Stem definition | Drug id | CAS RN |
---|---|---|
calcium channel blockers, nifedipine derivatives | 1922 | 21829-25-4 |
Dose | Unit | Route |
---|---|---|
30 | mg | O |
30 | mg | P |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 2 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 0.01 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 0.01 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 3.71 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 50 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Vd (Volume of distribution) | 0.79 L/kg | Lombardo F, Berellini G, Obach RS |
CL (Clearance) | 7.30 mL/min/kg | Lombardo F, Berellini G, Obach RS |
fu (Fraction unbound in plasma) | 0.04 % | Lombardo F, Berellini G, Obach RS |
t_half (Half-life) | 1.90 hours | Lombardo F, Berellini G, Obach RS |
Date | Agency | Company | Orphan |
---|---|---|---|
Dec. 31, 1981 | FDA | PFIZER |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Premature delivery | 534.83 | 10.03 | 342 | 59389 | 26718 | 56205618 |
Exposure during pregnancy | 296.28 | 10.03 | 524 | 59207 | 135818 | 56096518 |
Premature baby | 259.29 | 10.03 | 192 | 59539 | 19013 | 56213323 |
Pre-eclampsia | 184.48 | 10.03 | 114 | 59617 | 8372 | 56223964 |
Low birth weight baby | 172.51 | 10.03 | 98 | 59633 | 6160 | 56226176 |
Foetal exposure during pregnancy | 161.07 | 10.03 | 189 | 59542 | 33634 | 56198702 |
Pemphigus | 128.88 | 10.03 | 10 | 59721 | 157202 | 56075134 |
Alopecia | 125.87 | 10.03 | 78 | 59653 | 293380 | 55938956 |
Hypertension | 119.18 | 10.03 | 544 | 59187 | 243734 | 55988602 |
Glossodynia | 113.70 | 10.03 | 14 | 59717 | 152444 | 56079892 |
Blood pressure inadequately controlled | 109.20 | 10.03 | 65 | 59666 | 4459 | 56227877 |
Premature labour | 97.59 | 10.03 | 89 | 59642 | 11793 | 56220543 |
Rheumatoid arthritis | 91.11 | 10.03 | 167 | 59564 | 382437 | 55849899 |
Renal impairment | 87.03 | 10.03 | 234 | 59497 | 80479 | 56151857 |
Systemic lupus erythematosus | 85.64 | 10.03 | 42 | 59689 | 180036 | 56052300 |
Hypotension | 85.39 | 10.03 | 505 | 59226 | 250003 | 55982333 |
Maternal exposure during pregnancy | 83.50 | 10.03 | 410 | 59321 | 189143 | 56043193 |
Blood pressure increased | 82.72 | 10.03 | 339 | 59392 | 144837 | 56087499 |
Arthropathy | 82.03 | 10.03 | 56 | 59675 | 200219 | 56032117 |
Caesarean section | 80.07 | 10.03 | 92 | 59639 | 15999 | 56216337 |
Neovascularisation | 79.97 | 10.03 | 33 | 59698 | 1016 | 56231320 |
Pericarditis | 78.80 | 10.03 | 11 | 59720 | 108912 | 56123424 |
Oedema peripheral | 76.54 | 10.03 | 372 | 59359 | 170882 | 56061454 |
Contraindicated product administered | 76.41 | 10.03 | 52 | 59679 | 186234 | 56046102 |
Therapeutic product effect decreased | 75.44 | 10.03 | 43 | 59688 | 169409 | 56062927 |
Wound | 74.60 | 10.03 | 27 | 59704 | 138777 | 56093559 |
Discomfort | 70.58 | 10.03 | 31 | 59700 | 141730 | 56090606 |
Infusion related reaction | 66.68 | 10.03 | 74 | 59657 | 208857 | 56023479 |
Foetal growth restriction | 63.89 | 10.03 | 56 | 59675 | 7043 | 56225293 |
Rheumatoid factor positive | 60.73 | 10.03 | 3 | 59728 | 69057 | 56163279 |
Proteinuria | 58.14 | 10.03 | 82 | 59649 | 17488 | 56214848 |
Helicobacter infection | 56.42 | 10.03 | 6 | 59725 | 73262 | 56159074 |
Joint swelling | 56.02 | 10.03 | 142 | 59589 | 289658 | 55942678 |
Cardiac failure congestive | 54.06 | 10.03 | 210 | 59521 | 87510 | 56144826 |
Drug ineffective | 52.97 | 10.03 | 674 | 59057 | 918315 | 55314021 |
Hypersensitivity | 52.41 | 10.03 | 122 | 59609 | 256286 | 55976050 |
Synovitis | 51.60 | 10.03 | 57 | 59674 | 161248 | 56071088 |
Scleroderma | 50.21 | 10.03 | 42 | 59689 | 4959 | 56227377 |
Pulmonary oedema | 49.89 | 10.03 | 143 | 59588 | 51000 | 56181336 |
Blood pressure diastolic abnormal | 48.97 | 10.03 | 61 | 59670 | 11537 | 56220799 |
Cerebral infarction | 48.11 | 10.03 | 86 | 59645 | 22419 | 56209917 |
Dyspnoea exertional | 47.73 | 10.03 | 147 | 59584 | 54542 | 56177794 |
Anuria | 46.72 | 10.03 | 60 | 59671 | 11700 | 56220636 |
Primary hyperaldosteronism | 46.11 | 10.03 | 11 | 59720 | 47 | 56232289 |
Rash | 45.72 | 10.03 | 321 | 59410 | 492726 | 55739610 |
Blood pressure systolic abnormal | 45.47 | 10.03 | 54 | 59677 | 9723 | 56222613 |
Heart rate decreased | 45.36 | 10.03 | 119 | 59612 | 40308 | 56192028 |
Acute pulmonary oedema | 43.94 | 10.03 | 47 | 59684 | 7550 | 56224786 |
Abdominal discomfort | 43.34 | 10.03 | 150 | 59581 | 277124 | 55955212 |
Paradoxical drug reaction | 42.37 | 10.03 | 34 | 59697 | 3786 | 56228550 |
Hepatic enzyme increased | 42.32 | 10.03 | 73 | 59658 | 171311 | 56061025 |
Oligohydramnios | 41.77 | 10.03 | 41 | 59690 | 5953 | 56226383 |
Intestinal angioedema | 41.70 | 10.03 | 18 | 59713 | 621 | 56231715 |
Treatment failure | 41.69 | 10.03 | 73 | 59658 | 170319 | 56062017 |
Pain | 41.27 | 10.03 | 478 | 59253 | 662706 | 55569630 |
Drug intolerance | 40.22 | 10.03 | 145 | 59586 | 264673 | 55967663 |
Drug dispensed to wrong patient | 39.97 | 10.03 | 13 | 59718 | 199 | 56232137 |
Aplastic anaemia | 39.38 | 10.03 | 48 | 59683 | 8880 | 56223456 |
Transfusion | 38.79 | 10.03 | 59 | 59672 | 13461 | 56218875 |
Sinusitis | 38.77 | 10.03 | 96 | 59635 | 197485 | 56034851 |
Blood aldosterone increased | 38.55 | 10.03 | 12 | 59719 | 158 | 56232178 |
Lower respiratory tract infection | 38.45 | 10.03 | 39 | 59692 | 114755 | 56117581 |
Rectal prolapse | 37.77 | 10.03 | 24 | 59707 | 1850 | 56230486 |
Eclampsia | 37.38 | 10.03 | 14 | 59717 | 331 | 56232005 |
Uraemic encephalopathy | 37.31 | 10.03 | 13 | 59718 | 248 | 56232088 |
Drug abuse | 36.56 | 10.03 | 13 | 59718 | 67597 | 56164739 |
Hypergammaglobulinaemia | 36.43 | 10.03 | 15 | 59716 | 459 | 56231877 |
Bradycardia | 36.34 | 10.03 | 155 | 59576 | 67349 | 56164987 |
Dyspnoea | 35.74 | 10.03 | 851 | 58880 | 591726 | 55640610 |
Blood creatinine increased | 35.63 | 10.03 | 174 | 59557 | 80017 | 56152319 |
Polyhydramnios | 35.12 | 10.03 | 24 | 59707 | 2091 | 56230245 |
Bladder prolapse | 34.46 | 10.03 | 23 | 59708 | 1928 | 56230408 |
Swelling | 33.36 | 10.03 | 136 | 59595 | 239635 | 55992701 |
Impaired healing | 33.29 | 10.03 | 26 | 59705 | 86815 | 56145521 |
Dialysis | 33.17 | 10.03 | 46 | 59685 | 9656 | 56222680 |
Hypertensive crisis | 33.08 | 10.03 | 56 | 59675 | 13980 | 56218356 |
Foetal death | 32.84 | 10.03 | 43 | 59688 | 8544 | 56223792 |
Phaeochromocytoma | 32.38 | 10.03 | 14 | 59717 | 485 | 56231851 |
Blood pressure systolic increased | 32.19 | 10.03 | 106 | 59625 | 40730 | 56191606 |
Cardiac failure | 32.19 | 10.03 | 172 | 59559 | 81921 | 56150415 |
Premature separation of placenta | 31.69 | 10.03 | 21 | 59710 | 1739 | 56230597 |
Renal artery stenosis | 31.02 | 10.03 | 21 | 59710 | 1802 | 56230534 |
Neutropenia | 30.91 | 10.03 | 77 | 59654 | 158090 | 56074246 |
Knee arthroplasty | 30.78 | 10.03 | 5 | 59726 | 44254 | 56188082 |
Product complaint | 30.51 | 10.03 | 49 | 59682 | 11711 | 56220625 |
Psoriasis | 30.46 | 10.03 | 32 | 59699 | 92660 | 56139676 |
Respiratory tract inflammation | 30.34 | 10.03 | 14 | 59717 | 567 | 56231769 |
Drug ineffective for unapproved indication | 30.23 | 10.03 | 77 | 59654 | 25616 | 56206720 |
Product use issue | 30.16 | 10.03 | 99 | 59632 | 185942 | 56046394 |
Nodular regenerative hyperplasia | 30.10 | 10.03 | 13 | 59718 | 449 | 56231887 |
Injection site erythema | 29.92 | 10.03 | 23 | 59708 | 77425 | 56154911 |
Neonatal respiratory distress syndrome | 29.46 | 10.03 | 24 | 59707 | 2730 | 56229606 |
Superimposed pre-eclampsia | 29.25 | 10.03 | 5 | 59726 | 0 | 56232336 |
CD30 expression | 29.14 | 10.03 | 7 | 59724 | 31 | 56232305 |
Angina unstable | 29.00 | 10.03 | 36 | 59695 | 6785 | 56225551 |
Infection | 28.83 | 10.03 | 112 | 59619 | 200094 | 56032242 |
Hypervolaemia | 28.78 | 10.03 | 77 | 59654 | 26381 | 56205955 |
Wrist deformity | 28.20 | 10.03 | 20 | 59711 | 1850 | 56230486 |
Fatigue | 27.74 | 10.03 | 632 | 59099 | 787920 | 55444416 |
Peripartum cardiomyopathy | 27.30 | 10.03 | 9 | 59722 | 144 | 56232192 |
Hyperkalaemia | 26.76 | 10.03 | 116 | 59615 | 50749 | 56181587 |
Product residue present | 26.52 | 10.03 | 26 | 59705 | 3769 | 56228567 |
Cerebrovascular accident | 26.30 | 10.03 | 188 | 59543 | 99082 | 56133254 |
Tubulointerstitial nephritis | 26.25 | 10.03 | 56 | 59675 | 16609 | 56215727 |
Blood pressure decreased | 26.13 | 10.03 | 128 | 59603 | 58922 | 56173414 |
Renin decreased | 26.08 | 10.03 | 8 | 59723 | 100 | 56232236 |
Patent ductus arteriosus | 25.64 | 10.03 | 26 | 59705 | 3925 | 56228411 |
Irritable bowel syndrome | 25.60 | 10.03 | 21 | 59710 | 68437 | 56163899 |
Pulmonary hypertension | 25.43 | 10.03 | 90 | 59641 | 35854 | 56196482 |
