Stem definition | Drug id | CAS RN |
---|---|---|
antiulcer, benzimidazole derivatives | 2054 | 102625-70-7 |
Dose | Unit | Route |
---|---|---|
40 | mg | O |
40 | mg | P |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 1 | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 0 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 1.74 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
Vd (Volume of distribution) | 0.17 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 2.20 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.02 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 1.90 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
Feb. 2, 2000 | FDA | WYETH PHARMS INC |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
General physical health deterioration | 749.76 | 9.93 | 3156 | 477469 | 166854 | 55644588 |
Toxicity to various agents | 545.57 | 9.93 | 669 | 479956 | 223895 | 55587547 |
Chronic kidney disease | 544.81 | 9.93 | 1147 | 479478 | 40909 | 55770533 |
Completed suicide | 522.79 | 9.93 | 244 | 480381 | 133589 | 55677853 |
Drug ineffective | 399.10 | 9.93 | 5497 | 475128 | 913492 | 54897950 |
Folliculitis | 344.97 | 9.93 | 1144 | 479481 | 53835 | 55757607 |
Muscle injury | 338.88 | 9.93 | 1103 | 479522 | 51397 | 55760045 |
Irritable bowel syndrome | 309.13 | 9.93 | 1281 | 479344 | 67177 | 55744265 |
Exposure during pregnancy | 293.64 | 9.93 | 443 | 480182 | 135899 | 55675543 |
Haematochezia | 275.41 | 9.93 | 911 | 479714 | 42807 | 55768635 |
Lower respiratory tract infection | 241.15 | 9.93 | 1743 | 478882 | 113051 | 55698391 |
Impaired healing | 233.68 | 9.93 | 1403 | 479222 | 85438 | 55726004 |
Sleep disorder due to general medical condition, insomnia type | 230.52 | 9.93 | 854 | 479771 | 42484 | 55768958 |
Product prescribing error | 220.42 | 9.93 | 560 | 480065 | 22626 | 55788816 |
Death | 199.89 | 9.93 | 1907 | 478718 | 339519 | 55471923 |
Acute kidney injury | 199.86 | 9.93 | 3024 | 477601 | 237739 | 55573703 |
Device expulsion | 193.97 | 9.93 | 18 | 480607 | 30431 | 55781011 |
Abdominal pain upper | 185.51 | 9.93 | 2332 | 478293 | 175981 | 55635461 |
Injection site pain | 183.86 | 9.93 | 459 | 480166 | 116659 | 55694783 |
Injection site erythema | 180.24 | 9.93 | 238 | 480387 | 77210 | 55734232 |
Stomatitis | 178.33 | 9.93 | 1694 | 478931 | 119116 | 55692326 |
Anaemia | 175.69 | 9.93 | 3234 | 477391 | 264277 | 55547165 |
Blister | 172.39 | 9.93 | 1550 | 479075 | 107337 | 55704105 |
Gastrointestinal disorder | 171.18 | 9.93 | 1590 | 479035 | 111112 | 55700330 |
Off label use | 170.68 | 9.93 | 3539 | 477086 | 552641 | 55258801 |
End stage renal disease | 169.37 | 9.93 | 234 | 480391 | 5877 | 55805565 |
Peripheral swelling | 168.08 | 9.93 | 2877 | 477748 | 231849 | 55579593 |
Renal injury | 162.82 | 9.93 | 281 | 480344 | 8606 | 55802836 |
Ill-defined disorder | 162.34 | 9.93 | 1072 | 479553 | 67471 | 55743971 |
Abortion spontaneous | 161.34 | 9.93 | 86 | 480539 | 43667 | 55767775 |
Intentional overdose | 159.86 | 9.93 | 208 | 480417 | 67909 | 55743533 |
Injection site reaction | 158.26 | 9.93 | 133 | 480492 | 53114 | 55758328 |
Dyspnoea | 153.90 | 9.93 | 6350 | 474275 | 586227 | 55225215 |
Hyponatraemia | 152.10 | 9.93 | 1435 | 479190 | 100704 | 55710738 |
Hypomagnesaemia | 151.08 | 9.93 | 514 | 480111 | 24501 | 55786941 |
Drug hypersensitivity | 140.90 | 9.93 | 1586 | 479039 | 273619 | 55537823 |
Maternal exposure during pregnancy | 140.28 | 9.93 | 994 | 479631 | 188559 | 55622883 |
Muscle spasticity | 138.46 | 9.93 | 430 | 480195 | 19530 | 55791912 |
Confusional state | 136.74 | 9.93 | 2517 | 478108 | 205638 | 55605804 |
Treatment failure | 135.31 | 9.93 | 875 | 479750 | 169517 | 55641925 |
Rheumatoid arthritis | 126.61 | 9.93 | 2403 | 478222 | 380201 | 55431241 |
Systemic infection | 116.93 | 9.93 | 142 | 480483 | 3127 | 55808315 |
Drug abuse | 116.50 | 9.93 | 252 | 480373 | 67358 | 55744084 |
Sinusitis | 114.76 | 9.93 | 2345 | 478280 | 195236 | 55616206 |
Wrong technique in product usage process | 112.12 | 9.93 | 203 | 480422 | 57965 | 55753477 |
Night sweats | 109.62 | 9.93 | 664 | 479961 | 40549 | 55770893 |
Ear pain | 109.36 | 9.93 | 538 | 480087 | 30352 | 55781090 |
Product dose omission issue | 109.10 | 9.93 | 1169 | 479456 | 203584 | 55607858 |
Asthenia | 108.25 | 9.93 | 3757 | 476868 | 339216 | 55472226 |
Body temperature increased | 107.72 | 9.93 | 577 | 480048 | 33665 | 55777777 |
Injection site swelling | 104.38 | 9.93 | 131 | 480494 | 43447 | 55767995 |
Labelled drug-drug interaction medication error | 103.09 | 9.93 | 273 | 480352 | 11313 | 55800129 |
Pruritus | 100.80 | 9.93 | 3472 | 477153 | 313151 | 55498291 |
Abdominal pain | 99.95 | 9.93 | 2905 | 477720 | 255900 | 55555542 |
Product monitoring error | 98.20 | 9.93 | 134 | 480491 | 3325 | 55808117 |
Orthostatic intolerance | 95.08 | 9.93 | 77 | 480548 | 1012 | 55810430 |
Haematemesis | 94.86 | 9.93 | 491 | 480134 | 28267 | 55783175 |
Tubulointerstitial nephritis | 94.18 | 9.93 | 335 | 480290 | 16330 | 55795112 |
Injection site pruritus | 89.46 | 9.93 | 137 | 480488 | 41794 | 55769648 |
Hepatic function abnormal | 83.70 | 9.93 | 103 | 480522 | 34455 | 55776987 |
Therapeutic product effect incomplete | 81.34 | 9.93 | 550 | 480075 | 105481 | 55705961 |
Subacute cutaneous lupus erythematosus | 80.73 | 9.93 | 100 | 480525 | 2249 | 55809193 |
Hypokalaemia | 80.44 | 9.93 | 1192 | 479433 | 93245 | 55718197 |
Melaena | 77.27 | 9.93 | 459 | 480166 | 27831 | 55783611 |
Sedation complication | 76.81 | 9.93 | 6 | 480619 | 11666 | 55799776 |
Foetal exposure during pregnancy | 76.58 | 9.93 | 106 | 480519 | 33717 | 55777725 |
No adverse event | 76.49 | 9.93 | 120 | 480505 | 36254 | 55775188 |
Accidental exposure to product | 76.43 | 9.93 | 59 | 480566 | 24588 | 55786854 |
Overdose | 73.41 | 9.93 | 565 | 480060 | 105265 | 55706177 |
Drug resistance | 73.38 | 9.93 | 42 | 480583 | 20500 | 55790942 |
Premature delivery | 72.82 | 9.93 | 74 | 480551 | 26986 | 55784456 |
Weight increased | 72.54 | 9.93 | 2517 | 478108 | 227186 | 55584256 |
Hypocalcaemia | 72.47 | 9.93 | 457 | 480168 | 28303 | 55783139 |
Cardio-respiratory arrest | 71.26 | 9.93 | 238 | 480387 | 55083 | 55756359 |
Drug intolerance | 70.92 | 9.93 | 1720 | 478905 | 263098 | 55548344 |
Respiratory disorder | 69.15 | 9.93 | 512 | 480113 | 33445 | 55777997 |
Agranulocytosis | 68.69 | 9.93 | 378 | 480247 | 22281 | 55789161 |
Seizure | 68.35 | 9.93 | 710 | 479915 | 124409 | 55687033 |
Pyrexia | 65.23 | 9.93 | 4277 | 476348 | 414496 | 55396946 |
Respiratory arrest | 64.43 | 9.93 | 101 | 480524 | 30524 | 55780918 |
Neuropathy peripheral | 63.34 | 9.93 | 567 | 480058 | 102326 | 55709116 |
Sedation | 63.33 | 9.93 | 126 | 480499 | 34728 | 55776714 |
Suicidal ideation | 62.93 | 9.93 | 266 | 480359 | 57476 | 55753966 |
Liver injury | 62.27 | 9.93 | 588 | 480037 | 41260 | 55770182 |
Infection | 62.24 | 9.93 | 2190 | 478435 | 198016 | 55613426 |
Therapeutic response decreased | 61.30 | 9.93 | 237 | 480388 | 52521 | 55758921 |
Injection site bruising | 61.16 | 9.93 | 150 | 480475 | 38371 | 55773071 |
Disease progression | 61.11 | 9.93 | 588 | 480037 | 104585 | 55706857 |
Alopecia | 59.49 | 9.93 | 1981 | 478644 | 291477 | 55519965 |
Product use in unapproved indication | 59.45 | 9.93 | 845 | 479780 | 139977 | 55671465 |
Gastrointestinal haemorrhage | 59.04 | 9.93 | 944 | 479681 | 75007 | 55736435 |
Gastritis | 56.93 | 9.93 | 498 | 480127 | 34204 | 55777238 |
Depression | 56.75 | 9.93 | 1140 | 479485 | 178977 | 55632465 |
Eosinophilia | 55.64 | 9.93 | 327 | 480298 | 19750 | 55791692 |
Foetal death | 54.89 | 9.93 | 5 | 480620 | 8582 | 55802860 |
Contusion | 52.93 | 9.93 | 1454 | 479171 | 126976 | 55684466 |
Breast cancer | 52.57 | 9.93 | 226 | 480399 | 48607 | 55762835 |
Anaphylactic reaction | 52.54 | 9.93 | 292 | 480333 | 58703 | 55752739 |
Renal failure | 51.64 | 9.93 | 1272 | 479353 | 109228 | 55702214 |
Drug dependence | 51.63 | 9.93 | 70 | 480555 | 22463 | 55788979 |
Helicobacter infection | 51.56 | 9.93 | 896 | 479729 | 72372 | 55739070 |
Coma | 51.12 | 9.93 | 299 | 480326 | 59356 | 55752086 |
Hypoaesthesia | 50.62 | 9.93 | 876 | 479749 | 140615 | 55670827 |
Malaise | 49.99 | 9.93 | 2599 | 478026 | 365261 | 55446181 |
Faecaloma | 49.49 | 9.93 | 158 | 480467 | 7283 | 55804159 |
Gastrooesophageal reflux disease | 48.86 | 9.93 | 990 | 479635 | 82267 | 55729175 |
Pallor | 48.53 | 9.93 | 363 | 480262 | 23786 | 55787656 |
Suicide attempt | 48.44 | 9.93 | 292 | 480333 | 57544 | 55753898 |
Leukopenia | 47.95 | 9.93 | 862 | 479763 | 70078 | 55741364 |
Intentional self-injury | 47.45 | 9.93 | 88 | 480537 | 24904 | 55786538 |
Caesarean section | 46.82 | 9.93 | 41 | 480584 | 16050 | 55795392 |
White blood cell count decreased | 46.38 | 9.93 | 776 | 479849 | 125214 | 55686228 |
Hypertensive nephropathy | 45.03 | 9.93 | 37 | 480588 | 497 | 55810945 |
Rebound acid hypersecretion | 44.96 | 9.93 | 30 | 480595 | 286 | 55811156 |
Blood loss anaemia | 44.52 | 9.93 | 164 | 480461 | 8133 | 55803309 |
Feeling abnormal | 44.07 | 9.93 | 839 | 479786 | 132763 | 55678679 |
Electrolyte imbalance | 43.86 | 9.93 | 284 | 480341 | 17749 | 55793693 |
Myelosuppression | 43.35 | 9.93 | 51 | 480574 | 17404 | 55794038 |
Intentional product misuse | 43.15 | 9.93 | 260 | 480365 | 51244 | 55760198 |
Vomiting | 42.60 | 9.93 | 4867 | 475758 | 493361 | 55318081 |
Irritability | 42.57 | 9.93 | 121 | 480504 | 29467 | 55781975 |
Drug reaction with eosinophilia and systemic symptoms | 42.23 | 9.93 | 420 | 480205 | 29884 | 55781558 |
Psoriasis | 42.06 | 9.93 | 548 | 480077 | 92144 | 55719298 |
Injection site warmth | 41.79 | 9.93 | 36 | 480589 | 14207 | 55797235 |
Breast cancer female | 41.59 | 9.93 | 27 | 480598 | 12311 | 55799131 |
Lung diffusion test abnormal | 41.56 | 9.93 | 27 | 480598 | 245 | 55811197 |
Stillbirth | 41.44 | 9.93 | 3 | 480622 | 6211 | 55805231 |
Duodenal ulcer perforation | 41.22 | 9.93 | 816 | 479809 | 67526 | 55743916 |
Flushing | 41.10 | 9.93 | 391 | 480234 | 69709 | 55741733 |
Dystonia | 40.77 | 9.93 | 28 | 480597 | 12393 | 55799049 |
Adverse drug reaction | 40.03 | 9.93 | 359 | 480266 | 64773 | 55746669 |
Therapeutic drug monitoring analysis not performed | 39.82 | 9.93 | 46 | 480579 | 959 | 55810483 |
Pneumonia viral | 39.68 | 9.93 | 143 | 480482 | 7015 | 55804427 |
Genital haemorrhage | 38.92 | 9.93 | 6 | 480619 | 6856 | 55804586 |
Nasopharyngitis | 38.60 | 9.93 | 2280 | 478345 | 218679 | 55592763 |
Device difficult to use | 38.44 | 9.93 | 22 | 480603 | 10739 | 55800703 |
Product quality issue | 37.23 | 9.93 | 142 | 480483 | 31594 | 55779848 |
Pre-eclampsia | 37.12 | 9.93 | 13 | 480612 | 8473 | 55802969 |
Balance disorder | 37.11 | 9.93 | 446 | 480179 | 76074 | 55735368 |
Neutropenic sepsis | 37.04 | 9.93 | 45 | 480580 | 15140 | 55796302 |
Premature baby | 37.02 | 9.93 | 67 | 480558 | 19138 | 55792304 |
Platelet count decreased | 36.97 | 9.93 | 662 | 479963 | 105721 | 55705721 |
Cellulitis | 36.67 | 9.93 | 436 | 480189 | 74513 | 55736929 |
Injection site haemorrhage | 36.39 | 9.93 | 85 | 480540 | 22116 | 55789326 |
Musculoskeletal stiffness | 35.73 | 9.93 | 1036 | 479589 | 154971 | 55656471 |
Cholestasis | 35.58 | 9.93 | 369 | 480256 | 26544 | 55784898 |
Clostridium test positive | 35.58 | 9.93 | 71 | 480554 | 2434 | 55809008 |
Neutrophil count decreased | 35.47 | 9.93 | 264 | 480361 | 49558 | 55761884 |
Joint injury | 35.39 | 9.93 | 107 | 480518 | 25547 | 55785895 |
Angina pectoris | 35.31 | 9.93 | 380 | 480245 | 27596 | 55783846 |
Polyneuropathy | 35.16 | 9.93 | 211 | 480414 | 12839 | 55798603 |
Injection site rash | 34.66 | 9.93 | 57 | 480568 | 16901 | 55794541 |
Device issue | 34.44 | 9.93 | 81 | 480544 | 21025 | 55790417 |
Hyperkinesia | 34.28 | 9.93 | 55 | 480570 | 1584 | 55809858 |
Cardiac arrest | 33.62 | 9.93 | 526 | 480099 | 85788 | 55725654 |
Dyspepsia | 33.53 | 9.93 | 942 | 479683 | 82529 | 55728913 |
Joint stiffness | 33.39 | 9.93 | 172 | 480453 | 35253 | 55776189 |
Loss of personal independence in daily activities | 33.36 | 9.93 | 491 | 480134 | 80878 | 55730564 |
Mycotic allergy | 33.05 | 9.93 | 38 | 480587 | 788 | 55810654 |
Haematoma | 32.47 | 9.93 | 417 | 480208 | 31602 | 55779840 |
Hypoparathyroidism secondary | 32.35 | 9.93 | 13 | 480612 | 35 | 55811407 |
Sleep disorder | 32.23 | 9.93 | 781 | 479844 | 66882 | 55744560 |
Haemoglobin decreased | 32.20 | 9.93 | 1427 | 479198 | 132710 | 55678732 |
Drug ineffective for unapproved indication | 32.09 | 9.93 | 112 | 480513 | 25581 | 55785861 |
Cachexia | 32.02 | 9.93 | 104 | 480521 | 4838 | 55806604 |
Eructation | 31.90 | 9.93 | 139 | 480486 | 7449 | 55803993 |
Musculoskeletal disorder | 31.63 | 9.93 | 73 | 480552 | 19074 | 55792368 |
Product storage error | 31.35 | 9.93 | 40 | 480585 | 13173 | 55798269 |
Bursitis | 31.34 | 9.93 | 367 | 480258 | 27215 | 55784227 |
Gestational diabetes | 31.00 | 9.93 | 15 | 480610 | 8049 | 55803393 |
Gastroenteritis clostridial | 30.59 | 9.93 | 31 | 480594 | 554 | 55810888 |
Somnolence | 30.55 | 9.93 | 1114 | 479511 | 162299 | 55649143 |
Breath sounds abnormal | 30.55 | 9.93 | 155 | 480470 | 8852 | 55802590 |
Anxiety | 30.49 | 9.93 | 1343 | 479282 | 191829 | 55619613 |
Device use error | 30.43 | 9.93 | 5 | 480620 | 5451 | 55805991 |
Soft tissue disorder | 30.39 | 9.93 | 93 | 480532 | 4189 | 55807253 |
Restlessness | 30.32 | 9.93 | 354 | 480271 | 26232 | 55785210 |
Device dislocation | 29.98 | 9.93 | 96 | 480529 | 22510 | 55788932 |
Vision blurred | 29.82 | 9.93 | 513 | 480112 | 82430 | 55729012 |
Product used for unknown indication | 29.70 | 9.93 | 35 | 480590 | 746 | 55810696 |
Painful respiration | 29.60 | 9.93 | 66 | 480559 | 2448 | 55808994 |
Enthesopathy | 29.50 | 9.93 | 16 | 480609 | 8047 | 55803395 |
Blood pressure systolic increased | 29.30 | 9.93 | 501 | 480124 | 40335 | 55771107 |
Abnormal behaviour | 29.09 | 9.93 | 83 | 480542 | 20189 | 55791253 |
Dehydration | 28.89 | 9.93 | 1645 | 478980 | 157180 | 55654262 |
Depressed level of consciousness | 28.88 | 9.93 | 325 | 480300 | 56108 | 55755334 |
Drug withdrawal syndrome | 28.86 | 9.93 | 118 | 480507 | 25739 | 55785703 |
Diabetic nephropathy | 28.84 | 9.93 | 46 | 480579 | 1318 | 55810124 |
Pain in jaw | 28.57 | 9.93 | 212 | 480413 | 39824 | 55771618 |
Therapy non-responder | 28.47 | 9.93 | 361 | 480264 | 60994 | 55750448 |
Uterine perforation | 28.40 | 9.93 | 10 | 480615 | 6495 | 55804947 |
Red blood cell sedimentation rate increased | 28.05 | 9.93 | 190 | 480435 | 36433 | 55775009 |
Injection site urticaria | 28.01 | 9.93 | 41 | 480584 | 12742 | 55798700 |
Drug eruption | 27.87 | 9.93 | 119 | 480506 | 25644 | 55785798 |
Abortion induced | 27.55 | 9.93 | 25 | 480600 | 9620 | 55801822 |
Dyspnoea exertional | 27.49 | 9.93 | 636 | 479989 | 54053 | 55757389 |
Hypochromic anaemia | 27.20 | 9.93 | 53 | 480572 | 1785 | 55809657 |
Renal impairment | 27.08 | 9.93 | 891 | 479734 | 79822 | 55731620 |
Abdominal pain lower | 27.01 | 9.93 | 309 | 480316 | 22783 | 55788659 |
Oesophagitis | 26.96 | 9.93 | 209 | 480416 | 13848 | 55797594 |
Mydriasis | 26.80 | 9.93 | 33 | 480592 | 11038 | 55800404 |
Fear of injection | 26.80 | 9.93 | 11 | 480614 | 6504 | 55804938 |
Treatment noncompliance | 26.64 | 9.93 | 166 | 480459 | 32457 | 55778985 |
Trimethylaminuria | 26.60 | 9.93 | 16 | 480609 | 125 | 55811317 |
Hepatitis cholestatic | 26.59 | 9.93 | 117 | 480508 | 6297 | 55805145 |
Temperature regulation disorder | 26.27 | 9.93 | 91 | 480534 | 4377 | 55807065 |
Acute abdomen | 26.16 | 9.93 | 46 | 480579 | 1430 | 55810012 |
Glomerulonephropathy | 26.15 | 9.93 | 14 | 480611 | 85 | 55811357 |
Febrile infection | 25.80 | 9.93 | 44 | 480581 | 1334 | 55810108 |
Substance abuse | 25.57 | 9.93 | 4 | 480621 | 4521 | 55806921 |
Headache | 25.35 | 9.93 | 4292 | 476333 | 554752 | 55256690 |
Premature rupture of membranes | 25.20 | 9.93 | 5 | 480620 | 4760 | 55806682 |
Gastric ulcer | 25.10 | 9.93 | 299 | 480326 | 22264 | 55789178 |
Product use issue | 24.90 | 9.93 | 1316 | 479309 | 184725 | 55626717 |
Blood parathyroid hormone decreased | 24.71 | 9.93 | 21 | 480604 | 8343 | 55803099 |
Hiatus hernia | 24.37 | 9.93 | 266 | 480359 | 19386 | 55792056 |
Heavy menstrual bleeding | 24.28 | 9.93 | 65 | 480560 | 16144 | 55795298 |
Food allergy | 23.98 | 9.93 | 143 | 480482 | 8681 | 55802761 |
Duodenitis | 23.83 | 9.93 | 74 | 480551 | 3360 | 55808082 |
Dysphoria | 23.76 | 9.93 | 6 | 480619 | 4836 | 55806606 |
Poisoning deliberate | 23.75 | 9.93 | 30 | 480595 | 9923 | 55801519 |
Disseminated intravascular coagulation | 23.68 | 9.93 | 76 | 480549 | 17809 | 55793633 |
Nephrogenic anaemia | 23.57 | 9.93 | 51 | 480574 | 1853 | 55809589 |
Clostridium difficile colitis | 23.41 | 9.93 | 254 | 480371 | 18484 | 55792958 |
Hypertensive crisis | 23.31 | 9.93 | 202 | 480423 | 13834 | 55797608 |
Device malfunction | 23.20 | 9.93 | 66 | 480559 | 16070 | 55795372 |
Complication of device insertion | 23.14 | 9.93 | 13 | 480612 | 6411 | 55805031 |
Serotonin syndrome | 23.10 | 9.93 | 132 | 480493 | 26358 | 55785084 |
Granuloma skin | 23.00 | 9.93 | 16 | 480609 | 7035 | 55804407 |
Brain contusion | 22.92 | 9.93 | 26 | 480599 | 531 | 55810911 |
Wheelchair user | 22.86 | 9.93 | 9 | 480616 | 5457 | 55805985 |
Gastrointestinal toxicity | 22.84 | 9.93 | 12 | 480613 | 6144 | 55805298 |
Joint swelling | 22.70 | 9.93 | 2816 | 477809 | 286984 | 55524458 |
Body temperature decreased | 22.41 | 9.93 | 245 | 480380 | 17863 | 55793579 |
Atrial fibrillation | 22.41 | 9.93 | 1141 | 479484 | 107756 | 55703686 |
Pancreatic steatosis | 22.35 | 9.93 | 34 | 480591 | 934 | 55810508 |
