ampicillin ๐Ÿถ Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antibiotics, 6-aminopenicillanic acid derivatives 198 69-53-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • ampicillin hydrate
  • ampicillin
  • ampicillin sodium
  • ampicillin trihydrate
  • ampicillin anhydrous
Semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
  • Molecular weight: 349.41
  • Formula: C16H19N3O4S
  • CLOGP: -1.20
  • LIPINSKI: 0
  • HAC: 7
  • HDO: 3
  • TPSA: 112.73
  • ALOGS: -2.76
  • ROTB: 4

  • Status: OFP

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

DoseUnitRoute
2 g O
6 g P
2 g R
6 g P

ADMET properties:

PropertyValueReference
BDDCS (Biopharmaceutical Drug Disposition Classification System) 3 Benet LZ, Broccatelli F, Oprea TI
S (Water solubility) 50 mg/mL Bocci G, Oprea TI, Benet LZ
EoM (Fraction excreted unchanged in urine) 88 % Benet LZ, Broccatelli F, Oprea TI
MRTD (Maximum Recommended Therapeutic Daily Dose) 166.85 ยตM/kg/day Contrera JF, Matthews EJ, Kruhlak NL, Benz RD
BA (Bioavailability) 62 % Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H
Vd (Volume of distribution) 0.22 L/kg Lombardo F, Berellini G, Obach RS
CL (Clearance) 2.80 mL/min/kg Lombardo F, Berellini G, Obach RS
fu (Fraction unbound in plasma) 0.85 % Lombardo F, Berellini G, Obach RS
t_half (Half-life) 1.40 hours Lombardo F, Berellini G, Obach RS

Approvals:

