Molfile
Inchi
Smiles
Synonyms:
-
primaquine
-
primachin
-
primaquin
-
dl-Primaquine
-
(+/-)-Primaquine
-
primaquine phosphate
-
primaquine diphosphate
|
An aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. Adverse effects include anemias and GI disturbances. (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
- Molecular weight: 259.35
- Formula: C15H21N3O
- CLOGP: 2.60
- LIPINSKI: 0
- HAC: 4
- HDO: 2
- TPSA: 60.17
- ALOGS: -3.66
- ROTB: 6
- Status: OFP
Legend: OFP - off patent OFM - off market ONP - on patent
|