.37 | 16.07 | 72 | 34698 | 9432 | 29530325 |
Pain in extremity | 72.60 | 16.07 | 20 | 34750 | 110413 | 29429344 |
Procedural hypotension | 71.74 | 16.07 | 30 | 34740 | 860 | 29538897 |
Pulse absent | 70.59 | 16.07 | 54 | 34716 | 5059 | 29534698 |
Intestinal ischaemia | 69.80 | 16.07 | 60 | 34710 | 6632 | 29533125 |
Nausea | 68.64 | 16.07 | 149 | 34621 | 289106 | 29250651 |
Apnoea | 66.28 | 16.07 | 56 | 34714 | 6046 | 29533711 |
Respiratory arrest | 65.94 | 16.07 | 113 | 34657 | 25720 | 29514037 |
Stress cardiomyopathy | 65.83 | 16.07 | 34 | 34736 | 1590 | 29538167 |
Vasoplegia syndrome | 65.28 | 16.07 | 33 | 34737 | 1475 | 29538282 |
Malaise | 64.18 | 16.07 | 56 | 34714 | 159546 | 29380211 |
Autonomic nervous system imbalance | 64.00 | 16.07 | 38 | 34732 | 2338 | 29537419 |
Renal injury | 63.77 | 16.07 | 69 | 34701 | 10133 | 29529624 |
Transmission of an infectious agent via product | 62.30 | 16.07 | 18 | 34752 | 161 | 29539596 |
Kounis syndrome | 62.03 | 16.07 | 34 | 34736 | 1795 | 29537962 |
Spinal muscular atrophy | 61.99 | 16.07 | 20 | 34750 | 267 | 29539490 |
Anaemia | 61.67 | 16.07 | 88 | 34682 | 200863 | 29338894 |
Abdominal pain | 61.39 | 16.07 | 42 | 34728 | 135315 | 29404442 |
Seizure like phenomena | 60.38 | 16.07 | 24 | 34746 | 602 | 29539155 |
Agitation | 59.51 | 16.07 | 163 | 34607 | 51141 | 29488616 |
Weight decreased | 59.40 | 16.07 | 54 | 34716 | 150851 | 29388906 |
Drug level changed | 58.83 | 16.07 | 20 | 34750 | 317 | 29539440 |
Brain oedema | 58.46 | 16.07 | 72 | 34698 | 12148 | 29527609 |
Cyanosis | 58.17 | 16.07 | 69 | 34701 | 11198 | 29528559 |
Hypoventilation | 57.76 | 16.07 | 38 | 34732 | 2803 | 29536954 |
Muscle rigidity | 57.69 | 16.07 | 63 | 34707 | 9348 | 29530409 |
Post procedural fever | 56.95 | 16.07 | 16 | 34754 | 128 | 29539629 |
Dyspnoea | 56.76 | 16.07 | 196 | 34574 | 326536 | 29213221 |
Peripheral swelling | 56.47 | 16.07 | 5 | 34765 | 63734 | 29476023 |
Febrile neutropenia | 56.20 | 16.07 | 31 | 34739 | 112209 | 29427548 |
Cardio-respiratory arrest | 55.96 | 16.07 | 158 | 34612 | 50443 | 29489314 |
Anhedonia | 54.56 | 16.07 | 54 | 34716 | 7146 | 29532611 |
Neuropathy peripheral | 54.54 | 16.07 | 9 | 34761 | 71018 | 29468739 |
Ventricular arrhythmia | 53.63 | 16.07 | 44 | 34726 | 4560 | 29535197 |
Acute respiratory distress syndrome | 52.94 | 16.07 | 96 | 34674 | 22839 | 29516918 |
Respiratory failure | 52.68 | 16.07 | 240 | 34530 | 96891 | 29442866 |
Constipation | 52.31 | 16.07 | 35 | 34735 | 114125 | 29425632 |
Tryptase increased | 51.76 | 16.07 | 16 | 34754 | 184 | 29539573 |
Erythema | 51.25 | 16.07 | 200 | 34570 | 75406 | 29464351 |
Malignant neoplasm progression | 51.17 | 16.07 | 12 | 34758 | 73847 | 29465910 |
Resuscitation | 50.94 | 16.07 | 26 | 34744 | 1186 | 29538571 |
Dystonia | 50.82 | 16.07 | 60 | 34710 | 9689 | 29530068 |
Brain injury | 50.66 | 16.07 | 46 | 34724 | 5466 | 29534291 |
Pulmonary alveolar haemorrhage | 50.49 | 16.07 | 49 | 34721 | 6331 | 29533426 |
Weight increased | 50.15 | 16.07 | 14 | 34756 | 76653 | 29463104 |
Disease progression | 49.91 | 16.07 | 17 | 34753 | 81899 | 29457858 |
Dyskinesia | 47.61 | 16.07 | 85 | 34685 | 19976 | 29519781 |
Neonatal respiratory depression | 47.56 | 16.07 | 18 | 34752 | 394 | 29539363 |
Neuromuscular blockade | 47.50 | 16.07 | 15 | 34755 | 186 | 29539571 |
Neutropenia | 46.26 | 16.07 | 52 | 34718 | 131659 | 29408098 |
Oedema peripheral | 45.78 | 16.07 | 33 | 34737 | 103524 | 29436233 |
Blood pressure measurement | 45.37 | 16.07 | 14 | 34756 | 160 | 29539597 |
Blood lactic acid increased | 45.10 | 16.07 | 44 | 34726 | 5722 | 29534035 |
Necrosis ischaemic | 45.01 | 16.07 | 15 | 34755 | 223 | 29539534 |
Oxygen saturation immeasurable | 44.69 | 16.07 | 10 | 34760 | 26 | 29539731 |
Sinus arrest | 43.90 | 16.07 | 25 | 34745 | 1422 | 29538335 |
Hyperammonaemia | 43.89 | 16.07 | 43 | 34727 | 5620 | 29534137 |
Feeling abnormal | 43.85 | 16.07 | 6 | 34764 | 54439 | 29485318 |
Endotracheal intubation complication | 43.76 | 16.07 | 16 | 34754 | 317 | 29539440 |
Insomnia | 43.72 | 16.07 | 25 | 34745 | 88736 | 29451021 |
Product contamination | 43.72 | 16.07 | 19 | 34751 | 600 | 29539157 |
Pneumonia | 43.68 | 16.07 | 211 | 34559 | 319961 | 29219796 |
Back pain | 43.41 | 16.07 | 34 | 34736 | 102250 | 29437507 |
White blood cell count decreased | 43.22 | 16.07 | 22 | 34748 | 83340 | 29456417 |
Hepatorenal failure | 43.14 | 16.07 | 18 | 34752 | 513 | 29539244 |
Acidosis | 42.94 | 16.07 | 55 | 34715 | 9650 | 29530107 |
Hospitalisation | 42.43 | 16.07 | 3 | 34767 | 45985 | 29493772 |
Cough | 42.39 | 16.07 | 52 | 34718 | 126675 | 29413082 |
Type I hypersensitivity | 42.18 | 16.07 | 22 | 34748 | 1050 | 29538707 |
Endotracheal intubation | 40.88 | 16.07 | 30 | 34740 | 2639 | 29537118 |
Respiratory tract infection bacterial | 40.65 | 16.07 | 18 | 34752 | 595 | 29539162 |
Pneumococcal sepsis | 40.58 | 16.07 | 20 | 34750 | 846 | 29538911 |
Anaesthetic complication cardiac | 40.06 | 16.07 | 9 | 34761 | 24 | 29539733 |
Anaphylactoid reaction | 39.50 | 16.07 | 26 | 34744 | 1919 | 29537838 |
Urinary tract infection | 39.18 | 16.07 | 18 | 34752 | 72336 | 29467421 |
Sinus tachycardia | 38.55 | 16.07 | 66 | 34704 | 15003 | 29524754 |
Torsade de pointes | 38.08 | 16.07 | 43 | 34727 | 6618 | 29533139 |
Burkholderia test positive | 37.88 | 16.07 | 20 | 34750 | 979 | 29538778 |
Pancytopenia | 37.41 | 16.07 | 26 | 34744 | 83142 | 29456615 |
Cardiac failure congestive | 37.10 | 16.07 | 22 | 34748 | 76559 | 29463198 |
Emotional distress | 37.06 | 16.07 | 62 | 34708 | 13833 | 29525924 |
Anticholinergic syndrome | 37.05 | 16.07 | 19 | 34751 | 875 | 29538882 |
Coma blister | 36.76 | 16.07 | 10 | 34760 | 70 | 29539687 |
Hypotonic-hyporesponsive episode | 36.57 | 16.07 | 8 | 34762 | 18 | 29539739 |
Dehydration | 36.39 | 16.07 | 49 | 34721 | 114699 | 29425058 |
Airway peak pressure increased | 36.27 | 16.07 | 8 | 34762 | 19 | 29539738 |
Hypercapnia | 36.03 | 16.07 | 32 | 34738 | 3694 | 29536063 |
Procedural haemorrhage | 35.73 | 16.07 | 26 | 34744 | 2257 | 29537500 |
Opisthotonus | 35.58 | 16.07 | 15 | 34755 | 439 | 29539318 |
Brugada syndrome | 35.28 | 16.07 | 17 | 34753 | 684 | 29539073 |
Mean arterial pressure decreased | 35.16 | 16.07 | 11 | 34759 | 132 | 29539625 |
Lactic acidosis | 34.95 | 16.07 | 96 | 34674 | 30151 | 29509606 |
Urticaria | 34.94 | 16.07 | 142 | 34628 | 54518 | 29485239 |
Paraesthesia | 34.89 | 16.07 | 10 | 34760 | 53835 | 29485922 |
Haemodialysis | 34.33 | 16.07 | 50 | 34720 | 9904 | 29529853 |
Increased bronchial secretion | 34.23 | 16.07 | 22 | 34748 | 1559 | 29538198 |
Delirium | 34.16 | 16.07 | 113 | 34657 | 39284 | 29500473 |
Post procedural haemorrhage | 34.01 | 16.07 | 43 | 34727 | 7448 | 29532309 |
Pulmonary oedema | 33.92 | 16.07 | 119 | 34651 | 42616 | 29497141 |
Therapeutic product effect prolonged | 33.24 | 16.07 | 12 | 34758 | 229 | 29539528 |
Oculocardiac reflex | 33.21 | 16.07 | 9 | 34761 | 62 | 29539695 |
Hepatitis fulminant | 33.20 | 16.07 | 30 | 34740 | 3541 | 29536216 |
Multiple-drug resistance | 32.84 | 16.07 | 31 | 34739 | 3869 | 29535888 |
Muscle spasms | 32.52 | 16.07 | 18 | 34752 | 65064 | 29474693 |
Intracranial pressure increased | 31.86 | 16.07 | 29 | 34741 | 3456 | 29536301 |
Superinfection | 31.80 | 16.07 | 23 | 34747 | 1978 | 29537779 |
Spinal cord infarction | 31.57 | 16.07 | 12 | 34758 | 266 | 29539491 |
Areflexia | 31.41 | 16.07 | 26 | 34744 | 2728 | 29537029 |
Product contamination microbial | 31.30 | 16.07 | 15 | 34755 | 596 | 29539161 |
Postoperative delirium | 31.21 | 16.07 | 8 | 34762 | 43 | 29539714 |
Cellulitis | 30.66 | 16.07 | 8 | 34762 | 45832 | 29493925 |
Chest pain | 30.51 | 16.07 | 53 | 34717 | 111920 | 29427837 |
Metabolic disorder | 30.41 | 16.07 | 29 | 34741 | 3666 | 29536091 |
Neuroleptic malignant syndrome | 30.39 | 16.07 | 62 | 34708 | 16086 | 29523671 |
Sputum increased | 30.28 | 16.07 | 22 | 34748 | 1905 | 29537852 |
Nodal rhythm | 30.15 | 16.07 | 19 | 34751 | 1301 | 29538456 |
Symmetrical drug-related intertriginous and flexural exanthema | 30.08 | 16.07 | 11 | 34759 | 218 | 29539539 |
Heparin-induced thrombocytopenia | 29.94 | 16.07 | 33 | 34737 | 4946 | 29534811 |
Drug intolerance | 29.53 | 16.07 | 10 | 34760 | 48369 | 29491388 |
PCO2 increased | 29.41 | 16.07 | 14 | 34756 | 548 | 29539209 |
Post procedural hypotension | 29.41 | 16.07 | 8 | 34762 | 56 | 29539701 |
Vomiting | 29.39 | 16.07 | 139 | 34631 | 212121 | 29327636 |
