polysorbate 80 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
2227 9005-65-6

Description:

MoleculeDescription

Synonyms:

  • polysorbate 80
  • polyethoxylated sorbitan monooleate
Sorbitan mono-9-octadecanoate poly(oxy-1,2-ethanediyl) derivatives; complex mixtures of polyoxyethylene ethers used as emulsifiers or dispersing agents in pharmaceuticals.
  • Molecular weight:
  • Formula: C24H44O6(C2H4O)x(C2H4O)w(C2H4O)y(C2H4O)z
  • CLOGP:
  • LIPINSKI: None
  • HAC: None
  • HDO: None
  • TPSA:
  • ALOGS:
  • ROTB: None

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D005079 Excipients
MeSH PA D010592 Pharmaceutic Aids
MeSH PA D014677 Pharmaceutical Vehicles
MeSH PA D013501 Surface-Active Agents
CHEBI has role CHEBI:38828 non-ionic surfactant

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Tear film insufficiency indication 46152009
Keratoconjunctivitis sicca off-label use 302896008 DOID:12895




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4017948 VUID
N0000178958 NUI
D01067 KEGG_DRUG
4017948 VANDF
C0032601 UMLSCUI
CHEBI:53426 CHEBI
VCG PDB_CHEM_ID
CHEMBL1697847 ChEMBL_ID
D011136 MESH_DESCRIPTOR_UI
DB11063 DRUGBANK_ID
6OZP39ZG8H UNII
8560 RXNORM
NOCODE MMSL
009865 NDDF
255899003 SNOMEDCT_US
411257002 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
REFRESH OPTIVE Advanced HUMAN OTC DRUG LABEL 3 0023-4307 SOLUTION/ DROPS 5 mg OPHTHALMIC OTC MONOGRAPH FINAL 12 sections
REFRESH OPTIVE Advanced HUMAN OTC DRUG LABEL 3 0023-4491 SOLUTION/ DROPS 5 mg OPHTHALMIC OTC MONOGRAPH FINAL 11 sections
REFRESH OPTIVE Mega-3 HUMAN OTC DRUG LABEL 3 0023-5773 SOLUTION/ DROPS 5 mg OPHTHALMIC OTC monograph final 10 sections
Refresh Digital HUMAN OTC DRUG LABEL 3 0023-6952 SOLUTION/ DROPS 5 mg OPHTHALMIC OTC MONOGRAPH FINAL 10 sections
Refresh Digital PF HUMAN OTC DRUG LABEL 3 0023-6954 SOLUTION/ DROPS 5 mg OPHTHALMIC OTC MONOGRAPH FINAL 10 sections
REFRESH OPTIVE Mega-3 HUMAN OTC DRUG LABEL 3 0023-7151 SOLUTION/ DROPS 5 mg OPHTHALMIC OTC monograph final 10 sections
Endura HUMAN PRESCRIPTION DRUG LABEL 2 0023-9235 SOLUTION/ DROPS 1 g OPHTHALMIC Export only 1 sections
IV Solution Stabilizer HUMAN PRESCRIPTION DRUG LABEL 1 0310-4715 SOLUTION 6.50 mg INTRAVENOUS BLA 28 sections
RohtoCool Relief HUMAN OTC DRUG LABEL 2 10742-8141 LIQUID 2 mg OPHTHALMIC OTC monograph final 12 sections
RohtoCool HUMAN OTC DRUG LABEL 2 10742-8142 LIQUID 2 mg OPHTHALMIC OTC monograph final 12 sections
Rohto Beauty Secret HUMAN OTC DRUG LABEL 2 10742-8145 LIQUID 2 mg OPHTHALMIC OTC monograph final 12 sections
RohtoMax Strength HUMAN OTC DRUG LABEL 2 10742-8158 LIQUID 2 mg OPHTHALMIC OTC monograph final 12 sections
RohtoCool Max HUMAN OTC DRUG LABEL 2 10742-8159 LIQUID 2 mg OPHTHALMIC OTC monograph final 12 sections
Avitears HUMAN OTC DRUG LABEL 1 49869-002 SOLUTION/ DROPS 10 mg TOPICAL OTC monograph final 9 sections
Viva HUMAN OTC DRUG LABEL 1 54891-001 SOLUTION/ DROPS 100 mg OPHTHALMIC OTC monograph final 8 sections
Clear Eyes Complete 7 Symptom Relief HUMAN OTC DRUG LABEL 4 67172-595 LIQUID 1.25 mL OPHTHALMIC OTC MONOGRAPH FINAL 14 sections
Clear Eyes Complete 7 Sympton Relief HUMAN OTC DRUG LABEL 4 67172-707 LIQUID 1.25 mg OPHTHALMIC OTC MONOGRAPH FINAL 14 sections
IV STABILIZER HUMAN PRESCRIPTION DRUG LABEL 1 73380-4715 SOLUTION 6.50 mg INTRAVENOUS BLA 31 sections
i-Drops ARTIFICIAL TEARS HUMAN OTC DRUG LABEL 4 73921-009 SOLUTION/ DROPS 5 mg OPHTHALMIC OTC monograph final 11 sections
Eyellic Eye Drops (Sterile) HUMAN OTC DRUG LABEL 4 77684-899 SOLUTION/ DROPS 0.50 g OPHTHALMIC export only 14 sections