Electrocardiogram PR prolongation | 25.08 | 10.03 | 13 | 59718 | 680 | 56231656 |
Thermal burn | 25.02 | 10.03 | 30 | 59701 | 5455 | 56226881 |
Blood pressure diastolic decreased | 24.94 | 10.03 | 60 | 59671 | 19263 | 56213073 |
Psoriatic arthropathy | 24.94 | 10.03 | 25 | 59706 | 73983 | 56158353 |
Foetal distress syndrome | 24.71 | 10.03 | 16 | 59715 | 1274 | 56231062 |
Foetal exposure timing unspecified | 24.51 | 10.03 | 9 | 59722 | 201 | 56232135 |
Blood urea increased | 24.41 | 10.03 | 69 | 59662 | 24404 | 56207932 |
Blood pressure fluctuation | 24.34 | 10.03 | 96 | 59635 | 40264 | 56192072 |
Renal failure | 24.11 | 10.03 | 200 | 59531 | 110300 | 56122036 |
Cognitive disorder | 24.03 | 10.03 | 11 | 59720 | 49122 | 56183214 |
Peripheral vascular disorder | 23.99 | 10.03 | 30 | 59701 | 5695 | 56226641 |
Pain in jaw | 23.96 | 10.03 | 95 | 59636 | 39941 | 56192395 |
Aortic dissection | 23.77 | 10.03 | 18 | 59713 | 1841 | 56230495 |
Blister | 23.70 | 10.03 | 50 | 59681 | 108837 | 56123499 |
Infrequent bowel movements | 23.40 | 10.03 | 15 | 59716 | 1174 | 56231162 |
Oedema | 23.38 | 10.03 | 158 | 59573 | 81762 | 56150574 |
Injection site reaction | 22.98 | 10.03 | 14 | 59717 | 53233 | 56179103 |
Finger amputation | 22.29 | 10.03 | 11 | 59720 | 518 | 56231818 |
Preterm premature rupture of membranes | 22.05 | 10.03 | 15 | 59716 | 1297 | 56231039 |
Adverse drug reaction | 21.95 | 10.03 | 22 | 59709 | 65110 | 56167226 |
Maternal condition affecting foetus | 21.94 | 10.03 | 8 | 59723 | 175 | 56232161 |
Palpitations | 21.53 | 10.03 | 180 | 59551 | 99492 | 56132844 |
Diabetic nephropathy | 21.52 | 10.03 | 15 | 59716 | 1349 | 56230987 |
HELLP syndrome | 21.43 | 10.03 | 13 | 59718 | 923 | 56231413 |
Fibromyalgia | 21.41 | 10.03 | 19 | 59712 | 59584 | 56172752 |
Injection site inflammation | 21.30 | 10.03 | 22 | 59709 | 3394 | 56228942 |
Stomatitis | 21.19 | 10.03 | 62 | 59669 | 120748 | 56111588 |
Endometritis | 20.72 | 10.03 | 13 | 59718 | 980 | 56231356 |
Left ventricular hypertrophy | 20.70 | 10.03 | 26 | 59705 | 4958 | 56227378 |
Stillbirth | 20.55 | 10.03 | 29 | 59702 | 6185 | 56226151 |
Respiratory distress | 20.47 | 10.03 | 77 | 59654 | 31590 | 56200746 |
Shock | 20.45 | 10.03 | 60 | 59671 | 21668 | 56210668 |
Fluid retention | 20.31 | 10.03 | 112 | 59619 | 53966 | 56178370 |
Hip arthroplasty | 19.92 | 10.03 | 8 | 59723 | 38615 | 56193721 |
Renal hypoplasia | 19.84 | 10.03 | 5 | 59726 | 28 | 56232308 |
Hepatic rupture | 19.69 | 10.03 | 5 | 59726 | 29 | 56232307 |
Nephrogenic systemic fibrosis | 19.68 | 10.03 | 24 | 59707 | 4441 | 56227895 |
Drug titration error | 19.63 | 10.03 | 11 | 59720 | 673 | 56231663 |
Urticaria | 19.52 | 10.03 | 83 | 59648 | 144593 | 56087743 |
Porphyria acute | 19.16 | 10.03 | 12 | 59719 | 902 | 56231434 |
Hypovolaemic shock | 19.16 | 10.03 | 26 | 59705 | 5347 | 56226989 |
Bradycardia foetal | 18.72 | 10.03 | 9 | 59722 | 400 | 56231936 |
Myocardial infarction | 18.63 | 10.03 | 165 | 59566 | 92705 | 56139631 |
Hepatic function abnormal | 18.32 | 10.03 | 79 | 59652 | 34479 | 56197857 |
BRASH syndrome | 18.19 | 10.03 | 8 | 59723 | 289 | 56232047 |
Barotrauma | 18.14 | 10.03 | 7 | 59724 | 180 | 56232156 |
Drug interaction | 18.11 | 10.03 | 318 | 59413 | 209437 | 56022899 |
Atrial septal defect | 18.11 | 10.03 | 28 | 59703 | 6478 | 56225858 |
Frostbite | 18.09 | 10.03 | 6 | 59725 | 98 | 56232238 |
Urine output decreased | 17.89 | 10.03 | 37 | 59694 | 10740 | 56221596 |
Haemoglobin decreased | 17.75 | 10.03 | 219 | 59512 | 133918 | 56098418 |
Foetal exposure during delivery | 17.69 | 10.03 | 5 | 59726 | 46 | 56232290 |
Vascular resistance systemic increased | 17.55 | 10.03 | 3 | 59728 | 0 | 56232336 |
Tocolysis | 17.55 | 10.03 | 3 | 59728 | 0 | 56232336 |
Therapeutic product effect incomplete | 17.47 | 10.03 | 56 | 59675 | 105975 | 56126361 |
Vitamin D decreased | 17.26 | 10.03 | 33 | 59698 | 9050 | 56223286 |
Hypertensive emergency | 17.14 | 10.03 | 14 | 59717 | 1599 | 56230737 |
Oral herpes | 16.78 | 10.03 | 58 | 59673 | 22832 | 56209504 |
Acute myocardial infarction | 16.51 | 10.03 | 70 | 59661 | 30323 | 56202013 |
Multiple sclerosis relapse | 16.51 | 10.03 | 14 | 59717 | 44889 | 56187447 |
Chronic kidney disease | 16.40 | 10.03 | 88 | 59643 | 41968 | 56190368 |
Intentional product use issue | 16.20 | 10.03 | 53 | 59678 | 99680 | 56132656 |
Product substitution error | 16.09 | 10.03 | 4 | 59727 | 21 | 56232315 |
Atrioventricular block first degree | 15.95 | 10.03 | 27 | 59704 | 6738 | 56225598 |
Febrile neutropenia | 15.85 | 10.03 | 58 | 59673 | 105487 | 56126849 |
Laboratory test interference | 15.85 | 10.03 | 9 | 59722 | 565 | 56231771 |
Hyperuricaemia | 15.79 | 10.03 | 23 | 59708 | 5050 | 56227286 |
Therapy partial responder | 15.68 | 10.03 | 29 | 59702 | 7756 | 56224580 |
Angina pectoris | 15.64 | 10.03 | 65 | 59666 | 27911 | 56204425 |
Pseudolymphoma | 15.59 | 10.03 | 9 | 59722 | 583 | 56231753 |
Extrapyramidal disorder | 15.55 | 10.03 | 38 | 59693 | 12318 | 56220018 |
Injection site pruritus | 15.51 | 10.03 | 13 | 59718 | 41918 | 56190418 |
Coronary artery disease | 15.26 | 10.03 | 69 | 59662 | 30727 | 56201609 |
Cardiomegaly | 15.05 | 10.03 | 45 | 59686 | 16422 | 56215914 |
Scleroderma renal crisis | 15.02 | 10.03 | 7 | 59724 | 290 | 56232046 |
Ileal ulcer | 15.01 | 10.03 | 8 | 59723 | 443 | 56231893 |
Gestational hypertension | 14.69 | 10.03 | 15 | 59716 | 2284 | 56230052 |
Metabolic acidosis | 14.67 | 10.03 | 83 | 59648 | 40371 | 56191965 |
Renal atrophy | 14.61 | 10.03 | 12 | 59719 | 1381 | 56230955 |
Foetal heart rate deceleration abnormality | 14.59 | 10.03 | 8 | 59723 | 469 | 56231867 |
Skin induration | 14.58 | 10.03 | 17 | 59714 | 3001 | 56229335 |
Foetal hypokinesia | 14.45 | 10.03 | 8 | 59723 | 478 | 56231858 |
Malignant hypertension | 14.43 | 10.03 | 11 | 59720 | 1137 | 56231199 |
Myocardial depression | 14.40 | 10.03 | 8 | 59723 | 481 | 56231855 |
Pulmonary arterial hypertension | 14.37 | 10.03 | 61 | 59670 | 26442 | 56205894 |
Respiratory failure | 14.26 | 10.03 | 159 | 59572 | 94903 | 56137433 |
Umbilical cord vascular disorder | 14.18 | 10.03 | 5 | 59726 | 99 | 56232237 |
Wrong technique in product usage process | 14.14 | 10.03 | 25 | 59706 | 58143 | 56174193 |
Altered state of consciousness | 14.08 | 10.03 | 55 | 59676 | 22966 | 56209370 |
Aortic valve incompetence | 14.04 | 10.03 | 23 | 59708 | 5589 | 56226747 |
Transferrin decreased | 14.04 | 10.03 | 6 | 59725 | 202 | 56232134 |
Skin hypertrophy | 13.74 | 10.03 | 17 | 59714 | 3193 | 56229143 |
Ventricular hypertrophy | 13.62 | 10.03 | 17 | 59714 | 3221 | 56229115 |
Oxygen saturation decreased | 13.62 | 10.03 | 136 | 59595 | 78931 | 56153405 |
Hypoaesthesia teeth | 13.51 | 10.03 | 4 | 59727 | 44 | 56232292 |
Human chorionic gonadotropin positive | 13.51 | 10.03 | 4 | 59727 | 44 | 56232292 |
Type 2 diabetes mellitus | 13.44 | 10.03 | 18 | 59713 | 46844 | 56185492 |
Dermatophytosis of nail | 13.27 | 10.03 | 4 | 59727 | 47 | 56232289 |
Gastrointestinal disorder | 13.22 | 10.03 | 68 | 59663 | 112634 | 56119702 |
Contusion | 13.16 | 10.03 | 81 | 59650 | 128349 | 56103987 |
Cortisol increased | 13.15 | 10.03 | 7 | 59724 | 387 | 56231949 |
Blood lactate dehydrogenase increased | 13.14 | 10.03 | 50 | 59681 | 20625 | 56211711 |
Liver injury | 13.13 | 10.03 | 15 | 59716 | 41833 | 56190503 |
Hypoproteinaemia | 13.09 | 10.03 | 13 | 59718 | 1915 | 56230421 |
Haemoperitoneum | 13.02 | 10.03 | 15 | 59716 | 2615 | 56229721 |
Microvillous inclusion disease | 12.94 | 10.03 | 3 | 59728 | 11 | 56232325 |
Platelet count decreased | 12.93 | 10.03 | 171 | 59560 | 106212 | 56126124 |
Transient ischaemic attack | 12.91 | 10.03 | 70 | 59661 | 33507 | 56198829 |
Spinal cord infarction | 12.89 | 10.03 | 6 | 59725 | 248 | 56232088 |
Accidental exposure to product | 12.88 | 10.03 | 5 | 59726 | 24642 | 56207694 |
Cervical incompetence | 12.84 | 10.03 | 8 | 59723 | 596 | 56231740 |
Neonatal hyponatraemia | 12.76 | 10.03 | 4 | 59727 | 54 | 56232282 |
Premature rupture of membranes | 12.56 | 10.03 | 20 | 59711 | 4745 | 56227591 |
Joint contracture | 12.53 | 10.03 | 12 | 59719 | 1690 | 56230646 |
Hypoxia | 12.53 | 10.03 | 99 | 59632 | 53798 | 56178538 |
Jaundice neonatal | 12.48 | 10.03 | 9 | 59722 | 854 | 56231482 |
Small for dates baby | 12.46 | 10.03 | 17 | 59714 | 3513 | 56228823 |
Feeling cold | 12.46 | 10.03 | 50 | 59681 | 21137 | 56211199 |
Blood corticotrophin decreased | 12.45 | 10.03 | 6 | 59725 | 268 | 56232068 |
Skin tightness | 12.41 | 10.03 | 18 | 59713 | 3937 | 56228399 |
Cardiac arrest | 12.32 | 10.03 | 143 | 59588 | 86171 | 56146165 |
Muscle spasticity | 12.32 | 10.03 | 3 | 59728 | 19957 | 56212379 |
Antibody test positive | 12.26 | 10.03 | 14 | 59717 | 2417 | 56229919 |