Neuroleptic malignant syndrome | 22.16 | 9.93 | 40 | 480585 | 11438 | 55800004 |
Colitis erosive | 22.13 | 9.93 | 12 | 480613 | 75 | 55811367 |
Gamma-glutamyltransferase increased | 22.10 | 9.93 | 380 | 480245 | 30625 | 55780817 |
Coagulation test abnormal | 22.07 | 9.93 | 29 | 480596 | 693 | 55810749 |
Low birth weight baby | 22.06 | 9.93 | 13 | 480612 | 6245 | 55805197 |
Multiple sclerosis relapse | 22.04 | 9.93 | 261 | 480364 | 44642 | 55766800 |
Urosepsis | 22.01 | 9.93 | 229 | 480396 | 16487 | 55794955 |
Spinal pain | 21.86 | 9.93 | 175 | 480450 | 11709 | 55799733 |
Hyperkalaemia | 21.83 | 9.93 | 579 | 480046 | 50286 | 55761156 |
Device breakage | 21.79 | 9.93 | 33 | 480592 | 10114 | 55801328 |
Normal newborn | 21.77 | 9.93 | 19 | 480606 | 7451 | 55803991 |
Cerebral ischaemia | 21.68 | 9.93 | 107 | 480518 | 6043 | 55805399 |
Pulmonary embolism | 21.34 | 9.93 | 1119 | 479506 | 106005 | 55705437 |
Therapeutic drug monitoring analysis incorrectly performed | 21.30 | 9.93 | 16 | 480609 | 187 | 55811255 |
Wheezing | 21.16 | 9.93 | 812 | 479813 | 74214 | 55737228 |
Panniculitis | 21.14 | 9.93 | 32 | 480593 | 9810 | 55801632 |
Folate deficiency | 21.12 | 9.93 | 53 | 480572 | 2124 | 55809318 |
Oesophageal dilatation | 21.11 | 9.93 | 20 | 480605 | 328 | 55811114 |
Cholecystitis chronic | 21.00 | 9.93 | 149 | 480476 | 9599 | 55801843 |
Haematocrit decreased | 20.96 | 9.93 | 436 | 480189 | 36393 | 55775049 |
Nasal obstruction | 20.91 | 9.93 | 38 | 480587 | 1213 | 55810229 |
Total lung capacity decreased | 20.91 | 9.93 | 42 | 480583 | 1447 | 55809995 |
Skin disorder | 20.90 | 9.93 | 135 | 480490 | 26174 | 55785268 |
Shock | 20.76 | 9.93 | 105 | 480520 | 21623 | 55789819 |
Synovial fluid analysis | 20.74 | 9.93 | 49 | 480576 | 1889 | 55809553 |
Injection site discolouration | 20.52 | 9.93 | 19 | 480606 | 7240 | 55804202 |
Neck pain | 20.45 | 9.93 | 386 | 480239 | 61169 | 55750273 |
Abdominal wall wound | 20.38 | 9.93 | 11 | 480614 | 68 | 55811374 |
Gastritis erosive | 20.35 | 9.93 | 98 | 480527 | 5479 | 55805963 |
Knee arthroplasty | 20.31 | 9.93 | 261 | 480364 | 43998 | 55767444 |
Status epilepticus | 20.28 | 9.93 | 64 | 480561 | 15077 | 55796365 |
Poisoning | 20.25 | 9.93 | 50 | 480575 | 12763 | 55798679 |
Breast cancer stage II | 20.24 | 9.93 | 12 | 480613 | 5746 | 55805696 |
Hepatitis acute | 19.95 | 9.93 | 131 | 480494 | 8226 | 55803216 |
Dysuria | 19.92 | 9.93 | 371 | 480254 | 30358 | 55781084 |
Deafness | 19.87 | 9.93 | 73 | 480552 | 16421 | 55795021 |
Internal haemorrhage | 19.82 | 9.93 | 87 | 480538 | 4677 | 55806765 |
Nephritis allergic | 19.79 | 9.93 | 14 | 480611 | 148 | 55811294 |
Peripheral arterial occlusive disease | 19.74 | 9.93 | 75 | 480550 | 3775 | 55807667 |
Iron deficiency anaemia | 19.73 | 9.93 | 237 | 480388 | 17682 | 55793760 |
Medication error | 19.66 | 9.93 | 487 | 480138 | 41848 | 55769594 |
Urinary tract obstruction | 19.63 | 9.93 | 47 | 480578 | 1828 | 55809614 |
Spontaneous haemorrhage | 19.61 | 9.93 | 18 | 480607 | 283 | 55811159 |
Surgery | 19.55 | 9.93 | 180 | 480445 | 32306 | 55779136 |
Amenorrhoea | 19.51 | 9.93 | 29 | 480596 | 8957 | 55802485 |
Pregnancy | 19.46 | 9.93 | 184 | 480441 | 32849 | 55778593 |
Bacteriuria | 19.31 | 9.93 | 31 | 480594 | 893 | 55810549 |
Adenovirus infection | 19.28 | 9.93 | 3 | 480622 | 3405 | 55808037 |
Chronic gastritis | 19.25 | 9.93 | 57 | 480568 | 2521 | 55808921 |
Basal cell carcinoma | 19.24 | 9.93 | 131 | 480494 | 25090 | 55786352 |
Pancytopenia | 19.17 | 9.93 | 934 | 479691 | 87781 | 55723661 |
Rapid eye movement sleep behaviour disorder | 19.17 | 9.93 | 15 | 480610 | 187 | 55811255 |
Complication associated with device | 19.11 | 9.93 | 67 | 480558 | 15283 | 55796159 |
Hepatotoxicity | 19.01 | 9.93 | 172 | 480453 | 30981 | 55780461 |
Neuropathy vitamin B12 deficiency | 18.86 | 9.93 | 5 | 480620 | 0 | 55811442 |
Haemorrhagic erosive gastritis | 18.81 | 9.93 | 18 | 480607 | 299 | 55811143 |
Blood pressure diastolic abnormal | 18.79 | 9.93 | 166 | 480459 | 11432 | 55800010 |
Tenosynovitis stenosans | 18.77 | 9.93 | 57 | 480568 | 2557 | 55808885 |
Cardiac failure | 18.74 | 9.93 | 869 | 479756 | 81224 | 55730218 |
Flatulence | 18.66 | 9.93 | 373 | 480252 | 30915 | 55780527 |
Pharyngeal dystonia | 18.52 | 9.93 | 6 | 480619 | 6 | 55811436 |
Thrombocytopenia | 18.44 | 9.93 | 1376 | 479249 | 134848 | 55676594 |
Discontinued product administered | 18.36 | 9.93 | 9 | 480616 | 44 | 55811398 |
Blood calcium decreased | 18.36 | 9.93 | 123 | 480502 | 23646 | 55787796 |
Epstein-Barr virus infection | 18.33 | 9.93 | 22 | 480603 | 7441 | 55804001 |
Somatic symptom disorder | 18.27 | 9.93 | 49 | 480576 | 2046 | 55809396 |
Sopor | 18.16 | 9.93 | 265 | 480360 | 20657 | 55790785 |
Multiple sclerosis | 18.08 | 9.93 | 151 | 480474 | 27651 | 55783791 |
Hepatic cyst | 18.06 | 9.93 | 85 | 480540 | 4708 | 55806734 |
Fall | 18.03 | 9.93 | 3389 | 477236 | 354121 | 55457321 |
Rib deformity | 17.98 | 9.93 | 15 | 480610 | 206 | 55811236 |
Injection site mass | 17.90 | 9.93 | 78 | 480547 | 16715 | 55794727 |
Complication of device removal | 17.90 | 9.93 | 8 | 480617 | 4496 | 55806946 |
Gastric haemorrhage | 17.86 | 9.93 | 99 | 480526 | 5851 | 55805591 |
Jaundice | 17.85 | 9.93 | 330 | 480295 | 26964 | 55784478 |
Throat clearing | 17.83 | 9.93 | 40 | 480585 | 1490 | 55809952 |
Cardiorenal syndrome | 17.81 | 9.93 | 28 | 480597 | 792 | 55810650 |
Pathogen resistance | 17.81 | 9.93 | 15 | 480610 | 5985 | 55805457 |
Troponin abnormal | 17.77 | 9.93 | 8 | 480617 | 31 | 55811411 |
Akathisia | 17.76 | 9.93 | 29 | 480596 | 8623 | 55802819 |
Condition aggravated | 17.56 | 9.93 | 2630 | 477995 | 342268 | 55469174 |
Abnormal faeces | 17.56 | 9.93 | 84 | 480541 | 4684 | 55806758 |
Obstructive airways disorder | 17.49 | 9.93 | 225 | 480400 | 17057 | 55794385 |
Drug use disorder | 17.47 | 9.93 | 9 | 480616 | 4660 | 55806782 |
Solar urticaria | 17.45 | 9.93 | 9 | 480616 | 50 | 55811392 |
Patent ductus arteriosus | 17.37 | 9.93 | 6 | 480619 | 3945 | 55807497 |
Maternal drugs affecting foetus | 17.37 | 9.93 | 11 | 480614 | 5082 | 55806360 |
Paresis | 17.34 | 9.93 | 51 | 480574 | 2247 | 55809195 |
Tetany | 17.27 | 9.93 | 42 | 480583 | 1650 | 55809792 |
Lethargy | 17.27 | 9.93 | 322 | 480303 | 51119 | 55760323 |
Acute graft versus host disease | 17.25 | 9.93 | 7 | 480618 | 4168 | 55807274 |
Exposure to toxic agent | 17.22 | 9.93 | 5 | 480620 | 3673 | 55807769 |
Occupational asthma | 17.03 | 9.93 | 12 | 480613 | 126 | 55811316 |
Therapy partial responder | 17.02 | 9.93 | 25 | 480600 | 7760 | 55803682 |
Macular degeneration | 17.01 | 9.93 | 241 | 480384 | 18667 | 55792775 |
Urinary tract infection enterococcal | 16.99 | 9.93 | 55 | 480570 | 2554 | 55808888 |
Pseudarthrosis | 16.95 | 9.93 | 20 | 480605 | 427 | 55811015 |
Mobility decreased | 16.91 | 9.93 | 682 | 479943 | 98309 | 55713133 |
Systemic lupus erythematosus | 16.84 | 9.93 | 1316 | 479309 | 178762 | 55632680 |
Hepatitis B | 16.83 | 9.93 | 5 | 480620 | 3619 | 55807823 |
Device deployment issue | 16.83 | 9.93 | 5 | 480620 | 3619 | 55807823 |
Cystostomy | 16.76 | 9.93 | 9 | 480616 | 55 | 55811387 |
Tachyarrhythmia | 16.75 | 9.93 | 76 | 480549 | 4145 | 55807297 |
Tuberculosis | 16.69 | 9.93 | 44 | 480581 | 10985 | 55800457 |
Reactive gastropathy | 16.60 | 9.93 | 19 | 480606 | 392 | 55811050 |
Renal cyst | 16.54 | 9.93 | 136 | 480489 | 9173 | 55802269 |
Creatinine renal clearance decreased | 16.53 | 9.93 | 66 | 480559 | 14493 | 55796949 |
Sensory level abnormal | 16.50 | 9.93 | 12 | 480613 | 133 | 55811309 |
Musculoskeletal pain | 16.42 | 9.93 | 849 | 479776 | 80303 | 55731139 |
Underdose | 16.38 | 9.93 | 127 | 480498 | 23630 | 55787812 |
Agitation | 16.35 | 9.93 | 359 | 480266 | 55677 | 55755765 |
Product complaint | 16.26 | 9.93 | 49 | 480576 | 11711 | 55799731 |
Arterial occlusive disease | 16.23 | 9.93 | 90 | 480535 | 5320 | 55806122 |
Pulmonary tuberculosis | 16.20 | 9.93 | 9 | 480616 | 4467 | 55806975 |
Haemarthrosis | 16.19 | 9.93 | 60 | 480565 | 2984 | 55808458 |
Therapeutic product effect decreased | 16.16 | 9.93 | 1668 | 478957 | 167784 | 55643658 |
Vaginal haemorrhage | 15.99 | 9.93 | 141 | 480484 | 25532 | 55785910 |
Prerenal failure | 15.97 | 9.93 | 39 | 480586 | 1536 | 55809906 |
Arterial stenosis | 15.88 | 9.93 | 22 | 480603 | 554 | 55810888 |
Demyelination | 15.87 | 9.93 | 18 | 480607 | 6244 | 55805198 |
Hip arthroplasty | 15.84 | 9.93 | 233 | 480392 | 38390 | 55773052 |
Hepatocellular injury | 15.78 | 9.93 | 316 | 480309 | 26198 | 55785244 |
Bicytopenia | 15.77 | 9.93 | 47 | 480578 | 2086 | 55809356 |
Mixed liver injury | 15.64 | 9.93 | 71 | 480554 | 3873 | 55807569 |
Subileus | 15.63 | 9.93 | 58 | 480567 | 2886 | 55808556 |
Salpingo-oophorectomy unilateral | 15.55 | 9.93 | 24 | 480601 | 668 | 55810774 |
Colorectal cancer | 15.44 | 9.93 | 5 | 480620 | 3424 | 55808018 |
Cytomegalovirus infection | 15.33 | 9.93 | 99 | 480526 | 19197 | 55792245 |
Faeces hard | 15.33 | 9.93 | 42 | 480583 | 1776 | 55809666 |
Megacolon | 15.31 | 9.93 | 41 | 480584 | 1710 | 55809732 |
Incorrect dose administered | 15.23 | 9.93 | 337 | 480288 | 52210 | 55759232 |
Tongue disorder | 15.22 | 9.93 | 40 | 480585 | 9996 | 55801446 |
Post procedural pulmonary embolism | 15.21 | 9.93 | 15 | 480610 | 259 | 55811183 |
Carcinoid tumour of the stomach | 15.18 | 9.93 | 12 | 480613 | 152 | 55811290 |
Fracture | 15.16 | 9.93 | 227 | 480398 | 17791 | 55793651 |
Aortic valve stenosis | 15.07 | 9.93 | 60 | 480565 | 3087 | 55808355 |
Prothrombin time shortened | 14.99 | 9.93 | 41 | 480584 | 1732 | 55809710 |
Neutrophil function disorder | 14.97 | 9.93 | 6 | 480619 | 16 | 55811426 |
Intermenstrual bleeding | 14.95 | 9.93 | 23 | 480602 | 7004 | 55804438 |
Red blood cell count decreased | 14.91 | 9.93 | 414 | 480211 | 36203 | 55775239 |
Biliary dyskinesia | 14.89 | 9.93 | 52 | 480573 | 2511 | 55808931 |
Live birth | 14.87 | 9.93 | 102 | 480523 | 19503 | 55791939 |
Hypomania | 14.86 | 9.93 | 12 | 480613 | 4890 | 55806552 |
Diverticulum intestinal | 14.80 | 9.93 | 100 | 480525 | 6340 | 55805102 |
Lipoedema | 14.76 | 9.93 | 15 | 480610 | 269 | 55811173 |
Drug-induced liver injury | 14.70 | 9.93 | 392 | 480233 | 34070 | 55777372 |
Suspected suicide | 14.65 | 9.93 | 15 | 480610 | 5451 | 55805991 |
Polycystic ovaries | 14.63 | 9.93 | 5 | 480620 | 3309 | 55808133 |
Colitis ulcerative | 14.62 | 9.93 | 291 | 480334 | 24100 | 55787342 |
Osteomyelitis | 14.60 | 9.93 | 135 | 480490 | 24211 | 55787231 |
Smear cervix abnormal | 14.54 | 9.93 | 3 | 480622 | 2778 | 55808664 |
Stoma site discharge | 14.52 | 9.93 | 35 | 480590 | 1367 | 55810075 |
Clostridium difficile infection | 14.51 | 9.93 | 319 | 480306 | 26879 | 55784563 |
Hepatic vein dilatation | 14.47 | 9.93 | 6 | 480619 | 18 | 55811424 |
Feeling jittery | 14.46 | 9.93 | 162 | 480463 | 11884 | 55799558 |
Neutropenia | 14.45 | 9.93 | 1158 | 479467 | 157009 | 55654433 |
Pseudomembranous colitis | 14.43 | 9.93 | 56 | 480569 | 2847 | 55808595 |
Gastrointestinal inflammation | 14.39 | 9.93 | 82 | 480543 | 4896 | 55806546 |
Lymphoproliferative disorder | 14.39 | 9.93 | 4 | 480621 | 3024 | 55808418 |
Multiple-drug resistance | 14.37 | 9.93 | 8 | 480617 | 3966 | 55807476 |
Dysphagia | 14.36 | 9.93 | 846 | 479779 | 81101 | 55730341 |
Respiratory depression | 14.35 | 9.93 | 56 | 480569 | 12379 | 55799063 |
Tooth disorder | 14.35 | 9.93 | 144 | 480481 | 25409 | 55786033 |
Unevaluable event | 14.35 | 9.93 | 304 | 480321 | 47383 | 55764059 |
Epigastric discomfort | 14.35 | 9.93 | 97 | 480528 | 6151 | 55805291 |
Schizophrenia | 14.33 | 9.93 | 44 | 480581 | 10455 | 55800987 |
Erysipelas | 14.25 | 9.93 | 108 | 480517 | 7105 | 55804337 |
Thrombosis prophylaxis | 14.23 | 9.93 | 6 | 480619 | 19 | 55811423 |
Cholecystitis | 14.22 | 9.93 | 187 | 480438 | 14248 | 55797194 |
Pneumonia aspiration | 14.19 | 9.93 | 193 | 480432 | 32218 | 55779224 |
COVID-19 | 14.16 | 9.93 | 511 | 480114 | 74547 | 55736895 |
Injection site induration | 14.11 | 9.93 | 33 | 480592 | 8582 | 55802860 |
Toothache | 14.07 | 9.93 | 92 | 480533 | 17788 | 55793654 |
Eosinophils urine present | 14.00 | 9.93 | 6 | 480619 | 20 | 55811422 |
Oedema peripheral | 13.90 | 9.93 | 1668 | 478957 | 169586 | 55641856 |
Hypochloraemia | 13.89 | 9.93 | 39 | 480586 | 1673 | 55809769 |
Haematotoxicity | 13.82 | 9.93 | 32 | 480593 | 8351 | 55803091 |
Strangury | 13.79 | 9.93 | 5 | 480620 | 9 | 55811433 |
Peripheral venous disease | 13.71 | 9.93 | 139 | 480486 | 9940 | 55801502 |
Vocal cord dysfunction | 13.70 | 9.93 | 17 | 480608 | 383 | 55811059 |
Hypersensitivity | 13.69 | 9.93 | 2438 | 478187 | 253970 | 55557472 |
Upper gastrointestinal haemorrhage | 13.63 | 9.93 | 213 | 480412 | 16841 | 55794601 |
Glomerular filtration rate decreased | 13.54 | 9.93 | 163 | 480462 | 12166 | 55799276 |
Intraocular pressure increased | 13.53 | 9.93 | 18 | 480607 | 5823 | 55805619 |
Laboratory test abnormal | 13.52 | 9.93 | 140 | 480485 | 24555 | 55786887 |
Abnormal dreams | 13.49 | 9.93 | 40 | 480585 | 9609 | 55801833 |
Gastrointestinal complication associated with device | 13.45 | 9.93 | 5 | 480620 | 10 | 55811432 |
Infusion site pain | 13.44 | 9.93 | 66 | 480559 | 13696 | 55797746 |
Nephropathy | 13.43 | 9.93 | 88 | 480537 | 5521 | 55805921 |
Skin necrosis | 13.43 | 9.93 | 57 | 480568 | 12304 | 55799138 |
Drug tolerance | 13.35 | 9.93 | 19 | 480606 | 5975 | 55805467 |
Pemphigus | 13.31 | 9.93 | 1158 | 479467 | 156054 | 55655388 |
Pharyngitis | 13.30 | 9.93 | 98 | 480527 | 18440 | 55793002 |
Monoparesis | 13.17 | 9.93 | 36 | 480589 | 1520 | 55809922 |
Product administered to patient of inappropriate age | 13.10 | 9.93 | 4 | 480621 | 2844 | 55808598 |
Neurotoxicity | 13.09 | 9.93 | 80 | 480545 | 15715 | 55795727 |
Abdominal discomfort | 13.03 | 9.93 | 2124 | 478501 | 275150 | 55536292 |
Presyncope | 13.01 | 9.93 | 298 | 480327 | 25284 | 55786158 |
Clostridium colitis | 12.97 | 9.93 | 39 | 480586 | 1740 | 55809702 |
Ischaemic stroke | 12.95 | 9.93 | 209 | 480416 | 16633 | 55794809 |
Facet joint syndrome | 12.95 | 9.93 | 100 | 480525 | 6617 | 55804825 |
Hyperplastic cholecystopathy | 12.89 | 9.93 | 9 | 480616 | 93 | 55811349 |
Foot operation | 12.87 | 9.93 | 21 | 480604 | 6246 | 55805196 |
Incorrect dosage administered | 12.81 | 9.93 | 39 | 480586 | 1752 | 55809690 |
Poor venous access | 12.79 | 9.93 | 161 | 480464 | 12145 | 55799297 |
Mood swings | 12.77 | 9.93 | 87 | 480538 | 16660 | 55794782 |
Psychotic disorder | 12.72 | 9.93 | 134 | 480491 | 23424 | 55788018 |
Injection site irritation | 12.67 | 9.93 | 12 | 480613 | 4524 | 55806918 |
Foot deformity | 12.67 | 9.93 | 136 | 480489 | 23689 | 55787753 |
Adverse event | 12.60 | 9.93 | 368 | 480257 | 55008 | 55756434 |
Iron deficiency | 12.55 | 9.93 | 94 | 480531 | 6162 | 55805280 |
Alanine aminotransferase abnormal | 12.55 | 9.93 | 11 | 480614 | 4304 | 55807138 |
Stress | 12.53 | 9.93 | 395 | 480230 | 58515 | 55752927 |
Type I hypersensitivity | 12.48 | 9.93 | 48 | 480577 | 2430 | 55809012 |
Atelectasis | 12.47 | 9.93 | 233 | 480392 | 19075 | 55792367 |
Hypergastrinaemia | 12.43 | 9.93 | 9 | 480616 | 99 | 55811343 |
Pancreatitis | 12.26 | 9.93 | 486 | 480139 | 44594 | 55766848 |
Inappropriate antidiuretic hormone secretion | 12.24 | 9.93 | 175 | 480450 | 13581 | 55797861 |
Myocardial infarction | 12.21 | 9.93 | 658 | 479967 | 92212 | 55719230 |
Retroperitoneal haematoma | 12.21 | 9.93 | 51 | 480574 | 2682 | 55808760 |
Arterial haemorrhage | 12.20 | 9.93 | 36 | 480589 | 1589 | 55809853 |
Premature labour | 12.18 | 9.93 | 56 | 480569 | 11826 | 55799616 |
Rhabdomyolysis | 12.17 | 9.93 | 443 | 480182 | 40215 | 55771227 |
Productive cough | 12.14 | 9.93 | 592 | 480033 | 55640 | 55755802 |
Renal haemangioma | 12.14 | 9.93 | 6 | 480619 | 30 | 55811412 |
Graft versus host disease in skin | 12.10 | 9.93 | 4 | 480621 | 2703 | 55808739 |
Non-economic loss | 12.06 | 9.93 | 5 | 480620 | 15 | 55811427 |
Nightmare | 12.05 | 9.93 | 89 | 480536 | 16737 | 55794705 |
Orthostatic hypotension | 12.03 | 9.93 | 205 | 480420 | 32994 | 55778448 |
Loss of consciousness | 12.02 | 9.93 | 788 | 479837 | 108561 | 55702881 |
Shock haemorrhagic | 12.01 | 9.93 | 124 | 480501 | 8909 | 55802533 |
Sexual dysfunction | 12.00 | 9.93 | 7 | 480618 | 3381 | 55808061 |
Diarrhoea | 11.99 | 9.93 | 5815 | 474810 | 632692 | 55178750 |
Acute generalised exanthematous pustulosis | 11.97 | 9.93 | 133 | 480492 | 9736 | 55801706 |
Waist circumference increased | 11.96 | 9.93 | 23 | 480602 | 767 | 55810675 |
Skin test positive | 11.94 | 9.93 | 21 | 480604 | 653 | 55810789 |
Blood iron abnormal | 11.92 | 9.93 | 7 | 480618 | 3370 | 55808072 |
Swelling face | 11.92 | 9.93 | 376 | 480249 | 55693 | 55755749 |
Pulmonary renal syndrome | 11.91 | 9.93 | 16 | 480609 | 391 | 55811051 |
Flank pain | 11.87 | 9.93 | 180 | 480445 | 14145 | 55797297 |
Bradycardia | 11.84 | 9.93 | 697 | 479928 | 66807 | 55744635 |
Spigelian hernia | 11.83 | 9.93 | 6 | 480619 | 32 | 55811410 |
Neurosensory hypoacusis | 11.82 | 9.93 | 12 | 480613 | 215 | 55811227 |
Syncope | 11.77 | 9.93 | 1075 | 479550 | 107124 | 55704318 |
Metabolic surgery | 11.77 | 9.93 | 29 | 480596 | 1149 | 55810293 |
Femoral hernia incarcerated | 11.74 | 9.93 | 23 | 480602 | 778 | 55810664 |
White blood cell count abnormal | 11.73 | 9.93 | 20 | 480605 | 5847 | 55805595 |
Lip dry | 11.69 | 9.93 | 131 | 480494 | 9609 | 55801833 |
Tachypnoea | 11.69 | 9.93 | 191 | 480434 | 15239 | 55796203 |
Cytomegalovirus viraemia | 11.63 | 9.93 | 16 | 480609 | 5104 | 55806338 |
Cushingoid | 11.61 | 9.93 | 105 | 480520 | 7279 | 55804163 |
Renal atrophy | 11.57 | 9.93 | 32 | 480593 | 1361 | 55810081 |
