Stem definition | Drug id | CAS RN |
---|---|---|
angiotensin II receptor antagonists, antihypertensive (non-peptidic) | 1985 | 144689-63-4 |
Dose | Unit | Route |
---|---|---|
20 | mg | O |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 1 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 2 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 0 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 1.02 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 26 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Date | Agency | Company | Orphan |
---|---|---|---|
April 25, 2002 | FDA | DAIICHI SANKYO |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Sprue-like enteropathy | 551.58 | 11 | 113 | 30550 | 410 | 50574051 |
Malabsorption | 379.91 | 11 | 125 | 30538 | 3581 | 50570880 |
Intestinal villi atrophy | 133.19 | 11 | 29 | 30634 | 150 | 50574311 |
Hyperkalaemia | 89.26 | 11 | 127 | 30536 | 47962 | 50526499 |
Dehydration | 81.88 | 11 | 240 | 30423 | 152209 | 50422252 |
Colitis microscopic | 75.85 | 11 | 48 | 30615 | 6472 | 50567989 |
Acute kidney injury | 70.39 | 11 | 299 | 30364 | 227759 | 50346702 |
Coeliac disease | 63.40 | 11 | 48 | 30615 | 8637 | 50565824 |
Renal failure | 62.19 | 11 | 173 | 30490 | 106460 | 50468001 |
Systemic lupus erythematosus | 56.07 | 11 | 9 | 30654 | 140613 | 50433848 |
Device related thrombosis | 55.28 | 11 | 23 | 30640 | 1284 | 50573177 |
Treatment failure | 54.45 | 11 | 9 | 30654 | 137628 | 50436833 |
Diarrhoea | 54.24 | 11 | 569 | 30094 | 587907 | 49986554 |
Synovitis | 53.97 | 11 | 6 | 30657 | 123859 | 50450602 |
Hyponatraemia | 53.14 | 11 | 153 | 30510 | 95986 | 50478475 |
Blood pressure increased | 51.08 | 11 | 187 | 30476 | 132945 | 50441516 |
Hypertensive crisis | 47.99 | 11 | 49 | 30614 | 13105 | 50561356 |
Drug ineffective | 47.01 | 11 | 298 | 30365 | 819035 | 49755426 |
Wound | 46.41 | 11 | 5 | 30658 | 105789 | 50468672 |
Infusion related reaction | 45.42 | 11 | 23 | 30640 | 169534 | 50404927 |
Off label use | 44.26 | 11 | 144 | 30519 | 474282 | 50100179 |
Gallbladder polyp | 42.05 | 11 | 16 | 30647 | 705 | 50573756 |
Hypertensive emergency | 41.96 | 11 | 20 | 30643 | 1543 | 50572918 |
Completed suicide | 41.60 | 11 | 14 | 30649 | 131875 | 50442586 |
Bradycardia | 41.02 | 11 | 108 | 30555 | 64318 | 50510143 |
Therapeutic product effect decreased | 40.28 | 11 | 16 | 30647 | 136034 | 50438427 |
Cerebral infarction | 39.98 | 11 | 57 | 30606 | 21547 | 50552914 |
Maternal exposure during pregnancy | 39.43 | 11 | 24 | 30639 | 159754 | 50414707 |
Drug intolerance | 39.20 | 11 | 45 | 30618 | 219059 | 50355402 |
Renal impairment | 38.55 | 11 | 117 | 30546 | 75544 | 50498917 |
Lower respiratory tract infection | 38.15 | 11 | 6 | 30657 | 95195 | 50479266 |
Dizziness | 36.15 | 11 | 344 | 30319 | 346025 | 50228436 |
Product use issue | 36.12 | 11 | 23 | 30640 | 149452 | 50425009 |
Hypotension | 35.96 | 11 | 255 | 30408 | 235214 | 50339247 |
Collagen disorder | 34.81 | 11 | 10 | 30653 | 179 | 50574282 |
Contraindicated product administered | 34.54 | 11 | 24 | 30639 | 148934 | 50425527 |
Oligohydramnios | 33.85 | 11 | 28 | 30635 | 5722 | 50568739 |
Blood urea increased | 33.44 | 11 | 55 | 30608 | 23530 | 50550931 |
Metabolic acidosis | 30.99 | 11 | 71 | 30592 | 38754 | 50535707 |
Glossodynia | 30.45 | 11 | 16 | 30647 | 115553 | 50458908 |
Weight decreased | 30.01 | 11 | 233 | 30430 | 221012 | 50353449 |
Blood pressure decreased | 29.93 | 11 | 88 | 30575 | 55821 | 50518640 |
Renal disorder | 29.78 | 11 | 57 | 30606 | 27448 | 50547013 |
Pancreatic toxicity | 29.23 | 11 | 6 | 30657 | 22 | 50574439 |
Toxicity to various agents | 28.81 | 11 | 53 | 30610 | 212446 | 50362015 |
Arthropathy | 27.62 | 11 | 33 | 30630 | 157873 | 50416588 |
Blood pressure inadequately controlled | 27.19 | 11 | 22 | 30641 | 4358 | 50570103 |
Gastritis | 27.08 | 11 | 61 | 30602 | 32922 | 50541539 |
Microvillous inclusion disease | 26.91 | 11 | 5 | 30658 | 9 | 50574452 |
Swelling | 26.43 | 11 | 51 | 30612 | 200821 | 50373640 |
Lymphocytic infiltration | 26.35 | 11 | 12 | 30651 | 834 | 50573627 |
Gravitational oedema | 25.58 | 11 | 13 | 30650 | 1152 | 50573309 |
Asthenia | 25.34 | 11 | 300 | 30363 | 318742 | 50255719 |
Hypokalaemia | 25.25 | 11 | 113 | 30550 | 87879 | 50486582 |
Cardiac failure congestive | 24.70 | 11 | 109 | 30554 | 84273 | 50490188 |
