prifinium 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
quaternary ammonium compounds 2264 4630-95-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • prifinium bromide
  • pyrodifenium bromide
  • prifinium
  • Molecular weight: 306.47
  • Formula: C22H28N
  • CLOGP: 1.35
  • LIPINSKI: 0
  • HAC: 1
  • HDO: 0
  • TPSA:
  • ALOGS: -6.36
  • ROTB: 4

Drug dosage:

None

ADMET properties:

PropertyValueReference
Vd (Volume of distribution) 1.87 L/kg Lombardo F, Berellini G, Obach RS
CL (Clearance) 12.50 mL/min/kg Lombardo F, Berellini G, Obach RS
t_half (Half-life) 2.13 hours Lombardo F, Berellini G, Obach RS

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A03AB18 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS
Synthetic anticholinergics, quaternary ammonium compounds

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01377 KEGG_DRUG
10236-81-4 SECONDARY_CAS_RN
CHEBI:32052 CHEBI
CHEMBL1229214 ChEMBL_ID
CHEMBL1213353 ChEMBL_ID
C084641 MESH_SUPPLEMENTAL_RECORD_UI
DB13254 DRUGBANK_ID
3C7TTK1K7K UNII
236174 RXNORM
005292 NDDF
005293 NDDF
C0771424 UMLSCUI
2499 INN_ID
4905 PUBCHEM_CID

Pharmaceutical products:

None