Natural killer cell count decreased | 11.54 | 9.93 | 6 | 480619 | 34 | 55811408 |
Rectal haemorrhage | 11.50 | 9.93 | 448 | 480177 | 41019 | 55770423 |
Glomerulonephritis chronic | 11.49 | 9.93 | 10 | 480615 | 146 | 55811296 |
Coeliac disease | 11.49 | 9.93 | 137 | 480488 | 10202 | 55801240 |
Carotid arteriosclerosis | 11.49 | 9.93 | 26 | 480599 | 974 | 55810468 |
Tardive dyskinesia | 11.44 | 9.93 | 33 | 480592 | 7998 | 55803444 |
Administration site discomfort | 11.43 | 9.93 | 8 | 480617 | 83 | 55811359 |
Gastroenteritis salmonella | 11.41 | 9.93 | 20 | 480605 | 620 | 55810822 |
Enterochromaffin cell hyperplasia | 11.40 | 9.93 | 7 | 480618 | 57 | 55811385 |
Hyperchlorhydria | 11.39 | 9.93 | 35 | 480590 | 1580 | 55809862 |
Lipase increased | 11.35 | 9.93 | 122 | 480503 | 8857 | 55802585 |
Rheumatoid factor positive | 11.32 | 9.93 | 478 | 480147 | 68582 | 55742860 |
Low density lipoprotein | 11.32 | 9.93 | 3 | 480622 | 0 | 55811442 |
Adenocarcinoma of appendix | 11.32 | 9.93 | 3 | 480622 | 0 | 55811442 |
Vascular access site complication | 11.32 | 9.93 | 3 | 480622 | 0 | 55811442 |
Automatism epileptic | 11.32 | 9.93 | 3 | 480622 | 0 | 55811442 |
Blood pressure ambulatory abnormal | 11.32 | 9.93 | 3 | 480622 | 0 | 55811442 |
Speech rehabilitation | 11.32 | 9.93 | 3 | 480622 | 0 | 55811442 |
Anaesthesia oral | 11.32 | 9.93 | 3 | 480622 | 0 | 55811442 |
Faeces discoloured | 11.29 | 9.93 | 206 | 480419 | 16790 | 55794652 |
Cerebellar ataxia | 11.26 | 9.93 | 24 | 480601 | 863 | 55810579 |
Dissociation | 11.24 | 9.93 | 4 | 480621 | 2581 | 55808861 |
Duodenal polyp | 11.19 | 9.93 | 9 | 480616 | 117 | 55811325 |
Deep vein thrombosis | 11.17 | 9.93 | 782 | 479843 | 76195 | 55735247 |
Bone lesion | 11.12 | 9.93 | 82 | 480543 | 5348 | 55806094 |
Interstitial lung disease | 11.11 | 9.93 | 387 | 480238 | 56676 | 55754766 |
Cholangitis acute | 11.10 | 9.93 | 17 | 480608 | 470 | 55810972 |
Blood pressure diastolic decreased | 11.07 | 9.93 | 229 | 480396 | 19094 | 55792348 |
Blood pressure systolic abnormal | 11.07 | 9.93 | 130 | 480495 | 9647 | 55801795 |
Sacroiliitis | 11.06 | 9.93 | 50 | 480575 | 2722 | 55808720 |
Carcinoid tumour | 11.06 | 9.93 | 15 | 480610 | 370 | 55811072 |
Hyperprolactinaemia | 11.05 | 9.93 | 9 | 480616 | 3652 | 55807790 |
Nephritis | 11.04 | 9.93 | 44 | 480581 | 2265 | 55809177 |
Vaccination site reaction | 11.01 | 9.93 | 9 | 480616 | 120 | 55811322 |
Heart rate | 10.91 | 9.93 | 7 | 480618 | 62 | 55811380 |
Gait deviation | 10.91 | 9.93 | 7 | 480618 | 62 | 55811380 |
Mucormycosis | 10.91 | 9.93 | 5 | 480620 | 2769 | 55808673 |
Rapid correction of hyponatraemia | 10.89 | 9.93 | 9 | 480616 | 122 | 55811320 |
Paralysis | 10.86 | 9.93 | 40 | 480585 | 8992 | 55802450 |
Alkalosis | 10.83 | 9.93 | 14 | 480611 | 329 | 55811113 |
Lymphatic fistula | 10.83 | 9.93 | 22 | 480603 | 764 | 55810678 |
Bacterial test | 10.80 | 9.93 | 28 | 480597 | 1145 | 55810297 |
Paradoxical drug reaction | 10.79 | 9.93 | 10 | 480615 | 3810 | 55807632 |
Myeloblast percentage decreased | 10.63 | 9.93 | 6 | 480619 | 41 | 55811401 |
Gastrointestinal vascular malformation haemorrhagic | 10.62 | 9.93 | 11 | 480614 | 202 | 55811240 |
Wound infection fungal | 10.59 | 9.93 | 9 | 480616 | 127 | 55811315 |
Emphysema | 10.57 | 9.93 | 131 | 480494 | 9845 | 55801597 |
Hepatic steatosis | 10.56 | 9.93 | 296 | 480329 | 25918 | 55785524 |
Pain in extremity | 10.56 | 9.93 | 2312 | 478313 | 295119 | 55516323 |
Total lung capacity abnormal | 10.55 | 9.93 | 7 | 480618 | 66 | 55811376 |
Petit mal epilepsy | 10.55 | 9.93 | 9 | 480616 | 3569 | 55807873 |
Extrapyramidal disorder | 10.54 | 9.93 | 62 | 480563 | 12294 | 55799148 |
Hospitalisation | 10.50 | 9.93 | 528 | 480097 | 74472 | 55736970 |
Vitamin B12 decreased | 10.49 | 9.93 | 53 | 480572 | 3022 | 55808420 |
Dermatitis atopic | 10.48 | 9.93 | 36 | 480589 | 8263 | 55803179 |
Gastritis fungal | 10.47 | 9.93 | 8 | 480617 | 96 | 55811346 |
Dermatitis acneiform | 10.46 | 9.93 | 13 | 480612 | 4331 | 55807111 |
Stenosis | 10.45 | 9.93 | 30 | 480595 | 1304 | 55810138 |
Hepatic enzyme increased | 10.41 | 9.93 | 1641 | 478984 | 169743 | 55641699 |
Gastrointestinal wall thickening | 10.41 | 9.93 | 28 | 480597 | 1171 | 55810271 |
Squamous cell carcinoma of the oral cavity | 10.41 | 9.93 | 13 | 480612 | 295 | 55811147 |
Incorrect product administration duration | 10.38 | 9.93 | 49 | 480576 | 10277 | 55801165 |
N-terminal prohormone brain natriuretic peptide increased | 10.38 | 9.93 | 37 | 480588 | 1805 | 55809637 |
Pneumocystis jirovecii pneumonia | 10.33 | 9.93 | 85 | 480540 | 15616 | 55795826 |
Crepitations | 10.32 | 9.93 | 98 | 480527 | 6886 | 55804556 |
Dysentery | 10.32 | 9.93 | 22 | 480603 | 791 | 55810651 |
Anuria | 10.22 | 9.93 | 149 | 480476 | 11611 | 55799831 |
Uterine cancer | 10.17 | 9.93 | 14 | 480611 | 4465 | 55806977 |
Wound treatment | 10.17 | 9.93 | 10 | 480615 | 172 | 55811270 |
Ear infection | 10.16 | 9.93 | 197 | 480428 | 31098 | 55780344 |
Blood glucose increased | 10.15 | 9.93 | 531 | 480094 | 74620 | 55736822 |
Labelled drug-food interaction medication error | 10.15 | 9.93 | 9 | 480616 | 135 | 55811307 |
Fear | 10.14 | 9.93 | 80 | 480545 | 14828 | 55796614 |
Palmar-plantar erythrodysaesthesia syndrome | 10.12 | 9.93 | 123 | 480502 | 20942 | 55790500 |
Thrombosis | 10.12 | 9.93 | 612 | 480013 | 58815 | 55752627 |
Toxic nodular goitre | 10.11 | 9.93 | 5 | 480620 | 25 | 55811417 |
Limb deformity | 10.09 | 9.93 | 11 | 480614 | 3884 | 55807558 |
Psoriatic arthropathy | 10.08 | 9.93 | 748 | 479877 | 73260 | 55738182 |
Spontaneous haematoma | 10.08 | 9.93 | 22 | 480603 | 804 | 55810638 |
Stoma site inflammation | 10.08 | 9.93 | 15 | 480610 | 404 | 55811038 |
Pericarditis | 10.07 | 9.93 | 1070 | 479555 | 107853 | 55703589 |
Anal polyp | 10.07 | 9.93 | 6 | 480619 | 46 | 55811396 |
Influenza like illness | 10.02 | 9.93 | 422 | 480203 | 60566 | 55750876 |
Vascular stent stenosis | 9.98 | 9.93 | 17 | 480608 | 515 | 55810927 |
Acquired diaphragmatic eventration | 9.97 | 9.93 | 15 | 480610 | 408 | 55811034 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
General physical health deterioration | 928.95 | 10.98 | 2635 | 275758 | 110800 | 31308151 |
Toxicity to various agents | 501.49 | 10.98 | 513 | 277880 | 180974 | 31237977 |
Drug ineffective | 468.29 | 10.98 | 1842 | 276551 | 393731 | 31025220 |
Completed suicide | 411.21 | 10.98 | 145 | 278248 | 91369 | 31327582 |
Chronic kidney disease | 324.53 | 10.98 | 897 | 277496 | 37078 | 31381873 |
Drug abuse | 284.39 | 10.98 | 213 | 278180 | 87545 | 31331406 |
Hypomagnesaemia | 255.45 | 10.98 | 536 | 277857 | 18522 | 31400429 |
Product prescribing error | 220.98 | 10.98 | 515 | 277878 | 19127 | 31399824 |
Haematochezia | 201.62 | 10.98 | 796 | 277597 | 39668 | 31379283 |
Anaemia | 200.02 | 10.98 | 2802 | 275591 | 210720 | 31208231 |
Systemic infection | 196.59 | 10.98 | 194 | 278199 | 3255 | 31415696 |
Hypocalcaemia | 144.10 | 10.98 | 473 | 277920 | 21505 | 31397446 |
Death | 143.50 | 10.98 | 2267 | 276126 | 358302 | 31060649 |
End stage renal disease | 120.42 | 10.98 | 238 | 278155 | 7871 | 31411080 |
Foetal exposure during pregnancy | 107.61 | 10.98 | 120 | 278273 | 40756 | 31378195 |
Hepatic function abnormal | 105.28 | 10.98 | 124 | 278269 | 41098 | 31377853 |
Dyspnoea | 104.80 | 10.98 | 3841 | 274552 | 339638 | 31079313 |
Product monitoring error | 103.58 | 10.98 | 136 | 278257 | 3154 | 31415797 |
Electrolyte imbalance | 94.98 | 10.98 | 278 | 278115 | 11870 | 31407081 |
Intentional overdose | 94.88 | 10.98 | 135 | 278258 | 41254 | 31377697 |
Acute kidney injury | 92.63 | 10.98 | 3158 | 275235 | 276556 | 31142395 |
Off label use | 92.46 | 10.98 | 2334 | 276059 | 344940 | 31074011 |
Cholestasis | 91.17 | 10.98 | 449 | 277944 | 24626 | 31394325 |
Renal injury | 91.11 | 10.98 | 252 | 278141 | 10413 | 31408538 |
Overdose | 87.93 | 10.98 | 413 | 277980 | 84251 | 31334700 |
Intentional product misuse | 79.12 | 10.98 | 132 | 278261 | 37819 | 31381132 |
Abdominal pain upper | 77.63 | 10.98 | 882 | 277511 | 63120 | 31355831 |
Drug resistance | 77.09 | 10.98 | 56 | 278337 | 23397 | 31395554 |
Treatment failure | 76.88 | 10.98 | 151 | 278242 | 40641 | 31378310 |
Melaena | 76.32 | 10.98 | 520 | 277873 | 32134 | 31386817 |
Hypokalaemia | 76.03 | 10.98 | 762 | 277631 | 52812 | 31366139 |
Haematemesis | 73.95 | 10.98 | 431 | 277962 | 25222 | 31393729 |
Gastrooesophageal reflux disease | 73.09 | 10.98 | 529 | 277864 | 33342 | 31385609 |
Abdominal pain lower | 72.25 | 10.98 | 212 | 278181 | 9064 | 31409887 |
Syncope | 70.46 | 10.98 | 1095 | 277298 | 84087 | 31334864 |
Abdominal pain | 66.43 | 10.98 | 1715 | 276678 | 144237 | 31274714 |
Oedema peripheral | 66.28 | 10.98 | 1343 | 277050 | 108496 | 31310455 |
Neuropathy peripheral | 63.10 | 10.98 | 397 | 277996 | 75252 | 31343699 |
Respiratory arrest | 62.83 | 10.98 | 83 | 278310 | 26174 | 31392777 |
Product dose omission issue | 60.77 | 10.98 | 613 | 277780 | 104973 | 31313978 |
Blood loss anaemia | 57.82 | 10.98 | 174 | 278219 | 7545 | 31411406 |
Agranulocytosis | 57.41 | 10.98 | 351 | 278042 | 20896 | 31398055 |
Cardiac arrest | 57.26 | 10.98 | 503 | 277890 | 88559 | 31330392 |
Dyspnoea at rest | 55.30 | 10.98 | 106 | 278287 | 3425 | 31415526 |
Hypoparathyroidism | 55.09 | 10.98 | 43 | 278350 | 518 | 31418433 |
Product use in unapproved indication | 54.91 | 10.98 | 581 | 277812 | 98590 | 31320361 |
Premature baby | 54.51 | 10.98 | 47 | 278346 | 18019 | 31400932 |
Irritability | 54.11 | 10.98 | 73 | 278320 | 22816 | 31396135 |
Atrial fibrillation | 53.80 | 10.98 | 1344 | 277049 | 112439 | 31306512 |
Erysipelas | 53.69 | 10.98 | 121 | 278272 | 4392 | 31414559 |
Diastolic dysfunction | 52.62 | 10.98 | 133 | 278260 | 5202 | 31413749 |
Normocytic anaemia | 51.49 | 10.98 | 76 | 278317 | 1973 | 31416978 |
Abnormal behaviour | 50.48 | 10.98 | 82 | 278311 | 23746 | 31395205 |
Pallor | 49.98 | 10.98 | 353 | 278040 | 22071 | 31396880 |
Febrile infection | 48.28 | 10.98 | 74 | 278319 | 1988 | 31416963 |
Acute abdomen | 46.99 | 10.98 | 68 | 278325 | 1733 | 31417218 |
Gastrointestinal haemorrhage | 46.71 | 10.98 | 1000 | 277393 | 81549 | 31337402 |
Hepatitis cholestatic | 46.11 | 10.98 | 153 | 278240 | 6993 | 31411958 |
Prostate cancer | 46.09 | 10.98 | 172 | 278221 | 37429 | 31381522 |
Lower respiratory tract infection | 45.43 | 10.98 | 114 | 278279 | 28123 | 31390828 |
Psychotic disorder | 45.12 | 10.98 | 79 | 278314 | 22214 | 31396737 |
Musculoskeletal pain | 45.11 | 10.98 | 430 | 277963 | 29398 | 31389553 |
Shock haemorrhagic | 44.20 | 10.98 | 192 | 278201 | 9985 | 31408966 |
Type I hypersensitivity | 44.13 | 10.98 | 52 | 278341 | 1076 | 31417875 |
Cardio-respiratory arrest | 43.87 | 10.98 | 270 | 278123 | 51456 | 31367495 |
Cytomegalovirus infection | 43.55 | 10.98 | 95 | 278298 | 24612 | 31394339 |
Suicide attempt | 43.33 | 10.98 | 174 | 278219 | 37074 | 31381877 |
Drug ineffective for unapproved indication | 42.80 | 10.98 | 56 | 278337 | 17734 | 31401217 |
Labelled drug-drug interaction medication error | 42.47 | 10.98 | 228 | 278165 | 12935 | 31406016 |
Infective exacerbation of chronic obstructive airways disease | 42.41 | 10.98 | 63 | 278330 | 1645 | 31417306 |
Sedation | 42.33 | 10.98 | 63 | 278330 | 18902 | 31400049 |
Asthenia | 41.94 | 10.98 | 2393 | 276000 | 222362 | 31196589 |
Feeling abnormal | 41.64 | 10.98 | 311 | 278082 | 56691 | 31362260 |
Neutrophil count decreased | 41.55 | 10.98 | 238 | 278155 | 46156 | 31372795 |
Therapeutic drug monitoring analysis not performed | 41.44 | 10.98 | 35 | 278358 | 475 | 31418476 |
Occult blood | 41.40 | 10.98 | 39 | 278354 | 616 | 31418335 |
Right atrial hypertrophy | 40.91 | 10.98 | 38 | 278355 | 589 | 31418362 |
Hypoparathyroidism secondary | 40.40 | 10.98 | 21 | 278372 | 115 | 31418836 |
Agitation | 40.31 | 10.98 | 294 | 278099 | 53875 | 31365076 |
Immune reconstitution inflammatory syndrome | 40.19 | 10.98 | 11 | 278382 | 8167 | 31410784 |
Seizure | 39.50 | 10.98 | 627 | 277766 | 99141 | 31319810 |
Synovitis | 39.50 | 10.98 | 30 | 278363 | 12253 | 31406698 |
Benign prostatic hyperplasia | 38.79 | 10.98 | 222 | 278171 | 12903 | 31406048 |
Dyspnoea exertional | 38.74 | 10.98 | 516 | 277877 | 38321 | 31380630 |
Suicidal ideation | 38.71 | 10.98 | 176 | 278217 | 36230 | 31382721 |
Pathogen resistance | 38.67 | 10.98 | 14 | 278379 | 8687 | 31410264 |
Aggression | 38.63 | 10.98 | 182 | 278211 | 37109 | 31381842 |
Rectal haemorrhage | 38.59 | 10.98 | 488 | 277905 | 35816 | 31383135 |
Disease progression | 37.69 | 10.98 | 563 | 277830 | 89901 | 31329050 |
Insomnia | 37.55 | 10.98 | 596 | 277797 | 94240 | 31324711 |
Platelet count decreased | 37.02 | 10.98 | 715 | 277678 | 109720 | 31309231 |
Gastrointestinal bacterial overgrowth | 36.74 | 10.98 | 18 | 278375 | 85 | 31418866 |
Aortic valve stenosis | 36.57 | 10.98 | 72 | 278321 | 2374 | 31416577 |
Helicobacter gastritis | 36.52 | 10.98 | 49 | 278344 | 1161 | 31417790 |
Injection site pain | 36.48 | 10.98 | 168 | 278225 | 34466 | 31384485 |
Bronchial wall thickening | 35.98 | 10.98 | 48 | 278345 | 1131 | 31417820 |
Leukopenia | 35.81 | 10.98 | 710 | 277683 | 57118 | 31361833 |
Rash maculo-papular | 35.59 | 10.98 | 364 | 278029 | 25355 | 31393596 |
Psoriasis | 35.52 | 10.98 | 252 | 278141 | 46467 | 31372484 |
Mucosal haemorrhage | 35.25 | 10.98 | 55 | 278338 | 1501 | 31417450 |
Tricuspid valve incompetence | 34.91 | 10.98 | 162 | 278231 | 8667 | 31410284 |
C-reactive protein increased | 34.87 | 10.98 | 611 | 277782 | 48039 | 31370912 |
Drug reaction with eosinophilia and systemic symptoms | 34.72 | 10.98 | 410 | 277983 | 29608 | 31389343 |
Exposure during pregnancy | 34.69 | 10.98 | 16 | 278377 | 8582 | 31410369 |
Malaise | 34.48 | 10.98 | 1173 | 277220 | 167338 | 31251613 |
Rash | 34.26 | 10.98 | 1434 | 276959 | 200052 | 31218899 |
Hypertensive nephropathy | 34.13 | 10.98 | 30 | 278363 | 431 | 31418520 |
Haematoma | 34.06 | 10.98 | 343 | 278050 | 23796 | 31395155 |
Bronchial secretion retention | 33.80 | 10.98 | 49 | 278344 | 1251 | 31417700 |
Gastritis | 33.44 | 10.98 | 298 | 278095 | 19994 | 31398957 |
Visual acuity reduced | 33.25 | 10.98 | 52 | 278341 | 15291 | 31403660 |
Dizziness | 33.10 | 10.98 | 2099 | 276294 | 197048 | 31221903 |
Adjustment disorder | 32.40 | 10.98 | 45 | 278348 | 1103 | 31417848 |
Stomatitis | 32.33 | 10.98 | 208 | 278185 | 39230 | 31379721 |
Drug withdrawal syndrome | 32.31 | 10.98 | 73 | 278320 | 18677 | 31400274 |
Therapy partial responder | 31.93 | 10.98 | 9 | 278384 | 6553 | 31412398 |
Cardiac failure | 31.79 | 10.98 | 984 | 277409 | 84969 | 31333982 |
Serotonin syndrome | 31.61 | 10.98 | 74 | 278319 | 18699 | 31400252 |
Low birth weight baby | 31.34 | 10.98 | 11 | 278382 | 6959 | 31411992 |
Interstitial lung disease | 31.09 | 10.98 | 367 | 278026 | 61036 | 31357915 |
Acute graft versus host disease | 30.76 | 10.98 | 8 | 278385 | 6145 | 31412806 |
Drug hypersensitivity | 29.83 | 10.98 | 453 | 277940 | 72146 | 31346805 |
Urogenital haemorrhage | 29.68 | 10.98 | 31 | 278362 | 558 | 31418393 |
Therapy non-responder | 29.44 | 10.98 | 175 | 278218 | 33636 | 31385315 |
Upper gastrointestinal haemorrhage | 29.22 | 10.98 | 322 | 278071 | 22861 | 31396090 |
Nephrogenic anaemia | 29.16 | 10.98 | 60 | 278333 | 2043 | 31416908 |
Tachyarrhythmia | 29.13 | 10.98 | 78 | 278315 | 3161 | 31415790 |
Intentional self-injury | 28.98 | 10.98 | 45 | 278348 | 13270 | 31405681 |
Rheumatoid arthritis | 28.97 | 10.98 | 274 | 278119 | 47535 | 31371416 |
Solar lentigo | 28.60 | 10.98 | 28 | 278365 | 465 | 31418486 |
Cerebral infarction | 28.57 | 10.98 | 124 | 278269 | 25853 | 31393098 |
Hyperlipasaemia | 28.08 | 10.98 | 28 | 278365 | 476 | 31418475 |
Chronic graft versus host disease | 27.92 | 10.98 | 3 | 278390 | 4389 | 31414562 |
Wrong technique in product usage process | 27.77 | 10.98 | 175 | 278218 | 33168 | 31385783 |
Therapeutic response decreased | 27.67 | 10.98 | 129 | 278264 | 26380 | 31392571 |
Angina pectoris | 27.59 | 10.98 | 389 | 278004 | 29252 | 31389699 |
Bladder cancer | 27.31 | 10.98 | 55 | 278338 | 14670 | 31404281 |
Dysplastic naevus | 27.21 | 10.98 | 27 | 278366 | 456 | 31418495 |
Bronchiectasis | 27.02 | 10.98 | 135 | 278258 | 7445 | 31411506 |
Injection site haemorrhage | 26.97 | 10.98 | 24 | 278369 | 9061 | 31409890 |
Pulmonary function test abnormal | 26.93 | 10.98 | 60 | 278333 | 2161 | 31416790 |
Fracture | 26.90 | 10.98 | 118 | 278275 | 6162 | 31412789 |
Subileus | 26.88 | 10.98 | 72 | 278321 | 2918 | 31416033 |
Accidental exposure to product | 26.83 | 10.98 | 37 | 278356 | 11458 | 31407493 |
Post transplant lymphoproliferative disorder | 26.62 | 10.98 | 10 | 278383 | 6066 | 31412885 |
Vertigo | 26.56 | 10.98 | 315 | 278078 | 22770 | 31396181 |
Haematoma muscle | 26.43 | 10.98 | 42 | 278351 | 1165 | 31417786 |
Joint swelling | 26.42 | 10.98 | 321 | 278072 | 53110 | 31365841 |
Eosinophilia | 26.19 | 10.98 | 316 | 278077 | 22937 | 31396014 |
Right ventricular hypertrophy | 26.15 | 10.98 | 43 | 278350 | 1228 | 31417723 |
Serum ferritin decreased | 26.00 | 10.98 | 29 | 278364 | 564 | 31418387 |
Photodermatosis | 25.94 | 10.98 | 27 | 278366 | 484 | 31418467 |
Diverticulum intestinal | 25.85 | 10.98 | 80 | 278313 | 3523 | 31415428 |
Troponin increased | 25.62 | 10.98 | 163 | 278230 | 9839 | 31409112 |
Rhinitis perennial | 25.61 | 10.98 | 22 | 278371 | 306 | 31418645 |
Arrhythmia | 25.36 | 10.98 | 420 | 277973 | 32657 | 31386294 |
Aortic valve incompetence | 25.19 | 10.98 | 106 | 278287 | 5435 | 31413516 |
Injection site erythema | 25.16 | 10.98 | 56 | 278337 | 14406 | 31404545 |
Accidental overdose | 25.15 | 10.98 | 80 | 278313 | 18270 | 31400681 |
