Stem definition | Drug id | CAS RN |
---|---|---|
2302 | 2078-54-8 |
None
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 2 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 0.16 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 0.50 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 14.02 µM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
Vd (Volume of distribution) | 4.70 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 36 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.02 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 3.20 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
Oct. 2, 1989 | FDA | FRESENIUS KABI USA |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Anaphylactic shock | 2122.65 | 15.37 | 718 | 31892 | 19556 | 46633896 |
Anaphylactic reaction | 898.94 | 15.37 | 522 | 32088 | 52590 | 46600862 |
Bronchospasm | 681.67 | 15.37 | 293 | 32317 | 15414 | 46638038 |
Hypotension | 648.95 | 15.37 | 803 | 31807 | 231786 | 46421666 |
Propofol infusion syndrome | 643.07 | 15.37 | 141 | 32469 | 640 | 46652812 |
Cardiac arrest | 575.84 | 15.37 | 488 | 32122 | 89911 | 46563541 |
Delayed recovery from anaesthesia | 346.49 | 15.37 | 87 | 32523 | 774 | 46652678 |
Circulatory collapse | 334.89 | 15.37 | 201 | 32409 | 21423 | 46632029 |
Tachycardia | 334.46 | 15.37 | 379 | 32231 | 99243 | 46554209 |
Status epilepticus | 320.15 | 15.37 | 168 | 32442 | 13811 | 46639641 |
Serotonin syndrome | 299.11 | 15.37 | 195 | 32415 | 24025 | 46629427 |
Hyperthermia malignant | 283.17 | 15.37 | 72 | 32538 | 677 | 46652775 |
Bradycardia | 276.43 | 15.37 | 283 | 32327 | 66015 | 46587437 |
Respiratory depression | 273.02 | 15.37 | 142 | 32468 | 11458 | 46641994 |
Stress cardiomyopathy | 238.52 | 15.37 | 114 | 32496 | 7670 | 46645782 |
Fatigue | 211.70 | 15.37 | 81 | 32529 | 608616 | 46044836 |
Neuromuscular block prolonged | 208.94 | 15.37 | 53 | 32557 | 493 | 46652959 |
Multiple organ dysfunction syndrome | 199.78 | 15.37 | 212 | 32398 | 51498 | 46601954 |
Oxygen saturation decreased | 190.38 | 15.37 | 238 | 32372 | 68926 | 46584526 |
Ventricular tachycardia | 188.65 | 15.37 | 128 | 32482 | 16839 | 46636613 |
Shock | 188.03 | 15.37 | 141 | 32469 | 21704 | 46631748 |
Drug interaction | 186.65 | 15.37 | 427 | 32183 | 202667 | 46450785 |
Ventricular fibrillation | 186.09 | 15.37 | 110 | 32500 | 11386 | 46642066 |
Diarrhoea | 185.47 | 15.37 | 80 | 32530 | 559522 | 46093930 |
Arthralgia | 179.63 | 15.37 | 22 | 32588 | 364581 | 46288871 |
Blood pressure decreased | 169.09 | 15.37 | 204 | 32406 | 56955 | 46596497 |
Procedural hypotension | 159.32 | 15.37 | 51 | 32559 | 1151 | 46652301 |
Pulseless electrical activity | 155.18 | 15.37 | 83 | 32527 | 7084 | 46646368 |
Anaesthetic complication | 153.61 | 15.37 | 55 | 32555 | 1762 | 46651690 |
Apnoea | 150.55 | 15.37 | 82 | 32528 | 7257 | 46646195 |
Unwanted awareness during anaesthesia | 149.98 | 15.37 | 36 | 32574 | 260 | 46653192 |
Metabolic acidosis | 144.46 | 15.37 | 156 | 32454 | 38624 | 46614828 |
Fall | 137.37 | 15.37 | 31 | 32579 | 329066 | 46324386 |
Dystonia | 134.92 | 15.37 | 89 | 32521 | 11168 | 46642284 |
Anaphylactoid shock | 133.64 | 15.37 | 33 | 32577 | 272 | 46653180 |
Rheumatoid arthritis | 132.85 | 15.37 | 9 | 32601 | 240206 | 46413246 |
Haemodynamic instability | 127.86 | 15.37 | 75 | 32535 | 7650 | 46645802 |
Diabetes insipidus | 126.27 | 15.37 | 50 | 32560 | 2124 | 46651328 |
Post procedural complication | 123.19 | 15.37 | 96 | 32514 | 15633 | 46637819 |
Procedural complication | 114.96 | 15.37 | 60 | 32550 | 4870 | 46648582 |
Rhabdomyolysis | 113.29 | 15.37 | 143 | 32467 | 41766 | 46611686 |
Airway complication of anaesthesia | 113.09 | 15.37 | 27 | 32583 | 190 | 46653262 |
Laryngospasm | 112.82 | 15.37 | 50 | 32560 | 2823 | 46650629 |
Headache | 110.74 | 15.37 | 103 | 32507 | 478249 | 46175203 |
Electrocardiogram ST segment elevation | 106.78 | 15.37 | 52 | 32558 | 3643 | 46649809 |
Hypoxia | 105.36 | 15.37 | 154 | 32456 | 51684 | 46601768 |
Respiratory acidosis | 105.21 | 15.37 | 61 | 32549 | 6087 | 46647365 |
Joint swelling | 102.23 | 15.37 | 3 | 32607 | 166070 | 46487382 |
Labile blood pressure | 101.83 | 15.37 | 40 | 32570 | 1663 | 46651789 |
Anaphylactoid reaction | 97.50 | 15.37 | 48 | 32562 | 3443 | 46650009 |
Clonus | 96.12 | 15.37 | 50 | 32560 | 4030 | 46649422 |
Malaise | 94.98 | 15.37 | 57 | 32553 | 331175 | 46322277 |
Hypoventilation | 92.93 | 15.37 | 49 | 32561 | 4061 | 46649391 |
Pain in extremity | 91.91 | 15.37 | 33 | 32577 | 258647 | 46394805 |
Dizziness | 90.25 | 15.37 | 64 | 32546 | 340350 | 46313102 |
Myoclonus | 90.08 | 15.37 | 77 | 32533 | 14275 | 46639177 |
Nausea | 89.52 | 15.37 | 220 | 32390 | 687234 | 45966218 |
Product dose omission issue | 85.75 | 15.37 | 9 | 32601 | 168511 | 46484941 |
Nasopharyngitis | 84.41 | 15.37 | 6 | 32604 | 153992 | 46499460 |
Alopecia | 84.40 | 15.37 | 8 | 32602 | 162406 | 46491046 |
PCO2 increased | 84.03 | 15.37 | 32 | 32578 | 1222 | 46652230 |
Type I hypersensitivity | 83.12 | 15.37 | 38 | 32572 | 2308 | 46651144 |
Tryptase increased | 83.10 | 15.37 | 21 | 32589 | 192 | 46653260 |
Drug intolerance | 82.75 | 15.37 | 5 | 32605 | 147044 | 46506408 |
Generalised tonic-clonic seizure | 82.10 | 15.37 | 98 | 32512 | 27024 | 46626428 |
Renal ischaemia | 81.62 | 15.37 | 26 | 32584 | 577 | 46652875 |
Arteriospasm coronary | 81.39 | 15.37 | 43 | 32567 | 3578 | 46649874 |
Weight decreased | 79.97 | 15.37 | 24 | 32586 | 210825 | 46442627 |
Respiratory failure | 79.90 | 15.37 | 193 | 32417 | 94623 | 46558829 |
Transmission of an infectious agent via product | 78.44 | 15.37 | 18 | 32592 | 104 | 46653348 |
Unresponsive to stimuli | 76.38 | 15.37 | 103 | 32507 | 32071 | 46621381 |
Anticholinergic syndrome | 76.00 | 15.37 | 33 | 32577 | 1773 | 46651679 |
Cardiogenic shock | 75.63 | 15.37 | 74 | 32536 | 16310 | 46637142 |
Intestinal ischaemia | 74.00 | 15.37 | 51 | 32559 | 6874 | 46646578 |
Opisthotonus | 73.55 | 15.37 | 21 | 32589 | 316 | 46653136 |
Anaesthetic complication pulmonary | 72.28 | 15.37 | 15 | 32595 | 49 | 46653403 |
Oliguria | 71.94 | 15.37 | 55 | 32555 | 8704 | 46644748 |
Product contamination | 71.72 | 15.37 | 23 | 32587 | 522 | 46652930 |
Mitochondrial DNULL mutation | 70.21 | 15.37 | 19 | 32591 | 232 | 46653220 |
Ventricular hypokinesia | 68.55 | 15.37 | 40 | 32570 | 4038 | 46649414 |
Dyspnoea | 68.51 | 15.37 | 163 | 32447 | 515385 | 46138067 |
Sinusitis | 68.46 | 15.37 | 6 | 32604 | 129762 | 46523690 |
Seizure | 68.33 | 15.37 | 215 | 32395 | 122839 | 46530613 |
Blood creatine phosphokinase increased | 67.71 | 15.37 | 90 | 32520 | 27634 | 46625818 |
Pain | 66.41 | 15.37 | 147 | 32463 | 476801 | 46176651 |
Insomnia | 65.82 | 15.37 | 17 | 32593 | 164907 | 46488545 |
Respiratory arrest | 65.15 | 15.37 | 98 | 32512 | 33718 | 46619734 |
