nicofuranose 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| nicotinic acid or nicotinoyl alcohol derivatives | 1916 | 15351-13-0 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
derivative of nicotinic acid that produces fewer side effects than pure nicotinic acid; used in peripheral vascular disease; also proposed as anticholesteremic; minor descriptor (75-84); on-line search NIACIN/AA (75-84); Index Medicus search NIACIN/AA (83-84), NICOTINIC ACIDS (75-82)
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | C10AD03 | CARDIOVASCULAR SYSTEM LIPID MODIFYING AGENTS LIPID MODIFYING AGENTS, PLAIN Nicotinic acid and derivatives |
| MeSH PA | D002317 | Cardiovascular Agents |
| MeSH PA | D014665 | Vasodilator Agents |
| CHEBI has role | CHEBI:25212 | metabolites |
| CHEBI has role | CHEBI:35620 | vasodilator agents |
| CHEBI has role | CHEBI:35679 | antilipemic drugs |
| CHEBI has role | CHEBI:50247 | antidotes |
| CHEBI has role | CHEBI:75771 | Mus musculus metabolites |
| CHEBI has role | CHEBI:76924 | plant metabolites |
| CHEBI has role | CHEBI:76971 | Escherichia coli metabolites |
| CHEBI has role | CHEBI:84087 | human urinary metabolites |
| CHEBI has role | CHEBI:84264 | nicotinamide deaminase inhibitors |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 9.83 | acidic |
| pKa2 | 3.66 | Basic |
| pKa3 | 3.22 | Basic |
| pKa4 | 2.86 | Basic |
| pKa5 | 2.45 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D07189 | KEGG_DRUG |
| 4017661 | VANDF |
| 4019440 | VANDF |
| C0354652 | UMLSCUI |
| CHEBI:135846 | CHEBI |
| CHEBI:15940 | CHEBI |
| NIO | PDB_CHEM_ID |
| CHEMBL1697844 | ChEMBL_ID |
| DB13422 | DRUGBANK_ID |
| C100123 | MESH_SUPPLEMENTAL_RECORD_UI |
| 1565 | INN_ID |
| GF99P6327K | UNII |
| 25495 | PUBCHEM_CID |
| DB00627 | DRUGBANK_ID |
| 104486 | RXNORM |
| 2275 | MMSL |
| 5169 | MMSL |
| 7161 | MMSL |
| d00314 | MMSL |
| 001052 | NDDF |
| 004010 | NDDF |
| 273943001 | SNOMEDCT_US |
| 319967001 | SNOMEDCT_US |
| 419843007 | SNOMEDCT_US |
| 63639004 | SNOMEDCT_US |
| C0027996 | UMLSCUI |
| 938 | PUBCHEM_CID |
Pharmaceutical products:
None