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2022 Update-Veterinary Drugs & Uses
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
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Smart API
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L1000
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FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
propentofylline 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
N-methylated xanthine derivatives
2296
55242-55-2
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
propentofylline
propentophylline
Molecular weight: 306.37
Formula: C15H22N4O3
CLOGP: 1.17
LIPINSKI: 0
HAC: 7
HDO: 0
TPSA: 75.51
ALOGS: -2.05
ROTB: 7
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
N06BC02
NERVOUS SYSTEM
PSYCHOANALEPTICS
PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
Xanthine derivatives
MeSH PA
D002491
Central Nervous System Agents
MeSH PA
D018696
Neuroprotective Agents
MeSH PA
D020011
Protective Agents
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
1.63
Basic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Acetylcholinesterase
Enzyme
P22303
ACES_HUMAN
IC50
5.19
CHEMBL
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External reference:
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entries
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ID
Source
POY
PDB_CHEM_ID
008166
NDDF
34644
RXNORM
4938
PUBCHEM_CID
5005
INN_ID
5RTA398U4H
UNII
C0072171
UMLSCUI
C032114
MESH_SUPPLEMENTAL_RECORD_UI
CHEBI:32061
CHEBI
CHEMBL1079905
ChEMBL_ID
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Pharmaceutical products:
None
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Structure 🔎
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propentofylline