prednisolone valerate acetate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| prednisone and prednisolone derivatives | 2252 | 72064-79-0 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
topical steroid used for skin disease therapy
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| S (Water solubility) | 0.22 mg/mL | Bocci G, Oprea TI, Benet LZ |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| FDA MoA | N0000175450 | Corticosteroid Hormone Receptor Agonists |
| FDA EPC | N0000175576 | Corticosteroid |
| MeSH PA | D000893 | Anti-Inflammatory Agents |
| MeSH PA | D000970 | Antineoplastic Agents |
| MeSH PA | D018931 | Antineoplastic Agents, Hormonal |
| MeSH PA | D005938 | Glucocorticoids |
| MeSH PA | D006728 | Hormones |
| CHEBI has role | CHEBI:35472 | anti-inflammatory drugs |
| CHEBI has role | CHEBI:35610 | antineoplastic agents |
| CHEBI has role | CHEBI:35703 | Xenobiotic |
| CHEBI has role | CHEBI:35705 | immunosuppressive agents |
| CHEBI has role | CHEBI:37962 | adrenergic agents |
| CHEBI has role | CHEBI:49103 | drug metabolites |
| CHEBI has role | CHEBI:78298 | environmental contaminants |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 13.19 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D03301 | KEGG_DRUG |
| 4017988 | VANDF |
| C1882445 | UMLSCUI |
| CHEBI:135785 | CHEBI |
| CHEBI:8378 | CHEBI |
| TUA | PDB_CHEM_ID |
| CHEMBL1697848 | ChEMBL_ID |
| C023724 | MESH_SUPPLEMENTAL_RECORD_UI |
| 2JB27QJW3D | UNII |
| 5284612 | PUBCHEM_CID |
| DB00860 | DRUGBANK_ID |
| 8638 | RXNORM |
| 5347 | MMSL |
| 59710 | MMSL |
| d00084 | MMSL |
| 002155 | NDDF |
| 116601002 | SNOMEDCT_US |
| 52388000 | SNOMEDCT_US |
| C0032950 | UMLSCUI |
| 535 | INN_ID |
| 5755 | PUBCHEM_CID |
| D011239 | MESH_DESCRIPTOR_UI |
Pharmaceutical products:
None