mycophenolate mofetil 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |

Stem definitionDrug idCAS RN
1859 128794-94-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • linfonex
  • RS-61443
  • myclausen
  • mycophenolate mofetil
  • mycophenolate mofetil hydrochloride
  • myfenax
  • mycophenolate mofetil HCl
Mycophenolate mofetil is a prodrug of mycophenolic acid, an inhibitor of inosine-5'-monophosphate dehydrogenase. MPA depletes guanosine nucleotides preferentially in T and B lymphocytes and inhibits their proliferation.
  • Molecular weight: 433.50
  • Formula: C23H31NO7
  • CLOGP: 2.78
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 1
  • TPSA: 94.53
  • ALOGS: -3.66
  • ROTB: 10
  • Status: OFP
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

PropertyValueReference
BDDCS (Biopharmaceutical Drug Disposition Classification System) 2 Benet LZ, Broccatelli F, Oprea TI
S (Water solubility) 0.04 mg/mL Benet LZ, Broccatelli F, Oprea TI
EoM (Fraction excreted unchanged in urine) 0 % Benet LZ, Broccatelli F, Oprea TI
MRTD (Maximum Recommended Therapeutic Daily Dose) 47.45 µM/kg/day Contrera JF, Matthews EJ, Kruhlak NL, Benz RD
BA (Bioavailability) 94 %

Predicted pharmacokinetic/toxicological properties (PK-AZ):

PropertyDescriptionValueUnitConfidenceSimilarity
azlogd74 LogD at pH 7.4 2.710 High 1
caco2-efflux Caco-2 efflux ratio (BA/AB) 1.005 High 1
caco2-intrinsic-papp Caco-2 intrinsic apparent permeability 43.652 10^-6 cm/s High 1
dh-clint Dog hepatocyte intrinsic clearance 207.014 uL/min/10^6 cells High 1
dppb Dog plasma protein binding (% unbound) 8.110 % High 1
fcs-ppb Fetal calf serum protein binding (% unbound) 9.660 % High 1
herg hERG pIC50 4.784 pIC50 High 1
hh-clint Human hepatocyte intrinsic clearance 110.662 uL/min/10^6 cells High 1
hlm-clint Human liver microsomal intrinsic clearance 221.309 uL/min/mg protein High 1
hppb Human plasma protein binding (% unbound) 6.050 % High 1
kinase-safety-class ACVR2A,ACVR2B,ACVRL1,AKT2,ALK,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK5,CDK9,DDR1,DYRK1B,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GSK3B,ITK,JAK2,KIT,MAP3K21,MAP3K7,MAPK10,MAPK12,MAPK7,MAPK9,MAPKAPK2,MET,MTOR,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CA,PIK3CB,PIK3CD,PIK3CG,PIM2,PLK1,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TTK,ZAP70 52
kinase-selectivity-class ACVR2B,AXL,BRAF,CDK9,DDR1,EPHB4,FLT3,GRK2,MAP2K6,MAPK7,MARK4,MTOR,PDK4,PRKDC,SIK2,STK33,SYK,TEK,TTK 19
mdck-mdr1-efflux MDCK-MDR1 efflux ratio 2.618 High 1
mh-clint Mouse hepatocyte intrinsic clearance 299.226 High 1
mppb Mouse plasma protein binding (% unbound) 7.190 High 1
nih-mdck-mdr1-efflux NIH MDCK-MDR1 efflux ratio 8.770 High 1
pfas-class PFAS structural alert (1 = True, 0 = False) 0
pld-class Phospholipidosis risk class (1 = positive, 0 = negative) 1 Moderate 0.66
pppb Pig plasma protein binding (% unbound) 19.350 % High 1
rh-clint Rat hepatocyte intrinsic clearance 266.073 uL/min/10^6 cells High 1
rh-fuinc Rat hepatocyte fraction unbound in incubation 64.750 % High 1
rppb Rat plasma protein binding (% unbound) 5.630 % High 1
solubility-dd Solubility at pH 7.4 in DMSO 251.768 uM High 1

Approvals:

DateAgencyCompanyOrphan
June 25, 2021 PMDA CHUGAI PHARMACEUTICAL Co., Ltd
May 3, 1995 FDA ROCHE PALO
Feb. 14, 1998 EMA Roche Registration GmbH

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Transplant rejection 3518.19 10.47 1360 274482 11398 90341207
Cytomegalovirus infection 2867.25 10.47 1467 274375 25135 90327470
Post transplant lymphoproliferative disorder 2016.52 10.47 769 275073 6180 90346425
Off label use 1885.91 10.47 7458 268384 1094794 89257811
Transplant dysfunction 1377.76 10.47 541 275301 4741 90347864
Epstein-Barr virus infection 1304.79 10.47 635 275207 9709 90342896
Thrombotic microangiopathy 1138.05 10.47 667 275175 15076 90337529
Kidney transplant rejection 1136.51 10.47 460 275382 4397 90348208
Product use in unapproved indication 939.10 10.47 2691 273151 333545 90019060
Cytomegalovirus infection reactivation 921.62 10.47 458 275384 7342 90345263
Cytomegalovirus viraemia 909.87 10.47 450 275392 7136 90345469
Polyomavirus-associated nephropathy 792.91 10.47 295 275547 2195 90350410
Fall 791.19 10.47 242 275600 481568 89871037
BK virus infection 753.22 10.47 336 275506 4162 90348443
Acute graft versus host disease 687.55 10.47 335 275507 5133 90347472
Acute graft versus host disease in skin 682.22 10.47 319 275523 4437 90348168
Drug ineffective for unapproved indication 674.77 10.47 920 274922 65724 90286881
Complications of transplanted kidney 671.38 10.47 272 275570 2606 90349999
Posterior reversible encephalopathy syndrome 653.60 10.47 543 275299 21796 90330809
Immunosuppressant drug level increased 628.62 10.47 300 275542 4380 90348225
Smooth muscle cell neoplasm 620.76 10.47 211 275631 1162 90351443
Sciatica 599.04 10.47 1093 274749 100289 90252316
Pain 588.66 10.47 1358 274484 994983 89357622
Varicella zoster virus infection 577.73 10.47 267 275575 3610 90348995
Constipation 523.19 10.47 108 275734 280287 90072318
Chronic graft versus host disease 509.69 10.47 250 275592 3889 90348716
Multiple organ dysfunction syndrome 493.08 10.47 805 275037 67531 90285074
Fatigue 489.89 10.47 1837 274005 1152186 89200419
Pneumocystis jirovecii pneumonia 469.79 10.47 444 275398 21172 90331433
Graft versus host disease in gastrointestinal tract 466.74 10.47 240 275602 4148 90348457
Transplant failure 458.99 10.47 186 275656 1783 90350822
Aspergillus infection 447.48 10.47 323 275519 10500 90342105
Graft versus host disease in skin 436.78 10.47 220 275622 3633 90348972
Trichodysplasia spinulosa 426.51 10.47 135 275707 569 90352036
Nausea 414.20 10.47 1858 273984 1108458 89244147
Injection site pain 413.06 10.47 30 275812 173669 90178936
Polyomavirus viraemia 411.92 10.47 154 275688 1163 90351442
Parvovirus B19 infection 409.76 10.47 143 275699 863 90351742
Graft versus host disease 404.46 10.47 272 275570 7872 90344733
Completed suicide 401.76 10.47 8 275834 145050 90207555
Road traffic accident 401.58 10.47 961 274881 106665 90245940
Diffuse large B-cell lymphoma 401.48 10.47 277 275565 8368 90344237
Epstein-Barr virus associated lymphoproliferative disorder 392.19 10.47 182 275660 2485 90350120
Back pain 389.50 10.47 242 275600 316933 90035672
Cytomegalovirus colitis 379.93 10.47 192 275650 3194 90349411
Renal transplant failure 378.42 10.47 139 275703 993 90351612
Adenovirus infection 371.81 10.47 210 275632 4412 90348193
Nephropathy toxic 368.20 10.47 307 275535 12381 90340224
Product dose omission issue 365.89 10.47 217 275625 291470 90061135
Human herpesvirus 6 infection 362.98 10.47 187 275655 3245 90349360
Klebsiella infection 362.43 10.47 279 275563 10018 90342587
Nocardiosis 358.20 10.47 169 275673 2401 90350204
Ovarian cyst 341.09 10.47 337 275505 16981 90335624
Dyspnoea 340.24 10.47 1454 274388 879501 89473104
Deep vein thrombosis postoperative 335.86 10.47 696 275146 70113 90282492
Autoimmune disorder 332.45 10.47 727 275115 76017 90276588
Histoplasmosis disseminated 331.82 10.47 155 275687 2150 90350455
Liver transplant rejection 331.30 10.47 142 275700 1586 90351019
Heart transplant rejection 324.76 10.47 115 275727 729 90351876
Haemophagocytic lymphohistiocytosis 323.52 10.47 311 275531 15148 90337457
Lupus nephritis 321.20 10.47 194 275648 4638 90347967
Chronic allograft nephropathy 318.03 10.47 112 275730 697 90351908
Lower limb fracture 310.55 10.47 753 275089 84260 90268345
Swollen joint count increased 308.49 10.47 889 274953 110317 90242288
Delayed graft function 306.24 10.47 127 275715 1298 90351307
Headache 306.09 10.47 1469 274373 861277 89491328
Escherichia infection 292.27 10.47 298 275544 15597 90337008
Therapy non-responder 289.19 10.47 995 274847 135709 90216896
Central nervous system lymphoma 285.37 10.47 135 275707 1930 90350675
Chronic graft versus host disease in skin 285.15 10.47 116 275726 1124 90351481
Feeling abnormal 277.63 10.47 82 275760 167153 90185452
Pneumonia cytomegaloviral 276.67 10.47 151 275691 2960 90349645
Bronchopulmonary aspergillosis 276.54 10.47 249 275593 11149 90341456
Hypogammaglobulinaemia 276.52 10.47 242 275600 10432 90342173
JC virus infection 275.64 10.47 144 275698 2575 90350030
Pseudomonas infection 273.88 10.47 279 275563 14586 90338019
Mucormycosis 271.13 10.47 160 275682 3661 90348944
Leukopenia 268.67 10.47 794 275048 99916 90252689
Acne 265.22 10.47 378 275464 28129 90324476
Acute graft versus host disease in intestine 263.03 10.47 128 275714 1955 90350650
Herpes simplex 262.09 10.47 230 275612 9951 90342654
Disease recurrence 256.03 10.47 432 275410 37221 90315384
Cerebral toxoplasmosis 254.76 10.47 111 275731 1294 90351311
Dizziness 248.23 10.47 939 274903 588345 89764260
C-reactive protein 247.48 10.47 385 275457 30982 90321623
Lip dry 245.03 10.47 770 275072 100185 90252420
Aplasia pure red cell 244.90 10.47 168 275674 5026 90347579
Arthralgia 244.75 10.47 1381 274461 777141 89575464
Enterococcal infection 243.85 10.47 219 275623 9772 90342833
Cystitis haemorrhagic 242.80 10.47 171 275671 5342 90347263
Renal impairment 242.16 10.47 789 275053 104632 90247973
Hypotension 240.40 10.47 387 275455 325010 90027595
Hyperhidrosis 237.15 10.47 61 275781 136244 90216361
Injection site erythema 237.06 10.47 16 275826 98486 90254119
Proteinuria 233.30 10.47 320 275522 22971 90329634
Malacoplakia 231.93 10.47 71 275771 261 90352344
Chest discomfort 227.55 10.47 69 275773 138296 90214309
Drug abuse 226.17 10.47 5 275837 82342 90270263
Erythema 225.39 10.47 219 275623 229027 90123578
Liver disorder 224.40 10.47 845 274997 120424 90232181
Cough 217.51 10.47 502 275340 368460 89984145
Septic shock 217.33 10.47 656 275186 83504 90269101
Vaccination failure 217.24 10.47 95 275747 1118 90351487
COVID-19 216.82 10.47 1053 274789 167790 90184815
Epstein-Barr viraemia 215.18 10.47 100 275742 1370 90351235
C-reactive protein abnormal 212.29 10.47 859 274983 126570 90226035
Toxoplasmosis 211.41 10.47 105 275737 1680 90350925
Death 211.16 10.47 699 275143 455852 89896753
Mycobacterial infection 209.74 10.47 112 275730 2098 90350507
Rheumatic fever 209.00 10.47 972 274870 152149 90200456
Progressive multifocal leukoencephalopathy 208.82 10.47 248 275594 15407 90337198
Focal segmental glomerulosclerosis 207.80 10.47 105 275737 1746 90350859
Meningitis cryptococcal 205.84 10.47 104 275738 1729 90350876
Sleep disorder due to general medical condition, insomnia type 205.29 10.47 856 274986 127838 90224767
Joint range of motion decreased 203.07 10.47 885 274957 134758 90217847
Brain abscess 202.81 10.47 119 275723 2693 90349912
Syncope 202.72 10.47 75 275767 132588 90220017
Phaeohyphomycosis 201.90 10.47 70 275772 413 90352192
Infection reactivation 200.26 10.47 104 275738 1836 90350769
Pain in extremity 197.37 10.47 706 275136 449823 89902782
Palpitations 196.34 10.47 85 275757 136643 90215962
Strongyloidiasis 194.97 10.47 96 275746 1506 90351099
Inappropriate schedule of product administration 191.49 10.47 109 275733 149824 90202781
Disseminated cryptococcosis 183.92 10.47 74 275768 695 90351910
Malignant neoplasm progression 181.78 10.47 50 275792 106820 90245785
Graft loss 178.36 10.47 63 275779 396 90352209
Injection site reaction 176.78 10.47 33 275809 92047 90260558
Cryptococcosis 175.61 10.47 87 275755 1384 90351221
Somnolence 173.63 10.47 229 275613 208855 90143750
Dehydration 172.97 10.47 202 275640 194245 90158360
Renal graft infection 169.34 10.47 58 275784 328 90352277
Viraemia 168.07 10.47 88 275754 1581 90351024
Prescribed overdose 164.09 10.47 660 275182 96965 90255640
Chronic obstructive pulmonary disease 163.90 10.47 17 275825 73812 90278793
Intentional overdose 163.20 10.47 42 275800 93792 90258813
Cytomegalovirus chorioretinitis 163.06 10.47 98 275744 2321 90350284
Human polyomavirus infection 161.40 10.47 58 275784 386 90352219
Histoplasmosis 160.88 10.47 94 275748 2110 90350495
Encephalitis viral 160.58 10.47 89 275753 1800 90350805
Viral haemorrhagic cystitis 159.77 10.47 82 275760 1411 90351194
Haemolytic uraemic syndrome 159.37 10.47 102 275740 2709 90349896
Retinitis 158.25 10.47 357 275485 38101 90314504
Loss of consciousness 157.30 10.47 118 275724 140120 90212485
Lupus vulgaris 156.95 10.47 392 275450 44667 90307938
Pathogen resistance 156.25 10.47 156 275686 7959 90344646
Bacteraemia 155.79 10.47 259 275583 22041 90330564
Blood pressure increased 155.72 10.47 224 275618 196993 90155612
Cardiac failure congestive 155.56 10.47 53 275789 98641 90253964
Neuropathy peripheral 153.95 10.47 115 275727 136855 90215750
Nephrotic syndrome 152.34 10.47 147 275695 7192 90345413
Sepsis 149.83 10.47 999 274843 178815 90173790
Flushing 149.38 10.47 42 275800 88449 90264156
Psoriatic arthropathy 149.24 10.47 1197 274645 227138 90125467
Prescribed underdose 149.04 10.47 535 275307 74484 90278121
Balance disorder 148.11 10.47 55 275787 97025 90255580
Adjustment disorder with depressed mood 148.03 10.47 444 275398 56309 90296296
Electrocardiogram QT prolonged 147.89 10.47 22 275820 72434 90280171
Disseminated varicella zoster virus infection 147.84 10.47 55 275787 409 90352196
Pulmonary nocardiosis 147.81 10.47 64 275778 734 90351871
Atypical haemolytic uraemic syndrome 146.88 10.47 68 275774 923 90351682
Injection site swelling 146.12 10.47 9 275833 59830 90292775