DateAgencyCompanyOrphan
Dec. 17, 1965 FDA WYETH AYERST

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Premature delivery 697.12 16.35 248 11642 30033 63447099
Normal labour 437.61 16.35 77 11813 440 63476692
Maternal exposure during pregnancy 416.09 16.35 337 11553 219725 63257407
Delivery 378.02 16.35 80 11810 1323 63475809
Drug hypersensitivity 323.57 16.35 341 11549 310346 63166786
Type IV hypersensitivity reaction 266.06 16.35 69 11821 2829 63474303
Cross sensitivity reaction 230.49 16.35 58 11832 2104 63475028
Premature baby 203.40 16.35 92 11798 20643 63456489
Foetal exposure during pregnancy 187.94 16.35 100 11790 31862 63445270
Exposure during pregnancy 154.55 16.35 167 11723 155380 63321752
Low birth weight baby 128.97 16.35 49 11841 7080 63470052
Rash maculo-papular 113.39 16.35 72 11818 31824 63445308
Product use in unapproved indication 92.64 16.35 139 11751 178941 63298191
Pathogen resistance 91.17 16.35 37 11853 6361 63470771
Drug reaction with eosinophilia and systemic symptoms 74.66 16.35 57 11833 33779 63443353
Enterocolitis haemorrhagic 70.37 16.35 21 11869 1445 63475687
Toxic epidermal necrolysis 67.91 16.35 48 11842 25286 63451846
Amniotic cavity infection 60.23 16.35 18 11872 1245 63475887
Respiratory acidosis 57.09 16.35 27 11863 6688 63470444
Multiple organ dysfunction syndrome 56.32 16.35 61 11829 56691 63420441
Premature rupture of membranes 51.62 16.35 23 11867 4970 63472162
Septic shock 51.59 16.35 63 11827 66566 63410566
Intraventricular haemorrhage 51.06 16.35 18 11872 2102 63475030
Jarisch-Herxheimer reaction 49.70 16.35 12 11878 365 63476767
Caesarean section 49.69 16.35 34 11856 16998 63460134
Neonatal disorder 49.25 16.35 13 11877 570 63476562
Stillbirth 47.93 16.35 24 11866 6726 63470406
Premature labour 46.35 16.35 29 11861 12475 63464657
Patent ductus arteriosus 45.29 16.35 20 11870 4230 63472902
Systemic candida 43.61 16.35 18 11872 3227 63473905
Appetite disorder 43.25 16.35 23 11867 7298 63469834
Oedema 42.37 16.35 70 11820 97552 63379580
Umbilical erythema 42.26 16.35 8 11882 72 63477060
Thymus disorder 41.85 16.35 10 11880 291 63476841
Enterococcal infection 41.75 16.35 23 11867 7825 63469307
Intraventricular haemorrhage neonatal 41.27 16.35 9 11881 172 63476960
Neonatal respiratory distress syndrome 39.13 16.35 16 11874 2802 63474330
Candida infection 38.25 16.35 36 11854 28315 63448817
Pseudomembranous colitis 37.59 16.35 16 11874 3096 63474036
Sepsis neonatal 37.29 16.35 10 11880 466 63476666
Laryngeal stenosis 37.23 16.35 12 11878 1066 63476066
Neonatal respiratory failure 36.96 16.35 9 11881 284 63476848
Long QT syndrome congenital 34.15 16.35 7 11883 98 63477034
Hepatic infarction 33.77 16.35 10 11880 670 63476462
Alopecia 33.09 16.35 11 11879 337525 63139607
Pulmonary haemorrhage 32.67 16.35 19 11871 7162 63469970
Perinatal stroke 32.43 16.35 5 11885 10 63477122
Clostridial infection 32.32 16.35 16 11874 4376 63472756
Liver abscess 32.26 16.35 14 11876 2840 63474292
Anaphylactic reaction 32.24 16.35 50 11840 66050 63411082
Klebsiella infection 32.08 16.35 20 11870 8546 63468586
Acute respiratory distress syndrome 31.97 16.35 30 11860 23504 63453628
Death neonatal 30.22 16.35 10 11880 965 63476167
Arthralgia 29.66 16.35 38 11852 569672 62907460
Guillain-Barre syndrome 28.11 16.35 14 11876 3879 63473253
Premature separation of placenta 27.33 16.35 11 11879 1850 63475282
Maternal drugs affecting foetus 26.89 16.35 15 11875 5227 63471905
Culture stool positive 26.79 16.35 7 11883 295 63476837
Joint swelling 26.77 16.35 14 11876 327652 63149480
Monocytosis 26.76 16.35 8 11882 554 63476578
Ventricular septal defect 26.55 16.35 14 11876 4364 63472768
Bradycardia neonatal 26.48 16.35 9 11881 943 63476189
Hydrops foetalis 26.13 16.35 8 11882 600 63476532
Neonatal infection 26.10 16.35 6 11884 147 63476985
Ventricular dysfunction 25.98 16.35 12 11878 2816 63474316
Fatigue 25.92 16.35 83 11807 887945 62589187
Foetal heart rate decreased 25.87 16.35 6 11884 153 63476979
Clostridium difficile colitis 25.63 16.35 25 11865 20544 63456588
Hepatic function abnormal 25.36 16.35 33 11857 37109 63440023
Polyhydramnios 25.21 16.35 11 11879 2260 63474872
Dysphoria 24.90 16.35 14 11876 4952 63472180
Hydrocephalus 24.05 16.35 14 11876 5286 63471846
Arthritis infective 23.94 16.35 15 11875 6463 63470669
Systemic lupus erythematosus 23.89 16.35 5 11885 208913 63268219
Peripheral swelling 23.82 16.35 10 11880 265932 63211200
Haemorrhagic diathesis 23.65 16.35 13 11877 4402 63472730
Hypotonia 23.51 16.35 17 11873 9268 63467864
Malaise 23.48 16.35 26 11864 415928 63061204
Bradypnoea 23.39 16.35 12 11878 3538 63473594
Glossodynia 23.30 16.35 3 11887 178873 63298259
Atelectasis neonatal 23.17 16.35 4 11886 20 63477112
Selective eating disorder 22.88 16.35 10 11880 2062 63475070
Generalised anxiety disorder 22.88 16.35 10 11880 2064 63475068
Thrombocytopenia neonatal 22.85 16.35 4 11886 22 63477110
Escherichia infection 22.80 16.35 19 11871 12735 63464397
Maternal exposure during delivery 22.49 16.35 9 11881 1491 63475641
Immune reconstitution inflammatory syndrome 22.27 16.35 14 11876 6070 63471062
Abdominal discomfort 21.71 16.35 17 11873 320868 63156264
Disseminated intravascular coagulation 21.60 16.35 22 11868 19029 63458103
Endocarditis candida 20.66 16.35 4 11886 41 63477091
Atrial septal defect 20.59 16.35 14 11876 6924 63470208
Hypotonia neonatal 20.51 16.35 8 11882 1238 63475894
Normal newborn 20.50 16.35 15 11875 8326 63468806
Neonatal respiratory distress 20.45 16.35 6 11884 389 63476743
Stevens-Johnson syndrome 19.96 16.35 24 11866 24926 63452206
Stenotrophomonas infection 19.88 16.35 9 11881 2018 63475114
Preterm premature rupture of membranes 19.56 16.35 8 11882 1401 63475731
Pain in extremity 19.50 16.35 20 11870 331466 63145666
Umbilical cord around neck 19.48 16.35 5 11885 196 63476936
Oliguria 19.33 16.35 15 11875 9086 63468046
Necrotising enterocolitis neonatal 19.15 16.35 5 11885 210 63476922
Enterobacter infection 19.07 16.35 9 11881 2218 63474914
Circulatory collapse 19.04 16.35 22 11868 21916 63455216
Pain 19.03 16.35 73 11817 740555 62736577
Apnoea 18.76 16.35 14 11876 8008 63469124
Treatment failure 18.61 16.35 7 11883 199036 63278096
Headache 18.55 16.35 59 11831 633182 62843950
Infantile apnoea 18.32 16.35 7 11883 1026 63476106
Congenital lymphoedema 17.92 16.35 3 11887 12 63477120
Exposure to SARS-CoV-2 17.89 16.35 8 11882 1743 63475389
Insomnia 17.86 16.35 9 11881 215243 63261889
Live birth 17.85 16.35 23 11867 25607 63451525
Cervical incompetence 17.82 16.35 6 11884 611 63476521
Nasopharyngitis 17.79 16.35 13 11877 254244 63222888
Hepatomegaly 17.79 16.35 16 11874 11873 63465259
Sepsis 17.75 16.35 66 11824 153057 63324075
Neuromuscular blockade 17.53 16.35 5 11885 293 63476839
Meconium in amniotic fluid 17.52 16.35 5 11885 294 63476838
Neonatal cardiac failure 17.38 16.35 3 11887 15 63477117
Megacolon 17.20 16.35 8 11882 1907 63475225
Oligohydramnios 16.91 16.35 12 11878 6354 63470778
Foetal death 16.87 16.35 15 11875 10965 63466167
Retained placenta or membranes 16.81 16.35 5 11885 340 63476792
Acute generalised exanthematous pustulosis 16.73 16.35 15 11875 11084 63466048
Drug resistance 16.64 16.35 21 11869 22912 63454220
Sinusitis 16.64 16.35 11 11879 226642 63250490
Perineal necrosis 16.53 16.35 4 11886 123 63477009
Sweat test abnormal 16.52 16.35 3 11887 21 63477111
Renal failure 16.48 16.35 54 11836 117598 63359534
Rheumatoid arthritis 16.47 16.35 14 11876 253805 63223327
Urine output decreased 16.42 16.35 15 11875 11355 63465777