PO2 increased | 64.31 | 15.37 | 24 | 32586 | 866 | 46652586 |
Blood gases abnormal | 64.24 | 15.37 | 22 | 32588 | 616 | 46652836 |
Weight increased | 63.66 | 15.37 | 18 | 32592 | 164455 | 46488997 |
Peripheral swelling | 63.64 | 15.37 | 16 | 32594 | 158055 | 46495397 |
Abdominal discomfort | 63.43 | 15.37 | 14 | 32596 | 151151 | 46502301 |
Intra-abdominal pressure increased | 63.16 | 15.37 | 17 | 32593 | 203 | 46653249 |
Cardio-respiratory arrest | 61.67 | 15.37 | 132 | 32478 | 59737 | 46593715 |
Encephalopathy | 61.40 | 15.37 | 95 | 32515 | 33494 | 46619958 |
Blood pH decreased | 61.33 | 15.37 | 32 | 32578 | 2595 | 46650857 |
Decreased appetite | 60.36 | 15.37 | 30 | 32580 | 193806 | 46459646 |
Oculogyric crisis | 60.08 | 15.37 | 25 | 32585 | 1208 | 46652244 |
Hyperreflexia | 59.24 | 15.37 | 40 | 32570 | 5214 | 46648238 |
Agitation | 59.19 | 15.37 | 124 | 32486 | 55291 | 46598161 |
Stridor | 58.61 | 15.37 | 33 | 32577 | 3114 | 46650338 |
Drug ineffective for unapproved indication | 57.56 | 15.37 | 64 | 32546 | 16349 | 46637103 |
Oxygen saturation abnormal | 57.49 | 15.37 | 31 | 32579 | 2687 | 46650765 |
Dyskinesia | 57.39 | 15.37 | 85 | 32525 | 28840 | 46624612 |
Constipation | 57.20 | 15.37 | 25 | 32585 | 174072 | 46479380 |
Disseminated intravascular coagulation | 56.41 | 15.37 | 68 | 32542 | 18937 | 46634515 |
Torsade de pointes | 56.29 | 15.37 | 55 | 32555 | 12099 | 46641353 |
Pneumatosis | 55.98 | 15.37 | 18 | 32592 | 412 | 46653040 |
Endotracheal intubation complication | 55.94 | 15.37 | 18 | 32592 | 413 | 46653039 |
Pulmonary oedema | 55.33 | 15.37 | 115 | 32495 | 50990 | 46602462 |
Anaesthetic complication neurological | 55.29 | 15.37 | 15 | 32595 | 185 | 46653267 |
Acute respiratory distress syndrome | 54.82 | 15.37 | 72 | 32538 | 21850 | 46631602 |
End-tidal CO2 decreased | 54.80 | 15.37 | 10 | 32600 | 12 | 46653440 |
Bronchitis | 53.02 | 15.37 | 6 | 32604 | 105973 | 46547479 |
Vasoplegia syndrome | 52.73 | 15.37 | 22 | 32588 | 1070 | 46652382 |
Erythema | 52.39 | 15.37 | 218 | 32392 | 142602 | 46510850 |
Septic shock | 52.16 | 15.37 | 121 | 32489 | 57772 | 46595680 |
Carcinoid crisis | 51.98 | 15.37 | 15 | 32595 | 235 | 46653217 |
Laryngeal oedema | 51.78 | 15.37 | 37 | 32573 | 5282 | 46648170 |
Death | 51.21 | 15.37 | 98 | 32512 | 335450 | 46318002 |
Ventricular extrasystoles | 51.12 | 15.37 | 50 | 32560 | 11013 | 46642439 |
Exposure during pregnancy | 51.07 | 15.37 | 179 | 32431 | 108033 | 46545419 |
Sinus tachycardia | 50.91 | 15.37 | 69 | 32541 | 21580 | 46631872 |
Pneumonia | 49.87 | 15.37 | 119 | 32491 | 376201 | 46277251 |
Brain oedema | 49.62 | 15.37 | 52 | 32558 | 12426 | 46641026 |
Maternal exposure during pregnancy | 48.71 | 15.37 | 170 | 32440 | 102379 | 46551073 |
Pruritus | 48.28 | 15.37 | 59 | 32551 | 242293 | 46411159 |
Upper airway obstruction | 48.12 | 15.37 | 17 | 32593 | 523 | 46652929 |
Atrioventricular block complete | 48.02 | 15.37 | 41 | 32569 | 7586 | 46645866 |
Influenza | 47.42 | 15.37 | 4 | 32606 | 89266 | 46564186 |
Foetal death | 47.05 | 15.37 | 43 | 32567 | 8700 | 46644752 |
Gene mutation | 46.31 | 15.37 | 20 | 32590 | 1060 | 46652392 |
Muscle rigidity | 45.99 | 15.37 | 45 | 32565 | 9916 | 46643536 |
Acute hepatic failure | 45.87 | 15.37 | 54 | 32556 | 14667 | 46638785 |
Hepatic ischaemia | 45.36 | 15.37 | 16 | 32594 | 490 | 46652962 |
Postoperative delirium | 45.30 | 15.37 | 10 | 32600 | 47 | 46653405 |
Coagulopathy | 45.08 | 15.37 | 60 | 32550 | 18439 | 46635013 |
Renal impairment | 45.03 | 15.37 | 134 | 32476 | 74238 | 46579214 |
Acute pulmonary oedema | 44.81 | 15.37 | 40 | 32570 | 7851 | 46645601 |
Urinary tract infection | 44.53 | 15.37 | 53 | 32557 | 220213 | 46433239 |
Arthropathy | 44.43 | 15.37 | 4 | 32606 | 84696 | 46568756 |
Electrocardiogram QRS complex prolonged | 44.27 | 15.37 | 34 | 32576 | 5415 | 46648037 |
Neuromuscular blockade | 43.98 | 15.37 | 14 | 32596 | 310 | 46653142 |
Mydriasis | 43.80 | 15.37 | 45 | 32565 | 10508 | 46642944 |
Psoriasis | 43.23 | 15.37 | 3 | 32607 | 78601 | 46574851 |
Therapeutic product effect prolonged | 43.19 | 15.37 | 14 | 32596 | 329 | 46653123 |
Back pain | 43.03 | 15.37 | 50 | 32560 | 209989 | 46443463 |
Gait disturbance | 42.96 | 15.37 | 24 | 32586 | 145239 | 46508213 |
Suspected product quality issue | 42.90 | 15.37 | 12 | 32598 | 167 | 46653285 |
Multiple-drug resistance | 42.69 | 15.37 | 25 | 32585 | 2540 | 46650912 |
Blood bicarbonate decreased | 42.52 | 15.37 | 26 | 32584 | 2859 | 46650593 |
Acute generalised exanthematous pustulosis | 42.51 | 15.37 | 42 | 32568 | 9363 | 46644089 |
Cardiovascular insufficiency | 42.17 | 15.37 | 20 | 32590 | 1321 | 46652131 |
Local anaesthetic systemic toxicity | 41.86 | 15.37 | 14 | 32596 | 364 | 46653088 |
Asthenia | 41.47 | 15.37 | 98 | 32512 | 310977 | 46342475 |
Contusion | 41.23 | 15.37 | 6 | 32604 | 87481 | 46565971 |
Mental status changes postoperative | 40.72 | 15.37 | 12 | 32598 | 203 | 46653249 |
Necrosis ischaemic | 40.72 | 15.37 | 17 | 32593 | 828 | 46652624 |
Chest pain | 40.59 | 15.37 | 38 | 32572 | 176286 | 46477166 |
Product contamination microbial | 39.98 | 15.37 | 12 | 32598 | 217 | 46653235 |
Confusion postoperative | 39.87 | 15.37 | 12 | 32598 | 219 | 46653233 |
Myoclonic epilepsy | 39.28 | 15.37 | 17 | 32593 | 906 | 46652546 |
Acidosis hyperchloraemic | 39.27 | 15.37 | 13 | 32597 | 327 | 46653125 |
Electrocardiogram ST segment depression | 39.00 | 15.37 | 24 | 32586 | 2669 | 46650783 |
Fear | 38.72 | 15.37 | 52 | 32558 | 16120 | 46637332 |
Hepatorenal failure | 38.47 | 15.37 | 15 | 32595 | 611 | 46652841 |
Shock haemorrhagic | 38.03 | 15.37 | 38 | 32572 | 8586 | 46644866 |
Hepatitis acute | 37.72 | 15.37 | 37 | 32573 | 8177 | 46645275 |
Injection site pain | 37.43 | 15.37 | 14 | 32596 | 107138 | 46546314 |
Laryngeal stenosis | 37.05 | 15.37 | 15 | 32595 | 675 | 46652777 |
Neuropathy peripheral | 36.95 | 15.37 | 9 | 32601 | 90884 | 46562568 |
Procedural nausea | 36.89 | 15.37 | 15 | 32595 | 683 | 46652769 |
Hepatorenal syndrome | 36.52 | 15.37 | 20 | 32590 | 1788 | 46651664 |
Neutropenia | 36.46 | 15.37 | 28 | 32582 | 143176 | 46510276 |
Stomatitis | 36.44 | 15.37 | 3 | 32607 | 68294 | 46585158 |
Electroencephalogram abnormal | 36.28 | 15.37 | 26 | 32584 | 3728 | 46649724 |
Pulse absent | 36.11 | 15.37 | 29 | 32581 | 4927 | 46648525 |
Oedema peripheral | 36.07 | 15.37 | 35 | 32575 | 159671 | 46493781 |
Musculoskeletal stiffness | 35.60 | 15.37 | 12 | 32598 | 97981 | 46555471 |
Left ventricle outflow tract obstruction | 35.56 | 15.37 | 11 | 32599 | 221 | 46653231 |
Posterior reversible encephalopathy syndrome | 35.20 | 15.37 | 48 | 32562 | 15093 | 46638359 |
Angioedema | 35.17 | 15.37 | 82 | 32528 | 39260 | 46614192 |
Perforation | 35.01 | 15.37 | 16 | 32594 | 971 | 46652481 |
Wrong product administered | 34.90 | 15.37 | 30 | 32580 | 5600 | 46647852 |