Joint swelling | 24.54 | 11 | 72 | 30591 | 245214 | 50329247 |
Blood creatinine increased | 24.31 | 11 | 101 | 30562 | 76059 | 50498402 |
Syncope | 24.30 | 11 | 125 | 30538 | 102877 | 50471584 |
Gastrooesophageal reflux disease | 22.57 | 11 | 99 | 30564 | 76329 | 50498132 |
Autoimmune enteropathy | 21.98 | 11 | 4 | 30659 | 6 | 50574455 |
Putamen haemorrhage | 21.91 | 11 | 7 | 30656 | 182 | 50574279 |
Enteritis | 21.86 | 11 | 24 | 30639 | 6971 | 50567490 |
Diverticulum | 21.12 | 11 | 29 | 30634 | 10585 | 50563876 |
Spleen congestion | 20.36 | 11 | 6 | 30657 | 118 | 50574343 |
Pain | 19.90 | 11 | 240 | 30423 | 578663 | 49995798 |
Death | 19.74 | 11 | 116 | 30547 | 325263 | 50249198 |
Condition aggravated | 19.60 | 11 | 103 | 30560 | 296955 | 50277506 |
Heart rate irregular | 19.60 | 11 | 39 | 30624 | 19321 | 50555140 |
Eosinophil count | 19.23 | 11 | 3 | 30660 | 0 | 50574461 |
Coronary artery disease | 19.08 | 11 | 50 | 30613 | 29676 | 50544785 |
Oesophagitis | 18.69 | 11 | 31 | 30632 | 13352 | 50561109 |
Discomfort | 18.57 | 11 | 23 | 30640 | 108357 | 50466104 |
Burn oesophageal | 18.42 | 11 | 6 | 30657 | 166 | 50574295 |
Exposure during pregnancy | 18.40 | 11 | 28 | 30635 | 120987 | 50453474 |
Atrial tachycardia | 18.31 | 11 | 13 | 30650 | 2119 | 50572342 |
Alopecia | 17.87 | 11 | 82 | 30581 | 244965 | 50329496 |
Decreased appetite | 17.76 | 11 | 193 | 30470 | 200730 | 50373731 |
Large intestine polyp | 17.64 | 11 | 22 | 30641 | 7310 | 50567151 |
Liver disorder | 17.50 | 11 | 56 | 30607 | 37166 | 50537295 |
Prerenal failure | 17.39 | 11 | 11 | 30652 | 1482 | 50572979 |
Nail disorder | 17.06 | 11 | 25 | 30638 | 9683 | 50564778 |
Gastritis erosive | 16.71 | 11 | 18 | 30645 | 5116 | 50569345 |
Anti-transglutaminase antibody increased | 16.69 | 11 | 3 | 30660 | 4 | 50574457 |
Aortic valve calcification | 16.67 | 11 | 7 | 30656 | 400 | 50574061 |
Hyperuricaemia | 16.29 | 11 | 17 | 30646 | 4663 | 50569798 |
Chronic kidney disease | 16.19 | 11 | 57 | 30606 | 39714 | 50534747 |
Abortion spontaneous | 15.92 | 11 | 3 | 30660 | 41769 | 50532692 |
Febrile neutropenia | 15.43 | 11 | 22 | 30641 | 97645 | 50476816 |
Hiatus hernia | 15.14 | 11 | 34 | 30629 | 18310 | 50556151 |
Oedema peripheral | 15.01 | 11 | 154 | 30509 | 157807 | 50416654 |
Azotaemia | 14.74 | 11 | 15 | 30648 | 3993 | 50570468 |
Enterocolitis | 14.69 | 11 | 19 | 30644 | 6548 | 50567913 |
Product administration error | 14.60 | 11 | 35 | 30628 | 19664 | 50554797 |
Distributive shock | 14.55 | 11 | 8 | 30655 | 832 | 50573629 |
Helicobacter infection | 14.45 | 11 | 6 | 30657 | 49696 | 50524765 |
Blood glucose increased | 14.41 | 11 | 83 | 30580 | 71241 | 50503220 |
Electrolyte imbalance | 14.37 | 11 | 32 | 30631 | 17137 | 50557324 |
Aortic dissection | 14.29 | 11 | 10 | 30653 | 1593 | 50572868 |
Hepatic enzyme abnormal | 14.06 | 11 | 16 | 30647 | 4833 | 50569628 |
Hepatorenal failure | 14.04 | 11 | 7 | 30656 | 596 | 50573865 |
Skin exfoliation | 13.53 | 11 | 48 | 30615 | 33564 | 50540897 |
Acquired oesophageal web | 13.48 | 11 | 5 | 30658 | 205 | 50574256 |
Product use in unapproved indication | 13.07 | 11 | 32 | 30631 | 115787 | 50458674 |
Chronic gastritis | 12.98 | 11 | 11 | 30652 | 2323 | 50572138 |
Abdominal discomfort | 12.78 | 11 | 85 | 30578 | 231556 | 50342905 |
Musculoskeletal stiffness | 12.62 | 11 | 38 | 30625 | 128443 | 50446018 |
Iron deficiency anaemia | 12.57 | 11 | 30 | 30633 | 16804 | 50557657 |
Infection | 12.52 | 11 | 58 | 30605 | 172896 | 50401565 |
Chest pain | 12.15 | 11 | 162 | 30501 | 176720 | 50397741 |
Hepatitis alcoholic | 12.07 | 11 | 4 | 30659 | 117 | 50574344 |
Hypovolaemia | 12.00 | 11 | 21 | 30642 | 9444 | 50565017 |
Pharyngeal haematoma | 11.96 | 11 | 3 | 30660 | 31 | 50574430 |
Leukopenia | 11.91 | 11 | 14 | 30649 | 67514 | 50506947 |
Purpura senile | 11.90 | 11 | 6 | 30657 | 523 | 50573938 |
Mucosa vesicle | 11.88 | 11 | 3 | 30660 | 32 | 50574429 |
Confabulation | 11.82 | 11 | 5 | 30658 | 291 | 50574170 |
Blood creatine phosphokinase increased | 11.79 | 11 | 39 | 30624 | 26328 | 50548133 |
Impaired healing | 11.75 | 11 | 15 | 30648 | 69771 | 50504690 |
Renal artery stenosis | 11.67 | 11 | 9 | 30654 | 1663 | 50572798 |
Withdrawal hypertension | 11.67 | 11 | 4 | 30659 | 130 | 50574331 |
Myocardial infarction | 11.62 | 11 | 93 | 30570 | 88934 | 50485527 |