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Premature baby 185.27 16.07 94 9006 19539 34928292
Foetal exposure during pregnancy 134.53 16.07 97 9003 38004 34909827
Low birth weight baby 92.91 16.07 44 9056 7861 34939970
Sepsis neonatal 87.07 16.07 19 9081 257 34947574
Neonatal disorder 75.35 16.07 21 9079 809 34947022
Drug hypersensitivity 68.31 16.07 94 9006 80435 34867396
Red blood cell hyperchromic morphology 65.62 16.07 10 9090 10 34947821
Type IV hypersensitivity reaction 56.06 16.07 19 9081 1415 34946416
Cardiac septal defect 52.79 16.07 13 9087 306 34947525
Pleocytosis 50.26 16.07 14 9086 538 34947293
Neonatal respiratory distress syndrome 49.07 16.07 23 9077 4011 34943820
Fatigue 45.34 16.07 20 9080 370633 34577198
Pulmonary haemorrhage 45.16 16.07 30 9070 10274 34937557
Pathogen resistance 44.96 16.07 29 9071 9453 34938378
Kidney duplex 44.84 16.07 12 9088 396 34947435
Intraventricular haemorrhage 42.54 16.07 20 9080 3511 34944320
Anisocytosis 38.64 16.07 11 9089 458 34947373
Intraventricular haemorrhage neonatal 38.19 16.07 10 9090 303 34947528
Drug ineffective 38.04 16.07 225 8875 456526 34491305
Necrotising colitis 37.04 16.07 13 9087 1075 34946756
Neonatal respiratory failure 36.58 16.07 10 9090 358 34947473
Drug resistance 36.22 16.07 39 9061 25888 34921943
Congenital cystic lung 36.03 16.07 9 9091 225 34947606
Systemic candida 35.56 16.07 18 9082 3708 34944123
Brain abscess 35.50 16.07 17 9083 3108 34944723
Patent ductus arteriosus 34.36 16.07 17 9083 3337 34944494
Pyrexia 34.34 16.07 174 8926 332839 34614992
Death 34.31 16.07 32 9068 398017 34549814
Listeriosis 33.80 16.07 12 9088 1026 34946805
Meningitis aseptic 32.02 16.07 16 9084 3208 34944623
Leukocytosis 31.53 16.07 35 9065 24030 34923801
Macrocytosis 30.51 16.07 11 9089 983 34946848
Cross sensitivity reaction 30.33 16.07 12 9088 1385 34946446
Nutritional condition abnormal 30.30 16.07 9 9091 436 34947395
Drug withdrawal syndrome neonatal 30.27 16.07 16 9084 3603 34944228
Janeway lesion 29.10 16.07 5 9095 16 34947815
Candida infection 28.97 16.07 29 9071 17686 34930145
Nocardiosis 28.95 16.07 16 9084 3935 34943896
Congenital skin dimples 28.25 16.07 7 9093 169 34947662
Hydrops foetalis 28.14 16.07 10 9090 857 34946974
Death neonatal 27.63 16.07 8 9092 354 34947477
Type I hypersensitivity 27.33 16.07 11 9089 1328 34946503
Drug reaction with eosinophilia and systemic symptoms 27.13 16.07 38 9062 32974 34914857
Bradycardia neonatal 26.99 16.07 10 9090 966 34946865
Enterocolitis haemorrhagic 26.92 16.07 10 9090 973 34946858
Polyhydramnios 25.95 16.07 7 9093 238 34947593
Apnoea 25.86 16.07 18 9082 6646 34941185
Klebsiella infection 24.02 16.07 19 9081 8512 34939319
Rash maculo-papular 23.75 16.07 33 9067 28418 34919413
Acute generalised exanthematous pustulosis 23.29 16.07 17 9083 6759 34941072
Neonatal candida infection 23.23 16.07 4 9096 13 34947818
Fall 23.12 16.07 12 9088 202873 34744958
Fungal skin infection 23.04 16.07 12 9088 2622 34945209
Eosinophilia 22.77 16.07 31 9069 26191 34921640
Respiratory failure 22.76 16.07 71 9029 108501 34839330
Strongyloidiasis 22.71 16.07 12 9088 2699 34945132
Respiratory distress 22.11 16.07 36 9064 35629 34912202
Pseudo-Bartter syndrome 21.69 16.07 4 9096 21 34947810
Pulmonary physical examination abnormal 21.24 16.07 4 9096 24 34947807
Exposure during pregnancy 21.17 16.07 18 9082 8916 34938915
Disseminated intravascular coagulation 20.80 16.07 27 9073 21789 34926042
Lymphocytosis 20.45 16.07 11 9089 2566 34945265
Posthaemorrhagic hydrocephalus 20.17 16.07 5 9095 121 34947710
Atrial septal defect 19.82 16.07 16 9084 7376 34940455
Bronchopulmonary dysplasia 19.80 16.07 7 9093 591 34947240
Aspartate aminotransferase increased 19.78 16.07 50 9050 67733 34880098
Grey syndrome neonatal 19.68 16.07 3 9097 3 34947828
Congenital syphilis 19.68 16.07 3 9097 3 34947828
Endocarditis 19.41 16.07 15 9085 6496 34941335
Rash 18.57 16.07 110 8990 222642 34725189
Enterococcal infection 18.56 16.07 17 9083 9289 34938542
Maternal drugs affecting foetus 18.48 16.07 12 9088 3953 34943878
Trichosporon infection 18.40 16.07 7 9093 727 34947104
Neonatal hypoxia 18.33 16.07 6 9094 401 34947430
Hepatotoxicity 18.05 16.07 25 9075 21460 34926371
Dry gangrene 17.88 16.07 6 9094 433 34947398
Sepsis 17.76 16.07 88 9012 166473 34781358
Hepatic function abnormal 17.67 16.07 37 9063 44326 34903505
Candida pneumonia 17.54 16.07 6 9094 459 34947372
Dizziness 17.13 16.07 19 9081 218502 34729329
Apgar score low 17.05 16.07 7 9093 888 34946943
Tubulointerstitial nephritis 16.97 16.07 24 9076 21000 34926831
Pleural effusion 16.78 16.07 53 9047 81493 34866338
Photophobia 16.44 16.07 14 9086 6950 34940881
Mucormycosis 16.23 16.07 13 9087 5929 34941902
Pseudomonas infection 16.20 16.07 18 9082 12364 34935467
Microtia 16.13 16.07 5 9095 280 34947551