Tetanus | 25.12 | 10.98 | 12 | 278381 | 53 | 31418898 |
Full blood count abnormal | 24.88 | 10.98 | 236 | 278157 | 16111 | 31402840 |
Product use issue | 24.76 | 10.98 | 350 | 278043 | 56409 | 31362542 |
Blood pressure fluctuation | 24.75 | 10.98 | 307 | 278086 | 22429 | 31396522 |
Mitral valve incompetence | 24.64 | 10.98 | 209 | 278184 | 13824 | 31405127 |
Congenital hiatus hernia | 24.58 | 10.98 | 28 | 278365 | 558 | 31418393 |
Thrombocytopenia | 24.50 | 10.98 | 1509 | 276884 | 141238 | 31277713 |
Lower gastrointestinal haemorrhage | 24.40 | 10.98 | 145 | 278248 | 8544 | 31410407 |
Hepatocellular injury | 24.36 | 10.98 | 293 | 278100 | 21251 | 31397700 |
Hypersensitivity | 24.22 | 10.98 | 344 | 278049 | 55399 | 31363552 |
Carotid arteriosclerosis | 24.21 | 10.98 | 50 | 278343 | 1707 | 31417244 |
Vitamin B12 deficiency | 24.20 | 10.98 | 77 | 278316 | 3442 | 31415509 |
Hydrocholecystis | 23.99 | 10.98 | 21 | 278372 | 300 | 31418651 |
Body temperature decreased | 23.77 | 10.98 | 181 | 278212 | 11589 | 31407362 |
Liver disorder | 23.68 | 10.98 | 158 | 278235 | 29549 | 31389402 |
Extrapyramidal disorder | 23.59 | 10.98 | 42 | 278351 | 11736 | 31407215 |
Urinary hesitation | 23.51 | 10.98 | 60 | 278333 | 2361 | 31416590 |
Presyncope | 23.38 | 10.98 | 244 | 278149 | 17084 | 31401867 |
Renal cyst | 23.34 | 10.98 | 140 | 278253 | 8276 | 31410675 |
Withdrawal syndrome | 23.28 | 10.98 | 42 | 278351 | 11675 | 31407276 |
Psoriatic arthropathy | 23.05 | 10.98 | 93 | 278300 | 19790 | 31399161 |
Myelosuppression | 22.65 | 10.98 | 62 | 278331 | 14858 | 31404093 |
Glomerular filtration rate decreased | 22.60 | 10.98 | 180 | 278213 | 11685 | 31407266 |
Ventricular arrhythmia | 22.57 | 10.98 | 94 | 278299 | 4797 | 31414154 |
Enthesopathy | 22.56 | 10.98 | 5 | 278388 | 4282 | 31414669 |
Fluid intake reduced | 22.52 | 10.98 | 71 | 278322 | 3158 | 31415793 |
Occupational dermatitis | 22.48 | 10.98 | 12 | 278381 | 70 | 31418881 |
Respiratory tract haemorrhage | 22.43 | 10.98 | 38 | 278355 | 1113 | 31417838 |
Drug use disorder | 22.31 | 10.98 | 4 | 278389 | 3979 | 31414972 |
Therapeutic product effect incomplete | 22.18 | 10.98 | 261 | 278132 | 43435 | 31375516 |
Gastrointestinal angiodysplasia | 22.17 | 10.98 | 27 | 278366 | 579 | 31418372 |
Anaphylactic reaction | 22.17 | 10.98 | 160 | 278233 | 29393 | 31389558 |
Anger | 22.14 | 10.98 | 40 | 278353 | 11113 | 31407838 |
Rebound acid hypersecretion | 22.09 | 10.98 | 13 | 278380 | 94 | 31418857 |
Injection site swelling | 22.04 | 10.98 | 34 | 278359 | 10053 | 31408898 |
Electrocardiogram Q wave abnormal | 22.01 | 10.98 | 22 | 278371 | 375 | 31418576 |
Systolic dysfunction | 22.00 | 10.98 | 58 | 278335 | 2328 | 31416623 |
Depression | 22.00 | 10.98 | 618 | 277775 | 90197 | 31328754 |
Urticaria | 21.91 | 10.98 | 364 | 278029 | 57153 | 31361798 |
Oesophageal carcinoma | 21.78 | 10.98 | 23 | 278370 | 8010 | 31410941 |
Degenerative mitral valve disease | 21.63 | 10.98 | 17 | 278376 | 207 | 31418744 |
Tetany | 21.50 | 10.98 | 28 | 278365 | 644 | 31418307 |
Lactic acidosis | 21.43 | 10.98 | 397 | 277996 | 31540 | 31387411 |
Flushing | 21.23 | 10.98 | 166 | 278227 | 29962 | 31388989 |
Bronchopulmonary aspergillosis | 21.19 | 10.98 | 56 | 278337 | 13578 | 31405373 |
Biliary cirrhosis | 21.12 | 10.98 | 13 | 278380 | 103 | 31418848 |
Fear of disease | 20.85 | 10.98 | 19 | 278374 | 287 | 31418664 |
Hyponatraemia | 20.81 | 10.98 | 819 | 277574 | 72980 | 31345971 |
Osteochondrosis | 20.79 | 10.98 | 32 | 278361 | 863 | 31418088 |
No adverse event | 20.78 | 10.98 | 95 | 278298 | 19530 | 31399421 |
Product storage error | 20.57 | 10.98 | 19 | 278374 | 7047 | 31411904 |
Gastritis erosive | 20.51 | 10.98 | 101 | 278292 | 5538 | 31413413 |
Gamma-glutamyltransferase increased | 20.48 | 10.98 | 351 | 278042 | 27474 | 31391477 |
Mood swings | 20.41 | 10.98 | 21 | 278372 | 7403 | 31411548 |
Victim of child abuse | 20.33 | 10.98 | 32 | 278361 | 880 | 31418071 |
Neuroleptic malignant syndrome | 20.12 | 10.98 | 78 | 278315 | 16791 | 31402160 |
Poisoning | 19.97 | 10.98 | 38 | 278355 | 10353 | 31408598 |
Thrombotic microangiopathy | 19.97 | 10.98 | 32 | 278361 | 9319 | 31409632 |
Obstruction | 19.84 | 10.98 | 52 | 278341 | 2080 | 31416871 |
Colitis microscopic | 19.71 | 10.98 | 50 | 278343 | 1960 | 31416991 |
Cytomegalovirus viraemia | 19.68 | 10.98 | 18 | 278375 | 6707 | 31412244 |
Syringe issue | 19.65 | 10.98 | 9 | 278384 | 4847 | 31414104 |
Weight decreased | 19.55 | 10.98 | 1645 | 276748 | 158307 | 31260644 |
Cardiac failure congestive | 19.54 | 10.98 | 539 | 277854 | 78848 | 31340103 |
Acute graft versus host disease in skin | 19.48 | 10.98 | 9 | 278384 | 4823 | 31414128 |
Nicotine dependence | 19.48 | 10.98 | 23 | 278370 | 477 | 31418474 |
Flatulence | 19.41 | 10.98 | 253 | 278140 | 18695 | 31400256 |
Apparent death | 19.39 | 10.98 | 4 | 278389 | 3601 | 31415350 |
Chest X-ray abnormal | 19.37 | 10.98 | 79 | 278314 | 3994 | 31414957 |
Discontinued product administered | 19.32 | 10.98 | 7 | 278386 | 12 | 31418939 |
Cardiotoxicity | 19.30 | 10.98 | 10 | 278383 | 5017 | 31413934 |
Injection site bruising | 19.29 | 10.98 | 25 | 278368 | 7950 | 31411001 |
Memory impairment | 19.25 | 10.98 | 228 | 278165 | 37902 | 31381049 |
Therapeutic product effect decreased | 19.25 | 10.98 | 181 | 278212 | 31441 | 31387510 |
Mean cell haemoglobin decreased | 19.17 | 10.98 | 41 | 278352 | 1435 | 31417516 |
Fall | 19.14 | 10.98 | 1890 | 276503 | 184199 | 31234752 |
Chest injury | 19.06 | 10.98 | 41 | 278352 | 1441 | 31417510 |
Pancreatic enzyme abnormality | 19.06 | 10.98 | 10 | 278383 | 56 | 31418895 |
Foetal malformation | 19.06 | 10.98 | 13 | 278380 | 125 | 31418826 |
Mania | 19.04 | 10.98 | 32 | 278361 | 9145 | 31409806 |
N-terminal prohormone brain natriuretic peptide increased | 19.04 | 10.98 | 52 | 278341 | 2132 | 31416819 |
Device leakage | 19.02 | 10.98 | 12 | 278381 | 5401 | 31413550 |
Serum ferritin abnormal | 19.01 | 10.98 | 16 | 278377 | 216 | 31418735 |
Iron deficiency anaemia | 18.94 | 10.98 | 144 | 278249 | 9215 | 31409736 |
Hiatus hernia | 18.91 | 10.98 | 115 | 278278 | 6832 | 31412119 |
Altered state of consciousness | 18.84 | 10.98 | 108 | 278285 | 20943 | 31398008 |
Hepatojugular reflux | 18.83 | 10.98 | 24 | 278369 | 540 | 31418411 |
Cold sweat | 18.81 | 10.98 | 142 | 278251 | 9067 | 31409884 |
Blood pressure diastolic abnormal | 18.78 | 10.98 | 77 | 278316 | 3902 | 31415049 |
Haematotoxicity | 18.72 | 10.98 | 21 | 278372 | 7116 | 31411835 |
Drug dependence | 18.55 | 10.98 | 119 | 278274 | 22460 | 31396491 |
Autoimmune colitis | 18.39 | 10.98 | 32 | 278361 | 958 | 31417993 |
Polyneuropathy | 18.35 | 10.98 | 185 | 278208 | 12837 | 31406114 |
Gastrointestinal pain | 18.20 | 10.98 | 60 | 278333 | 2733 | 31416218 |
White blood cell count decreased | 18.16 | 10.98 | 607 | 277786 | 86791 | 31332160 |
Pulmonary valve disease | 18.14 | 10.98 | 18 | 278375 | 304 | 31418647 |
Erectile dysfunction | 18.13 | 10.98 | 97 | 278296 | 19138 | 31399813 |
Pericardial disease | 18.05 | 10.98 | 20 | 278373 | 386 | 31418565 |
Hyperkinesia | 17.87 | 10.98 | 43 | 278350 | 1630 | 31417321 |
Status epilepticus | 17.86 | 10.98 | 51 | 278342 | 12055 | 31406896 |
Graft versus host disease | 17.73 | 10.98 | 41 | 278352 | 10406 | 31408545 |
Miosis | 17.68 | 10.98 | 30 | 278363 | 8540 | 31410411 |
Peripheral arterial occlusive disease | 17.63 | 10.98 | 93 | 278300 | 5240 | 31413711 |
Tendonitis | 17.61 | 10.98 | 30 | 278363 | 8528 | 31410423 |
Dermatitis infected | 17.58 | 10.98 | 11 | 278382 | 90 | 31418861 |
Drug screen false positive | 17.56 | 10.98 | 26 | 278367 | 677 | 31418274 |
Cerebellar ischaemia | 17.54 | 10.98 | 12 | 278381 | 116 | 31418835 |
Disseminated intravascular coagulation | 17.51 | 10.98 | 107 | 278286 | 20430 | 31398521 |
Jaundice | 17.46 | 10.98 | 368 | 278025 | 29919 | 31389032 |
Sexual dysfunction | 17.43 | 10.98 | 16 | 278377 | 5952 | 31412999 |
SARS-CoV-2 antibody test positive | 17.42 | 10.98 | 19 | 278374 | 360 | 31418591 |
Treatment noncompliance | 17.41 | 10.98 | 143 | 278250 | 25541 | 31393410 |
Microcytic anaemia | 17.40 | 10.98 | 49 | 278344 | 2046 | 31416905 |
Lethargy | 17.30 | 10.98 | 237 | 278156 | 38404 | 31380547 |
Left ventricular hypertrophy | 17.26 | 10.98 | 117 | 278276 | 7215 | 31411736 |
Phalangeal hypoplasia | 17.26 | 10.98 | 10 | 278383 | 70 | 31418881 |
Sleep disorder due to a general medical condition | 17.24 | 10.98 | 74 | 278319 | 3828 | 31415123 |
Bronchial obstruction | 17.21 | 10.98 | 39 | 278354 | 1421 | 31417530 |
Pruritus allergic | 17.09 | 10.98 | 15 | 278378 | 215 | 31418736 |
Paresis | 17.02 | 10.98 | 47 | 278346 | 1940 | 31417011 |
Drug eruption | 16.98 | 10.98 | 92 | 278301 | 18095 | 31400856 |
Chronic kidney disease-mineral and bone disorder | 16.82 | 10.98 | 19 | 278374 | 375 | 31418576 |
Urosepsis | 16.75 | 10.98 | 167 | 278226 | 11553 | 31407398 |
Gravitational oedema | 16.66 | 10.98 | 24 | 278369 | 609 | 31418342 |
Dysuria | 16.65 | 10.98 | 303 | 278090 | 23991 | 31394960 |
Alanine aminotransferase abnormal | 16.61 | 10.98 | 7 | 278386 | 3960 | 31414991 |
Abdominal wall haemorrhage | 16.56 | 10.98 | 20 | 278373 | 425 | 31418526 |
Underdose | 16.56 | 10.98 | 56 | 278337 | 12551 | 31406400 |
Mean cell haemoglobin concentration | 16.46 | 10.98 | 8 | 278385 | 37 | 31418914 |
Hyperreflexia | 16.44 | 10.98 | 3 | 278390 | 2946 | 31416005 |
Cardiac aneurysm | 16.41 | 10.98 | 28 | 278365 | 825 | 31418126 |
Somnolence | 16.39 | 10.98 | 710 | 277683 | 98735 | 31320216 |
Abnormal faeces | 16.37 | 10.98 | 60 | 278333 | 2884 | 31416067 |
Saliva altered | 16.36 | 10.98 | 13 | 278380 | 161 | 31418790 |
Jugular vein distension | 16.26 | 10.98 | 24 | 278369 | 623 | 31418328 |
Rectal prolapse | 16.24 | 10.98 | 20 | 278373 | 434 | 31418517 |
Subacute cutaneous lupus erythematosus | 16.05 | 10.98 | 29 | 278364 | 895 | 31418056 |
Drug abuser | 16 | 10.98 | 7 | 278386 | 3873 | 31415078 |
Cachexia | 15.98 | 10.98 | 107 | 278286 | 6572 | 31412379 |
Device dependence | 15.97 | 10.98 | 8 | 278385 | 40 | 31418911 |
Nightmare | 15.88 | 10.98 | 54 | 278339 | 12083 | 31406868 |
Perihepatic abscess | 15.77 | 10.98 | 10 | 278383 | 84 | 31418867 |
Base excess decreased | 15.77 | 10.98 | 14 | 278379 | 204 | 31418747 |
Productive cough | 15.76 | 10.98 | 396 | 277997 | 33144 | 31385807 |
Substance abuse | 15.76 | 10.98 | 24 | 278369 | 7134 | 31411817 |
Hallucination | 15.67 | 10.98 | 300 | 278093 | 46110 | 31372841 |
Procalcitonin abnormal | 15.59 | 10.98 | 18 | 278375 | 364 | 31418587 |
COVID-19 pneumonia | 15.59 | 10.98 | 175 | 278218 | 12480 | 31406471 |
Dysentery | 15.57 | 10.98 | 15 | 278378 | 244 | 31418707 |
Bicytopenia | 15.56 | 10.98 | 47 | 278346 | 2042 | 31416909 |
Alveolar lung disease | 15.56 | 10.98 | 18 | 278375 | 365 | 31418586 |
Bradyarrhythmia | 15.53 | 10.98 | 47 | 278346 | 2044 | 31416907 |
Aortic dilatation | 15.51 | 10.98 | 34 | 278359 | 1211 | 31417740 |
Abnormal dreams | 15.49 | 10.98 | 24 | 278369 | 7084 | 31411867 |
Hyperparathyroidism secondary | 15.41 | 10.98 | 38 | 278355 | 1463 | 31417488 |
Immature granulocyte count increased | 15.37 | 10.98 | 11 | 278382 | 115 | 31418836 |
Intraductal papillary mucinous neoplasm | 15.29 | 10.98 | 21 | 278372 | 509 | 31418442 |
Electrocardiogram QT prolonged | 15.14 | 10.98 | 439 | 277954 | 37548 | 31381403 |
Injection site reaction | 15.13 | 10.98 | 52 | 278341 | 11599 | 31407352 |
Thrombophlebitis | 15.13 | 10.98 | 59 | 278334 | 2921 | 31416030 |
Activated partial thromboplastin time shortened | 15.13 | 10.98 | 20 | 278373 | 467 | 31418484 |
Stenosis | 15.11 | 10.98 | 33 | 278360 | 1172 | 31417779 |
Mucormycosis | 15.04 | 10.98 | 16 | 278377 | 5554 | 31413397 |
Duodenogastric reflux | 14.98 | 10.98 | 4 | 278389 | 0 | 31418951 |
Uveitis | 14.87 | 10.98 | 23 | 278370 | 6793 | 31412158 |
Hypercholesterolaemia | 14.85 | 10.98 | 121 | 278272 | 7909 | 31411042 |
Reversible airways obstruction | 14.80 | 10.98 | 17 | 278376 | 342 | 31418609 |
Vision blurred | 14.76 | 10.98 | 269 | 278124 | 41646 | 31377305 |
Tuberculosis | 14.76 | 10.98 | 32 | 278361 | 8309 | 31410642 |
Procalcitonin increased | 14.75 | 10.98 | 40 | 278353 | 1633 | 31417318 |
Drug intolerance | 14.75 | 10.98 | 346 | 278047 | 51687 | 31367264 |
Faeces pale | 14.75 | 10.98 | 34 | 278359 | 1253 | 31417698 |
Eosinophilic pneumonia | 14.67 | 10.98 | 60 | 278333 | 3037 | 31415914 |
Impaired work ability | 14.66 | 10.98 | 18 | 278375 | 5859 | 31413092 |
Hypertrophy | 14.62 | 10.98 | 19 | 278374 | 436 | 31418515 |
Burns second degree | 14.61 | 10.98 | 17 | 278376 | 347 | 31418604 |
Incorrect route of product administration | 14.56 | 10.98 | 53 | 278340 | 11620 | 31407331 |
Dehydration | 14.55 | 10.98 | 1225 | 277168 | 117886 | 31301065 |
Pulpitis dental | 14.53 | 10.98 | 18 | 278375 | 393 | 31418558 |
Injection site phlebitis | 14.46 | 10.98 | 7 | 278386 | 32 | 31418919 |
Disinhibition | 14.46 | 10.98 | 3 | 278390 | 2690 | 31416261 |
Generalised tonic-clonic seizure | 14.42 | 10.98 | 109 | 278284 | 19822 | 31399129 |
Appendicitis | 14.34 | 10.98 | 52 | 278341 | 11413 | 31407538 |
Adverse event | 14.26 | 10.98 | 87 | 278306 | 16618 | 31402333 |
Product quality issue | 14.23 | 10.98 | 83 | 278310 | 16028 | 31402923 |
Hypertransaminasaemia | 14.19 | 10.98 | 75 | 278318 | 4229 | 31414722 |
Mastitis | 14.14 | 10.98 | 12 | 278381 | 164 | 31418787 |
Dependence on oxygen therapy | 14.13 | 10.98 | 13 | 278380 | 199 | 31418752 |
Lichenoid keratosis | 14.03 | 10.98 | 49 | 278344 | 2299 | 31416652 |
Benign gastrointestinal neoplasm | 13.99 | 10.98 | 11 | 278382 | 134 | 31418817 |
Poisoning deliberate | 13.99 | 10.98 | 27 | 278366 | 7317 | 31411634 |
Intestinal angioedema | 13.97 | 10.98 | 13 | 278380 | 202 | 31418749 |
Anxiety | 13.97 | 10.98 | 655 | 277738 | 90378 | 31328573 |
Headache | 13.97 | 10.98 | 1406 | 276987 | 182246 | 31236705 |
Peripheral venous disease | 13.84 | 10.98 | 50 | 278343 | 2386 | 31416565 |
Physical examination abnormal | 13.77 | 10.98 | 15 | 278378 | 284 | 31418667 |
Cellulitis | 13.69 | 10.98 | 319 | 278074 | 47699 | 31371252 |
Activated partial thromboplastin time prolonged | 13.66 | 10.98 | 121 | 278272 | 8104 | 31410847 |
Osteonecrosis | 13.66 | 10.98 | 69 | 278324 | 13815 | 31405136 |
Renal cyst haemorrhage | 13.65 | 10.98 | 21 | 278372 | 566 | 31418385 |
Shock | 13.62 | 10.98 | 130 | 278263 | 22515 | 31396436 |
Dermatosis | 13.60 | 10.98 | 15 | 278378 | 288 | 31418663 |
Periarthritis calcarea | 13.59 | 10.98 | 9 | 278384 | 82 | 31418869 |
Internal fixation of fracture | 13.59 | 10.98 | 9 | 278384 | 82 | 31418869 |
Pancreatitis acute | 13.47 | 10.98 | 307 | 278086 | 25293 | 31393658 |
Stress | 13.43 | 10.98 | 147 | 278246 | 24794 | 31394157 |
Upper motor neurone lesion | 13.33 | 10.98 | 10 | 278383 | 113 | 31418838 |
Articular calcification | 13.33 | 10.98 | 9 | 278384 | 85 | 31418866 |
Puncture site haematoma | 13.22 | 10.98 | 11 | 278382 | 146 | 31418805 |
Actinic keratosis | 13.22 | 10.98 | 72 | 278321 | 4107 | 31414844 |
Bone marrow failure | 13.19 | 10.98 | 170 | 278223 | 27838 | 31391113 |
Blindness | 13.14 | 10.98 | 61 | 278332 | 12490 | 31406461 |
Renal cancer | 13.14 | 10.98 | 30 | 278363 | 7649 | 31411302 |
Fatigue | 13.14 | 10.98 | 3225 | 275168 | 331981 | 31086970 |
Unintentional medical device removal | 13.14 | 10.98 | 3 | 278390 | 2517 | 31416434 |
Paranoia | 13.11 | 10.98 | 48 | 278345 | 10507 | 31408444 |
Device issue | 13.07 | 10.98 | 35 | 278358 | 8449 | 31410502 |
Urinary straining | 13 | 10.98 | 5 | 278388 | 11 | 31418940 |
Myelocyte count increased | 13.00 | 10.98 | 16 | 278377 | 347 | 31418604 |
Hallucination, auditory | 12.95 | 10.98 | 47 | 278346 | 10313 | 31408638 |
Stoma site discharge | 12.91 | 10.98 | 27 | 278366 | 930 | 31418021 |
Epidural lipomatosis | 12.85 | 10.98 | 24 | 278369 | 760 | 31418191 |
Phlebitis infective | 12.84 | 10.98 | 10 | 278383 | 120 | 31418831 |
Haematuria | 12.82 | 10.98 | 513 | 277880 | 45801 | 31373150 |
Vasculitis | 12.79 | 10.98 | 123 | 278270 | 8427 | 31410524 |
Fibrin D dimer increased | 12.73 | 10.98 | 62 | 278331 | 3384 | 31415567 |
Granulomatous dermatitis | 12.67 | 10.98 | 13 | 278380 | 229 | 31418722 |
Left ventricular enlargement | 12.66 | 10.98 | 22 | 278371 | 658 | 31418293 |
Taste disorder | 12.62 | 10.98 | 89 | 278304 | 5561 | 31413390 |
Paranasal sinus discomfort | 12.61 | 10.98 | 23 | 278370 | 715 | 31418236 |
Exercise tolerance decreased | 12.61 | 10.98 | 77 | 278316 | 4581 | 31414370 |
Nasal oedema | 12.59 | 10.98 | 15 | 278378 | 314 | 31418637 |
Blood pressure increased | 12.58 | 10.98 | 836 | 277557 | 78797 | 31340154 |
Vitamin D decreased | 12.57 | 10.98 | 57 | 278336 | 3020 | 31415931 |
Symmetrical drug-related intertriginous and flexural exanthema | 12.56 | 10.98 | 14 | 278379 | 272 | 31418679 |
Rhythm idioventricular | 12.56 | 10.98 | 14 | 278379 | 272 | 31418679 |
Neoplasm malignant | 12.56 | 10.98 | 106 | 278287 | 18825 | 31400126 |
Cough | 12.53 | 10.98 | 1360 | 277033 | 133454 | 31285497 |
Obstructive airways disorder | 12.52 | 10.98 | 168 | 278225 | 12496 | 31406455 |
Blood iron decreased | 12.36 | 10.98 | 77 | 278316 | 4613 | 31414338 |
Rales | 12.30 | 10.98 | 123 | 278270 | 8516 | 31410435 |
Alanine aminotransferase increased | 12.30 | 10.98 | 533 | 277860 | 74123 | 31344828 |
Xyphoid retraction | 12.30 | 10.98 | 11 | 278382 | 162 | 31418789 |
Hypovolaemic shock | 12.29 | 10.98 | 98 | 278295 | 6364 | 31412587 |
Pneumonia aspiration | 12.27 | 10.98 | 253 | 278140 | 38473 | 31380478 |
Acute generalised exanthematous pustulosis | 12.26 | 10.98 | 93 | 278300 | 5947 | 31413004 |