Subcutaneous emphysema | 34.43 | 15.37 | 15 | 32595 | 812 | 46652640 |
Left ventricular dysfunction | 34.27 | 15.37 | 39 | 32571 | 10216 | 46643236 |
Malignant neoplasm progression | 34.23 | 15.37 | 3 | 32607 | 64923 | 46588529 |
Hypocapnia | 34.22 | 15.37 | 12 | 32598 | 361 | 46653091 |
Infusion related reaction | 34.07 | 15.37 | 14 | 32596 | 101194 | 46552258 |
Paralysis | 34.06 | 15.37 | 36 | 32574 | 8685 | 46644767 |
Hepatocellular injury | 33.79 | 15.37 | 68 | 32542 | 29454 | 46623998 |
Hypercapnia | 33.56 | 15.37 | 27 | 32583 | 4599 | 46648853 |
Disease progression | 33.48 | 15.37 | 11 | 32599 | 91289 | 46562163 |
Muscle twitching | 33.34 | 15.37 | 46 | 32564 | 14626 | 46638826 |
Renal injury | 33.10 | 15.37 | 37 | 32573 | 9504 | 46643948 |
Cardiac output decreased | 33.03 | 15.37 | 15 | 32595 | 897 | 46652555 |
Myxoedema coma | 32.97 | 15.37 | 12 | 32598 | 403 | 46653049 |
Airway peak pressure increased | 32.92 | 15.37 | 11 | 32599 | 285 | 46653167 |
Unmasking of previously unidentified disease | 32.87 | 15.37 | 14 | 32596 | 717 | 46652735 |
Blood lactic acid increased | 32.77 | 15.37 | 29 | 32581 | 5628 | 46647824 |
Dehydration | 32.64 | 15.37 | 38 | 32572 | 159502 | 46493950 |
Delirium | 32.63 | 15.37 | 77 | 32533 | 37151 | 46616301 |
Skin test positive | 32.56 | 15.37 | 14 | 32596 | 734 | 46652718 |
Muscle relaxant therapy | 32.53 | 15.37 | 9 | 32601 | 120 | 46653332 |
Hepatitis | 31.98 | 15.37 | 70 | 32540 | 32145 | 46621307 |
Inappropriate schedule of product administration | 31.72 | 15.37 | 4 | 32606 | 65009 | 46588443 |
Coma scale abnormal | 31.69 | 15.37 | 27 | 32583 | 4979 | 46648473 |
Maternal exposure during delivery | 31.39 | 15.37 | 14 | 32596 | 802 | 46652650 |
Procedural haemorrhage | 31.37 | 15.37 | 20 | 32590 | 2366 | 46651086 |
Herpes zoster | 31.19 | 15.37 | 5 | 32605 | 67867 | 46585585 |
Feeling abnormal | 31.14 | 15.37 | 25 | 32585 | 125035 | 46528417 |
Extravasation | 31.01 | 15.37 | 19 | 32591 | 2096 | 46651356 |
Injection site erythema | 30.98 | 15.37 | 7 | 32603 | 74420 | 46579032 |
Swelling | 30.86 | 15.37 | 25 | 32585 | 124486 | 46528966 |
Myoglobinuria | 30.85 | 15.37 | 10 | 32600 | 235 | 46653217 |
Oropharyngeal pain | 30.83 | 15.37 | 7 | 32603 | 74161 | 46579291 |
Altered state of consciousness | 30.66 | 15.37 | 57 | 32553 | 23291 | 46630161 |
Procedural vomiting | 30.63 | 15.37 | 12 | 32598 | 495 | 46652957 |
Arrhythmia | 30.47 | 15.37 | 72 | 32538 | 34769 | 46618683 |
Premature delivery | 30.40 | 15.37 | 55 | 32555 | 22014 | 46631438 |
Depression | 30.21 | 15.37 | 45 | 32565 | 170059 | 46483393 |
Lipoedema | 30.18 | 15.37 | 9 | 32601 | 159 | 46653293 |
Recurrence of neuromuscular blockade | 29.76 | 15.37 | 8 | 32602 | 95 | 46653357 |
Systemic lupus erythematosus | 29.51 | 15.37 | 5 | 32605 | 65175 | 46588277 |
Haemodilution | 29.46 | 15.37 | 8 | 32602 | 99 | 46653353 |
Somatosensory evoked potentials abnormal | 28.99 | 15.37 | 5 | 32605 | 3 | 46653449 |
Renal failure | 28.90 | 15.37 | 156 | 32454 | 113438 | 46540014 |
Blood pressure immeasurable | 28.80 | 15.37 | 15 | 32595 | 1212 | 46652240 |
Coma | 28.79 | 15.37 | 98 | 32512 | 58251 | 46595201 |
Hypovolaemia | 28.72 | 15.37 | 35 | 32575 | 9853 | 46643599 |
Neuroleptic malignant syndrome | 28.53 | 15.37 | 37 | 32573 | 11085 | 46642367 |
Acute postoperative sialadenitis | 28.38 | 15.37 | 6 | 32604 | 22 | 46653430 |
Ventricular dysfunction | 28.26 | 15.37 | 20 | 32590 | 2812 | 46650640 |
Vitamin K deficiency | 28.10 | 15.37 | 11 | 32599 | 453 | 46652999 |
Aspartate aminotransferase increased | 27.94 | 15.37 | 119 | 32491 | 78581 | 46574871 |
Abdominal pain | 27.89 | 15.37 | 76 | 32534 | 229955 | 46423497 |
Lower respiratory tract infection | 27.84 | 15.37 | 3 | 32607 | 55086 | 46598366 |
Procedural hypertension | 27.84 | 15.37 | 10 | 32600 | 323 | 46653129 |
Dry mouth | 27.74 | 15.37 | 3 | 32607 | 54923 | 46598529 |
Atrioventricular dissociation | 27.59 | 15.37 | 9 | 32601 | 216 | 46653236 |
Cyanosis | 27.55 | 15.37 | 44 | 32566 | 15927 | 46637525 |
Pupils unequal | 27.51 | 15.37 | 15 | 32595 | 1329 | 46652123 |
Asthma | 27.23 | 15.37 | 15 | 32595 | 91527 | 46561925 |
Abdominal pain upper | 27.22 | 15.37 | 37 | 32573 | 145268 | 46508184 |
Atrioventricular block second degree | 27.19 | 15.37 | 22 | 32588 | 3777 | 46649675 |
Anaemia | 27.07 | 15.37 | 90 | 32520 | 255689 | 46397763 |
Hypoaesthesia | 26.89 | 15.37 | 26 | 32584 | 118843 | 46534609 |
Hypertriglyceridaemia | 26.76 | 15.37 | 26 | 32584 | 5678 | 46647774 |
Myoglobin urine present | 26.53 | 15.37 | 7 | 32603 | 77 | 46653375 |
Myotonia | 26.38 | 15.37 | 8 | 32602 | 150 | 46653302 |
Acute kidney injury | 26.34 | 15.37 | 266 | 32344 | 235589 | 46417863 |
Toxic epidermal necrolysis | 26.32 | 15.37 | 52 | 32558 | 22226 | 46631226 |
Ultrasound ovary abnormal | 26.29 | 15.37 | 7 | 32603 | 80 | 46653372 |
Thyrotoxic crisis | 26.18 | 15.37 | 12 | 32598 | 733 | 46652719 |
Syncope | 26.02 | 15.37 | 21 | 32589 | 104782 | 46548670 |
Electrocardiogram QT prolonged | 26.02 | 15.37 | 87 | 32523 | 51238 | 46602214 |
Oesophageal intramural haematoma | 25.98 | 15.37 | 7 | 32603 | 84 | 46653368 |
Hepatic failure | 25.97 | 15.37 | 66 | 32544 | 33350 | 46620102 |
Anhedonia | 25.92 | 15.37 | 34 | 32576 | 10301 | 46643151 |
Irregular breathing | 25.79 | 15.37 | 9 | 32601 | 267 | 46653185 |
Gastrooesophageal reflux disease | 25.48 | 15.37 | 10 | 32600 | 74334 | 46579118 |
Contraindicated product administered | 25.42 | 15.37 | 12 | 32598 | 79935 | 46573517 |
Hypotensive transfusion reaction | 25.28 | 15.37 | 6 | 32604 | 41 | 46653411 |
Gaze palsy | 25.23 | 15.37 | 14 | 32596 | 1284 | 46652168 |
Sinus bradycardia | 25.20 | 15.37 | 39 | 32571 | 13743 | 46639709 |
Patent ductus arteriosus | 24.80 | 15.37 | 21 | 32589 | 3841 | 46649611 |
Bezold-Jarisch reflex | 24.67 | 15.37 | 5 | 32605 | 14 | 46653438 |
Intensive care unit acquired weakness | 24.67 | 15.37 | 11 | 32599 | 630 | 46652822 |
Diabetes mellitus | 24.62 | 15.37 | 3 | 32607 | 50062 | 46603390 |
Hyperammonaemic encephalopathy | 24.55 | 15.37 | 16 | 32594 | 1966 | 46651486 |
Coronary artery embolism | 24.44 | 15.37 | 8 | 32602 | 194 | 46653258 |
Depressed level of consciousness | 24.44 | 15.37 | 81 | 32529 | 47488 | 46605964 |
Post procedural haemorrhage | 24.40 | 15.37 | 28 | 32582 | 7398 | 46646054 |
Anaesthetic complication cardiac | 24.17 | 15.37 | 5 | 32605 | 16 | 46653436 |
Gastrointestinal disorder | 24.01 | 15.37 | 6 | 32604 | 59570 | 46593882 |
Tracheal injury | 23.83 | 15.37 | 6 | 32604 | 54 | 46653398 |
Chest discomfort | 23.80 | 15.37 | 17 | 32593 | 90252 | 46563200 |
White blood cell count decreased | 23.74 | 15.37 | 26 | 32584 | 112205 | 46541247 |
Alanine aminotransferase increased | 23.53 | 15.37 | 123 | 32487 | 88328 | 46565124 |
Kounis syndrome | 23.46 | 15.37 | 13 | 32597 | 1189 | 46652263 |