Intentional product use issue | 11.50 | 11 | 18 | 30645 | 76900 | 50497561 |
General physical health deterioration | 11.39 | 11 | 46 | 30617 | 142388 | 50432073 |
Feeling abnormal | 11.28 | 11 | 121 | 30542 | 125371 | 50449090 |
Anaemia | 11.22 | 11 | 215 | 30448 | 252241 | 50322220 |
Neutropenia | 11.08 | 11 | 49 | 30614 | 147916 | 50426545 |
Bradyphrenia | 11.04 | 11 | 16 | 30647 | 6136 | 50568325 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Sprue-like enteropathy | 393.16 | 11.79 | 85 | 20629 | 355 | 29553458 |
Malabsorption | 339.67 | 11.79 | 102 | 20612 | 1846 | 29551967 |
Colitis microscopic | 79.99 | 11.79 | 34 | 20680 | 1729 | 29552084 |
Gastrointestinal disorder | 75.90 | 11.79 | 97 | 20617 | 28609 | 29525204 |
Intestinal villi atrophy | 60.99 | 11.79 | 15 | 20699 | 121 | 29553692 |
Renal impairment | 57.35 | 11.79 | 155 | 20559 | 81178 | 29472635 |
Coeliac disease | 50.41 | 11.79 | 18 | 20696 | 570 | 29553243 |
Death | 50.10 | 11.79 | 103 | 20611 | 341981 | 29211832 |
Toxicity to various agents | 49.84 | 11.79 | 30 | 20684 | 173631 | 29380182 |
Blood pressure increased | 42.66 | 11.79 | 131 | 20583 | 73672 | 29480141 |
Hypotension | 39.65 | 11.79 | 252 | 20462 | 194102 | 29359711 |
Dehydration | 36.43 | 11.79 | 168 | 20546 | 114580 | 29439233 |
Blood pressure decreased | 35.42 | 11.79 | 90 | 20624 | 45387 | 29508426 |
Hepatic function abnormal | 35.17 | 11.79 | 82 | 20632 | 39177 | 29514636 |
Dizziness | 33.88 | 11.79 | 238 | 20476 | 189446 | 29364367 |
Diarrhoea | 32.70 | 11.79 | 366 | 20348 | 332332 | 29221481 |
Off label use | 31.45 | 11.79 | 107 | 20607 | 300693 | 29253120 |
Syncope | 31.07 | 11.79 | 126 | 20588 | 81245 | 29472568 |
Cerebral infarction | 29.55 | 11.79 | 58 | 20656 | 24617 | 29529196 |
Pulmonary hypoplasia | 28.98 | 11.79 | 11 | 20703 | 415 | 29553398 |
Hyperkinetic heart syndrome | 28.67 | 11.79 | 8 | 20706 | 110 | 29553703 |
Intestinal intraepithelial lymphocytes increased | 28.39 | 11.79 | 5 | 20709 | 4 | 29553809 |
Interstitial lung disease | 26.67 | 11.79 | 95 | 20619 | 57623 | 29496190 |
Gastrointestinal erosion | 26.43 | 11.79 | 10 | 20704 | 374 | 29553439 |
Right atrial hypertrophy | 26.41 | 11.79 | 11 | 20703 | 531 | 29553282 |
Hyperkalaemia | 24.98 | 11.79 | 97 | 20617 | 61295 | 29492518 |
Weight decreased | 24.98 | 11.79 | 186 | 20528 | 150719 | 29403094 |
Hypertensive crisis | 24.74 | 11.79 | 29 | 20685 | 7819 | 29545994 |
Microvillous inclusion disease | 24.44 | 11.79 | 6 | 20708 | 48 | 29553765 |
Neutropenia | 24.40 | 11.79 | 34 | 20680 | 131677 | 29422136 |
Hyperuricaemia | 24.33 | 11.79 | 27 | 20687 | 6862 | 29546951 |
Completed suicide | 22.65 | 11.79 | 18 | 20696 | 90228 | 29463585 |
Drug abuse | 22.60 | 11.79 | 14 | 20700 | 79869 | 29473944 |
Gastrooesophageal reflux disease | 22.13 | 11.79 | 60 | 20654 | 31436 | 29522377 |
Transient aphasia | 20.77 | 11.79 | 6 | 20708 | 94 | 29553719 |
Anaplastic astrocytoma | 19.74 | 11.79 | 6 | 20708 | 113 | 29553700 |
Bronchial wall thickening | 19.48 | 11.79 | 11 | 20703 | 1041 | 29552772 |
Drug ineffective | 19.03 | 11.79 | 163 | 20551 | 363007 | 29190806 |
Coronary artery occlusion | 19.01 | 11.79 | 29 | 20685 | 10065 | 29543748 |
Tropical sprue | 18.79 | 11.79 | 3 | 20711 | 0 | 29553813 |
Bronchial secretion retention | 18.54 | 11.79 | 11 | 20703 | 1142 | 29552671 |
Haemorrhoids | 18.54 | 11.79 | 31 | 20683 | 11626 | 29542187 |
Right ventricular hypertrophy | 18.47 | 11.79 | 11 | 20703 | 1150 | 29552663 |
Loss of consciousness | 18.23 | 11.79 | 101 | 20613 | 73955 | 29479858 |
Oligohydramnios | 17.47 | 11.79 | 7 | 20707 | 306 | 29553507 |
Acute kidney injury | 17.27 | 11.79 | 271 | 20443 | 264996 | 29288817 |
Infective exacerbation of chronic obstructive airways disease | 17.24 | 11.79 | 12 | 20702 | 1638 | 29552175 |
Product use in unapproved indication | 16.50 | 11.79 | 22 | 20692 | 86853 | 29466960 |
Lymphangiectasia intestinal | 16.26 | 11.79 | 3 | 20711 | 4 | 29553809 |
Aortic valve stenosis | 16.23 | 11.79 | 13 | 20701 | 2195 | 29551618 |
Hypertensive emergency | 16.18 | 11.79 | 9 | 20705 | 827 | 29552986 |
Hospitalisation | 16.14 | 11.79 | 6 | 20708 | 45982 | 29507831 |
Hypokalaemia | 15.52 | 11.79 | 73 | 20641 | 50130 | 29503683 |
Renal failure | 15.19 | 11.79 | 138 | 20576 | 118461 | 29435352 |
Collagen disorder | 14.86 | 11.79 | 5 | 20709 | 132 | 29553681 |