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Type IV hypersensitivity reaction 337.81 14.09 89 14451 3992 79725856
Cross sensitivity reaction 255.56 14.09 70 14470 3642 79726206
Drug hypersensitivity 223.03 14.09 273 14267 298643 79431205
Premature delivery 167.60 14.09 83 14457 23384 79706464
Exposure during pregnancy 166.84 14.09 142 14398 100990 79628858
Rash maculo-papular 143.13 14.09 102 14438 55976 79673872
Maternal exposure during pregnancy 125.40 14.09 139 14401 136399 79593449
Pathogen resistance 118.30 14.09 56 14484 14286 79715562
Drug reaction with eosinophilia and systemic symptoms 109.55 14.09 92 14448 64152 79665696
Enterocolitis haemorrhagic 95.65 14.09 29 14511 2165 79727683
Toxic epidermal necrolysis 64.19 14.09 58 14482 44523 79685325
Amniotic cavity infection 63.49 14.09 17 14523 810 79729038
Enterococcal infection 63.26 14.09 38 14502 15622 79714226
Drug ineffective 56.14 14.09 362 14178 1080551 78649297
Anaphylactic reaction 55.04 14.09 72 14468 83671 79646177
Septic shock 50.92 14.09 85 14455 122716 79607132
Pyrexia 50.10 14.09 250 14290 678459 79051389
Pleocytosis 45.96 14.09 15 14525 1424 79728424
Klebsiella infection 45.70 14.09 31 14509 15689 79714159
Oedema 44.62 14.09 79 14461 119501 79610347
Premature labour 43.62 14.09 24 14516 8366 79721482
Premature rupture of membranes 43.37 14.09 19 14521 4050 79725798
Thymus disorder 42.24 14.09 10 14530 287 79729561
Respiratory acidosis 42.21 14.09 26 14514 11174 79718674
Caesarean section 41.98 14.09 27 14513 12508 79717340
Pseudomembranous colitis 41.31 14.09 20 14520 5354 79724494
Appetite disorder 39.85 14.09 22 14518 7717 79722131
Listeriosis 39.40 14.09 15 14525 2235 79727613
Hepatic function abnormal 39.22 14.09 57 14483 73050 79656798
Arthritis infective 38.49 14.09 22 14518 8249 79721599
Fatigue 37.95 14.09 70 14470 929657 78800191
Laryngeal stenosis 37.43 14.09 12 14528 1076 79728772
Candida infection 36.91 14.09 40 14500 38174 79691674
Tubulointerstitial nephritis 36.89 14.09 40 14500 38195 79691653
Multiple organ dysfunction syndrome 36.82 14.09 73 14467 120173 79609675
Meningitis aseptic 36.52 14.09 20 14520 6908 79722940
Jarisch-Herxheimer reaction 34.76 14.09 11 14529 946 79728902
Clostridial infection 34.34 14.09 18 14522 5696 79724152
Brain abscess 33.87 14.09 17 14523 4919 79724929
Pseudomonas infection 33.68 14.09 29 14511 20874 79708974
Clostridium difficile colitis 33.31 14.09 35 14505 32248 79697600
Drug resistance 32.02 14.09 39 14501 42174 79687674
Nocardiosis 31.62 14.09 17 14523 5662 79724186
Long QT syndrome congenital 31.53 14.09 7 14533 150 79729698
Rash 31.23 14.09 196 14344 578162 79151686
Hepatic infarction 31.10 14.09 10 14530 905 79728943
Janeway lesion 30.88 14.09 5 14535 16 79729832
Drug eruption 30.77 14.09 39 14501 43896 79685952
Culture stool positive 30.50 14.09 9 14531 612 79729236
Acute generalised exanthematous pustulosis 29.98 14.09 25 14515 17229 79712619
Type I hypersensitivity 29.74 14.09 15 14525 4383 79725465
Leukocytosis 29.53 14.09 38 14502 43417 79686431
Death 29.50 14.09 36 14504 566478 79163370
Nutritional condition abnormal 29.15 14.09 10 14530 1107 79728741
Photophobia 28.15 14.09 26 14514 20502 79709346
Stevens-Johnson syndrome 27.80 14.09 35 14505 39131 79690717
Aspartate aminotransferase increased 27.67 14.09 71 14469 138570 79591278
Renal infarct 26.86 14.09 12 14528 2679 79727169
Alopecia 26.57 14.09 5 14535 231350 79498498
Toxicity to various agents 26.21 14.09 23 14517 421517 79308331
Circulatory collapse 25.69 14.09 33 14507 37635 79692213
Malaise 25.63 14.09 31 14509 489838 79240010
Eosinophilia 25.26 14.09 36 14504 45309 79684539
Haemorrhagic diathesis 25.18 14.09 15 14525 6069 79723779
Polyhydramnios 24.94 14.09 10 14530 1710 79728138
Acute respiratory distress syndrome 24.56 14.09 35 14505 44032 79685816
Premature separation of placenta 24.34 14.09 9 14531 1237 79728611
Live birth 24.28 14.09 23 14517 18721 79711127
Respiratory failure 23.94 14.09 80 14460 180831 79549017
Meningitis 23.43 14.09 17 14523 9565 79720283
Dysphoria 23.13 14.09 13 14527 4721 79725127
Normal newborn 23.10 14.09 15 14525 7057 79722791
Pulmonary physical examination abnormal 22.66 14.09 4 14536 24 79729824
Strongyloidiasis 22.63 14.09 12 14528 3886 79725962
Generalised anxiety disorder 22.58 14.09 10 14530 2187 79727661
Monocytosis 22.25 14.09 8 14532 1016 79728832
Arthropathy 22.19 14.09 3 14537 177108 79552740
Anaphylactic shock 22.17 14.09 30 14510 35966 79693882
Linear IgA disease 22.11 14.09 11 14529 3121 79726727
Endocarditis 21.91 14.09 17 14523 10580 79719268
Product dose omission issue 21.67 14.09 9 14531 247528 79482320
Klebsiella test positive 21.51 14.09 9 14531 1714 79728134
Erythema 21.40 14.09 89 14451 223201 79506647
Skin test positive 21.18 14.09 8 14532 1166 79728682
Oliguria 21.10 14.09 20 14520 16289 79713559
Peripheral swelling 20.29 14.09 12 14528 269605 79460243
Maternal exposure during delivery 20.12 14.09 8 14532 1338 79728510
Arthralgia 19.93 14.09 47 14493 571756 79158092
Guillain-Barre syndrome 19.89 14.09 15 14525 8950 79720898
Completed suicide 19.85 14.09 10 14530 245757 79484091
Stillbirth 19.70 14.09 11 14529 3944 79725904
Clostridium test positive 19.41 14.09 13 14527 6441 79723407
Joint swelling 18.85 14.09 15 14525 288631 79441217
Megacolon 18.17 14.09 10 14530 3485 79726363
Pleural effusion 18.12 14.09 63 14477 145199 79584649
Pain in extremity 18.08 14.09 24 14516 364514 79365334
Hepatotoxicity 17.95 14.09 33 14507 51319 79678529
Bradypnoea 17.75 14.09 12 14528 6040 79723808
Preterm premature rupture of membranes 17.08 14.09 7 14533 1266 79728582
Fall 17.04 14.09 40 14500 487589 79242259
Exposure to SARS-CoV-2 16.91 14.09 8 14532 2036 79727812
Foetal death 16.84 14.09 13 14527 8031 79721817
Bacteraemia 16.74 14.09 25 14515 32799 79697049
Umbilical cord prolapse 16.72 14.09 3 14537 20 79729828
Nephritis 16.43 14.09 10 14530 4204 79725644
Perineal necrosis 16.39 14.09 4 14536 131 79729717
Neonatal disorder 16.36 14.09 3 14537 23 79729825
Sepsis 16.19 14.09 94 14446 269334 79460514
Paraesthesia 16.10 14.09 6 14534 176317 79553531
Staphylococcal scalded skin syndrome 16.05 14.09 5 14535 408 79729440
Uterine contractions abnormal 16.00 14.09 4 14536 145 79729703
Escherichia infection 15.91 14.09 18 14522 17999 79711849
Oligohydramnios 15.67 14.09 9 14531 3403 79726445
Teratoma 15.52 14.09 4 14536 164 79729684
Angioedema 15.22 14.09 39 14501 75996 79653852
Encephalitis 15.22 14.09 16 14524 14744 79715104
Disseminated intravascular coagulation 15.09 14.09 25 14515 35817 79694031
Alanine aminotransferase increased 14.94 14.09 64 14476 162506 79567342
Cervical incompetence 14.86 14.09 5 14535 522 79729326
Sweat test abnormal 14.85 14.09 3 14537 40 79729808
Depressed level of consciousness 14.84 14.09 45 14495 96607 79633241
Pain 14.83 14.09 72 14468 703730 79026118
Meningitis listeria 14.76 14.09 6 14534 1063 79728785
Renal failure 14.70 14.09 74 14466 200894 79528954
Injection site pain 14.49 14.09 3 14537 129835 79600013
Insomnia 14.48 14.09 14 14526 245156 79484692
Clostridium colitis 14.42 14.09 8 14532 2831 79727017
Lymphocyte stimulation test positive 14.42 14.09 6 14534 1127 79728721
Systemic candida 14.39 14.09 11 14529 6695 79723153
Wound infection fungal 14.38 14.09 4 14536 220 79729628
Sinusitis 14.28 14.09 9 14531 195492 79534356