Muscle spasms | 23.41 | 15.37 | 31 | 32579 | 123082 | 46530370 |
Suspected product contamination | 23.11 | 15.37 | 5 | 32605 | 21 | 46653431 |
Skin test negative | 23.11 | 15.37 | 5 | 32605 | 21 | 46653431 |
Macroglossia | 22.98 | 15.37 | 10 | 32600 | 540 | 46652912 |
Electrocardiogram repolarisation abnormality | 22.84 | 15.37 | 13 | 32597 | 1252 | 46652200 |
Trigemino-cardiac reflex | 22.83 | 15.37 | 4 | 32606 | 3 | 46653449 |
Air embolism | 22.74 | 15.37 | 8 | 32602 | 243 | 46653209 |
Hospitalisation | 22.61 | 15.37 | 8 | 32602 | 63377 | 46590075 |
Abscess neck | 22.55 | 15.37 | 10 | 32600 | 565 | 46652887 |
Post procedural fever | 22.47 | 15.37 | 8 | 32602 | 252 | 46653200 |
Systemic inflammatory response syndrome | 22.46 | 15.37 | 23 | 32587 | 5348 | 46648104 |
Vision blurred | 22.38 | 15.37 | 14 | 32596 | 79694 | 46573758 |
Foetal exposure during pregnancy | 22.12 | 15.37 | 59 | 32551 | 30688 | 46622764 |
Obstructive airways disorder | 21.84 | 15.37 | 36 | 32574 | 13376 | 46640076 |
Urticaria | 21.77 | 15.37 | 149 | 32461 | 117743 | 46535709 |
Atrioventricular block first degree | 21.48 | 15.37 | 24 | 32586 | 6162 | 46647290 |
Neck pain | 21.47 | 15.37 | 6 | 32604 | 55300 | 46598152 |
Tachypnoea | 21.35 | 15.37 | 37 | 32573 | 14314 | 46639138 |
Palpitations | 21.35 | 15.37 | 21 | 32589 | 95238 | 46558214 |
Nasal congestion | 21.11 | 15.37 | 4 | 32606 | 48109 | 46605343 |
Cough | 21.08 | 15.37 | 86 | 32524 | 230163 | 46423289 |
Premature baby | 21.06 | 15.37 | 42 | 32568 | 18070 | 46635382 |
Upper respiratory tract infection | 21.05 | 15.37 | 9 | 32601 | 63547 | 46589905 |
Chronic obstructive pulmonary disease | 21.03 | 15.37 | 7 | 32603 | 57626 | 46595826 |
Endotracheal intubation | 20.93 | 15.37 | 15 | 32595 | 2150 | 46651302 |
Burkholderia test positive | 20.79 | 15.37 | 6 | 32604 | 94 | 46653358 |
Supraventricular tachycardia | 20.78 | 15.37 | 35 | 32575 | 13235 | 46640217 |
Loss of personal independence in daily activities | 20.77 | 15.37 | 7 | 32603 | 57176 | 46596276 |
Dyspepsia | 20.68 | 15.37 | 11 | 32599 | 68461 | 46584991 |
Extrasystoles | 20.64 | 15.37 | 21 | 32589 | 4848 | 46648604 |
Tidal volume decreased | 20.49 | 15.37 | 5 | 32605 | 39 | 46653413 |
Intensive care unit delirium | 20.38 | 15.37 | 5 | 32605 | 40 | 46653412 |
Tongue oedema | 20.20 | 15.37 | 19 | 32591 | 3987 | 46649465 |
Musculoskeletal pain | 20.13 | 15.37 | 12 | 32598 | 70116 | 46583336 |
Medication error | 19.94 | 15.37 | 57 | 32553 | 30854 | 46622598 |
Drug use disorder | 19.92 | 15.37 | 16 | 32594 | 2719 | 46650733 |
Epistaxis | 19.91 | 15.37 | 10 | 32600 | 64295 | 46589157 |
Eosinophilic pneumonia acute | 19.83 | 15.37 | 8 | 32602 | 357 | 46653095 |
Respiratory distress | 19.77 | 15.37 | 58 | 32552 | 31858 | 46621594 |
Device programming error | 19.76 | 15.37 | 5 | 32605 | 46 | 46653406 |
Infantile apnoea | 19.69 | 15.37 | 10 | 32600 | 766 | 46652686 |
Cystitis | 19.66 | 15.37 | 3 | 32607 | 42238 | 46611214 |
Acidosis | 19.57 | 15.37 | 31 | 32579 | 11143 | 46642309 |
Hypovolaemic shock | 19.54 | 15.37 | 21 | 32589 | 5162 | 46648290 |
Cardiac massage | 19.29 | 15.37 | 4 | 32606 | 13 | 46653439 |
Hypervolaemia | 19.15 | 15.37 | 13 | 32597 | 1709 | 46651743 |
Idiosyncratic drug reaction | 19.09 | 15.37 | 10 | 32600 | 817 | 46652635 |
Therapeutic product effect incomplete | 18.98 | 15.37 | 16 | 32594 | 78137 | 46575315 |
Transcranial electrical motor evoked potential monitoring abnormal | 18.80 | 15.37 | 3 | 32607 | 0 | 46653452 |
Bispectral index decreased | 18.80 | 15.37 | 3 | 32607 | 0 | 46653452 |
Peripheral nerve palsy | 18.64 | 15.37 | 4 | 32606 | 16 | 46653436 |
Extubation | 18.64 | 15.37 | 4 | 32606 | 16 | 46653436 |
Administration site extravasation | 18.60 | 15.37 | 9 | 32601 | 621 | 46652831 |
Drug-induced liver injury | 18.58 | 15.37 | 49 | 32561 | 25319 | 46628133 |
Blood magnesium decreased | 18.57 | 15.37 | 30 | 32580 | 10962 | 46642490 |
Lactic acidosis | 18.55 | 15.37 | 59 | 32551 | 33850 | 46619602 |
Sepsis syndrome | 18.47 | 15.37 | 10 | 32600 | 874 | 46652578 |
Neurological decompensation | 18.32 | 15.37 | 13 | 32597 | 1835 | 46651617 |
Long QT syndrome | 18.26 | 15.37 | 16 | 32594 | 3064 | 46650388 |
Hypoxic-ischaemic encephalopathy | 18.06 | 15.37 | 18 | 32592 | 4055 | 46649397 |
Euthyroid sick syndrome | 18.05 | 15.37 | 5 | 32605 | 67 | 46653385 |
Apnoeic attack | 17.91 | 15.37 | 7 | 32603 | 287 | 46653165 |
Tracheal haemorrhage | 17.90 | 15.37 | 6 | 32604 | 157 | 46653295 |
Uterine atony | 17.83 | 15.37 | 6 | 32604 | 159 | 46653293 |
Ischaemic cerebral infarction | 17.79 | 15.37 | 11 | 32599 | 1234 | 46652218 |
Mucosal inflammation | 17.62 | 15.37 | 3 | 32607 | 38973 | 46614479 |
Hypernatraemia | 17.53 | 15.37 | 22 | 32588 | 6379 | 46647073 |
Haematemesis | 17.51 | 15.37 | 52 | 32558 | 28754 | 46624698 |
Brain death | 17.41 | 15.37 | 15 | 32595 | 2808 | 46650644 |
Systolic dysfunction | 17.24 | 15.37 | 11 | 32599 | 1303 | 46652149 |
Balance disorder | 17.21 | 15.37 | 12 | 32598 | 64509 | 46588943 |
Face oedema | 17.20 | 15.37 | 40 | 32570 | 19113 | 46634339 |
Stevens-Johnson syndrome | 17.06 | 15.37 | 45 | 32565 | 23252 | 46630200 |
Haemoperitoneum | 16.98 | 15.37 | 14 | 32596 | 2468 | 46650984 |
Procedural dizziness | 16.94 | 15.37 | 5 | 32605 | 85 | 46653367 |
Ventricular asystole | 16.94 | 15.37 | 5 | 32605 | 85 | 46653367 |
Abdominal sepsis | 16.92 | 15.37 | 11 | 32599 | 1346 | 46652106 |
Burning sensation | 16.91 | 15.37 | 5 | 32605 | 44406 | 46609046 |
Dry skin | 16.78 | 15.37 | 4 | 32606 | 41012 | 46612440 |
Agitation postoperative | 16.77 | 15.37 | 4 | 32606 | 28 | 46653424 |
Nerve stimulation test abnormal | 16.73 | 15.37 | 3 | 32607 | 3 | 46653449 |
Partial seizures | 16.65 | 15.37 | 19 | 32591 | 4991 | 46648461 |
Bone pain | 16.58 | 15.37 | 6 | 32604 | 46884 | 46606568 |
Fat embolism | 16.44 | 15.37 | 6 | 32604 | 203 | 46653249 |
Acute chest syndrome | 16.40 | 15.37 | 8 | 32602 | 562 | 46652890 |
Infection | 16.27 | 15.37 | 44 | 32566 | 133548 | 46519904 |
Bradycardia foetal | 16.24 | 15.37 | 7 | 32603 | 369 | 46653083 |
Encephalitis autoimmune | 16.23 | 15.37 | 10 | 32600 | 1114 | 46652338 |
Migraine | 16.20 | 15.37 | 15 | 32595 | 70011 | 46583441 |
Chemical peritonitis | 16.18 | 15.37 | 5 | 32605 | 100 | 46653352 |
Hepatitis C | 16.18 | 15.37 | 21 | 32589 | 6297 | 46647155 |
Respiratory rate decreased | 16.16 | 15.37 | 15 | 32595 | 3095 | 46650357 |
Spinal cord disorder | 16.15 | 15.37 | 10 | 32600 | 1124 | 46652328 |
Suicidal ideation | 15.69 | 15.37 | 10 | 32600 | 56372 | 46597080 |
Emotional distress | 15.51 | 15.37 | 52 | 32558 | 30655 | 46622797 |
Polyuria | 15.51 | 15.37 | 22 | 32588 | 7173 | 46646279 |
Myalgia | 15.40 | 15.37 | 40 | 32570 | 123048 | 46530404 |
Rhinorrhoea | 15.39 | 15.37 | 7 | 32603 | 47658 | 46605794 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Anaphylactic shock | 1421.32 | 15.78 | 535 | 30087 | 13458 | 29908398 |