Pancreatitis haemorrhagic | 12.23 | 10.03 | 7 | 59724 | 446 | 56231890 |
Ill-defined disorder | 12.14 | 10.03 | 35 | 59696 | 68508 | 56163828 |
Heliotrope rash | 12.05 | 10.03 | 5 | 59726 | 156 | 56232180 |
Hypoglycaemia neonatal | 11.96 | 10.03 | 9 | 59722 | 912 | 56231424 |
Neuromuscular blockade | 11.92 | 10.03 | 6 | 59725 | 295 | 56232041 |
Systemic scleroderma | 11.76 | 10.03 | 9 | 59722 | 935 | 56231401 |
Amniotic cavity infection | 11.75 | 10.03 | 10 | 59721 | 1208 | 56231128 |
Hospitalisation | 11.50 | 10.03 | 126 | 59605 | 74874 | 56157462 |
Arrhythmia | 11.44 | 10.03 | 70 | 59661 | 35013 | 56197323 |
Haemodialysis | 11.44 | 10.03 | 27 | 59704 | 8564 | 56223772 |
Injection site pain | 11.42 | 10.03 | 75 | 59656 | 117043 | 56115293 |
Wheezing | 11.42 | 10.03 | 41 | 59690 | 74985 | 56157351 |
Ductus arteriosus premature closure | 11.40 | 10.03 | 6 | 59725 | 324 | 56232012 |
Stevens-Johnson syndrome | 11.40 | 10.03 | 51 | 59680 | 22612 | 56209724 |
Carotid artery disease | 11.38 | 10.03 | 11 | 59720 | 1567 | 56230769 |
Sinus bradycardia | 11.37 | 10.03 | 36 | 59695 | 13550 | 56218786 |
Macular degeneration | 11.37 | 10.03 | 3 | 59728 | 18905 | 56213431 |
Suicidal ideation | 11.35 | 10.03 | 28 | 59703 | 57714 | 56174622 |
Brain natriuretic peptide increased | 11.33 | 10.03 | 19 | 59712 | 4707 | 56227629 |
Joint range of motion decreased | 11.23 | 10.03 | 55 | 59676 | 25310 | 56207026 |
Glomerulonephritis membranoproliferative | 11.21 | 10.03 | 5 | 59726 | 187 | 56232149 |
Weight increased | 11.13 | 10.03 | 174 | 59557 | 229529 | 56002807 |
Nephrotic syndrome | 11 | 10.03 | 20 | 59711 | 5280 | 56227056 |
Platelet transfusion | 10.94 | 10.03 | 8 | 59723 | 776 | 56231560 |
Haemodialysis complication | 10.94 | 10.03 | 5 | 59726 | 198 | 56232138 |
Poikiloderma | 10.94 | 10.03 | 5 | 59726 | 198 | 56232138 |
Lacunar infarction | 10.88 | 10.03 | 15 | 59716 | 3130 | 56229206 |
Arthralgia | 10.84 | 10.03 | 429 | 59302 | 501240 | 55731096 |
Intestinal pseudo-obstruction | 10.82 | 10.03 | 8 | 59723 | 789 | 56231547 |
Peripheral ischaemia | 10.77 | 10.03 | 18 | 59713 | 4445 | 56227891 |
Foot deformity | 10.65 | 10.03 | 6 | 59725 | 23819 | 56208517 |
Mallory-Weiss syndrome | 10.63 | 10.03 | 10 | 59721 | 1377 | 56230959 |
Hypoperfusion | 10.62 | 10.03 | 10 | 59721 | 1380 | 56230956 |
Device expulsion | 10.59 | 10.03 | 10 | 59721 | 30439 | 56201897 |
Hypertensive encephalopathy | 10.52 | 10.03 | 7 | 59724 | 584 | 56231752 |
Nasopharyngitis | 10.50 | 10.03 | 168 | 59563 | 220791 | 56011545 |
Mental status changes | 10.50 | 10.03 | 72 | 59659 | 37429 | 56194907 |
Hyperplasia adrenal | 10.48 | 10.03 | 3 | 59728 | 29 | 56232307 |
Temperature intolerance | 10.41 | 10.03 | 25 | 59706 | 8015 | 56224321 |
Arteriovenous fistula operation | 10.36 | 10.03 | 5 | 59726 | 224 | 56232112 |
Pyuria | 10.34 | 10.03 | 11 | 59720 | 1756 | 56230580 |
Congenital hypothyroidism | 10.32 | 10.03 | 5 | 59726 | 226 | 56232110 |
Large intestine benign neoplasm | 10.25 | 10.03 | 4 | 59727 | 106 | 56232230 |
Right atrial enlargement | 10.25 | 10.03 | 4 | 59727 | 106 | 56232230 |
Pulmonary embolism | 10.24 | 10.03 | 69 | 59662 | 107055 | 56125281 |
End stage renal disease | 10.16 | 10.03 | 21 | 59710 | 6090 | 56226246 |
Exposure via breast milk | 10.11 | 10.03 | 11 | 59720 | 1801 | 56230535 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Premature baby | 168.50 | 10.52 | 158 | 40558 | 17908 | 31638720 |
Foetal exposure during pregnancy | 135.30 | 10.52 | 211 | 40505 | 40665 | 31615963 |
Low birth weight baby | 104.22 | 10.52 | 80 | 40636 | 6890 | 31649738 |
Photodermatosis | 100.88 | 10.52 | 34 | 40682 | 477 | 31656151 |
Solar lentigo | 94.17 | 10.52 | 32 | 40684 | 461 | 31656167 |
Dysplastic naevus | 90.88 | 10.52 | 31 | 40685 | 452 | 31656176 |
Off label use | 73.36 | 10.52 | 217 | 40499 | 347057 | 31309571 |
Polydactyly | 69.82 | 10.52 | 33 | 40683 | 1161 | 31655467 |
Hypertension | 68.07 | 10.52 | 335 | 40381 | 127765 | 31528863 |
Gingival hypertrophy | 65.73 | 10.52 | 36 | 40680 | 1734 | 31654894 |
Bradycardia | 63.75 | 10.52 | 215 | 40501 | 69112 | 31587516 |
Foetal growth restriction | 61.93 | 10.52 | 46 | 40670 | 3769 | 31652859 |
Drug abuse | 61.82 | 10.52 | 18 | 40698 | 87740 | 31568888 |
Cerebral infarction | 57.07 | 10.52 | 112 | 40604 | 25865 | 31630763 |
Renal impairment | 54.06 | 10.52 | 237 | 40479 | 86112 | 31570516 |
Drug ineffective | 50.05 | 10.52 | 301 | 40415 | 395272 | 31261356 |
Completed suicide | 48.32 | 10.52 | 239 | 40477 | 91275 | 31565353 |
Hyperkalaemia | 47.64 | 10.52 | 186 | 40530 | 64165 | 31592463 |
Blood creatinine increased | 45.87 | 10.52 | 231 | 40485 | 88847 | 31567781 |
Kidney transplant rejection | 44.87 | 10.52 | 51 | 40665 | 7231 | 31649397 |
Atrioventricular septal defect | 44.47 | 10.52 | 15 | 40701 | 211 | 31656417 |
Blood urea increased | 44.24 | 10.52 | 108 | 40608 | 28904 | 31627724 |
Bezoar | 43.79 | 10.52 | 22 | 40694 | 886 | 31655742 |
Dandy-Walker syndrome | 41.50 | 10.52 | 14 | 40702 | 197 | 31656431 |
Trisomy 21 | 37.20 | 10.52 | 17 | 40699 | 553 | 31656075 |
Pulmonary hypertension | 36.49 | 10.52 | 80 | 40636 | 19961 | 31636667 |
Cardiac failure congestive | 36.14 | 10.52 | 199 | 40517 | 79188 | 31577440 |
Protein urine present | 34.72 | 10.52 | 37 | 40679 | 4883 | 31651745 |
Shock | 34.21 | 10.52 | 84 | 40632 | 22561 | 31634067 |
Actinic keratosis | 34.14 | 10.52 | 34 | 40682 | 4145 | 31652483 |
Neutropenia | 33.81 | 10.52 | 82 | 40634 | 140282 | 31516346 |
Oesophageal obstruction | 33.29 | 10.52 | 15 | 40701 | 472 | 31656156 |
Neurodevelopmental disorder | 32.10 | 10.52 | 14 | 40702 | 407 | 31656221 |
Macrocephaly | 30.34 | 10.52 | 14 | 40702 | 466 | 31656162 |
Phospholipidosis | 29.76 | 10.52 | 8 | 40708 | 48 | 31656580 |
Aplastic anaemia | 29.71 | 10.52 | 47 | 40669 | 9156 | 31647472 |
Congenital central nervous system anomaly | 28.94 | 10.52 | 14 | 40702 | 519 | 31656109 |
Proteinuria | 28.37 | 10.52 | 65 | 40651 | 16698 | 31639930 |
Speech disorder developmental | 26.96 | 10.52 | 22 | 40694 | 2069 | 31654559 |
Hepatic function abnormal | 26.42 | 10.52 | 114 | 40602 | 41108 | 31615520 |
Chronic kidney disease | 25.87 | 10.52 | 107 | 40609 | 37868 | 31618760 |
Gene mutation | 25.64 | 10.52 | 17 | 40699 | 1161 | 31655467 |
Aplasia pure red cell | 25.37 | 10.52 | 34 | 40682 | 5703 | 31650925 |
Foetal exposure timing unspecified | 25.27 | 10.52 | 10 | 40706 | 226 | 31656402 |
Hypotonic-hyporesponsive episode | 25.18 | 10.52 | 6 | 40710 | 20 | 31656608 |
Incision site pain | 25.14 | 10.52 | 20 | 40696 | 1814 | 31654814 |
Malignant hypertension | 23.70 | 10.52 | 13 | 40703 | 628 | 31656000 |
Blood pressure increased | 23.53 | 10.52 | 179 | 40537 | 79454 | 31577174 |
Death | 23.27 | 10.52 | 325 | 40391 | 360244 | 31296384 |
Cardiac arrest | 22.94 | 10.52 | 194 | 40522 | 88868 | 31567760 |
Haemodilution | 22.05 | 10.52 | 6 | 40710 | 38 | 31656590 |
Pyelocaliectasis | 21.72 | 10.52 | 15 | 40701 | 1096 | 31655532 |
Thrombotic cerebral infarction | 21.64 | 10.52 | 10 | 40706 | 334 | 31656294 |
Pre-eclampsia | 21.41 | 10.52 | 6 | 40710 | 43 | 31656585 |
Oedema | 20.92 | 10.52 | 109 | 40607 | 42452 | 31614176 |
Myocardial infarction | 20.31 | 10.52 | 229 | 40487 | 113225 | 31543403 |
Blood pressure decreased | 20.18 | 10.52 | 118 | 40598 | 47973 | 31608655 |
Anti-erythropoietin antibody positive | 20.10 | 10.52 | 13 | 40703 | 851 | 31655777 |
Lymphocyte count decreased | 19.80 | 10.52 | 65 | 40651 | 20584 | 31636044 |
Procedural hypertension | 19.64 | 10.52 | 6 | 40710 | 60 | 31656568 |
Renal failure | 19.47 | 10.52 | 243 | 40473 | 123087 | 31533541 |
Drug dependence | 19.21 | 10.52 | 3 | 40713 | 22576 | 31634052 |
Cutaneous lupus erythematosus | 19.17 | 10.52 | 12 | 40704 | 742 | 31655886 |
Hypotension | 19.16 | 10.52 | 369 | 40347 | 204249 | 31452379 |
HIV associated nephropathy | 19.06 | 10.52 | 9 | 40707 | 316 | 31656312 |
Intestinal pseudo-obstruction | 19.04 | 10.52 | 16 | 40700 | 1567 | 31655061 |
Atrioventricular block complete | 18.89 | 10.52 | 37 | 40679 | 8528 | 31648100 |
Congenital cystic lung | 18.69 | 10.52 | 8 | 40708 | 222 | 31656406 |
Treatment failure | 18.65 | 10.52 | 15 | 40701 | 40777 | 31615851 |
Attention deficit hyperactivity disorder | 18.65 | 10.52 | 19 | 40697 | 2379 | 31654249 |
Photosensitivity reaction | 18.55 | 10.52 | 40 | 40676 | 9864 | 31646764 |
Apnoeic attack | 18.37 | 10.52 | 9 | 40707 | 343 | 31656285 |
Blood pressure inadequately controlled | 18.19 | 10.52 | 19 | 40697 | 2450 | 31654178 |
Supernumerary nipple | 17.58 | 10.52 | 5 | 40711 | 38 | 31656590 |
Mixed connective tissue disease | 17.58 | 10.52 | 5 | 40711 | 38 | 31656590 |