Inappropriate schedule of product administration | 29.30 | 16.07 | 8 | 34762 | 44464 | 29495293 |
Chromaturia | 28.79 | 16.07 | 53 | 34717 | 12749 | 29527008 |
Electrocardiogram ST-T segment elevation | 28.74 | 16.07 | 5 | 34765 | 0 | 29539757 |
Syncope | 28.68 | 16.07 | 32 | 34738 | 81339 | 29458418 |
Influenza | 28.61 | 16.07 | 7 | 34763 | 41874 | 29497883 |
Sodium retention | 28.05 | 16.07 | 8 | 34762 | 68 | 29539689 |
Plasma cell myeloma | 27.82 | 16.07 | 5 | 34765 | 37110 | 29502647 |
Suicidal ideation | 27.54 | 16.07 | 4 | 34766 | 34712 | 29505045 |
Pneumomediastinum | 27.49 | 16.07 | 20 | 34750 | 1736 | 29538021 |
Electrocardiogram T wave inversion | 27.37 | 16.07 | 21 | 34749 | 1976 | 29537781 |
Unresponsive to stimuli | 27.31 | 16.07 | 78 | 34692 | 25048 | 29514709 |
Recurrence of neuromuscular blockade | 27.31 | 16.07 | 9 | 34761 | 129 | 29539628 |
Hypotonia | 27.27 | 16.07 | 37 | 34733 | 6865 | 29532892 |
Ischaemic cerebral infarction | 26.88 | 16.07 | 16 | 34754 | 989 | 29538768 |
Balance disorder | 26.84 | 16.07 | 5 | 34765 | 36165 | 29503592 |
Disseminated intravascular coagulation | 26.74 | 16.07 | 67 | 34703 | 19913 | 29519844 |
Acute pulmonary oedema | 26.26 | 16.07 | 36 | 34734 | 6743 | 29533014 |
Lower respiratory tract infection bacterial | 26.21 | 16.07 | 11 | 34759 | 318 | 29539439 |
Disease complication | 26.12 | 16.07 | 22 | 34748 | 2364 | 29537393 |
Coagulopathy | 26.04 | 16.07 | 62 | 34708 | 17845 | 29521912 |
Mucosal ulceration | 26.02 | 16.07 | 15 | 34755 | 873 | 29538884 |
Renin increased | 25.96 | 16.07 | 8 | 34762 | 91 | 29539666 |
Stomatitis | 25.75 | 16.07 | 6 | 34764 | 37107 | 29502650 |
Gait disturbance | 25.68 | 16.07 | 29 | 34741 | 73320 | 29466437 |
Electrocardiogram QT prolonged | 25.61 | 16.07 | 97 | 34673 | 36040 | 29503717 |
Locked-in syndrome | 25.53 | 16.07 | 10 | 34760 | 241 | 29539516 |
Pseudocholinesterase deficiency | 25.48 | 16.07 | 6 | 34764 | 21 | 29539736 |
Generalised tonic-clonic seizure | 25.43 | 16.07 | 64 | 34706 | 19075 | 29520682 |
Depression | 25.35 | 16.07 | 38 | 34732 | 85109 | 29454648 |
Motor neurone disease | 25.17 | 16.07 | 11 | 34759 | 352 | 29539405 |
Abdominal pain upper | 24.96 | 16.07 | 21 | 34749 | 60972 | 29478785 |
Acidosis hyperchloraemic | 24.94 | 16.07 | 11 | 34759 | 360 | 29539397 |
Cerebral ischaemia | 24.73 | 16.07 | 32 | 34738 | 5671 | 29534086 |
Diabetes mellitus | 24.71 | 16.07 | 8 | 34762 | 39823 | 29499934 |
Hepatic cytolysis | 24.64 | 16.07 | 39 | 34731 | 8308 | 29531449 |
Neonatal hypoxia | 24.61 | 16.07 | 11 | 34759 | 372 | 29539385 |
Subcutaneous emphysema | 24.48 | 16.07 | 15 | 34755 | 977 | 29538780 |
Atrioventricular block complete | 24.44 | 16.07 | 38 | 34732 | 7973 | 29531784 |
Hypothermia | 24.34 | 16.07 | 41 | 34729 | 9198 | 29530559 |
Stoma closure | 24.32 | 16.07 | 8 | 34762 | 114 | 29539643 |
Suspected product contamination | 24.29 | 16.07 | 7 | 34763 | 62 | 29539695 |
Local anaesthetic systemic toxicity | 24.26 | 16.07 | 9 | 34761 | 186 | 29539571 |
Paroxysmal sympathetic hyperactivity | 24.11 | 16.07 | 6 | 34764 | 28 | 29539729 |
Contusion | 23.72 | 16.07 | 4 | 34766 | 31091 | 29508666 |
Weight bearing difficulty | 23.64 | 16.07 | 14 | 34756 | 857 | 29538900 |
Bronchitis | 23.60 | 16.07 | 7 | 34763 | 36861 | 29502896 |
Chills | 23.56 | 16.07 | 154 | 34616 | 71146 | 29468611 |
Systemic inflammatory response syndrome | 23.53 | 16.07 | 32 | 34738 | 5949 | 29533808 |
Blood catecholamines increased | 23.25 | 16.07 | 5 | 34765 | 10 | 29539747 |
Dyspnoea exertional | 23.23 | 16.07 | 7 | 34763 | 36483 | 29503274 |
Rash maculo-papular | 23.17 | 16.07 | 72 | 34698 | 24217 | 29515540 |
Unwanted awareness during anaesthesia | 23.14 | 16.07 | 6 | 34764 | 34 | 29539723 |
Myoglobin blood increased | 23.10 | 16.07 | 19 | 34751 | 1976 | 29537781 |
Suspected product quality issue | 23.07 | 16.07 | 8 | 34762 | 135 | 29539622 |
Haemoglobin decreased | 23.06 | 16.07 | 59 | 34711 | 108316 | 29431441 |
End-tidal CO2 increased | 22.93 | 16.07 | 5 | 34765 | 11 | 29539746 |
Post-injection delirium sedation syndrome | 22.91 | 16.07 | 11 | 34759 | 439 | 29539318 |
Electroencephalogram abnormal | 22.47 | 16.07 | 20 | 34750 | 2315 | 29537442 |
Upper airway obstruction | 22.42 | 16.07 | 12 | 34758 | 604 | 29539153 |
Coronary artery disease | 22.39 | 16.07 | 12 | 34758 | 44178 | 29495579 |
Conversion disorder | 22.35 | 16.07 | 10 | 34760 | 339 | 29539418 |
Pruritus | 22.34 | 16.07 | 67 | 34703 | 116782 | 29422975 |
Hyperventilation | 22.27 | 16.07 | 20 | 34750 | 2342 | 29537415 |
Brain death | 22.21 | 16.07 | 20 | 34750 | 2350 | 29537407 |
Trismus | 22.19 | 16.07 | 20 | 34750 | 2353 | 29537404 |
Periorbital swelling | 22.05 | 16.07 | 10 | 34760 | 350 | 29539407 |
Hypoglycaemia | 21.88 | 16.07 | 15 | 34755 | 48331 | 29491426 |
Neutrophil count decreased | 21.83 | 16.07 | 12 | 34758 | 43555 | 29496202 |
Septic shock | 21.82 | 16.07 | 137 | 34633 | 62423 | 29477334 |
Mechanical ventilation | 21.57 | 16.07 | 17 | 34753 | 1663 | 29538094 |
Ventricular extrasystoles | 21.55 | 16.07 | 42 | 34728 | 10540 | 29529217 |
Laryngeal oedema | 21.51 | 16.07 | 22 | 34748 | 3026 | 29536731 |
Musculoskeletal pain | 21.49 | 16.07 | 4 | 34766 | 28949 | 29510808 |
Acute kidney injury | 21.17 | 16.07 | 433 | 34337 | 264834 | 29274923 |
Hyperthermia | 21.15 | 16.07 | 39 | 34731 | 9391 | 29530366 |
Long QT syndrome | 21.05 | 16.07 | 19 | 34751 | 2239 | 29537518 |
Unevaluable event | 21.04 | 16.07 | 80 | 34690 | 29771 | 29509986 |
Neuromyopathy | 20.68 | 16.07 | 13 | 34757 | 886 | 29538871 |
Herpes zoster | 20.57 | 16.07 | 5 | 34765 | 30047 | 29509710 |
Dialysis | 20.17 | 16.07 | 40 | 34730 | 10168 | 29529589 |
Loss of personal independence in daily activities | 20.02 | 16.07 | 3 | 34767 | 25437 | 29514320 |
Nystagmus | 19.98 | 16.07 | 25 | 34745 | 4284 | 29535473 |
Continuous haemodiafiltration | 19.90 | 16.07 | 13 | 34757 | 947 | 29538810 |
Incorrect drug administration rate | 19.80 | 16.07 | 14 | 34756 | 1162 | 29538595 |
Epistaxis | 19.72 | 16.07 | 19 | 34751 | 51685 | 29488072 |
Air embolism | 19.67 | 16.07 | 7 | 34763 | 128 | 29539629 |
Congenital megaureter | 19.67 | 16.07 | 7 | 34763 | 128 | 29539629 |
Electrocardiogram ST segment depression | 19.62 | 16.07 | 18 | 34752 | 2167 | 29537590 |
Chronic obstructive pulmonary disease | 19.50 | 16.07 | 12 | 34758 | 40943 | 29498814 |
Malignant catatonia | 19.34 | 16.07 | 8 | 34762 | 223 | 29539534 |
Premature recovery from anaesthesia | 19.33 | 16.07 | 4 | 34766 | 6 | 29539751 |
Chest X-ray abnormal | 19.19 | 16.07 | 23 | 34747 | 3771 | 29535986 |
Systolic anterior motion of mitral valve | 19.19 | 16.07 | 5 | 34765 | 29 | 29539728 |
Priapism | 19.17 | 16.07 | 25 | 34745 | 4463 | 29535294 |
Migraine with aura | 19.10 | 16.07 | 10 | 34760 | 481 | 29539276 |
Lymphadenectomy | 18.98 | 16.07 | 8 | 34762 | 234 | 29539523 |
General physical health deterioration | 18.93 | 16.07 | 60 | 34710 | 102797 | 29436960 |
Treatment failure | 18.76 | 16.07 | 10 | 34760 | 36929 | 29502828 |
Drug withdrawal syndrome | 18.74 | 16.07 | 55 | 34715 | 17929 | 29521828 |
Sedation complication | 18.71 | 16.07 | 14 | 34756 | 1268 | 29538489 |
Eosinophilia | 18.70 | 16.07 | 63 | 34707 | 22098 | 29517659 |
Capillary nail refill test abnormal | 18.63 | 16.07 | 5 | 34765 | 33 | 29539724 |
Drug ineffective | 18.57 | 16.07 | 558 | 34212 | 362612 | 29177145 |
Seizure | 18.55 | 16.07 | 179 | 34591 | 92944 | 29446813 |
Oliguria | 18.35 | 16.07 | 32 | 34738 | 7380 | 29532377 |
Urinary bladder rupture | 18.33 | 16.07 | 6 | 34764 | 84 | 29539673 |
Clonus | 18.32 | 16.07 | 18 | 34752 | 2360 | 29537397 |
Fear of death | 18.19 | 16.07 | 10 | 34760 | 531 | 29539226 |
Skin test negative | 18.14 | 16.07 | 5 | 34765 | 37 | 29539720 |
Renal impairment | 18.05 | 16.07 | 160 | 34610 | 81173 | 29458584 |
Eye movement disorder | 18.03 | 16.07 | 22 | 34748 | 3674 | 29536083 |
Sinusitis | 17.89 | 16.07 | 9 | 34761 | 34341 | 29505416 |
Pleural effusion | 17.84 | 16.07 | 36 | 34734 | 71872 | 29467885 |
Dry skin | 17.77 | 16.07 | 3 | 34767 | 23304 | 29516453 |
Sinus bradycardia | 17.77 | 16.07 | 41 | 34729 | 11562 | 29528195 |
Hyperleukocytosis | 17.74 | 16.07 | 15 | 34755 | 1620 | 29538137 |
Electrocardiogram QRS complex prolonged | 17.72 | 16.07 | 23 | 34747 | 4087 | 29535670 |
Bronchial disorder | 17.67 | 16.07 | 13 | 34757 | 1148 | 29538609 |
Depressed level of consciousness | 17.60 | 16.07 | 88 | 34682 | 36854 | 29502903 |