Propofol infusion syndrome | 1072.81 | 15.78 | 234 | 30388 | 632 | 29921224 |
Anaphylactic reaction | 680.70 | 15.78 | 398 | 30224 | 27584 | 29894272 |
Hyperthermia malignant | 509.54 | 15.78 | 150 | 30472 | 1684 | 29920172 |
Hypotension | 439.17 | 15.78 | 755 | 29867 | 199810 | 29722046 |
Cardiac arrest | 406.78 | 15.78 | 487 | 30135 | 92363 | 29829493 |
Bronchospasm | 367.13 | 15.78 | 189 | 30433 | 10149 | 29911707 |
Bradycardia | 318.84 | 15.78 | 363 | 30259 | 65163 | 29856693 |
Delayed recovery from anaesthesia | 306.34 | 15.78 | 82 | 30540 | 629 | 29921227 |
Rhabdomyolysis | 290.45 | 15.78 | 341 | 30281 | 63239 | 29858617 |
Serotonin syndrome | 268.81 | 15.78 | 188 | 30434 | 17703 | 29904153 |
Anaesthetic complication | 222.35 | 15.78 | 70 | 30552 | 999 | 29920857 |
Fatigue | 215.95 | 15.78 | 35 | 30587 | 320638 | 29601218 |
Tachycardia | 214.64 | 15.78 | 317 | 30305 | 73422 | 29848434 |
Metabolic acidosis | 189.56 | 15.78 | 212 | 30410 | 37249 | 29884607 |
Circulatory collapse | 176.26 | 15.78 | 154 | 30468 | 20060 | 29901796 |
Ventricular fibrillation | 156.00 | 15.78 | 127 | 30495 | 15011 | 29906845 |
Oxygen saturation decreased | 148.80 | 15.78 | 202 | 30420 | 43238 | 29878618 |
Neuromuscular block prolonged | 142.30 | 15.78 | 39 | 30583 | 330 | 29921526 |
Pulseless electrical activity | 142.26 | 15.78 | 85 | 30537 | 6102 | 29915754 |
Blood pressure decreased | 131.97 | 15.78 | 199 | 30423 | 46876 | 29874980 |
Diarrhoea | 131.24 | 15.78 | 91 | 30531 | 334012 | 29587844 |
Status epilepticus | 129.31 | 15.78 | 100 | 30522 | 10972 | 29910884 |
Electrocardiogram ST segment elevation | 128.83 | 15.78 | 71 | 30551 | 4371 | 29917485 |
Haemodynamic instability | 122.13 | 15.78 | 85 | 30537 | 7930 | 29913926 |
Shock | 121.84 | 15.78 | 133 | 30489 | 22726 | 29899130 |
Respiratory depression | 113.26 | 15.78 | 94 | 30528 | 11409 | 29910447 |
Fall | 107.25 | 15.78 | 27 | 30595 | 181845 | 29740011 |
Death | 107.18 | 15.78 | 125 | 30497 | 357158 | 29564698 |
Intensive care unit acquired weakness | 101.77 | 15.78 | 37 | 30585 | 835 | 29921021 |
Airway complication of anaesthesia | 99.77 | 15.78 | 24 | 30598 | 112 | 29921744 |
Ventricular tachycardia | 98.93 | 15.78 | 122 | 30500 | 23740 | 29898116 |
Post procedural complication | 95.54 | 15.78 | 86 | 30536 | 11640 | 29910216 |
Arthralgia | 92.96 | 15.78 | 14 | 30608 | 135777 | 29786079 |
Decreased appetite | 90.81 | 15.78 | 21 | 30601 | 149889 | 29771967 |
Laryngospasm | 89.58 | 15.78 | 38 | 30584 | 1305 | 29920551 |
Hypoxia | 88.42 | 15.78 | 168 | 30454 | 47686 | 29874170 |
Hypoxic-ischaemic encephalopathy | 86.51 | 15.78 | 56 | 30566 | 4631 | 29917225 |
Blood creatine phosphokinase increased | 86.08 | 15.78 | 158 | 30464 | 43690 | 29878166 |
Multiple organ dysfunction syndrome | 85.80 | 15.78 | 196 | 30426 | 63291 | 29858565 |
Drug interaction | 84.42 | 15.78 | 415 | 30207 | 199153 | 29722703 |
Negative pressure pulmonary oedema | 83.46 | 15.78 | 23 | 30599 | 199 | 29921657 |
Dizziness | 81.90 | 15.78 | 49 | 30573 | 194860 | 29726996 |
Anaphylactoid shock | 81.25 | 15.78 | 26 | 30596 | 392 | 29921464 |
Procedural complication | 78.77 | 15.78 | 52 | 30570 | 4445 | 29917411 |
Anaesthetic complication neurological | 74.11 | 15.78 | 23 | 30599 | 312 | 29921544 |
Fear | 73.96 | 15.78 | 72 | 30550 | 10753 | 29911103 |
Arteriospasm coronary | 73.59 | 15.78 | 41 | 30581 | 2577 | 29919279 |
Respiratory acidosis | 72.18 | 15.78 | 48 | 30574 | 4154 | 29917702 |
Stress cardiomyopathy | 71.87 | 15.78 | 34 | 30588 | 1515 | 29920341 |
Injury | 71.25 | 15.78 | 99 | 30523 | 21632 | 29900224 |
Hypertriglyceridaemia | 71.16 | 15.78 | 62 | 30560 | 8036 | 29913820 |
Diabetes insipidus | 71.07 | 15.78 | 38 | 30584 | 2201 | 29919655 |
Apnoea | 69.76 | 15.78 | 55 | 30567 | 6203 | 29915653 |
Headache | 69.59 | 15.78 | 51 | 30571 | 182255 | 29739601 |
Vasoplegia syndrome | 68.65 | 15.78 | 31 | 30591 | 1240 | 29920616 |
Procedural hypotension | 68.36 | 15.78 | 29 | 30593 | 996 | 29920860 |
Trigemino-cardiac reflex | 66.96 | 15.78 | 17 | 30605 | 103 | 29921753 |
Product dose omission issue | 66.12 | 15.78 | 8 | 30614 | 91623 | 29830233 |
Transmission of an infectious agent via product | 65.91 | 15.78 | 18 | 30604 | 150 | 29921706 |
Malaise | 63.33 | 15.78 | 47 | 30575 | 166915 | 29754941 |
Myoclonus | 63.28 | 15.78 | 73 | 30549 | 13239 | 29908617 |
Pulse absent | 62.95 | 15.78 | 49 | 30573 | 5424 | 29916432 |
Seizure like phenomena | 62.93 | 15.78 | 23 | 30599 | 527 | 29921329 |
Cyanosis | 62.80 | 15.78 | 69 | 30553 | 11866 | 29909990 |
Asthenia | 62.39 | 15.78 | 81 | 30541 | 221209 | 29700647 |
Brain oedema | 62.35 | 15.78 | 70 | 30552 | 12328 | 29909528 |
Renal injury | 62.05 | 15.78 | 68 | 30554 | 11661 | 29910195 |
Pain in extremity | 61.82 | 15.78 | 18 | 30604 | 110203 | 29811653 |
Drug level changed | 60.83 | 15.78 | 20 | 30602 | 330 | 29921526 |
Agitation | 60.25 | 15.78 | 155 | 30467 | 53918 | 29867938 |
Tachypnoea | 59.64 | 15.78 | 75 | 30547 | 14877 | 29906979 |
Ventricular arrhythmia | 57.32 | 15.78 | 42 | 30580 | 4246 | 29917610 |
Anaemia | 56.71 | 15.78 | 78 | 30544 | 207914 | 29713942 |
Erythema | 56.57 | 15.78 | 191 | 30431 | 77260 | 29844596 |
Nausea | 56.45 | 15.78 | 139 | 30483 | 296818 | 29625038 |
Dystonia | 56.04 | 15.78 | 59 | 30563 | 9668 | 29912188 |
Kounis syndrome | 54.81 | 15.78 | 29 | 30593 | 1644 | 29920212 |
Post procedural fever | 54.70 | 15.78 | 16 | 30606 | 175 | 29921681 |
Anhedonia | 54.08 | 15.78 | 54 | 30568 | 8315 | 29913541 |
Muscle rigidity | 53.43 | 15.78 | 59 | 30563 | 10202 | 29911654 |
Intestinal ischaemia | 53.07 | 15.78 | 49 | 30573 | 6848 | 29915008 |
Hypoventilation | 53.05 | 15.78 | 35 | 30587 | 2988 | 29918868 |
Autonomic nervous system imbalance | 52.39 | 15.78 | 32 | 30590 | 2389 | 29919467 |
Tryptase increased | 52.04 | 15.78 | 16 | 30606 | 210 | 29921646 |
Toxic epidermal necrolysis | 51.87 | 15.78 | 77 | 30545 | 17863 | 29903993 |
Weight decreased | 51.61 | 15.78 | 47 | 30575 | 150874 | 29770982 |
Dyspnoea | 49.59 | 15.78 | 175 | 30447 | 333120 | 29588736 |
Blood lactic acid increased | 47.95 | 15.78 | 43 | 30579 | 5787 | 29916069 |
Peripheral swelling | 47.50 | 15.78 | 4 | 30618 | 61070 | 29860786 |
Respiratory failure | 47.29 | 15.78 | 216 | 30406 | 100426 | 29821430 |
Necrosis ischaemic | 47.07 | 15.78 | 15 | 30607 | 223 | 29921633 |
Abdominal pain | 46.67 | 15.78 | 42 | 30580 | 135612 | 29786244 |
Acute respiratory distress syndrome | 46.56 | 15.78 | 85 | 30537 | 23387 | 29898469 |
Cardio-respiratory arrest | 46.02 | 15.78 | 146 | 30476 | 57160 | 29864696 |
Sinus arrest | 46.01 | 15.78 | 25 | 30597 | 1495 | 29920361 |
Respiratory arrest | 45.93 | 15.78 | 96 | 30526 | 29162 | 29892694 |
Endotracheal intubation complication | 45.48 | 15.78 | 16 | 30606 | 327 | 29921529 |