Gout | 14.78 | 11.79 | 35 | 20679 | 16876 | 29536937 |
Pulmonary function test abnormal | 14.75 | 11.79 | 12 | 20702 | 2070 | 29551743 |
Atrophy | 14.58 | 11.79 | 9 | 20705 | 1004 | 29552809 |
Histology abnormal | 14.42 | 11.79 | 6 | 20708 | 289 | 29553524 |
Intestinal ulcer perforation | 13.78 | 11.79 | 3 | 20711 | 13 | 29553800 |
Febrile neutropenia | 13.77 | 11.79 | 37 | 20677 | 112203 | 29441610 |
Enterocolitis viral | 13.77 | 11.79 | 4 | 20710 | 64 | 29553749 |
Obstruction | 13.44 | 11.79 | 11 | 20703 | 1915 | 29551898 |
Palmar-plantar erythrodysaesthesia syndrome | 13.39 | 11.79 | 31 | 20683 | 14728 | 29539085 |
Echocardiogram abnormal | 13.20 | 11.79 | 8 | 20706 | 863 | 29552950 |
Chronic gastritis | 13.14 | 11.79 | 9 | 20705 | 1197 | 29552616 |
Rectal ulcer haemorrhage | 12.94 | 11.79 | 4 | 20710 | 80 | 29553733 |
Treatment failure | 12.66 | 11.79 | 5 | 20709 | 36934 | 29516879 |
Hypertension | 12.62 | 11.79 | 131 | 20583 | 116483 | 29437330 |
Erosive duodenitis | 12.49 | 11.79 | 9 | 20705 | 1298 | 29552515 |
Gastric cancer | 12.34 | 11.79 | 16 | 20698 | 4778 | 29549035 |
Cerebral haemorrhage | 12.24 | 11.79 | 49 | 20665 | 31377 | 29522436 |
Thrombocytopenia | 12.06 | 11.79 | 51 | 20663 | 134772 | 29419041 |
Prerenal failure | 12.03 | 11.79 | 10 | 20704 | 1778 | 29552035 |
Herpes ophthalmic | 11.91 | 11.79 | 6 | 20708 | 451 | 29553362 |
Product administration error | 11.84 | 11.79 | 29 | 20685 | 14281 | 29539532 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Sprue-like enteropathy | 908.61 | 10.54 | 194 | 41406 | 835 | 64456297 |
Malabsorption | 545.26 | 10.54 | 174 | 41426 | 4229 | 64452903 |
Intestinal villi atrophy | 184.87 | 10.54 | 44 | 41556 | 334 | 64456798 |
Colitis microscopic | 147.23 | 10.54 | 79 | 41521 | 7353 | 64449779 |
Dehydration | 101.55 | 10.54 | 339 | 41261 | 216424 | 64240708 |
Hyperkalaemia | 101.02 | 10.54 | 210 | 41390 | 100919 | 64356213 |
Coeliac disease | 94.08 | 10.54 | 59 | 41541 | 7353 | 64449779 |
Renal impairment | 90.67 | 10.54 | 240 | 41360 | 134777 | 64322355 |
Diarrhoea | 88.38 | 10.54 | 779 | 40821 | 721925 | 63735207 |
Gastrointestinal disorder | 74.50 | 10.54 | 173 | 41427 | 89536 | 64367596 |
Toxicity to various agents | 74.28 | 10.54 | 75 | 41525 | 363438 | 64093694 |
Completed suicide | 69.28 | 10.54 | 29 | 41571 | 224385 | 64232747 |
Hypertensive crisis | 68.41 | 10.54 | 71 | 41529 | 18177 | 64438955 |
Renal failure | 67.05 | 10.54 | 263 | 41337 | 181425 | 64275707 |
Cerebral infarction | 66.22 | 10.54 | 105 | 41495 | 40939 | 64416193 |
Hypotension | 63.10 | 10.54 | 441 | 41159 | 380533 | 64076599 |
Off label use | 62.48 | 10.54 | 205 | 41395 | 632601 | 63824531 |
Hypertensive emergency | 56.03 | 10.54 | 28 | 41572 | 2248 | 64454884 |
Syncope | 55.59 | 10.54 | 225 | 41375 | 157410 | 64299722 |
Acute kidney injury | 55.57 | 10.54 | 486 | 41114 | 448754 | 64008378 |
Blood pressure increased | 53.63 | 10.54 | 237 | 41363 | 172315 | 64284817 |
Microvillous inclusion disease | 49.66 | 10.54 | 11 | 41589 | 58 | 64457074 |
Synovitis | 48.87 | 10.54 | 4 | 41596 | 99086 | 64358046 |
Drug ineffective | 48.78 | 10.54 | 330 | 41270 | 839917 | 63617215 |
Blood pressure decreased | 48.74 | 10.54 | 144 | 41456 | 86055 | 64371077 |
Collagen disorder | 48.49 | 10.54 | 14 | 41586 | 239 | 64456893 |
Weight decreased | 47.97 | 10.54 | 332 | 41268 | 285407 | 64171725 |
Death | 47.83 | 10.54 | 156 | 41444 | 482549 | 63974583 |
Hyperuricaemia | 44.35 | 10.54 | 43 | 41557 | 10148 | 64446984 |
Device related thrombosis | 43.65 | 10.54 | 23 | 41577 | 2062 | 64455070 |
Treatment failure | 43.23 | 10.54 | 11 | 41589 | 116805 | 64340327 |
Hepatic function abnormal | 42.80 | 10.54 | 114 | 41486 | 64199 | 64392933 |
Gastrooesophageal reflux disease | 40.60 | 10.54 | 132 | 41468 | 83011 | 64374121 |
Hypokalaemia | 39.82 | 10.54 | 170 | 41430 | 121733 | 64335399 |
Maternal exposure during pregnancy | 37.52 | 10.54 | 8 | 41592 | 95876 | 64361256 |
Dizziness | 37.47 | 10.54 | 433 | 41167 | 429730 | 64027402 |
Gallbladder polyp | 37.44 | 10.54 | 16 | 41584 | 896 | 64456236 |
Enteritis | 34.90 | 10.54 | 41 | 41559 | 12036 | 64445096 |
Drug intolerance | 34.80 | 10.54 | 42 | 41558 | 187950 | 64269182 |
Hyponatraemia | 34.77 | 10.54 | 188 | 41412 | 148151 | 64308981 |