Hyperkalaemia | 17.55 | 16.07 | 128 | 34642 | 61264 | 29478493 |
Transcranial electrical motor evoked potential monitoring abnormal | 17.46 | 16.07 | 4 | 34766 | 12 | 29539745 |
Haematuria traumatic | 17.37 | 16.07 | 7 | 34763 | 182 | 29539575 |
Mydriasis | 17.37 | 16.07 | 28 | 34742 | 6057 | 29533700 |
Pupil fixed | 17.27 | 16.07 | 15 | 34755 | 1681 | 29538076 |
Klebsiella infection | 17.25 | 16.07 | 31 | 34739 | 7318 | 29532439 |
Light anaesthesia | 17.24 | 16.07 | 3 | 34767 | 0 | 29539757 |
Therapeutic response prolonged | 17.24 | 16.07 | 3 | 34767 | 0 | 29539757 |
Hypernatraemia | 17.14 | 16.07 | 31 | 34739 | 7355 | 29532402 |
Apnoeic attack | 17.03 | 16.07 | 8 | 34762 | 304 | 29539453 |
Anaesthetic complication pulmonary | 16.99 | 16.07 | 4 | 34766 | 14 | 29539743 |
Skin test positive | 16.98 | 16.07 | 8 | 34762 | 306 | 29539451 |
Obstructive airways disorder | 16.95 | 16.07 | 39 | 34731 | 10977 | 29528780 |
Respiratory alkalosis | 16.91 | 16.07 | 14 | 34756 | 1469 | 29538288 |
Complication of device removal | 16.81 | 16.07 | 5 | 34765 | 50 | 29539707 |
Sleep disorder | 16.80 | 16.07 | 4 | 34766 | 24382 | 29515375 |
Aspiration | 16.74 | 16.07 | 37 | 34733 | 10143 | 29529614 |
Mixed liver injury | 16.69 | 16.07 | 16 | 34754 | 2035 | 29537722 |
Hyponatraemia | 16.66 | 16.07 | 34 | 34736 | 67599 | 29472158 |
Cardiogenic shock | 16.59 | 16.07 | 55 | 34715 | 19135 | 29520622 |
Myocardial infarction | 16.57 | 16.07 | 70 | 34700 | 110226 | 29429531 |
Abdominal compartment syndrome | 16.52 | 16.07 | 11 | 34759 | 828 | 29538929 |
Atonic urinary bladder | 16.19 | 16.07 | 4 | 34766 | 18 | 29539739 |
Hepatitis acute | 16.13 | 16.07 | 28 | 34742 | 6434 | 29533323 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Anaphylactic shock | 3676.44 | 14.01 | 1321 | 64752 | 29007 | 64403652 |
Anaphylactic reaction | 1720.67 | 14.01 | 996 | 65077 | 67668 | 64364991 |
Propofol infusion syndrome | 1666.48 | 14.01 | 376 | 65697 | 1241 | 64431418 |
Hypotension | 1142.92 | 14.01 | 1658 | 64415 | 379316 | 64053343 |
Cardiac arrest | 1107.53 | 14.01 | 1052 | 65021 | 153012 | 64279647 |
Bronchospasm | 1037.45 | 14.01 | 486 | 65587 | 21196 | 64411463 |
Hyperthermia malignant | 820.22 | 14.01 | 232 | 65841 | 2227 | 64430432 |
Bradycardia | 630.70 | 14.01 | 688 | 65385 | 117531 | 64315128 |
Delayed recovery from anaesthesia | 628.69 | 14.01 | 170 | 65903 | 1358 | 64431301 |
Serotonin syndrome | 589.99 | 14.01 | 413 | 65660 | 38869 | 64393790 |
Circulatory collapse | 545.03 | 14.01 | 371 | 65702 | 33361 | 64399298 |
Tachycardia | 532.71 | 14.01 | 709 | 65364 | 148870 | 64283789 |
Rhabdomyolysis | 454.75 | 14.01 | 514 | 65559 | 91212 | 64341447 |
Fatigue | 446.68 | 14.01 | 110 | 65963 | 748620 | 63684039 |
Neuromuscular block prolonged | 366.12 | 14.01 | 101 | 65972 | 876 | 64431783 |
Stress cardiomyopathy | 356.58 | 14.01 | 179 | 65894 | 9078 | 64423581 |
Ventricular fibrillation | 351.47 | 14.01 | 248 | 65825 | 23612 | 64409047 |
Anaesthetic complication | 329.25 | 14.01 | 117 | 65956 | 2462 | 64430197 |
Arthralgia | 327.21 | 14.01 | 36 | 66037 | 442224 | 63990435 |
Diarrhoea | 325.67 | 14.01 | 168 | 65905 | 722536 | 63710123 |
Pulseless electrical activity | 324.13 | 14.01 | 187 | 65886 | 12552 | 64420107 |
Status epilepticus | 318.69 | 14.01 | 225 | 65848 | 21438 | 64411221 |
Metabolic acidosis | 315.30 | 14.01 | 376 | 65697 | 70582 | 64362077 |
Haemodynamic instability | 309.51 | 14.01 | 192 | 65881 | 14720 | 64417939 |
Ventricular tachycardia | 302.16 | 14.01 | 263 | 65810 | 34002 | 64398657 |
Shock | 288.86 | 14.01 | 269 | 65804 | 37971 | 64394688 |
Blood pressure decreased | 287.28 | 14.01 | 396 | 65677 | 85803 | 64346856 |
Drug interaction | 283.46 | 14.01 | 914 | 65159 | 361169 | 64071490 |
Fall | 270.84 | 14.01 | 50 | 66023 | 416776 | 64015883 |
Oxygen saturation decreased | 262.14 | 14.01 | 426 | 65647 | 106750 | 64325909 |
Myoclonus | 254.76 | 14.01 | 209 | 65864 | 24909 | 64407750 |
Multiple organ dysfunction syndrome | 239.77 | 14.01 | 397 | 65676 | 101016 | 64331643 |
Electrocardiogram ST segment elevation | 229.65 | 14.01 | 123 | 65950 | 7136 | 64425523 |
Airway complication of anaesthesia | 223.07 | 14.01 | 57 | 66016 | 355 | 64432304 |
Procedural hypotension | 219.85 | 14.01 | 80 | 65993 | 1806 | 64430853 |
Diabetes insipidus | 215.01 | 14.01 | 101 | 65972 | 4420 | 64428239 |
Hypoxia | 202.88 | 14.01 | 341 | 65732 | 87808 | 64344851 |
Apnoea | 200.73 | 14.01 | 128 | 65945 | 10294 | 64422365 |
Joint swelling | 197.06 | 14.01 | 5 | 66068 | 215377 | 64217282 |
Respiratory depression | 196.76 | 14.01 | 175 | 65898 | 23268 | 64409391 |
Headache | 193.13 | 14.01 | 156 | 65917 | 529311 | 63903348 |
Anaphylactoid shock | 188.97 | 14.01 | 57 | 66016 | 697 | 64431962 |
Post procedural complication | 186.40 | 14.01 | 163 | 65910 | 21190 | 64411469 |
Blood creatine phosphokinase increased | 181.59 | 14.01 | 260 | 65813 | 58298 | 64374361 |
Respiratory acidosis | 177.39 | 14.01 | 116 | 65957 | 9739 | 64422920 |
Pain in extremity | 175.28 | 14.01 | 47 | 66026 | 303038 | 64129621 |
Dystonia | 174.79 | 14.01 | 149 | 65924 | 18716 | 64413943 |
Dizziness | 173.34 | 14.01 | 114 | 65959 | 430049 | 64002610 |
Laryngospasm | 173.25 | 14.01 | 80 | 65993 | 3365 | 64429294 |
Procedural complication | 169.91 | 14.01 | 101 | 65972 | 7164 | 64425495 |
Nasopharyngitis | 167.36 | 14.01 | 8 | 66065 | 196065 | 64236594 |
Malaise | 166.53 | 14.01 | 100 | 65973 | 396147 | 64036512 |
Nausea | 165.05 | 14.01 | 350 | 65723 | 785450 | 63647209 |
Intestinal ischaemia | 156.18 | 14.01 | 114 | 65959 | 11435 | 64421224 |
Decreased appetite | 154.56 | 14.01 | 48 | 66025 | 281241 | 64151418 |
Arteriospasm coronary | 146.44 | 14.01 | 83 | 65990 | 5382 | 64427277 |
Peripheral swelling | 144.77 | 14.01 | 21 | 66052 | 209132 | 64223527 |
Drug intolerance | 142.12 | 14.01 | 14 | 66059 | 187978 | 64244681 |
Product dose omission issue | 140.89 | 14.01 | 17 | 66056 | 194730 | 64237929 |
Alopecia | 137.49 | 14.01 | 8 | 66065 | 165682 | 64266977 |
Weight increased | 137.48 | 14.01 | 26 | 66047 | 213322 | 64219337 |
Hypoventilation | 136.56 | 14.01 | 82 | 65991 | 5924 | 64426735 |
Dyspnoea | 136.30 | 14.01 | 338 | 65735 | 718336 | 63714323 |
Rheumatoid arthritis | 136.13 | 14.01 | 8 | 66065 | 164286 | 64268373 |
Abdominal discomfort | 134.17 | 14.01 | 15 | 66058 | 182307 | 64250352 |
Tryptase increased | 133.54 | 14.01 | 39 | 66034 | 423 | 64432236 |
Anaphylactoid reaction | 132.49 | 14.01 | 74 | 65999 | 4664 | 64427995 |
Intensive care unit acquired weakness | 132.39 | 14.01 | 54 | 66019 | 1673 | 64430986 |
Cardio-respiratory arrest | 131.60 | 14.01 | 303 | 65770 | 98090 | 64334569 |
Anaesthetic complication neurological | 127.18 | 14.01 | 39 | 66034 | 506 | 64432153 |
Unwanted awareness during anaesthesia | 123.31 | 14.01 | 33 | 66040 | 252 | 64432407 |
Torsade de pointes | 121.26 | 14.01 | 117 | 65956 | 17246 | 64415413 |
Type I hypersensitivity | 119.94 | 14.01 | 63 | 66010 | 3511 | 64429148 |
Hypertriglyceridaemia | 119.42 | 14.01 | 96 | 65977 | 11109 | 64421550 |
Generalised tonic-clonic seizure | 119.20 | 14.01 | 174 | 65899 | 39683 | 64392976 |
Respiratory failure | 116.81 | 14.01 | 397 | 65676 | 160786 | 64271873 |
Weight decreased | 114.59 | 14.01 | 76 | 65997 | 285663 | 64146996 |
Vasoplegia syndrome | 110.96 | 14.01 | 55 | 66018 | 2712 | 64429947 |
Respiratory arrest | 110.09 | 14.01 | 196 | 65877 | 52789 | 64379870 |
Anticholinergic syndrome | 109.85 | 14.01 | 54 | 66019 | 2615 | 64430044 |
Pain | 109.79 | 14.01 | 254 | 65819 | 553257 | 63879402 |
Hypoxic-ischaemic encephalopathy | 109.14 | 14.01 | 76 | 65997 | 7076 | 64425583 |
Trigemino-cardiac reflex | 109.12 | 14.01 | 29 | 66044 | 215 | 64432444 |
Asthenia | 107.96 | 14.01 | 170 | 65903 | 427874 | 64004785 |
Opisthotonus | 107.20 | 14.01 | 36 | 66037 | 635 | 64432024 |
Brain oedema | 106.32 | 14.01 | 122 | 65951 | 21953 | 64410706 |
Unresponsive to stimuli | 105.46 | 14.01 | 187 | 65886 | 50206 | 64382453 |
Sinusitis | 104.88 | 14.01 | 13 | 66060 | 145915 | 64286744 |
Toxic epidermal necrolysis | 103.61 | 14.01 | 157 | 65916 | 37009 | 64395650 |
Drug reaction with eosinophilia and systemic symptoms | 101.84 | 14.01 | 192 | 65881 | 54025 | 64378634 |
Constipation | 101.79 | 14.01 | 54 | 66019 | 229283 | 64203376 |
Agitation | 100.86 | 14.01 | 256 | 65817 | 88111 | 64344548 |
Labile blood pressure | 100.55 | 14.01 | 47 | 66026 | 2033 | 64430626 |
Pulse absent | 100.38 | 14.01 | 79 | 65994 | 8867 | 64423792 |