Systemic candida 145.98 10.47 121 275721 4838 90347767
Fibromyalgia 145.69 10.47 1101 274741 205168 90147437
Acute respiratory distress syndrome 145.50 10.47 290 275552 28396 90324209
Cerebrovascular accident 145.02 10.47 99 275743 123434 90229171
White blood cell count decreased 144.99 10.47 177 275665 166932 90185673
Type 2 diabetes mellitus 144.19 10.47 1086 274756 202158 90150447
West Nile viral infection 144.16 10.47 56 275786 475 90352130
Therapy partial responder 143.38 10.47 248 275594 21795 90330810
Rash 141.68 10.47 1646 274196 794454 89558151
Overdose 141.15 10.47 163 275679 157546 90195059
Influenza like illness 140.34 10.47 36 275806 80575 90272030
Anti-erythropoietin antibody negative 139.85 10.47 39 275803 93 90352512
Treatment failure 139.72 10.47 1477 274365 302451 90050154
Facet joint syndrome 139.70 10.47 632 275210 97757 90254848
Kidney fibrosis 139.04 10.47 86 275756 2148 90350457
Immunosuppressant drug level decreased 138.75 10.47 69 275773 1107 90351498
Hepatitis E 138.64 10.47 81 275761 1818 90350787
Lung transplant rejection 137.58 10.47 66 275776 975 90351630
Abdominal distension 136.33 10.47 118 275724 130483 90222122
Vision blurred 135.44 10.47 84 275758 110209 90242396
Respiratory failure 135.43 10.47 715 275127 117703 90234902
Human herpesvirus 8 infection 134.37 10.47 49 275793 342 90352263
Acute graft versus host disease in liver 134.28 10.47 60 275782 746 90351859
Drug resistance 133.57 10.47 290 275552 30159 90322446
Microtia 133.16 10.47 49 275793 352 90352253
Swelling face 132.96 10.47 41 275801 81311 90271294
Cytomegalovirus test positive 132.31 10.47 100 275742 3491 90349114
Renal tubular injury 131.93 10.47 68 275774 1181 90351424
Injection site pruritus 131.74 10.47 8 275834 53826 90298779
Myalgia 129.48 10.47 208 275634 174917 90177688
Epstein-Barr virus associated lymphoma 128.59 10.47 56 275786 652 90351953
Hallucination 127.98 10.47 23 275819 65936 90286669
Cytomegalovirus gastrointestinal infection 127.54 10.47 48 275794 370 90352235
Scedosporium infection 126.56 10.47 58 275784 768 90351837
Myocardial infarction 125.63 10.47 84 275758 105888 90246717
Lymphocele 124.42 10.47 57 275785 754 90351851
Injection site bruising 124.39 10.47 9 275833 52298 90300307
Multiple sclerosis relapse 124.38 10.47 9 275833 52296 90300309
Nasal congestion 124.35 10.47 49 275793 83365 90269240
Suicide attempt 123.22 10.47 38 275804 75361 90277244
Dry skin 122.90 10.47 57 275785 88016 90264589
Stress 122.69 10.47 47 275795 81348 90271257
Renal tubular atrophy 122.42 10.47 59 275783 881 90351724
Hypokalaemia 121.17 10.47 132 275710 130984 90221621
Epidermodysplasia verruciformis 121.08 10.47 37 275805 135 90352470
Pneumonia bacterial 119.55 10.47 170 275672 12620 90339985
Renal tubular necrosis 119.50 10.47 182 275660 14373 90338232
Systemic mycosis 118.98 10.47 68 275774 1462 90351143
Graft versus host disease in liver 118.07 10.47 58 275784 905 90351700
Microsporidia infection 117.56 10.47 43 275799 303 90352302
Pulmonary fibrosis 117.42 10.47 641 275201 106862 90245743
Drug effective for unapproved indication 116.60 10.47 132 275710 7786 90344819
Malaise 115.52 10.47 1183 274659 584803 89767802
Venoocclusive liver disease 115.01 10.47 115 275727 5878 90346727
Hyponatraemia 114.19 10.47 143 275699 133395 90219210
Wrong technique in product usage process 113.54 10.47 38 275804 71533 90281072
Rheumatoid factor positive 113.29 10.47 902 274940 170748 90181857
Asthenia 112.55 10.47 1060 274782 532691 89819914
Neutrophil count decreased 110.00 10.47 40 275802 71492 90281113
Wound infection 109.28 10.47 624 275218 105778 90246827
Bone pain 109.21 10.47 27 275815 61956 90290649
Incorrect dose administered 108.72 10.47 52 275790 78878 90273727
Bradycardia 108.41 10.47 60 275782 83787 90268818
Glomerulonephritis 107.35 10.47 76 275766 2394 90350211
Atrial fibrillation 107.18 10.47 150 275692 133461 90219144
Adenoviral hepatitis 106.39 10.47 43 275799 409 90352196
New onset diabetes after transplantation 106.17 10.47 34 275808 150 90352455
Dislocation of vertebra 105.14 10.47 392 275450 55576 90297029
Cognitive disorder 104.74 10.47 40 275802 69367 90283238
Penicillium infection 104.72 10.47 38 275804 261 90352344
Lymphoproliferative disorder 103.18 10.47 93 275749 4169 90348436
Chills 103.08 10.47 151 275691 131830 90220775
Sedation 102.15 10.47 13 275829 48158 90304447
Liver injury 100.64 10.47 874 274968 169693 90182912
Cytomegalovirus oesophagitis 99.38 10.47 40 275802 376 90352229
Haematochezia 98.78 10.47 46 275796 70867 90281738
Injury 98.70 10.47 976 274866 196373 90156232
Bacterial sepsis 98.64 10.47 97 275745 4858 90347747
Bone erosion 98.47 10.47 370 275472 52651 90299954
Cryptosporidiosis infection 98.47 10.47 40 275802 386 90352219
Reversible cerebral vasoconstriction syndrome 97.78 10.47 89 275753 4041 90348564
Lung disorder 96.38 10.47 783 275059 149100 90203505
X-ray abnormal 96.29 10.47 331 275511 45093 90307512
Disseminated aspergillosis 96.04 10.47 41 275801 453 90352152
Chronic graft versus host disease in liver 95.75 10.47 37 275805 309 90352296
Obliterative bronchiolitis 95.13 10.47 73 275769 2608 90349997
Hepatitis C 94.87 10.47 101 275741 5559 90347046
Folliculitis 94.72 10.47 995 274847 203358 90149247
Pulmonary mucormycosis 94.67 10.47 43 275799 557 90352048
Neck pain 94.38 10.47 125 275717 113838 90238767
Oropharyngeal pain 93.71 10.47 128 275714 115059 90237546
Accidental exposure to product 93.41 10.47 10 275832 42356 90310249
Suicidal ideation 92.41 10.47 55 275787 73800 90278805
Neoplasm progression 91.97 10.47 13 275829 44473 90308132
Lupus-like syndrome 90.82 10.47 341 275501 48505 90304100
End stage renal disease 90.76 10.47 121 275721 8450 90344155
Duodenal ulcer perforation 90.45 10.47 1051 274791 220237 90132368
Laryngitis 89.99 10.47 349 275493 50404 90302201
Pre-engraftment immune reaction 89.93 10.47 33 275809 235 90352370
Disseminated mycobacterium avium complex infection 89.45 10.47 33 275809 239 90352366
Unevaluable event 88.98 10.47 28 275814 54820 90297785
Hot flush 88.58 10.47 35 275807 59453 90293152
Inflammation 88.21 10.47 881 274961 177711 90174894
Rash erythematous 87.98 10.47 44 275798 65060 90287545
Dysphonia 87.75 10.47 41 275801 63043 90289562
Rhinorrhoea 87.16 10.47 84 275758 88232 90264373
Orthostatic hypotension 86.99 10.47 12 275830 41815 90310790
Rebound effect 86.64 10.47 124 275718 9260 90343345
Oesophageal atresia 86.49 10.47 41 275801 589 90352016
Macular degeneration 86.23 10.47 8 275834 37962 90314643
Bronchiolitis obliterans syndrome 86.20 10.47 36 275806 375 90352230
Bacillary angiomatosis 85.83 10.47 27 275815 111 90352494
Illness 84.40 10.47 75 275767 81894 90270711
Oedema 83.96 10.47 956 274886 199339 90153266
Donor specific antibody present 83.44 10.47 30 275812 200 90352405
IgA nephropathy 83.09 10.47 45 275797 868 90351737
Hepatic cirrhosis 82.92 10.47 397 275445 62856 90289749
Papilloma viral infection 82.51 10.47 57 275785 1725 90350880
Alternaria infection 82.46 10.47 34 275808 342 90352263
Citrobacter infection 82.38 10.47 41 275801 659 90351946
Lactic acidosis 81.44 10.47 26 275816 50437 90302168
Contraindicated product administered 81.31 10.47 605 275237 319534 90033071
Pneumatosis intestinalis 81.24 10.47 74 275768 3363 90349242
Swollen tongue 81 10.47 20 275822 45936 90306669
Vomiting 80.93 10.47 1806 274036 786487 89566118
Irritable bowel syndrome 80.69 10.47 976 274866 206472 90146133
Emphysematous pyelonephritis 80.64 10.47 33 275809 325 90352280
Hypoglycaemia 80.61 10.47 57 275785 69791 90282814
Vertigo 80.52 10.47 57 275785 69754 90282851
Blood potassium decreased 79.90 10.47 23 275819 47704 90304901
Maternal exposure timing unspecified 79.77 10.47 197 275645 22286 90330319
Tremor 79.60 10.47 222 275620 152951 90199654
Incorrect route of product administration 79.31 10.47 335 275507 50291 90302314
SARS-CoV-2 RNA increased 79.24 10.47 25 275817 104 90352501
Renal phospholipidosis 78.97 10.47 29 275813 207 90352398
Mycoplasma infection 78.23 10.47 43 275799 855 90351750
External auditory canal atresia 77.88 10.47 22 275820 56 90352549
Cardiac disorder 77.51 10.47 38 275804 56834 90295771
Full blood count abnormal 77.30 10.47 10 275832 36587 90316018
Epistaxis 77.20 10.47 87 275755 85038 90267567
Device issue 76.71 10.47 3 275839 29534 90323071
Sinus disorder 76.28 10.47 8 275834 34439 90318166
Pancreas transplant rejection 76.21 10.47 26 275816 145 90352460
Complications of transplanted lung 76.06 10.47 32 275810 340 90352265
Cushingoid 75.66 10.47 123 275719 10272 90342333
Ureaplasma infection 75.18 10.47 42 275800 863 90351742
Glomerulonephritis membranoproliferative 74.48 10.47 31 275811 320 90352285
Graft complication 74.35 10.47 30 275812 284 90352321
Perinephric abscess 74.35 10.47 30 275812 284 90352321
Squamous cell carcinoma of skin 74.08 10.47 102 275740 7347 90345258
Gait inability 73.53 10.47 725 275117 145731 90206874
Helicobacter infection 73.43 10.47 1032 274810 225818 90126787
Agitation 73.25 10.47 58 275784 67040 90285565
Blood iron abnormal 73.23 10.47 75 275767 3945 90348660
Drug level increased 73.14 10.47 218 275624 27544 90325061
Porphyria acute 72.98 10.47 166 275676 17809 90334796
SLE arthritis 72.76 10.47 38 275804 679 90351926
Cytomegalovirus enteritis 72.74 10.47 31 275811 341 90352264
Immune reconstitution inflammatory syndrome 72.66 10.47 98 275744 6921 90345684
Influenza 72.25 10.47 202 275640 139062 90213543
Acute kidney injury 72.23 10.47 1373 274469 319014 90033591
Cytomegalovirus gastritis 71.71 10.47 30 275812 314 90352291
Norovirus infection 71.62 10.47 53 275789 1791 90350814
Chronic graft versus host disease oral 71.53 10.47 27 275815 210 90352395
Steroid diabetes 71.47 10.47 60 275782 2442 90350163
Complications of transplanted heart 71.19 10.47 23 275819 105 90352500
Flatulence 71.00 10.47 19 275823 41348 90311257
Lethargy 70.94 10.47 53 275789 63086 90289519
Cerebral fungal infection 70.73 10.47 28 275814 251 90352354
Symptom masked 70.47 10.47 42 275800 979 90351626
Overlap syndrome 70.34 10.47 107 275735 8441 90344164
Restlessness 70.29 10.47 12 275830 35708 90316897
Exostosis 70.01 10.47 334 275508 52800 90299805
Pulmonary embolism 69.92 10.47 187 275655 130633 90221972
Aspartate aminotransferase increased 69.90 10.47 129 275713 102808 90249797
Cardio-respiratory arrest 69.66 10.47 54 275788 63086 90289519
Pyelonephritis 69.61 10.47 181 275661 21135 90331470
Vasogenic cerebral oedema 68.68 10.47 45 275797 1245 90351360
International normalised ratio increased 68.56 10.47 29 275813 47287 90305318
Drug withdrawal syndrome 68.13 10.47 5 275837 28718 90323887
Breast cancer stage III 67.78 10.47 465 275377 83982 90268623
Visceral leishmaniasis 67.59 10.47 35 275807 614 90351991
Dysgeusia 67.38 10.47 38 275804 52522 90300083
Osteoporosis 67.38 10.47 514 275328 96017 90256588
Anogenital warts 67.36 10.47 34 275808 564 90352041
Humoral immune defect 67.35 10.47 30 275812 370 90352235
Ureteric stenosis 67.33 10.47 36 275806 676 90351929
Necrotising retinitis 67.12 10.47 33 275809 516 90352089
Infection in an immunocompromised host 67.08 10.47 39 275803 867 90351738
Idiopathic pneumonia syndrome 67.01 10.47 31 275811 420 90352185
Blood calcium decreased 66.86 10.47 7 275835 30175 90322430
Gastrooesophageal reflux disease 66.64 10.47 270 275572 166067 90186538
Eye pruritus 66.22 10.47 6 275836 29021 90323584
Mycobacterium abscessus infection 65.93 10.47 41 275801 1034 90351571
Neutrophil Pelger-Huet anomaly present 65.69 10.47 21 275821 92 90352513
Chronic graft versus host disease in eye 65.52 10.47 25 275817 201 90352404
Lymphopenia 65.41 10.47 185 275657 22696 90329909
Red blood cell sedimentation rate increased 65.23 10.47 453 275389 82142 90270463
Enterococcal bacteraemia 65.00 10.47 52 275790 1976 90350629
Dry mouth 64.75 10.47 850 274992 183209 90169396
Locked-in syndrome 64.44 10.47 31 275811 461 90352144
Encephalitis 64.37 10.47 119 275723 11015 90341590
Injection site haemorrhage 64.21 10.47 6 275836 28312 90324293
Lip swelling 63.91 10.47 19 275823 38591 90314014
Serotonin syndrome 63.90 10.47 18 275824 37869 90314736
Eczema 63.88 10.47 41 275801 52829 90299776
Grip strength 63.79 10.47 105 275737 8860 90343745
Atypical mycobacterial infection 63.75 10.47 47 275795 1579 90351026
Human herpesvirus 6 encephalitis 63.28 10.47 29 275813 384 90352221
Gastroenteritis rotavirus 63.26 10.47 25 275817 223 90352382
Infection 63.22 10.47 1495 274347 360599 89992006
COVID-19 pneumonia 63.15 10.47 158 275684 18019 90334586
Muscle injury 63.06 10.47 818 275024 175836 90176769
Pneumocystis jirovecii infection 62.81 10.47 50 275792 1886 90350719
Pneumonia klebsiella 62.76 10.47 61 275781 3011 90349594
Pruritus 62.13 10.47 1218 274624 540307 89812298
Skin exfoliation 62.03 10.47 69 275773 67844 90284761
Oxygen saturation decreased 61.81 10.47 148 275694 107335 90245270
Herpes simplex hepatitis 61.56 10.47 32 275810 566 90352039
Eye irritation 61.44 10.47 14 275828 33964 90318641
Throat irritation 61.29 10.47 36 275806 48659 90303946
Graft versus host disease in lung 61.16 10.47 31 275811 519 90352086
Cryptococcal meningoencephalitis 60.89 10.47 22 275820 149 90352456
Impaired healing 60.66 10.47 1026 274816 233173 90119432
Lacrimation increased 60.66 10.47 6 275836 27056 90325549