Blood pressure inadequately controlled | 33.93 | 10.54 | 28 | 41572 | 5356 | 64451776 |
Cardiac failure congestive | 33.71 | 10.54 | 170 | 41430 | 130410 | 64326722 |
Renal disorder | 33.60 | 10.54 | 72 | 41528 | 35293 | 64421839 |
Infusion related reaction | 33.45 | 10.54 | 34 | 41566 | 164433 | 64292699 |
Bradycardia | 32.72 | 10.54 | 157 | 41443 | 118062 | 64339070 |
Tropical sprue | 31.74 | 10.54 | 5 | 41595 | 0 | 64457132 |
Diverticulum | 30.42 | 10.54 | 40 | 41560 | 13158 | 64443974 |
Contraindicated product administered | 30.07 | 10.54 | 16 | 41584 | 107813 | 64349319 |
Gastritis | 29.83 | 10.54 | 77 | 41523 | 42541 | 64414591 |
Prerenal failure | 29.66 | 10.54 | 21 | 41579 | 3201 | 64453931 |
Pericarditis | 29.54 | 10.54 | 3 | 41597 | 62513 | 64394619 |
Therapeutic product effect decreased | 29.50 | 10.54 | 19 | 41581 | 115332 | 64341800 |
Product use issue | 29.03 | 10.54 | 33 | 41567 | 151682 | 64305450 |
Hyperkinetic heart syndrome | 28.67 | 10.54 | 8 | 41592 | 120 | 64457012 |
Interstitial lung disease | 28.66 | 10.54 | 132 | 41468 | 97600 | 64359532 |
Intestinal intraepithelial lymphocytes increased | 27.36 | 10.54 | 5 | 41595 | 7 | 64457125 |
Chronic gastritis | 27.27 | 10.54 | 20 | 41580 | 3220 | 64453912 |
Right atrial hypertrophy | 27.23 | 10.54 | 11 | 41589 | 534 | 64456598 |
Blood urea increased | 27.11 | 10.54 | 76 | 41524 | 44077 | 64413055 |
Chronic kidney disease | 26.53 | 10.54 | 90 | 41510 | 57829 | 64399303 |
Lower respiratory tract infection | 26.44 | 10.54 | 14 | 41586 | 94600 | 64362532 |
Drug abuse | 26.20 | 10.54 | 28 | 41572 | 132346 | 64324786 |
Decreased appetite | 26.19 | 10.54 | 287 | 41313 | 281002 | 64176130 |
Febrile neutropenia | 26.02 | 10.54 | 51 | 41549 | 187606 | 64269526 |
Exposure during pregnancy | 25.67 | 10.54 | 9 | 41591 | 77666 | 64379466 |
Systemic lupus erythematosus | 25.63 | 10.54 | 9 | 41591 | 77603 | 64379529 |
Lymphocytic infiltration | 25.24 | 10.54 | 14 | 41586 | 1390 | 64455742 |
Wound | 25.03 | 10.54 | 9 | 41591 | 76468 | 64380664 |
Hiatus hernia | 24.21 | 10.54 | 45 | 41555 | 19912 | 64437220 |
Neutropenia | 23.98 | 10.54 | 77 | 41523 | 239547 | 64217585 |
Pemphigus | 23.88 | 10.54 | 5 | 41595 | 60696 | 64396436 |
Large intestine polyp | 23.68 | 10.54 | 32 | 41568 | 10805 | 64446327 |
Product use in unapproved indication | 23.63 | 10.54 | 49 | 41551 | 176569 | 64280563 |
Pulmonary function test abnormal | 23.23 | 10.54 | 18 | 41582 | 3146 | 64453986 |
Obstruction | 22.81 | 10.54 | 18 | 41582 | 3230 | 64453902 |
Liver disorder | 22.78 | 10.54 | 81 | 41519 | 53270 | 64403862 |
Aortic dissection | 21.85 | 10.54 | 18 | 41582 | 3434 | 64453698 |
Autoimmune enteropathy | 21.00 | 10.54 | 5 | 41595 | 38 | 64457094 |
Asthenia | 20.97 | 10.54 | 390 | 41210 | 427654 | 64029478 |
Gravitational oedema | 20.44 | 10.54 | 13 | 41587 | 1659 | 64455473 |
Arthropathy | 20.35 | 10.54 | 29 | 41571 | 120938 | 64336194 |
Joint swelling | 20.32 | 10.54 | 71 | 41529 | 215311 | 64241821 |
Pain | 19.92 | 10.54 | 245 | 41355 | 553266 | 63903866 |
Haemorrhoids | 19.59 | 10.54 | 46 | 41554 | 23955 | 64433177 |
Blood creatinine increased | 19.44 | 10.54 | 152 | 41448 | 135630 | 64321502 |
Pulmonary hypoplasia | 19.43 | 10.54 | 5 | 41595 | 54 | 64457078 |
Aortic valve stenosis | 19.32 | 10.54 | 19 | 41581 | 4561 | 64452571 |
Exercise lack of | 18.98 | 10.54 | 8 | 41592 | 433 | 64456699 |
Anaplastic astrocytoma | 18.82 | 10.54 | 6 | 41594 | 145 | 64456987 |
Putamen haemorrhage | 18.81 | 10.54 | 8 | 41592 | 443 | 64456689 |
Swelling | 18.57 | 10.54 | 48 | 41552 | 160170 | 64296962 |
Enterocolitis | 18.36 | 10.54 | 30 | 41570 | 11988 | 64445144 |
Gastrointestinal erosion | 18.23 | 10.54 | 10 | 41590 | 972 | 64456160 |
Infective exacerbation of chronic obstructive airways disease | 18.18 | 10.54 | 14 | 41586 | 2424 | 64454708 |
Metabolic acidosis | 18.03 | 10.54 | 92 | 41508 | 70866 | 64386266 |
Transient aphasia | 18.02 | 10.54 | 6 | 41594 | 167 | 64456965 |
Right ventricular hypertrophy | 18 | 10.54 | 11 | 41589 | 1309 | 64455823 |
Erosive duodenitis | 17.95 | 10.54 | 12 | 41588 | 1666 | 64455466 |
Condition aggravated | 17.84 | 10.54 | 154 | 41446 | 372272 | 64084860 |
Cerebral haemorrhage | 17.25 | 10.54 | 72 | 41528 | 51018 | 64406114 |
Gluten sensitivity | 17.25 | 10.54 | 7 | 41593 | 344 | 64456788 |
Myocardial infarction | 17.20 | 10.54 | 173 | 41427 | 165648 | 64291484 |