Arthropathy | 99.86 | 14.01 | 6 | 66067 | 120961 | 64311698 |
Fear | 99.72 | 14.01 | 113 | 65960 | 20058 | 64412601 |
Death | 99.35 | 14.01 | 217 | 65856 | 482488 | 63950171 |
Anaesthetic complication pulmonary | 98.35 | 14.01 | 21 | 66052 | 49 | 64432610 |
PCO2 increased | 97.44 | 14.01 | 43 | 66030 | 1624 | 64431035 |
Muscle rigidity | 96.96 | 14.01 | 104 | 65969 | 17369 | 64415290 |
Acute respiratory distress syndrome | 96.75 | 14.01 | 156 | 65917 | 38779 | 64393880 |
Renal injury | 96.67 | 14.01 | 98 | 65975 | 15331 | 64417328 |
Erythema | 96.13 | 14.01 | 413 | 65660 | 186657 | 64246002 |
Myoglobin urine present | 95.63 | 14.01 | 32 | 66041 | 558 | 64432101 |
Dyskinesia | 94.06 | 14.01 | 155 | 65918 | 39233 | 64393426 |
Clonus | 93.82 | 14.01 | 65 | 66008 | 6002 | 64426657 |
Endotracheal intubation complication | 93.36 | 14.01 | 33 | 66040 | 683 | 64431976 |
Insomnia | 93.19 | 14.01 | 43 | 66030 | 197793 | 64234866 |
Tachypnoea | 92.84 | 14.01 | 125 | 65948 | 26446 | 64406213 |
Pruritus | 88.68 | 14.01 | 114 | 65959 | 312286 | 64120373 |
Abdominal pain | 88.66 | 14.01 | 114 | 65959 | 312261 | 64120398 |
Negative pressure pulmonary oedema | 87.52 | 14.01 | 24 | 66049 | 203 | 64432456 |
Contusion | 87.39 | 14.01 | 8 | 66065 | 113957 | 64318702 |
Urinary tract infection | 87.03 | 14.01 | 66 | 66007 | 231530 | 64201129 |
Pulmonary oedema | 86.75 | 14.01 | 225 | 65848 | 78449 | 64354210 |
Necrosis ischaemic | 86.68 | 14.01 | 34 | 66039 | 949 | 64431710 |
Sinus tachycardia | 85.54 | 14.01 | 133 | 65940 | 32055 | 64400604 |
Neutropenia | 85.39 | 14.01 | 72 | 66001 | 239552 | 64193107 |
Disseminated intravascular coagulation | 85.04 | 14.01 | 133 | 65940 | 32215 | 64400444 |
Kounis syndrome | 83.91 | 14.01 | 47 | 66026 | 2978 | 64429681 |
Neuromuscular blockade | 83.79 | 14.01 | 28 | 66045 | 486 | 64432173 |
Infusion related reaction | 83.47 | 14.01 | 32 | 66041 | 164435 | 64268224 |
Cardiogenic shock | 83.41 | 14.01 | 132 | 65941 | 32295 | 64400364 |
Mydriasis | 82.96 | 14.01 | 90 | 65983 | 15222 | 64417437 |
Neuropathy peripheral | 80.81 | 14.01 | 12 | 66061 | 117513 | 64315146 |
Multiple-drug resistance | 80.78 | 14.01 | 61 | 66012 | 6441 | 64426218 |
Influenza | 80.30 | 14.01 | 8 | 66065 | 106523 | 64326136 |
Anaemia | 78.86 | 14.01 | 169 | 65904 | 378511 | 64054148 |
Pneumonia | 78.25 | 14.01 | 302 | 65771 | 559274 | 63873385 |
Back pain | 77.69 | 14.01 | 85 | 65988 | 250086 | 64182573 |
Hepatorenal failure | 77.56 | 14.01 | 33 | 66040 | 1139 | 64431520 |
Injection site pain | 77.47 | 14.01 | 11 | 66062 | 111397 | 64321262 |
Oedema peripheral | 76.40 | 14.01 | 62 | 66011 | 210255 | 64222404 |
Laryngeal oedema | 75.92 | 14.01 | 61 | 66012 | 7052 | 64425607 |
Injury | 75.45 | 14.01 | 173 | 65900 | 55819 | 64376840 |
Therapeutic product effect prolonged | 75.28 | 14.01 | 26 | 66047 | 501 | 64432158 |
Anhedonia | 75.03 | 14.01 | 81 | 65992 | 13625 | 64419034 |
Bronchitis | 75.01 | 14.01 | 11 | 66062 | 108732 | 64323927 |
Blood lactic acid increased | 74.35 | 14.01 | 71 | 66002 | 10330 | 64422329 |
Oliguria | 74.34 | 14.01 | 83 | 65990 | 14493 | 64418166 |
Swelling | 73.64 | 14.01 | 36 | 66037 | 160182 | 64272477 |
Stomatitis | 73.52 | 14.01 | 12 | 66061 | 109593 | 64323066 |
Arthritis | 72.85 | 14.01 | 3 | 66070 | 83811 | 64348848 |
Post procedural haemorrhage | 72.53 | 14.01 | 76 | 65997 | 12355 | 64420304 |
Disease progression | 71.17 | 14.01 | 28 | 66045 | 141652 | 64291007 |
Seizure | 70.54 | 14.01 | 348 | 65725 | 166544 | 64266115 |
Malignant neoplasm progression | 70.07 | 14.01 | 15 | 66058 | 112856 | 64319803 |
Hypercapnia | 69.69 | 14.01 | 60 | 66013 | 7634 | 64425025 |
Electrocardiogram QT prolonged | 68.68 | 14.01 | 208 | 65865 | 79240 | 64353419 |
Abdominal pain upper | 68.18 | 14.01 | 48 | 66025 | 174982 | 64257677 |
Cyanosis | 68.09 | 14.01 | 98 | 65975 | 22057 | 64410602 |
Pulmonary alveolar haemorrhage | 66.82 | 14.01 | 65 | 66008 | 9673 | 64422986 |
Procedural haemorrhage | 66.80 | 14.01 | 46 | 66027 | 4206 | 64428453 |
Mitochondrial DNA mutation | 66.72 | 14.01 | 20 | 66053 | 239 | 64432420 |
Systemic lupus erythematosus | 66.72 | 14.01 | 3 | 66070 | 77609 | 64355050 |
Ventricular extrasystoles | 66.70 | 14.01 | 86 | 65987 | 17443 | 64415216 |
Gait disturbance | 66.02 | 14.01 | 48 | 66025 | 172107 | 64260552 |
Upper airway obstruction | 65.72 | 14.01 | 30 | 66043 | 1228 | 64431431 |
Suspected product quality issue | 65.61 | 14.01 | 20 | 66053 | 254 | 64432405 |
Ventricular arrhythmia | 65.49 | 14.01 | 57 | 66016 | 7358 | 64425301 |
Acute pulmonary oedema | 65.43 | 14.01 | 73 | 66000 | 12736 | 64419923 |
Cough | 65.27 | 14.01 | 132 | 65941 | 302016 | 64130643 |
Postoperative delirium | 65.15 | 14.01 | 18 | 66055 | 157 | 64432502 |
Coagulopathy | 64.91 | 14.01 | 117 | 65956 | 31803 | 64400856 |
Dehydration | 64.73 | 14.01 | 76 | 65997 | 216687 | 64215972 |
Chest pain | 63.99 | 14.01 | 89 | 65984 | 235891 | 64196768 |
Intra-abdominal pressure increased | 63.31 | 14.01 | 19 | 66054 | 228 | 64432431 |
Feeling abnormal | 62.95 | 14.01 | 29 | 66044 | 133573 | 64299086 |
Electroencephalogram abnormal | 62.84 | 14.01 | 48 | 66025 | 5155 | 64427504 |
Resuscitation | 62.76 | 14.01 | 34 | 66039 | 2017 | 64430642 |
Febrile neutropenia | 62.51 | 14.01 | 60 | 66013 | 187597 | 64245062 |
Delirium | 62.50 | 14.01 | 184 | 65889 | 69010 | 64363649 |
Inappropriate schedule of product administration | 62.13 | 14.01 | 10 | 66063 | 92276 | 64340383 |
Drug ineffective for unapproved indication | 61.89 | 14.01 | 113 | 65960 | 31020 | 64401639 |
Post procedural fever | 61.67 | 14.01 | 22 | 66051 | 468 | 64432191 |
Local anaesthetic systemic toxicity | 61.48 | 14.01 | 24 | 66049 | 661 | 64431998 |
Septic shock | 61.37 | 14.01 | 242 | 65831 | 105195 | 64327464 |
Acidosis | 61.07 | 14.01 | 83 | 65990 | 17712 | 64414947 |
Psoriasis | 60.90 | 14.01 | 3 | 66070 | 71700 | 64360959 |
Seizure like phenomena | 60.84 | 14.01 | 31 | 66042 | 1621 | 64431038 |
Spinal muscular atrophy | 60.05 | 14.01 | 19 | 66054 | 275 | 64432384 |
White blood cell count decreased | 59.24 | 14.01 | 45 | 66028 | 157792 | 64274867 |
Musculoskeletal stiffness | 59.21 | 14.01 | 26 | 66047 | 123180 | 64309479 |
Neuroleptic malignant syndrome | 59.18 | 14.01 | 98 | 65975 | 24898 | 64407761 |
Anaesthetic complication cardiac | 58.95 | 14.01 | 14 | 66059 | 61 | 64432598 |
Atrioventricular block complete | 58.44 | 14.01 | 73 | 66000 | 14345 | 64418314 |
Contraindicated product administered | 58.08 | 14.01 | 19 | 66054 | 107810 | 64324849 |
Renal impairment | 58.08 | 14.01 | 283 | 65790 | 134734 | 64297925 |
Recurrence of neuromuscular blockade | 57.99 | 14.01 | 17 | 66056 | 187 | 64432472 |
PO2 increased | 57.88 | 14.01 | 29 | 66044 | 1463 | 64431196 |
Acidosis hyperchloraemic | 57.74 | 14.01 | 23 | 66050 | 669 | 64431990 |
Stridor | 56.76 | 14.01 | 44 | 66029 | 4830 | 64427829 |
Electrocardiogram QRS complex prolonged | 54.80 | 14.01 | 57 | 66016 | 9187 | 64423472 |
Herpes zoster | 54.63 | 14.01 | 8 | 66065 | 79179 | 64353480 |
Endotracheal intubation | 53.91 | 14.01 | 39 | 66034 | 3856 | 64428803 |
Drug level changed | 53.85 | 14.01 | 20 | 66053 | 479 | 64432180 |
Ventricular hypokinesia | 53.58 | 14.01 | 52 | 66021 | 7717 | 64424942 |
Airway peak pressure increased | 53.52 | 14.01 | 18 | 66055 | 319 | 64432340 |
Dyspepsia | 53.40 | 14.01 | 9 | 66064 | 80303 | 64352356 |
Hyperammonaemia | 53.28 | 14.01 | 58 | 66015 | 9846 | 64422813 |
Syncope | 52.96 | 14.01 | 50 | 66023 | 157585 | 64275074 |
Carcinoid crisis | 51.96 | 14.01 | 19 | 66054 | 435 | 64432224 |
Muscle spasms | 51.91 | 14.01 | 41 | 66032 | 140982 | 64291677 |
Blood pH decreased | 51.83 | 14.01 | 40 | 66033 | 4362 | 64428297 |
Haemodialysis | 51.69 | 14.01 | 75 | 65998 | 17002 | 64415657 |
Skin test positive | 51.54 | 14.01 | 24 | 66049 | 1029 | 64431630 |
Hepatocellular injury | 51.53 | 14.01 | 131 | 65942 | 45104 | 64387555 |
Oculogyric crisis | 50.93 | 14.01 | 32 | 66041 | 2506 | 64430153 |
Renal ischaemia | 50.89 | 14.01 | 24 | 66049 | 1059 | 64431600 |
Loss of personal independence in daily activities | 50.73 | 14.01 | 7 | 66066 | 72447 | 64360212 |
Lactic acidosis | 50.48 | 14.01 | 158 | 65915 | 61252 | 64371407 |
Lower respiratory tract infection | 50.38 | 14.01 | 17 | 66056 | 94597 | 64338062 |
Subcutaneous emphysema | 50.15 | 14.01 | 27 | 66046 | 1582 | 64431077 |
Renal failure | 49.96 | 14.01 | 338 | 65735 | 181350 | 64251309 |