Disturbance in attention 60.47 10.47 34 275808 47075 90305530
Body tinea 60.31 10.47 51 275791 2097 90350508
Transient ischaemic attack 60.14 10.47 28 275814 43148 90309457
Blood pressure decreased 60.13 10.47 84 275758 74811 90277794
Presyncope 59.76 10.47 12 275830 31793 90320812
Product quality issue 59.76 10.47 93 275749 79232 90273373
Respiratory arrest 59.68 10.47 14 275828 33297 90319308
Pneumonia fungal 59.26 10.47 89 275753 6942 90345663
Gastrointestinal disorder 59.20 10.47 1104 274738 255583 90097022
Acinetobacter infection 59.11 10.47 49 275793 1959 90350646
Ocular hyperaemia 59.00 10.47 15 275827 33783 90318822
Stenotrophomonas infection 58.90 10.47 54 275788 2475 90350130
Biopsy lung abnormal 58.66 10.47 21 275821 138 90352467
Cystitis viral 58.59 10.47 24 275818 237 90352368
Angina pectoris 58.37 10.47 23 275819 39137 90313468
Full blood count decreased 58.36 10.47 10 275832 29679 90322926
Skin discolouration 58.32 10.47 31 275811 44284 90308321
Agranulocytosis 58.27 10.47 236 275606 34766 90317839
Urinary retention 58.21 10.47 21 275821 37723 90314882
Femur fracture 58.10 10.47 34 275808 46048 90306557
Encephalitis autoimmune 58.06 10.47 49 275793 2009 90350596
Candida infection 57.79 10.47 231 275611 33826 90318779
Micrognathia 57.79 10.47 25 275817 286 90352319
Nervousness 57.77 10.47 16 275826 34040 90318565
Anti-cyclic citrullinated peptide antibody 57.38 10.47 198 275644 27023 90325582
Burning sensation 57.37 10.47 65 275777 63387 90289218
Blood glucose increased 57.31 10.47 128 275714 95118 90257487
Blastomycosis 57.22 10.47 28 275814 433 90352172
Coccidioidomycosis 57.22 10.47 39 275803 1154 90351451
Post transplant distal limb syndrome 56.95 10.47 26 275816 341 90352264
Glomerulosclerosis 56.92 10.47 29 275813 491 90352114
Sneezing 56.69 10.47 11 275831 29858 90322747
Productive cough 56.49 10.47 92 275750 76971 90275634
Cat scratch disease 56.47 10.47 24 275818 262 90352343
Dry eye 56.12 10.47 56 275786 57875 90294730
Depressed level of consciousness 56.11 10.47 84 275758 72700 90279905
Joint injury 56.06 10.47 15 275827 32649 90319956
Dysarthria 55.90 10.47 50 275792 54432 90298173
Gastroenteritis norovirus 55.86 10.47 51 275791 2325 90350280
Unresponsive to stimuli 55.82 10.47 23 275819 38098 90314507
Paraesthesia oral 55.37 10.47 14 275828 31645 90320960
Disseminated cytomegaloviral infection 55.29 10.47 24 275818 277 90352328
Haemoglobin decreased 55.22 10.47 279 275563 161677 90190928
Osteonecrosis of jaw 55.02 10.47 25 275817 39078 90313527
Pulmonary alveolar haemorrhage 55.00 10.47 79 275763 5919 90346686
Retinal vasculitis 54.76 10.47 42 275800 1499 90351106
Red blood cell count decreased 54.58 10.47 37 275805 46314 90306291
Staphylococcal infection 54.34 10.47 291 275551 48148 90304457
Cytomegalovirus duodenitis 54.24 10.47 16 275826 50 90352555
Viral vasculitis 54.22 10.47 18 275824 91 90352514
Depressed mood 54.09 10.47 44 275798 50178 90302427
Limb discomfort 54.08 10.47 24 275818 38036 90314569
Nightmare 53.85 10.47 3 275839 21722 90330883
Periostitis 53.64 10.47 27 275815 445 90352160
Myelitis 53.60 10.47 47 275795 2031 90350574
Encapsulating peritoneal sclerosis 53.56 10.47 25 275817 346 90352259
Product prescribing issue 53.50 10.47 91 275751 7888 90344717
Eye infection toxoplasmal 53.49 10.47 26 275816 396 90352209
Babesiosis 53.26 10.47 23 275819 262 90352343
Restless legs syndrome 53.04 10.47 4 275838 22466 90330139
Heart rate decreased 52.66 10.47 51 275791 53454 90299151
Mycobacterium haemophilum infection 52.59 10.47 21 275821 193 90352412
Epstein-Barr virus infection reactivation 52.52 10.47 42 275800 1595 90351010
Procedural pain 52.41 10.47 18 275824 33342 90319263
Feeling cold 52.37 10.47 10 275832 27455 90325150
Abdominal pain 52.31 10.47 868 274974 394853 89957752
Head injury 52.26 10.47 15 275827 31173 90321432
Microangiopathic haemolytic anaemia 52.17 10.47 32 275810 787 90351818
Drug hypersensitivity 52.17 10.47 1046 274796 462563 89890042
Haemolytic anaemia 51.98 10.47 112 275730 11585 90341020
Injection site mass 51.95 10.47 4 275838 22086 90330519
Swollen joint count 51.94 10.47 94 275748 8559 90344046
Crying 51.84 10.47 8 275834 25637 90326968
Passenger lymphocyte syndrome 51.69 10.47 17 275825 83 90352522
Vesicoureteric reflux 51.54 10.47 23 275819 285 90352320
Human herpesvirus 6 infection reactivation 51.52 10.47 29 275813 605 90352000
Musculoskeletal chest pain 51.36 10.47 6 275836 23744 90328861
Finger deformity 51.25 10.47 18 275824 32879 90319726
Legionella infection 51.22 10.47 27 275815 492 90352113
Mobility decreased 50.94 10.47 1058 274784 249676 90102929
Breast cancer 50.91 10.47 53 275789 53708 90298897
Anaphylactic reaction 50.73 10.47 120 275722 87404 90265201
Urine protein/creatinine ratio increased 50.73 10.47 34 275808 978 90351627
Venoocclusive disease 50.63 10.47 49 275793 2406 90350199
Encephalitis cytomegalovirus 50.62 10.47 30 275812 692 90351913
Pregnancy 50.59 10.47 343 275499 61704 90290901
Cholelithiasis 50.58 10.47 51 275791 52455 90300150
Deep vein thrombosis 50.46 10.47 129 275713 91491 90261114
Blood creatinine increased 50.44 10.47 501 275341 100885 90251720
Steroid dependence 50.04 10.47 47 275795 2222 90350383
Haematemesis 49.95 10.47 20 275822 33706 90318899
Necrotising herpetic retinopathy 49.93 10.47 18 275824 121 90352484
Heart rate increased 49.93 10.47 176 275666 112726 90239879
Skin haemorrhage 49.92 10.47 4 275838 21376 90331229
Peripheral swelling 49.85 10.47 921 274921 412185 89940420
Abortion spontaneous 49.69 10.47 308 275534 53748 90298857
Opportunistic infection 49.47 10.47 46 275796 2147 90350458
Coeliac disease 49.41 10.47 38 275804 44572 90308033
Gingival hypertrophy 49.35 10.47 46 275796 2154 90350451
Pleural mesothelioma malignant 49.24 10.47 15 275827 54 90352551
Bronchial polyp 49.18 10.47 16 275826 75 90352530
Multifocal micronodular pneumocyte hyperplasia 49.18 10.47 16 275826 75 90352530
Intussusception 49.15 10.47 34 275808 1031 90351574
Speech disorder 49.01 10.47 40 275802 45545 90307060
Coloboma 48.93 10.47 17 275825 101 90352504
Epstein-Barr virus test positive 48.81 10.47 29 275813 672 90351933
Cerebral aspergillosis 48.63 10.47 27 275815 548 90352057
Sleep apnoea syndrome 48.39 10.47 18 275824 31729 90320876
Hepatic steatosis 48.39 10.47 26 275816 36919 90315686
Irritability 48.34 10.47 24 275818 35638 90316967
Cytomegalovirus hepatitis 48.26 10.47 24 275818 385 90352220
Central nervous system fungal infection 48.25 10.47 18 275824 135 90352470
Disseminated toxoplasmosis 48.22 10.47 19 275823 168 90352437
Rhodococcus infection 48.14 10.47 18 275824 136 90352469
Mycobacterium chelonae infection 47.90 10.47 28 275814 629 90351976
Apoptosis 47.58 10.47 17 275825 111 90352494
Ill-defined disorder 47.50 10.47 809 275033 184082 90168523
Rash pruritic 47.43 10.47 113 275729 82101 90270504
Joint dislocation 47.43 10.47 264 275578 44318 90308287
Panic attack 47.40 10.47 11 275831 26354 90326251
Tinnitus 47.37 10.47 37 275805 43065 90309540
Intentional product use issue 47.31 10.47 925 274917 215967 90136638
Therapeutic product effect decreased 47.19 10.47 579 275263 276992 90075613
Complications of transplant surgery 47.17 10.47 19 275823 179 90352426
Serositis 47.03 10.47 36 275806 1281 90351324
Night sweats 46.67 10.47 598 275244 128168 90224437
Walking aid user 46.64 10.47 223 275619 35283 90317322
Skin laceration 46.53 10.47 11 275831 26024 90326581
Onychomycosis 46.52 10.47 28 275814 37348 90315257
Rash macular 46.44 10.47 17 275825 30263 90322342
Hypothyroidism 46.34 10.47 56 275786 53071 90299534
Diabetes mellitus 46.14 10.47 347 275495 64528 90288077
Device malfunction 46.12 10.47 5 275837 20972 90331633
Platelet count decreased 46.10 10.47 237 275605 136732 90215873
Apoptotic colonopathy 45.82 10.47 15 275827 72 90352533
Blood glucose decreased 45.82 10.47 8 275834 23421 90329184
Withdrawal syndrome 45.59 10.47 7 275835 22517 90330088
Nephrectomy 45.55 10.47 42 275800 1939 90350666
Tuberculosis gastrointestinal 45.49 10.47 23 275819 383 90352222
Urinary tract infection viral 45.48 10.47 15 275827 74 90352531
Dysplasia 45.22 10.47 36 275806 1358 90351247
Drug level fluctuating 45.18 10.47 25 275817 504 90352101
Orf 45.14 10.47 12 275830 22 90352583
Necrosis 45.14 10.47 76 275766 6534 90346071
Hepatitis B 45.12 10.47 62 275780 4457 90348148
Intentional product misuse 44.97 10.47 132 275710 89472 90263133
Blood sodium decreased 44.96 10.47 14 275828 27599 90325006
Dementia 44.84 10.47 9 275833 23852 90328753
Anaphylactic shock 44.82 10.47 20 275822 31597 90321008
Pneumonia cryptococcal 44.74 10.47 34 275808 1197 90351408
Polyomavirus test positive 44.68 10.47 15 275827 79 90352526
Seasonal allergy 44.61 10.47 8 275834 22975 90329630
Rash maculo-papular 43.91 10.47 36 275806 40897 90311708
Ascites 43.87 10.47 272 275570 47468 90305137
Infected neoplasm 43.85 10.47 22 275820 360 90352245
Evans syndrome 43.74 10.47 22 275820 362 90352243
Hip fracture 43.73 10.47 23 275819 33054 90319551
Plasma cell myeloma 43.68 10.47 36 275806 40792 90311813
Q fever 43.68 10.47 17 275825 145 90352460
Acute myocardial infarction 43.62 10.47 26 275816 34864 90317741
Abdominal discomfort 43.48 10.47 1113 274729 476215 89876390
Angioedema 43.42 10.47 82 275760 64794 90287811
Pallor 43.36 10.47 25 275817 34140 90318465
Fluid retention 43.33 10.47 131 275711 87960 90264645
Affect lability 43.26 10.47 3 275839 18060 90334545
Dysphagia 43.25 10.47 185 275657 112093 90240512
Enterobacter infection 43.13 10.47 46 275796 2537 90350068
Graft thrombosis 43.04 10.47 19 275823 229 90352376
Urinary incontinence 42.89 10.47 31 275811 37535 90315070
Central nervous system infection 42.73 10.47 29 275813 852 90351753
Enterocolitis 42.73 10.47 97 275745 10393 90342212
Human ehrlichiosis 42.72 10.47 18 275824 192 90352413
Haemophilus infection 42.66 10.47 35 275807 1379 90351226
Chronic sinusitis 42.65 10.47 10 275832 23792 90328813
Graft ischaemia 42.64 10.47 15 275827 93 90352512
Urinary tract infection bacterial 42.57 10.47 72 275770 6213 90346392
Grip strength decreased 42.49 10.47 450 275392 92126 90260479
Splenomegaly 42.46 10.47 110 275732 12814 90339791
Oesophagitis ulcerative 42.31 10.47 28 275814 788 90351817
Osteonecrosis 42.16 10.47 175 275667 26066 90326539
Dermatophytosis 42.15 10.47 18 275824 199 90352406
Staphylococcal bacteraemia 42.14 10.47 79 275763 7390 90345215
Disseminated blastomycosis 42.13 10.47 14 275828 71 90352534
Thrombosis 42.00 10.47 101 275741 73150 90279455
Pyelonephritis acute 41.90 10.47 66 275776 5366 90347239
Back injury 41.89 10.47 48 275794 46574 90306031
Hypertelorism 41.83 10.47 24 275818 520 90352085
Squamous cell carcinoma 41.81 10.47 94 275748 10007 90342598
Cytomegalovirus urinary tract infection 41.66 10.47 14 275828 74 90352531
Pleocytosis 41.47 10.47 30 275812 978 90351627
Disseminated strongyloidiasis 41.41 10.47 13 275829 53 90352552
Spinal osteoarthritis 41.01 10.47 5 275837 19143 90333462
Eating disorder 41.00 10.47 17 275825 28056 90324549
Splenic abscess 40.97 10.47 19 275823 259 90352346
Pollakiuria 40.70 10.47 25 275817 32980 90319625
Wheezing 40.60 10.47 980 274862 237100 90115505
Mycobacterium avium complex infection 40.58 10.47 56 275786 4042 90348563
Alveolar proteinosis 40.51 10.47 28 275814 848 90351757
Psoriasis 40.51 10.47 273 275569 147481 90205124
Varicella 40.50 10.47 43 275799 2359 90350246
Nephrolithiasis 40.46 10.47 54 275788 49031 90303574
Acute myeloid leukaemia recurrent 40.45 10.47 40 275802 2017 90350588
Metastatic squamous cell carcinoma 40.39 10.47 19 275823 268 90352337
Engraftment syndrome 40.34 10.47 26 275816 699 90351906
Herpes zoster 40.19 10.47 453 275389 94191 90258414
Reticulocytopenia 40.18 10.47 14 275828 84 90352521
Actinic keratosis 40.06 10.47 49 275793 3139 90349466
Pancytopenia 40.05 10.47 550 275292 119713 90232892
Pneumonia adenoviral 39.92 10.47 18 275824 229 90352376
Sputum discoloured 39.79 10.47 7 275835 20384 90332221
Hepatic fibrosis 39.77 10.47 56 275786 4119 90348486
Toxic epidermal necrolysis 39.61 10.47 25 275817 32503 90320102
Liver abscess 39.57 10.47 51 275791 3445 90349160
Pneumonia acinetobacter 39.50 10.47 14 275828 89 90352516
Surgery 39.48 10.47 47 275795 44840 90307765
Trichophytosis 39.44 10.47 13 275829 64 90352541
Angiosarcoma 39.37 10.47 18 275824 237 90352368
Hiatus hernia 39.30 10.47 14 275828 25347 90327258
Musculoskeletal pain 39.26 10.47 736 275106 170515 90182090
Carpal tunnel syndrome 39.20 10.47 12 275830 23916 90328689
Aggression 39.19 10.47 16 275826 26652 90325953
Fear 39.12 10.47 3 275839 16619 90335986
Urinary tract infection enterococcal 38.94 10.47 47 275795 2969 90349636
Scleroderma 38.84 10.47 69 275773 6192 90346413
Skin fissures 38.79 10.47 8 275834 20801 90331804
Bronchitis 38.78 10.47 289 275553 152638 90199967
Cryptococcal cutaneous infection 38.73 10.47 14 275828 95 90352510
Hypersomnia 38.67 10.47 9 275833 21522 90331083
Neuralgia 38.65 10.47 24 275818 31476 90321129
Cytopenia 38.60 10.47 129 275713 17320 90335285
Renal artery stenosis 38.54 10.47 40 275802 2137 90350468
Chronic myeloid leukaemia 38.53 10.47 44 275798 2620 90349985
Renal tubular disorder 38.22 10.47 48 275794 3159 90349446
Gallbladder disorder 38.21 10.47 7 275835 19796 90332809
Depression 38.19 10.47 664 275178 299937 90052668
