pentetic acid 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 2092 | 67-43-6 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
An iron chelating agent with properties like EDETIC ACID. DTPA has also been used as a chelator for other metals, such as plutonium.
|
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| MeSH PA | D000931 | Antidotes |
| MeSH PA | D002614 | Chelating Agents |
| MeSH PA | D007502 | Iron Chelating Agents |
| MeSH PA | D020011 | Protective Agents |
| MeSH PA | D064449 | Sequestering Agents |
| FDA MoA | N0000175962 | Lead Chelating Activity |
| FDA EPC | N0000175963 | Lead Chelator |
| CHEBI has role | CHEBI:166831 | copper chelator |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 0.82 | acidic |
| pKa2 | 1.26 | acidic |
| pKa3 | 1.84 | acidic |
| pKa4 | 2.15 | acidic |
| pKa5 | 2.75 | acidic |
| pKa6 | 10.13 | Basic |
| pKa7 | 9.11 | Basic |
| pKa8 | 4.37 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| 4019580 | VUID |
| N0000147679 | NUI |
| D05422 | KEGG_DRUG |
| 4018190 | VANDF |
| 4019580 | VANDF |
| C0013254 | UMLSCUI |
| CHEBI:35739 | CHEBI |
| CHEMBL780 | ChEMBL_ID |
| D004369 | MESH_DESCRIPTOR_UI |
| DB14007 | DRUGBANK_ID |
| 3053 | PUBCHEM_CID |
| 6596 | INN_ID |
| 7A314HQM0I | UNII |
| 3690 | RXNORM |
| 194369 | MMSL |
| 28970 | MMSL |
| d07922 | MMSL |
| 006655 | NDDF |
| 009768 | NDDF |
| 429352009 | SNOMEDCT_US |
| 429461005 | SNOMEDCT_US |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| DRAXIMAGE DTPA | HUMAN PRESCRIPTION DRUG LABEL | 1 | 65174-288 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 20 mg | INTRAVENOUS | NDA | 21 sections |
| DRAXIMAGE DTPA | HUMAN PRESCRIPTION DRUG LABEL | 1 | 65174-288 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 20 mg | INTRAVENOUS | NDA | 21 sections |
| DRAXIMAGE DTPA | HUMAN PRESCRIPTION DRUG LABEL | 1 | 65174-288 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 20 mg | INTRAVENOUS | NDA | 21 sections |
| DRAXIMAGE DTPA | HUMAN PRESCRIPTION DRUG LABEL | 1 | 65174-288 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 20 mg | INTRAVENOUS | NDA | 21 sections |