Oxygen saturation immeasurable | 49.77 | 14.01 | 11 | 66062 | 32 | 64432627 |
Gastrointestinal disorder | 49.75 | 14.01 | 15 | 66058 | 89694 | 64342965 |
Hyperreflexia | 49.59 | 14.01 | 48 | 66025 | 7100 | 64425559 |
Foetal death | 49.21 | 14.01 | 44 | 66029 | 5886 | 64426773 |
Urticaria | 49.18 | 14.01 | 288 | 65785 | 147029 | 64285630 |
Mucosal inflammation | 49.04 | 14.01 | 4 | 66069 | 62580 | 64370079 |
Hospitalisation | 48.75 | 14.01 | 9 | 66064 | 75198 | 64357461 |
Systemic inflammatory response syndrome | 48.32 | 14.01 | 56 | 66017 | 10179 | 64422480 |
Encephalopathy | 48.04 | 14.01 | 151 | 65922 | 58668 | 64373991 |
Discomfort | 47.70 | 14.01 | 12 | 66061 | 80866 | 64351793 |
Pneumatosis | 47.54 | 14.01 | 21 | 66052 | 795 | 64431864 |
Ischaemic cerebral infarction | 46.36 | 14.01 | 28 | 66045 | 2044 | 64430615 |
Brain injury | 46.18 | 14.01 | 54 | 66019 | 9911 | 64422748 |
Vomiting | 46.14 | 14.01 | 353 | 65720 | 550764 | 63881895 |
Hepatic ischaemia | 46.04 | 14.01 | 22 | 66051 | 1000 | 64431659 |
Suspected product contamination | 46 | 14.01 | 12 | 66061 | 82 | 64432577 |
Cardiac output decreased | 45.98 | 14.01 | 26 | 66047 | 1678 | 64430981 |
Wound | 45.78 | 14.01 | 11 | 66062 | 76466 | 64356193 |
Amylase increased | 45.74 | 14.01 | 53 | 66020 | 9632 | 64423027 |
End-tidal CO2 decreased | 45.53 | 14.01 | 10 | 66063 | 28 | 64432631 |
Autonomic nervous system imbalance | 45.30 | 14.01 | 36 | 66037 | 4096 | 64428563 |
Mean arterial pressure decreased | 45.18 | 14.01 | 16 | 66057 | 333 | 64432326 |
Product contamination | 45.10 | 14.01 | 22 | 66051 | 1047 | 64431612 |
Brugada syndrome | 44.93 | 14.01 | 22 | 66051 | 1056 | 64431603 |
Musculoskeletal pain | 44.35 | 14.01 | 14 | 66059 | 81280 | 64351379 |
Infection | 44.10 | 14.01 | 76 | 65997 | 184804 | 64247855 |
Emotional distress | 43.82 | 14.01 | 107 | 65966 | 35931 | 64396728 |
Nasal congestion | 43.62 | 14.01 | 5 | 66068 | 59653 | 64373006 |
Mental status changes postoperative | 43.55 | 14.01 | 13 | 66060 | 153 | 64432506 |
Balance disorder | 43.11 | 14.01 | 16 | 66057 | 83910 | 64348749 |
Sinus arrest | 42.90 | 14.01 | 31 | 66042 | 3059 | 64429600 |
Product contamination microbial | 42.83 | 14.01 | 20 | 66053 | 863 | 64431796 |
Injection site erythema | 42.74 | 14.01 | 10 | 66063 | 70790 | 64361869 |
Depression | 42.22 | 14.01 | 77 | 65996 | 183214 | 64249445 |
Brain death | 42.19 | 14.01 | 37 | 66036 | 4824 | 64427835 |
Macroglossia | 42.07 | 14.01 | 21 | 66052 | 1051 | 64431608 |
Cardiac failure congestive | 42.03 | 14.01 | 43 | 66030 | 130537 | 64302122 |
Acute kidney injury | 41.82 | 14.01 | 669 | 65404 | 448571 | 63984088 |
Exposure during pregnancy | 41.78 | 14.01 | 174 | 65899 | 77501 | 64355158 |
Unmasking of previously unidentified disease | 41.41 | 14.01 | 24 | 66049 | 1623 | 64431036 |
Electrocardiogram ST segment depression | 41.33 | 14.01 | 35 | 66038 | 4354 | 64428305 |
Diabetes mellitus | 40.91 | 14.01 | 9 | 66064 | 66465 | 64366194 |
Coma | 40.83 | 14.01 | 188 | 65885 | 87427 | 64345232 |
Blood gases abnormal | 40.79 | 14.01 | 20 | 66053 | 963 | 64431696 |
Blood pressure immeasurable | 40.68 | 14.01 | 25 | 66048 | 1883 | 64430776 |
Hypocapnia | 40.33 | 14.01 | 17 | 66056 | 573 | 64432086 |
Hypoaesthesia | 40.20 | 14.01 | 50 | 66023 | 139058 | 64293601 |
Chromaturia | 39.89 | 14.01 | 78 | 65995 | 22533 | 64410126 |
Aspiration | 39.70 | 14.01 | 66 | 66007 | 16819 | 64415840 |
Wrong product administered | 39.43 | 14.01 | 44 | 66029 | 7676 | 64424983 |
Hepatitis acute | 39.36 | 14.01 | 58 | 66015 | 13331 | 64419328 |
Pseudocholinesterase deficiency | 39.32 | 14.01 | 12 | 66061 | 153 | 64432506 |
Gastrooesophageal reflux disease | 39.23 | 14.01 | 18 | 66055 | 83125 | 64349534 |
Sinus bradycardia | 39.21 | 14.01 | 78 | 65995 | 22815 | 64409844 |
Air embolism | 38.98 | 14.01 | 15 | 66058 | 397 | 64432262 |
Left ventricle outflow tract obstruction | 38.93 | 14.01 | 14 | 66059 | 305 | 64432354 |
Oxygen saturation abnormal | 38.91 | 14.01 | 31 | 66042 | 3540 | 64429119 |
Unevaluable event | 38.85 | 14.01 | 127 | 65946 | 50362 | 64382297 |
Respiratory distress | 38.81 | 14.01 | 130 | 65943 | 52201 | 64380458 |
Muscle relaxant therapy | 38.56 | 14.01 | 12 | 66061 | 164 | 64432495 |
Skin test negative | 38.52 | 14.01 | 9 | 66064 | 36 | 64432623 |
Thyrotoxic crisis | 38.38 | 14.01 | 20 | 66053 | 1096 | 64431563 |
Respiratory tract infection bacterial | 37.94 | 14.01 | 18 | 66055 | 805 | 64431854 |
Hyperkalaemia | 37.91 | 14.01 | 204 | 65869 | 100925 | 64331734 |
Angioedema | 37.67 | 14.01 | 144 | 65929 | 61677 | 64370982 |
Palpitations | 37.67 | 14.01 | 31 | 66042 | 104457 | 64328202 |
Acute postoperative sialadenitis | 37.22 | 14.01 | 9 | 66064 | 43 | 64432616 |
Hepatitis | 37.20 | 14.01 | 117 | 65956 | 45465 | 64387194 |
Hepatic failure | 37.08 | 14.01 | 133 | 65940 | 55261 | 64377398 |
Pancytopenia | 36.90 | 14.01 | 56 | 66017 | 143253 | 64289406 |
Confusion postoperative | 36.70 | 14.01 | 12 | 66061 | 194 | 64432465 |
Long QT syndrome | 36.57 | 14.01 | 35 | 66038 | 5104 | 64427555 |
Hypotonia | 36.53 | 14.01 | 51 | 66022 | 11161 | 64421498 |
Procedural hypertension | 36.38 | 14.01 | 13 | 66060 | 278 | 64432381 |
Eosinophilia | 36.05 | 14.01 | 103 | 65970 | 37973 | 64394686 |
Increased bronchial secretion | 36.05 | 14.01 | 27 | 66046 | 2815 | 64429844 |
Intracranial pressure increased | 35.99 | 14.01 | 40 | 66033 | 6949 | 64425710 |
Blood pressure measurement | 35.99 | 14.01 | 14 | 66059 | 382 | 64432277 |
Hepatitis fulminant | 35.96 | 14.01 | 38 | 66035 | 6236 | 64426423 |
Asthma | 35.91 | 14.01 | 27 | 66046 | 95198 | 64337461 |
Nodal rhythm | 35.78 | 14.01 | 27 | 66046 | 2847 | 64429812 |
Chronic obstructive pulmonary disease | 35.73 | 14.01 | 14 | 66059 | 71034 | 64361625 |
Dry mouth | 35.56 | 14.01 | 9 | 66064 | 60409 | 64372250 |
Mobility decreased | 35.49 | 14.01 | 22 | 66051 | 85818 | 64346841 |
Chest discomfort | 35.40 | 14.01 | 40 | 66033 | 116066 | 64316593 |
Post-injection delirium sedation syndrome | 35.38 | 14.01 | 15 | 66058 | 513 | 64432146 |
Arrhythmia | 35.33 | 14.01 | 127 | 65946 | 52817 | 64379842 |
Perforation | 35.04 | 14.01 | 19 | 66054 | 1129 | 64431530 |
Rash maculo-papular | 35.03 | 14.01 | 117 | 65956 | 46909 | 64385750 |
Incorrect drug administration rate | 34.87 | 14.01 | 26 | 66047 | 2693 | 64429966 |
Tonic clonic movements | 34.79 | 14.01 | 23 | 66050 | 1966 | 64430693 |
Dyspnoea exertional | 34.73 | 14.01 | 16 | 66057 | 73714 | 64358945 |
Hypernatraemia | 34.68 | 14.01 | 52 | 66021 | 12137 | 64420522 |
Neck pain | 34.65 | 14.01 | 10 | 66063 | 61523 | 64371136 |
Myoglobin blood increased | 34.63 | 14.01 | 26 | 66047 | 2721 | 64429938 |
Myoglobinuria | 34.62 | 14.01 | 18 | 66055 | 982 | 64431677 |
Therapeutic product effect incomplete | 34.54 | 14.01 | 33 | 66040 | 103449 | 64329210 |
Hepatic cytolysis | 34.49 | 14.01 | 56 | 66017 | 13993 | 64418666 |
Acute generalised exanthematous pustulosis | 34.47 | 14.01 | 56 | 66017 | 14002 | 64418657 |
Oculocardiac reflex | 34.44 | 14.01 | 9 | 66064 | 62 | 64432597 |
Hyperthermia | 34.20 | 14.01 | 59 | 66014 | 15491 | 64417168 |
Spinal cord infarction | 34.18 | 14.01 | 15 | 66058 | 559 | 64432100 |
Upper respiratory tract infection | 33.96 | 14.01 | 16 | 66057 | 72769 | 64359890 |
Gene mutation | 33.83 | 14.01 | 23 | 66050 | 2059 | 64430600 |
Suicidal ideation | 33.65 | 14.01 | 13 | 66060 | 66529 | 64366130 |
Transcranial electrical motor evoked potential monitoring abnormal | 33.52 | 14.01 | 7 | 66066 | 14 | 64432645 |
Hepatorenal syndrome | 33.50 | 14.01 | 29 | 66044 | 3717 | 64428942 |
Plasma cell myeloma | 33.34 | 14.01 | 4 | 66069 | 46071 | 64386588 |
Symmetrical drug-related intertriginous and flexural exanthema | 33.04 | 14.01 | 15 | 66058 | 606 | 64432053 |
Premature recovery from anaesthesia | 32.88 | 14.01 | 6 | 66067 | 3 | 64432656 |
Partial seizures | 32.87 | 14.01 | 39 | 66034 | 7268 | 64425391 |
Laryngeal stenosis | 32.24 | 14.01 | 16 | 66057 | 791 | 64431868 |
Ultrasound ovary abnormal | 31.75 | 14.01 | 9 | 66064 | 87 | 64432572 |
Myotonia | 31.61 | 14.01 | 11 | 66062 | 217 | 64432442 |
Rhinorrhoea | 31.53 | 14.01 | 11 | 66062 | 59958 | 64372701 |
Drug ineffective | 31.48 | 14.01 | 1102 | 64971 | 839145 | 63593514 |
Premature delivery | 31.43 | 14.01 | 63 | 66010 | 18526 | 64414133 |
Systolic anterior motion of mitral valve | 31.42 | 14.01 | 8 | 66065 | 49 | 64432610 |
Atrioventricular dissociation | 31.35 | 14.01 | 12 | 66061 | 313 | 64432346 |