Product contamination | 45.41 | 15.78 | 19 | 30603 | 630 | 29921226 |
Dehydration | 45.25 | 15.78 | 36 | 30586 | 123503 | 29798353 |
Neuropathy peripheral | 44.39 | 15.78 | 9 | 30613 | 70466 | 29851390 |
Weight increased | 44.31 | 15.78 | 11 | 30611 | 74902 | 29846954 |
Blood pressure measurement | 44.21 | 15.78 | 13 | 30609 | 145 | 29921711 |
Sinus tachycardia | 44.04 | 15.78 | 66 | 30556 | 15438 | 29906418 |
Hepatorenal failure | 43.33 | 15.78 | 18 | 30604 | 586 | 29921270 |
Acidosis | 43.21 | 15.78 | 53 | 30569 | 10248 | 29911608 |
Disease progression | 43.05 | 15.78 | 14 | 30608 | 79860 | 29841996 |
Oxygen saturation immeasurable | 42.05 | 15.78 | 10 | 30612 | 44 | 29921812 |
Malignant neoplasm progression | 42.01 | 15.78 | 11 | 30611 | 72276 | 29849580 |
Type I hypersensitivity | 41.52 | 15.78 | 20 | 30602 | 928 | 29920928 |
Constipation | 41.22 | 15.78 | 33 | 30589 | 112873 | 29808983 |
Anticholinergic syndrome | 41.05 | 15.78 | 19 | 30603 | 805 | 29921051 |
Anaesthetic complication cardiac | 41.05 | 15.78 | 9 | 30613 | 25 | 29921831 |
Gait disturbance | 40.48 | 15.78 | 13 | 30609 | 74764 | 29847092 |
Febrile neutropenia | 40.45 | 15.78 | 30 | 30592 | 106663 | 29815193 |
Anaphylactoid reaction | 40.05 | 15.78 | 26 | 30596 | 2160 | 29919696 |
Brugada syndrome | 39.87 | 15.78 | 17 | 30605 | 591 | 29921265 |
Opisthotonus | 39.52 | 15.78 | 15 | 30607 | 383 | 29921473 |
Pneumonia | 39.43 | 15.78 | 192 | 30430 | 334114 | 29587742 |
Feeling abnormal | 38.45 | 15.78 | 6 | 30616 | 56750 | 29865106 |
Neonatal respiratory depression | 38.29 | 15.78 | 15 | 30607 | 418 | 29921438 |
Hyperammonaemia | 38.24 | 15.78 | 37 | 30585 | 5483 | 29916373 |
Coma blister | 38.15 | 15.78 | 10 | 30612 | 70 | 29921786 |
Pulmonary alveolar haemorrhage | 38.05 | 15.78 | 40 | 30582 | 6541 | 29915315 |
Plasma cell myeloma | 37.74 | 15.78 | 5 | 30617 | 53457 | 29868399 |
Airway peak pressure increased | 37.68 | 15.78 | 8 | 30614 | 18 | 29921838 |
Hypotonic-hyporesponsive episode | 37.68 | 15.78 | 8 | 30614 | 18 | 29921838 |
Emotional distress | 37.68 | 15.78 | 62 | 30560 | 15703 | 29906153 |
Intracranial pressure increased | 37.46 | 15.78 | 30 | 30592 | 3460 | 29918396 |
Hypercapnia | 37.11 | 15.78 | 31 | 30591 | 3793 | 29918063 |
Insomnia | 37.02 | 15.78 | 25 | 30597 | 93311 | 29828545 |
Superinfection | 36.64 | 15.78 | 22 | 30600 | 1592 | 29920264 |
Pulmonary oedema | 36.18 | 15.78 | 113 | 30509 | 43862 | 29877994 |
Oedema peripheral | 36.10 | 15.78 | 33 | 30589 | 105799 | 29816057 |
Neuromuscular blockade | 35.73 | 15.78 | 11 | 30611 | 145 | 29921711 |
Haemodialysis | 35.62 | 15.78 | 50 | 30572 | 11023 | 29910833 |
Mean arterial pressure decreased | 35.53 | 15.78 | 11 | 30611 | 148 | 29921708 |
White blood cell count decreased | 35.33 | 15.78 | 21 | 30601 | 83926 | 29837930 |
Cough | 35.32 | 15.78 | 46 | 30576 | 125596 | 29796260 |
Post procedural haemorrhage | 35.30 | 15.78 | 42 | 30580 | 7868 | 29913988 |
Back pain | 34.99 | 15.78 | 32 | 30590 | 102564 | 29819292 |
Urticaria | 34.96 | 15.78 | 129 | 30493 | 54477 | 29867379 |
Areflexia | 34.92 | 15.78 | 26 | 30596 | 2693 | 29919163 |
Urinary tract infection | 34.58 | 15.78 | 16 | 30606 | 73643 | 29848213 |
Oculocardiac reflex | 34.46 | 15.78 | 9 | 30613 | 62 | 29921794 |
Brain injury | 34.38 | 15.78 | 35 | 30587 | 5513 | 29916343 |
Cardiac failure congestive | 34.29 | 15.78 | 22 | 30600 | 84385 | 29837471 |
Neutropenia | 34.19 | 15.78 | 49 | 30573 | 128491 | 29793365 |
Neuroleptic malignant syndrome | 33.57 | 15.78 | 60 | 30562 | 16235 | 29905621 |
Therapeutic product effect prolonged | 32.87 | 15.78 | 12 | 30610 | 274 | 29921582 |
Postoperative delirium | 32.48 | 15.78 | 8 | 30614 | 42 | 29921814 |
Product contamination microbial | 32.16 | 15.78 | 15 | 30607 | 647 | 29921209 |
Pancytopenia | 32.12 | 15.78 | 24 | 30598 | 85028 | 29836828 |
Procedural haemorrhage | 31.47 | 15.78 | 23 | 30599 | 2315 | 29919541 |
Dyskinesia | 31.23 | 15.78 | 69 | 30553 | 21765 | 29900091 |
Resuscitation | 31.14 | 15.78 | 18 | 30604 | 1214 | 29920642 |
Vomiting | 30.90 | 15.78 | 118 | 30504 | 219700 | 29702156 |
Drug use disorder | 30.84 | 15.78 | 26 | 30596 | 3222 | 29918634 |
Influenza | 30.77 | 15.78 | 4 | 30618 | 43394 | 29878462 |
Delirium | 30.33 | 15.78 | 101 | 30521 | 40530 | 29881326 |
Electrocardiogram QT prolonged | 30.32 | 15.78 | 93 | 30529 | 35742 | 29886114 |
PCO2 increased | 29.75 | 15.78 | 14 | 30608 | 616 | 29921240 |
Electrocardiogram ST-T segment elevation | 29.43 | 15.78 | 5 | 30617 | 0 | 29921856 |
Spinal muscular atrophy | 29.40 | 15.78 | 10 | 30612 | 184 | 29921672 |
Lactic acidosis | 29.26 | 15.78 | 84 | 30538 | 31129 | 29890727 |
Chest pain | 29.19 | 15.78 | 47 | 30575 | 117580 | 29804276 |
Acidosis hyperchloraemic | 29.05 | 15.78 | 11 | 30611 | 279 | 29921577 |
Nodal rhythm | 28.74 | 15.78 | 18 | 30604 | 1405 | 29920451 |
Electrocardiogram T wave inversion | 28.57 | 15.78 | 21 | 30601 | 2133 | 29919723 |
Paraesthesia | 28.43 | 15.78 | 10 | 30612 | 54317 | 29867539 |
Mucosal ulceration | 28.14 | 15.78 | 15 | 30607 | 863 | 29920993 |
Chills | 28.03 | 15.78 | 147 | 30475 | 72191 | 29849665 |
Pneumomediastinum | 27.29 | 15.78 | 19 | 30603 | 1772 | 29920084 |
Myoglobin blood increased | 27.27 | 15.78 | 19 | 30603 | 1774 | 29920082 |
Chromaturia | 27.22 | 15.78 | 50 | 30572 | 13815 | 29908041 |
Torsade de pointes | 26.98 | 15.78 | 35 | 30587 | 7155 | 29914701 |
Atrioventricular block complete | 26.85 | 15.78 | 38 | 30584 | 8439 | 29913417 |
Local anaesthetic systemic toxicity | 26.54 | 15.78 | 9 | 30613 | 164 | 29921692 |
Suicidal ideation | 26.41 | 15.78 | 3 | 30619 | 36111 | 29885745 |
Subcutaneous emphysema | 26.36 | 15.78 | 15 | 30607 | 982 | 29920874 |
Locked-in syndrome | 26.25 | 15.78 | 10 | 30612 | 258 | 29921598 |
Muscle spasms | 26.19 | 15.78 | 17 | 30605 | 64821 | 29857035 |
Syncope | 26.06 | 15.78 | 29 | 30593 | 84874 | 29836982 |
Cellulitis | 25.55 | 15.78 | 8 | 30614 | 46776 | 29875080 |
Pseudocholinesterase deficiency | 25.49 | 15.78 | 6 | 30616 | 25 | 29921831 |
Suspected product contamination | 25.15 | 15.78 | 7 | 30615 | 63 | 29921793 |
Disseminated intravascular coagulation | 25.13 | 15.78 | 64 | 30558 | 22107 | 29899749 |
Systemic inflammatory response syndrome | 24.78 | 15.78 | 32 | 30590 | 6514 | 29915342 |
Trismus | 24.68 | 15.78 | 20 | 30602 | 2345 | 29919511 |
Unevaluable event | 24.61 | 15.78 | 80 | 30542 | 31705 | 29890151 |
Electrocardiogram abnormal | 24.20 | 15.78 | 30 | 30592 | 5862 | 29915994 |
Spinal cord infarction | 24.12 | 15.78 | 9 | 30613 | 219 | 29921637 |
Generalised tonic-clonic seizure | 23.80 | 15.78 | 58 | 30564 | 19493 | 29902363 |
Unresponsive to stimuli | 23.70 | 15.78 | 70 | 30552 | 26349 | 29895507 |
Brain death | 23.67 | 15.78 | 20 | 30602 | 2486 | 29919370 |