Diabetic nephropathy | 17.14 | 10.54 | 14 | 41586 | 2640 | 64454492 |
Hypersensitivity | 17.06 | 10.54 | 67 | 41533 | 196385 | 64260747 |
Gastric cancer | 17.05 | 10.54 | 21 | 41579 | 6472 | 64450660 |
Atrial fibrillation | 17.04 | 10.54 | 177 | 41423 | 170912 | 64286220 |
Hypoalbuminaemia | 16.81 | 10.54 | 36 | 41564 | 17638 | 64439494 |
Nail disorder | 16.66 | 10.54 | 24 | 41576 | 8600 | 64448532 |
Leukocyturia | 16.46 | 10.54 | 11 | 41589 | 1527 | 64455605 |
Coronary artery occlusion | 16.45 | 10.54 | 31 | 41569 | 13860 | 64443272 |
Gout | 16.36 | 10.54 | 40 | 41560 | 21373 | 64435759 |
Hypertension | 16.26 | 10.54 | 246 | 41354 | 259015 | 64198117 |
Heart rate irregular | 15.67 | 10.54 | 46 | 41554 | 27367 | 64429765 |
Chest pain | 15.61 | 10.54 | 226 | 41374 | 235754 | 64221378 |
Rheumatoid arthritis | 15.60 | 10.54 | 54 | 41546 | 164240 | 64292892 |
Infection | 15.45 | 10.54 | 64 | 41536 | 184816 | 64272316 |
Lymphangiectasia intestinal | 15.43 | 10.54 | 3 | 41597 | 7 | 64457125 |
Renal cyst haemorrhage | 15.40 | 10.54 | 7 | 41593 | 455 | 64456677 |
Ileal ulcer | 15.30 | 10.54 | 9 | 41591 | 999 | 64456133 |
Bradyphrenia | 15.08 | 10.54 | 24 | 41576 | 9382 | 64447750 |
Rhabdomyolysis | 15.00 | 10.54 | 106 | 41494 | 91620 | 64365512 |
Musculoskeletal stiffness | 14.98 | 10.54 | 36 | 41564 | 123170 | 64333962 |
Anti-transglutaminase antibody increased | 14.89 | 10.54 | 3 | 41597 | 9 | 64457123 |
Glossodynia | 14.78 | 10.54 | 12 | 41588 | 64684 | 64392448 |
Hospitalisation | 14.77 | 10.54 | 16 | 41584 | 75191 | 64381941 |
Presyncope | 14.74 | 10.54 | 53 | 41547 | 35036 | 64422096 |
Gastritis erosive | 14.72 | 10.54 | 24 | 41576 | 9571 | 64447561 |
Encephalopathy | 14.61 | 10.54 | 10 | 41590 | 58809 | 64398323 |
Histology abnormal | 14.55 | 10.54 | 6 | 41594 | 307 | 64456825 |
Bronchial wall thickening | 14.33 | 10.54 | 11 | 41589 | 1896 | 64455236 |
Skin exfoliation | 14.18 | 10.54 | 62 | 41538 | 44823 | 64412309 |
Intentional product use issue | 14.02 | 10.54 | 25 | 41575 | 95339 | 64361793 |
Autoimmune hepatitis | 13.84 | 10.54 | 24 | 41576 | 10060 | 64447072 |
Bradykinesia | 13.77 | 10.54 | 19 | 41581 | 6541 | 64450591 |
Iron deficiency anaemia | 13.75 | 10.54 | 38 | 41562 | 21851 | 64435281 |
Coronary artery disease | 13.74 | 10.54 | 76 | 41524 | 60357 | 64396775 |
Polyp | 13.52 | 10.54 | 19 | 41581 | 6654 | 64450478 |
General physical health deterioration | 13.47 | 10.54 | 77 | 41523 | 204348 | 64252784 |
Hypocalcaemia | 13.44 | 10.54 | 58 | 41542 | 41695 | 64415437 |
Blood potassium increased | 13.36 | 10.54 | 42 | 41558 | 25938 | 64431194 |
Lymphocytosis | 13.34 | 10.54 | 14 | 41586 | 3630 | 64453502 |
Intestinal ulcer perforation | 13.22 | 10.54 | 3 | 41597 | 18 | 64457114 |
Hypomagnesaemia | 12.87 | 10.54 | 53 | 41547 | 37323 | 64419809 |
Leukopenia | 12.78 | 10.54 | 29 | 41571 | 101213 | 64355919 |
Anaemia | 12.75 | 10.54 | 327 | 41273 | 378353 | 64078779 |
Aortic valve calcification | 12.73 | 10.54 | 7 | 41593 | 683 | 64456449 |
Oedema peripheral | 12.20 | 10.54 | 197 | 41403 | 210120 | 64247012 |
Atrophy | 12.19 | 10.54 | 10 | 41590 | 1897 | 64455235 |
Normochromic normocytic anaemia | 12.03 | 10.54 | 18 | 41582 | 6672 | 64450460 |
Gastrointestinal hypermotility | 12.00 | 10.54 | 5 | 41595 | 263 | 64456869 |
Generalised oedema | 11.93 | 10.54 | 35 | 41565 | 20818 | 64436314 |
Duodenitis | 11.92 | 10.54 | 18 | 41582 | 6723 | 64450409 |
Hypovolaemia | 11.90 | 10.54 | 29 | 41571 | 15457 | 64441675 |
Disease progression | 11.86 | 10.54 | 49 | 41551 | 141631 | 64315501 |
Atrial tachycardia | 11.84 | 10.54 | 13 | 41587 | 3546 | 64453586 |
Loss of consciousness | 11.83 | 10.54 | 147 | 41453 | 148218 | 64308914 |
Drug resistance | 11.71 | 10.54 | 4 | 41596 | 35098 | 64422034 |
Mucosa vesicle | 11.69 | 10.54 | 3 | 41597 | 32 | 64457100 |
Bronchial secretion retention | 11.63 | 10.54 | 11 | 41589 | 2516 | 64454616 |
Disturbance in attention | 11.59 | 10.54 | 6 | 41594 | 41068 | 64416064 |
Acquired oesophageal web | 11.57 | 10.54 | 5 | 41595 | 288 | 64456844 |
Diabetes mellitus inadequate control | 11.45 | 10.54 | 35 | 41565 | 21286 | 64435846 |
Thalamus haemorrhage | 11.43 | 10.54 | 9 | 41591 | 1610 | 64455522 |
Duodenal ulcer haemorrhage | 11.35 | 10.54 | 17 | 41583 | 6308 | 64450824 |