Arteriosclerotic gangrene | 12.25 | 10.98 | 8 | 278385 | 71 | 31418880 |
Confabulation | 12.25 | 10.98 | 10 | 278383 | 129 | 31418822 |
Electrocardiogram abnormal | 12.22 | 10.98 | 116 | 278277 | 7920 | 31411031 |
Myocardial infarction | 12.18 | 10.98 | 845 | 277548 | 112609 | 31306342 |
Sinusitis | 12.15 | 10.98 | 238 | 278155 | 36458 | 31382493 |
Leptospirosis | 12.14 | 10.98 | 6 | 278387 | 29 | 31418922 |
Soft tissue haemorrhage | 12.13 | 10.98 | 10 | 278383 | 131 | 31418820 |
Painful respiration | 12.05 | 10.98 | 30 | 278363 | 1162 | 31417789 |
Anaemia macrocytic | 12.05 | 10.98 | 54 | 278339 | 2846 | 31416105 |
Forced expiratory volume decreased | 12.05 | 10.98 | 55 | 278338 | 2922 | 31416029 |
Blood pressure systolic increased | 12.03 | 10.98 | 239 | 278154 | 19231 | 31399720 |
Nasal polyps | 12.02 | 10.98 | 42 | 278351 | 1971 | 31416980 |
Nocardiosis | 12.02 | 10.98 | 8 | 278385 | 3499 | 31415452 |
Prolonged expiration | 11.97 | 10.98 | 11 | 278382 | 168 | 31418783 |
Dysmorphism | 11.96 | 10.98 | 6 | 278387 | 3066 | 31415885 |
Nuchal rigidity | 11.95 | 10.98 | 18 | 278375 | 476 | 31418475 |
Vena cava injury | 11.94 | 10.98 | 14 | 278379 | 288 | 31418663 |
Pneumonia cytomegaloviral | 11.94 | 10.98 | 5 | 278388 | 2839 | 31416112 |
Leptotrichia infection | 11.89 | 10.98 | 8 | 278385 | 75 | 31418876 |
Haemoglobin decreased | 11.80 | 10.98 | 1146 | 277247 | 111529 | 31307422 |
Blood pressure systolic abnormal | 11.73 | 10.98 | 56 | 278337 | 3031 | 31415920 |
Anaemia of malignant disease | 11.73 | 10.98 | 17 | 278376 | 434 | 31418517 |
Haemorrhoids | 11.72 | 10.98 | 163 | 278230 | 12219 | 31406732 |
Vascular compression | 11.72 | 10.98 | 15 | 278378 | 339 | 31418612 |
Mood altered | 11.71 | 10.98 | 36 | 278357 | 8310 | 31410641 |
Splenic thrombosis | 11.68 | 10.98 | 5 | 278388 | 16 | 31418935 |
Peripheral paralysis | 11.67 | 10.98 | 6 | 278387 | 32 | 31418919 |
Clostridium difficile infection | 11.66 | 10.98 | 215 | 278178 | 17064 | 31401887 |
Occupational exposure to air contaminants | 11.65 | 10.98 | 10 | 278383 | 139 | 31418812 |
Vascular access site occlusion | 11.63 | 10.98 | 7 | 278386 | 53 | 31418898 |
Device malfunction | 11.60 | 10.98 | 42 | 278351 | 9224 | 31409727 |
Arteriovenous fistula | 11.57 | 10.98 | 27 | 278366 | 1003 | 31417948 |
Pancreatic duct stenosis | 11.56 | 10.98 | 11 | 278382 | 176 | 31418775 |
Tobacco abuse | 11.56 | 10.98 | 16 | 278377 | 391 | 31418560 |
Vascular anastomotic haemorrhage | 11.53 | 10.98 | 13 | 278380 | 256 | 31418695 |
Cytomegalovirus chorioretinitis | 11.51 | 10.98 | 8 | 278385 | 3420 | 31415531 |
Lymph node calcification | 11.47 | 10.98 | 10 | 278383 | 142 | 31418809 |
Varicose vein | 11.44 | 10.98 | 29 | 278364 | 1136 | 31417815 |
Angioedema | 11.44 | 10.98 | 217 | 278176 | 33401 | 31385550 |
Foetal growth restriction | 11.42 | 10.98 | 10 | 278383 | 3805 | 31415146 |
Carotid artery stenosis | 11.41 | 10.98 | 75 | 278318 | 4577 | 31414374 |
Hypochromic anaemia | 11.38 | 10.98 | 23 | 278370 | 773 | 31418178 |
Graft versus host disease in skin | 11.29 | 10.98 | 9 | 278384 | 3588 | 31415363 |
Hospitalisation | 11.28 | 10.98 | 342 | 278051 | 49465 | 31369486 |
Wound haemorrhage | 11.27 | 10.98 | 39 | 278354 | 1821 | 31417130 |
Hypergammaglobulinaemia | 11.27 | 10.98 | 12 | 278381 | 221 | 31418730 |
Organic brain syndrome | 11.26 | 10.98 | 13 | 278380 | 263 | 31418688 |
Portal fibrosis | 11.26 | 10.98 | 14 | 278379 | 307 | 31418644 |
Hypogammaglobulinaemia | 11.25 | 10.98 | 26 | 278367 | 6601 | 31412350 |
Cardiovascular somatic symptom disorder | 11.24 | 10.98 | 6 | 278387 | 35 | 31418916 |
Achlorhydria | 11.23 | 10.98 | 3 | 278390 | 0 | 31418951 |
Spinal cord herniation | 11.23 | 10.98 | 3 | 278390 | 0 | 31418951 |
Band neutrophil count decreased | 11.23 | 10.98 | 3 | 278390 | 0 | 31418951 |
Bladder diverticulitis | 11.23 | 10.98 | 3 | 278390 | 0 | 31418951 |
Fibrin D dimer | 11.23 | 10.98 | 3 | 278390 | 0 | 31418951 |
Multiple sclerosis relapse | 11.22 | 10.98 | 61 | 278332 | 11986 | 31406965 |
Arthritis | 11.19 | 10.98 | 171 | 278222 | 27214 | 31391737 |
Acute coronary syndrome | 11.17 | 10.98 | 166 | 278227 | 12623 | 31406328 |
Lung neoplasm malignant | 11.16 | 10.98 | 90 | 278303 | 16140 | 31402811 |
Pulmonary tuberculosis | 11.16 | 10.98 | 15 | 278378 | 4696 | 31414255 |
Schizophrenia | 11.13 | 10.98 | 53 | 278340 | 10777 | 31408174 |
Granulocytopenia | 11.12 | 10.98 | 23 | 278370 | 6076 | 31412875 |
Akathisia | 11.11 | 10.98 | 30 | 278363 | 7223 | 31411728 |
Brain stem ischaemia | 11.10 | 10.98 | 9 | 278384 | 115 | 31418836 |
Pulmonary valve incompetence | 11.08 | 10.98 | 23 | 278370 | 788 | 31418163 |
Meralgia paraesthetica | 11.08 | 10.98 | 10 | 278383 | 149 | 31418802 |
Pulmonary interstitial emphysema syndrome | 11.08 | 10.98 | 17 | 278376 | 457 | 31418494 |
Hypertensive crisis | 11.07 | 10.98 | 116 | 278277 | 8131 | 31410820 |
Bile duct stone | 11.06 | 10.98 | 46 | 278347 | 2346 | 31416605 |
Polypectomy | 11.05 | 10.98 | 18 | 278375 | 510 | 31418441 |
Hyperalbuminaemia | 11.04 | 10.98 | 5 | 278388 | 19 | 31418932 |
Macrocytosis | 11.03 | 10.98 | 25 | 278368 | 911 | 31418040 |
Myoglobin blood increased | 10.98 | 10.98 | 4 | 278389 | 2473 | 31416478 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
General physical health deterioration | 1644.18 | 10.15 | 5205 | 622432 | 230826 | 70069981 |
Toxicity to various agents | 1096.36 | 10.15 | 1060 | 626577 | 381112 | 69919695 |
Completed suicide | 1009.12 | 10.15 | 374 | 627263 | 226761 | 70074046 |
Drug ineffective | 630.27 | 10.15 | 5312 | 622325 | 934440 | 69366367 |
Haematochezia | 501.40 | 10.15 | 1605 | 626032 | 71476 | 70229331 |
Product prescribing error | 458.03 | 10.15 | 1044 | 626593 | 37908 | 70262899 |
Drug abuse | 387.03 | 10.15 | 439 | 627198 | 146817 | 70153990 |
Hypomagnesaemia | 385.82 | 10.15 | 1005 | 626632 | 39759 | 70261048 |
Anaemia | 380.77 | 10.15 | 5335 | 622302 | 398088 | 69902719 |
Chronic kidney disease | 352.73 | 10.15 | 1266 | 626371 | 59791 | 70241016 |
Systemic infection | 306.26 | 10.15 | 335 | 627302 | 6322 | 70294485 |
Intentional overdose | 276.97 | 10.15 | 277 | 627360 | 98158 | 70202649 |
Hypocalcaemia | 231.42 | 10.15 | 897 | 626740 | 43962 | 70256845 |
Exposure during pregnancy | 230.95 | 10.15 | 261 | 627376 | 87456 | 70213351 |
Death | 219.55 | 10.15 | 3185 | 624452 | 506876 | 69793931 |
Dyspnoea | 219.40 | 10.15 | 8604 | 619033 | 761456 | 69539351 |
Abdominal pain upper | 217.23 | 10.15 | 2644 | 624993 | 190958 | 70109849 |
Off label use | 194.84 | 10.15 | 5048 | 622589 | 738012 | 69562795 |
Product monitoring error | 193.27 | 10.15 | 268 | 627369 | 6508 | 70294299 |
Injection site pain | 174.46 | 10.15 | 500 | 627137 | 117119 | 70183688 |
Injection site erythema | 173.05 | 10.15 | 235 | 627402 | 72689 | 70228118 |
Hepatic function abnormal | 170.76 | 10.15 | 210 | 627427 | 67786 | 70233021 |
Abdominal pain | 169.03 | 10.15 | 4091 | 623546 | 338036 | 69962771 |
Acute kidney injury | 165.19 | 10.15 | 5427 | 622210 | 469197 | 69831610 |
Haematemesis | 162.40 | 10.15 | 857 | 626780 | 47940 | 70252867 |
Drug resistance | 156.22 | 10.15 | 71 | 627566 | 38119 | 70262688 |
Overdose | 156.18 | 10.15 | 872 | 626765 | 168873 | 70131934 |
Asthenia | 155.63 | 10.15 | 5219 | 622418 | 452447 | 69848360 |
Folliculitis | 154.48 | 10.15 | 766 | 626871 | 41804 | 70259003 |
Muscle injury | 152.95 | 10.15 | 711 | 626926 | 37783 | 70263024 |
Melaena | 152.19 | 10.15 | 936 | 626701 | 55419 | 70245388 |
Irritable bowel syndrome | 151.74 | 10.15 | 867 | 626770 | 49983 | 70250824 |
Device expulsion | 143.26 | 10.15 | 15 | 627622 | 22231 | 70278576 |
Injection site reaction | 141.68 | 10.15 | 139 | 627498 | 49713 | 70251094 |
Respiratory arrest | 138.15 | 10.15 | 164 | 627473 | 53769 | 70247038 |
Cardio-respiratory arrest | 136.45 | 10.15 | 446 | 627191 | 100231 | 70200576 |
Hyponatraemia | 135.90 | 10.15 | 2080 | 625557 | 158007 | 70142800 |
Electrolyte imbalance | 134.38 | 10.15 | 532 | 627105 | 26329 | 70274478 |
Hypokalaemia | 132.32 | 10.15 | 1757 | 625880 | 129431 | 70171376 |
Labelled drug-drug interaction medication error | 131.47 | 10.15 | 491 | 627146 | 23636 | 70277171 |
Sleep disorder due to general medical condition, insomnia type | 127.56 | 10.15 | 640 | 626997 | 35092 | 70265715 |
Agranulocytosis | 127.48 | 10.15 | 698 | 626939 | 39600 | 70261207 |
Drug hypersensitivity | 126.31 | 10.15 | 1601 | 626036 | 260858 | 70039949 |
Cholestasis | 121.72 | 10.15 | 783 | 626854 | 47089 | 70253718 |
Impaired healing | 119.23 | 10.15 | 1092 | 626545 | 73282 | 70227525 |
End stage renal disease | 118.43 | 10.15 | 287 | 627350 | 10846 | 70289961 |
Product dose omission issue | 118.34 | 10.15 | 1291 | 626346 | 216177 | 70084630 |
Neuropathy peripheral | 117.72 | 10.15 | 650 | 626987 | 126246 | 70174561 |
Wrong technique in product usage process | 116.44 | 10.15 | 273 | 627364 | 68425 | 70232382 |
Injection site swelling | 116.23 | 10.15 | 126 | 627511 | 43031 | 70257776 |
Sedation | 114.54 | 10.15 | 147 | 627490 | 46584 | 70254223 |
Intentional product misuse | 113.92 | 10.15 | 344 | 627293 | 79251 | 70221556 |
Treatment failure | 110.13 | 10.15 | 784 | 626853 | 143358 | 70157449 |
Suicide attempt | 104.47 | 10.15 | 357 | 627280 | 79153 | 70221654 |
Product use in unapproved indication | 104.17 | 10.15 | 1254 | 626383 | 206224 | 70094583 |
Pallor | 99.80 | 10.15 | 663 | 626974 | 40311 | 70260496 |
Blood loss anaemia | 95.21 | 10.15 | 313 | 627324 | 14128 | 70286679 |
Cardiac arrest | 95.06 | 10.15 | 929 | 626708 | 158905 | 70141902 |
Neutrophil count decreased | 91.90 | 10.15 | 403 | 627234 | 83153 | 70217654 |
Subacute cutaneous lupus erythematosus | 91.52 | 10.15 | 127 | 627510 | 3086 | 70297721 |
Gastrointestinal haemorrhage | 88.88 | 10.15 | 1709 | 625928 | 135699 | 70165108 |
Suicidal ideation | 88.40 | 10.15 | 317 | 627320 | 69279 | 70231528 |
Gastrooesophageal reflux disease | 86.40 | 10.15 | 1204 | 626433 | 89635 | 70211172 |
Accidental exposure to product | 85.90 | 10.15 | 73 | 627564 | 27978 | 70272829 |
Abdominal pain lower | 85.43 | 10.15 | 483 | 627154 | 27733 | 70273074 |
Abortion spontaneous | 83.45 | 10.15 | 67 | 627570 | 26412 | 70274395 |
Injection site pruritus | 82.69 | 10.15 | 137 | 627500 | 39073 | 70261734 |
Oedema peripheral | 81.14 | 10.15 | 2616 | 625021 | 225475 | 70075332 |
Eosinophilia | 81.12 | 10.15 | 623 | 627014 | 39696 | 70261111 |
Leukopenia | 78.25 | 10.15 | 1352 | 626285 | 105208 | 70195599 |
Seizure | 78.13 | 10.15 | 1106 | 626531 | 176856 | 70123951 |
Myelosuppression | 76.84 | 10.15 | 92 | 627545 | 30053 | 70270754 |
Therapeutic drug monitoring analysis not performed | 76.83 | 10.15 | 81 | 627556 | 1463 | 70299344 |
Orthostatic intolerance | 76.25 | 10.15 | 86 | 627551 | 1681 | 70299126 |
Syncope | 74.99 | 10.15 | 1959 | 625678 | 163750 | 70137057 |
Therapeutic response decreased | 74.40 | 10.15 | 266 | 627371 | 58187 | 70242620 |
Drug reaction with eosinophilia and systemic symptoms | 74.22 | 10.15 | 813 | 626824 | 57200 | 70243607 |
Maternal exposure during pregnancy | 73.91 | 10.15 | 658 | 626979 | 114687 | 70186120 |
Therapeutic product effect incomplete | 73.30 | 10.15 | 692 | 626945 | 119190 | 70181617 |
Rheumatoid arthritis | 73.02 | 10.15 | 1994 | 625643 | 289811 | 70010996 |
Night sweats | 71.83 | 10.15 | 645 | 626992 | 43039 | 70257768 |
Musculoskeletal pain | 71.44 | 10.15 | 1160 | 626477 | 89167 | 70211640 |
Injection site bruising | 71.18 | 10.15 | 143 | 627494 | 37889 | 70262918 |
Hepatitis cholestatic | 71.07 | 10.15 | 260 | 627377 | 12390 | 70288417 |
Anaphylactic reaction | 68.99 | 10.15 | 385 | 627252 | 74589 | 70226218 |
Acute abdomen | 68.77 | 10.15 | 105 | 627532 | 2789 | 70298018 |
Abnormal behaviour | 68.01 | 10.15 | 127 | 627510 | 34582 | 70266225 |
Hypoparathyroidism secondary | 67.62 | 10.15 | 34 | 627603 | 170 | 70300637 |
Malaise | 67.22 | 10.15 | 3138 | 624499 | 429794 | 69871013 |
Drug ineffective for unapproved indication | 67.03 | 10.15 | 151 | 627486 | 38387 | 70262420 |
Renal injury | 66.69 | 10.15 | 301 | 627336 | 15793 | 70285014 |
Atrial fibrillation | 65.97 | 10.15 | 2116 | 625521 | 182232 | 70118575 |
Drug intolerance | 65.95 | 10.15 | 1507 | 626130 | 224180 | 70076627 |
White blood cell count decreased | 65.93 | 10.15 | 1083 | 626554 | 169058 | 70131749 |
Febrile infection | 65.85 | 10.15 | 107 | 627530 | 3002 | 70297805 |
Platelet count decreased | 65.63 | 10.15 | 1145 | 626492 | 177077 | 70123730 |
Helicobacter infection | 64.02 | 10.15 | 764 | 626873 | 54892 | 70245915 |
Disease progression | 63.80 | 10.15 | 988 | 626649 | 155684 | 70145123 |
Gastritis | 62.72 | 10.15 | 637 | 627000 | 43954 | 70256853 |
Intentional self-injury | 61.84 | 10.15 | 116 | 627521 | 31534 | 70269273 |
Irritability | 61.54 | 10.15 | 156 | 627481 | 38069 | 70262738 |
Enthesopathy | 59.21 | 10.15 | 12 | 627625 | 10857 | 70289950 |
Post transplant lymphoproliferative disorder | 58.80 | 10.15 | 11 | 627626 | 10534 | 70290273 |
Sedation complication | 57.93 | 10.15 | 23 | 627614 | 13387 | 70287420 |
Injection site haemorrhage | 57.82 | 10.15 | 85 | 627552 | 25442 | 70275365 |
Angina pectoris | 57.79 | 10.15 | 669 | 626968 | 47714 | 70253093 |
Premature delivery | 57.58 | 10.15 | 62 | 627575 | 21242 | 70279565 |
Cytomegalovirus infection | 57.47 | 10.15 | 171 | 627466 | 39587 | 70261220 |
Hypoparathyroidism | 57.36 | 10.15 | 57 | 627580 | 957 | 70299850 |
Feeling abnormal | 56.09 | 10.15 | 903 | 626734 | 141416 | 70159391 |
Cellulitis | 55.08 | 10.15 | 584 | 627053 | 98344 | 70202463 |
Haematoma | 54.53 | 10.15 | 662 | 626975 | 47756 | 70253051 |
Drug dependence | 54.32 | 10.15 | 160 | 627477 | 37161 | 70263646 |
Flushing | 54.30 | 10.15 | 465 | 627172 | 81707 | 70219100 |
Ill-defined disorder | 54.26 | 10.15 | 731 | 626906 | 54010 | 70246797 |
Depression | 53.88 | 10.15 | 1344 | 626293 | 197630 | 70103177 |
Gastrointestinal disorder | 53.52 | 10.15 | 1266 | 626371 | 104161 | 70196646 |
Tubulointerstitial nephritis | 53.17 | 10.15 | 486 | 627151 | 32590 | 70268217 |
Diastolic dysfunction | 53.09 | 10.15 | 194 | 627443 | 9239 | 70291568 |
Muscle spasticity | 52.50 | 10.15 | 326 | 627311 | 19363 | 70281444 |
Serotonin syndrome | 51.39 | 10.15 | 195 | 627442 | 41919 | 70258888 |
Acute graft versus host disease | 51.18 | 10.15 | 11 | 627626 | 9551 | 70291256 |
Pathogen resistance | 50.80 | 10.15 | 27 | 627610 | 13252 | 70287555 |
Blister | 50.68 | 10.15 | 1206 | 626431 | 99320 | 70201487 |
Fracture | 50.56 | 10.15 | 326 | 627311 | 19618 | 70281189 |
Duodenal ulcer perforation | 50.44 | 10.15 | 682 | 626955 | 50430 | 70250377 |
Shock haemorrhagic | 50.31 | 10.15 | 303 | 627334 | 17803 | 70283004 |
Prostate cancer | 49.54 | 10.15 | 128 | 627509 | 31035 | 70269772 |
Dehydration | 49.38 | 10.15 | 2461 | 625176 | 223681 | 70077126 |
Peripheral swelling | 49.12 | 10.15 | 2562 | 625075 | 234001 | 70066806 |
Unintentional medical device removal | 48.01 | 10.15 | 4 | 627633 | 7120 | 70293687 |
Dyspnoea exertional | 47.17 | 10.15 | 965 | 626672 | 77465 | 70223342 |
Drug eruption | 46.83 | 10.15 | 185 | 627452 | 39311 | 70261496 |
Confusional state | 46.40 | 10.15 | 3014 | 624623 | 281384 | 70019423 |
Rectal haemorrhage | 46.08 | 10.15 | 829 | 626808 | 65002 | 70235805 |
Mydriasis | 45.94 | 10.15 | 45 | 627592 | 16108 | 70284699 |
Product use issue | 45.89 | 10.15 | 1226 | 626411 | 178711 | 70122096 |
Psoriasis | 45.59 | 10.15 | 605 | 627032 | 97828 | 70202979 |
Poisoning | 45.01 | 10.15 | 82 | 627555 | 22540 | 70278267 |
Aortic valve stenosis | 44.61 | 10.15 | 120 | 627517 | 4839 | 70295968 |
Drug use disorder | 44.40 | 10.15 | 9 | 627628 | 8142 | 70292665 |
Haemoglobin decreased | 44.23 | 10.15 | 2230 | 625407 | 202929 | 70097878 |
Therapy partial responder | 43.98 | 10.15 | 28 | 627609 | 12446 | 70288361 |
Hypoaesthesia | 43.93 | 10.15 | 1030 | 626607 | 152709 | 70148098 |
Therapy non-responder | 43.65 | 10.15 | 452 | 627185 | 76463 | 70224344 |
Coma | 43.46 | 10.15 | 562 | 627075 | 91282 | 70209525 |
Lower respiratory tract infection | 43.31 | 10.15 | 1297 | 626340 | 110616 | 70190191 |
Ear pain | 43.09 | 10.15 | 403 | 627234 | 27196 | 70273611 |
Cachexia | 42.41 | 10.15 | 187 | 627450 | 9713 | 70291094 |
Injection site warmth | 42.31 | 10.15 | 36 | 627601 | 13789 | 70287018 |
Fall | 42.12 | 10.15 | 4517 | 623120 | 439579 | 69861228 |
Hypertensive nephropathy | 41.98 | 10.15 | 45 | 627592 | 829 | 70299978 |
Product storage error | 41.94 | 10.15 | 40 | 627597 | 14501 | 70286306 |
Device use error | 41.89 | 10.15 | 5 | 627632 | 6691 | 70294116 |
Helicobacter gastritis | 41.52 | 10.15 | 75 | 627562 | 2296 | 70298511 |
Body temperature decreased | 41.48 | 10.15 | 412 | 627225 | 28260 | 70272547 |
Polyneuropathy | 40.92 | 10.15 | 327 | 627310 | 21088 | 70279719 |
Adverse drug reaction | 40.78 | 10.15 | 290 | 627347 | 53054 | 70247753 |
Dyspnoea at rest | 40.73 | 10.15 | 143 | 627494 | 6676 | 70294131 |
Breast cancer female | 40.59 | 10.15 | 21 | 627616 | 10465 | 70290342 |
Right atrial hypertrophy | 40.51 | 10.15 | 38 | 627599 | 592 | 70300215 |
No adverse event | 40.46 | 10.15 | 147 | 627490 | 32006 | 70268801 |
Breath sounds abnormal | 40.39 | 10.15 | 227 | 627410 | 13004 | 70287803 |
Agitation | 40.35 | 10.15 | 582 | 627055 | 92793 | 70208014 |
Device issue | 40.28 | 10.15 | 96 | 627541 | 23929 | 70276878 |
Psychotic disorder | 40.14 | 10.15 | 184 | 627453 | 37517 | 70263290 |
Hepatocellular injury | 39.88 | 10.15 | 601 | 627036 | 45490 | 70255317 |
Somnolence | 39.84 | 10.15 | 1532 | 626105 | 214074 | 70086733 |
