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pamabrom 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| 2047 | 10381-75-6 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
None
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
None
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Ocular hypertension | contraindication | 4210003 | DOID:9282 |
| Alcoholism | contraindication | 7200002 | |
| Peptic ulcer | contraindication | 13200003 | DOID:750 |
| Hyperthyroidism | contraindication | 34486009 | DOID:7998 |
| Hypertensive disorder | contraindication | 38341003 | DOID:10763 |
| Hepatic failure | contraindication | 59927004 | |
| Blood coagulation disorder | contraindication | 64779008 | DOID:1247 |
| Poisoning by acetaminophen | contraindication | 70273001 | |
| Chronic idiopathic constipation | contraindication | 82934008 | |
| Disease of liver | contraindication | 235856003 | DOID:409 |
| Bladder outflow obstruction | contraindication | 236645006 | |
| Benign prostatic hyperplasia | contraindication | 266569009 | |
| Retention of urine | contraindication | 267064002 | |
| Angle-closure glaucoma | contraindication | 392291006 | DOID:13550 |
| Vitamin K Deficiency Induced Hypoprothrombinemia | contraindication |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 6.87 | acidic |
| pKa2 | 2.43 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Adenosine receptor A1 | GPCR | Ki | 4.99 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| 4019460 | VUID |
| N0000179338 | NUI |
| D08962 | KEGG_DRUG |
| 4019460 | VANDF |
| C0135166 | UMLSCUI |
| CHEBI:748386 | CHEBI |
| CHEMBL316160 | ChEMBL_ID |
| CHEMBL2104825 | ChEMBL_ID |
| C069987 | MESH_SUPPLEMENTAL_RECORD_UI |
| 11806 | PUBCHEM_CID |
| UA8U0KJM72 | UNII |
| DB14018 | DRUGBANK_ID |
| 1546386 | RXNORM |
| 5225 | MMSL |
| d03585 | MMSL |
| 002318 | NDDF |
| 116552006 | SNOMEDCT_US |
| 398981003 | SNOMEDCT_US |
| 606-04-2 | SECONDARY_CAS_RN |
Pharmaceutical products:
| Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
|---|---|---|---|---|---|---|---|---|
| Midol Bloat Relief | HUMAN OTC DRUG LABEL | 1 | 0280-0070 | TABLET | 50 mg | ORAL | OTC Monograph Drug | 12 sections |
| Midol Complete Caffeine Free | HUMAN OTC DRUG LABEL | 3 | 0280-0078 | TABLET | 25 mg | ORAL | OTC Monograph Drug | 17 sections |
| Pamabrom | HUMAN OTC DRUG LABEL | 1 | 0363-0795 | CAPSULE, LIQUID FILLED | 50 mg | ORAL | unapproved drug other | 8 sections |
| Menstrual Relief | HUMAN OTC DRUG LABEL | 3 | 11673-967 | TABLET, FILM COATED | 25 mg | ORAL | OTC Monograph Drug | 16 sections |
| menstrual pain reliefmaximum strength | HUMAN OTC DRUG LABEL | 3 | 11822-6790 | TABLET, FILM COATED | 25 mg | ORAL | OTC Monograph Drug | 16 sections |
| Pamabrom | HUMAN OTC DRUG LABEL | 1 | 35916-1654 | CAPSULE, LIQUID FILLED | 50 mg | ORAL | OTC Monograph Drug | 11 sections |
| Menstrual ReliefMaximum Strength | HUMAN OTC DRUG LABEL | 3 | 36800-979 | TABLET, FILM COATED | 25 mg | ORAL | OTC Monograph Drug | 16 sections |
| Green Guard Cramp Relief | HUMAN OTC DRUG LABEL | 3 | 47682-049 | TABLET, FILM COATED | 25 mg | ORAL | OTC Monograph Drug | 17 sections |