Dry skin | 31.33 | 14.01 | 7 | 66066 | 51154 | 64381505 |
Fluid retention | 31.23 | 14.01 | 11 | 66062 | 59595 | 64373064 |
Neoplasm progression | 31.06 | 14.01 | 3 | 66070 | 40961 | 64391698 |
Paralysis | 30.92 | 14.01 | 48 | 66025 | 11547 | 64421112 |
Hypothermia | 30.87 | 14.01 | 65 | 66008 | 19791 | 64412868 |
Maternal exposure during delivery | 30.75 | 14.01 | 16 | 66057 | 874 | 64431785 |
Obstructive airways disorder | 30.52 | 14.01 | 71 | 66002 | 23114 | 64409545 |
Depressed level of consciousness | 30.33 | 14.01 | 164 | 65909 | 81272 | 64351387 |
Impaired healing | 30.27 | 14.01 | 12 | 66061 | 60461 | 64372198 |
Cystitis | 30.16 | 14.01 | 4 | 66069 | 42671 | 64389988 |
Pneumococcal sepsis | 30.15 | 14.01 | 18 | 66055 | 1286 | 64431373 |
Haemoglobin decreased | 29.98 | 14.01 | 101 | 65972 | 194962 | 64237697 |
General physical health deterioration | 29.98 | 14.01 | 108 | 65965 | 204317 | 64228342 |
Areflexia | 29.90 | 14.01 | 31 | 66042 | 4976 | 64427683 |
Metabolic disorder | 29.65 | 14.01 | 38 | 66035 | 7659 | 64425000 |
Post procedural hypotension | 29.57 | 14.01 | 8 | 66065 | 64 | 64432595 |
Electrocardiogram ST-T segment elevation | 29.42 | 14.01 | 5 | 66068 | 0 | 64432659 |
Bispectral index decreased | 29.42 | 14.01 | 5 | 66068 | 0 | 64432659 |
Hypovolaemia | 29.26 | 14.01 | 55 | 66018 | 15431 | 64417228 |
Nystagmus | 29.17 | 14.01 | 41 | 66032 | 9027 | 64423632 |
Pneumomediastinum | 29.12 | 14.01 | 24 | 66049 | 2876 | 64429783 |
Vertigo | 29.07 | 14.01 | 12 | 66061 | 58999 | 64373660 |
Neutrophil count decreased | 28.96 | 14.01 | 22 | 66051 | 77174 | 64355485 |
Hyperlactacidaemia | 28.95 | 14.01 | 30 | 66043 | 4814 | 64427845 |
Oropharyngeal pain | 28.89 | 14.01 | 29 | 66044 | 88838 | 64343821 |
Treatment failure | 28.78 | 14.01 | 47 | 66026 | 116769 | 64315890 |
Depressed mood | 28.62 | 14.01 | 4 | 66069 | 41008 | 64391651 |
Ventricular dysfunction | 28.59 | 14.01 | 31 | 66042 | 5239 | 64427420 |
Supraventricular tachycardia | 28.36 | 14.01 | 61 | 66012 | 18846 | 64413813 |
Hyperventilation | 28.31 | 14.01 | 35 | 66038 | 6805 | 64425854 |
Priapism | 28.18 | 14.01 | 27 | 66046 | 3943 | 64428716 |
Bone pain | 28.16 | 14.01 | 7 | 66066 | 47565 | 64385094 |
Paraesthesia | 27.96 | 14.01 | 60 | 66013 | 134462 | 64298197 |
Maternal exposure during pregnancy | 27.91 | 14.01 | 181 | 65892 | 95703 | 64336956 |
Apnoeic attack | 27.90 | 14.01 | 13 | 66060 | 558 | 64432101 |
Phrenic nerve paralysis | 27.80 | 14.01 | 10 | 66063 | 218 | 64432441 |
Burkholderia test positive | 27.73 | 14.01 | 13 | 66060 | 566 | 64432093 |
Irritable bowel syndrome | 27.65 | 14.01 | 3 | 66070 | 37366 | 64395293 |
Epistaxis | 27.59 | 14.01 | 36 | 66037 | 98095 | 64334564 |
End-tidal CO2 increased | 27.53 | 14.01 | 6 | 66067 | 16 | 64432643 |
Gaze palsy | 27.49 | 14.01 | 22 | 66051 | 2528 | 64430131 |
Coma blister | 27.47 | 14.01 | 10 | 66063 | 226 | 64432433 |
Extrasystoles | 27.45 | 14.01 | 34 | 66039 | 6624 | 64426035 |
Eye movement disorder | 27.35 | 14.01 | 35 | 66038 | 7044 | 64425615 |
Pneumothorax | 27.29 | 14.01 | 70 | 66003 | 24228 | 64408431 |
Acute hepatic failure | 27.05 | 14.01 | 73 | 66000 | 26039 | 64406620 |
Muscle twitching | 27.03 | 14.01 | 60 | 66013 | 18938 | 64413721 |
Troponin increased | 27.02 | 14.01 | 53 | 66020 | 15346 | 64417313 |
Tongue oedema | 26.99 | 14.01 | 32 | 66041 | 5958 | 64426701 |
Posterior reversible encephalopathy syndrome | 26.70 | 14.01 | 67 | 66006 | 22879 | 64409780 |
Alanine aminotransferase increased | 26.70 | 14.01 | 238 | 65835 | 138793 | 64293866 |
Atrioventricular block first degree | 26.64 | 14.01 | 43 | 66030 | 10691 | 64421968 |
Myalgia | 26.57 | 14.01 | 79 | 65994 | 158538 | 64274121 |
Locked-in syndrome | 26.57 | 14.01 | 13 | 66060 | 623 | 64432036 |
Multiple sclerosis relapse | 26.49 | 14.01 | 5 | 66068 | 41130 | 64391529 |
Atelectasis | 26.05 | 14.01 | 74 | 65999 | 27192 | 64405467 |
Migraine | 25.99 | 14.01 | 16 | 66057 | 62661 | 64369998 |
Fibrinolysis | 25.98 | 14.01 | 7 | 66066 | 55 | 64432604 |
Cellulitis | 25.68 | 14.01 | 35 | 66038 | 93622 | 64339037 |
Chemical peritonitis | 25.66 | 14.01 | 10 | 66063 | 274 | 64432385 |
Blood pressure systolic decreased | 25.63 | 14.01 | 38 | 66035 | 8782 | 64423877 |
Procedural nausea | 25.49 | 14.01 | 13 | 66060 | 681 | 64431978 |
Blood bicarbonate decreased | 25.49 | 14.01 | 28 | 66045 | 4801 | 64427858 |
Hyponatraemia | 25.49 | 14.01 | 73 | 66000 | 148266 | 64284393 |
Extravasation | 25.21 | 14.01 | 23 | 66050 | 3157 | 64429502 |
Transient ischaemic attack | 25.21 | 14.01 | 7 | 66066 | 44175 | 64388484 |
Hot flush | 25.15 | 14.01 | 8 | 66065 | 46227 | 64386432 |
Atrioventricular block second degree | 25.08 | 14.01 | 32 | 66041 | 6422 | 64426237 |
Cardiovascular insufficiency | 24.86 | 14.01 | 21 | 66052 | 2603 | 64430056 |
Respiratory alkalosis | 24.86 | 14.01 | 25 | 66048 | 3872 | 64428787 |
Coma scale abnormal | 24.79 | 14.01 | 35 | 66038 | 7739 | 64424920 |
Completed suicide | 24.73 | 14.01 | 132 | 65941 | 224282 | 64208377 |
Dialysis | 24.71 | 14.01 | 54 | 66019 | 16866 | 64415793 |
Burning sensation | 24.62 | 14.01 | 10 | 66063 | 49654 | 64383005 |
Motor neurone disease | 24.62 | 14.01 | 11 | 66062 | 428 | 64432231 |
Mechanical ventilation | 24.55 | 14.01 | 20 | 66053 | 2358 | 64430301 |
Stoma closure | 24.49 | 14.01 | 8 | 66065 | 129 | 64432530 |
Hypoglycaemia | 24.24 | 14.01 | 34 | 66039 | 89858 | 64342801 |
Polyuria | 24.00 | 14.01 | 45 | 66028 | 12598 | 64420061 |
Toxic encephalopathy | 23.93 | 14.01 | 39 | 66034 | 9776 | 64422883 |
Heparin-induced thrombocytopenia | 23.88 | 14.01 | 36 | 66037 | 8443 | 64424216 |
Productive cough | 23.67 | 14.01 | 24 | 66049 | 73179 | 64359480 |
Therapeutic response prolonged | 23.54 | 14.01 | 4 | 66069 | 0 | 64432659 |
Haematochezia | 23.54 | 14.01 | 20 | 66053 | 66353 | 64366306 |
Vision blurred | 23.52 | 14.01 | 35 | 66038 | 90281 | 64342378 |
Motor dysfunction | 23.52 | 14.01 | 42 | 66031 | 11331 | 64421328 |
Osteoporosis | 23.39 | 14.01 | 7 | 66066 | 42073 | 64390586 |
Rash pruritic | 23.33 | 14.01 | 15 | 66058 | 57389 | 64375270 |
Osteonecrosis of jaw | 23.31 | 14.01 | 6 | 66067 | 39819 | 64392840 |
Throat irritation | 23.28 | 14.01 | 3 | 66070 | 32708 | 64399951 |
Superinfection | 23.10 | 14.01 | 24 | 66049 | 3862 | 64428797 |
Nephrolithiasis | 22.99 | 14.01 | 8 | 66065 | 43675 | 64388984 |
Pupil fixed | 22.98 | 14.01 | 22 | 66051 | 3210 | 64429449 |
Procedural vomiting | 22.96 | 14.01 | 12 | 66061 | 662 | 64431997 |
Vitamin K deficiency | 22.87 | 14.01 | 12 | 66061 | 667 | 64431992 |
Myxoedema coma | 22.74 | 14.01 | 12 | 66061 | 675 | 64431984 |
Shock haemorrhagic | 22.74 | 14.01 | 52 | 66021 | 16739 | 64415920 |
Face oedema | 22.49 | 14.01 | 66 | 66007 | 24695 | 64407964 |
Hyperammonaemic encephalopathy | 22.24 | 14.01 | 24 | 66049 | 4034 | 64428625 |
Lymphadenopathy | 22.19 | 14.01 | 10 | 66063 | 46676 | 64385983 |
Clonic convulsion | 22.18 | 14.01 | 14 | 66059 | 1105 | 64431554 |
Myoclonic epilepsy | 22.03 | 14.01 | 16 | 66057 | 1592 | 64431067 |
Chills | 21.91 | 14.01 | 226 | 65847 | 137038 | 64295621 |
Oesophageal intramural haematoma | 21.89 | 14.01 | 7 | 66066 | 105 | 64432554 |
Atrioventricular block | 21.87 | 14.01 | 42 | 66031 | 11973 | 64420686 |
Coronary artery embolism | 21.82 | 14.01 | 9 | 66064 | 287 | 64432372 |
C-reactive protein increased | 21.72 | 14.01 | 40 | 66033 | 94869 | 64337790 |
Irregular breathing | 21.64 | 14.01 | 10 | 66063 | 421 | 64432238 |
Ill-defined disorder | 21.63 | 14.01 | 9 | 66064 | 44043 | 64388616 |
Extrapyramidal disorder | 21.62 | 14.01 | 56 | 66017 | 19496 | 64413163 |
Cardiac massage | 21.60 | 14.01 | 5 | 66068 | 19 | 64432640 |
Continuous haemodiafiltration | 21.40 | 14.01 | 17 | 66056 | 1933 | 64430726 |
Abdominal compartment syndrome | 21.38 | 14.01 | 15 | 66058 | 1413 | 64431246 |
Disease complication | 21.30 | 14.01 | 24 | 66049 | 4231 | 64428428 |
Joint stiffness | 21.13 | 14.01 | 3 | 66070 | 30401 | 64402258 |
Tracheal injury | 21.07 | 14.01 | 6 | 66067 | 59 | 64432600 |
Dysgeusia | 20.96 | 14.01 | 11 | 66062 | 47036 | 64385623 |
Aspartate aminotransferase increased | 20.95 | 14.01 | 201 | 65872 | 119587 | 64313072 |
Angina pectoris | 20.89 | 14.01 | 10 | 66063 | 45071 | 64387588 |
Cerebral ischaemia | 20.87 | 14.01 | 37 | 66036 | 9925 | 64422734 |
Bezold-Jarisch reflex | 20.83 | 14.01 | 5 | 66068 | 23 | 64432636 |
Drug withdrawal syndrome | 20.82 | 14.01 | 75 | 65998 | 31216 | 64401443 |
