pentaerythritol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
2085 115-77-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • pentaerythritol
  • 1,1,1-Tris(hydroxymethyl)ethanol
  • monopentaerythritol
  • Tetra(hydroxymethyl)methane
  • tetramethylolmethane
  • pentaerithrityl
  • Molecular weight: 136.15
  • Formula: C5H12O4
  • CLOGP: -0.93
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 4
  • TPSA: 80.92
  • ALOGS: 0.55
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC A06AD14 ALIMENTARY TRACT AND METABOLISM
DRUGS FOR CONSTIPATION
DRUGS FOR CONSTIPATION
Osmotically acting laxatives
CHEBI has role CHEBI:50503 laxante
CHEBI has role CHEBI:79314 flame retardants

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Suicidal thoughts contraindication 6471006
Alcoholism contraindication 7200002
Hyperammonemia contraindication 9360008
Hepatic encephalopathy contraindication 13920009 DOID:13413
Lowered convulsive threshold contraindication 19260006
Depressive disorder contraindication 35489007
Hepatic failure contraindication 59927004
Poisoning by phenobarbital contraindication 64921004
Substance abuse contraindication 66214007
Hepatic coma contraindication 72836002 DOID:12550
Sleep apnea contraindication 73430006 DOID:0050847
Chronic idiopathic constipation contraindication 82934008
Open-angle glaucoma contraindication 84494001 DOID:1067
Kidney disease contraindication 90708001 DOID:557
Seizure disorder contraindication 128613002
Acute intermittent porphyria contraindication 234422006 DOID:3890
Disease of liver contraindication 235856003 DOID:409
Bladder outflow obstruction contraindication 236645006
Benign prostatic hyperplasia contraindication 266569009
Dyspnea contraindication 267036007
Retention of urine contraindication 267064002
Anemia contraindication 271737000 DOID:2355
Pregnancy, function contraindication 289908002
Thrombocytopenic disorder contraindication 302215000 DOID:1588
Neutropenic disorder contraindication 303011007 DOID:1227
Angle-closure glaucoma contraindication 392291006 DOID:13550
Breastfeeding (mother) contraindication 413712001
Porphyria contraindication 418470004




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
C0070276 UMLSCUI
CHEBI:134760 CHEBI
8285 PUBCHEM_CID
DB13526 DRUGBANK_ID
C008783 MESH_SUPPLEMENTAL_RECORD_UI
SU420W1S6N UNII
33055 RXNORM
005477 NDDF
3SY PDB_CHEM_ID

Pharmaceutical products:

None