Obstructive airways disorder | 23.52 | 15.78 | 37 | 30585 | 9022 | 29912834 |
Pruritus | 23.42 | 15.78 | 54 | 30568 | 118150 | 29803706 |
Ventricular extrasystoles | 23.32 | 15.78 | 42 | 30580 | 11432 | 29910424 |
Hypotonia | 23.28 | 15.78 | 32 | 30590 | 6916 | 29914940 |
Sedation complication | 23.27 | 15.78 | 13 | 30609 | 821 | 29921035 |
Heparin-induced thrombocytopenia | 23.06 | 15.78 | 28 | 30594 | 5355 | 29916501 |
Coronary artery disease | 23.01 | 15.78 | 11 | 30611 | 49701 | 29872155 |
Conversion disorder | 23.00 | 15.78 | 10 | 30612 | 365 | 29921491 |
Stomatitis | 22.98 | 15.78 | 5 | 30617 | 37274 | 29884582 |
Hepatitis fulminant | 22.86 | 15.78 | 24 | 30598 | 3917 | 29917939 |
Long QT syndrome | 22.82 | 15.78 | 19 | 30603 | 2314 | 29919542 |
Oropharyngeal discomfort | 22.80 | 15.78 | 16 | 30606 | 1511 | 29920345 |
Unwanted awareness during anaesthesia | 22.76 | 15.78 | 6 | 30616 | 43 | 29921813 |
Weight bearing difficulty | 22.69 | 15.78 | 13 | 30609 | 862 | 29920994 |
Nystagmus | 22.68 | 15.78 | 25 | 30597 | 4313 | 29917543 |
Suspected product quality issue | 22.63 | 15.78 | 8 | 30614 | 166 | 29921690 |
Post-injection delirium sedation syndrome | 22.55 | 15.78 | 10 | 30612 | 383 | 29921473 |
Blood catecholamines increased | 22.28 | 15.78 | 5 | 30617 | 16 | 29921840 |
Hyperventilation | 22.02 | 15.78 | 19 | 30603 | 2430 | 29919426 |
Periorbital swelling | 21.70 | 15.78 | 8 | 30614 | 188 | 29921668 |
Neuromyopathy | 21.42 | 15.78 | 13 | 30609 | 959 | 29920897 |
Myocardial infarction | 21.35 | 15.78 | 62 | 30560 | 125563 | 29796293 |
Acute pulmonary oedema | 21.35 | 15.78 | 32 | 30590 | 7483 | 29914373 |
Inappropriate schedule of product administration | 21.33 | 15.78 | 7 | 30615 | 39721 | 29882135 |
Recurrence of neuromuscular blockade | 21.15 | 15.78 | 7 | 30615 | 118 | 29921738 |
Drug intolerance | 21.00 | 15.78 | 10 | 30612 | 45281 | 29876575 |
Air embolism | 20.88 | 15.78 | 7 | 30615 | 123 | 29921733 |
Seizure | 20.88 | 15.78 | 172 | 30450 | 98303 | 29823553 |
Priapism | 20.86 | 15.78 | 25 | 30597 | 4718 | 29917138 |
Bronchitis | 20.82 | 15.78 | 7 | 30615 | 39118 | 29882738 |
Dialysis | 20.77 | 15.78 | 39 | 30583 | 10957 | 29910899 |
Depression | 20.72 | 15.78 | 38 | 30584 | 90399 | 29831457 |
Hypothermia | 20.70 | 15.78 | 36 | 30586 | 9531 | 29912325 |
Migraine with aura | 20.60 | 15.78 | 10 | 30612 | 472 | 29921384 |
Renal impairment | 20.59 | 15.78 | 152 | 30470 | 84032 | 29837824 |
Electrocardiogram ST segment depression | 20.58 | 15.78 | 18 | 30604 | 2344 | 29919512 |
Neutrophil count decreased | 20.26 | 15.78 | 9 | 30613 | 42445 | 29879411 |
Chronic obstructive pulmonary disease | 20.17 | 15.78 | 11 | 30611 | 46115 | 29875741 |
Mydriasis | 20.14 | 15.78 | 28 | 30594 | 6115 | 29915741 |
Continuous haemodiafiltration | 19.93 | 15.78 | 13 | 30609 | 1088 | 29920768 |
Premature recovery from anaesthesia | 19.89 | 15.78 | 4 | 30618 | 6 | 29921850 |
Clonus | 19.81 | 15.78 | 18 | 30604 | 2463 | 29919393 |
Diabetes mellitus | 19.79 | 15.78 | 9 | 30613 | 41856 | 29880000 |
Contusion | 19.68 | 15.78 | 4 | 30618 | 31276 | 29890580 |
Incorrect drug administration rate | 19.56 | 15.78 | 13 | 30609 | 1123 | 29920733 |
Depressed level of consciousness | 19.39 | 15.78 | 84 | 30538 | 38138 | 29883718 |
Musculoskeletal pain | 19.37 | 15.78 | 4 | 30618 | 30936 | 29890920 |
Capillary nail refill test abnormal | 19.20 | 15.78 | 5 | 30617 | 34 | 29921822 |
End-tidal CO2 increased | 19.16 | 15.78 | 4 | 30618 | 8 | 29921848 |
Respiratory tract infection bacterial | 19.16 | 15.78 | 10 | 30612 | 551 | 29921305 |
Laryngeal oedema | 18.90 | 15.78 | 20 | 30602 | 3294 | 29918562 |
Haemoglobin decreased | 18.89 | 15.78 | 57 | 30565 | 114041 | 29807815 |
Treatment failure | 18.81 | 15.78 | 6 | 30616 | 34673 | 29887183 |
Acute kidney injury | 18.78 | 15.78 | 388 | 30234 | 273454 | 29648402 |
Epistaxis | 18.68 | 15.78 | 16 | 30606 | 52965 | 29868891 |
Stress | 18.52 | 15.78 | 54 | 30568 | 20181 | 29901675 |
Abdominal pain upper | 18.50 | 15.78 | 22 | 30600 | 62529 | 29859327 |
Hypoglycaemia | 18.46 | 15.78 | 15 | 30607 | 50966 | 29870890 |
Systolic anterior motion of mitral valve | 18.38 | 15.78 | 5 | 30617 | 41 | 29921815 |
Hypocapnia | 18.19 | 15.78 | 6 | 30616 | 100 | 29921756 |
Pupil fixed | 18.08 | 15.78 | 15 | 30607 | 1817 | 29920039 |
Transcranial electrical motor evoked potential monitoring abnormal | 18.01 | 15.78 | 4 | 30618 | 12 | 29921844 |
Septic shock | 17.99 | 15.78 | 119 | 30503 | 63488 | 29858368 |
Palpitations | 17.87 | 15.78 | 6 | 30616 | 33567 | 29888289 |
Skin test negative | 17.77 | 15.78 | 5 | 30617 | 47 | 29921809 |
Hyperkalaemia | 17.77 | 15.78 | 122 | 30500 | 65888 | 29855968 |
Pulmonary embolism | 17.74 | 15.78 | 33 | 30589 | 78102 | 29843754 |
Dyspnoea exertional | 17.73 | 15.78 | 7 | 30615 | 35423 | 29886433 |
Fear of death | 17.66 | 15.78 | 10 | 30612 | 648 | 29921208 |
Therapeutic response prolonged | 17.66 | 15.78 | 3 | 30619 | 0 | 29921856 |
Light anaesthesia | 17.66 | 15.78 | 3 | 30619 | 0 | 29921856 |
Coma | 17.63 | 15.78 | 85 | 30537 | 40364 | 29881492 |
Congenital megaureter | 17.61 | 15.78 | 6 | 30616 | 111 | 29921745 |
Coagulopathy | 17.56 | 15.78 | 50 | 30572 | 18437 | 29903419 |
Respiratory alkalosis | 17.17 | 15.78 | 13 | 30609 | 1381 | 29920475 |
Blood pressure systolic decreased | 17.06 | 15.78 | 20 | 30602 | 3687 | 29918169 |
Hepatitis | 17.06 | 15.78 | 56 | 30566 | 22300 | 29899556 |
Renal failure | 16.97 | 15.78 | 204 | 30418 | 128762 | 29793094 |
Thyrotoxic crisis | 16.83 | 15.78 | 8 | 30614 | 360 | 29921496 |
Herpes zoster | 16.56 | 15.78 | 5 | 30617 | 29938 | 29891918 |
General physical health deterioration | 16.49 | 15.78 | 50 | 30572 | 99894 | 29821962 |
Cardiogenic shock | 16.40 | 15.78 | 46 | 30576 | 16815 | 29905041 |
Anaesthetic complication pulmonary | 16.40 | 15.78 | 4 | 30618 | 20 | 29921836 |
Electrocardiogram QRS complex prolonged | 16.33 | 15.78 | 21 | 30601 | 4256 | 29917600 |
Hypertransaminasaemia | 16.31 | 15.78 | 20 | 30602 | 3865 | 29917991 |
Upper airway obstruction | 16.19 | 15.78 | 9 | 30613 | 563 | 29921293 |
Myoglobinuria | 16.04 | 15.78 | 10 | 30612 | 774 | 29921082 |
Dysgeusia | 15.96 | 15.78 | 3 | 30619 | 24798 | 29897058 |
Periventricular haemorrhage neonatal | 15.79 | 15.78 | 4 | 30618 | 24 | 29921832 |
Hepatitis acute | 15.78 | 15.78 | 27 | 30595 | 7056 | 29914800 |
Source | Code | Description |
---|---|---|
ATC | N01AX10 | NERVOUS SYSTEM ANESTHETICS ANESTHETICS, GENERAL Other general anesthetics |
FDA EPC | N0000175681 | General Anesthetic |
MeSH PA | D000777 | Anesthetics |
MeSH PA | D018686 | Anesthetics, Intravenous |
MeSH PA | D002491 | Central Nervous System Agents |
MeSH PA | D002492 | Central Nervous System Depressants |
MeSH PA | D006993 | Hypnotics and Sedatives |
FDA PE | N0000175975 | General Anesthesia |
CHEBI has role | CHEBI:35623 | antiepileptic |