Sputum increased | 20.81 | 14.01 | 22 | 66051 | 3613 | 64429046 |
Orthostatic hypotension | 20.71 | 14.01 | 11 | 66062 | 46727 | 64385932 |
Prinzmetal angina | 20.69 | 14.01 | 15 | 66058 | 1488 | 64431171 |
Pneumonia staphylococcal | 20.62 | 14.01 | 24 | 66049 | 4382 | 64428277 |
Tracheal deviation | 20.47 | 14.01 | 6 | 66067 | 66 | 64432593 |
Sepsis syndrome | 20.46 | 14.01 | 14 | 66059 | 1267 | 64431392 |
Femur fracture | 20.25 | 14.01 | 5 | 66068 | 34130 | 64398529 |
Potentiating drug interaction | 20.24 | 14.01 | 32 | 66041 | 7820 | 64424839 |
Cardiovascular disorder | 20.21 | 14.01 | 48 | 66025 | 15833 | 64416826 |
Trismus | 20.16 | 14.01 | 25 | 66048 | 4876 | 64427783 |
Haemodilution | 20.07 | 14.01 | 7 | 66066 | 139 | 64432520 |
Eyelid oedema | 20.03 | 14.01 | 41 | 66032 | 12238 | 64420421 |
Fear of death | 20.01 | 14.01 | 14 | 66059 | 1313 | 64431346 |
Skin ulcer | 20.01 | 14.01 | 10 | 66063 | 43964 | 64388695 |
Hypotensive transfusion reaction | 19.99 | 14.01 | 6 | 66067 | 72 | 64432587 |
Agitation postoperative | 19.77 | 14.01 | 6 | 66067 | 75 | 64432584 |
Malignant catatonia | 19.72 | 14.01 | 9 | 66064 | 368 | 64432291 |
Myocardial infarction | 19.70 | 14.01 | 95 | 65978 | 165726 | 64266933 |
Palmar-plantar erythrodysaesthesia syndrome | 19.67 | 14.01 | 3 | 66070 | 28816 | 64403843 |
Blood catecholamines increased | 19.59 | 14.01 | 5 | 66068 | 31 | 64432628 |
Transaminases increased | 19.53 | 14.01 | 94 | 65979 | 44500 | 64388159 |
Fat embolism | 19.50 | 14.01 | 9 | 66064 | 378 | 64432281 |
Basal cell carcinoma | 19.33 | 14.01 | 4 | 66069 | 30834 | 64401825 |
Condition aggravated | 19.32 | 14.01 | 267 | 65806 | 372159 | 64060500 |
Injection site reaction | 19.23 | 14.01 | 12 | 66061 | 46652 | 64386007 |
Mechanical ventilation complication | 19.19 | 14.01 | 5 | 66068 | 34 | 64432625 |
Incorrect route of product administration | 19.19 | 14.01 | 60 | 66013 | 23238 | 64409421 |
Blood pressure fluctuation | 19.18 | 14.01 | 15 | 66058 | 51856 | 64380803 |
Rectal haemorrhage | 19.16 | 14.01 | 21 | 66052 | 61796 | 64370863 |
Histamine level increased | 19.15 | 14.01 | 6 | 66067 | 84 | 64432575 |
Pain in jaw | 18.95 | 14.01 | 9 | 66064 | 40746 | 64391913 |
Mucosal ulceration | 18.83 | 14.01 | 15 | 66058 | 1712 | 64430947 |
Sleep disorder | 18.82 | 14.01 | 20 | 66053 | 59689 | 64372970 |
Brain herniation | 18.77 | 14.01 | 28 | 66045 | 6505 | 64426154 |
Gait inability | 18.73 | 14.01 | 10 | 66063 | 42358 | 64390301 |
Chronic kidney disease | 18.71 | 14.01 | 19 | 66054 | 57900 | 64374759 |
Phaeochromocytoma | 18.68 | 14.01 | 10 | 66063 | 579 | 64432080 |
Product quality issue | 18.63 | 14.01 | 70 | 66003 | 29729 | 64402930 |
Electrocardiogram T wave inversion | 18.60 | 14.01 | 24 | 66049 | 4870 | 64427789 |
Electrocardiogram abnormal | 18.53 | 14.01 | 42 | 66031 | 13439 | 64419220 |
Idiopathic interstitial pneumonia | 18.35 | 14.01 | 7 | 66066 | 181 | 64432478 |
Inadequate aseptic technique in use of product | 18.29 | 14.01 | 6 | 66067 | 98 | 64432561 |
Night sweats | 18.29 | 14.01 | 7 | 66066 | 36039 | 64396620 |
Haematuria traumatic | 18.27 | 14.01 | 7 | 66066 | 183 | 64432476 |
Left ventricular dysfunction | 18.17 | 14.01 | 48 | 66025 | 16906 | 64415753 |
Altered state of consciousness | 18.14 | 14.01 | 82 | 65991 | 37820 | 64394839 |
Glossoptosis | 18.13 | 14.01 | 7 | 66066 | 187 | 64432472 |
Amaurosis | 18.08 | 14.01 | 12 | 66061 | 1032 | 64431627 |
Visual impairment | 18.06 | 14.01 | 30 | 66043 | 74047 | 64358612 |
Fibromyalgia | 18.03 | 14.01 | 7 | 66066 | 35724 | 64396935 |
Intensive care unit delirium | 17.96 | 14.01 | 5 | 66068 | 45 | 64432614 |
Capillary nail refill test abnormal | 17.76 | 14.01 | 5 | 66068 | 47 | 64432612 |
Intentional self-injury | 17.73 | 14.01 | 4 | 66069 | 29040 | 64403619 |
Tonic convulsion | 17.71 | 14.01 | 15 | 66058 | 1866 | 64430793 |
Dry eye | 17.71 | 14.01 | 4 | 66069 | 29015 | 64403644 |
Electrocardiogram repolarisation abnormality | 17.70 | 14.01 | 15 | 66058 | 1867 | 64430792 |
Laryngeal obstruction | 17.70 | 14.01 | 6 | 66067 | 109 | 64432550 |
Tryptase | 17.65 | 14.01 | 3 | 66070 | 0 | 64432659 |
Bone marrow failure | 17.56 | 14.01 | 14 | 66059 | 47938 | 64384721 |
Presyncope | 17.50 | 14.01 | 7 | 66066 | 35082 | 64397577 |
Acquired macroglossia | 17.50 | 14.01 | 7 | 66066 | 206 | 64432453 |
Lower respiratory tract infection bacterial | 17.42 | 14.01 | 10 | 66063 | 664 | 64431995 |
Malabsorption | 17.38 | 14.01 | 22 | 66051 | 4381 | 64428278 |
Nerve stimulation test abnormal | 17.32 | 14.01 | 4 | 66069 | 15 | 64432644 |
Postoperative respiratory distress | 17.32 | 14.01 | 4 | 66069 | 15 | 64432644 |
Neurological decompensation | 17.24 | 14.01 | 22 | 66051 | 4414 | 64428245 |
Euthanasia | 17.22 | 14.01 | 5 | 66068 | 53 | 64432606 |
Pancreatitis | 17.02 | 14.01 | 112 | 65961 | 59495 | 64373164 |
Blood triglycerides increased | 16.86 | 14.01 | 50 | 66023 | 18816 | 64413843 |
Sputum retention | 16.79 | 14.01 | 11 | 66062 | 926 | 64431733 |
Conversion disorder | 16.79 | 14.01 | 14 | 66059 | 1705 | 64430954 |
Cerebral hypoperfusion | 16.76 | 14.01 | 10 | 66063 | 714 | 64431945 |
Euthyroid sick syndrome | 16.74 | 14.01 | 5 | 66068 | 59 | 64432600 |
Red blood cell count decreased | 16.65 | 14.01 | 15 | 66058 | 48371 | 64384288 |
Symptom masked | 16.54 | 14.01 | 12 | 66061 | 1192 | 64431467 |
Supraventricular extrasystoles | 16.49 | 14.01 | 25 | 66048 | 5890 | 64426769 |
Adverse event | 16.48 | 14.01 | 10 | 66063 | 39479 | 64393180 |
Muscle necrosis | 16.37 | 14.01 | 12 | 66061 | 1211 | 64431448 |
Memory impairment | 16.36 | 14.01 | 40 | 66033 | 85642 | 64347017 |
Acute myeloid leukaemia | 16.34 | 14.01 | 4 | 66069 | 27459 | 64405200 |
Blood glucose increased | 16.30 | 14.01 | 49 | 66024 | 98024 | 64334635 |
Respiratory tract infection | 16.29 | 14.01 | 9 | 66064 | 37398 | 64395261 |
Product use issue | 16.28 | 14.01 | 90 | 65983 | 151625 | 64281034 |
Extubation | 16.07 | 14.01 | 4 | 66069 | 22 | 64432637 |
Hemiplegic migraine | 15.96 | 14.01 | 5 | 66068 | 70 | 64432589 |
Central-alveolar hypoventilation | 15.78 | 14.01 | 4 | 66069 | 24 | 64432635 |
Blood bilirubin increased | 15.75 | 14.01 | 107 | 65966 | 57446 | 64375213 |
Non-cardiogenic pulmonary oedema | 15.65 | 14.01 | 12 | 66061 | 1296 | 64431363 |
Chest X-ray abnormal | 15.55 | 14.01 | 26 | 66047 | 6655 | 64426004 |
Injection site haemorrhage | 15.53 | 14.01 | 3 | 66070 | 24275 | 64408384 |
Weaning failure | 15.42 | 14.01 | 9 | 66064 | 617 | 64432042 |
COVID-19 treatment | 15.34 | 14.01 | 8 | 66065 | 439 | 64432220 |
Documented hypersensitivity to administered product | 15.30 | 14.01 | 10 | 66063 | 838 | 64431821 |
Hypovolaemic shock | 15.26 | 14.01 | 33 | 66040 | 10233 | 64422426 |
Injection site swelling | 15.23 | 14.01 | 12 | 66061 | 41341 | 64391318 |
Neuralgia | 15.22 | 14.01 | 4 | 66069 | 26180 | 64406479 |
Osteoarthritis | 15.12 | 14.01 | 26 | 66047 | 63310 | 64369349 |
Light anaesthesia | 15.12 | 14.01 | 3 | 66070 | 4 | 64432655 |
Product administered to patient of inappropriate age | 15.09 | 14.01 | 21 | 66052 | 4580 | 64428079 |
Eyelid function disorder | 14.99 | 14.01 | 7 | 66066 | 302 | 64432357 |
Acute respiratory failure | 14.98 | 14.01 | 95 | 65978 | 49839 | 64382820 |
Gastritis | 14.92 | 14.01 | 13 | 66060 | 42605 | 64390054 |
Somatosensory evoked potentials abnormal | 14.86 | 14.01 | 6 | 66067 | 181 | 64432478 |
Decerebrate posture | 14.86 | 14.01 | 6 | 66067 | 181 | 64432478 |
Limb injury | 14.83 | 14.01 | 3 | 66070 | 23502 | 64409157 |
Myocardial stunning | 14.83 | 14.01 | 6 | 66067 | 182 | 64432477 |
Mutism | 14.75 | 14.01 | 14 | 66059 | 2020 | 64430639 |
Cytomegalovirus infection | 14.74 | 14.01 | 10 | 66063 | 37189 | 64395470 |
Ammonia increased | 14.73 | 14.01 | 26 | 66047 | 6951 | 64425708 |
Leukocytosis | 14.72 | 14.01 | 77 | 65996 | 37663 | 64394996 |
Gastroenteritis | 14.70 | 14.01 | 6 | 66067 | 29705 | 64402954 |
Device programming error | 14.64 | 14.01 | 5 | 66068 | 93 | 64432566 |
Hepatic enzyme increased | 14.54 | 14.01 | 76 | 65997 | 129867 | 64302792 |
Lipoedema | 14.53 | 14.01 | 6 | 66067 | 192 | 64432467 |
Blood glucose decreased | 14.49 | 14.01 | 3 | 66070 | 23120 | 64409539 |
Leukopenia | 14.49 | 14.01 | 54 | 66019 | 101188 | 64331471 |
Acne | 14.45 | 14.01 | 3 | 66070 | 23078 | 64409581 |
Bone cement implantation syndrome | 14.36 | 14.01 | 3 | 66070 | 6 | 64432653 |
Athetosis | 14.30 | 14.01 | 5 | 66068 | 100 | 64432559 |