Shock | 39.73 | 10.15 | 203 | 627434 | 40222 | 70260585 |
Aggression | 39.71 | 10.15 | 258 | 627379 | 48188 | 70252619 |
Neuroleptic malignant syndrome | 39.69 | 10.15 | 109 | 627528 | 25898 | 70274909 |
Status epilepticus | 39.55 | 10.15 | 100 | 627537 | 24426 | 70276381 |
Poisoning deliberate | 39.44 | 10.15 | 56 | 627581 | 17004 | 70283803 |
Benign prostatic hyperplasia | 39.37 | 10.15 | 190 | 627447 | 10253 | 70290554 |
Interstitial lung disease | 39.34 | 10.15 | 670 | 626967 | 104015 | 70196792 |
Lung diffusion test abnormal | 38.99 | 10.15 | 26 | 627611 | 238 | 70300569 |
Bladder cancer | 38.48 | 10.15 | 58 | 627579 | 17184 | 70283623 |
Erysipelas | 38.46 | 10.15 | 182 | 627455 | 9742 | 70291065 |
Caesarean section | 38.32 | 10.15 | 28 | 627609 | 11579 | 70289228 |
Multiple-drug resistance | 38.28 | 10.15 | 9 | 627628 | 7346 | 70293461 |
Tachyarrhythmia | 38.26 | 10.15 | 134 | 627503 | 6248 | 70294559 |
Normocytic anaemia | 37.99 | 10.15 | 93 | 627544 | 3537 | 70297270 |
Pre-eclampsia | 37.84 | 10.15 | 6 | 627631 | 6479 | 70294328 |
Drug withdrawal syndrome | 37.68 | 10.15 | 155 | 627482 | 32560 | 70268247 |
Disseminated intravascular coagulation | 37.57 | 10.15 | 161 | 627476 | 33437 | 70267370 |
Discontinued product administered | 37.55 | 10.15 | 16 | 627621 | 50 | 70300757 |
Hyperkinesia | 37.36 | 10.15 | 76 | 627561 | 2547 | 70298260 |
Rash maculo-papular | 37.34 | 10.15 | 642 | 626995 | 49903 | 70250904 |
Faecaloma | 37.16 | 10.15 | 187 | 627450 | 10264 | 70290543 |
Blood pressure systolic increased | 36.94 | 10.15 | 712 | 626925 | 56547 | 70244260 |
Dysuria | 36.90 | 10.15 | 590 | 627047 | 45204 | 70255603 |
Thrombocytopenia | 36.83 | 10.15 | 2522 | 625115 | 236588 | 70064219 |
Gamma-glutamyltransferase increased | 36.80 | 10.15 | 642 | 626995 | 50043 | 70250764 |
Presyncope | 36.30 | 10.15 | 498 | 627139 | 36940 | 70263867 |
Gestational diabetes | 36.29 | 10.15 | 5 | 627632 | 5996 | 70294811 |
Cytomegalovirus viraemia | 36.28 | 10.15 | 30 | 627607 | 11655 | 70289152 |
Jaundice | 36.13 | 10.15 | 634 | 627003 | 49474 | 70251333 |
Infective exacerbation of chronic obstructive airways disease | 36.05 | 10.15 | 73 | 627564 | 2438 | 70298369 |
Device difficult to use | 36.04 | 10.15 | 26 | 627611 | 10823 | 70289984 |
Gastrointestinal bacterial overgrowth | 35.45 | 10.15 | 30 | 627607 | 405 | 70300402 |
Upper gastrointestinal haemorrhage | 35.32 | 10.15 | 496 | 627141 | 36981 | 70263826 |
Type I hypersensitivity | 35.29 | 10.15 | 92 | 627545 | 3640 | 70297167 |
Mobility decreased | 34.68 | 10.15 | 672 | 626965 | 102327 | 70198480 |
Vomiting | 34.52 | 10.15 | 5859 | 621778 | 587252 | 69713555 |
Neutropenic sepsis | 34.32 | 10.15 | 109 | 627528 | 24721 | 70276086 |
Vertigo | 34.19 | 10.15 | 760 | 626877 | 61883 | 70238924 |
Tetany | 34.13 | 10.15 | 67 | 627570 | 2187 | 70298620 |
Gastrointestinal pain | 33.95 | 10.15 | 155 | 627482 | 8172 | 70292635 |
Extrapyramidal disorder | 33.93 | 10.15 | 84 | 627553 | 20666 | 70280141 |
Body temperature increased | 33.92 | 10.15 | 518 | 627119 | 39316 | 70261491 |
Fluid intake reduced | 33.85 | 10.15 | 118 | 627519 | 5489 | 70295318 |
Treatment noncompliance | 33.78 | 10.15 | 257 | 627380 | 46317 | 70254490 |
Foetal exposure during pregnancy | 33.45 | 10.15 | 5 | 627632 | 5640 | 70295167 |
Mucosal haemorrhage | 33.37 | 10.15 | 69 | 627568 | 2340 | 70298467 |
Subileus | 33.31 | 10.15 | 112 | 627525 | 5115 | 70295692 |
Hiatus hernia | 33.19 | 10.15 | 309 | 627328 | 20825 | 70279982 |
Flatulence | 32.70 | 10.15 | 497 | 627140 | 37684 | 70263123 |
Gastritis erosive | 32.69 | 10.15 | 176 | 627461 | 9919 | 70290888 |
Photodermatosis | 32.62 | 10.15 | 41 | 627596 | 902 | 70299905 |
Blood pressure diastolic abnormal | 32.55 | 10.15 | 242 | 627395 | 15262 | 70285545 |
Vision blurred | 32.50 | 10.15 | 618 | 627019 | 94366 | 70206441 |
Injection site urticaria | 32.43 | 10.15 | 33 | 627604 | 11605 | 70289202 |
Painful respiration | 32.32 | 10.15 | 81 | 627556 | 3127 | 70297680 |
Injection site rash | 32.19 | 10.15 | 60 | 627577 | 16350 | 70284457 |
Paresis | 32.18 | 10.15 | 91 | 627546 | 3779 | 70297028 |
Pneumonia aspiration | 32.17 | 10.15 | 374 | 627263 | 61915 | 70238892 |
Depressed level of consciousness | 32.07 | 10.15 | 562 | 627075 | 86869 | 70213938 |
Tongue disorder | 32.00 | 10.15 | 42 | 627595 | 13185 | 70287622 |
Granuloma skin | 31.86 | 10.15 | 14 | 627623 | 7668 | 70293139 |
Cerebral infarction | 31.82 | 10.15 | 236 | 627401 | 42773 | 70258034 |
Urogenital haemorrhage | 31.50 | 10.15 | 37 | 627600 | 757 | 70300050 |
Glomerular filtration rate decreased | 31.37 | 10.15 | 301 | 627336 | 20455 | 70280352 |
Bronchopulmonary aspergillosis | 31.32 | 10.15 | 89 | 627548 | 20913 | 70279894 |
Sinusitis | 31.27 | 10.15 | 1813 | 625824 | 167382 | 70133425 |
Hypochromic anaemia | 31.11 | 10.15 | 69 | 627568 | 2458 | 70298349 |
Red blood cell sedimentation rate increased | 31.06 | 10.15 | 207 | 627430 | 38435 | 70262372 |
Bursitis | 31.04 | 10.15 | 367 | 627270 | 26306 | 70274501 |
Balance disorder | 30.96 | 10.15 | 586 | 627051 | 89542 | 70211265 |
Epstein-Barr virus infection | 30.83 | 10.15 | 43 | 627594 | 13155 | 70287652 |
Myocardial infarction | 30.75 | 10.15 | 1224 | 626413 | 170421 | 70130386 |
Cardiac failure congestive | 30.70 | 10.15 | 938 | 626699 | 134519 | 70166288 |
Musculoskeletal stiffness | 30.67 | 10.15 | 1035 | 626602 | 146725 | 70154082 |
Medication error | 30.60 | 10.15 | 689 | 626948 | 56223 | 70244584 |
Visual acuity reduced | 30.52 | 10.15 | 135 | 627502 | 27795 | 70273012 |
Haematotoxicity | 30.52 | 10.15 | 46 | 627591 | 13628 | 70287179 |
Breast cancer | 30.46 | 10.15 | 173 | 627464 | 33376 | 70267431 |
Cardiac failure | 30.46 | 10.15 | 1558 | 626079 | 141983 | 70158824 |
Lethargy | 30.46 | 10.15 | 475 | 627162 | 74775 | 70226032 |
Weight increased | 30.44 | 10.15 | 2515 | 625122 | 239816 | 70060991 |
Alcohol interaction | 30.32 | 10.15 | 3 | 627634 | 4650 | 70296157 |
Iron deficiency anaemia | 30.27 | 10.15 | 325 | 627312 | 22747 | 70278060 |
Diverticulum intestinal | 30.10 | 10.15 | 146 | 627491 | 7895 | 70292912 |
Alopecia | 30.07 | 10.15 | 1442 | 626195 | 197048 | 70103759 |
Withdrawal syndrome | 29.94 | 10.15 | 116 | 627521 | 24788 | 70276019 |
Alanine aminotransferase abnormal | 29.94 | 10.15 | 17 | 627620 | 8042 | 70292765 |
Anxiety | 29.86 | 10.15 | 1619 | 626018 | 218711 | 70082096 |
Sickle cell anaemia with crisis | 29.79 | 10.15 | 8 | 627629 | 5970 | 70294837 |
Tricuspid valve incompetence | 29.76 | 10.15 | 264 | 627373 | 17553 | 70283254 |
Schizophrenia | 29.73 | 10.15 | 65 | 627572 | 16703 | 70284104 |
Exposure to toxic agent | 29.55 | 10.15 | 9 | 627628 | 6185 | 70294622 |
Urosepsis | 29.43 | 10.15 | 333 | 627304 | 23616 | 70277191 |
Adenovirus infection | 29.42 | 10.15 | 16 | 627621 | 7752 | 70293055 |
Pyrexia | 29.41 | 10.15 | 5940 | 621697 | 601012 | 69699795 |
Oesophageal carcinoma | 29.14 | 10.15 | 24 | 627613 | 9342 | 70291465 |
Hydrocholecystis | 28.52 | 10.15 | 25 | 627612 | 355 | 70300452 |
Tuberculosis | 28.50 | 10.15 | 55 | 627582 | 14793 | 70286014 |
Joint stiffness | 28.49 | 10.15 | 188 | 627449 | 34988 | 70265819 |
Contusion | 28.47 | 10.15 | 1396 | 626241 | 126640 | 70174167 |
Pain in jaw | 28.39 | 10.15 | 241 | 627396 | 42428 | 70258379 |
Product quality issue | 28.07 | 10.15 | 157 | 627480 | 30404 | 70270403 |
Exposure via ingestion | 27.68 | 10.15 | 5 | 627632 | 4910 | 70295897 |
Haematocrit decreased | 27.66 | 10.15 | 683 | 626954 | 56575 | 70244232 |
Diarrhoea | 27.62 | 10.15 | 7556 | 620081 | 775785 | 69525022 |
Dystonia | 27.59 | 10.15 | 86 | 627551 | 19620 | 70281187 |
Underdose | 27.51 | 10.15 | 150 | 627487 | 29233 | 70271574 |
Dyspepsia | 27.44 | 10.15 | 1005 | 626632 | 88072 | 70212735 |
Carotid arteriosclerosis | 27.36 | 10.15 | 64 | 627573 | 2363 | 70298444 |
Chronic graft versus host disease | 27.05 | 10.15 | 13 | 627624 | 6757 | 70294050 |
Blood parathyroid hormone decreased | 27.00 | 10.15 | 24 | 627613 | 9000 | 70291807 |
Mucormycosis | 26.89 | 10.15 | 19 | 627618 | 7995 | 70292812 |
Genital haemorrhage | 26.77 | 10.15 | 9 | 627628 | 5806 | 70295001 |
Fear of injection | 26.37 | 10.15 | 13 | 627624 | 6659 | 70294148 |
Trimethylaminuria | 26.29 | 10.15 | 17 | 627620 | 147 | 70300660 |
Eructation | 26.27 | 10.15 | 162 | 627475 | 9598 | 70291209 |
Restlessness | 26.21 | 10.15 | 521 | 627116 | 41607 | 70259200 |
Gastrointestinal angiodysplasia | 26.20 | 10.15 | 38 | 627599 | 963 | 70299844 |
Hyperammonaemic encephalopathy | 26.18 | 10.15 | 4 | 627633 | 4439 | 70296368 |
Substance abuse | 26.17 | 10.15 | 29 | 627608 | 9808 | 70290999 |
Osteonecrosis | 26.14 | 10.15 | 151 | 627486 | 29009 | 70271798 |
Coagulation test abnormal | 26.11 | 10.15 | 42 | 627595 | 1168 | 70299639 |
Pulmonary function test abnormal | 26.04 | 10.15 | 78 | 627559 | 3347 | 70297460 |
Clostridium test positive | 26.00 | 10.15 | 98 | 627539 | 4738 | 70296069 |
Immune reconstitution inflammatory syndrome | 25.92 | 10.15 | 47 | 627590 | 12943 | 70287864 |
Abnormal faeces | 25.80 | 10.15 | 121 | 627516 | 6452 | 70294355 |
Pulmonary tuberculosis | 25.80 | 10.15 | 19 | 627618 | 7826 | 70292981 |
Lactic acidosis | 25.80 | 10.15 | 756 | 626881 | 64268 | 70236539 |
Colitis erosive | 25.78 | 10.15 | 15 | 627622 | 105 | 70300702 |
Rebound acid hypersecretion | 25.68 | 10.15 | 14 | 627623 | 85 | 70300722 |
Uterine perforation | 25.62 | 10.15 | 10 | 627627 | 5881 | 70294926 |
Device malfunction | 25.53 | 10.15 | 85 | 627552 | 18999 | 70281808 |
Peripheral venous disease | 25.46 | 10.15 | 172 | 627465 | 10515 | 70290292 |
Tendonitis | 25.36 | 10.15 | 105 | 627532 | 22017 | 70278790 |
Gastroenteritis clostridial | 25.07 | 10.15 | 34 | 627603 | 808 | 70299999 |
Joint injury | 24.93 | 10.15 | 138 | 627499 | 26794 | 70274013 |
Tetanus | 24.86 | 10.15 | 12 | 627625 | 54 | 70300753 |
Red blood cell count decreased | 24.84 | 10.15 | 621 | 627016 | 51540 | 70249267 |
Colorectal cancer | 24.78 | 10.15 | 23 | 627614 | 8447 | 70292360 |
Obstructive airways disorder | 24.77 | 10.15 | 346 | 627291 | 25767 | 70275040 |
Mood swings | 24.77 | 10.15 | 81 | 627556 | 18205 | 70282602 |
Duodenitis | 24.69 | 10.15 | 125 | 627512 | 6877 | 70293930 |
Hypertensive crisis | 24.65 | 10.15 | 270 | 627367 | 18992 | 70281815 |
Rhinitis perennial | 24.61 | 10.15 | 22 | 627615 | 321 | 70300486 |
Nephrogenic anaemia | 24.37 | 10.15 | 79 | 627558 | 3539 | 70297268 |
Gastric ulcer | 24.28 | 10.15 | 406 | 627231 | 31384 | 70269423 |
Urinary hesitation | 24.23 | 10.15 | 80 | 627557 | 3619 | 70297188 |
Premature rupture of membranes | 24.17 | 10.15 | 3 | 627634 | 3895 | 70296912 |
Musculoskeletal disorder | 24.02 | 10.15 | 93 | 627544 | 19878 | 70280929 |
Multiple sclerosis relapse | 23.91 | 10.15 | 254 | 627383 | 42763 | 70258044 |
Asphyxia | 23.85 | 10.15 | 34 | 627603 | 10308 | 70290499 |
Clostridium difficile infection | 23.80 | 10.15 | 479 | 627158 | 38337 | 70262470 |
Panniculitis | 23.74 | 10.15 | 36 | 627601 | 10640 | 70290167 |
Hepatic cyst | 23.69 | 10.15 | 105 | 627532 | 5466 | 70295341 |
Respiratory depression | 23.67 | 10.15 | 126 | 627511 | 24705 | 70276102 |
Pruritus | 23.66 | 10.15 | 3445 | 624192 | 342115 | 69958692 |
Bicytopenia | 23.66 | 10.15 | 84 | 627553 | 3944 | 70296863 |
Dysentery | 23.53 | 10.15 | 36 | 627601 | 958 | 70299849 |
Lower gastrointestinal haemorrhage | 23.51 | 10.15 | 216 | 627421 | 14504 | 70286303 |
Congenital hiatus hernia | 23.50 | 10.15 | 27 | 627610 | 539 | 70300268 |
Productive cough | 23.44 | 10.15 | 881 | 626756 | 77456 | 70223351 |
Stillbirth | 23.42 | 10.15 | 3 | 627634 | 3802 | 70297005 |
Mycotic allergy | 23.39 | 10.15 | 38 | 627599 | 1066 | 70299741 |
Heavy menstrual bleeding | 23.37 | 10.15 | 48 | 627589 | 12617 | 70288190 |
Breast cancer stage II | 23.37 | 10.15 | 9 | 627628 | 5337 | 70295470 |
Food allergy | 23.27 | 10.15 | 142 | 627495 | 8382 | 70292425 |
Solar lentigo | 23.21 | 10.15 | 37 | 627600 | 1021 | 70299786 |
Nausea | 23.17 | 10.15 | 8135 | 619502 | 843953 | 69456854 |
Pancreatic steatosis | 23.16 | 10.15 | 37 | 627600 | 1023 | 70299784 |
Drug tolerance | 23.15 | 10.15 | 19 | 627618 | 7409 | 70293398 |
C-reactive protein increased | 23.12 | 10.15 | 1198 | 626439 | 109319 | 70191488 |
Nightmare | 23.07 | 10.15 | 109 | 627528 | 22047 | 70278760 |
Cardiotoxicity | 23.04 | 10.15 | 39 | 627598 | 11031 | 70289776 |
Weight decreased | 23.04 | 10.15 | 3110 | 624527 | 307378 | 69993429 |
Temperature regulation disorder | 23.02 | 10.15 | 89 | 627548 | 4355 | 70296452 |
Stomatitis | 22.96 | 10.15 | 1373 | 626264 | 127138 | 70173669 |
Haematuria | 22.79 | 10.15 | 730 | 626907 | 62843 | 70237964 |
Arrhythmia | 22.62 | 10.15 | 654 | 626983 | 55489 | 70245318 |
Alanine aminotransferase increased | 22.61 | 10.15 | 1070 | 626567 | 146410 | 70154397 |
Rash | 22.51 | 10.15 | 4076 | 623561 | 506486 | 69794321 |
Product used for unknown indication | 22.43 | 10.15 | 47 | 627590 | 1609 | 70299198 |
Injection site mass | 22.33 | 10.15 | 85 | 627552 | 18258 | 70282549 |
Injection site discolouration | 22.28 | 10.15 | 18 | 627619 | 7074 | 70293733 |
Troponin increased | 22.25 | 10.15 | 235 | 627402 | 16379 | 70284428 |
Accidental overdose | 22.20 | 10.15 | 201 | 627436 | 34920 | 70265887 |
Reactive gastropathy | 22.14 | 10.15 | 24 | 627613 | 448 | 70300359 |
Renal failure | 22.12 | 10.15 | 1952 | 625685 | 187118 | 70113689 |
Dysplastic naevus | 21.98 | 10.15 | 26 | 627611 | 536 | 70300271 |
Generalised tonic-clonic seizure | 21.96 | 10.15 | 249 | 627388 | 41412 | 70259395 |
Colitis ulcerative | 21.94 | 10.15 | 422 | 627215 | 33501 | 70267306 |
Bronchial wall thickening | 21.93 | 10.15 | 55 | 627582 | 2124 | 70298683 |
Paradoxical drug reaction | 21.92 | 10.15 | 16 | 627621 | 6620 | 70294187 |
Osteomyelitis | 21.65 | 10.15 | 168 | 627469 | 30150 | 70270657 |
Wheezing | 21.61 | 10.15 | 1030 | 626607 | 93140 | 70207667 |
Miosis | 21.59 | 10.15 | 59 | 627578 | 14042 | 70286765 |
N-terminal prohormone brain natriuretic peptide increased | 21.50 | 10.15 | 80 | 627557 | 3844 | 70296963 |
Abnormal dreams | 21.48 | 10.15 | 38 | 627599 | 10565 | 70290242 |
Obstruction | 21.44 | 10.15 | 76 | 627561 | 3565 | 70297242 |
Cognitive disorder | 21.34 | 10.15 | 395 | 627242 | 60561 | 70240246 |
Autoimmune colitis | 21.32 | 10.15 | 44 | 627593 | 1490 | 70299317 |
Acute generalised exanthematous pustulosis | 21.19 | 10.15 | 219 | 627418 | 15178 | 70285629 |
Headache | 21.13 | 10.15 | 4679 | 622958 | 575726 | 69725081 |
Peripheral arterial occlusive disease | 21.08 | 10.15 | 126 | 627511 | 7383 | 70293424 |
Exercise tolerance decreased | 21.02 | 10.15 | 135 | 627502 | 8113 | 70292694 |
Tenosynovitis | 21.01 | 10.15 | 59 | 627578 | 13917 | 70286890 |
Dizziness | 21.01 | 10.15 | 4528 | 623109 | 459613 | 69841194 |
Neurotoxicity | 20.96 | 10.15 | 166 | 627471 | 29660 | 70271147 |
Sexual dysfunction | 20.93 | 10.15 | 17 | 627620 | 6664 | 70294143 |
Hyperreflexia | 20.85 | 10.15 | 21 | 627616 | 7421 | 70293386 |
Right ventricular hypertrophy | 20.84 | 10.15 | 42 | 627595 | 1398 | 70299409 |
Therapeutic drug monitoring analysis incorrectly performed | 20.79 | 10.15 | 20 | 627617 | 322 | 70300485 |
Creatinine renal clearance decreased | 20.75 | 10.15 | 80 | 627557 | 17120 | 70283687 |
Cardiorenal syndrome | 20.74 | 10.15 | 43 | 627594 | 1461 | 70299346 |
Graft versus host disease in skin | 20.74 | 10.15 | 12 | 627625 | 5618 | 70295189 |
Dyskinesia | 20.68 | 10.15 | 248 | 627389 | 40826 | 70259981 |
Bone marrow failure | 20.64 | 10.15 | 307 | 627330 | 48703 | 70252104 |
Pancytopenia | 20.55 | 10.15 | 1578 | 626059 | 149529 | 70151278 |
Suspected suicide | 20.42 | 10.15 | 29 | 627608 | 8805 | 70292002 |
Renal cyst | 20.40 | 10.15 | 194 | 627443 | 13151 | 70287656 |
Soft tissue disorder | 20.36 | 10.15 | 71 | 627566 | 3303 | 70297504 |
Cytomegalovirus infection reactivation | 20.33 | 10.15 | 18 | 627619 | 6763 | 70294044 |
Rectal prolapse | 20.20 | 10.15 | 51 | 627586 | 1978 | 70298829 |
Acute graft versus host disease in skin | 20.16 | 10.15 | 20 | 627617 | 7117 | 70293690 |
Vitamin B12 deficiency | 19.94 | 10.15 | 105 | 627532 | 5867 | 70294940 |
Cytomegalovirus chorioretinitis | 19.94 | 10.15 | 11 | 627626 | 5287 | 70295520 |
Pulmonary embolism | 19.93 | 10.15 | 1620 | 626017 | 154247 | 70146560 |
Serum ferritin abnormal | 19.89 | 10.15 | 21 | 627616 | 380 | 70300427 |
Pulmonary valve disease | 19.79 | 10.15 | 18 | 627619 | 269 | 70300538 |
Thrombotic microangiopathy | 19.67 | 10.15 | 86 | 627551 | 17762 | 70283045 |
Paralysis | 19.64 | 10.15 | 49 | 627588 | 12023 | 70288784 |
Osteochondrosis | 19.63 | 10.15 | 44 | 627593 | 1579 | 70299228 |
Hallucination | 19.58 | 10.15 | 519 | 627118 | 75741 | 70225066 |
Sopor | 19.55 | 10.15 | 387 | 627250 | 30880 | 70269927 |
Respiratory tract haemorrhage | 19.49 | 10.15 | 45 | 627592 | 1647 | 70299160 |
Occupational dermatitis | 19.49 | 10.15 | 13 | 627624 | 119 | 70300688 |
Victim of child abuse | 19.48 | 10.15 | 32 | 627605 | 906 | 70299901 |
Degenerative mitral valve disease | 19.47 | 10.15 | 17 | 627620 | 240 | 70300567 |
Adrenal insufficiency | 19.24 | 10.15 | 137 | 627500 | 25058 | 70275749 |
Anal haemorrhage | 19.20 | 10.15 | 76 | 627561 | 3760 | 70297047 |
Lung neoplasm malignant | 19.16 | 10.15 | 134 | 627503 | 24608 | 70276199 |
Akathisia | 19.15 | 10.15 | 51 | 627586 | 12242 | 70288565 |
Hyperkalaemia | 19.08 | 10.15 | 1139 | 626498 | 105452 | 70195355 |
Respiratory disorder | 18.99 | 10.15 | 467 | 627170 | 38656 | 70262151 |
Unevaluable event | 18.98 | 10.15 | 335 | 627302 | 51728 | 70249079 |
Blood pressure systolic abnormal | 18.92 | 10.15 | 186 | 627451 | 12723 | 70288084 |