Skin graft rejection 38.13 10.47 11 275831 31 90352574
Dyskinesia 38.12 10.47 33 275809 36501 90316104
Remission not achieved 38.00 10.47 17 275825 212 90352393
Muscle spasticity 37.97 10.47 31 275811 35291 90317314
Sinus congestion 37.86 10.47 18 275824 27406 90325199
Respiratory tract congestion 37.83 10.47 18 275824 27392 90325213
Hypocalcaemia 37.66 10.47 44 275798 42324 90310281
Ankle fracture 37.62 10.47 8 275834 20362 90332243
Organising pneumonia 37.56 10.47 76 275766 7521 90345084
Serum sickness 37.50 10.47 50 275792 3492 90349113
Female genital tract fistula 37.46 10.47 5 275837 17863 90334742
Hypoacusis 37.36 10.47 19 275823 27831 90324774
Intervertebral disc protrusion 37.32 10.47 18 275824 27178 90325427
Hypertrichosis 37.24 10.47 33 275809 1446 90351159
Gait disturbance 37.20 10.47 563 275279 259933 90092672
Urate nephropathy 37.18 10.47 15 275827 142 90352463
Sarcoma of skin 37.14 10.47 11 275831 35 90352570
Rheumatoid nodule 37.08 10.47 8 275834 20158 90332447
Mycotic endophthalmitis 37.07 10.47 16 275826 182 90352423
Live birth 37.00 10.47 386 275456 78721 90273884
Upper limb fracture 36.86 10.47 10 275832 21568 90331037
Hypoaesthesia 36.77 10.47 1233 274609 312977 90039628
Interstitial lung disease 36.77 10.47 375 275467 76030 90276575
Complications of transplanted liver 36.69 10.47 20 275822 391 90352214
Superinfection bacterial 36.64 10.47 28 275814 994 90351611
Central nervous system viral infection 36.63 10.47 15 275827 148 90352457
Nasopharyngitis 36.59 10.47 951 274891 406153 89946452
Arteritis infective 36.50 10.47 13 275829 84 90352521
Infection susceptibility increased 36.42 10.47 52 275790 3874 90348731
Listeriosis 36.34 10.47 35 275807 1708 90350897
Tendonitis 36.33 10.47 10 275832 21362 90331243
Acute promyelocytic leukaemia 36.29 10.47 29 275813 1100 90351505
Lymphocytic infiltration 36.13 10.47 29 275813 1107 90351498
Glucose tolerance impaired 36.10 10.47 77 275765 7908 90344697
Amnesia 36.04 10.47 496 275346 108009 90244596
Hospitalisation 35.96 10.47 235 275607 127865 90224740
Xanthoma 35.93 10.47 12 275830 62 90352543
Rhabdomyolysis 35.90 10.47 63 275779 51193 90301412
Delirium 35.87 10.47 480 275362 103879 90248726
Growth retardation 35.67 10.47 35 275807 1748 90350857
Angiocentric lymphoma 35.61 10.47 24 275818 697 90351908
Breath sounds abnormal 35.59 10.47 3 275839 15383 90337222
Inhibitory drug interaction 35.58 10.47 46 275796 3117 90349488
Onychomadesis 35.53 10.47 53 275789 45945 90306660
Product administration error 35.49 10.47 18 275824 26405 90326200
Accidental overdose 35.44 10.47 21 275821 28252 90324353
Pain in jaw 35.43 10.47 57 275785 47928 90304677
Pneumomediastinum 35.39 10.47 37 275805 1994 90350611
Substance-induced psychotic disorder 35.37 10.47 44 275798 2868 90349737
Drug reaction with eosinophilia and systemic symptoms 35.29 10.47 47 275795 42711 90309894
Eye swelling 35.21 10.47 23 275819 29363 90323242
Diarrhoea 35.03 10.47 2425 273417 936765 89415840
Transplant abscess 34.98 10.47 10 275832 27 90352578
Lung neoplasm malignant 34.97 10.47 15 275827 24258 90328347
Rhinovirus infection 34.81 10.47 64 275778 5899 90346706
Muscle twitching 34.80 10.47 15 275827 24187 90328418
Muscle spasms 34.74 10.47 548 275294 251335 90101270
Elbow deformity 34.68 10.47 32 275810 1479 90351126
Disseminated trichosporonosis 34.68 10.47 13 275829 99 90352506
Klebsiella bacteraemia 34.46 10.47 41 275801 2551 90350054
Meningitis herpes 34.45 10.47 17 275825 268 90352337
Alanine aminotransferase increased 34.29 10.47 215 275627 118123 90234482
Breast cancer female 34.17 10.47 3 275839 14883 90337722
Spinal stenosis 33.96 10.47 6 275836 17418 90335187
Arthritis bacterial 33.90 10.47 72 275770 7373 90345232
Dysstasia 33.74 10.47 17 275825 25035 90327570
Peritonitis 33.71 10.47 134 275708 19571 90333034
Neoplasm malignant 33.68 10.47 32 275810 33848 90318757
Cytomegalovirus enterocolitis 33.67 10.47 25 275817 849 90351756
Adrenal mass 33.62 10.47 28 275814 1127 90351478
Musculoskeletal discomfort 33.54 10.47 11 275831 20980 90331625
Mycobacterium fortuitum infection 33.50 10.47 12 275830 79 90352526
Renal cortical necrosis 33.46 10.47 17 275825 286 90352319
Product storage error 33.43 10.47 10 275832 20231 90332374
Escherichia sepsis 33.42 10.47 62 275780 5754 90346851
Graft versus host disease in eye 33.39 10.47 13 275829 111 90352494
Leukaemia in remission 33.35 10.47 9 275833 18 90352587
Vaginal discharge 33.29 10.47 9 275833 19455 90333150
Mucosal inflammation 33.29 10.47 294 275548 57331 90295274
Food allergy 33.26 10.47 18 275824 25460 90327145
Forced vital capacity decreased 33.14 10.47 28 275814 1150 90351455
Movement disorder 33.06 10.47 24 275818 28995 90323610
Foot fracture 33.02 10.47 20 275822 26586 90326019
Hepatitis viral 32.97 10.47 22 275820 628 90351977
Vascular graft complication 32.83 10.47 10 275832 36 90352569
Glomerulonephritis proliferative 32.78 10.47 16 275826 246 90352359
Coordination abnormal 32.73 10.47 12 275830 21344 90331261
Hip arthroplasty 32.46 10.47 365 275477 75843 90276762
Pneumonia influenzal 32.40 10.47 37 275805 2203 90350402
Acute allograft nephropathy 32.38 10.47 8 275834 9 90352596
Fungal skin infection 32.35 10.47 58 275784 5243 90347362
Product dose omission in error 32.32 10.47 11 275831 20492 90332113
Photodermatosis 32.28 10.47 21 275821 574 90352031
Rhinitis allergic 32.24 10.47 6 275836 16779 90335826
Hepatic cyst infection 32.23 10.47 13 275829 123 90352482
Middle insomnia 32.15 10.47 6 275836 16745 90335860
Malacoplakia gastrointestinal 32.15 10.47 11 275831 62 90352543
Parainfluenzae virus infection 31.90 10.47 41 275801 2762 90349843
Lupus pneumonitis 31.83 10.47 12 275830 93 90352512
Laryngeal disorder 31.81 10.47 27 275815 1116 90351489
Renal transplant 31.67 10.47 32 275810 1656 90350949
Sensory loss 31.59 10.47 8 275834 18067 90334538
Escherichia bacteraemia 31.54 10.47 60 275782 5675 90346930
Tooth infection 31.48 10.47 11 275831 20159 90332446
Endocarditis 31.48 10.47 68 275774 7045 90345560
Needle issue 31.47 10.47 3 275839 13931 90338674
Bacterial infection 31.34 10.47 148 275694 23296 90329309
Wrist fracture 31.30 10.47 5 275837 15619 90336986
Therapy interrupted 31.25 10.47 66 275776 50042 90302563
Hypothermia 31.16 10.47 5 275837 15570 90337035
Glycosylated haemoglobin increased 31.13 10.47 5 275837 15557 90337048
Melaena 31.07 10.47 36 275806 34761 90317844
Anaemia 30.94 10.47 827 275015 351975 90000630
Cytomegalovirus gastroenteritis 30.93 10.47 17 275825 338 90352267
Thirst 30.93 10.47 6 275836 16289 90336316
Seizure 30.85 10.47 306 275536 152323 90200282
Haemorrhage intracranial 30.84 10.47 109 275733 15053 90337552
Enterocolitis viral 30.84 10.47 17 275825 340 90352265
Radiculopathy 30.82 10.47 9 275833 18496 90334109
Localised infection 30.76 10.47 34 275808 33528 90319077
Retching 30.69 10.47 10 275832 19149 90333456
Nephritis 30.65 10.47 43 275799 3152 90349453
Abdominal pain lower 30.59 10.47 28 275814 30149 90322456
Ear infection 30.55 10.47 336 275506 69439 90283166
Nematodiasis 30.54 10.47 9 275833 28 90352577
Skin irritation 30.53 10.47 3 275839 13600 90339005
Multiple sclerosis 30.47 10.47 24 275818 27816 90324789
Central nervous system vasculitis 30.46 10.47 26 275816 1083 90351522
Heart rate irregular 30.46 10.47 18 275824 24250 90328355
Seronegative arthritis 30.39 10.47 123 275719 18111 90334494
Proctitis 30.30 10.47 5 275837 15254 90337351
Blood 1,25-dihydroxycholecalciferol increased 30.21 10.47 10 275832 50 90352555
Tooth disorder 30.17 10.47 30 275812 31060 90321545
Oesophageal stenosis 30.13 10.47 47 275795 3789 90348816
Blood test abnormal 30.10 10.47 13 275829 20939 90331666
Oral pain 30.07 10.47 33 275809 32650 90319955
Double stranded DNA antibody positive 30.03 10.47 18 275824 424 90352181
Disseminated mucormycosis 29.98 10.47 21 275821 650 90351955
Skin squamous cell carcinoma metastatic 29.98 10.47 8 275834 15 90352590
Kaposi's sarcoma 29.95 10.47 13 275829 150 90352455
Secretion discharge 29.86 10.47 6 275836 15890 90336715
Meningoencephalitis herpetic 29.86 10.47 29 275813 1430 90351175
Cytomegalovirus mucocutaneous ulcer 29.73 10.47 10 275832 53 90352552
Chronic graft versus host disease in intestine 29.73 10.47 13 275829 153 90352452
Peripheral venous disease 29.67 10.47 388 275454 83533 90269072
Nodular regenerative hyperplasia 29.65 10.47 21 275821 662 90351943
Hypertrophic osteoarthropathy 29.63 10.47 9 275833 32 90352573
Enterovirus infection 29.61 10.47 29 275813 1445 90351160
Varicella zoster pneumonia 29.52 10.47 12 275830 116 90352489
Spinal pain 29.52 10.47 6 275836 15761 90336844
Body temperature increased 29.49 10.47 57 275785 44653 90307952
Chronic kidney disease 29.47 10.47 257 275585 49934 90302671
Lupus vasculitis 29.46 10.47 20 275822 588 90352017
Exposure via partner 29.43 10.47 12 275830 117 90352488
Vaginal haemorrhage 29.41 10.47 31 275811 31240 90321365
Shock haemorrhagic 29.32 10.47 93 275749 12152 90340453
Corynebacterium infection 29.29 10.47 24 275818 944 90351661
Device breakage 29.27 10.47 4 275838 14040 90338565
Abdominal wall infection 29.16 10.47 12 275830 120 90352485
Motor dysfunction 29.15 10.47 11 275831 19219 90333386
Hypoaesthesia oral 29.07 10.47 6 275836 15594 90337011
Musculoskeletal disorder 28.98 10.47 15 275827 21754 90330851
Staphylococcal sepsis 28.93 10.47 78 275764 9305 90343300
Dermatomyositis 28.89 10.47 43 275799 3327 90349278
Cystitis 28.83 10.47 105 275737 66613 90285992
Prophylaxis against transplant rejection 28.80 10.47 9 275833 36 90352569
Proteus infection 28.76 10.47 29 275813 1497 90351108
Septic embolus 28.67 10.47 24 275818 973 90351632
Rib fracture 28.66 10.47 23 275819 26412 90326193
Toothache 28.60 10.47 16 275826 22214 90330391
Colitis erosive 28.53 10.47 14 275828 218 90352387
Pelvic pain 28.43 10.47 6 275836 15351 90337254
Aplastic anaemia 28.39 10.47 97 275745 13172 90339433
Cervical dysplasia 28.37 10.47 47 275795 3987 90348618
Biliary anastomosis complication 28.23 10.47 9 275833 39 90352566
Hypertransaminasaemia 28.19 10.47 109 275733 15716 90336889
Herpes simplex meningitis 28.16 10.47 10 275832 64 90352541
Disseminated tuberculosis 28.14 10.47 42 275800 3257 90349348
Lung diffusion test decreased 28.12 10.47 22 275820 809 90351796
Abnormal behaviour 28.09 10.47 17 275825 22611 90329994
Throat tightness 27.99 10.47 29 275813 29455 90323150
Anorexia nervosa 27.95 10.47 15 275827 284 90352321
Pharyngitis 27.94 10.47 16 275826 21931 90330674
Upper-airway cough syndrome 27.84 10.47 6 275836 15129 90337476
Taste disorder 27.84 10.47 95 275747 61451 90291154
Breast cancer metastatic 27.83 10.47 6 275836 15126 90337479
Escherichia urinary tract infection 27.83 10.47 99 275743 13716 90338889
Hydronephrosis 27.71 10.47 92 275750 12310 90340295
Blood urine present 27.70 10.47 9 275833 17269 90335336
Hypersensitivity 27.70 10.47 1117 274725 453560 89899045
Eye pain 27.69 10.47 58 275784 44110 90308495
Disseminated coccidioidomycosis 27.68 10.47 12 275830 138 90352467
Blood cholesterol increased 27.66 10.47 829 275013 207183 90145422
Cutaneous malacoplakia 27.62 10.47 8 275834 23 90352582
Hypertrophic cardiomyopathy 27.60 10.47 34 275808 2194 90350411
Mydriasis 27.51 10.47 6 275836 15006 90337599
American trypanosomiasis 27.48 10.47 14 275828 237 90352368
Emotional disorder 27.47 10.47 6 275836 14991 90337614
Calciphylaxis 27.41 10.47 42 275800 3334 90349271
Orbital apex syndrome 27.36 10.47 9 275833 44 90352561
Cardiac arrest 27.22 10.47 197 275645 104738 90247867
Condition aggravated 27.13 10.47 2134 273708 593411 89759194
Rheumatic disorder 27.11 10.47 42 275800 3366 90349239
Herpes virus infection 27.08 10.47 60 275782 6324 90346281
Parkinsonism 27.08 10.47 5 275837 14060 90338545
Ejection fraction decreased 27.04 10.47 24 275818 26229 90326376
Actinomycotic sepsis 27.02 10.47 14 275828 246 90352359
Skin burning sensation 26.88 10.47 13 275829 19598 90333007
Paraesthesia 26.86 10.47 569 275273 249757 90102848
Ulcer haemorrhage 26.77 10.47 154 275688 26167 90326438
Disorientation 26.76 10.47 59 275783 44055 90308550
Hepatic necrosis 26.74 10.47 60 275782 6378 90346227
Coronary artery disease 26.70 10.47 38 275804 33585 90319020
Bronchial anastomosis complication 26.69 10.47 10 275832 76 90352529
Myocardial necrosis 26.69 10.47 13 275829 199 90352406
Lysozyme increased 26.63 10.47 7 275835 12 90352593
Mood swings 26.49 10.47 15 275827 20687 90331918
Colon injury 26.47 10.47 14 275828 257 90352348
Pyelonephritis fungal 26.45 10.47 13 275829 203 90352402
Anger 26.15 10.47 5 275837 13715 90338890
Capillaritis 26.11 10.47 12 275830 160 90352445
Sinus tachycardia 26.00 10.47 29 275813 28484 90324121
Intervertebral disc degeneration 25.98 10.47 10 275832 17264 90335341
Paternal exposure during pregnancy 25.94 10.47 15 275827 330 90352275
Acquired plagiocephaly 25.94 10.47 7 275835 14 90352591
Fibromatosis colli of infancy 25.94 10.47 7 275835 14 90352591
Chorioretinitis 25.93 10.47 21 275821 812 90351793
Bursitis 25.89 10.47 553 275289 131101 90221504
Chromaturia 25.87 10.47 13 275829 19174 90333431
Microphthalmos 25.85 10.47 12 275830 164 90352441
Encephalitis enteroviral 25.83 10.47 10 275832 84 90352521
Hypercholesterolaemia 25.73 10.47 441 275401 100451 90252154
Gastroenteritis cryptosporidial 25.72 10.47 10 275832 85 90352520
Cellulitis staphylococcal 25.68 10.47 22 275820 921 90351684
