oxitropium 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
atropine derivatives 2022 99571-64-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • oxitropium iodide
  • oxytropium bromide
  • oxitropium
  • oxitropium bromide
  • Molecular weight: 332.42
  • Formula: C19H26NO4
  • CLOGP: -2.15
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 1
  • TPSA: 59.06
  • ALOGS: -4.76
  • ROTB: 6

Drug dosage:

DoseUnitRoute
0.60 mg Inhal.aerosol
4 mg Inhal.solution

ADMET properties:

PropertyValueReference
BA (Bioavailability) 1 % Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC R03BB02 RESPIRATORY SYSTEM
DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
Anticholinergics
MeSH PA D010276 Parasympatholytics
MeSH PA D018373 Peripheral Nervous System Agents

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Chronic obstructive lung disease indication 13645005 DOID:3083




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 13.24 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01946 KEGG_DRUG
30286-75-0 SECONDARY_CAS_RN
C0069776 UMLSCUI
CHEBI:135418 CHEBI
CHEMBL4297364 ChEMBL_ID
CHEMBL1739767 ChEMBL_ID
DB12086 DRUGBANK_ID
C017590 MESH_SUPPLEMENTAL_RECORD_UI
6917866 PUBCHEM_CID
8G15T83E6I UNII
32649 RXNORM
004014 NDDF
006120 NDDF
349953003 SNOMEDCT_US
395816001 SNOMEDCT_US
395993006 SNOMEDCT_US
CHEMBL4297109 ChEMBL_ID
CHEMBL1697846 ChEMBL_ID
3955 INN_ID

Pharmaceutical products:

None