Intraocular pressure increased | 18.86 | 10.15 | 31 | 627606 | 8870 | 70291937 |
Appendicitis | 18.82 | 10.15 | 80 | 627557 | 16653 | 70284154 |
Mania | 18.77 | 10.15 | 83 | 627554 | 17091 | 70283716 |
Premature labour | 18.75 | 10.15 | 26 | 627611 | 7974 | 70292833 |
Graft versus host disease | 18.69 | 10.15 | 69 | 627568 | 14954 | 70285853 |
Biliary dilatation | 18.69 | 10.15 | 55 | 627582 | 2337 | 70298470 |
Microcytic anaemia | 18.68 | 10.15 | 88 | 627549 | 4701 | 70296106 |
Hepatojugular reflux | 18.66 | 10.15 | 25 | 627612 | 587 | 70300220 |
Synovial fluid analysis | 18.63 | 10.15 | 47 | 627590 | 1822 | 70298985 |
Normal newborn | 18.56 | 10.15 | 17 | 627620 | 6283 | 70294524 |
Altered state of consciousness | 18.52 | 10.15 | 246 | 627391 | 39776 | 70261031 |
Folate deficiency | 18.50 | 10.15 | 64 | 627573 | 2966 | 70297841 |
Faeces pale | 18.49 | 10.15 | 59 | 627578 | 2621 | 70298186 |
Hypertransaminasaemia | 18.44 | 10.15 | 139 | 627498 | 8804 | 70292003 |
Stenosis | 18.36 | 10.15 | 50 | 627587 | 2031 | 70298776 |
Product administered to patient of inappropriate age | 18.30 | 10.15 | 10 | 627627 | 4833 | 70295974 |
Clostridium difficile colitis | 18.17 | 10.15 | 359 | 627278 | 28637 | 70272170 |
Full blood count abnormal | 18.16 | 10.15 | 410 | 627227 | 33468 | 70267339 |
Stress | 18.13 | 10.15 | 460 | 627177 | 67506 | 70233301 |
Multiple sclerosis | 18.11 | 10.15 | 140 | 627497 | 25145 | 70275662 |
Biliary cirrhosis | 18.02 | 10.15 | 14 | 627623 | 166 | 70300641 |
Intracranial mass | 18.01 | 10.15 | 50 | 627587 | 2054 | 70298753 |
Tinnitus | 17.99 | 10.15 | 219 | 627418 | 35957 | 70264850 |
Haematoma muscle | 17.98 | 10.15 | 53 | 627584 | 2254 | 70298553 |
Aortic dilatation | 17.98 | 10.15 | 43 | 627594 | 1611 | 70299196 |
Thrombosis prophylaxis | 17.97 | 10.15 | 7 | 627630 | 16 | 70300791 |
Osteonecrosis of jaw | 17.91 | 10.15 | 255 | 627382 | 40747 | 70260060 |
Pericarditis | 17.88 | 10.15 | 919 | 626718 | 83786 | 70217021 |
Bronchial secretion retention | 17.87 | 10.15 | 63 | 627574 | 2947 | 70297860 |
Pneumonia cytomegaloviral | 17.86 | 10.15 | 9 | 627628 | 4552 | 70296255 |
Dissociation | 17.83 | 10.15 | 4 | 627633 | 3372 | 70297435 |
Insomnia | 17.62 | 10.15 | 1673 | 625964 | 216133 | 70084674 |
Chronic gastritis | 17.62 | 10.15 | 71 | 627566 | 3542 | 70297265 |
Device dependence | 17.59 | 10.15 | 9 | 627628 | 47 | 70300760 |
Bacteriuria | 17.59 | 10.15 | 34 | 627603 | 1097 | 70299710 |
Serum ferritin decreased | 17.56 | 10.15 | 49 | 627588 | 2019 | 70298788 |
Intestinal haemorrhage | 17.53 | 10.15 | 102 | 627535 | 5918 | 70294889 |
Posterior reversible encephalopathy syndrome | 17.53 | 10.15 | 135 | 627502 | 24267 | 70276540 |
Herpes zoster | 17.45 | 10.15 | 598 | 627039 | 84637 | 70216170 |
Nocardiosis | 17.42 | 10.15 | 12 | 627625 | 5117 | 70295690 |
Lymphoproliferative disorder | 17.41 | 10.15 | 13 | 627624 | 5316 | 70295491 |
Hyperparathyroidism secondary | 17.36 | 10.15 | 56 | 627581 | 2502 | 70298305 |
Blood pressure increased | 17.33 | 10.15 | 1914 | 625723 | 186603 | 70114204 |
Organic brain syndrome | 17.31 | 10.15 | 21 | 627616 | 445 | 70300362 |
SARS-CoV-2 antibody test positive | 17.27 | 10.15 | 19 | 627618 | 361 | 70300446 |
Internal haemorrhage | 17.22 | 10.15 | 127 | 627510 | 7989 | 70292818 |
Spinal pain | 17.16 | 10.15 | 192 | 627445 | 13578 | 70287229 |
Abortion induced | 17.12 | 10.15 | 20 | 627617 | 6605 | 70294202 |
Procalcitonin abnormal | 17.10 | 10.15 | 19 | 627618 | 365 | 70300442 |
Wound | 17.10 | 10.15 | 1052 | 626585 | 97680 | 70203127 |
Aortic valve incompetence | 17.03 | 10.15 | 136 | 627501 | 8768 | 70292039 |
Throat clearing | 17.03 | 10.15 | 43 | 627594 | 1668 | 70299139 |
Food aversion | 17.02 | 10.15 | 27 | 627610 | 742 | 70300065 |
Drug dose omission by device | 16.96 | 10.15 | 8 | 627629 | 4204 | 70296603 |
Electroencephalogram abnormal | 16.95 | 10.15 | 13 | 627624 | 5245 | 70295562 |
Incorrect dose administered by device | 16.95 | 10.15 | 9 | 627628 | 4420 | 70296387 |
Drug effective for unapproved indication | 16.90 | 10.15 | 10 | 627627 | 4625 | 70296182 |
Transplant rejection | 16.88 | 10.15 | 93 | 627544 | 18078 | 70282729 |
Systolic dysfunction | 16.87 | 10.15 | 68 | 627569 | 3393 | 70297414 |
Cholecystitis | 16.79 | 10.15 | 267 | 627370 | 20434 | 70280373 |
Amenorrhoea | 16.77 | 10.15 | 22 | 627615 | 6908 | 70293899 |
Delusion | 16.77 | 10.15 | 100 | 627537 | 19065 | 70281742 |
BK virus infection | 16.76 | 10.15 | 28 | 627609 | 7961 | 70292846 |
Hyperlipasaemia | 16.65 | 10.15 | 32 | 627605 | 1028 | 70299779 |
Hepatitis | 16.65 | 10.15 | 569 | 627068 | 49411 | 70251396 |
Glaucoma | 16.58 | 10.15 | 93 | 627544 | 17999 | 70282808 |
Mean cell haemoglobin concentration | 16.57 | 10.15 | 8 | 627629 | 36 | 70300771 |
Accidental death | 16.40 | 10.15 | 7 | 627630 | 3901 | 70296906 |
Gravitational oedema | 16.37 | 10.15 | 43 | 627594 | 1709 | 70299098 |
Vaginal haemorrhage | 16.37 | 10.15 | 109 | 627528 | 20243 | 70280564 |
Hypovolaemic shock | 16.30 | 10.15 | 157 | 627480 | 10680 | 70290127 |
Pericardial disease | 16.28 | 10.15 | 22 | 627615 | 521 | 70300286 |
Activated partial thromboplastin time prolonged | 16.24 | 10.15 | 187 | 627450 | 13318 | 70287489 |
Retroperitoneal haematoma | 16.20 | 10.15 | 87 | 627550 | 4898 | 70295909 |
Disseminated tuberculosis | 16.19 | 10.15 | 8 | 627629 | 4092 | 70296715 |
Loss of personal independence in daily activities | 16.18 | 10.15 | 601 | 627036 | 84309 | 70216498 |
Taste disorder | 16.18 | 10.15 | 163 | 627474 | 11222 | 70289585 |
Complication of device insertion | 16.17 | 10.15 | 14 | 627623 | 5318 | 70295489 |
Rib deformity | 16.14 | 10.15 | 13 | 627624 | 163 | 70300644 |
Tachypnoea | 16.12 | 10.15 | 349 | 627288 | 28289 | 70272518 |
Anosognosia | 16.11 | 10.15 | 3 | 627634 | 2882 | 70297925 |
Frequent bowel movements | 16.10 | 10.15 | 270 | 627367 | 20883 | 70279924 |
Disorientation | 16.05 | 10.15 | 646 | 626991 | 57277 | 70243530 |
Sputum discoloured | 15.99 | 10.15 | 245 | 627392 | 18606 | 70282201 |
Bradycardia | 15.90 | 10.15 | 1295 | 626342 | 123320 | 70177487 |
Fatigue | 15.88 | 10.15 | 7778 | 619859 | 816541 | 69484266 |
Immature granulocyte count increased | 15.87 | 10.15 | 22 | 627615 | 534 | 70300273 |
Pseudomembranous colitis | 15.81 | 10.15 | 88 | 627549 | 5023 | 70295784 |
Pancreatitis | 15.80 | 10.15 | 692 | 626945 | 61976 | 70238831 |
Tenosynovitis stenosans | 15.77 | 10.15 | 51 | 627586 | 2282 | 70298525 |
Device leakage | 15.76 | 10.15 | 37 | 627600 | 9271 | 70291536 |
Cystostomy | 15.71 | 10.15 | 9 | 627628 | 61 | 70300746 |
Tardive dyskinesia | 15.61 | 10.15 | 41 | 627596 | 9888 | 70290919 |
Toxic skin eruption | 15.58 | 10.15 | 258 | 627379 | 19904 | 70280903 |
Electrocardiogram Q wave abnormal | 15.57 | 10.15 | 22 | 627615 | 544 | 70300263 |
Epileptic encephalopathy | 15.54 | 10.15 | 19 | 627618 | 406 | 70300401 |
Adjustment disorder | 15.51 | 10.15 | 62 | 627575 | 3082 | 70297725 |
Pneumonia viral | 15.51 | 10.15 | 126 | 627511 | 8166 | 70292641 |
Meralgia paraesthetica | 15.50 | 10.15 | 19 | 627618 | 407 | 70300400 |
Hepatotoxicity | 15.41 | 10.15 | 285 | 627352 | 43701 | 70257106 |
Waist circumference increased | 15.39 | 10.15 | 38 | 627599 | 1453 | 70299354 |
Sleep disorder due to a general medical condition | 15.38 | 10.15 | 151 | 627486 | 10325 | 70290482 |
Circulatory collapse | 15.34 | 10.15 | 417 | 627220 | 35057 | 70265750 |
Blood pressure fluctuation | 15.18 | 10.15 | 653 | 626984 | 58359 | 70242448 |
Mean cell haemoglobin decreased | 15.17 | 10.15 | 89 | 627548 | 5179 | 70295628 |
Swelling face | 15.15 | 10.15 | 434 | 627203 | 62730 | 70238077 |
Faeces hard | 15.14 | 10.15 | 51 | 627586 | 2331 | 70298476 |
Solar urticaria | 15.02 | 10.15 | 9 | 627628 | 67 | 70300740 |
Pneumocystis jirovecii pneumonia | 15.00 | 10.15 | 182 | 627455 | 29900 | 70270907 |
Hypomania | 14.98 | 10.15 | 19 | 627618 | 6053 | 70294754 |
Cerebellar ischaemia | 14.93 | 10.15 | 12 | 627625 | 150 | 70300657 |
Drug abuser | 14.83 | 10.15 | 18 | 627619 | 5846 | 70294961 |
Abdominal wall haemorrhage | 14.82 | 10.15 | 23 | 627614 | 620 | 70300187 |
Mitral valve incompetence | 14.81 | 10.15 | 325 | 627312 | 26403 | 70274404 |
Haemophagocytic lymphohistiocytosis | 14.80 | 10.15 | 107 | 627530 | 19505 | 70281302 |
Vena cava injury | 14.79 | 10.15 | 16 | 627621 | 298 | 70300509 |
Hepatitis B | 14.76 | 10.15 | 31 | 627606 | 8083 | 70292724 |
Anger | 14.75 | 10.15 | 83 | 627554 | 16049 | 70284758 |
Migraine | 14.74 | 10.15 | 507 | 627130 | 71731 | 70229076 |
Nasal obstruction | 14.72 | 10.15 | 39 | 627598 | 1558 | 70299249 |
Urinary tract infection enterococcal | 14.71 | 10.15 | 61 | 627576 | 3083 | 70297724 |
Premature baby | 14.69 | 10.15 | 6 | 627631 | 3433 | 70297374 |
Ventricular arrhythmia | 14.65 | 10.15 | 119 | 627518 | 7711 | 70293096 |
Monocyte count increased | 14.64 | 10.15 | 135 | 627502 | 9074 | 70291733 |
Blood glucose increased | 14.64 | 10.15 | 753 | 626884 | 102229 | 70198578 |
Skin disorder | 14.63 | 10.15 | 185 | 627452 | 30172 | 70270635 |
Hepatic enzyme increased | 14.58 | 10.15 | 1595 | 626042 | 155395 | 70145412 |
Thrombophlebitis | 14.57 | 10.15 | 96 | 627541 | 5820 | 70294987 |
Arteriosclerotic gangrene | 14.49 | 10.15 | 9 | 627628 | 72 | 70300735 |
Gastrointestinal vascular malformation haemorrhagic | 14.46 | 10.15 | 25 | 627612 | 739 | 70300068 |
Stupor | 14.43 | 10.15 | 22 | 627615 | 6487 | 70294320 |
Retinal haemorrhage | 14.42 | 10.15 | 29 | 627608 | 7681 | 70293126 |
Device deployment issue | 14.41 | 10.15 | 4 | 627633 | 2920 | 70297887 |
Viral mutation identified | 14.40 | 10.15 | 7 | 627630 | 3615 | 70297192 |
Activated partial thromboplastin time shortened | 14.34 | 10.15 | 27 | 627610 | 854 | 70299953 |
Haemorrhagic erosive gastritis | 14.28 | 10.15 | 21 | 627616 | 539 | 70300268 |
Physical examination abnormal | 14.27 | 10.15 | 15 | 627622 | 270 | 70300537 |
Product administered at inappropriate site | 14.24 | 10.15 | 6 | 627631 | 3370 | 70297437 |
Vascular purpura | 14.23 | 10.15 | 55 | 627582 | 2691 | 70298116 |
Cholecystitis chronic | 14.18 | 10.15 | 136 | 627501 | 9240 | 70291567 |
Epigastric discomfort | 14.12 | 10.15 | 111 | 627526 | 7122 | 70293685 |
Perihepatic abscess | 14.12 | 10.15 | 11 | 627626 | 131 | 70300676 |
Confabulation | 14.02 | 10.15 | 19 | 627618 | 451 | 70300356 |
Memory impairment | 14.02 | 10.15 | 673 | 626964 | 91968 | 70208839 |
Polycystic ovaries | 14.02 | 10.15 | 4 | 627633 | 2868 | 70297939 |
Hepatitis B reactivation | 14.02 | 10.15 | 16 | 627621 | 5339 | 70295468 |
Endophthalmitis | 14.00 | 10.15 | 21 | 627616 | 6234 | 70294573 |
Cold sweat | 14.00 | 10.15 | 220 | 627417 | 16796 | 70284011 |
Coronavirus test positive | 13.97 | 10.15 | 30 | 627607 | 1045 | 70299762 |
Influenza like illness | 13.93 | 10.15 | 456 | 627181 | 64875 | 70235932 |
Syringe issue | 13.86 | 10.15 | 16 | 627621 | 5312 | 70295495 |
Cerebral ischaemia | 13.81 | 10.15 | 147 | 627490 | 10265 | 70290542 |
Intraductal papillary mucinous neoplasm | 13.80 | 10.15 | 25 | 627612 | 767 | 70300040 |
Cryptococcosis | 13.78 | 10.15 | 6 | 627631 | 3304 | 70297503 |
Infection | 13.77 | 10.15 | 2096 | 625541 | 208689 | 70092118 |
Intraventricular haemorrhage | 13.76 | 10.15 | 76 | 627561 | 4325 | 70296482 |
Second primary malignancy | 13.71 | 10.15 | 64 | 627573 | 12987 | 70287820 |
Benign gastrointestinal neoplasm | 13.65 | 10.15 | 11 | 627626 | 138 | 70300669 |
Strongyloidiasis | 13.62 | 10.15 | 8 | 627629 | 3715 | 70297092 |
Abdominal wall wound | 13.62 | 10.15 | 9 | 627628 | 81 | 70300726 |
Red blood cell sedimentation rate | 13.59 | 10.15 | 14 | 627623 | 4896 | 70295911 |
Periarthritis calcarea | 13.53 | 10.15 | 9 | 627628 | 82 | 70300725 |
Ventricular fibrillation | 13.53 | 10.15 | 164 | 627473 | 26947 | 70273860 |
Renal cancer | 13.51 | 10.15 | 56 | 627581 | 11740 | 70289067 |
Apparent death | 13.51 | 10.15 | 4 | 627633 | 2800 | 70298007 |
Asthma | 13.49 | 10.15 | 1243 | 626394 | 119550 | 70181257 |
Petit mal epilepsy | 13.47 | 10.15 | 17 | 627620 | 5427 | 70295380 |
Sensory level abnormal | 13.46 | 10.15 | 11 | 627626 | 141 | 70300666 |
Bile duct stone | 13.44 | 10.15 | 85 | 627552 | 5081 | 70295726 |
Rhinitis allergic | 13.42 | 10.15 | 40 | 627597 | 9255 | 70291552 |
Dysphoria | 13.42 | 10.15 | 12 | 627625 | 4486 | 70296321 |
Pancreatic enzyme abnormality | 13.41 | 10.15 | 10 | 627627 | 111 | 70300696 |
Diffuse large B-cell lymphoma recurrent | 13.40 | 10.15 | 7 | 627630 | 3469 | 70297338 |
Somatic symptom disorder | 13.38 | 10.15 | 44 | 627593 | 1986 | 70298821 |
Thinking abnormal | 13.32 | 10.15 | 58 | 627579 | 11993 | 70288814 |
Occult blood | 13.28 | 10.15 | 36 | 627601 | 1458 | 70299349 |
Lipase increased | 13.26 | 10.15 | 199 | 627438 | 15047 | 70285760 |
Complication of device removal | 13.25 | 10.15 | 7 | 627630 | 3447 | 70297360 |
Faecal calprotectin increased | 13.23 | 10.15 | 76 | 627561 | 4389 | 70296418 |
Flank pain | 13.18 | 10.15 | 223 | 627414 | 17279 | 70283528 |
Urine alcohol test positive | 13.17 | 10.15 | 6 | 627631 | 23 | 70300784 |
Cystitis haemorrhagic | 13.12 | 10.15 | 36 | 627601 | 8557 | 70292250 |
Dermatosis | 13.08 | 10.15 | 20 | 627617 | 532 | 70300275 |
Chest X-ray abnormal | 13.06 | 10.15 | 108 | 627529 | 7036 | 70293771 |
Carcinoid tumour of the stomach | 13.05 | 10.15 | 12 | 627625 | 182 | 70300625 |
Stoma site discharge | 13.04 | 10.15 | 40 | 627597 | 1739 | 70299068 |
Alcohol use | 13.03 | 10.15 | 13 | 627624 | 4614 | 70296193 |
Stasis dermatitis | 13.00 | 10.15 | 33 | 627604 | 1284 | 70299523 |
Gastrointestinal toxicity | 12.94 | 10.15 | 23 | 627614 | 6382 | 70294425 |
Upper respiratory tract irritation | 12.91 | 10.15 | 11 | 627626 | 150 | 70300657 |
Hyperprolactinaemia | 12.89 | 10.15 | 12 | 627625 | 4401 | 70296406 |
Dysphagia | 12.89 | 10.15 | 1163 | 626474 | 111671 | 70189136 |
Demyelination | 12.87 | 10.15 | 28 | 627609 | 7208 | 70293599 |
Rapid eye movement sleep behaviour disorder | 12.83 | 10.15 | 16 | 627621 | 349 | 70300458 |
Arterial stenosis | 12.82 | 10.15 | 34 | 627603 | 1359 | 70299448 |
Application site pain | 12.82 | 10.15 | 12 | 627625 | 4390 | 70296417 |
Dental caries | 12.82 | 10.15 | 53 | 627584 | 11118 | 70289689 |
Eosinophils urine present | 12.78 | 10.15 | 8 | 627629 | 65 | 70300742 |
Chronic kidney disease-mineral and bone disorder | 12.78 | 10.15 | 22 | 627615 | 648 | 70300159 |
Glomerulonephropathy | 12.76 | 10.15 | 15 | 627622 | 307 | 70300500 |
Pseudarthrosis | 12.68 | 10.15 | 14 | 627623 | 267 | 70300540 |
Unresponsive to stimuli | 12.66 | 10.15 | 356 | 627281 | 51575 | 70249232 |
Feeling jittery | 12.64 | 10.15 | 157 | 627480 | 11386 | 70289421 |
Facet joint syndrome | 12.60 | 10.15 | 95 | 627542 | 6018 | 70294789 |
Inferior vena cava dilatation | 12.59 | 10.15 | 24 | 627613 | 766 | 70300041 |
Surgery | 12.57 | 10.15 | 188 | 627449 | 29801 | 70271006 |
Mitochondrial toxicity | 12.56 | 10.15 | 5 | 627632 | 2905 | 70297902 |
Crepitations | 12.50 | 10.15 | 125 | 627512 | 8589 | 70292218 |
Chronic sinusitis | 12.50 | 10.15 | 122 | 627515 | 8329 | 70292478 |
Gastrointestinal inflammation | 12.49 | 10.15 | 102 | 627535 | 6621 | 70294186 |
Gingival hypertrophy | 12.47 | 10.15 | 5 | 627632 | 2893 | 70297914 |
Umbilical hernia | 12.46 | 10.15 | 84 | 627553 | 5132 | 70295675 |
Pancreatic duct stenosis | 12.45 | 10.15 | 13 | 627624 | 232 | 70300575 |
Lipoedema | 12.44 | 10.15 | 12 | 627625 | 194 | 70300613 |
Leptospirosis | 12.43 | 10.15 | 6 | 627631 | 27 | 70300780 |
Aspartate aminotransferase increased | 12.40 | 10.15 | 961 | 626676 | 126017 | 70174790 |
Coma scale abnormal | 12.40 | 10.15 | 34 | 627603 | 8082 | 70292725 |
Intermenstrual bleeding | 12.37 | 10.15 | 17 | 627620 | 5233 | 70295574 |
Lumbar vertebral fracture | 12.31 | 10.15 | 93 | 627544 | 5894 | 70294913 |
Inappropriate antidiuretic hormone secretion | 12.26 | 10.15 | 281 | 627356 | 22995 | 70277812 |
Metastatic malignant melanoma | 12.24 | 10.15 | 58 | 627579 | 3106 | 70297701 |
Xyphoid retraction | 12.22 | 10.15 | 11 | 627626 | 162 | 70300645 |
Incorrect route of product administration | 12.20 | 10.15 | 163 | 627474 | 26329 | 70274478 |
Anaphylactic shock | 12.18 | 10.15 | 208 | 627429 | 32282 | 70268525 |
Prothrombin time shortened | 12.17 | 10.15 | 55 | 627582 | 2887 | 70297920 |
Duodenogastric reflux | 12.15 | 10.15 | 7 | 627630 | 48 | 70300759 |
Puncture site haematoma | 12.12 | 10.15 | 11 | 627626 | 164 | 70300643 |
Poor venous access | 12.10 | 10.15 | 193 | 627444 | 14778 | 70286029 |
Renal cyst haemorrhage | 12.09 | 10.15 | 21 | 627616 | 623 | 70300184 |
Salpingo-oophorectomy unilateral | 12.07 | 10.15 | 21 | 627616 | 624 | 70300183 |
Retro-orbital neoplasm | 12.03 | 10.15 | 7 | 627630 | 49 | 70300758 |
Bone disorder | 11.99 | 10.15 | 98 | 627539 | 17392 | 70283415 |
Iron deficiency | 11.98 | 10.15 | 113 | 627524 | 7643 | 70293164 |
Rheumatoid nodule | 11.96 | 10.15 | 81 | 627556 | 14986 | 70285821 |
Bladder hypertrophy | 11.96 | 10.15 | 20 | 627617 | 575 | 70300232 |
Granulocytopenia | 11.92 | 10.15 | 51 | 627586 | 10596 | 70290211 |
Troponin abnormal | 11.88 | 10.15 | 5 | 627632 | 15 | 70300792 |
Internal fixation of fracture | 11.86 | 10.15 | 15 | 627622 | 332 | 70300475 |
Gastroenteritis viral | 11.79 | 10.15 | 127 | 627510 | 21328 | 70279479 |
Enteritis | 11.76 | 10.15 | 169 | 627468 | 12662 | 70288145 |
Left ventricular enlargement | 11.74 | 10.15 | 22 | 627615 | 693 | 70300114 |
Dermatitis exfoliative generalised | 11.74 | 10.15 | 97 | 627540 | 6317 | 70294490 |
Coeliac disease | 11.74 | 10.15 | 127 | 627510 | 8906 | 70291901 |