Hepatitis acute | 11.30 | 10.54 | 26 | 41574 | 13363 | 64443769 |
Hypoglycaemia | 10.92 | 10.54 | 97 | 41503 | 89795 | 64367337 |
Paranasal sinus haematoma | 10.88 | 10.54 | 3 | 41597 | 43 | 64457089 |
Peripheral swelling | 10.67 | 10.54 | 85 | 41515 | 209068 | 64248064 |
Diverticulum intestinal | 10.63 | 10.54 | 18 | 41582 | 7402 | 64449730 |
Embolic stroke | 10.59 | 10.54 | 17 | 41583 | 6694 | 64450438 |
None
Source | Code | Description |
---|---|---|
ATC | C09CA08 | CARDIOVASCULAR SYSTEM AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM ANGIOTENSIN II RECEPTOR BLOCKERS (ARBs), PLAIN Angiotensin II receptor blockers (ARBs), plain |
ATC | C09DA08 | CARDIOVASCULAR SYSTEM AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM ANGIOTENSIN II RECEPTOR BLOCKERS (ARBs), COMBINATIONS Angiotensin II receptor blockers (ARBs) and diuretics |
ATC | C09DB02 | CARDIOVASCULAR SYSTEM AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM ANGIOTENSIN II RECEPTOR BLOCKERS (ARBs), COMBINATIONS Angiotensin II receptor blockers (ARBs) and calcium channel blockers |
ATC | C09DX03 | CARDIOVASCULAR SYSTEM AGENTS ACTING ON THE RENIN-ANGIOTENSIN SYSTEM ANGIOTENSIN II RECEPTOR BLOCKERS (ARBs), COMBINATIONS Angiotensin II receptor blockers (ARBs), other combinations |
FDA MoA | N0000000070 | Angiotensin 2 Receptor Antagonists |
FDA EPC | N0000175561 | Angiotensin 2 Receptor Blocker |
MeSH PA | D047228 | Angiotensin II Type 1 Receptor Blockers |
MeSH PA | D057911 | Angiotensin Receptor Antagonists |
MeSH PA | D000959 | Antihypertensive Agents |
MeSH PA | D002317 | Cardiovascular Agents |
CHEBI has role | CHEBI:35674 | antihypertensive drugs |
CHEBI has role | CHEBI:61016 | angiotensin receptor antagonists |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Hypertensive disorder | indication | 38341003 | DOID:10763 |
Chronic heart failure | off-label use | 48447003 | |
Atrial fibrillation | off-label use | 49436004 | DOID:0060224 |
Diastolic heart failure | off-label use | 418304008 | DOID:9775 |
Nondiabetic Proteinuric Nephropathy | off-label use | ||
Anuria | contraindication | 2472002 | DOID:2983 |
Hypercholesterolemia | contraindication | 13644009 | |
Hyperkalemia | contraindication | 14140009 | |
Secondary angle-closure glaucoma | contraindication | 21571006 | |
Hypovolemia | contraindication | 28560003 | |
Dehydration | contraindication | 34095006 | |
Hyperuricemia | contraindication | 35885006 | DOID:1920 |
Angioedema | contraindication | 41291007 | DOID:1558 |
Hypokalemia | contraindication | 43339004 | |
Diabetes mellitus type 2 | contraindication | 44054006 | DOID:9352 |
Low blood pressure | contraindication | 45007003 | |
Systemic lupus erythematosus | contraindication | 55464009 | DOID:9074 |
Sympathectomy | contraindication | 57071006 | |
Hepatic failure | contraindication | 59927004 | |
Hypercalcemia | contraindication | 66931009 | DOID:12678 |
Hyperparathyroidism | contraindication | 66999008 | DOID:13543 |
Hypochloremic alkalosis | contraindication | 70134007 | |
Hepatic coma | contraindication | 72836002 | DOID:12550 |
Diabetes mellitus | contraindication | 73211009 | DOID:9351 |
Chronic idiopathic constipation | contraindication | 82934008 | |
Hyponatremia | contraindication | 89627008 | |
Gout | contraindication | 90560007 | DOID:13189 |
Kidney disease | contraindication | 90708001 | DOID:557 |
Hypomagnesemia | contraindication | 190855004 | |
Acute pancreatitis | contraindication | 197456007 | DOID:2913 |
Neonatal hyperbilirubinemia | contraindication | 281610001 | |
Pregnancy, function | contraindication | 289908002 | |
Renal artery stenosis | contraindication | 302233006 | |
Azotemia | contraindication | 445009001 | |
Severe Aortic Valve Stenosis | contraindication |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 4.25 | acidic |
pKa2 | 5.76 | Basic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Type-1 angiotensin II receptor | GPCR | ANTAGONIST | IC50 | 8.10 | IUPHAR | CHEMBL | |||
Type-1 angiotensin II receptor | GPCR | IC50 | 8.09 | CHEMBL |
ID | Source |
---|---|
4021345 | VUID |
N0000179505 | NUI |
D01204 | KEGG_DRUG |
4021344 | VANDF |
4021345 | VANDF |
C0386393 | UMLSCUI |
CHEBI:31932 | CHEBI |
CHEBI:48416 | CHEBI |
OLM | PDB_CHEM_ID |
CHEMBL1200692 | ChEMBL_ID |
D000068557 | MESH_DESCRIPTOR_UI |
C437965 | MESH_SUPPLEMENTAL_RECORD_UI |
591 | IUPHAR_LIGAND_ID |