Hypertensive crisis | 17.43 | 10.52 | 35 | 40681 | 8212 | 31648416 |
Patent ductus arteriosus | 17.40 | 10.52 | 21 | 40695 | 3172 | 31653456 |
Renal ischaemia | 17.36 | 10.52 | 10 | 40706 | 531 | 31656097 |
Blindness | 17.32 | 10.52 | 45 | 40671 | 12506 | 31644122 |
Renal disorder | 17.20 | 10.52 | 68 | 40648 | 23577 | 31633051 |
Lacunar infarction | 17.12 | 10.52 | 20 | 40696 | 2920 | 31653708 |
Rickets | 16.74 | 10.52 | 5 | 40711 | 46 | 31656582 |
Squamous cell carcinoma of skin | 16.72 | 10.52 | 39 | 40677 | 10135 | 31646493 |
Cell marker increased | 16.63 | 10.52 | 9 | 40707 | 423 | 31656205 |
Metabolic acidosis | 16.53 | 10.52 | 97 | 40619 | 39480 | 31617148 |
Myocardial ischaemia | 16.46 | 10.52 | 53 | 40663 | 16614 | 31640014 |
Eating disorder symptom | 16.42 | 10.52 | 4 | 40712 | 15 | 31656613 |
Caesarean section | 16.27 | 10.52 | 16 | 40700 | 1920 | 31654708 |
Hydrops foetalis | 16.07 | 10.52 | 9 | 40707 | 453 | 31656175 |
Acute kidney injury | 15.96 | 10.52 | 471 | 40245 | 279243 | 31377385 |
Congenital pulmonary valve atresia | 15.94 | 10.52 | 5 | 40711 | 55 | 31656573 |
Rheumatoid arthritis | 15.84 | 10.52 | 23 | 40693 | 47786 | 31608842 |
Systemic scleroderma | 15.84 | 10.52 | 8 | 40708 | 326 | 31656302 |
Pulmonary eosinophilia | 15.72 | 10.52 | 7 | 40709 | 214 | 31656414 |
Febrile neutropenia | 15.68 | 10.52 | 92 | 40624 | 121757 | 31534871 |
Wrong technique in product usage process | 15.57 | 10.52 | 12 | 40704 | 33331 | 31623297 |
Neonatal respiratory failure | 15.35 | 10.52 | 8 | 40708 | 348 | 31656280 |
Pituitary tumour recurrent | 15.32 | 10.52 | 5 | 40711 | 63 | 31656565 |
Abdominal symptom | 15.29 | 10.52 | 9 | 40707 | 498 | 31656130 |
Azotaemia | 15.19 | 10.52 | 24 | 40692 | 4668 | 31651960 |
Polyhydramnios | 15.06 | 10.52 | 7 | 40709 | 237 | 31656391 |
Cerebrovascular accident | 14.93 | 10.52 | 162 | 40554 | 79322 | 31577306 |
Sclerodactylia | 14.88 | 10.52 | 4 | 40712 | 24 | 31656604 |
Prinzmetal angina | 14.86 | 10.52 | 11 | 40705 | 896 | 31655732 |
Neonatal respiratory distress | 14.78 | 10.52 | 9 | 40707 | 530 | 31656098 |
Hyphaema | 14.76 | 10.52 | 9 | 40707 | 531 | 31656097 |
Post procedural urine leak | 14.71 | 10.52 | 6 | 40710 | 147 | 31656481 |
Drug interaction | 14.69 | 10.52 | 361 | 40355 | 208182 | 31448446 |
Brain stem infarction | 14.56 | 10.52 | 12 | 40704 | 1144 | 31655484 |
Meningitis staphylococcal | 14.53 | 10.52 | 5 | 40711 | 75 | 31656553 |
Naevus flammeus | 14.49 | 10.52 | 6 | 40710 | 153 | 31656475 |
Aortic dissection | 14.42 | 10.52 | 17 | 40699 | 2505 | 31654123 |
Interstitial lung disease | 14.37 | 10.52 | 131 | 40585 | 61272 | 31595356 |
Fatigue | 14.29 | 10.52 | 325 | 40391 | 334881 | 31321747 |
Bronchopulmonary dysplasia | 14.23 | 10.52 | 9 | 40707 | 567 | 31656061 |
Chorioretinopathy | 14.21 | 10.52 | 13 | 40703 | 1426 | 31655202 |
Nausea | 14.16 | 10.52 | 295 | 40421 | 307652 | 31348976 |
Cerebral hyperperfusion syndrome | 14.12 | 10.52 | 5 | 40711 | 82 | 31656546 |
Red blood cells urine positive | 14.05 | 10.52 | 14 | 40702 | 1708 | 31654920 |
Oesophageal haemorrhage | 13.97 | 10.52 | 12 | 40704 | 1211 | 31655417 |
Crepitations | 13.95 | 10.52 | 18 | 40698 | 2910 | 31653718 |
Nephrogenic systemic fibrosis | 13.89 | 10.52 | 21 | 40695 | 3934 | 31652694 |
Thrombocytopenia | 13.85 | 10.52 | 117 | 40599 | 142630 | 31513998 |
Palatal swelling | 13.67 | 10.52 | 4 | 40712 | 34 | 31656594 |
Agitation | 13.54 | 10.52 | 31 | 40685 | 54138 | 31602490 |
Oedema peripheral | 13.49 | 10.52 | 207 | 40509 | 109632 | 31546996 |
Ventricular extrasystoles | 13.43 | 10.52 | 38 | 40678 | 11104 | 31645524 |
Congenital hearing disorder | 13.34 | 10.52 | 5 | 40711 | 97 | 31656531 |
Tubulointerstitial nephritis | 13.29 | 10.52 | 53 | 40663 | 18443 | 31638185 |
BRASH syndrome | 13.22 | 10.52 | 7 | 40709 | 315 | 31656313 |
Hydrocele male infected | 13.10 | 10.52 | 4 | 40712 | 40 | 31656588 |
Exposure during pregnancy | 13.09 | 10.52 | 32 | 40684 | 8566 | 31648062 |
Acute lung injury | 12.97 | 10.52 | 12 | 40704 | 1335 | 31655293 |
Vomiting | 12.97 | 10.52 | 206 | 40510 | 223767 | 31432861 |
Neonatal respiratory distress syndrome | 12.76 | 10.52 | 20 | 40696 | 3865 | 31652763 |
Product use in unapproved indication | 12.69 | 10.52 | 75 | 40641 | 99096 | 31557532 |
Neonatal cholestasis | 12.67 | 10.52 | 4 | 40712 | 45 | 31656583 |
Maternal exposure during pregnancy | 12.64 | 10.52 | 22 | 40694 | 4634 | 31651994 |
Renal failure neonatal | 12.63 | 10.52 | 5 | 40711 | 113 | 31656515 |
Transplant rejection | 12.58 | 10.52 | 34 | 40682 | 9674 | 31646954 |
Bradycardia foetal | 12.50 | 10.52 | 7 | 40709 | 352 | 31656276 |
Chronic allograft nephropathy | 12.47 | 10.52 | 11 | 40705 | 1151 | 31655477 |
Infantile apnoea | 12.41 | 10.52 | 10 | 40706 | 924 | 31655704 |
Product residue present | 12.26 | 10.52 | 16 | 40700 | 2614 | 31654014 |
Diabetes mellitus | 12.19 | 10.52 | 95 | 40621 | 42461 | 31614167 |
Neuropathy peripheral | 12.07 | 10.52 | 53 | 40663 | 75596 | 31581032 |
Neutrophil count increased | 12.06 | 10.52 | 46 | 40670 | 15685 | 31640943 |
Pulmonary oedema | 12.01 | 10.52 | 98 | 40618 | 44404 | 31612224 |
Hypocalcaemia | 12.00 | 10.52 | 58 | 40658 | 21920 | 31634708 |
Kidney infection | 11.99 | 10.52 | 22 | 40694 | 4828 | 31651800 |
Blood pressure systolic | 11.97 | 10.52 | 3 | 40713 | 13 | 31656615 |
Cardiac cirrhosis | 11.88 | 10.52 | 4 | 40712 | 56 | 31656572 |
Putamen haemorrhage | 11.78 | 10.52 | 6 | 40710 | 249 | 31656379 |
Therapeutic product effect incomplete | 11.75 | 10.52 | 24 | 40692 | 43672 | 31612956 |
Peripheral arterial occlusive disease | 11.71 | 10.52 | 23 | 40693 | 5310 | 31651318 |
White blood cell count increased | 11.69 | 10.52 | 88 | 40628 | 38912 | 31617716 |
Hyperuricaemia | 11.66 | 10.52 | 28 | 40688 | 7410 | 31649218 |
Vertebral artery stenosis | 11.54 | 10.52 | 5 | 40711 | 143 | 31656485 |
Skin hypertrophy | 11.50 | 10.52 | 15 | 40701 | 2450 | 31654178 |
Haemoglobin decreased | 11.49 | 10.52 | 206 | 40510 | 112469 | 31544159 |
Psoriasis | 11.46 | 10.52 | 27 | 40689 | 46692 | 31609936 |
Joint range of motion decreased | 11.46 | 10.52 | 26 | 40690 | 6635 | 31649993 |
Angina unstable | 11.42 | 10.52 | 36 | 40680 | 11159 | 31645469 |
Anti-neutrophil cytoplasmic antibody positive vasculitis | 11.35 | 10.52 | 9 | 40707 | 812 | 31655816 |
Maternal drugs affecting foetus | 11.33 | 10.52 | 19 | 40697 | 3884 | 31652744 |
Retinopathy of prematurity | 11.29 | 10.52 | 5 | 40711 | 151 | 31656477 |
Serotonin syndrome | 11.25 | 10.52 | 5 | 40711 | 18768 | 31637860 |
Cardiac murmur | 11.20 | 10.52 | 26 | 40690 | 6736 | 31649892 |
Postrenal failure | 11.11 | 10.52 | 7 | 40709 | 438 | 31656190 |
Clonic convulsion | 11.07 | 10.52 | 8 | 40708 | 628 | 31656000 |
Hepatocellular injury | 11.06 | 10.52 | 7 | 40709 | 21537 | 31635091 |
Intentional product use issue | 10.96 | 10.52 | 30 | 40686 | 49317 | 31607311 |
Anaemia neonatal | 10.93 | 10.52 | 6 | 40710 | 290 | 31656338 |
Atrioventricular block | 10.90 | 10.52 | 27 | 40689 | 7288 | 31649340 |
Drug level increased | 10.83 | 10.52 | 53 | 40663 | 20133 | 31636495 |
Ventricular septal defect | 10.81 | 10.52 | 18 | 40698 | 3659 | 31652969 |
Cerebrovascular insufficiency | 10.77 | 10.52 | 3 | 40713 | 21 | 31656607 |
Pemphigoid | 10.75 | 10.52 | 29 | 40687 | 8242 | 31648386 |
Angina pectoris | 10.71 | 10.52 | 70 | 40646 | 29571 | 31627057 |
Suspected suicide | 10.62 | 10.52 | 19 | 40697 | 4088 | 31652540 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Premature delivery | 373.57 | 9.70 | 263 | 85703 | 21041 | 70821437 |
Exposure during pregnancy | 255.69 | 9.70 | 414 | 85552 | 87303 | 70755175 |
Hypertension | 157.52 | 9.70 | 743 | 85223 | 295290 | 70547188 |
Pre-eclampsia | 149.65 | 9.70 | 95 | 85871 | 6390 | 70836088 |
Renal impairment | 130.05 | 9.70 | 427 | 85539 | 143510 | 70698968 |
Cerebral infarction | 100.30 | 9.70 | 184 | 85782 | 42825 | 70799653 |
Drug abuse | 96.91 | 9.70 | 29 | 85937 | 147227 | 70695251 |
Bradycardia | 92.07 | 9.70 | 346 | 85620 | 124269 | 70718209 |
Dysplastic naevus | 88.04 | 9.70 | 31 | 85935 | 531 | 70841947 |
Cardiac failure congestive | 86.27 | 9.70 | 359 | 85607 | 135098 | 70707380 |
Photodermatosis | 85.91 | 9.70 | 35 | 85931 | 908 | 70841570 |
Hypotension | 83.65 | 9.70 | 802 | 85164 | 403579 | 70438899 |
Alopecia | 83.10 | 9.70 | 71 | 85895 | 198419 | 70644059 |
Premature labour | 82.08 | 9.70 | 72 | 85894 | 7928 | 70834550 |
Maternal exposure during pregnancy | 80.87 | 9.70 | 315 | 85651 | 115030 | 70727448 |
Blood pressure inadequately controlled | 75.47 | 9.70 | 59 | 85907 | 5533 | 70836945 |