FDA Adverse Event Reporting System (Pediatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Foetal exposure during pregnancy 51.47 19.92 34 835 12807 76116
Drug ineffective 45.70 19.92 53 816 999 87924
Abdominal distension 28.02 19.92 16 853 98 88825
Candida infection 25.71 19.92 14 855 77 88846
Haematochezia 23.83 19.92 9 860 16 88907
Intraventricular haemorrhage 23.40 19.92 16 853 140 88783
Pulmonary haemorrhage 21.61 19.92 21 848 315 88608
Thrombocytopenia 20.93 19.92 12 857 74 88849

Pharmacologic Action:

SourceCodeDescription
ATC J01CA01 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
BETA-LACTAM ANTIBACTERIALS, PENICILLINS
Penicillins with extended spectrum
ATC J01CA51 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
BETA-LACTAM ANTIBACTERIALS, PENICILLINS
Penicillins with extended spectrum
ATC J01CR01 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
BETA-LACTAM ANTIBACTERIALS, PENICILLINS
Combinations of penicillins, incl. beta-lactamase inhibitors
ATC S01AA19 SENSORY ORGANS
OPHTHALMOLOGICALS
ANTIINFECTIVES
Antibiotics
FDA CS M0016152 Penicillins
FDA EPC N0000175497 Penicillin-class Antibacterial
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000890 Anti-Infective Agents
CHEBI has role CHEBI:36047 antibacterial drugs

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Acute otitis media indication 3110003
Septicemia due to Escherichia coli indication 9323009
Bacterial septicemia indication 10001005 DOID:0040085
Gonorrhea indication 15628003 DOID:7551
Haemophilus Influenzae Acute Otitis Media indication 19021002
Infection of skin AND/OR subcutaneous tissue indication 19824006
Acute gonococcal cervicitis indication 20943002 DOID:10615
Acute bacterial epiglottitis indication 21060003
Staphylococcal pneumonia indication 22754005
Streptococcal septicemia indication 29577008
Acute epiglottitis indication 29608009 DOID:9398
Acute gonococcal urethritis indication 29864006
Pneumonia due to Streptococcus indication 34020007
Shigellosis indication 36188001
Sinusitis indication 36971009
Streptococcal tonsillitis indication 41582007
Gonorrhea of rectum indication 42746002
Salmonella septicemia indication 49786009
Pneumococcal meningitis indication 51169003
Bacterial pneumonia indication 53084003 DOID:874
Acute gonococcal endometritis indication 65295003 DOID:7527
Urinary tract infectious disease indication 68566005
Haemophilus influenzae pneumonia indication 70036007
Infection due to Escherichia coli indication 71057007
Rhinoscleroma indication 72409005 DOID:11336
Staphylococcal endocarditis indication 73028002
Acute bacterial sinusitis indication 75498004
Pneumococcal pharyngitis indication 76651006
Cholangitis indication 82403002 DOID:9446
Paratyphoid fever indication 85904008 DOID:3055
Bacterial meningitis indication 95883001 DOID:9470
Dysentery indication 111939009
Female genital tract infection indication 125585007
Infectious disease of abdomen indication 128070006
Infection due to Enterobacteriaceae indication 128945009
Meningococcal meningitis indication 192644005
Escherichia coli meningitis indication 192655005
Bacterial peritonitis indication 197171003
Pneumococcal pneumonia indication 233607000
Proteus septicemia indication 300986008
Proteus urinary tract infection indication 301012009
Bacterial endocarditis indication 301183007
Septicemia due to enterococcus indication 310669007
Bacterial urinary infection indication 312124009
Infective otitis media indication 312218008
Pharyngitis indication 405737000 DOID:2275
Infection due to Staphylococcus aureus indication 406602003
Acute exacerbation of chronic bronchitis indication 425748003
Sepsis due to Staphylococcus aureus indication 448417001
Staphylococcus Acute Otitis Media indication 703469002
Bacteroides Gynecological Infections indication
Skin and Skin Structure Acinetobacter Infection indication
Haemophilus Influenzae Pharyngitis indication
Skin and Skin Structure Proteus Infection indication
Cesarean Section Infection Prevention indication
Streptococcus Pneumoniae Chronic Bronchitis indication
Haemophilus Influenzae Chronic Bronchitis indication
Skin and Skin Structure Bacteroides Fragilis Infection indication
Vaginal Hysterectomy Infection Prevention indication
Pneumococcal Acute Otitis Media indication
Staphylococcus Epidermidis Skin and Skin Structure Infection indication
Streptococcal Endocarditis indication
Bacteroides Peritonitis indication
E. Coli Peritonitis indication
Gastroenteritis due to Salmonella indication
Enterococcus Urinary Tract Infection indication
Neonatal Group B Streptococcal Septicemia indication
Klebsiella Pneumoniae Peritonitis indication
Genitourinary Tract Infections indication
Inflammatory Disease of Female Pelvic Organs indication
Intra-Abdominal E. Coli Abscess indication
E. Coli Gynecological Infections indication
Infection Prevention for GI Surgery indication
Necrotizing enterocolitis in fetus OR newborn off-label use 2707005
Listeriosis off-label use 4241002 DOID:11573
Streptococcal meningitis off-label use 4510004 DOID:11574
Typhoid fever off-label use 4834000 DOID:13258
Pyrexia of unknown origin off-label use 7520000
Inhalational anthrax off-label use 11389007
Listeria meningitis off-label use 31568009 DOID:11572
Pseudotuberculosis off-label use 36753006
Enterocolitis off-label use 43752006
Infection of bone off-label use 111253001
Gastrointestinal anthrax off-label use 111798006 DOID:13386
Infection by Campylobacter fetus off-label use 111835002
Listerial endocarditis off-label use 186318004
Sepsis of the newborn off-label use 206376005
Neonatal pneumonia off-label use 233619008
Human bite - wound off-label use 262555007
Diverticulitis of gastrointestinal tract off-label use 271366000
Neonatal meningitis off-label use 276674008
Dog bite - wound off-label use 283734005
Cat bite - wound off-label use 283782004
Cutaneous listeriosis off-label use 402128003
Anthrax off-label use 409498004 DOID:7427
Pharyngitis due to Haemophilus Parainfluenzae off-label use
Haemophilus Parainfluenzae Chronic Bronchitis off-label use
Listeria Osteomyelitis off-label use
Haemophilus Parainfluenzae Acute Otitis Media off-label use
Diabetic Foot Infection off-label use
Haemophilus Parainfluenzae Pneumonia off-label use
H. Influenzae Meningitis off-label use
Listeria Septic Arthritis off-label use
Granulomatosis Infantiseptica off-label use
Listeria Monocytogenes Septicemia off-label use
Prevention of Neonatal Group B Streptococcal Infection off-label use
Prevention of Bacterial Endocarditis off-label use
Peptic ulcer contraindication 13200003 DOID:750
Acute nephropathy contraindication 58574008
Kidney disease contraindication 90708001 DOID:557
Anemia due to enzyme deficiency contraindication 111577008
Disease of blood AND/OR blood-forming organ contraindication 191124002 DOID:74
Impaired renal function disorder contraindication 197663003
Infectious mononucleosis contraindication 271558008 DOID:8568
Uric acid renal calculus contraindication 274401005
Pseudomembranous enterocolitis contraindication 397683000
Uric Acid Nephropathy Gout contraindication




