nifurtoinol 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
5-nitrofuran derivatives 1930 1088-92-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • nifurtoinol
  • hydroxymethylnitrofurantoin
  • urfadine
  • Molecular weight: 268.19
  • Formula: C9H8N4O6
  • CLOGP: -0.78
  • LIPINSKI: 0
  • HAC: 10
  • HDO: 1
  • TPSA: 132.17
  • ALOGS: -2.69
  • ROTB: 4

Drug dosage:

DoseUnitRoute
0.16 g O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC J01XE02 ANTIINFECTIVES FOR SYSTEMIC USE
ANTIBACTERIALS FOR SYSTEMIC USE
OTHER ANTIBACTERIALS
Nitrofuran derivatives
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000892 Anti-Infective Agents, Urinary
CHEBI has role CHEBI:35441 antiinfective agents
CHEBI has role CHEBI:36047 antibacterial drugs
CHEBI has role CHEBI:50908 agente hepatotoxico

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Urinary tract infectious disease indication 68566005




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 0.0 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07243 KEGG_DRUG
C3266849 UMLSCUI
CHEBI:88255 CHEBI
CHEMBL1697763 ChEMBL_ID
DB13730 DRUGBANK_ID
C002848 MESH_SUPPLEMENTAL_RECORD_UI
9571062 PUBCHEM_CID
12346 IUPHAR_LIGAND_ID
3997 INN_ID
980688H13O UNII
005814 NDDF
713437001 SNOMEDCT_US

Pharmaceutical products:

None