pridinol Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
2263 511-45-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • pridinol
  • pridinol methanesulfonate salt
  • pridinol methanesulfonate
antispasmodic & muscle relaxant; RN given refers to parent cpd; structure in Merck Index, 9th ed, #7539
  • Molecular weight: 295.43
  • Formula: C20H25NO
  • CLOGP: 4.07
  • LIPINSKI: 0
  • HAC: 2
  • HDO: 1
  • TPSA: 23.47
  • ALOGS: -4.19
  • ROTB: 5

Drug dosage:

DoseUnitRoute
6 mg O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
ATC M03BX03 MUSCULO-SKELETAL SYSTEM
MUSCLE RELAXANTS
MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS
Other centrally acting agents
CHEBI has role CHEBI:51371 muscle relaxant
CHEBI has role CHEBI:48407 antiparkinson drug

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.8 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Muscarinic acetylcholine receptor M3 GPCR Ki 8.19 PDSP
Muscarinic acetylcholine receptor M1 GPCR Ki 8.80 PDSP
Muscarinic acetylcholine receptor M5 GPCR Ki 7.80 PDSP
Muscarinic acetylcholine receptor M4 GPCR Ki 8.59 PDSP
Muscarinic acetylcholine receptor M2 GPCR Ki 8.15 PDSP

External reference:

IDSource
C0071968 UMLSCUI
D08418 KEGG_DRUG
34479 RXNORM
006583 NDDF
9E75Q6SUUB UNII
1320 INN_ID
CHEBI:75247 CHEBI
CHEMBL404215 ChEMBL_ID
4904 PUBCHEM_CID
CHEMBL1528011 ChEMBL_ID
DB13642 DRUGBANK_ID
C009185 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None