๐Ÿถ Veterinary Drug Use

SpeciesUseRelation
Cats Skin, Soft Tissue and Post-Surgical Infections caused by Escherichia coli Indication
Cats Skin, Soft Tissue and Post-Surgical Infections caused by Proteus mirabilis Indication
Cats Skin, Soft Tissue and Post-Surgical Infections caused by hemolytic streptococci Indication
Cats Skin, Soft Tissue and Post-Surgical Infections caused by Staphylococcus spp Indication
Cats Skin, Soft Tissue and Post-Surgical Infections caused by Pasteurella spp Indication
Cats Urinary Tract Infections caused by Proteus mirabilis Indication
Cats Urinary Tract Infections caused by Escherichia coli Indication
Cats Urinary tract infections caused by Staphylococcus species Indication
Cats Urinary Tract Infections caused by hemolytic streptococci Indication
Cats Urinary Tract Infections caused by Enterococcus spp Indication
Cats Upper respiratory infections caused by hemolytic streptococci Indication
Cats Upper respiratory infections caused by Staphylococcus aureus Indication
Cats Upper respiratory infections caused by Escherichia coli Indication
Cats Upper respiratory infections caused by Proteus mirabilis Indication
Cats Upper respiratory infections caused by Pasteurella spp Indication
Cats Gastrointestinal Infections caused by Enterococcus spp Indication
Cats Gastrointestinal Infections caused by Staphylococcus spp Indication
Cats Gastrointestinal Infections caused by Escherichia coli Indication
Cats Tonsillitis caused by Escherichia coli Indication
Cats Tonsillitis caused by hemolytic streptococci Indication
Cats Tonsillitis caused by Pasteurella spp Indication
Cats Tonsillitis caused by Proteus mirabilis Indication
Cats Tonsillitis caused by Staphylococcus aureus Indication
Cats Bronchopneumonia caused by Escherichia coli Indication
Cats Bronchopneumonia caused by hemolytic streptococci Indication
Cats Bronchopneumonia caused by Pasteurella spp Indication
Cats Bronchopneumonia caused by Proteus mirabilis Indication
Cats Bronchopneumonia caused by Staphylococcus aureus Indication
Cats Abscesses caused by hemolytic streptococci Indication
Cats Abscesses caused by Escherichia coli Indication
Cats Abscesses caused by Pasteurella spp Indication
Cats Abscesses caused by Proteus mirabilis Indication
Cats Abscesses caused by Staphylococcus spp Indication
Cats Pustular dermatitis caused by hemolytic streptococci Indication
Cats Pustular dermatitis caused by Escherichia coli Indication
Cats Pustular dermatitis caused by Pasteurella spp Indication
Cats Pustular dermatitis caused by Proteus mirabilis Indication
Cats Pustular dermatitis caused by Staphylococcus spp Indication
Cats Cellulitis caused by hemolytic streptococci Indication
Cats Cellulitis caused by Escherichia coli Indication
Cats Cellulitis caused by Pasteurella spp Indication
Cats Cellulitis caused by Proteus mirabilis Indication
Cats Cellulitis caused by Staphylococcus spp Indication
Cats Infections of the anal gland caused by hemolytic streptococci Indication
Cats Infections of the anal gland caused by Escherichia coli Indication
Cats Infections of the anal gland caused by Pasteurella spp Indication
Cats Infections of the anal gland caused by Proteus mirabilis Indication
Cats Infections of the anal gland caused by Staphylococcus spp Indication
Cattle Bacterial pneumonia caused by Aerobacter spp Indication
Cattle Bacterial pneumonia caused by Klebsiella spp Indication
Cattle Bacterial pneumonia caused by Staphylococcus spp Indication
Cattle Bacterial pneumonia caused by Streptococcus spp Indication
Cattle Bacterial pneumonia caused by Pasteurella multocida Indication
Cattle Bacterial pneumonia caused by Escherichia coli Indication
Dogs Skin, Soft Tissue and Post-Surgical Infections caused by Escherichia coli Indication
Dogs Skin, Soft Tissue and Post-Surgical Infections caused by Proteus mirabilis Indication
Dogs Skin, Soft Tissue and Post-Surgical Infections caused by hemolytic streptococci Indication
Dogs Skin, Soft Tissue and Post-Surgical Infections caused by Staphylococcus spp Indication
Dogs Skin, Soft Tissue and Post-Surgical Infections caused by hemolytic streptococci Indication
Dogs Upper respiratory infections caused by hemolytic streptococci Indication
Dogs Upper respiratory infections caused by Staphylococcus aureus Indication
Dogs Upper respiratory infections caused by Escherichia coli Indication
Dogs Upper respiratory infections caused by Proteus mirabilis Indication
Dogs Upper respiratory infections caused by Pasteurella spp Indication
