mydecamycin 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| antibiotics, produced by Streptomyces strains | 1861 | 35457-80-8 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
macrolide antibiotic from Streptomyces hygroscopicus JA 6599; structure
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 1.20 | g | O |
| 1 | g | P |
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| MRTD (Maximum Recommended Therapeutic Daily Dose) | 31.59 µM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | J01FA03 | ANTIINFECTIVES FOR SYSTEMIC USE ANTIBACTERIALS FOR SYSTEMIC USE MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS Macrolides |
| MeSH PA | D000900 | Anti-Bacterial Agents |
| MeSH PA | D000890 | Anti-Infective Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 12.8 | acidic |
| pKa2 | 13.95 | acidic |
| pKa3 | 7.88 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D01339 | KEGG_DRUG |
| C0066531 | UMLSCUI |
| CHEBI:31845 | CHEBI |
| CHEMBL1908336 | ChEMBL_ID |
| CHEMBL448615 | ChEMBL_ID |
| C026483 | MESH_SUPPLEMENTAL_RECORD_UI |
| C011138 | MESH_SUPPLEMENTAL_RECORD_UI |
| 5282169 | PUBCHEM_CID |
| DB13456 | DRUGBANK_ID |
| 30005 | RXNORM |
| 005381 | NDDF |
| 703378009 | SNOMEDCT_US |
| 703379001 | SNOMEDCT_US |
| 3461 | INN_ID |
| N34Z0Y5UH7 | UNII |
Pharmaceutical products:
None