Chronic inflammatory demyelinating polyradiculoneuropathy 25.65 10.47 23 275819 1024 90351581
Urinary tract candidiasis 25.64 10.47 20 275822 732 90351873
Immunosuppression 25.59 10.47 88 275754 11989 90340616
Bile duct stenosis 25.58 10.47 29 275813 1713 90350892
Delayed engraftment 25.57 10.47 11 275831 124 90352481
Product complaint 25.56 10.47 5 275837 13495 90339110
Tooth abscess 25.53 10.47 9 275833 16404 90336201
Blood creatine phosphokinase increased 25.51 10.47 40 275802 33983 90318622
Mediastinitis 25.46 10.47 15 275827 342 90352263
Gastroenteritis viral 25.42 10.47 33 275809 30322 90322283
Alpha haemolytic streptococcal infection 25.42 10.47 29 275813 1725 90350880
Renal artery thrombosis 25.42 10.47 11 275831 126 90352479
Herpes simplex viraemia 25.37 10.47 16 275826 414 90352191
Therapeutic product effect incomplete 25.35 10.47 426 275416 193470 90159135
Fungal infection 25.34 10.47 219 275623 42442 90310163
Hypertension 25.20 10.47 1665 274177 455867 89896738
Breast cancer stage II 25.12 10.47 189 275653 35145 90317460
Candida sepsis 25.10 10.47 28 275814 1625 90350980
Cutaneous blastomycosis 25.01 10.47 7 275835 17 90352588
B-cell lymphoma 25 10.47 42 275800 3604 90349001
Genital herpes simplex 24.99 10.47 16 275826 425 90352180
Troponin increased 24.98 10.47 5 275837 13276 90339329
Arterial occlusive disease 24.89 10.47 4 275838 12442 90340163
Herpes simplex colitis 24.85 10.47 10 275832 94 90352511
Congenital nail disorder 24.85 10.47 10 275832 94 90352511
Gastroenteritis adenovirus 24.75 10.47 14 275828 295 90352310
Ocular hypertension 24.72 10.47 28 275814 1652 90350953
Ageusia 24.69 10.47 9 275833 16067 90336538
Lymphadenitis bacterial 24.68 10.47 8 275834 37 90352568
Arthropathy 24.67 10.47 889 274953 365353 89987252
Ankylosing spondylitis 24.58 10.47 5 275837 13128 90339477
Stevens-Johnson syndrome 24.54 10.47 32 275810 29344 90323261
Haemorrhoids 24.52 10.47 27 275815 26675 90325930
Eosinophilic colitis 24.46 10.47 13 275829 241 90352364
Propionibacterium infection 24.46 10.47 7 275835 19 90352586
Joint stiffness 24.40 10.47 353 275489 77689 90274916
Haemodynamic instability 24.40 10.47 85 275757 11654 90340951
Necrotising fasciitis 24.38 10.47 43 275799 3837 90348768
Poikiloderma 24.37 10.47 14 275828 304 90352301
Erythema multiforme 24.35 10.47 4 275838 12242 90340363
Cystoid macular oedema 24.34 10.47 31 275811 2069 90350536
Microangiopathy 24.25 10.47 28 275814 1687 90350918
Cyst 24.23 10.47 10 275832 16551 90336054
Cholangitis infective 24.22 10.47 16 275826 449 90352156
Tongue necrosis 24.18 10.47 9 275833 67 90352538
Measles 24.13 10.47 15 275827 378 90352227
Tracheo-oesophageal fistula 24.09 10.47 19 275823 707 90351898
Systemic inflammatory response syndrome 24.08 10.47 58 275784 6458 90346147
Germ cell cancer 24.07 10.47 9 275833 68 90352537
Thyroid disorder 24.06 10.47 12 275830 17773 90334832
Fluorosis 24.05 10.47 11 275831 145 90352460
Peptostreptococcus infection 24.04 10.47 10 275832 103 90352502
Secondary immunodeficiency 24.04 10.47 31 275811 2095 90350510
Complications of bone marrow transplant 24.03 10.47 16 275826 455 90352150
Coinfection 24.01 10.47 8 275834 41 90352564
Autoimmune haemolytic anaemia 23.89 10.47 53 275789 5592 90347013
Disseminated intravascular coagulation 23.89 10.47 129 275713 21409 90331196
Renal necrosis 23.84 10.47 9 275833 70 90352535
Head discomfort 23.68 10.47 10 275832 16323 90336282
Type 1 diabetes mellitus 23.63 10.47 48 275794 4764 90347841
Sinus bradycardia 23.60 10.47 11 275831 16941 90335664
Nerve injury 23.54 10.47 3 275839 11103 90341502
Joint swelling 23.53 10.47 1272 274570 502028 89850577
Cholangitis 23.46 10.47 61 275781 7121 90345484
Conjunctivitis 23.45 10.47 28 275814 26678 90325927
Cleft lip and palate 23.41 10.47 19 275823 737 90351868
Myasthenia gravis crisis 23.39 10.47 22 275820 1042 90351563
Infectious pleural effusion 23.24 10.47 29 275813 1896 90350709
Cutaneous nocardiosis 23.20 10.47 9 275833 76 90352529
Parvovirus infection 23.19 10.47 16 275826 483 90352122
Myopathy 23.18 10.47 92 275750 13426 90339179
Stress cardiomyopathy 23.17 10.47 6 275836 13349 90339256
Cytokine storm 23.14 10.47 17 275825 568 90352037
Intestinal obstruction 23.07 10.47 49 275793 37082 90315523
Sensory disturbance 23.06 10.47 9 275833 15404 90337201
Tardive dyskinesia 23.05 10.47 3 275839 10927 90341678
Normocytic anaemia 23.03 10.47 36 275806 2908 90349697
Herpes zoster meningoencephalitis 22.99 10.47 15 275827 412 90352193
Immune recovery uveitis 22.96 10.47 8 275834 48 90352557
Thinking abnormal 22.95 10.47 4 275838 11728 90340877
Feeling jittery 22.95 10.47 9 275833 15362 90337243
Pseudohypoaldosteronism 22.82 10.47 8 275834 49 90352556
Pulmonary vasculitis 22.80 10.47 12 275830 218 90352387
Ligament sprain 22.72 10.47 8 275834 14591 90338014
Tenderness 22.72 10.47 29 275813 26839 90325766
Obesity 22.66 10.47 449 275393 105058 90247547
Hirsutism 22.66 10.47 27 275815 1683 90350922
Systemic scleroderma 22.57 10.47 26 275816 1563 90351042
Weight decreased 22.55 10.47 936 274906 378974 89973631
B-lymphocyte count decreased 22.50 10.47 25 275817 1444 90351161
Pseudomonal bacteraemia 22.43 10.47 29 275813 1965 90350640
Aspergillosis oral 22.42 10.47 8 275834 52 90352553
Hepatitis G 22.42 10.47 9 275833 84 90352521
Peliosis hepatis 22.40 10.47 10 275832 124 90352481
Hyperthyroidism 22.39 10.47 14 275828 18296 90334309
Pharyngeal oedema 22.39 10.47 7 275835 13764 90338841
Dermatitis atopic 22.38 10.47 23 275819 23449 90329156
Tooth extraction 22.36 10.47 4 275838 11509 90341096
Granuloma skin 22.36 10.47 3 275839 10677 90341928
Myocardial calcification 22.32 10.47 12 275830 228 90352377
Oesophageal candidiasis 22.31 10.47 58 275784 6771 90345834
Hyperammonaemia 22.19 10.47 56 275786 6419 90346186
Bladder hypertrophy 22.19 10.47 16 275826 519 90352086
Dyspnoea exertional 22.16 10.47 129 275713 72159 90280446
Groin pain 22.14 10.47 5 275837 12208 90340397
Cytomegalovirus myocarditis 21.92 10.47 8 275834 56 90352549
Disseminated varicella 21.91 10.47 6 275836 13 90352592
Gastrointestinal mucormycosis 21.89 10.47 13 275829 301 90352304
Superinfection viral 21.84 10.47 7 275835 31 90352574
Fracture 21.77 10.47 21 275821 22055 90330550
Blood calcium increased 21.74 10.47 5 275837 12053 90340552
Lipohypertrophy 21.69 10.47 18 275824 721 90351884
Breast pain 21.64 10.47 3 275839 10415 90342190
Glomerulonephritis rapidly progressive 21.59 10.47 23 275819 1267 90351338
Fungal sepsis 21.53 10.47 25 275817 1516 90351089
Cardiac failure 21.51 10.47 221 275621 109275 90243330
Diverticulum oesophageal 21.45 10.47 11 275831 189 90352416
Urosepsis 21.44 10.47 124 275718 21108 90331497
Urinary tract infection pseudomonal 21.43 10.47 20 275822 938 90351667
Encephalopathy 21.42 10.47 226 275616 46218 90306387
Hepatic artery thrombosis 21.36 10.47 9 275833 96 90352509
Osteoarthritis 21.35 10.47 762 275080 194968 90157637
Cleft palate 21.21 10.47 23 275819 1293 90351312
Product preparation error 21.20 10.47 3 275839 10258 90342347
Pulmonary tuberculosis 21.15 10.47 46 275796 4788 90347817
SARS-CoV-2 viraemia 21.15 10.47 7 275835 35 90352570
Liver transplant failure 21.15 10.47 7 275835 35 90352570
Hepatitis B reactivation 21.15 10.47 41 275801 3933 90348672
Pericarditis constrictive 21.08 10.47 16 275826 562 90352043
Infective uveitis 21.06 10.47 5 275837 4 90352601
Creatinine renal clearance decreased 21.05 10.47 16 275826 18883 90333722
Gouty tophus 21.04 10.47 12 275830 257 90352348
Ear discomfort 21.04 10.47 3 275839 10197 90342408
Focal nodular hyperplasia 21 10.47 18 275824 754 90351851
Achromobacter infection 21.00 10.47 8 275834 64 90352541
Pelvic fracture 20.99 10.47 10 275832 15209 90337396
Campylobacter infection 20.98 10.47 22 275820 1190 90351415
Peripheral coldness 20.97 10.47 8 275834 13884 90338721
Face oedema 20.95 10.47 24 275818 23294 90329311
Synovial cyst 20.93 10.47 5 275837 11747 90340858
Limb injury 20.93 10.47 40 275802 31468 90321137
Linear IgA disease 20.92 10.47 30 275812 2244 90350361
Neuropsychiatric lupus 20.89 10.47 11 275831 200 90352405
Body temperature decreased 20.88 10.47 25 275817 23791 90328814
Clostridium difficile colitis 20.80 10.47 146 275696 26560 90326045
Gastric disorder 20.79 10.47 44 275798 33340 90319265
Malacoplakia vesicae 20.79 10.47 8 275834 66 90352539
Renal haemorrhage 20.78 10.47 21 275821 1087 90351518
Polyneuropathy 20.76 10.47 17 275825 19324 90333281
Upper respiratory tract infection bacterial 20.71 10.47 10 275832 150 90352455
Acanthamoeba infection 20.68 10.47 8 275834 67 90352538
Human herpesvirus 7 infection 20.65 10.47 10 275832 151 90352454
Systemic lupus erythematosus 20.64 10.47 1321 274521 360575 89992030
Stomatitis 20.58 10.47 1028 274814 273670 90078935
Renal abscess 20.58 10.47 21 275821 1100 90351505
Viral diarrhoea 20.55 10.47 11 275831 207 90352398
Nail disorder 20.55 10.47 101 275741 58966 90293639
Granulomatous dermatitis 20.55 10.47 11 275831 207 90352398
Haemodialysis 20.55 10.47 66 275776 8681 90343924
Metastases to liver 20.54 10.47 35 275807 28772 90323833
Viral acanthoma 20.54 10.47 5 275837 5 90352600
Renal aneurysm 20.52 10.47 7 275835 39 90352566
Rash papular 20.50 10.47 19 275823 20336 90332269
BK polyomavirus test positive 20.47 10.47 10 275832 154 90352451
Platelet count increased 20.39 10.47 20 275822 20839 90331766
Herpes simplex reactivation 20.38 10.47 20 275822 999 90351606
Sebaceous carcinoma 20.38 10.47 8 275834 70 90352535
Iris coloboma 20.38 10.47 7 275835 40 90352565
Respiratory depression 20.34 10.47 11 275831 15564 90337041
Immunosuppressant drug level 20.28 10.47 6 275836 19 90352586
Nosocomial infection 20.24 10.47 27 275815 1886 90350719
Pneumococcal sepsis 20.22 10.47 19 275823 899 90351706
Blood pressure abnormal 20.19 10.47 18 275824 19627 90332978
Tuberculosis of central nervous system 20.12 10.47 13 275829 351 90352254
Antibody test negative 20.09 10.47 7 275835 42 90352563
Conjunctival melanoma 20.07 10.47 5 275837 6 90352599
Acanthoma 20.07 10.47 5 275837 6 90352599
Palmar-plantar erythrodysaesthesia syndrome 20.03 10.47 34 275808 27989 90324616
Fungal endocarditis 20.02 10.47 13 275829 354 90352251
Dental caries 20.01 10.47 5 275837 11392 90341213
Philadelphia positive chronic myeloid leukaemia 19.95 10.47 7 275835 43 90352562
Meningism 19.94 10.47 15 275827 520 90352085
Foot deformity 19.93 10.47 273 275569 59378 90293227
Arteriovenous fistula occlusion 19.89 10.47 13 275829 358 90352247
Drug level decreased 19.83 10.47 70 275772 9660 90342945
Dysuria 19.80 10.47 58 275784 39343 90313262
Cyanosis 19.78 10.47 18 275824 19437 90333168
Rotator cuff syndrome 19.71 10.47 12 275830 15907 90336698
Abnormal dreams 19.64 10.47 5 275837 11252 90341353
Body mass index abnormal 19.63 10.47 17 275825 722 90351883
Gastric ulcer 19.62 10.47 147 275695 27301 90325304
Granulicatella bacteraemia 19.61 10.47 6 275836 22 90352583
Endocarditis Q fever 19.61 10.47 6 275836 22 90352583
Oral discomfort 19.60 10.47 4 275838 10479 90342126
Skin abrasion 19.58 10.47 5 275837 11230 90341375
Trichosporon infection 19.58 10.47 13 275829 368 90352237
Spinal cord disorder 19.58 10.47 24 275818 1541 90351064
Lymphocyte count decreased 19.56 10.47 49 275793 35001 90317604
Epiglottic erythema 19.53 10.47 8 275834 79 90352526
Adjustment disorder 19.51 10.47 3 275839 9639 90342966
Inflammatory myofibroblastic tumour 19.44 10.47 8 275834 80 90352525
Epstein-Barr virus antigen positive 19.43 10.47 7 275835 47 90352558
Nodule 19.42 10.47 32 275810 26654 90325951
Increased tendency to bruise 19.41 10.47 6 275836 11884 90340721
Tracheobronchitis 19.33 10.47 24 275818 1561 90351044
Haematocrit decreased 19.31 10.47 64 275778 41768 90310837
Bacteriuria 19.30 10.47 21 275821 1185 90351420
Moraxella infection 19.26 10.47 14 275828 460 90352145
Rhesus antigen positive 19.26 10.47 9 275833 125 90352480
Pneumonia aspiration 19.25 10.47 200 275642 40740 90311865
Bullous erysipelas 19.20 10.47 6 275836 24 90352581
Bone marrow transplant rejection 19.18 10.47 8 275834 83 90352522
Blepharospasm 19.18 10.47 95 275747 55350 90297255
Cervicitis 19.14 10.47 15 275827 553 90352052
Craniofacial deformity 19.13 10.47 10 275832 179 90352426
Cholecystectomy 19.07 10.47 6 275836 11749 90340856
Anal incontinence 19.05 10.47 13 275829 16217 90336388
Clostridial sepsis 19.02 10.47 15 275827 558 90352047
Nephrogenic systemic fibrosis 19.02 10.47 40 275802 4068 90348537
Muir-Torre syndrome 19.01 10.47 6 275836 25 90352580
Histoplasmosis cutaneous 19.01 10.47 6 275836 25 90352580
Kidney infection 18.93 10.47 31 275811 25885 90326720
Acute generalised exanthematous pustulosis 18.91 10.47 9 275833 13694 90338911
Eye infection 18.71 10.47 10 275832 14244 90338361
Herpes simplex pneumonia 18.69 10.47 8 275834 89 90352516
Blood loss anaemia 18.69 10.47 4 275838 10136 90342469
Hypertensive crisis 18.63 10.47 16 275826 17768 90334837
Tongue disorder 18.61 10.47 5 275837 10855 90341750
Pulmonary congestion 18.57 10.47 19 275823 19414 90333191
Device occlusion 18.53 10.47 3 275839 9279 90343326
Post herpetic neuralgia 18.51 10.47 31 275811 2653 90349952
Hyperparathyroidism 18.46 10.47 35 275807 3302 90349303
Pulmonary sepsis 18.46 10.47 28 275814 2203 90350402
Spinal fracture 18.37 10.47 24 275818 21992 90330613
Fungaemia 18.36 10.47 35 275807 3315 90349290
