nandrolone phenpropionate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definition	Drug id	CAS RN
steroids, androgens	1882	62-90-8

Description:

Molecule

Description

Molfile Inchi Smiles

Synonyms:

nandrolone phenpropionate
nandrolon phenylpropionate
nandrolone phenylpropionate
norandrolone phenylpropionate
norandrostenolone phenylpropionate
nortestosterone phenylpropionate

Molecular weight: 406.57
Formula: C27H34O3
CLOGP: 5.93
LIPINSKI: 1
HAC: 3
HDO: 0
TPSA: 43.37
ALOGS: -5.95
ROTB: 5

Status: OFM

Legend:
OFP - off patent
OFM - off market
ONP - on patent

Drug dosage:

None

ADMET properties:

Property	Value	Reference
MRTD (Maximum Recommended Therapeutic Daily Dose)	8.19 µM/kg/day	Contrera JF, Matthews EJ, Kruhlak NL, Benz RD
S (Water solubility)	3.09 mg/mL	Bocci G, Oprea TI, Benet LZ

Approvals:

Date	Agency	Company	Orphan
Oct. 30, 1959	FDA	ORGANON USA INC

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Source	Code	Description
MeSH PA	D045930	Anabolic Agents
MeSH PA	D006728	Hormones
MeSH PA	D000728	Androgens
CHEBI has role	CHEBI:77746	Homo sapiens metabolite
CHEBI has role	CHEBI:50113	androgene
FDA EPC	N0000175824	Androgen

Drug Use | Suggest Off label Use Form| |View source of the data|

None

🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

Target	Class	Pharos	UniProt	Action	Type	Activity value (-log[M])	Mechanism action	Bioact source	MoA source
Androgen receptor	Nuclear hormone receptor	P10275	ANDR_HUMAN	AGONIST	EC50	9.50		WOMBAT-PK	CHEMBL
Estrogen receptor	Nuclear hormone receptor	P03372	ESR1_HUMAN		EC50	6.70		WOMBAT-PK

External reference:

ID	Source
4018518	VUID
N0000179201	NUI
D00956	KEGG_DRUG
4018518	VANDF
4019854	VANDF
C0068397	UMLSCUI
CHEBI:7468	CHEBI
CHEBI:7466	CHEBI
CHEMBL1200412	ChEMBL_ID
DB00984	DRUGBANK_ID
C008580	MESH_SUPPLEMENTAL_RECORD_UI
229455	PUBCHEM_CID
KF7Z9K2T3W	UNII
DB13169	DRUGBANK_ID
31495	RXNORM
2095	MMSL
5153	MMSL
5464	MMSL
d00568	MMSL
001259	NDDF
001261	NDDF
109037003	SNOMEDCT_US
126171003	SNOMEDCT_US
86162003	SNOMEDCT_US
C0027368	UMLSCUI
295	INN_ID
9904	PUBCHEM_CID
D009277	MESH_DESCRIPTOR_UI

Pharmaceutical products:

None