aminomethylbenzoic acid 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
22 56-91-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • p-aminomethylbenzoic acid
  • para-aminomethylbenzoic acid
  • gumbix
  • 4-aminomethyl-benzoic acid
  • 4-aminomethylbenzoic acid
  • aminomethylbenzoic acid
  • benzylamine-4-carboxylic acid
  • p-carboxybenzylamine
  • Molecular weight: 151.17
  • Formula: C8H9NO2
  • CLOGP: -1.43
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 2
  • TPSA: 63.32
  • ALOGS: -1.62
  • ROTB: 2

Drug dosage:

DoseUnitRoute
0.25 g O

ADMET properties:

None

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
kinase-safety-class ACVR2A,ACVR2B,AURKA,AXL,BRAF,BTK,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GRK3,GSK3B,IKBKB,ITK,JAK2,MAP2K6,MAP3K21,MAP3K7,MAPK12,MAPK7,MAPKAPK2,NTRK2,PDK1,PDK2,PDK4,PIK3CB,PIM2,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ZAP70 44
kinase-selectivity-class ACVR2A,ACVR2B,AXL,BRAF,CDK9,DYRK1B,EIF2AK3,EPHB4,GRK2,MAPK7,MARK4,PRKDC,SIK2,STK33,TEK,TTK,UHMK1,ULK2 18
pfas-class PFAS structural alert (1 = True, 0 = False) 0

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC B02AA03 BLOOD AND BLOOD FORMING ORGANS
ANTIHEMORRHAGICS
ANTIFIBRINOLYTICS
Amino acids
MeSH PA D000933 Antifibrinolytic Agents
MeSH PA D003029 Coagulants
MeSH PA D004791 Enzyme Inhibitors
MeSH PA D006401 Hematologic Agents
MeSH PA D006490 Hemostatics
MeSH PA D011480 Protease Inhibitors

Related Drugs by ATC class:

B02AA Amino acids 2 drugs
aminocaproic acidtranexamic acid

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.94 acidic
pKa2 9.67 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07568 KEGG_DRUG
14852 RXNORM
C0048045 UMLSCUI
CHEBI:134774 CHEBI
CHEMBL328875 ChEMBL_ID
DB13244 DRUGBANK_ID
C015668 MESH_SUPPLEMENTAL_RECORD_UI
68WG9JKC7L UNII
65526 PUBCHEM_CID
4AZ PDB_CHEM_ID
007158 NDDF

Pharmaceutical products:

None