Meningoencephalitis bacterial 18.32 10.47 11 275831 260 90352345
Device leakage 18.30 10.47 4 275838 9987 90342618
Tracheal atresia 18.29 10.47 6 275836 29 90352576
Pre-existing condition improved 18.22 10.47 3 275839 9166 90343439
Exposure via skin contact 18.21 10.47 5 275837 10700 90341905
Kaposi sarcoma inflammatory cytokine syndrome 18.21 10.47 5 275837 11 90352594
Subcutaneous abscess 18.18 10.47 53 275789 6613 90345992
Paraspinal abscess 18.17 10.47 11 275831 264 90352341
Viral myelitis 18.13 10.47 6 275836 30 90352575
Perihepatic abscess 18.13 10.47 6 275836 30 90352575
Myopathy toxic 18.11 10.47 15 275827 599 90352006
Therapeutic response unexpected 18.11 10.47 24 275818 21856 90330749
Infusion site pain 18.08 10.47 20 275822 19718 90332887
Feeding disorder 18.05 10.47 16 275826 17496 90335109
Insomnia 18.05 10.47 830 275012 332644 90019961
Haematuria 18.03 10.47 174 275668 34763 90317842
Raoultella ornithinolytica infection 18.01 10.47 8 275834 98 90352507
Product label confusion 17.97 10.47 26 275816 22824 90329781
Biopsy kidney abnormal 17.97 10.47 6 275836 31 90352574
Japanese spotted fever 17.97 10.47 6 275836 31 90352574
Disseminated Bacillus Calmette-Guerin infection 17.96 10.47 7 275835 60 90352545
Demyelinating polyneuropathy 17.94 10.47 18 275824 924 90351681
Bone marrow failure 17.89 10.47 163 275679 32058 90320547
Drug eruption 17.88 10.47 52 275790 35355 90317250
Paternal exposure before pregnancy 17.87 10.47 8 275834 100 90352505
Fryns syndrome 17.76 10.47 7 275835 62 90352543
Granuloma 17.67 10.47 50 275792 6135 90346470
Dermatitis allergic 17.66 10.47 16 275826 17311 90335294
Hyphaema 17.64 10.47 12 275830 354 90352251
Scleroderma renal crisis 17.57 10.47 13 275829 439 90352166
Acid fast bacilli infection 17.52 10.47 8 275834 105 90352500
Acinetobacter bacteraemia 17.52 10.47 8 275834 105 90352500
Faecaloma 17.51 10.47 5 275837 10426 90342179
Blood stem cell transplant failure 17.50 10.47 10 275832 215 90352390
Complication associated with device 17.50 10.47 20 275822 19429 90333176
Pneumonia necrotising 17.43 10.47 15 275827 632 90351973
Intestine transplant rejection 17.37 10.47 7 275835 66 90352539
Pleomorphism 17.36 10.47 5 275837 14 90352591
Engraft failure 17.32 10.47 12 275830 365 90352240
Anuria 17.29 10.47 90 275752 14728 90337877
Neuromyelitis optica spectrum disorder 17.28 10.47 22 275820 1468 90351137
Orbital infection 17.25 10.47 8 275834 109 90352496
Infusion site extravasation 17.24 10.47 5 275837 10323 90342282
Incorrect product administration duration 17.24 10.47 20 275822 19302 90333303
Central nervous system lupus 17.21 10.47 21 275821 1342 90351263
Hallucination, auditory 17.19 10.47 14 275828 15961 90336644
Electrocardiogram abnormal 17.17 10.47 5 275837 10293 90342312
Lung transplant 17.15 10.47 36 275806 3656 90348949
Hydrocephalus 17.15 10.47 49 275793 6045 90346560
Trichostasis spinulosa 17.10 10.47 5 275837 15 90352590
Serratia bacteraemia 17.10 10.47 5 275837 15 90352590
Sleep disorder due to general medical condition, hypersomnia type 17.07 10.47 26 275816 2053 90350552
Therapeutic response shortened 17.06 10.47 27 275815 22852 90329753
Pelvic deformity 17.05 10.47 10 275832 226 90352379
Malignant catatonia 17.05 10.47 10 275832 226 90352379
Obstructive airways disorder 17.04 10.47 33 275809 25836 90326769
Congenital central nervous system anomaly 17.02 10.47 13 275829 461 90352144
Arthritis reactive 17.01 10.47 14 275828 554 90352051
Blood glucose abnormal 16.98 10.47 4 275838 9488 90343117
Emotional distress 16.98 10.47 56 275786 36606 90315999
Congenital diaphragmatic hernia 16.98 10.47 10 275832 228 90352377
Drug ineffective 16.97 10.47 4594 271248 1379704 88972901
Disorder of globe 16.96 10.47 4 275838 3 90352602
Complement fixation abnormal 16.96 10.47 4 275838 3 90352602
Sudden death 16.94 10.47 6 275836 10903 90341702
Acarodermatitis 16.93 10.47 21 275821 1365 90351240
Spinal operation 16.91 10.47 5 275837 10191 90342414
Soft tissue sarcoma 16.88 10.47 9 275833 168 90352437
Bronchospasm 16.85 10.47 23 275819 20686 90331919
Uveitis 16.80 10.47 94 275748 15809 90336796
Soft tissue infection 16.79 10.47 31 275811 2866 90349739
Bacterial pyelonephritis 16.78 10.47 13 275829 471 90352134
Dengue fever 16.74 10.47 17 275825 885 90351720
Tubulointerstitial nephritis 16.60 10.47 133 275709 25210 90327395
Hypophagia 16.57 10.47 55 275787 35882 90316723
Thrombotic thrombocytopenic purpura 16.56 10.47 38 275804 4100 90348505
Antisynthetase syndrome 16.51 10.47 8 275834 121 90352484
Skin mass 16.50 10.47 55 275787 7375 90345230
Vasculitis 16.48 10.47 122 275720 22571 90330034
Hookworm infection 16.43 10.47 4 275838 4 90352601
Fascioliasis 16.43 10.47 4 275838 4 90352601
Erysipelothrix infection 16.43 10.47 4 275838 4 90352601
Reperfusion injury 16.42 10.47 7 275835 77 90352528
Meningitis 16.42 10.47 60 275782 8421 90344184
Renal arteriosclerosis 16.42 10.47 9 275833 178 90352427
Fascial infection 16.41 10.47 5 275837 18 90352587
Psychotic disorder 16.41 10.47 45 275797 31185 90321420
Intentional dose omission 16.31 10.47 18 275824 17765 90334840
Acute respiratory failure 16.26 10.47 201 275641 42717 90309888
Confusional state 16.23 10.47 986 274856 385219 89967386
Pain of skin 16.21 10.47 15 275827 16067 90336538
Mayer-Rokitansky-Kuster-Hauser syndrome 16.20 10.47 5 275837 19 90352586
Pancreas transplant 16.20 10.47 5 275837 19 90352586
Phospholipidosis 16.19 10.47 10 275832 249 90352356
Acute disseminated encephalomyelitis 16.16 10.47 10 275832 250 90352355
Hepatitis cholestatic 16.10 10.47 60 275782 8501 90344104
Enterobacter pneumonia 16.08 10.47 6 275836 45 90352560
Cardiac murmur 16.05 10.47 19 275823 18175 90334430
Perinephric collection 16.05 10.47 8 275834 129 90352476
Colorectal adenocarcinoma 16.02 10.47 9 275833 187 90352418
Aortitis salmonella 16.00 10.47 5 275837 20 90352585
Glomerulonephritis membranous 15.99 10.47 15 275827 708 90351897
Migraine 15.97 10.47 449 275393 189943 90162662
SARS-CoV-2 antibody test negative 15.95 10.47 11 275831 332 90352273
Lung infiltration 15.92 10.47 90 275752 15192 90337413
Transitional cell carcinoma 15.92 10.47 15 275827 712 90351893
Morphoea 15.90 10.47 12 275830 418 90352187
Molluscum contagiosum 15.86 10.47 11 275831 335 90352270
Humerus fracture 15.86 10.47 5 275837 9780 90342825
Cutaneous tuberculosis 15.85 10.47 9 275833 191 90352414
Neurofibrosarcoma 15.85 10.47 9 275833 191 90352414
Injection site induration 15.84 10.47 6 275836 10462 90342143
B-lymphocyte abnormalities 15.81 10.47 10 275832 260 90352345
Hairy cell leukaemia 15.81 10.47 5 275837 21 90352584
Pneumonia pseudomonal 15.79 10.47 32 275810 3171 90349434
Eye discharge 15.76 10.47 3 275839 8255 90344350
Disease progression 15.69 10.47 604 275238 156011 90196594
Diffuse alveolar damage 15.69 10.47 18 275824 1077 90351528
Klebsiella sepsis 15.66 10.47 23 275819 1758 90350847
Ventricular remodelling 15.62 10.47 5 275837 22 90352583
Epstein-Barr virus antibody positive 15.61 10.47 11 275831 344 90352261
Herpes simplex oesophagitis 15.60 10.47 9 275833 197 90352408
Immune thrombocytopenia 15.59 10.47 81 275761 13245 90339360
Thymoma 15.54 10.47 10 275832 268 90352337
Retinal degeneration 15.51 10.47 18 275824 1091 90351514
Haemolysis 15.47 10.47 59 275783 8451 90344154
Colitis 15.47 10.47 299 275543 69643 90282962
Myocardiac abscess 15.45 10.47 5 275837 23 90352582
Upper gastrointestinal haemorrhage 15.41 10.47 29 275813 22947 90329658
Hysterectomy 15.39 10.47 8 275834 11576 90341029
Herpes zoster infection neurological 15.38 10.47 13 275829 534 90352071
Swelling 15.38 10.47 1083 274759 417975 89934630
Encephalitis brain stem 15.37 10.47 8 275834 142 90352463
Infective keratitis 15.33 10.47 6 275836 52 90352553
Epilepsy 15.30 10.47 168 275674 82038 90270567
HCoV-HKU1 infection 15.27 10.47 5 275837 24 90352581
Portal vein embolism 15.25 10.47 7 275835 93 90352512
Ureteral necrosis 15.23 10.47 6 275836 53 90352552
Meningitis tuberculous 15.23 10.47 14 275828 644 90351961
Viral uveitis 15.22 10.47 8 275834 145 90352460
Retinal ischaemia 15.18 10.47 12 275830 448 90352157
Desmoplastic melanoma 15.17 10.47 4 275838 7 90352598
Scopulariopsis infection 15.17 10.47 4 275838 7 90352598
Tuberculous tenosynovitis 15.17 10.47 4 275838 7 90352598
Acanthosis nigricans 15.14 10.47 6 275836 54 90352551
Intensive care unit acquired weakness 15.13 10.47 17 275825 994 90351611
Hepatic haemorrhage 15.08 10.47 14 275828 652 90351953
Salmonella sepsis 15.06 10.47 10 275832 283 90352322
Palatal ulcer 15.05 10.47 9 275833 211 90352394
Photophobia 15.02 10.47 26 275816 21243 90331362
Blood immunoglobulin G increased 15.01 10.47 30 275812 2942 90349663
Pulmonary hypoplasia 15.01 10.47 11 275831 366 90352239
Breast mass 15.01 10.47 5 275837 9442 90343163
Renal tubular acidosis 14.99 10.47 26 275816 2289 90350316
Transient acantholytic dermatosis 14.93 10.47 7 275835 98 90352507
Natural killer-cell leukaemia 14.93 10.47 7 275835 98 90352507
Arteriovenous fistula 14.88 10.47 11 275831 371 90352234
Salmonellosis 14.83 10.47 19 275823 1276 90351329
Parapox virus infection 14.82 10.47 4 275838 8 90352597
Thyroid gland abscess 14.82 10.47 4 275838 8 90352597
Skin squamous cell carcinoma recurrent 14.82 10.47 4 275838 8 90352597
Metastases to bone 14.75 10.47 35 275807 25470 90327135
Post procedural bile leak 14.74 10.47 8 275834 155 90352450
Intracranial infection 14.72 10.47 9 275833 220 90352385
Jaw fracture 14.71 10.47 28 275814 2650 90349955
Injection site discolouration 14.69 10.47 5 275837 9315 90343290
Pterygium colli 14.64 10.47 5 275837 28 90352577
Anxiety 14.62 10.47 782 275060 308990 90043615
Blue toe syndrome 14.60 10.47 12 275830 474 90352131
Pulmonary cavitation 14.60 10.47 17 275825 1034 90351571
Peripheral sensory neuropathy 14.51 10.47 5 275837 9245 90343360
Removal of renal transplant 14.50 10.47 4 275838 9 90352596
Pneumoperitoneum 14.50 10.47 22 275820 1731 90350874
Blood immunoglobulin A decreased 14.47 10.47 22 275820 1734 90350871
Product use issue 14.45 10.47 839 275003 329080 90023525
Mania 14.44 10.47 13 275829 14111 90338494
Quadriparesis 14.43 10.47 27 275815 2522 90350083
Multiple congenital abnormalities 14.40 10.47 13 275829 584 90352021
Ureteral catheterisation 14.39 10.47 3 275839 0 90352605
Metapneumovirus infection 14.37 10.47 19 275823 1316 90351289
Eosinophilia 14.34 10.47 42 275800 28491 90324114
Aphonia 14.28 10.47 10 275832 12309 90340296
Glomerulonephropathy 14.26 10.47 7 275835 109 90352496
Treatment noncompliance 14.25 10.47 229 275613 51498 90301107
Neurotoxicity 14.25 10.47 113 275729 21354 90331251
Tuberculosis of genitourinary system 14.21 10.47 5 275837 31 90352574
Pancreatic enzyme abnormality 14.21 10.47 5 275837 31 90352574
Meningitis histoplasma 14.21 10.47 4 275838 10 90352595
Anomaly of external ear congenital 14.17 10.47 8 275834 168 90352437
Prothrombin time prolonged 14.14 10.47 6 275836 9766 90342839
Jejunal perforation 14.09 10.47 7 275835 112 90352493
Blood potassium increased 14.08 10.47 26 275816 20723 90331882
Psychomotor hyperactivity 14.08 10.47 11 275831 12802 90339803
Febrile bone marrow aplasia 14.06 10.47 6 275836 9732 90342873
Scab 14.02 10.47 6 275836 9715 90342890
Hyperaldosteronism 13.99 10.47 10 275832 320 90352285
Blood immunoglobulin M increased 13.96 10.47 19 275823 1353 90351252
Hypergammaglobulinaemia 13.96 10.47 13 275829 608 90351997
Gastrointestinal stromal tumour 13.95 10.47 19 275823 1354 90351251
Septic arthritis streptococcal 13.94 10.47 4 275838 11 90352594
Stomatococcal infection 13.93 10.47 7 275835 115 90352490
Emphysema 13.92 10.47 10 275832 12145 90340460
Genitourinary tract infection 13.83 10.47 9 275833 246 90352359
Subcutaneous emphysema 13.82 10.47 17 275825 1095 90351510
Diverticulum 13.82 10.47 10 275832 12103 90340502
Tuberculosis 13.81 10.47 75 275767 12474 90340131
Respiratory tract infection fungal 13.77 10.47 12 275830 514 90352091
Disseminated varicella zoster vaccine virus infection 13.77 10.47 6 275836 70 90352535
Eructation 13.76 10.47 8 275834 10874 90341731
Hemianopia homonymous 13.73 10.47 15 275827 850 90351755
Arteriosclerosis coronary artery 13.73 10.47 6 275836 9597 90343008
Chronic cutaneous lupus erythematosus 13.72 10.47 15 275827 851 90351754
Therapeutic product effect variable 13.72 10.47 20 275822 1519 90351086
Jejunal ulcer perforation 13.70 10.47 5 275837 35 90352570
Visceral larva migrans 13.68 10.47 4 275838 12 90352593
Hypoplastic anaemia 13.68 10.47 4 275838 12 90352593
Respiratory papilloma 13.68 10.47 4 275838 12 90352593
Proctalgia 13.63 10.47 4 275838 8194 90344411
Nephropathy 13.61 10.47 60 275782 9175 90343430
Blood iron decreased 13.57 10.47 21 275821 17938 90334667
Hepatocellular injury 13.57 10.47 44 275798 28914 90323691
Eye haemorrhage 13.57 10.47 7 275835 10173 90342432
Vulval ulceration 13.57 10.47 11 275831 426 90352179
Viral load increased 13.55 10.47 20 275822 1536 90351069
Infective aneurysm 13.55 10.47 11 275831 427 90352178
Blood pressure systolic increased 13.51 10.47 113 275729 58232 90294373
Plasma cells decreased 13.46 10.47 5 275837 37 90352568
Fungal abscess central nervous system 13.44 10.47 4 275838 13 90352592
Bartonellosis 13.44 10.47 4 275838 13 90352592
Pseudallescheria infection 13.44 10.47 4 275838 13 90352592