Dogs Urinary Tract Infections caused by Proteus mirabilis Indication
Dogs Urinary Tract Infections caused by Escherichia coli Indication
Dogs Urinary tract infections caused by Staphylococcus species Indication
Dogs Urinary Tract Infections caused by hemolytic streptococci Indication
Dogs Urinary Tract Infections caused by Enterococcus spp Indication
Dogs Gastrointestinal Infections caused by Enterococcus spp Indication
Dogs Gastrointestinal Infections caused by Staphylococcus spp Indication
Dogs Gastrointestinal Infections caused by Escherichia coli Indication
Dogs Tonsillitis caused by Escherichia coli Indication
Dogs Tonsillitis caused by hemolytic streptococci Indication
Dogs Tonsillitis caused by Pasteurella spp Indication
Dogs Tonsillitis caused by Proteus mirabilis Indication
Dogs Tonsillitis caused by Staphylococcus aureus Indication
Dogs Bronchopneumonia caused by Escherichia coli Indication
Dogs Bronchopneumonia caused by hemolytic streptococci Indication
Dogs Bronchopneumonia caused by Pasteurella spp Indication
Dogs Bronchopneumonia caused by Proteus mirabilis Indication
Dogs Bronchopneumonia caused by Staphylococcus aureus Indication
Dogs Abscesses caused by Staphylococcus spp Indication
Dogs Pustular dermatitis caused by Staphylococcus spp Indication
Dogs Cellulitis caused by Staphylococcus spp Indication
Dogs Infections of the anal gland caused by Staphylococcus spp Indication
Dogs Abscesses caused by hemolytic streptococci Indication
Dogs Abscesses caused by Escherichia coli Indication
Dogs Abscesses caused by hemolytic streptococci Indication
Dogs Abscesses caused by Proteus mirabilis Indication
Dogs Pustular dermatitis caused by hemolytic streptococci Indication
Dogs Pustular dermatitis caused by Escherichia coli Indication
Dogs Pustular dermatitis caused by hemolytic streptococci Indication
Dogs Pustular dermatitis caused by Proteus mirabilis Indication
Dogs Cellulitis caused by hemolytic streptococci Indication
Dogs Cellulitis caused by Escherichia coli Indication
Dogs Cellulitis caused by hemolytic streptococci Indication
Dogs Cellulitis caused by Proteus mirabilis Indication
Dogs Infections of the anal gland caused by hemolytic streptococci Indication
Dogs Infections of the anal gland caused by Escherichia coli Indication
Dogs Infections of the anal gland caused by hemolytic streptococci Indication
Dogs Infections of the anal gland caused by Proteus mirabilis Indication
Horses Respiratory tract infections caused by Staphylococcus species Indication
Horses Respiratory tract infections caused by Escherichia coli Indication
Horses Respiratory tract infections caused by Proteus mirabilis Indication
Horses Skin and soft tissue infections caused by Staphylococcus spp Indication
Horses Skin and soft tissue infections caused by Streptococcus spp Indication
Horses Skin and soft tissue infections caused by Escherichia coli Indication
Horses Skin and soft tissue infections caused by Proteus mirabilis Indication

๐Ÿถ Veterinary products

ProductApplicantIngredients
Omnipen 250 mg Zoetis Inc. 1
Polyflex Boehringer lngelheim Animal Health USA Inc. 1
Ampi-Tab Zoetis Inc. 1
Princillin Injection Zoetis Inc. 1
Princillin Injection Zoetis Inc. 1
Princillin Injection 200 mg Zoetis Inc. 1
Ampi-Bol Zoetis Inc. 1
Ampi-Ject Zoetis Inc. 1
Amp-Equine Zoetis Inc. 1
Ampicillin Trihydrate HQ Specialty Pharma Corp. 1
Ampicillin Sodium HQ Specialty Pharma Corp. 1

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 2.79 acidic
pKa2 7.67 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Angiopoietin-1 receptor Kinase Kd 4.09 CHEMBL
Transient receptor potential cation channel subfamily M member 4 Ion channel IC50 4.72 CHEMBL
Bacterial penicillin-binding protein Enzyme INHIBITOR CHEMBL CHEMBL
Penicillin-binding protein 1A Enzyme WOMBAT-PK

External reference:

IDSource
4017545 VUID
N0000145927 NUI
D01251 KEGG_DRUG
69-52-3 SECONDARY_CAS_RN
7177-48-2 SECONDARY_CAS_RN
203115 RXNORM
C0002680 UMLSCUI
CHEBI:28971 CHEBI
AIC PDB_CHEM_ID
CHEMBL174 ChEMBL_ID
DB00415 DRUGBANK_ID
CHEMBL1200758 ChEMBL_ID
CHEMBL453388 ChEMBL_ID
D000667 MESH_DESCRIPTOR_UI
6249 PUBCHEM_CID
10896 IUPHAR_LIGAND_ID
1339 INN_ID
7C782967RD UNII
17720 MMSL
3783 MMSL
4194 MMSL
4195 MMSL
71827 MMSL
d00003 MMSL
1268946000 SNOMEDCT_US
31087008 SNOMEDCT_US
387170002 SNOMEDCT_US
96070009 SNOMEDCT_US
96071008 SNOMEDCT_US
4017543 VANDF
4017544 VANDF
4017545 VANDF
002692 NDDF
002693 NDDF
002694 NDDF
002695 NDDF