Blood creatinine increased | 75.21 | 9.70 | 358 | 85608 | 142643 | 70699835 |
Neovascularisation | 72.97 | 9.70 | 33 | 85933 | 1112 | 70841366 |
Solar lentigo | 72.23 | 9.70 | 32 | 85934 | 1026 | 70841452 |
Hyperkalaemia | 71.42 | 9.70 | 287 | 85679 | 106304 | 70736174 |
Proteinuria | 70.17 | 9.70 | 127 | 85839 | 29247 | 70813231 |
Neutropenia | 68.19 | 9.70 | 130 | 85836 | 257026 | 70585452 |
Blood pressure increased | 67.47 | 9.70 | 425 | 85541 | 188092 | 70654386 |
Oedema peripheral | 67.18 | 9.70 | 490 | 85476 | 227601 | 70614877 |
Pemphigus | 65.34 | 9.70 | 11 | 85955 | 83025 | 70759453 |
Therapeutic product effect decreased | 65.09 | 9.70 | 47 | 85919 | 142971 | 70699507 |
Blood urea increased | 63.65 | 9.70 | 159 | 85807 | 45750 | 70796728 |
Gingival hypertrophy | 63.27 | 9.70 | 41 | 85925 | 2857 | 70839621 |
Pericarditis | 60.82 | 9.70 | 14 | 85952 | 84691 | 70757787 |
Glossodynia | 58.79 | 9.70 | 16 | 85950 | 86471 | 70756007 |
Aplastic anaemia | 57.18 | 9.70 | 85 | 85881 | 16631 | 70825847 |
Rheumatoid arthritis | 56.44 | 9.70 | 174 | 85792 | 291631 | 70550847 |
Shock | 53.94 | 9.70 | 138 | 85828 | 40287 | 70802191 |
Wound | 52.52 | 9.70 | 27 | 85939 | 98705 | 70743773 |
Caesarean section | 50.10 | 9.70 | 66 | 85900 | 11541 | 70830937 |
Duodenal ulcer perforation | 49.89 | 9.70 | 3 | 85963 | 51109 | 70791369 |
Hypersensitivity | 49.60 | 9.70 | 130 | 85836 | 229682 | 70612796 |
Pulmonary oedema | 49.21 | 9.70 | 214 | 85752 | 82064 | 70760414 |
Drug ineffective | 49.15 | 9.70 | 823 | 85143 | 938929 | 69903549 |
Completed suicide | 49.10 | 9.70 | 455 | 85511 | 226680 | 70615798 |
Primary hyperaldosteronism | 48.25 | 9.70 | 14 | 85952 | 123 | 70842355 |
Joint swelling | 47.53 | 9.70 | 153 | 85813 | 253058 | 70589420 |
Discomfort | 46.23 | 9.70 | 36 | 85930 | 105400 | 70737078 |
Arthropathy | 46.07 | 9.70 | 69 | 85897 | 149988 | 70692490 |
Kidney transplant rejection | 45.12 | 9.70 | 58 | 85908 | 9903 | 70832575 |
Infusion related reaction | 44.75 | 9.70 | 109 | 85857 | 197425 | 70645053 |
Hepatic function abnormal | 44.66 | 9.70 | 182 | 85784 | 67814 | 70774664 |
Contraindicated product administered | 44.20 | 9.70 | 59 | 85907 | 134553 | 70707925 |
Off label use | 44.12 | 9.70 | 635 | 85331 | 742425 | 70100053 |
Rheumatoid factor positive | 43.94 | 9.70 | 4 | 85962 | 48396 | 70794082 |
Blood pressure decreased | 43.03 | 9.70 | 222 | 85744 | 91293 | 70751185 |
Foetal growth restriction | 41.53 | 9.70 | 27 | 85939 | 1892 | 70840586 |
Angina unstable | 40.90 | 9.70 | 71 | 85895 | 15822 | 70826656 |
Myocardial infarction | 40.76 | 9.70 | 351 | 85615 | 171294 | 70671184 |
Hypertensive crisis | 40.67 | 9.70 | 79 | 85887 | 19183 | 70823295 |
Synovitis | 40.08 | 9.70 | 59 | 85907 | 129169 | 70713309 |
Bezoar | 39.32 | 9.70 | 28 | 85938 | 2278 | 70840200 |
Cerebrovascular accident | 39.25 | 9.70 | 303 | 85663 | 143167 | 70699311 |
Helicobacter infection | 38.39 | 9.70 | 10 | 85956 | 55646 | 70786832 |
Bladder prolapse | 38.10 | 9.70 | 22 | 85944 | 1245 | 70841233 |
Oedema | 37.32 | 9.70 | 234 | 85732 | 103347 | 70739131 |
Pulmonary hypertension | 36.67 | 9.70 | 132 | 85834 | 46404 | 70796074 |
Malignant hypertension | 36.62 | 9.70 | 23 | 85943 | 1518 | 70840960 |
Treatment failure | 36.34 | 9.70 | 75 | 85891 | 144067 | 70698411 |
Wrong technique in product usage process | 36.21 | 9.70 | 19 | 85947 | 68679 | 70773799 |
Scleroderma | 36 | 9.70 | 37 | 85929 | 4964 | 70837514 |
Drug interaction | 35.73 | 9.70 | 655 | 85311 | 380786 | 70461692 |
Psoriasis | 35.63 | 9.70 | 40 | 85926 | 98393 | 70744085 |
Renal failure | 35.58 | 9.70 | 368 | 85598 | 188702 | 70653776 |
Muscle injury | 35.43 | 9.70 | 3 | 85963 | 38491 | 70803987 |
Tubulointerstitial nephritis | 35.26 | 9.70 | 104 | 85862 | 32972 | 70809506 |
Chronic kidney disease | 35.13 | 9.70 | 157 | 85809 | 60900 | 70781578 |
Renal artery stenosis | 34.58 | 9.70 | 30 | 85936 | 3254 | 70839224 |
Intestinal angioedema | 34.48 | 9.70 | 18 | 85948 | 834 | 70841644 |
Cardiac arrest | 34.42 | 9.70 | 320 | 85646 | 159514 | 70682964 |
Actinic keratosis | 34.31 | 9.70 | 38 | 85928 | 5552 | 70836926 |
Blood aldosterone increased | 33.84 | 9.70 | 12 | 85954 | 210 | 70842268 |
Phaeochromocytoma | 33.56 | 9.70 | 16 | 85950 | 609 | 70841869 |
Rectal prolapse | 33.14 | 9.70 | 24 | 85942 | 2005 | 70840473 |
Dialysis | 32.71 | 9.70 | 68 | 85898 | 17334 | 70825144 |
Anuria | 32.59 | 9.70 | 73 | 85893 | 19580 | 70822898 |
Aortic dissection | 32.39 | 9.70 | 31 | 85935 | 3816 | 70838662 |
Blood pressure systolic abnormal | 32.35 | 9.70 | 57 | 85909 | 12852 | 70829626 |
Hepatic enzyme increased | 32.21 | 9.70 | 91 | 85875 | 156899 | 70685579 |
Blood pressure diastolic abnormal | 32.02 | 9.70 | 63 | 85903 | 15441 | 70827037 |
Drug intolerance | 31.73 | 9.70 | 153 | 85813 | 225534 | 70616944 |
Eclampsia | 31.48 | 9.70 | 11 | 85955 | 184 | 70842294 |
Lower respiratory tract infection | 31.03 | 9.70 | 55 | 85911 | 111858 | 70730620 |
Cardiac failure | 30.71 | 9.70 | 287 | 85679 | 143254 | 70699224 |
Impaired healing | 30.62 | 9.70 | 27 | 85939 | 74347 | 70768131 |
BRASH syndrome | 30.28 | 9.70 | 15 | 85951 | 622 | 70841856 |
Febrile neutropenia | 30.20 | 9.70 | 136 | 85830 | 204182 | 70638296 |
Intestinal pseudo-obstruction | 30.18 | 9.70 | 24 | 85942 | 2306 | 70840172 |
Fatigue | 30.18 | 9.70 | 765 | 85201 | 823554 | 70018924 |
Metabolic acidosis | 29.99 | 9.70 | 173 | 85793 | 74173 | 70768305 |
Sinusitis | 29.84 | 9.70 | 105 | 85861 | 169090 | 70673388 |
Angina pectoris | 29.81 | 9.70 | 127 | 85839 | 48256 | 70794222 |
Polyhydramnios | 29.71 | 9.70 | 20 | 85946 | 1486 | 70840992 |
Hyperuricaemia | 29.55 | 9.70 | 50 | 85916 | 10916 | 70831562 |
Protein urine present | 29.45 | 9.70 | 46 | 85920 | 9394 | 70833084 |
Injection site erythema | 29.39 | 9.70 | 27 | 85939 | 72897 | 70769581 |
Hypergammaglobulinaemia | 29.31 | 9.70 | 15 | 85951 | 667 | 70841811 |
Adverse drug reaction | 29.25 | 9.70 | 14 | 85952 | 53330 | 70789148 |
Systemic lupus erythematosus | 29.24 | 9.70 | 49 | 85917 | 101853 | 70740625 |
Incision site pain | 28.62 | 9.70 | 25 | 85941 | 2736 | 70839742 |
Superimposed pre-eclampsia | 28.58 | 9.70 | 5 | 85961 | 0 | 70842478 |
Acute pulmonary oedema | 28.30 | 9.70 | 55 | 85911 | 13357 | 70829121 |
Uraemic encephalopathy | 28.27 | 9.70 | 14 | 85952 | 580 | 70841898 |
Heart rate decreased | 28.15 | 9.70 | 149 | 85817 | 61866 | 70780612 |
Atrioventricular block first degree | 27.28 | 9.70 | 50 | 85916 | 11623 | 70830855 |
Oligohydramnios | 27.08 | 9.70 | 26 | 85940 | 3214 | 70839264 |
Haemoglobin decreased | 27.00 | 9.70 | 373 | 85593 | 204786 | 70637692 |
Systemic scleroderma | 26.98 | 9.70 | 17 | 85949 | 1128 | 70841350 |
Product use issue | 26.45 | 9.70 | 120 | 85846 | 179817 | 70662661 |
CD30 expression | 26.31 | 9.70 | 7 | 85959 | 43 | 70842435 |
Dyspnoea exertional | 26.29 | 9.70 | 174 | 85792 | 78256 | 70764222 |
Wrist deformity | 25.90 | 9.70 | 20 | 85946 | 1842 | 70840636 |
Drug dispensed to wrong patient | 25.67 | 9.70 | 13 | 85953 | 565 | 70841913 |
Rash | 25.63 | 9.70 | 450 | 85516 | 510112 | 70332366 |
Lacunar infarction | 25.54 | 9.70 | 33 | 85933 | 5663 | 70836815 |
Oesophageal obstruction | 25.38 | 9.70 | 15 | 85951 | 887 | 70841591 |
Psoriatic arthropathy | 24.91 | 9.70 | 25 | 85941 | 64746 | 70777732 |
Atrioventricular block complete | 24.78 | 9.70 | 56 | 85910 | 15107 | 70827371 |
Acute myocardial infarction | 24.61 | 9.70 | 162 | 85804 | 72725 | 70769753 |
Renin decreased | 24.14 | 9.70 | 8 | 85958 | 113 | 70842365 |
Coronary artery disease | 24.02 | 9.70 | 144 | 85822 | 62592 | 70779886 |
Knee arthroplasty | 23.97 | 9.70 | 6 | 85960 | 34295 | 70808183 |
Transfusion | 23.79 | 9.70 | 63 | 85903 | 18773 | 70823705 |
White blood cell count increased | 23.71 | 9.70 | 155 | 85811 | 69418 | 70773060 |
Intentional product use issue | 23.65 | 9.70 | 71 | 85895 | 120071 | 70722407 |
Blood pressure systolic increased | 23.59 | 9.70 | 134 | 85832 | 57125 | 70785353 |
Phospholipidosis | 23.46 | 9.70 | 8 | 85958 | 124 | 70842354 |
Drug dependence | 23.38 | 9.70 | 8 | 85958 | 37313 | 70805165 |
Foetal death | 23.19 | 9.70 | 33 | 85933 | 6206 | 70836272 |
Intentional self-injury | 23.18 | 9.70 | 5 | 85961 | 31645 | 70810833 |
Pain | 23.12 | 9.70 | 583 | 85383 | 628233 | 70214245 |
Aplasia pure red cell | 23.10 | 9.70 | 36 | 85930 | 7338 | 70835140 |
Renal hypoplasia | 22.78 | 9.70 | 5 | 85961 | 11 | 70842467 |
Thrombocytopenia | 22.74 | 9.70 | 183 | 85783 | 238927 | 70603551 |
Peripartum cardiomyopathy | 22.56 | 9.70 | 8 | 85958 | 140 | 70842338 |
Low birth weight baby | 22.50 | 9.70 | 12 | 85954 | 581 | 70841897 |
Peripheral vascular disorder | 22.17 | 9.70 | 36 | 85930 | 7596 | 70834882 |
