perflubron 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
perfluorinated compounds used as blood substitutes and/or diagnostic agents 2102 423-55-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • perflubron
  • perfluoroctyl bromide
  • perfluorooctyl bromide
potential anti-obesity compound; reduces food adsorption; 8-carbon perfluorocarbon radiopaque compound; an oral contrast agent for use with MRI to enhance delineation of the bowel distinguishing it from adjacent organs
  • Molecular weight: 498.97
  • Formula: C8BrF17
  • CLOGP: 4.54
  • LIPINSKI: 0
  • HAC: 0
  • HDO: 0
  • TPSA:
  • ALOGS: -4.20
  • ROTB: 7
  • Status: OFM
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Aug. 13, 1993 FDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC V08CX01 VARIOUS
CONTRAST MEDIA
MAGNETIC RESONANCE IMAGING CONTRAST MEDIA
Other magnetic resonance imaging contrast media
MeSH PA D019440 Anti-Obesity Agents
MeSH PA D003287 Contrast Media
MeSH PA D064907 Diagnostic Uses of Chemicals
MeSH PA D011838 Radiation-Sensitizing Agents
CHEBI has role CHEBI:37338 contrast media
CHEBI has role CHEBI:38849 artificial blood

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D05439 KEGG_DRUG
4020838 VANDF
C0162922 UMLSCUI
CHEBI:38803 CHEBI
CHEMBL1200866 ChEMBL_ID
DB05791 DRUGBANK_ID
C003072 MESH_SUPPLEMENTAL_RECORD_UI
6903 INN_ID
Q1D0Q7R4D9 UNII
9873 PUBCHEM_CID

Pharmaceutical products:

None