paramethasone acetate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| prednisone and prednisolone derivatives | 2060 | 1597-82-6 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
A glucocorticoid with the general properties of corticosteroids. It has been used by mouth in the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-retaining properties makes it less suitable than HYDROCORTISONE with supplementary FLUDROCORTISONE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p737)
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 4 | mg | O |
| 4 | mg | P |
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA | LILLY |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | H02AB05 | SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS CORTICOSTEROIDS FOR SYSTEMIC USE CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN Glucocorticoids |
| MeSH PA | D000893 | Anti-Inflammatory Agents |
| MeSH PA | D005938 | Glucocorticoids |
| MeSH PA | D006728 | Hormones |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 12.76 | acidic |
| pKa2 | 13.41 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| 4017502 | VUID |
| N0000179209 | NUI |
| D01229 | KEGG_DRUG |
| 4017502 | VANDF |
| 4019876 | VANDF |
| C0070073 | UMLSCUI |
| CHEBI:31963 | CHEBI |
| CHEBI:7922 | CHEBI |
| CHEMBL1200342 | ChEMBL_ID |
| DB14657 | DRUGBANK_ID |
| C032128 | MESH_SUPPLEMENTAL_RECORD_UI |
| 8X50N88ZDP | UNII |
| 443928 | PUBCHEM_CID |
| DB01384 | DRUGBANK_ID |
| 32895 | RXNORM |
| 002167 | NDDF |
| 004946 | NDDF |
| 116604005 | SNOMEDCT_US |
| 116605006 | SNOMEDCT_US |
| 17554004 | SNOMEDCT_US |
| C0030454 | UMLSCUI |
| CHEMBL1579 | ChEMBL_ID |
| 1096 | INN_ID |
| 53-33-8 | SECONDARY_CAS_RN |
| 5875 | PUBCHEM_CID |
| D010248 | MESH_DESCRIPTOR_UI |
| VFC6ZX3584 | UNII |
Pharmaceutical products:
None