Eosinophil count increased 13.42 10.47 12 275830 13069 90339536
Hyperuricaemia 13.41 10.47 48 275794 6671 90345934
Septal panniculitis 13.40 10.47 6 275836 75 90352530
Plasmapheresis 13.38 10.47 10 275832 343 90352262
Urticaria cholinergic 13.35 10.47 5 275837 38 90352567
Limbal stem cell deficiency 13.35 10.47 5 275837 38 90352567
Post procedural urine leak 13.35 10.47 5 275837 38 90352567
Renal failure 13.30 10.47 506 275336 130501 90222104
T-lymphocyte count decreased 13.28 10.47 10 275832 347 90352258
Hepatic infection bacterial 13.23 10.47 5 275837 39 90352566
Lymphocele marsupialisation 13.22 10.47 4 275838 14 90352591
Ischaemic nephropathy 13.22 10.47 4 275838 14 90352591
Idiopathic interstitial pneumonia 13.21 10.47 9 275833 266 90352339
Eastern Cooperative Oncology Group performance status 13.21 10.47 7 275835 129 90352476
Hypernatraemia 13.21 10.47 6 275836 9381 90343224
Intestinal villi atrophy 13.21 10.47 10 275832 350 90352255
Renal ischaemia 13.19 10.47 13 275829 653 90351952
Ischaemic stroke 13.16 10.47 30 275812 22136 90330469
Gastroenteritis Escherichia coli 13.10 10.47 11 275831 448 90352157
Gastritis 13.07 10.47 74 275768 41679 90310926
Angiosarcoma metastatic 13.05 10.47 6 275836 80 90352525
Iatrogenic infection 13.00 10.47 4 275838 15 90352590
Coxsackie virus test positive 13.00 10.47 4 275838 15 90352590
Gastroenteritis sapovirus 13.00 10.47 4 275838 15 90352590
Graft haemorrhage 13.00 10.47 4 275838 15 90352590
Herpes zoster reactivation 12.96 10.47 8 275834 199 90352406
Transient hypogammaglobulinaemia of infancy 12.91 10.47 5 275837 42 90352563
Neutrophilic dermatosis 12.89 10.47 9 275833 277 90352328
Graft infection 12.89 10.47 9 275833 277 90352328
Subcapsular renal haematoma 12.89 10.47 10 275832 363 90352242
Pericardial effusion 12.89 10.47 170 275672 36663 90315942
Parathyroid hyperplasia 12.88 10.47 7 275835 136 90352469
Blood pressure diastolic abnormal 12.84 10.47 104 275738 19777 90332828
Vitamin D deficiency 12.82 10.47 21 275821 17535 90335070
Tonsillar exudate 12.80 10.47 4 275838 16 90352589
Birdshot chorioretinopathy 12.79 10.47 6 275836 84 90352521
Anosmia 12.79 10.47 7 275835 9841 90342764
Gonorrhoea 12.79 10.47 7 275835 138 90352467
Colitis ulcerative 12.78 10.47 256 275586 60010 90292595
Psychiatric symptom 12.73 10.47 3 275839 7115 90345490
Arrhythmia 12.73 10.47 76 275766 42256 90310349
Oliguria 12.72 10.47 65 275777 10559 90342046
Pharyngitis streptococcal 12.71 10.47 12 275830 12730 90339875
Delusion 12.70 10.47 14 275828 13826 90338779
Abdominal wall abscess 12.67 10.47 16 275826 1059 90351546
Ear malformation 12.64 10.47 9 275833 286 90352319
Renal fusion anomaly 12.61 10.47 4 275838 17 90352588
Tuberous sclerosis complex 12.61 10.47 6 275836 87 90352518
Affective disorder 12.60 10.47 4 275838 7789 90344816
Skin maceration 12.58 10.47 8 275834 210 90352395
Sinusitis 12.56 10.47 1210 274632 341878 90010727
Gastrointestinal haemorrhage 12.54 10.47 196 275646 90052 90262553
Encephalitis Japanese B 12.52 10.47 5 275837 46 90352559
Burkholderia cepacia complex infection 12.51 10.47 8 275834 212 90352393
Hyperthermia 12.50 10.47 8 275834 10327 90342278
Secondary adrenocortical insufficiency 12.44 10.47 24 275818 2294 90350311
Renal amyloidosis 12.43 10.47 9 275833 294 90352311
Tooth fracture 12.41 10.47 12 275830 12588 90340017
Drug tolerance decreased 12.40 10.47 151 275691 31979 90320626
Infusion site erythema 12.36 10.47 14 275828 13656 90338949
Vitamin E deficiency 12.32 10.47 3 275839 3 90352602
Basosquamous carcinoma of skin 12.32 10.47 3 275839 3 90352602
Retroviral infection 12.32 10.47 3 275839 3 90352602
Fibrillary glomerulonephritis 12.32 10.47 3 275839 3 90352602
Nocturia 12.32 10.47 8 275834 10247 90342358
Right atrial hypertrophy 12.32 10.47 3 275839 3 90352602
Vaginal cancer stage 0 12.32 10.47 3 275839 3 90352602
Kidney anastomosis 12.32 10.47 3 275839 3 90352602
Oedematous kidney 12.31 10.47 7 275835 149 90352456
Granulicatella infection 12.31 10.47 7 275835 149 90352456
Accident 12.31 10.47 3 275839 6951 90345654
Vitamin D decreased 12.28 10.47 11 275831 11968 90340637
Mucocutaneous leishmaniasis 12.25 10.47 10 275832 391 90352214
Injection site haematoma 12.22 10.47 3 275839 6919 90345686
Mental impairment 12.21 10.47 20 275822 16700 90335905
Diabetes mellitus inadequate control 12.17 10.47 24 275818 18660 90333945
Dermatofibrosarcoma protuberans 12.15 10.47 5 275837 50 90352555
Optic atrophy 12.09 10.47 19 275823 1542 90351063
Hepatic amoebiasis 12.09 10.47 4 275838 20 90352585
Epigastric discomfort 12.03 10.47 4 275838 7564 90345041
Pancreatic pseudoaneurysm 12.02 10.47 6 275836 97 90352508
Respiratory disorder 12.02 10.47 270 275572 64546 90288059
Knee arthroplasty 12.00 10.47 335 275507 82847 90269758
Squamous cell carcinoma of the cervix 12.00 10.47 10 275832 403 90352202
Dehiscence 11.98 10.47 7 275835 157 90352448
Ultrasound kidney abnormal 11.98 10.47 5 275837 52 90352553
Paranoia 11.91 10.47 13 275829 12895 90339710
Metastases to central nervous system 11.89 10.47 22 275820 17520 90335085
Renal haematoma 11.88 10.47 8 275834 232 90352373
Fat necrosis 11.87 10.47 13 275829 739 90351866
Echinococciasis 11.86 10.47 3 275839 4 90352601
Varicella zoster sepsis 11.86 10.47 3 275839 4 90352601
Complications of transplanted pancreas 11.86 10.47 3 275839 4 90352601
Renal cell carcinoma 11.86 10.47 32 275810 3819 90348786
Catatonia 11.86 10.47 43 275799 6013 90346592
Hypertensive encephalopathy 11.83 10.47 13 275829 742 90351863
Renal cell carcinoma stage I 11.81 10.47 5 275837 54 90352551
Liver function test abnormal 11.81 10.47 219 275623 50626 90301979
Respiratory syncytial virus infection 11.78 10.47 63 275779 10417 90342188
T-lymphocyte count abnormal 11.77 10.47 4 275838 22 90352583
Faeces discoloured 11.75 10.47 30 275812 21290 90331315
Mesothelioma malignant 11.73 10.47 5 275837 55 90352550
Infusion site swelling 11.73 10.47 11 275831 11709 90340896
Hand deformity 11.72 10.47 1051 274791 295311 90057294
Human chorionic gonadotropin decreased 11.70 10.47 6 275836 103 90352502
Central nervous system necrosis 11.68 10.47 7 275835 165 90352440
Parotitis 11.67 10.47 21 275821 1904 90350701
Febrile neutropenia 11.66 10.47 380 275462 157969 90194636
Leukoencephalopathy 11.66 10.47 37 275805 4836 90347769
Lacrimal haemorrhage 11.62 10.47 4 275838 23 90352582
Enterococcal sepsis 11.60 10.47 19 275823 1597 90351008
Splenic vein thrombosis 11.58 10.47 10 275832 423 90352182
Shrinking lung syndrome 11.56 10.47 7 275835 168 90352437
Erythema infectiosum 11.55 10.47 6 275836 106 90352499
Meningitis aseptic 11.54 10.47 46 275796 6727 90345878
Immunoglobulins decreased 11.51 10.47 19 275823 1607 90350998
Bronchostenosis 11.50 10.47 11 275831 532 90352073
Cellulitis 11.50 10.47 202 275640 91135 90261470
Adenovirus reactivation 11.50 10.47 8 275834 245 90352360
C3 glomerulopathy 11.49 10.47 7 275835 170 90352435
Lacrimal gland enlargement 11.48 10.47 4 275838 24 90352581
Choriomeningitis lymphocytic 11.48 10.47 4 275838 24 90352581
Lymphoedema 11.47 10.47 15 275827 13738 90338867
Ureteric obstruction 11.45 10.47 22 275820 2096 90350509
Anal squamous cell carcinoma 11.44 10.47 12 275830 649 90351956
Skin swelling 11.42 10.47 3 275839 6611 90345994
Deafness 11.41 10.47 33 275809 22481 90330124
Foreign body reaction 11.40 10.47 6 275836 109 90352496
Tendon rupture 11.40 10.47 7 275835 9236 90343369
Laryngeal stenosis 11.36 10.47 17 275825 1322 90351283
Gastritis fungal 11.35 10.47 7 275835 174 90352431
Adenoviral haemorrhagic cystitis 11.35 10.47 7 275835 174 90352431
Pseudomonas aeruginosa meningitis 11.34 10.47 4 275838 25 90352580
Nasal oedema 11.34 10.47 3 275839 6581 90346024
Oesophageal achalasia 11.34 10.47 12 275830 656 90351949
Second primary malignancy 11.29 10.47 9 275833 10369 90342236
Abscess bacterial 11.27 10.47 8 275834 253 90352352
Polyserositis 11.26 10.47 12 275830 661 90351944
Brain oedema 11.26 10.47 91 275751 17294 90335311
Bacterial colitis 11.24 10.47 7 275835 177 90352428
Coronary artery occlusion 11.23 10.47 6 275836 8548 90344057
Temperature intolerance 11.23 10.47 12 275830 12018 90340587
Small cell lung cancer recurrent 11.21 10.47 4 275838 26 90352579
Thyroid tuberculosis 11.21 10.47 4 275838 26 90352579
Vasculitic ulcer 11.16 10.47 8 275834 257 90352348
Appetite disorder 11.15 10.47 7 275835 9126 90343479
Anhedonia 11.13 10.47 11 275831 11420 90341185
Skin hypertrophy 11.12 10.47 30 275812 3580 90349025
Meningitis aspergillus 11.12 10.47 3 275839 6 90352599
Bartonella test positive 11.12 10.47 3 275839 6 90352599
Iliac artery perforation 11.12 10.47 3 275839 6 90352599
Viral oesophagitis 11.12 10.47 3 275839 6 90352599
Sinus headache 11.06 10.47 3 275839 6473 90346132
Coagulopathy 11.06 10.47 114 275728 23175 90329430
Fusarium infection 11.04 10.47 15 275827 1067 90351538
Staphylococcal skin infection 11.03 10.47 16 275826 1209 90351396
Pneumonia pneumococcal 11.02 10.47 25 275817 2677 90349928
Guillain-Barre syndrome 11.02 10.47 35 275807 4577 90348028
Activated partial thromboplastin time prolonged 11.01 10.47 5 275837 7820 90344785
Hyperoxaluria 11 10.47 7 275835 184 90352421
Throat cancer 10.99 10.47 13 275829 804 90351801
Oculomotor study abnormal 10.96 10.47 4 275838 28 90352577
Renal vessel disorder 10.96 10.47 4 275838 28 90352577
Hepatic echinococciasis 10.92 10.47 5 275837 66 90352539
Procedural failure 10.92 10.47 5 275837 66 90352539
Wheelchair user 10.92 10.47 5 275837 7780 90344825
Abdominal wound dehiscence 10.90 10.47 8 275834 267 90352338
Lupus myocarditis 10.86 10.47 5 275837 67 90352538
Intestinal tuberculosis 10.84 10.47 6 275836 121 90352484
Genital lesion 10.82 10.47 8 275834 270 90352335
Lupus pleurisy 10.80 10.47 3 275839 7 90352598
Loose associations 10.80 10.47 3 275839 7 90352598
Foetal death 10.78 10.47 30 275812 20693 90331912
Hemivertebra 10.75 10.47 6 275836 123 90352482
Spondylitis 10.74 10.47 77 275765 14101 90338504
Dysmorphism 10.74 10.47 24 275818 2544 90350061
Malignant ascites 10.72 10.47 14 275828 958 90351647
Micturition urgency 10.72 10.47 11 275831 11222 90341383
Vascular pseudoaneurysm 10.70 10.47 19 275823 1704 90350901
Haemorrhage urinary tract 10.67 10.47 15 275827 1102 90351503
Hypomagnesaemia 10.65 10.47 64 275778 35524 90317081
Respiratory tract infection bacterial 10.64 10.47 10 275832 473 90352132
Meningitis enteroviral 10.61 10.47 4 275838 31 90352574
Tender joint count 10.60 10.47 17 275825 1404 90351201
Keratoacanthoma 10.59 10.47 11 275831 588 90352017
Myocardial ischaemia 10.59 10.47 16 275826 13798 90338807
Retinal toxicity 10.59 10.47 17 275825 1405 90351200
Meningitis pneumococcal 10.57 10.47 10 275832 477 90352128
Extrapyramidal disorder 10.57 10.47 21 275821 16282 90336323
Cryptitis 10.54 10.47 5 275837 72 90352533
Pancreatic pseudocyst haemorrhage 10.52 10.47 3 275839 8 90352597
Neurologic neglect syndrome 10.50 10.47 7 275835 8840 90343765
Metastases to spinal cord 10.49 10.47 8 275834 283 90352322
Neuroendocrine carcinoma of the skin 10.48 10.47 13 275829 845 90351760

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Transplant rejection 3467.72 11.57 1490 173326 12098 42434421
Cytomegalovirus infection 3330.57 11.57 1911 172905 30395 42416124
Post transplant lymphoproliferative disorder 1948.04 11.57 883 173933 8237 42438282
Polyomavirus-associated nephropathy 1921.93 11.57 760 174056 4855 42441664
Kidney transplant rejection 1539.09 11.57 739 174077 7944 42438575
Off label use 1339.28 11.57 5648 169168 632687 41813832
BK virus infection 1313.87 11.57 666 174150 8118 42438401
Product use in unapproved indication 1218.68 11.57 2471 172345 181985 42264534
Cytomegalovirus viraemia 1165.52 11.57 650 174166 9727 42436792
Acute graft versus host disease 1073.82 11.57 569 174247 7646 42438873
Complications of transplanted kidney 1054.48 11.57 490 174326 4860 42441659
Epstein-Barr virus infection 987.02 11.57 570 174246 9148 42437371
Adenovirus infection 965.29 11.57 498 174318 6311 42440208
Acute graft versus host disease in skin 958.45 11.57 510 174306 6914 42439605
Cytomegalovirus infection reactivation 933.45 11.57 578 174238 10600 42435919
Thrombotic microangiopathy 859.78 11.57 610 174206 14172 42432347
Transplant dysfunction 840.31 11.57 363 174453 2980 42443539
Immunosuppressant drug level increased 821.35 11.57 467 174349 7264 42439255
Aspergillus infection 801.93 11.57 601 174215 15236 42431283
Graft versus host disease 739.30 11.57 528 174288 12397 42434122
Polyomavirus viraemia 660.62 11.57 268 174548 1844 42444675
Chronic graft versus host disease 653.64 11.57 369 174447 5656 42440863
Fatigue 637.07 11.57 514 174302 435127 42011392
Nocardiosis 629.21 11.57 342 174474 4848 42441671
COVID-19 626.92 11.57 1434 173382 114514 42332005
Graft versus host disease in gastrointestinal tract 596.14 11.57 329 174487 4814 42441705
Graft versus host disease in skin 594.78 11.57 330 174486 4882 42441637
Pneumocystis jirovecii pneumonia 586.29 11.57 615 174201 24566 42421953
Bronchopulmonary aspergillosis 569.72 11.57 538 174278 18891 42427628
Drug ineffective for unapproved indication 566.53 11.57 816 174000 45347 42401172
Parvovirus B19 infection 566.38 11.57 227 174589 1507 42445012
Transplant failure 556.57 11.57 290 174526 3754 42442765
Liver transplant rejection 522.78 11.57 239 174577 2274 42444245