| Medi First Plus PMS Relief | HUMAN OTC DRUG LABEL | 3 | 47682-723 | TABLET, COATED | 25 mg | ORAL | OTC Monograph Drug | 17 sections |
| Medi First PMS Relief | HUMAN OTC DRUG LABEL | 3 | 47682-823 | TABLET, COATED | 25 mg | ORAL | OTC Monograph Drug | 17 sections |
| Unishield Cramp | HUMAN OTC DRUG LABEL | 2 | 49314-8103 | TABLET, FILM COATED | 25 mg | ORAL | OTC monograph not final | 17 sections |
| Unishield PMS Relief | HUMAN OTC DRUG LABEL | 3 | 49314-8238 | TABLET, FILM COATED | 25 mg | ORAL | OTC Monograph Drug | 17 sections |
| FEM-PRIN | HUMAN OTC DRUG LABEL | 3 | 50332-0145 | TABLET, FILM COATED | 25 mg | ORAL | OTC Monograph Drug | 16 sections |
| Menstrual ReliefMaximum Strength | HUMAN OTC DRUG LABEL | 3 | 50844-679 | TABLET, FILM COATED | 25 mg | ORAL | OTC Monograph Drug | 16 sections |
| Multi-Symptom PMS Relief | HUMAN OTC DRUG LABEL | 3 | 51316-679 | TABLET, FILM COATED | 25 mg | ORAL | OTC Monograph Drug | 16 sections |
| Femadrine | HUMAN OTC DRUG LABEL | 2 | 51532-0700 | TABLET | 25 1 | ORAL | OTC monograph not final | 11 sections |
| BackAidMax | HUMAN OTC DRUG LABEL | 2 | 52389-153 | TABLET, FILM COATED | 25 mg | ORAL | OTC Monograph Drug | 15 sections |
| DiurexMax | HUMAN OTC DRUG LABEL | 1 | 52389-249 | TABLET, FILM COATED | 50 mg | ORAL | OTC Monograph Drug | 13 sections |
| DiurexMax | HUMAN OTC DRUG LABEL | 1 | 52389-349 | TABLET, FILM COATED | 50 mg | ORAL | Export only | |
| Menstrual ReliefMaximum Strength | HUMAN OTC DRUG LABEL | 3 | 55301-679 | TABLET, FILM COATED | 25 mg | ORAL | OTC Monograph Drug | 16 sections |
| Menstrual ReliefMaximum Strength | HUMAN OTC DRUG LABEL | 3 | 55319-979 | TABLET, FILM COATED | 25 mg | ORAL | OTC Monograph Drug | 16 sections |
| Menstrual Pain ReliefMaximum Strength / Multi Symptom | HUMAN OTC DRUG LABEL | 3 | 55910-967 | TABLET, FILM COATED | 25 mg | ORAL | OTC Monograph Drug | 16 sections |
| PMS ReliefMaximum Strength | HUMAN OTC DRUG LABEL | 3 | 59779-879 | TABLET, FILM COATED | 25 mg | ORAL | OTC Monograph Drug | 16 sections |
| Cramp Tabs | HUMAN OTC DRUG LABEL | 2 | 67060-700 | TABLET | 25 1 | ORAL | OTC monograph not final | 9 sections |
| Menstrual ReliefMaximum Strength Multi Symptom | HUMAN OTC DRUG LABEL | 3 | 70000-0145 | TABLET, FILM COATED | 25 mg | ORAL | OTC Monograph Drug | 16 sections |
| RIGHT REMEDIES Maximum Strength Diuretic | HUMAN OTC DRUG LABEL | 1 | 70692-595 | CAPSULE, LIQUID FILLED | 50 mg | ORAL | OTC Monograph Drug | 11 sections |
| Pamprin Multi-Symptom Maximum Strength | HUMAN OTC DRUG LABEL | 3 | 71687-3003 | TABLET | 25 mg | ORAL | OTC Monograph Drug | 17 sections |
| PamprinBloat | HUMAN OTC DRUG LABEL | 1 | 71687-3009 | TABLET, FILM COATED | 50 mg | ORAL | OTC Monograph Drug | 9 sections |
| Premsyn pms Premenstrual Pain Relief | HUMAN OTC DRUG LABEL | 3 | 71687-3102 | TABLET | 25 mg | ORAL | OTC Monograph Drug | 13 sections |
| Thompson Cramp Relief | HUMAN OTC DRUG LABEL | 3 | 73408-923 | TABLET, FILM COATED | 25 mg | ORAL | OTC Monograph Drug | 17 sections |