CHEBI has role | CHEBI:35717 | sedatives |
CHEBI has role | CHEBI:38877 | intravenous anesthetics |
CHEBI has role | CHEBI:48578 | free-radical scavenger |
CHEBI has role | CHEBI:50919 | antiemetico |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
General anesthesia | indication | 50697003 | |
Sedation in Intubated Patients | indication | ||
Sedation as Adjunct to Anesthesia | indication | ||
Apnea | contraindication | 1023001 | |
Asthenia | contraindication | 13791008 | |
Hypovolemia | contraindication | 28560003 | |
Low blood pressure | contraindication | 45007003 | |
Cerebral arteriosclerosis | contraindication | 65312002 | |
Decreased respiratory function | contraindication | 80954004 | |
Epilepsy | contraindication | 84757009 | DOID:1826 |
Myocardial dysfunction | contraindication | 233928007 | |
Disorder of lipid metabolism | contraindication | 267431006 | |
Hypoxia | contraindication | 389086002 |
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 10.8 | acidic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
GABA A receptor alpha-2/beta-2/gamma-2 | Ion channel | POSITIVE ALLOSTERIC MODULATOR | EC50 | 4.95 | CHEMBL | CHEMBL | |||
GABA-A receptor alpha-1/beta-3/gamma-2 | Ion channel | POSITIVE ALLOSTERIC MODULATOR | EC50 | 5.39 | CHEMBL | CHEMBL | |||
GABA-A receptor alpha-1/beta-2/gamma-2 | Ion channel | POSITIVE ALLOSTERIC MODULATOR | EC50 | 5.70 | CHEMBL | CHEMBL | |||
5-hydroxytryptamine receptor 2C | GPCR | Ki | 5.22 | DRUG MATRIX | |||||
Cytochrome P450 2C9 | Enzyme | IC50 | 4.91 | WOMBAT-PK | |||||
Carbonic anhydrase 1 | Enzyme | IC50 | 4.71 | WOMBAT-PK | |||||
Carbonic anhydrase 2 | Enzyme | IC50 | 4.01 | WOMBAT-PK | |||||
Fatty-acid amide hydrolase 1 | Enzyme | IC50 | 4.28 | WOMBAT-PK | |||||
Prostaglandin G/H synthase 1 | Enzyme | IC50 | 5.42 | DRUG MATRIX | |||||
Sodium-dependent noradrenaline transporter | Transporter | Ki | 5.03 | DRUG MATRIX | |||||
5-hydroxytryptamine receptor 2B | GPCR | Ki | 5.46 | DRUG MATRIX | |||||
Arachidonate 15-lipoxygenase | Enzyme | IC50 | 5.12 | DRUG MATRIX | |||||
Fatty-acid amide hydrolase 1 | Enzyme | IC50 | 4.85 | CHEMBL | |||||
GABA-A receptor; anion channel | Ion channel | IC50 | 5.40 | CHEMBL | |||||
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | Ion channel | BLOCKER | IC50 | 5.20 | IUPHAR |
ID | Source |
---|---|
4019500 | VUID |
N0000147620 | NUI |
D00549 | KEGG_DRUG |
4019500 | VANDF |
C0678120 | UMLSCUI |
CHEBI:44915 | CHEBI |
PFL | PDB_CHEM_ID |
CHEMBL526 | ChEMBL_ID |
4943 | PUBCHEM_CID |
D015742 | MESH_DESCRIPTOR_UI |
DB00818 | DRUGBANK_ID |
5464 | IUPHAR_LIGAND_ID |
5073 | INN_ID |
YI7VU623SF | UNII |
196459 | RXNORM |
14179 | MMSL |
5372 | MMSL |
65 | MMSL |
d00933 | MMSL |
003528 | NDDF |
387423006 | SNOMEDCT_US |
74674007 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-0209 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
Propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-0234 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
Propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-0248 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
Propofol Lipuro | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0264-4850 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | unapproved drug other | 3 sections |
PROPOFOL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0409-4699 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
Propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0591-2136 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 26 sections |
Propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0641-6194 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 24 sections |
Propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0641-6195 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 24 sections |
Propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0641-6196 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 24 sections |
Fresenius Propoven 2% | HUMAN PRESCRIPTION DRUG LABEL | 1 | 18124-027 | EMULSION | 20 mg | INTRAVENOUS | unapproved drug other | 2 sections |
propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 25021-608 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 27 sections |
Propofol Injectable Emulsion | HUMAN PRESCRIPTION DRUG LABEL | 1 | 43598-265 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 22 sections |
Propofol Injectable Emulsion | HUMAN PRESCRIPTION DRUG LABEL | 1 | 43598-548 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 22 sections |
Propofol Injectable Emulsion | HUMAN PRESCRIPTION DRUG LABEL | 1 | 43598-549 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 22 sections |
Propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50090-4569 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 27 sections |
PROPOFOL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51662-1293 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 14 sections |
PROPOFOL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51662-1470 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 14 sections |
PROPOFOL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 51662-1471 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 14 sections |
PROPOFOL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 52584-098 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 14 sections |
Diprivan | HUMAN PRESCRIPTION DRUG LABEL | 1 | 52584-269 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | NDA | 12 sections |
Propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 52584-699 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 14 sections |
Diprivan | Human Prescription Drug Label | 1 | 63323-269 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | NDA | 14 sections |
Diprivan | Human Prescription Drug Label | 1 | 63323-269 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | NDA | 14 sections |
Diprivan | Human Prescription Drug Label | 1 | 63323-269 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | NDA | 14 sections |
Diprivan | Human Prescription Drug Label | 1 | 63323-269 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | NDA | 14 sections |
Fresenius Propoven 2% | HUMAN PRESCRIPTION DRUG LABEL | 1 | 65219-427 | EMULSION | 20 mg | INTRAVENOUS | unapproved drug other | 2 sections |
Diprivan | Human Prescription Drug Label | 1 | 65219-800 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | NDA | 14 sections |
Propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 72572-583 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 24 sections |
Propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 72572-584 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 24 sections |
Propofol | HUMAN PRESCRIPTION DRUG LABEL | 1 | 72572-585 | INJECTION, EMULSION | 10 mg | INTRAVENOUS | ANDA | 24 sections |