Infection | 22.09 | 9.70 | 157 | 85809 | 210628 | 70631850 |
Endometritis | 21.94 | 9.70 | 13 | 85953 | 772 | 70841706 |
Azotaemia | 21.76 | 9.70 | 36 | 85930 | 7717 | 70834761 |
Paradoxical drug reaction | 21.63 | 9.70 | 33 | 85933 | 6603 | 70835875 |
Altered state of consciousness | 21.60 | 9.70 | 101 | 85865 | 39921 | 70802557 |
Finger amputation | 21.57 | 9.70 | 12 | 85954 | 632 | 70841846 |
Hypervolaemia | 21.28 | 9.70 | 100 | 85866 | 39606 | 70802872 |
Dyspnoea | 21.21 | 9.70 | 1138 | 84828 | 768922 | 70073556 |
Myocardial ischaemia | 21.11 | 9.70 | 71 | 85895 | 24129 | 70818349 |
Umbilical cord vascular disorder | 20.98 | 9.70 | 5 | 85961 | 18 | 70842460 |
Diabetic nephropathy | 20.84 | 9.70 | 21 | 85945 | 2752 | 70839726 |
Premature baby | 20.46 | 9.70 | 23 | 85943 | 3416 | 70839062 |
Sedation | 20.42 | 9.70 | 16 | 85950 | 46715 | 70795763 |
Irritable bowel syndrome | 20.28 | 9.70 | 19 | 85947 | 50831 | 70791647 |
Fibromyalgia | 20.16 | 9.70 | 17 | 85949 | 47857 | 70794621 |
Acute kidney injury | 20.03 | 9.70 | 733 | 85233 | 473891 | 70368587 |
Prinzmetal angina | 19.60 | 9.70 | 16 | 85950 | 1596 | 70840882 |
HIV associated nephropathy | 19.48 | 9.70 | 9 | 85957 | 319 | 70842159 |
Therapeutic product effect incomplete | 19.43 | 9.70 | 77 | 85889 | 119805 | 70722673 |
Left ventricular hypertrophy | 19.33 | 9.70 | 40 | 85926 | 10162 | 70832316 |
Oesophageal haemorrhage | 19.23 | 9.70 | 16 | 85950 | 1639 | 70840839 |
Sclerodactylia | 19.11 | 9.70 | 7 | 85959 | 135 | 70842343 |
Electrocardiogram PR prolongation | 19.07 | 9.70 | 15 | 85951 | 1419 | 70841059 |
Preterm premature rupture of membranes | 19.04 | 9.70 | 14 | 85952 | 1197 | 70841281 |
Injection site pain | 18.78 | 9.70 | 76 | 85890 | 117543 | 70724935 |
Injection site inflammation | 18.77 | 9.70 | 22 | 85944 | 3416 | 70839062 |
Product complaint | 18.70 | 9.70 | 44 | 85922 | 12187 | 70830291 |
Respiratory tract inflammation | 18.69 | 9.70 | 12 | 85954 | 823 | 70841655 |
Stillbirth | 18.57 | 9.70 | 23 | 85943 | 3782 | 70838696 |
Thrombotic cerebral infarction | 18.49 | 9.70 | 10 | 85956 | 498 | 70841980 |
Renal disorder | 18.41 | 9.70 | 93 | 85873 | 37916 | 70804562 |
Abdominal discomfort | 18.31 | 9.70 | 169 | 85797 | 214489 | 70627989 |
Vascular resistance systemic increased | 18.16 | 9.70 | 4 | 85962 | 9 | 70842469 |
Photosensitivity reaction | 17.99 | 9.70 | 58 | 85908 | 19282 | 70823196 |
Sleep disorder | 17.90 | 9.70 | 36 | 85930 | 69836 | 70772642 |
Weight increased | 17.69 | 9.70 | 198 | 85768 | 242133 | 70600345 |
Pain in jaw | 17.67 | 9.70 | 100 | 85866 | 42569 | 70799909 |
Atrioventricular block | 17.64 | 9.70 | 44 | 85922 | 12644 | 70829834 |
Product residue present | 17.47 | 9.70 | 21 | 85945 | 3349 | 70839129 |
Intracardiac mass | 17.36 | 9.70 | 6 | 85960 | 97 | 70842381 |
Arthralgia | 17.34 | 9.70 | 471 | 85495 | 502919 | 70339559 |
Hypertensive emergency | 17.33 | 9.70 | 18 | 85948 | 2445 | 70840033 |
Ventricular extrasystoles | 17.27 | 9.70 | 55 | 85911 | 18171 | 70824307 |
Neuropathy peripheral | 17.26 | 9.70 | 87 | 85879 | 126809 | 70715669 |
Multiple sclerosis relapse | 17.24 | 9.70 | 16 | 85950 | 43001 | 70799477 |
Condition aggravated | 17.19 | 9.70 | 391 | 85575 | 427244 | 70415234 |
Tocolysis | 17.15 | 9.70 | 3 | 85963 | 0 | 70842478 |
Haemodialysis | 17.00 | 9.70 | 53 | 85913 | 17313 | 70825165 |
Barotrauma | 16.85 | 9.70 | 7 | 85959 | 191 | 70842287 |
Pemphigoid | 16.80 | 9.70 | 46 | 85920 | 13976 | 70828502 |
Small for dates baby | 16.80 | 9.70 | 9 | 85957 | 440 | 70842038 |
General physical health deterioration | 16.78 | 9.70 | 194 | 85772 | 235837 | 70606641 |
Thermal burn | 16.72 | 9.70 | 29 | 85937 | 6457 | 70836021 |
Squamous cell carcinoma of skin | 16.55 | 9.70 | 43 | 85923 | 12669 | 70829809 |
Skin hypertrophy | 16.40 | 9.70 | 24 | 85942 | 4628 | 70837850 |
Hepatocellular injury | 16.38 | 9.70 | 19 | 85947 | 46072 | 70796406 |
Neutrophil count increased | 16.24 | 9.70 | 70 | 85896 | 26725 | 70815753 |
Injection site reaction | 16.20 | 9.70 | 22 | 85944 | 49830 | 70792648 |
Putamen haemorrhage | 16.11 | 9.70 | 9 | 85957 | 478 | 70842000 |
Nodular regenerative hyperplasia | 16.07 | 9.70 | 13 | 85953 | 1280 | 70841198 |
Hip arthroplasty | 15.93 | 9.70 | 7 | 85959 | 28033 | 70814445 |
Platelet transfusion | 15.85 | 9.70 | 16 | 85950 | 2102 | 70840376 |
Product use in unapproved indication | 15.75 | 9.70 | 168 | 85798 | 207310 | 70635168 |
Brain stem infarction | 15.72 | 9.70 | 15 | 85951 | 1840 | 70840638 |
Palpitations | 15.64 | 9.70 | 204 | 85762 | 110549 | 70731929 |
Nephrogenic systemic fibrosis | 15.52 | 9.70 | 27 | 85939 | 6025 | 70836453 |
Maternal condition affecting foetus | 15.40 | 9.70 | 6 | 85960 | 138 | 70842340 |
Hypertensive encephalopathy | 15.38 | 9.70 | 11 | 85955 | 901 | 70841577 |
HELLP syndrome | 15.34 | 9.70 | 10 | 85956 | 704 | 70841774 |
Hypocalcaemia | 15.32 | 9.70 | 100 | 85866 | 44759 | 70797719 |
Haemodilution | 15.20 | 9.70 | 6 | 85960 | 143 | 70842335 |
Aggression | 15.13 | 9.70 | 22 | 85944 | 48424 | 70794054 |
Cognitive disorder | 15.12 | 9.70 | 32 | 85934 | 60924 | 70781554 |
Diabetes mellitus | 15.05 | 9.70 | 143 | 85823 | 71681 | 70770797 |
Premature separation of placenta | 15.03 | 9.70 | 12 | 85954 | 1160 | 70841318 |
Blood lactate dehydrogenase increased | 14.99 | 9.70 | 83 | 85883 | 35044 | 70807434 |
Wheezing | 14.93 | 9.70 | 61 | 85905 | 94109 | 70748369 |
Nephrotic syndrome | 14.90 | 9.70 | 37 | 85929 | 10603 | 70831875 |
Gastroenteritis | 14.86 | 9.70 | 76 | 85890 | 31137 | 70811341 |
Peritoneal dialysis complication | 14.77 | 9.70 | 16 | 85950 | 2280 | 70840198 |
Vitamin D decreased | 14.76 | 9.70 | 32 | 85934 | 8395 | 70834083 |
Nephrogenic anaemia | 14.74 | 9.70 | 20 | 85946 | 3598 | 70838880 |
Nodal rhythm | 14.71 | 9.70 | 18 | 85948 | 2923 | 70839555 |
Urticaria | 14.49 | 9.70 | 127 | 85839 | 162922 | 70679556 |
Tricuspid valve incompetence | 14.43 | 9.70 | 51 | 85915 | 17766 | 70824712 |
Accidental exposure to product | 14.43 | 9.70 | 8 | 85958 | 28043 | 70814435 |
Lymphocyte count decreased | 14.23 | 9.70 | 96 | 85870 | 43443 | 70799035 |
Mucosal erosion | 14.22 | 9.70 | 15 | 85951 | 2074 | 70840404 |
Gestational hypertension | 14.21 | 9.70 | 14 | 85952 | 1786 | 70840692 |
Swelling | 14.17 | 9.70 | 153 | 85813 | 188386 | 70654092 |
Amniotic cavity infection | 14.16 | 9.70 | 10 | 85956 | 803 | 70841675 |
Porphyria acute | 14.11 | 9.70 | 12 | 85954 | 1267 | 70841211 |
Procedural hypertension | 14.09 | 9.70 | 7 | 85959 | 292 | 70842186 |
Peritoneal dialysis | 14.05 | 9.70 | 10 | 85956 | 813 | 70841665 |
Hyphaema | 14.05 | 9.70 | 10 | 85956 | 813 | 70841665 |
Peripheral ischaemia | 13.93 | 9.70 | 32 | 85934 | 8726 | 70833752 |
Ventricular hypertrophy | 13.89 | 9.70 | 27 | 85939 | 6557 | 70835921 |
Blood pressure diastolic decreased | 13.87 | 9.70 | 65 | 85901 | 25715 | 70816763 |
Foot deformity | 13.70 | 9.70 | 4 | 85962 | 20651 | 70821827 |
Fluid retention | 13.68 | 9.70 | 127 | 85839 | 63258 | 70779220 |
Human chorionic gonadotropin positive | 13.60 | 9.70 | 4 | 85962 | 37 | 70842441 |
Blood albumin decreased | 13.56 | 9.70 | 58 | 85908 | 22069 | 70820409 |
Renal ischaemia | 13.52 | 9.70 | 11 | 85955 | 1092 | 70841386 |
Hyperplasia adrenal | 13.41 | 9.70 | 4 | 85962 | 39 | 70842439 |
Diabetic retinopathy | 13.33 | 9.70 | 17 | 85949 | 2880 | 70839598 |
Platelet count decreased | 13.30 | 9.70 | 296 | 85670 | 177926 | 70664552 |
Cardiac failure acute | 13.27 | 9.70 | 49 | 85917 | 17438 | 70825040 |
Hypoaesthesia teeth | 13.24 | 9.70 | 4 | 85962 | 41 | 70842437 |
Hot flush | 13.18 | 9.70 | 25 | 85941 | 49559 | 70792919 |
Brain natriuretic peptide increased | 13.16 | 9.70 | 30 | 85936 | 8141 | 70834337 |
Anti-erythropoietin antibody positive | 13.12 | 9.70 | 9 | 85957 | 690 | 70841788 |
Sinus arrhythmia | 13.10 | 9.70 | 14 | 85952 | 1964 | 70840514 |
Arteriospasm coronary | 13.07 | 9.70 | 25 | 85941 | 5999 | 70836479 |
Injection site pruritus | 13.05 | 9.70 | 17 | 85949 | 39193 | 70803285 |
Bradycardia foetal | 13.04 | 9.70 | 5 | 85961 | 110 | 70842368 |
Blood glucose increased | 13.04 | 9.70 | 186 | 85780 | 102796 | 70739682 |
Myocardial depression | 13.02 | 9.70 | 8 | 85958 | 508 | 70841970 |
COVID-19 | 13 | 9.70 | 75 | 85891 | 105682 | 70736796 |
Haemoperitoneum | 12.93 | 9.70 | 20 | 85946 | 4051 | 70838427 |
Peritonitis bacterial | 12.93 | 9.70 | 32 | 85934 | 9152 | 70833326 |
Cerebral hyperperfusion syndrome | 12.91 | 9.70 | 5 | 85961 | 113 | 70842365 |
Product substitution error | 12.90 | 9.70 | 4 | 85962 | 45 | 70842433 |
Renal atrophy | 12.90 | 9.70 | 13 | 85953 | 1704 | 70840774 |
Neutropenic sepsis | 12.89 | 9.70 | 7 | 85959 | 24823 | 70817655 |