7787 | INN_ID |
144689-24-7 | SECONDARY_CAS_RN |
6M97XTV3HD | UNII |
130881 | PUBCHEM_CID |
158781 | PUBCHEM_CID |
DB00275 | DRUGBANK_ID |
118463 | RXNORM |
16642 | MMSL |
245076 | MMSL |
d04801 | MMSL |
009634 | NDDF |
009635 | NDDF |
385540001 | SNOMEDCT_US |
412259001 | SNOMEDCT_US |
412260006 | SNOMEDCT_US |
C1098320 | UMLSCUI |
CHEMBL1516 | ChEMBL_ID |
8612 | INN_ID |
8W1IQP3U10 | UNII |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0093-5002 | TABLET, FILM COATED | 40 mg | ORAL | ANDA | 26 sections |
Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0093-5003 | TABLET, FILM COATED | 40 mg | ORAL | ANDA | 26 sections |
Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0093-5004 | TABLET, FILM COATED | 40 mg | ORAL | ANDA | 26 sections |
Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0093-5005 | TABLET, FILM COATED | 20 mg | ORAL | ANDA | 26 sections |
Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0093-5006 | TABLET, FILM COATED | 40 mg | ORAL | ANDA | 26 sections |
OLMESARTAN MEDOXOMIL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0527-2425 | TABLET, FILM COATED | 5 mg | ORAL | ANDA | 31 sections |
OLMESARTAN MEDOXOMIL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0527-2425 | TABLET, FILM COATED | 5 mg | ORAL | ANDA | 31 sections |
OLMESARTAN MEDOXOMIL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0527-2426 | TABLET, FILM COATED | 20 mg | ORAL | ANDA | 31 sections |
OLMESARTAN MEDOXOMIL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0527-2426 | TABLET, FILM COATED | 20 mg | ORAL | ANDA | 31 sections |
OLMESARTAN MEDOXOMIL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0527-2427 | TABLET, FILM COATED | 40 mg | ORAL | ANDA | 31 sections |
OLMESARTAN MEDOXOMIL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0527-2427 | TABLET, FILM COATED | 40 mg | ORAL | ANDA | 31 sections |
Azor | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0713-0870 | TABLET, FILM COATED | 20 mg | ORAL | NDA | 26 sections |
Azor | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0713-0871 | TABLET, FILM COATED | 20 mg | ORAL | NDA | 26 sections |
Azor | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0713-0872 | TABLET, FILM COATED | 40 mg | ORAL | NDA | 26 sections |
Azor | HUMAN PRESCRIPTION DRUG LABEL | 2 | 0713-0873 | TABLET, FILM COATED | 40 mg | ORAL | NDA | 26 sections |
Tribenzor | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0713-0874 | TABLET, FILM COATED | 20 mg | ORAL | NDA | 28 sections |
Tribenzor | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0713-0875 | TABLET, FILM COATED | 40 mg | ORAL | NDA | 28 sections |
Tribenzor | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0713-0876 | TABLET, FILM COATED | 40 mg | ORAL | NDA | 28 sections |
Tribenzor | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0713-0877 | TABLET, FILM COATED | 40 mg | ORAL | NDA | 28 sections |
Tribenzor | HUMAN PRESCRIPTION DRUG LABEL | 3 | 0713-0878 | TABLET, FILM COATED | 40 mg | ORAL | NDA | 28 sections |
Olmesartan Medoxomil | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-248 | TABLET | 5 mg | ORAL | ANDA | 21 sections |
Olmesartan Medoxomil | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-248 | TABLET | 5 mg | ORAL | ANDA | 21 sections |
Olmesartan Medoxomil | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-249 | TABLET | 20 mg | ORAL | ANDA | 21 sections |
Olmesartan Medoxomil | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-249 | TABLET | 20 mg | ORAL | ANDA | 21 sections |
Olmesartan Medoxomil | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-250 | TABLET | 40 mg | ORAL | ANDA | 21 sections |
Olmesartan Medoxomil | HUMAN PRESCRIPTION DRUG LABEL | 1 | 13668-250 | TABLET | 40 mg | ORAL | ANDA | 21 sections |
OLMESARTAN MEDOXOMIL AND HYDROCHLOROTHIAZIDE | HUMAN PRESCRIPTION DRUG LABEL | 2 | 13668-251 | TABLET | 20 mg | ORAL | ANDA | 20 sections |
OLMESARTAN MEDOXOMIL AND HYDROCHLOROTHIAZIDE | HUMAN PRESCRIPTION DRUG LABEL | 2 | 13668-251 | TABLET | 20 mg | ORAL | ANDA | 20 sections |
OLMESARTAN MEDOXOMIL AND HYDROCHLOROTHIAZIDE | HUMAN PRESCRIPTION DRUG LABEL | 2 | 13668-252 | TABLET | 40 mg | ORAL | ANDA | 20 sections |
OLMESARTAN MEDOXOMIL AND HYDROCHLOROTHIAZIDE | HUMAN PRESCRIPTION DRUG LABEL | 2 | 13668-252 | TABLET | 40 mg | ORAL | ANDA | 20 sections |