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
UNASYN HUMAN PRESCRIPTION DRUG LABEL 2 0049-0013 INJECTION, POWDER, FOR SOLUTION 1 g INTRAMUSCULAR NDA 26 sections
UNASYN HUMAN PRESCRIPTION DRUG LABEL 2 0049-0013 INJECTION, POWDER, FOR SOLUTION 1 g INTRAMUSCULAR NDA 26 sections
UNASYN HUMAN PRESCRIPTION DRUG LABEL 2 0049-0014 INJECTION, POWDER, FOR SOLUTION 2 g INTRAMUSCULAR NDA 26 sections
UNASYN HUMAN PRESCRIPTION DRUG LABEL 2 0049-0014 INJECTION, POWDER, FOR SOLUTION 2 g INTRAMUSCULAR NDA 26 sections
UNASYN HUMAN PRESCRIPTION DRUG LABEL 2 0049-0024 INJECTION, POWDER, FOR SOLUTION 100 mg INTRAMUSCULAR NDA 25 sections
UNASYN HUMAN PRESCRIPTION DRUG LABEL 2 0049-0024 INJECTION, POWDER, FOR SOLUTION 100 mg INTRAMUSCULAR NDA 25 sections
UNASYN HUMAN PRESCRIPTION DRUG LABEL 2 0049-0031 INJECTION, POWDER, FOR SOLUTION 1 g INTRAMUSCULAR ANDA 26 sections
UNASYN HUMAN PRESCRIPTION DRUG LABEL 2 0049-0031 INJECTION, POWDER, FOR SOLUTION 1 g INTRAMUSCULAR ANDA 26 sections
UNASYN HUMAN PRESCRIPTION DRUG LABEL 2 0049-0032 INJECTION, POWDER, FOR SOLUTION 2 g INTRAMUSCULAR ANDA 26 sections
UNASYN HUMAN PRESCRIPTION DRUG LABEL 2 0049-0032 INJECTION, POWDER, FOR SOLUTION 2 g INTRAMUSCULAR ANDA 26 sections
AMPICILLIN HUMAN PRESCRIPTION DRUG LABEL 1 0404-9816 INJECTION, POWDER, FOR SOLUTION 1 g INTRAMUSCULAR ANDA 13 sections
AMPICILLIN HUMAN PRESCRIPTION DRUG LABEL 1 0404-9816 INJECTION, POWDER, FOR SOLUTION 1 g INTRAMUSCULAR ANDA 13 sections
AMPICILLIN HUMAN PRESCRIPTION DRUG LABEL 1 0404-9816 INJECTION, POWDER, FOR SOLUTION 1 g INTRAMUSCULAR ANDA 13 sections
AMPICILLIN HUMAN PRESCRIPTION DRUG LABEL 1 0404-9817 INJECTION, POWDER, FOR SOLUTION 500 mg INTRAMUSCULAR ANDA 13 sections
AMPICILLIN HUMAN PRESCRIPTION DRUG LABEL 1 0404-9818 INJECTION, POWDER, FOR SOLUTION 2 g INTRAVENOUS ANDA 13 sections
AMPICILLIN HUMAN PRESCRIPTION DRUG LABEL 1 0404-9818 INJECTION, POWDER, FOR SOLUTION 2 g INTRAVENOUS ANDA 13 sections
AMPICILLIN HUMAN PRESCRIPTION DRUG LABEL 1 0404-9818 INJECTION, POWDER, FOR SOLUTION 2 g INTRAVENOUS ANDA 13 sections
Ampicillin and Sulbactam HUMAN PRESCRIPTION DRUG LABEL 2 0409-2689 INJECTION, POWDER, FOR SOLUTION 1 g INTRAVENOUS ANDA 25 sections
Ampicillin and Sulbactam HUMAN PRESCRIPTION DRUG LABEL 2 0409-2689 INJECTION, POWDER, FOR SOLUTION 1 g INTRAVENOUS ANDA 25 sections
Ampicillin and Sulbactam HUMAN PRESCRIPTION DRUG LABEL 2 0409-2987 INJECTION, POWDER, FOR SOLUTION 2 g INTRAVENOUS ANDA 25 sections
Ampicillin and Sulbactam HUMAN PRESCRIPTION DRUG LABEL 2 0409-2987 INJECTION, POWDER, FOR SOLUTION 2 g INTRAVENOUS ANDA 25 sections
Ampicillin HUMAN PRESCRIPTION DRUG LABEL 1 0409-3718 INJECTION, POWDER, FOR SOLUTION 500 mg INTRAVENOUS ANDA 23 sections
Ampicillin HUMAN PRESCRIPTION DRUG LABEL 1 0409-3718 INJECTION, POWDER, FOR SOLUTION 500 mg INTRAVENOUS ANDA 23 sections
Ampicillin HUMAN PRESCRIPTION DRUG LABEL 1 0409-3719 INJECTION, POWDER, FOR SOLUTION 250 mg INTRAVENOUS ANDA 23 sections
Ampicillin HUMAN PRESCRIPTION DRUG LABEL 1 0409-3719 INJECTION, POWDER, FOR SOLUTION 250 mg INTRAVENOUS ANDA 23 sections
Ampicillin HUMAN PRESCRIPTION DRUG LABEL 1 0409-3720 INJECTION, POWDER, FOR SOLUTION 2 g INTRAVENOUS ANDA 23 sections
Ampicillin HUMAN PRESCRIPTION DRUG LABEL 1 0409-3720 INJECTION, POWDER, FOR SOLUTION 2 g INTRAVENOUS ANDA 23 sections
Ampicillin HUMAN PRESCRIPTION DRUG LABEL 1 0409-3725 INJECTION, POWDER, FOR SOLUTION 10 g INTRAVENOUS ANDA 22 sections
Ampicillin HUMAN PRESCRIPTION DRUG LABEL 1 0409-3726 INJECTION, POWDER, FOR SOLUTION 1 g INTRAVENOUS ANDA 23 sections
Ampicillin HUMAN PRESCRIPTION DRUG LABEL 1 0409-3726 INJECTION, POWDER, FOR SOLUTION 1 g INTRAVENOUS ANDA 23 sections