Joint range of motion decreased | 12.83 | 9.70 | 64 | 85902 | 25962 | 70816516 |
Nasopharyngitis | 12.72 | 9.70 | 191 | 85775 | 222015 | 70620463 |
Muscle spasticity | 12.72 | 9.70 | 4 | 85962 | 19685 | 70822793 |
Meningitis staphylococcal | 12.67 | 9.70 | 5 | 85961 | 119 | 70842359 |
Paranasal sinus inflammation | 12.57 | 9.70 | 6 | 85960 | 229 | 70842249 |
Peripheral arterial occlusive disease | 12.57 | 9.70 | 28 | 85938 | 7481 | 70834997 |
Urine output decreased | 12.41 | 9.70 | 47 | 85919 | 16923 | 70825555 |
Diverticulum intestinal haemorrhagic | 12.39 | 9.70 | 18 | 85948 | 3449 | 70839029 |
Post transplant distal limb syndrome | 12.32 | 9.70 | 8 | 85958 | 559 | 70841919 |
Accidental exposure to product by child | 12.18 | 9.70 | 16 | 85950 | 2790 | 70839688 |
Red blood cells urine positive | 12.07 | 9.70 | 21 | 85945 | 4688 | 70837790 |
Interstitial lung disease | 12.05 | 9.70 | 186 | 85780 | 104499 | 70737979 |
Shunt stenosis | 11.87 | 9.70 | 11 | 85955 | 1301 | 70841177 |
Cardiomegaly | 11.85 | 9.70 | 60 | 85906 | 24485 | 70817993 |
Laboratory test interference | 11.84 | 9.70 | 10 | 85956 | 1046 | 70841432 |
Hydronephrosis | 11.81 | 9.70 | 43 | 85923 | 15199 | 70827279 |
Ileus paralytic | 11.78 | 9.70 | 30 | 85936 | 8731 | 70833747 |
Chorioretinopathy | 11.76 | 9.70 | 14 | 85952 | 2211 | 70840267 |
Apnoeic attack | 11.74 | 9.70 | 8 | 85958 | 606 | 70841872 |
Hepatic rupture | 11.73 | 9.70 | 4 | 85962 | 62 | 70842416 |
Blood pressure fluctuation | 11.63 | 9.70 | 116 | 85850 | 58896 | 70783582 |
Post procedural urine leak | 11.63 | 9.70 | 5 | 85961 | 149 | 70842329 |
Sinus bradycardia | 11.58 | 9.70 | 58 | 85908 | 23565 | 70818913 |
Pituitary tumour recurrent | 11.56 | 9.70 | 5 | 85961 | 151 | 70842327 |
Lactic acidosis | 11.48 | 9.70 | 125 | 85841 | 64899 | 70777579 |
Renal cyst haemorrhage | 11.40 | 9.70 | 8 | 85958 | 636 | 70841842 |
High density lipoprotein decreased | 11.39 | 9.70 | 19 | 85947 | 4100 | 70838378 |
Gastric cancer | 11.36 | 9.70 | 30 | 85936 | 8925 | 70833553 |
Heliotrope rash | 11.30 | 9.70 | 5 | 85961 | 160 | 70842318 |
Arteriosclerosis | 11.29 | 9.70 | 45 | 85921 | 16593 | 70825885 |
Fibroadenoma of breast | 11.26 | 9.70 | 6 | 85960 | 290 | 70842188 |
Decreased appetite | 11.25 | 9.70 | 464 | 85502 | 304316 | 70538162 |
Low density lipoprotein increased | 11.24 | 9.70 | 28 | 85938 | 8037 | 70834441 |
Frostbite | 11.21 | 9.70 | 5 | 85961 | 163 | 70842315 |
Shunt occlusion | 11.16 | 9.70 | 11 | 85955 | 1404 | 70841074 |
Mobility decreased | 11.13 | 9.70 | 76 | 85890 | 102923 | 70739555 |
Electrocardiogram QRS complex shortened | 11.08 | 9.70 | 8 | 85958 | 665 | 70841813 |
Dermatophytosis of nail | 11.04 | 9.70 | 5 | 85961 | 169 | 70842309 |
Ill-defined disorder | 11.02 | 9.70 | 32 | 85934 | 54709 | 70787769 |
Blood uric acid increased | 10.99 | 9.70 | 30 | 85936 | 9099 | 70833379 |
End stage renal disease | 10.92 | 9.70 | 34 | 85932 | 11099 | 70831379 |
Abdominal symptom | 10.89 | 9.70 | 8 | 85958 | 683 | 70841795 |
Arrhythmia | 10.89 | 9.70 | 110 | 85856 | 56033 | 70786445 |
Lip haemorrhage | 10.89 | 9.70 | 10 | 85956 | 1169 | 70841309 |
Clostridium difficile infection | 10.82 | 9.70 | 19 | 85947 | 38797 | 70803681 |
Hypermagnesaemia | 10.80 | 9.70 | 10 | 85956 | 1181 | 70841297 |
Pulmonary embolism | 10.72 | 9.70 | 129 | 85837 | 155738 | 70686740 |
Atrioventricular dissociation | 10.72 | 9.70 | 6 | 85960 | 320 | 70842158 |
Chest discomfort | 10.72 | 9.70 | 211 | 85755 | 124170 | 70718308 |
Periodontitis | 10.70 | 9.70 | 19 | 85947 | 4309 | 70838169 |
Renal-limited thrombotic microangiopathy | 10.70 | 9.70 | 3 | 85963 | 23 | 70842455 |
Cardiac failure chronic | 10.67 | 9.70 | 32 | 85934 | 10237 | 70832241 |
Bradyarrhythmia | 10.62 | 9.70 | 18 | 85948 | 3935 | 70838543 |
Pyuria | 10.60 | 9.70 | 13 | 85953 | 2117 | 70840361 |
Immunodeficiency | 10.59 | 9.70 | 4 | 85962 | 17551 | 70824927 |
Cervical incompetence | 10.56 | 9.70 | 7 | 85959 | 507 | 70841971 |
Vertebral artery stenosis | 10.55 | 9.70 | 5 | 85961 | 188 | 70842290 |
Device expulsion | 10.53 | 9.70 | 7 | 85959 | 22239 | 70820239 |
Foetal hypokinesia | 10.52 | 9.70 | 6 | 85960 | 332 | 70842146 |
Pancreatitis haemorrhagic | 10.50 | 9.70 | 8 | 85958 | 722 | 70841756 |
Transferrin decreased | 10.50 | 9.70 | 6 | 85960 | 333 | 70842145 |
Peripheral coldness | 10.48 | 9.70 | 40 | 85926 | 14460 | 70828018 |
Pulmonary arterial hypertension | 10.47 | 9.70 | 72 | 85894 | 32783 | 70809695 |
Cholestasis | 10.37 | 9.70 | 27 | 85939 | 47845 | 70794633 |
Peripheral embolism | 10.35 | 9.70 | 12 | 85954 | 1842 | 70840636 |
Pleural effusion | 10.33 | 9.70 | 222 | 85744 | 132642 | 70709836 |
Carotid artery disease | 10.30 | 9.70 | 13 | 85953 | 2180 | 70840298 |
Blood calcium increased | 10.28 | 9.70 | 29 | 85937 | 8964 | 70833514 |
Acantholysis | 10.28 | 9.70 | 3 | 85963 | 27 | 70842451 |
Gastric ileus | 10.28 | 9.70 | 3 | 85963 | 27 | 70842451 |
Restrictive cardiomyopathy | 10.27 | 9.70 | 9 | 85957 | 989 | 70841489 |
Cerebral haemorrhage | 10.19 | 9.70 | 105 | 85861 | 53759 | 70788719 |
Staphylococcal infection | 10.19 | 9.70 | 32 | 85934 | 53372 | 70789106 |
Vomiting | 10.14 | 9.70 | 602 | 85364 | 592509 | 70249969 |
Poisoning deliberate | 10.11 | 9.70 | 4 | 85962 | 17056 | 70825422 |
Raynaud's phenomenon | 10.05 | 9.70 | 9 | 85957 | 1018 | 70841460 |
Lymphopenia | 10.03 | 9.70 | 11 | 85955 | 27348 | 70815130 |
Ileal ulcer | 10.02 | 9.70 | 9 | 85957 | 1022 | 70841456 |
Mallory-Weiss syndrome | 9.98 | 9.70 | 14 | 85952 | 2597 | 70839881 |
Withdrawal hypertension | 9.97 | 9.70 | 6 | 85960 | 367 | 70842111 |
Atrioventricular block second degree | 9.95 | 9.70 | 24 | 85942 | 6754 | 70835724 |
Live birth | 9.95 | 9.70 | 38 | 85928 | 13741 | 70828737 |
Dehydration | 9.94 | 9.70 | 351 | 85615 | 225791 | 70616687 |
Urticaria pigmentosa | 9.90 | 9.70 | 3 | 85963 | 31 | 70842447 |
Crepitations | 9.86 | 9.70 | 28 | 85938 | 8686 | 70833792 |
Pseudolymphoma | 9.83 | 9.70 | 9 | 85957 | 1048 | 70841430 |
Colon gangrene | 9.82 | 9.70 | 3 | 85963 | 32 | 70842446 |
Vascular resistance systemic decreased | 9.82 | 9.70 | 5 | 85961 | 220 | 70842258 |
Complications of transplanted kidney | 9.79 | 9.70 | 22 | 85944 | 5912 | 70836566 |
Ear infection | 9.73 | 9.70 | 12 | 85954 | 28324 | 70814154 |
Glomerulonephritis membranoproliferative | 9.73 | 9.70 | 7 | 85959 | 579 | 70841899 |
Acute myeloid leukaemia | 9.71 | 9.70 | 14 | 85952 | 30926 | 70811552 |
Ischaemic skin ulcer | 9.70 | 9.70 | 4 | 85962 | 107 | 70842371 |
Gangrene | 9.70 | 9.70 | 27 | 85939 | 8282 | 70834196 |
None
Source | Code | Description |
---|---|---|
ATC | C07FB03 | CARDIOVASCULAR SYSTEM BETA BLOCKING AGENTS BETA BLOCKING AGENTS, OTHER COMBINATIONS Beta blocking agents and calcium channel blockers |
ATC | C08CA05 | CARDIOVASCULAR SYSTEM CALCIUM CHANNEL BLOCKERS SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS Dihydropyridine derivatives |
ATC | C08CA55 | CARDIOVASCULAR SYSTEM CALCIUM CHANNEL BLOCKERS SELECTIVE CALCIUM CHANNEL BLOCKERS WITH MAINLY VASCULAR EFFECTS Dihydropyridine derivatives |
ATC | C08GA01 | CARDIOVASCULAR SYSTEM CALCIUM CHANNEL BLOCKERS CALCIUM CHANNEL BLOCKERS AND DIURETICS Calcium channel blockers and diuretics |
FDA CS | M0006414 | Dihydropyridines |
FDA MoA | N0000000069 | Calcium Channel Antagonists |
FDA EPC | N0000175421 | Dihydropyridine Calcium Channel Blocker |
MeSH PA | D002121 | Calcium Channel Blockers |
MeSH PA | D000077264 | Calcium-Regulating Hormones and Agents |
MeSH PA | D002317 | Cardiovascular Agents |
MeSH PA | D049990 | Membrane Transport Modulators |
MeSH PA | D012102 | Reproductive Control Agents |
MeSH PA | D015149 | Tocolytic Agents |
MeSH PA | D014665 | Vasodilator Agents |
CHEBI has role | CHEBI:35620 | vasodilator agents |
CHEBI has role | CHEBI:38215 | calcium channel blockers |
CHEBI has role | CHEBI:66993 | tocolytic drugs |
CHEBI has role | CHEBI:77746 | Homo sapiens metabolite |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Hypertensive disorder | indication | 38341003 | DOID:10763 |
Prinzmetal angina | indication | 87343002 | |
Angina pectoris | indication | 194828000 | |
Premature labor | off-label use | 6383007 | |
Raynaud's phenomenon | off-label use | 266261006 | |
Cirrhosis of liver | contraindication | 19943007 | DOID:5082 |
Myocardial infarction | contraindication | 22298006 | DOID:5844 |
Stenosis of intestine | contraindication | 23065003 | |
Low blood pressure | contraindication | 45007003 | |
Chronic heart failure | contraindication | 48447003 | |
Chronic idiopathic constipation | contraindication | 82934008 | |
Left heart failure | contraindication | 85232009 | |