Left ventricular hypertrophy | 11.71 | 10.15 | 140 | 627497 | 10062 | 70290745 |
Hepatitis acute | 11.67 | 10.15 | 181 | 627456 | 13781 | 70287026 |
Alkalosis | 11.66 | 10.15 | 18 | 627619 | 483 | 70300324 |
Scleritis | 11.63 | 10.15 | 63 | 627574 | 3559 | 70297248 |
Acute respiratory distress syndrome | 11.60 | 10.15 | 277 | 627360 | 40977 | 70259830 |
Maternal exposure before pregnancy | 11.60 | 10.15 | 10 | 627627 | 3806 | 70297001 |
Alveolar lung disease | 11.59 | 10.15 | 19 | 627618 | 537 | 70300270 |
Neurosensory hypoacusis | 11.59 | 10.15 | 12 | 627625 | 212 | 70300595 |
Occupational exposure to air contaminants | 11.58 | 10.15 | 10 | 627627 | 139 | 70300668 |
Bradyarrhythmia | 11.53 | 10.15 | 67 | 627570 | 3886 | 70296921 |
COVID-19 | 11.52 | 10.15 | 793 | 626844 | 104964 | 70195843 |
Blood iron decreased | 11.50 | 10.15 | 173 | 627464 | 13088 | 70287719 |
Injection site induration | 11.48 | 10.15 | 42 | 627595 | 9126 | 70291681 |
Vascular anastomotic haemorrhage | 11.45 | 10.15 | 13 | 627624 | 256 | 70300551 |
Hyperplastic cholecystopathy | 11.35 | 10.15 | 10 | 627627 | 143 | 70300664 |
Vocal cord dysfunction | 11.32 | 10.15 | 17 | 627620 | 445 | 70300362 |
Pneumonitis chemical | 11.30 | 10.15 | 15 | 627622 | 349 | 70300458 |
Skin necrosis | 11.30 | 10.15 | 91 | 627546 | 16200 | 70284607 |
Total lung capacity abnormal | 11.29 | 10.15 | 11 | 627626 | 180 | 70300627 |
Arthritis | 11.29 | 10.15 | 731 | 626906 | 97249 | 70203558 |
Paronychia | 11.29 | 10.15 | 29 | 627608 | 7045 | 70293762 |
Hostility | 11.27 | 10.15 | 3 | 627634 | 2252 | 70298555 |
Periodontitis | 11.25 | 10.15 | 13 | 627624 | 4315 | 70296492 |
Erectile dysfunction | 11.23 | 10.15 | 72 | 627565 | 13490 | 70287317 |
Anuria | 11.22 | 10.15 | 240 | 627397 | 19413 | 70281394 |
Typical aura without headache | 11.21 | 10.15 | 3 | 627634 | 0 | 70300807 |
Vascular dissection | 11.21 | 10.15 | 3 | 627634 | 0 | 70300807 |
Bladder diverticulitis | 11.21 | 10.15 | 3 | 627634 | 0 | 70300807 |
Scrotal inflammation | 11.21 | 10.15 | 3 | 627634 | 0 | 70300807 |
Vascular access site complication | 11.21 | 10.15 | 3 | 627634 | 0 | 70300807 |
Ulcerative duodenitis | 11.21 | 10.15 | 3 | 627634 | 0 | 70300807 |
Anaesthesia oral | 11.21 | 10.15 | 3 | 627634 | 0 | 70300807 |
Lymphatic fistula | 11.18 | 10.15 | 23 | 627614 | 777 | 70300030 |
Spontaneous haemorrhage | 11.18 | 10.15 | 18 | 627619 | 501 | 70300306 |
Hypotension | 11.18 | 10.15 | 3864 | 623773 | 400517 | 69900290 |
Disability assessment scale score increased | 11.16 | 10.15 | 54 | 627583 | 2917 | 70297890 |
Anaemia of malignant disease | 11.15 | 10.15 | 22 | 627615 | 721 | 70300086 |
Base excess decreased | 11.14 | 10.15 | 15 | 627622 | 354 | 70300453 |
Retinal detachment | 11.13 | 10.15 | 38 | 627599 | 8429 | 70292378 |
Fibrin D dimer increased | 11.12 | 10.15 | 107 | 627530 | 7276 | 70293531 |
Hyperammonaemia | 11.10 | 10.15 | 50 | 627587 | 10243 | 70290564 |
Pulmonary interstitial emphysema syndrome | 11.09 | 10.15 | 17 | 627620 | 453 | 70300354 |
Hypochloraemia | 11.08 | 10.15 | 43 | 627594 | 2108 | 70298699 |
Arterial occlusive disease | 11.08 | 10.15 | 111 | 627526 | 7631 | 70293176 |
Transfusion | 11.07 | 10.15 | 231 | 627406 | 18605 | 70282202 |
Cardiovascular somatic symptom disorder | 11.06 | 10.15 | 6 | 627631 | 36 | 70300771 |
Femoral hernia incarcerated | 11.04 | 10.15 | 23 | 627614 | 784 | 70300023 |
Spontaneous haematoma | 11.03 | 10.15 | 31 | 627606 | 1283 | 70299524 |
Meningitis cryptococcal | 11.02 | 10.15 | 8 | 627629 | 3320 | 70297487 |
Heart rate | 10.97 | 10.15 | 7 | 627630 | 59 | 70300748 |
Nasal polyps | 10.95 | 10.15 | 73 | 627564 | 4443 | 70296364 |
Procalcitonin increased | 10.89 | 10.15 | 49 | 627588 | 2567 | 70298240 |
Cerebral haemorrhage | 10.88 | 10.15 | 582 | 627055 | 53282 | 70247525 |
Hypoxic-ischaemic encephalopathy | 10.88 | 10.15 | 31 | 627606 | 7277 | 70293530 |
Lung disorder | 10.87 | 10.15 | 734 | 626903 | 68750 | 70232057 |
Aortic arteriosclerosis | 10.86 | 10.15 | 112 | 627525 | 7757 | 70293050 |
Cell death | 10.86 | 10.15 | 69 | 627568 | 4131 | 70296676 |
Oesophageal variceal ligation | 10.85 | 10.15 | 9 | 627628 | 118 | 70300689 |
Uterine cancer | 10.84 | 10.15 | 9 | 627628 | 3490 | 70297317 |
Toxic neuropathy | 10.84 | 10.15 | 24 | 627613 | 854 | 70299953 |
Adverse event | 10.84 | 10.15 | 344 | 627293 | 49117 | 70251690 |
Asthenopia | 10.83 | 10.15 | 3 | 627634 | 2193 | 70298614 |
Biliary dyskinesia | 10.80 | 10.15 | 46 | 627591 | 2353 | 70298454 |
Multiple organ dysfunction syndrome | 10.79 | 10.15 | 820 | 626817 | 107695 | 70193112 |
Gait deviation | 10.78 | 10.15 | 7 | 627630 | 61 | 70300746 |
Vaccination site reaction | 10.73 | 10.15 | 9 | 627628 | 120 | 70300687 |
Deafness | 10.72 | 10.15 | 114 | 627523 | 19189 | 70281618 |
Soft tissue swelling | 10.69 | 10.15 | 29 | 627608 | 1175 | 70299632 |
Rash pruritic | 10.67 | 10.15 | 452 | 627185 | 62539 | 70238268 |
Hemiparesis | 10.67 | 10.15 | 359 | 627278 | 31110 | 70269697 |
Application site erythema | 10.64 | 10.15 | 16 | 627621 | 4745 | 70296062 |
Virologic failure | 10.63 | 10.15 | 11 | 627626 | 3839 | 70296968 |
Limb deformity | 10.63 | 10.15 | 9 | 627628 | 3456 | 70297351 |
Chronic actinic dermatitis | 10.62 | 10.15 | 5 | 627632 | 21 | 70300786 |
Product complaint | 10.61 | 10.15 | 64 | 627573 | 12167 | 70288640 |
Thoracic vertebral fracture | 10.60 | 10.15 | 76 | 627561 | 4738 | 70296069 |
Rheumatoid lung | 10.59 | 10.15 | 9 | 627628 | 3450 | 70297357 |
Heart rate decreased | 10.59 | 10.15 | 660 | 626977 | 61355 | 70239452 |
Gastric cancer | 10.58 | 10.15 | 42 | 627595 | 8913 | 70291894 |
Toothache | 10.58 | 10.15 | 108 | 627529 | 18322 | 70282485 |
Anaemia macrocytic | 10.56 | 10.15 | 80 | 627557 | 5075 | 70295732 |
Wound infection fungal | 10.55 | 10.15 | 11 | 627626 | 196 | 70300611 |
Bacteraemia | 10.55 | 10.15 | 189 | 627448 | 29120 | 70271687 |
Hyperparathyroidism | 10.47 | 10.15 | 54 | 627583 | 2993 | 70297814 |
Perineal cyst | 10.46 | 10.15 | 12 | 627625 | 239 | 70300568 |
Neutrophil function disorder | 10.44 | 10.15 | 5 | 627632 | 22 | 70300785 |
Parkinsonism | 10.44 | 10.15 | 86 | 627551 | 15239 | 70285568 |
Myeloblast percentage decreased | 10.43 | 10.15 | 6 | 627631 | 41 | 70300766 |
Craniocerebral injury | 10.41 | 10.15 | 73 | 627564 | 4518 | 70296289 |
Eye infection | 10.41 | 10.15 | 50 | 627587 | 10068 | 70290739 |
Adrenal cyst | 10.40 | 10.15 | 10 | 627627 | 161 | 70300646 |
Erythema multiforme | 10.38 | 10.15 | 95 | 627542 | 16469 | 70284338 |
Emotional distress | 10.37 | 10.15 | 250 | 627387 | 36938 | 70263869 |
Incision site haemorrhage | 10.34 | 10.15 | 26 | 627611 | 1006 | 70299801 |
Therapeutic reaction time decreased | 10.34 | 10.15 | 48 | 627589 | 2549 | 70298258 |
Focal dyscognitive seizures | 10.33 | 10.15 | 9 | 627628 | 3408 | 70297399 |
Histoplasmosis | 10.31 | 10.15 | 3 | 627634 | 2124 | 70298683 |
Cerebrovascular insufficiency | 10.31 | 10.15 | 9 | 627628 | 127 | 70300680 |
Accidental exposure to product by child | 10.31 | 10.15 | 6 | 627631 | 2800 | 70298007 |
Blood pressure diastolic decreased | 10.30 | 10.15 | 300 | 627337 | 25480 | 70275327 |
Injury associated with device | 10.29 | 10.15 | 7 | 627630 | 3005 | 70297802 |
Hepatic steatosis | 10.29 | 10.15 | 381 | 627256 | 33432 | 70267375 |
Foot deformity | 10.28 | 10.15 | 125 | 627512 | 20530 | 70280277 |
Gastrointestinal wall thickening | 10.27 | 10.15 | 45 | 627592 | 2331 | 70298476 |
Pulmonary sepsis | 10.27 | 10.15 | 57 | 627580 | 3250 | 70297557 |
Gastroenteritis salmonella | 10.26 | 10.15 | 25 | 627612 | 948 | 70299859 |
Renal atrophy | 10.25 | 10.15 | 36 | 627601 | 1681 | 70299126 |
Autoimmune nephritis | 10.24 | 10.15 | 19 | 627618 | 594 | 70300213 |
Chondrocalcinosis pyrophosphate | 10.22 | 10.15 | 37 | 627600 | 1754 | 70299053 |
Obsessive-compulsive disorder | 10.21 | 10.15 | 20 | 627617 | 5350 | 70295457 |
Abdominal wall cyst | 10.20 | 10.15 | 6 | 627631 | 43 | 70300764 |
Endoscopy upper gastrointestinal tract | 10.20 | 10.15 | 9 | 627628 | 129 | 70300678 |
Jejunostomy | 10.16 | 10.15 | 7 | 627630 | 68 | 70300739 |
Autoimmune encephalopathy | 10.15 | 10.15 | 8 | 627629 | 97 | 70300710 |
None
Source | Code | Description |
---|---|---|
ATC | A02BC02 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR ACID RELATED DISORDERS DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) Proton pump inhibitors |
ATC | A02BD04 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR ACID RELATED DISORDERS DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) Combinations for eradication of Helicobacter pylori |
ATC | A02BD11 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR ACID RELATED DISORDERS DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD) Combinations for eradication of Helicobacter pylori |
FDA MoA | N0000000147 | Proton Pump Inhibitors |
FDA EPC | N0000175525 | Proton Pump Inhibitor |
MeSH PA | D000897 | Anti-Ulcer Agents |
MeSH PA | D004791 | Enzyme Inhibitors |
MeSH PA | D005765 | Gastrointestinal Agents |
MeSH PA | D054328 | Proton Pump Inhibitors |
CHEBI has role | CHEBI:35703 | Xenobiotic |
CHEBI has role | CHEBI:49200 | proton pump inhibitors |
CHEBI has role | CHEBI:49201 | anti-ulcer drugs |
CHEBI has role | CHEBI:78298 | environmental contaminants |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Peptic ulcer | indication | 13200003 | DOID:750 |
Erosive esophagitis | indication | 40719004 | |
Zollinger-Ellison syndrome | indication | 53132006 | DOID:0050782 |
Multiple endocrine adenomas | indication | 60549007 | |
Gastroesophageal reflux disease | indication | 235595009 | DOID:8534 |
Maintenance of Healing Erosive Esophagitis | indication | ||
Gastric Hypersecretory Conditions | indication | ||
Upper gastrointestinal hemorrhage | off-label use | 37372002 | |
Duodenal ulcer disease | off-label use | 51868009 | DOID:1724 |
Gastric ulcer | off-label use | 397825006 | DOID:10808 |
Pathological Gastric Hypersecretory Condition | off-label use | ||
Duodenal Ulcer due to H. Pylori | off-label use | ||
Prevention of NSAID-Induced Gastric Ulcer | off-label use | ||
Osteoporosis | contraindication | 64859006 | DOID:11476 |
Pernicious anemia | contraindication | 84027009 | DOID:13381 |
Fracture of bone | contraindication | 125605004 | |
Hypomagnesemia | contraindication | 190855004 |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 9.42 | acidic |
pKa2 | 3.58 | Basic |
pKa3 | 2.32 | Basic |
Formulation strength | Trade name | Applicant | Application number | Approval date | Type | Dose form | Route | Patent number | Patent expiration date | Patent use |
---|---|---|---|---|---|---|---|---|---|---|
EQ 40MG BASE | PROTONIX | WYETH PHARMS | N022020 | Nov. 14, 2007 | RX | FOR SUSPENSION, DELAYED RELEASE | ORAL | 7550153 | Sept. 30, 2024 | EROSIVE ESOPHAGITIS, HYPERSECRETORY CONDITIONS INCLUDING ZOLLINGER-ELLISON SYNDROME, MAINTENANCE OF HEALING OF EROSIVE ESOPHAGITIS AND REDUCTION OF SYMPTOMS IN PATIENTS WITH GERD |
EQ 40MG BASE | PROTONIX | WYETH PHARMS | N022020 | Nov. 14, 2007 | RX | FOR SUSPENSION, DELAYED RELEASE | ORAL | 7553498 | Sept. 30, 2024 | EROSIVE ESOPHAGITIS, HYPERSECRETORY CONDITIONS INCLUDING ZOLLINGER-ELLISON SYNDROME, MAINTENANCE OF HEALING OF EROSIVE ESOPHAGITIS AND REDUCTION OF SYMPTOMS IN PATIENTS WITH GERD |
EQ 40MG BASE | PROTONIX | WYETH PHARMS | N022020 | Nov. 14, 2007 | RX | FOR SUSPENSION, DELAYED RELEASE | ORAL | 7838027 | Sept. 30, 2024 | EROSIVE ESOPHAGITIS, HYPERSECRETORY CONDITIONS INCLUDING ZOLLINGER-ELLISON SYNDROME, MAINTENANCE OF HEALING OF EROSIVE ESOPHAGITIS AND REDUCTION OF SYMPTOMS IN PATIENTS WITH GERD |
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Potassium-transporting ATPase | Transporter | INHIBITOR | CHEMBL | CHEMBL | |||||
Fatty acid synthase | Enzyme | Ki | 5.39 | CHEMBL | |||||
Solute carrier family 22 member 2 | Transporter | IC50 | 5.82 | CHEMBL | |||||
Multidrug and toxin extrusion protein 1 | Transporter | IC50 | 5.55 | CHEMBL | |||||
Multidrug and toxin extrusion protein 2 | Transporter | IC50 | 4.36 | CHEMBL | |||||
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 | Enzyme | IC50 | 4.20 | CHEMBL | |||||
Sodium/potassium-transporting ATPase subunit alpha-1 | Transporter | WOMBAT-PK | |||||||
Indoleamine 2,3-dioxygenase 2 | Enzyme | IC50 | 4.90 | CHEMBL | |||||
Potassium-transporting ATPase | Enzyme | IC50 | 6 | SCIENTIFIC LITERATURE |
ID | Source |
---|---|
4021208 | VUID |
N0000148654 | NUI |
D02593 | KEGG_DRUG |
164579-32-2 | SECONDARY_CAS_RN |
4021208 | VANDF |
4021209 | VANDF |
C0081876 | UMLSCUI |
CHEBI:7915 | CHEBI |
CHEMBL1502 | ChEMBL_ID |
DB00213 | DRUGBANK_ID |
CHEMBL3989559 | ChEMBL_ID |
CHEMBL1200408 | ChEMBL_ID |
D000077402 | MESH_DESCRIPTOR_UI |
4679 | PUBCHEM_CID |
7260 | IUPHAR_LIGAND_ID |
6548 | INN_ID |
D8TST4O562 | UNII |
236632 | RXNORM |
130104 | MMSL |
8654 | MMSL |
d04514 | MMSL |
006006 | NDDF |
006493 | NDDF |
009120 | NDDF |
116510001 | SNOMEDCT_US |
317317009 | SNOMEDCT_US |
395821003 | SNOMEDCT_US |
432408008 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Protonix Delayed-Release | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0008-0841 | TABLET, DELAYED RELEASE | 40 mg | ORAL | NDA | 30 sections |
Protonix Delayed-Release | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0008-0841 | TABLET, DELAYED RELEASE | 40 mg | ORAL | NDA | 30 sections |
Protonix Delayed-Release | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0008-0843 | TABLET, DELAYED RELEASE | 20 mg | ORAL | NDA | 30 sections |
Protonix Delayed-Release | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0008-0843 | TABLET, DELAYED RELEASE | 20 mg | ORAL | NDA | 30 sections |
Protonix Delayed-Release | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0008-0844 | GRANULE, DELAYED RELEASE | 40 mg | ORAL | NDA | 30 sections |
Protonix Delayed-Release | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0008-0844 | GRANULE, DELAYED RELEASE | 40 mg | ORAL | NDA | 30 sections |
Protonix I.V. | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0008-0923 | INJECTION, POWDER, FOR SOLUTION | 40 mg | INTRAVENOUS | NDA | 28 sections |
Protonix I.V. | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0008-0923 | INJECTION, POWDER, FOR SOLUTION | 40 mg | INTRAVENOUS | NDA | 28 sections |
Protonix I.V. | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0008-2001 | INJECTION, POWDER, FOR SOLUTION | 40 mg | INTRAVENOUS | NDA | 27 sections |
Protonix I.V. | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0008-2001 | INJECTION, POWDER, FOR SOLUTION | 40 mg | INTRAVENOUS | NDA | 27 sections |
Protonix I.V. | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0008-4001 | INJECTION, POWDER, FOR SOLUTION | 40 mg | INTRAVENOUS | NDA | 28 sections |
Protonix I.V. | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0008-4001 | INJECTION, POWDER, FOR SOLUTION | 40 mg | INTRAVENOUS | NDA | 28 sections |
Pantoprazole Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9284 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 40 mg | INTRAVENOUS | NDA | 26 sections |
Pantoprazole Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9284 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 40 mg | INTRAVENOUS | NDA | 26 sections |
Pantoprazole Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9300 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 40 mg | INTRAVENOUS | NDA | 26 sections |
Pantoprazole Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0143-9300 | INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION | 40 mg | INTRAVENOUS | NDA | 26 sections |
Pantoprazole Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-6688 | TABLET, DELAYED RELEASE | 20 mg | ORAL | ANDA | 28 sections |
Pantoprazole Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-6688 | TABLET, DELAYED RELEASE | 20 mg | ORAL | ANDA | 28 sections |
Pantoprazole Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-6689 | TABLET, DELAYED RELEASE | 40 mg | ORAL | ANDA | 28 sections |
Pantoprazole Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0378-6689 | TABLET, DELAYED RELEASE | 40 mg | ORAL | ANDA | 28 sections |
Pantoprazole Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0480-4111 | INJECTION, POWDER, FOR SOLUTION | 40 mg | INTRAVENOUS | ANDA | 28 sections |
Pantoprazole Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-7629 | TABLET, DELAYED RELEASE | 40 mg | ORAL | ANDA | 28 sections |
Pantoprazole Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8113 | TABLET, DELAYED RELEASE | 20 mg | ORAL | ANDA | 27 sections |
Pantoprazole Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8113 | TABLET, DELAYED RELEASE | 20 mg | ORAL | ANDA | 27 sections |
Pantoprazole Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8308 | TABLET, DELAYED RELEASE | 40 mg | ORAL | ANDA | 29 sections |
Pantoprazole Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0615-8308 | TABLET, DELAYED RELEASE | 40 mg | ORAL | ANDA | 29 sections |
Pantoprazole Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0781-3232 | INJECTION, POWDER, FOR SOLUTION | 40 mg | INTRAVENOUS | ANDA | 28 sections |
Pantoprazole Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0781-3232 | INJECTION, POWDER, FOR SOLUTION | 40 mg | INTRAVENOUS | ANDA | 28 sections |
Pantoprazole Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-6474 | TABLET, DELAYED RELEASE | 40 mg | ORAL | ANDA | 27 sections |
Pantoprazole Sodium | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-6474 | TABLET, DELAYED RELEASE | 40 mg | ORAL | ANDA | 27 sections |