Bronchial disorder | 14.29 | 14.01 | 14 | 66059 | 2101 | 64430558 |
Gastric disorder | 14.28 | 14.01 | 6 | 66067 | 29191 | 64403468 |
Pancreatitis necrotising | 14.19 | 14.01 | 17 | 66056 | 3200 | 64429459 |
Bundle branch block right | 14.12 | 14.01 | 32 | 66041 | 10237 | 64422422 |
Bradycardia foetal | 14.12 | 14.01 | 5 | 66068 | 104 | 64432555 |
Arrhythmia supraventricular | 14.03 | 14.01 | 13 | 66060 | 1820 | 64430839 |
Cerebrovascular accident | 14.02 | 14.01 | 83 | 65990 | 137500 | 64295159 |
None
Source | Code | Description |
---|---|---|
ATC | N01AX10 | NERVOUS SYSTEM ANESTHETICS ANESTHETICS, GENERAL Other general anesthetics |
FDA EPC | N0000175681 | General Anesthetic |
FDA PE | N0000175975 | General Anesthesia |
CHEBI has role | CHEBI:35623 | anticonvulsants |
CHEBI has role | CHEBI:35717 | hypnotics |
CHEBI has role | CHEBI:38877 | intravenous anesthetics |
CHEBI has role | CHEBI:48578 | free radical scavengers |
CHEBI has role | CHEBI:50919 | antiemetico |
MeSH PA | D000777 | Anesthetics |
MeSH PA | D018686 | Anesthetics, Intravenous |
MeSH PA | D002491 | Central Nervous System Agents |
MeSH PA | D002492 | Central Nervous System Depressants |
MeSH PA | D006993 | Hypnotics and Sedatives |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
General anesthesia | indication | 50697003 | |
Sedation in Intubated Patients | indication | ||
Sedation as Adjunct to Anesthesia | indication | ||
Apnea | contraindication | 1023001 | |
Asthenia | contraindication | 13791008 | |
Hypovolemia | contraindication | 28560003 | |
Low blood pressure | contraindication | 45007003 | |
Cerebral arteriosclerosis | contraindication | 65312002 | |
Decreased respiratory function | contraindication | 80954004 | |
Epilepsy | contraindication | 84757009 | DOID:1826 |
Myocardial dysfunction | contraindication | 233928007 | |
Disorder of lipid metabolism | contraindication | 267431006 | |
Hypoxia | contraindication | 389086002 |
Species | Use | Relation |
---|---|---|
Cats | Anesthesia | Indication |
Cats | General anesthesia for short procedures | Indication |
Cats | Induction and maintenance of general anesthesia | Indication |
Cats | General anesthesia | Indication |
Dogs | Anesthesia | Indication |
Dogs | General anesthesia for short procedures | Indication |
Dogs | Induction and maintenance of general anesthesia | Indication |
Dogs | General anesthesia | Indication |
Product | Applicant | Ingredients |
---|---|---|
Rapanofal | iVaoes Animal Health | 1 |
PropoFlo, PropoFlo 28 | Zoetis Inc. | 1 |
PropoClear | Zoetis Inc. | 1 |
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 10.8 | acidic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
GABA-A receptor alpha-1/beta-3/gamma-2 | Ion channel | POSITIVE ALLOSTERIC MODULATOR | EC50 | 5.39 | CHEMBL | CHEMBL | |||
GABA-A receptor alpha-1/beta-2/gamma-2 | Ion channel | POSITIVE ALLOSTERIC MODULATOR | EC50 | 5.70 | CHEMBL | CHEMBL | |||
GABA A receptor alpha-2/beta-2/gamma-2 | Ion channel | POSITIVE ALLOSTERIC MODULATOR | EC50 | 4.95 | CHEMBL | CHEMBL | |||
5-hydroxytryptamine receptor 2B | GPCR | Ki | 5.46 | DRUG MATRIX | |||||
5-hydroxytryptamine receptor 2C | GPCR | Ki | 5.22 | DRUG MATRIX | |||||
Carbonic anhydrase 2 | Enzyme | IC50 | 4.01 | WOMBAT-PK | |||||
Carbonic anhydrase 1 | Enzyme | IC50 | 4.71 | WOMBAT-PK | |||||
Fatty-acid amide hydrolase 1 | Enzyme | IC50 | 4.28 | WOMBAT-PK | |||||
Cytochrome P450 2C9 | Enzyme | IC50 | 4.91 | WOMBAT-PK | |||||
Prostaglandin G/H synthase 1 | Enzyme | IC50 | 5.42 | DRUG MATRIX | |||||
Sodium-dependent noradrenaline transporter | Transporter | Ki | 5.03 | DRUG MATRIX | |||||
Arachidonate 15-lipoxygenase | Enzyme | IC50 | 5.12 | DRUG MATRIX | |||||
Fatty-acid amide hydrolase 1 | Enzyme | IC50 | 4.85 | CHEMBL | |||||
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | Ion channel | BLOCKER | IC50 | 5.20 | IUPHAR | ||||
GABA-A receptor; anion channel | Ion channel | IC50 | 5.40 | CHEMBL |
ID | Source |
---|---|
4019500 | VUID |
N0000147620 | NUI |
D00549 | KEGG_DRUG |
4019500 | VANDF |
C0033487 | UMLSCUI |
CHEBI:44915 | CHEBI |
PFL | PDB_CHEM_ID |
CHEMBL526 | ChEMBL_ID |
DB00818 | DRUGBANK_ID |
D015742 | MESH_DESCRIPTOR_UI |
4943 | PUBCHEM_CID |
5073 | INN_ID |
5464 | IUPHAR_LIGAND_ID |
YI7VU623SF | UNII |
196459 | RXNORM |
14179 | MMSL |
5372 | MMSL |
65 | MMSL |
d00933 | MMSL |
003528 | NDDF |
387423006 | SNOMEDCT_US |
74674007 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-0209 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
Propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-0234 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
Propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-0248 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
Propofol Lipuro | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0264-4850 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | unapproved drug other | 3 sections |
PROPOFOL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0404-9943 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 14 sections |
PROPOFOL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-4699 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
PROPOFOL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-4699 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
PROPOFOL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-6010 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
Propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0591-2136 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
Propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0641-6194 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 24 sections |
Propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0641-6195 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 24 sections |
Propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0641-6196 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 24 sections |
Fresenius Propoven 2% | HUMAN PRESCRIPTION DRUG LABEL | 1 | 18124-027 | EMULSION | 20 mg | INTRAVENOUS | unapproved drug other | 2 sections |
propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 23155-345 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 23 sections |
propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 25021-608 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 27 sections |
Propofol Injectable Emulsion | HUMAN PRESCRIPTION DRUG LABEL | 1 | 43598-265 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 22 sections |
Propofol Injectable Emulsion | HUMAN PRESCRIPTION DRUG LABEL | 1 | 43598-548 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 22 sections |
Propofol Injectable Emulsion | HUMAN PRESCRIPTION DRUG LABEL | 1 | 43598-549 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 22 sections |
Propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-4569 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 27 sections |
PROPOFOL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51662-1293 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 14 sections |
PROPOFOL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51662-1470 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 14 sections |
PROPOFOL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51662-1471 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 14 sections |
PROPOFOL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 52584-098 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 14 sections |
Diprivan | HUMAN PRESCRIPTION DRUG LABEL | 1 | 52584-269 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | NDA | 12 sections |
Propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 52584-699 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 14 sections |
Diprivan | Human Prescription Drug Label | 1 | 63323-269 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | NDA | 14 sections |
Diprivan | Human Prescription Drug Label | 1 | 63323-269 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | NDA | 14 sections |
Diprivan | Human Prescription Drug Label | 1 | 63323-269 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | NDA | 14 sections |
Diprivan | Human Prescription Drug Label | 1 | 63323-269 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | NDA | 14 sections |
Fresenius Propoven 2% | HUMAN PRESCRIPTION DRUG LABEL | 1 | 65219-427 | EMULSION | 20 mg | INTRAVENOUS | unapproved drug other | 2 sections |