Cardiogenic shock | contraindication | 89138009 | |
Kidney disease | contraindication | 90708001 | DOID:557 |
Gastrointestinal obstruction | contraindication | 126765001 | |
Disease of liver | contraindication | 235856003 | DOID:409 |
Pyloric obstruction | contraindication | 244815007 | |
Peripheral edema | contraindication | 271809000 | |
Continent ileostomy - stoma | contraindication | 311414006 | |
Non-Q wave myocardial infarction | contraindication | 314207007 | |
Acute coronary syndrome | contraindication | 394659003 | |
Porphyria | contraindication | 418470004 | |
Severe Aortic Valve Stenosis | contraindication |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 2.5 | Basic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Voltage-dependent L-type calcium channel subunit alpha-1D | Ion channel | GATING INHIBITOR | IC50 | 7.70 | IUPHAR | CHEMBL | |||
Voltage-dependent L-type calcium channel subunit alpha-1C | Ion channel | BLOCKER | Kd | 9.40 | CHEMBL | SCIENTIFIC LITERATURE | |||
Adenosine receptor A2a | GPCR | Ki | 4.65 | CHEMBL | |||||
Potassium voltage-gated channel subfamily H member 2 | Ion channel | IC50 | 4.30 | WOMBAT-PK | |||||
Cytochrome P450 3A4 | Enzyme | IC50 | 5.26 | WOMBAT-PK | |||||
5-hydroxytryptamine receptor 2A | GPCR | Ki | 6.50 | PDSP | |||||
5-hydroxytryptamine receptor 2C | GPCR | Ki | 5.02 | DRUG MATRIX | |||||
Adenosine receptor A1 | GPCR | Ki | 5.35 | DRUG MATRIX | |||||
Adenosine receptor A3 | GPCR | Ki | 5.08 | CHEMBL | |||||
Glutathione reductase, mitochondrial | Enzyme | Ki | 4.76 | CHEMBL | |||||
Transthyretin | Secreted | IC50 | 5.66 | WOMBAT-PK | |||||
Glycine receptor subunit alpha-1 | Ion channel | IC50 | 5.48 | CHEMBL | |||||
Bile salt export pump | Transporter | IC50 | 4.51 | CHEMBL | |||||
Voltage-dependent T-type calcium channel subunit alpha-1H | Ion channel | Ki | 4.67 | WOMBAT-PK | |||||
Cytochrome P450 1A2 | Enzyme | IC50 | 6.52 | DRUG MATRIX | |||||
Potassium voltage-gated channel subfamily A member 1 | Ion channel | IC50 | 4.02 | CHEMBL | |||||
Voltage-dependent L-type calcium channel subunit alpha-1S | Ion channel | INHIBITOR | IC50 | 6.30 | IUPHAR | ||||
Potassium voltage-gated channel subfamily A member 5 | Ion channel | IC50 | 5.21 | CHEMBL | |||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4A | Enzyme | IC50 | 4.36 | DRUG MATRIX | |||||
Glycine receptor subunit beta | Ion channel | ANTAGONIST | IC50 | 5.90 | IUPHAR | ||||
Potassium voltage-gated channel subfamily A member 2 | Ion channel | Kd | 4.70 | WOMBAT-PK | |||||
Myosin light chain kinase, smooth muscle | Kinase | IC50 | 5.69 | CHEMBL | |||||
Thromboxane-A synthase | Enzyme | IC50 | 4.73 | DRUG MATRIX | |||||
Voltage-dependent L-type calcium channel subunit alpha-1F | Ion channel | GATING INHIBITOR | IC50 | 6 | IUPHAR | ||||
Glycine receptor subunit alpha-3 | Ion channel | ANTAGONIST | IC50 | 4.50 | IUPHAR | ||||
Sodium channel alpha subunits; brain (Types I, II, III) | Ion channel | IC50 | 4.43 | CHEMBL | |||||
C-C chemokine receptor type 2 | GPCR | Ki | 6.07 | DRUG MATRIX | |||||
Sodium/nucleoside cotransporter 1 | Transporter | Ki | 5.09 | DRUG MATRIX | |||||
Arachidonate 15-lipoxygenase | Enzyme | IC50 | 4.82 | DRUG MATRIX | |||||
Adenosine receptor A1 | GPCR | Ki | 5.54 | CHEMBL | |||||
Acetylcholinesterase | Enzyme | Ki | 5.40 | CHEMBL | |||||
Adenosine receptor A2a | GPCR | Ki | 4.74 | CHEMBL | |||||
Voltage-dependent L-type calcium channel subunit alpha-1C | Ion channel | IC50 | 9 | CHEMBL | |||||
Voltage-dependent L-type calcium channel subunit alpha-1C | Ion channel | Ki | 8.46 | CHEMBL | |||||
Voltage-dependent L-type calcium channel subunit alpha-1D | Ion channel | Ki | 8.92 | CHEMBL | |||||
Cholinesterase | Enzyme | Ki | 5.92 | CHEMBL | |||||
Indoleamine 2,3-dioxygenase 2 | Enzyme | IC50 | 5.82 | CHEMBL | |||||
Voltage-dependent L-type calcium channel subunit alpha-1C | Ion channel | IC50 | 8.59 | CHEMBL | |||||
Voltage-gated L-type calcium channel | Ion channel | Ki | 8.33 | CHEMBL | |||||
Indoleamine 2,3-dioxygenase 1 | Enzyme | IC50 | 4.34 | CHEMBL | |||||
Potassium voltage-gated channel subfamily A member 7 | Ion channel | BLOCKER | IC50 | 4.90 | IUPHAR | ||||
Potassium voltage-gated channel subfamily A member 1 | Ion channel | BLOCKER | IC50 | 4 | IUPHAR | ||||
Potassium voltage-gated channel subfamily A member 2 | Ion channel | BLOCKER | Kd | 4.70 | IUPHAR | ||||
Potassium channel subfamily K member 2 | Ion channel | IC50 | 5.09 | CHEMBL | |||||
Bile salt export pump | Transporter | IC50 | 4.34 | CHEMBL |
ID | Source |
---|---|
4018390 | VUID |
N0000146717 | NUI |
D00437 | KEGG_DRUG |
4018390 | VANDF |
C0028066 | UMLSCUI |
CHEBI:7565 | CHEBI |
C5U | PDB_CHEM_ID |
CHEMBL193 | ChEMBL_ID |
DB01115 | DRUGBANK_ID |
D009543 | MESH_DESCRIPTOR_UI |
4485 | PUBCHEM_CID |
2514 | IUPHAR_LIGAND_ID |
3222 | INN_ID |
I9ZF7L6G2L | UNII |
7417 | RXNORM |
2302 | MMSL |
5175 | MMSL |
d00051 | MMSL |
000710 | NDDF |
017700 | NDDF |
387490003 | SNOMEDCT_US |
85272000 | SNOMEDCT_US |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Procardia XL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-2650 | TABLET, FILM COATED, EXTENDED RELEASE | 30 mg | ORAL | NDA | 20 sections |
Procardia XL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-2660 | TABLET, FILM COATED, EXTENDED RELEASE | 60 mg | ORAL | NDA | 20 sections |
Procardia XL | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0069-2670 | TABLET, FILM COATED, EXTENDED RELEASE | 90 mg | ORAL | NDA | 20 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0228-2497 | CAPSULE, LIQUID FILLED | 10 mg | ORAL | ANDA | 19 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0228-2530 | CAPSULE, LIQUID FILLED | 20 mg | ORAL | ANDA | 19 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-7080 | TABLET, EXTENDED RELEASE | 30 mg | ORAL | ANDA | 19 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-7080 | TABLET, EXTENDED RELEASE | 30 mg | ORAL | ANDA | 19 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-7081 | TABLET, EXTENDED RELEASE | 60 mg | ORAL | ANDA | 19 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-7081 | TABLET, EXTENDED RELEASE | 60 mg | ORAL | ANDA | 19 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-7082 | TABLET, EXTENDED RELEASE | 90 mg | ORAL | ANDA | 19 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-7082 | TABLET, EXTENDED RELEASE | 90 mg | ORAL | ANDA | 19 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-7208 | TABLET, EXTENDED RELEASE | 30 mg | ORAL | ANDA | 12 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0904-7229 | CAPSULE | 10 mg | ORAL | ANDA | 19 sections |
NIFEDIPINE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16590-319 | CAPSULE, LIQUID FILLED | 10 mg | ORAL | ANDA | 19 sections |
NIFEDIPINE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 16590-948 | TABLET, FILM COATED, EXTENDED RELEASE | 60 mg | ORAL | ANDA | 11 sections |
nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 21695-807 | TABLET, FILM COATED, EXTENDED RELEASE | 90 mg | ORAL | ANDA | 20 sections |
nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 21695-908 | TABLET, FILM COATED, EXTENDED RELEASE | 30 mg | ORAL | ANDA | 20 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 21695-909 | TABLET, EXTENDED RELEASE | 60 mg | ORAL | ANDA | 14 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 23155-194 | CAPSULE | 10 mg | ORAL | ANDA | 19 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 23155-194 | CAPSULE | 10 mg | ORAL | ANDA | 19 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 23155-195 | CAPSULE | 20 mg | ORAL | ANDA | 19 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 23155-195 | CAPSULE | 20 mg | ORAL | ANDA | 19 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24979-009 | TABLET, EXTENDED RELEASE | 90 mg | ORAL | ANDA | 11 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24979-009 | TABLET, EXTENDED RELEASE | 90 mg | ORAL | ANDA | 11 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24979-009 | TABLET, EXTENDED RELEASE | 90 mg | ORAL | ANDA | 11 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24979-009 | TABLET, EXTENDED RELEASE | 90 mg | ORAL | ANDA | 11 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24979-010 | TABLET, EXTENDED RELEASE | 60 mg | ORAL | ANDA | 11 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24979-010 | TABLET, EXTENDED RELEASE | 60 mg | ORAL | ANDA | 11 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24979-010 | TABLET, EXTENDED RELEASE | 60 mg | ORAL | ANDA | 11 sections |
Nifedipine | HUMAN PRESCRIPTION DRUG LABEL | 1 | 24979-010 | TABLET, EXTENDED RELEASE | 60 mg | ORAL | ANDA | 11 sections |