Mucormycosis 520.61 11.57 339 174477 6804 42439715
Phaeohyphomycosis 518.98 11.57 192 174624 992 42445527
Dizziness 511.23 11.57 192 174624 249062 42197457
Chronic allograft nephropathy 510.90 11.57 206 174610 1392 42445127
Nephropathy toxic 493.19 11.57 466 174350 16372 42430147
Fall 488.76 11.57 176 174640 234344 42212175
Acute graft versus host disease in intestine 486.31 11.57 263 174553 3688 42442831
Dyspnoea 455.79 11.57 696 174120 441925 42004594
Pseudomonas infection 446.09 11.57 430 174386 15493 42431026
Heart transplant rejection 436.77 11.57 182 174634 1352 42445167
Klebsiella infection 433.99 11.57 365 174451 10967 42435552
Pain 423.86 11.57 239 174577 244609 42201910
Death 421.88 11.57 810 174006 470375 41976144
Acute respiratory distress syndrome 413.66 11.57 562 174254 29546 42416973
Rash 409.92 11.57 322 174494 276632 42169887
Multiple organ dysfunction syndrome 409.55 11.57 1092 173724 95943 42350576
Constipation 404.63 11.57 86 174730 162205 42284314
Enterococcal infection 396.89 11.57 356 174460 11683 42434836
Drug abuse 394.42 11.57 7 174809 104764 42341755
Cystitis haemorrhagic 393.06 11.57 288 174528 7041 42439478
Cytomegalovirus colitis 389.56 11.57 228 174588 3753 42442766
Disease recurrence 386.71 11.57 540 174276 29138 42417381
Product dose omission issue 384.41 11.57 82 174734 154283 42292236
Nausea 382.75 11.57 651 174165 396148 42050371
Septic shock 379.13 11.57 1024 173792 90648 42355871
Escherichia infection 375.71 11.57 337 174479 11059 42435460
Strongyloidiasis 369.09 11.57 209 174607 3222 42443297
Pruritus 366.24 11.57 158 174658 188613 42257906
Renal transplant failure 363.79 11.57 159 174657 1346 42445173
Cryptococcosis 354.62 11.57 199 174617 3012 42443507
Pulmonary nocardiosis 350.93 11.57 164 174652 1648 42444871
Completed suicide 335.30 11.57 14 174802 96451 42350068
Renal impairment 334.05 11.57 1103 173713 109125 42337394
Malacoplakia 333.41 11.57 130 174686 794 42445725
Delayed graft function 331.56 11.57 178 174638 2457 42444062
Posterior reversible encephalopathy syndrome 328.90 11.57 330 174486 12491 42434028
Chronic graft versus host disease in skin 328.60 11.57 151 174665 1455 42445064
Hepatitis E 326.62 11.57 187 174629 2947 42443572
Human herpesvirus 8 infection 322.84 11.57 146 174670 1351 42445168
COVID-19 pneumonia 322.31 11.57 420 174396 21193 42425326
Focal segmental glomerulosclerosis 306.33 11.57 167 174649 2381 42444138
Brain abscess 304.08 11.57 200 174616 4084 42442435
Diffuse large B-cell lymphoma 300.69 11.57 274 174542 9180 42437339
Asthenia 295.62 11.57 434 174382 280359 42166160
Alternaria infection 293.99 11.57 106 174710 502 42446017
Immunosuppressant drug level decreased 292.36 11.57 145 174671 1679 42444840
Acute graft versus host disease in liver 291.35 11.57 148 174668 1810 42444709
Meningitis cryptococcal 287.35 11.57 175 174641 3108 42443411
Leukopenia 284.27 11.57 810 174006 73936 42372583
JC virus infection 280.70 11.57 167 174649 2837 42443682
Kidney fibrosis 274.56 11.57 159 174657 2563 42443956
Pneumatosis intestinalis 269.08 11.57 193 174623 4559 42441960
Epstein-Barr virus associated lymphoproliferative disorder 265.98 11.57 150 174666 2293 42444226
Varicella zoster virus infection 262.53 11.57 152 174664 2449 42444070
Renal tubular atrophy 261.25 11.57 125 174691 1330 42445189
Lung transplant rejection 260.85 11.57 113 174703 934 42445585
Somnolence 259.72 11.57 127 174689 140978 42305541
Infection reactivation 256.03 11.57 141 174675 2053 42444466
Hypotension 255.95 11.57 414 174402 257217 42189302
Staphylococcal infection 254.15 11.57 510 174306 37133 42409386
Malaise 251.64 11.57 300 174516 211856 42234663
Arthralgia 251.20 11.57 283 174533 204955 42241564
Human herpesvirus 6 infection 248.08 11.57 145 174671 2380 42444139
Respiratory failure 247.95 11.57 1112 173704 127020 42319499
Pain in extremity 247.65 11.57 156 174660 150448 42296071
Haemophagocytic lymphohistiocytosis 243.98 11.57 336 174480 17886 42428633
Aplasia pure red cell 240.33 11.57 214 174602 6952 42439567
Blastomycosis 239.79 11.57 95 174721 609 42445910
Cryptosporidiosis infection 239.74 11.57 98 174718 689 42445830
Pneumonia cytomegaloviral 239.20 11.57 170 174646 3956 42442563
Viraemia 238.04 11.57 125 174691 1645 42444874
Fungal skin infection 234.76 11.57 155 174661 3186 42443333
Renal tubular necrosis 231.69 11.57 329 174487 18025 42428494
Stenotrophomonas infection 227.26 11.57 158 174658 3546 42442973
Epstein-Barr viraemia 226.35 11.57 132 174684 2157 42444362
Proteinuria 226.32 11.57 367 174449 22616 42423903
Renal tubular injury 226.15 11.57 121 174695 1658 42444861
Anxiety 225.40 11.57 102 174714 118458 42328061
Epstein-Barr virus infection reactivation 222.18 11.57 137 174679 2490 42444029
West Nile viral infection 222.03 11.57 97 174719 820 42445699
Back pain 220.77 11.57 156 174660 141620 42304899
Syncope 220.06 11.57 67 174749 99339 42347180
Inappropriate schedule of product administration 218.98 11.57 61 174755 95841 42350678
Histoplasmosis disseminated 218.53 11.57 125 174691 1966 42444553
Candida infection 218.15 11.57 349 174467 21261 42425258
Drug hypersensitivity 216.42 11.57 69 174747 99320 42347199
Graft loss 212.53 11.57 94 174722 821 42445698
Herpes simplex 207.02 11.57 196 174620 6899 42439620
Chest pain 201.32 11.57 166 174650 139364 42307155
Human polyomavirus infection 201.22 11.57 101 174715 1202 42445317
Cytomegalovirus test positive 201.14 11.57 156 174660 4163 42442356
Pulmonary mucormycosis 199.23 11.57 104 174712 1351 42445168
Muscle spasms 197.80 11.57 54 174762 85990 42360529
Venoocclusive liver disease 195.31 11.57 226 174590 10076 42436443
Hyperhidrosis 195.01 11.57 64 174752 90448 42356071
Drug ineffective 193.09 11.57 3637 171179 626560 41819959
Progressive multifocal leukoencephalopathy 192.28 11.57 237 174579 11299 42435220
Urticaria 191.11 11.57 36 174780 74000 42372519
Malignant neoplasm progression 189.85 11.57 104 174712 108296 42338223
Mycobacterium haemophilum infection 189.69 11.57 71 174745 381 42446138
Injection site pain 186.46 11.57 13 174803 57785 42388734
Depression 186.27 11.57 113 174703 111250 42335269
Disseminated cryptococcosis 185.06 11.57 109 174707 1816 42444703
Trichodysplasia spinulosa 184.35 11.57 67 174749 326 42446193
Chronic obstructive pulmonary disease 182.79 11.57 22 174794 63092 42383427
Fungal infection 182.16 11.57 306 174510 19416 42427103
Insomnia 180.30 11.57 133 174683 118120 42328399
Disseminated blastomycosis 179.82 11.57 66 174750 332 42446187
Feeling abnormal 177.86 11.57 35 174781 69751 42376768
Squamous cell carcinoma of skin 176.92 11.57 239 174577 12487 42434032
Myocardial infarction 175.84 11.57 150 174666 123859 42322660
Vomiting 170.51 11.57 613 174203 289110 42157409
Cerebral toxoplasmosis 168.81 11.57 106 174710 1992 42444527
Intentional overdose 167.67 11.57 11 174805 51445 42395074
Monkeypox 166.37 11.57 63 174753 351 42446168
Asthma 165.82 11.57 28 174788 62286 42384233
Blood creatinine increased 165.67 11.57 889 173927 109114 42337405
Peripheral swelling 164.88 11.57 82 174734 90188 42356331
Treatment failure 163.69 11.57 597 174219 62027 42384492
Nasopharyngitis 163.18 11.57 70 174746 83926 42362593
Vaccination failure 161.93 11.57 91 174725 1381 42445138
Histoplasmosis 158.31 11.57 96 174720 1691 42444828
Encephalitis viral 156.09 11.57 90 174726 1438 42445081
Viral haemorrhagic cystitis 155.05 11.57 96 174720 1758 42444761
Cardiac failure congestive 154.48 11.57 79 174737 85523 42360996
Disseminated tuberculosis 153.74 11.57 112 174704 2712 42443807
Hypogammaglobulinaemia 152.80 11.57 215 174601 11676 42434843
Lymphopenia 151.35 11.57 297 174519 21266 42425253
Bradycardia 151.14 11.57 81 174735 85403 42361116
Complications of transplanted heart 149.79 11.57 55 174761 277 42446242
Complications of transplanted lung 148.99 11.57 55 174761 282 42446237
Hypoglycaemia 148.43 11.57 32 174784 59822 42386697
Psoriasis 148.27 11.57 14 174802 48590 42397929
Papilloma viral infection 148.08 11.57 68 174748 654 42445865
Enterobacter infection 147.55 11.57 112 174704 2892 42443627
Toxoplasmosis 146.67 11.57 88 174728 1519 42445000
Neutrophil Pelger-Huet anomaly present 145.80 11.57 51 174765 217 42446302
Drug level increased 145.61 11.57 328 174488 25872 42420647
Stress 145.40 11.57 9 174807 44203 42402316
Chronic graft versus host disease in liver 145.07 11.57 66 174750 620 42445899
Cat scratch disease 142.14 11.57 54 174762 304 42446215
Hepatitis C 141.92 11.57 191 174625 9942 42436577
Decreased appetite 141.01 11.57 370 174446 192767 42253752
Gingival hypertrophy 140.25 11.57 100 174716 2339 42444180
Bacillary angiomatosis 139.70 11.57 47 174769 173 42446346
Pneumocystis jirovecii infection 139.09 11.57 106 174710 2754 42443765
Mycobacterium chelonae infection 138.27 11.57 76 174740 1102 42445417
Renal graft infection 137.65 11.57 54 174762 336 42446183
Atrial fibrillation 135.89 11.57 227 174589 139366 42307153
Drug resistance 133.85 11.57 375 174441 33873 42412646
Suicide attempt 133.66 11.57 16 174800 46084 42400435
Mycobacterial infection 132.21 11.57 100 174716 2568 42443951
Hypersensitivity 131.75 11.57 66 174750 72304 42374215
Platelet count decreased 131.55 11.57 229 174587 138352 42308167
Scedosporium infection 131.12 11.57 81 174735 1477 42445042
Graft versus host disease in lung 130.47 11.57 63 174753 685 42445834
Drug reaction with eosinophilia and systemic symptoms 128.66 11.57 12 174804 42063 42404456
Wheezing 128.49 11.57 33 174783 54748 42391771
End stage renal disease 128.46 11.57 238 174578 16320 42430199
Wrong technique in product usage process 128.16 11.57 13 174803 42622 42403897
Headache 126.88 11.57 528 174288 238841 42207678
Actinic keratosis 126.84 11.57 130 174686 5046 42441473
IgA nephropathy 126.63 11.57 93 174723 2281 42444238
Cytomegalovirus chorioretinitis 126.24 11.57 123 174693 4488 42442031
Sleep disorder 124.93 11.57 23 174793 48072 42398447
Glomerulonephritis 124.56 11.57 95 174721 2471 42444048
Loss of consciousness 124.54 11.57 117 174699 92237 42354282
Rebound effect 123.62 11.57 152 174664 7227 42439292
Lymphoproliferative disorder 123.48 11.57 105 174711 3202 42443317
Graft complication 123.18 11.57 60 174756 666 42445853
Suicidal ideation 123.04 11.57 24 174792 48137 42398382
Neutrophil count decreased 122.92 11.57 53 174763 63362 42383157
White blood cell count decreased 122.48 11.57 164 174652 110232 42336287
Joint swelling 122.38 11.57 63 174753 67959 42378560
Pulmonary embolism 121.58 11.57 189 174627 119423 42327096
Lymphocele 121.56 11.57 77 174739 1470 42445049
Dry skin 119.53 11.57 26 174790 48312 42398207
Smooth muscle cell neoplasm 119.09 11.57 45 174771 249 42446270
International normalised ratio increased 118.92 11.57 26 174790 48142 42398377
Bacteraemia 118.02 11.57 294 174522 24746 42421773
Graft versus host disease in liver 117.49 11.57 77 174739 1562 42444957
Systemic mycosis 117.25 11.57 89 174727 2298 42444221
Loss of personal independence in daily activities 116.86 11.57 30 174786 49786 42396733
Confusional state 113.42 11.57 333 174483 167264 42279255
Hypoaesthesia 113.32 11.57 77 174739 71386 42375133
Organising pneumonia 113.24 11.57 147 174669 7385 42439134
Disseminated varicella zoster virus infection 113.19 11.57 58 174758 723 42445796
Therapy non-responder 112.90 11.57 476 174340 52883 42393636
Neurotoxicity 112.85 11.57 279 174537 23372 42423147
Endophthalmitis 111.65 11.57 113 174703 4320 42442199
Alveolar proteinosis 111.01 11.57 56 174760 674 42445845
Dermatophytosis 110.63 11.57 43 174773 260 42446259
Demodicidosis 110.50 11.57 40 174776 192 42446327
Intentional product misuse 110.37 11.57 58 174758 61842 42384677
Pathogen resistance 110.21 11.57 181 174635 11269 42435250
Overdose 110.18 11.57 163 174653 105101 42341418
Epstein-Barr virus associated lymphoma 106.80 11.57 62 174754 1004 42445515
Blood pressure increased 106.52 11.57 158 174658 101770 42344749
General physical health deterioration 105.64 11.57 296 174520 150950 42295569
Mycoplasma infection 105.53 11.57 52 174764 593 42445926
Gait disturbance 105.27 11.57 149 174667 97851 42348668
Angiosarcoma 105.10 11.57 44 174772 331 42446188
Acinetobacter infection 105.08 11.57 70 174746 1461 42445058
Drug interaction 104.01 11.57 1604 173212 265395 42181124
Mycetoma mycotic 103.57 11.57 43 174773 316 42446203
Palpitations 102.42 11.57 40 174776 50757 42395762
Atypical mycobacterial infection 102.40 11.57 66 174750 1300 42445219
Nephrotic syndrome 102.31 11.57 151 174665 8567 42437952
Gastroenteritis norovirus 102.21 11.57 72 174744 1651 42444868
Paraesthesia 101.48 11.57 91 174725 73368 42373151
Squamous cell carcinoma 101.20 11.57 187 174629 12795 42433724
Penicillium infection 100.93 11.57 41 174775 283 42446236
Musculoskeletal stiffness 100.25 11.57 56 174760 57709 42388810
Pneumonia klebsiella 99.64 11.57 104 174712 4125 42442394
Balance disorder 98.60 11.57 36 174780 47609 42398910
Pancreas transplant rejection 98.42 11.57 36 174780 179 42446340
Rhodococcus infection 97.87 11.57 41 174775 309 42446210
Chest discomfort 97.62 11.57 71 174745 63545 42382974
Cerebrovascular accident 97.31 11.57 155 174661 97005 42349514
Cytomegalovirus gastrointestinal infection 97.31 11.57 41 174775 314 42446205
Dehydration 97.12 11.57 280 174536 141487 42305032
Norovirus infection 97.02 11.57 52 174764 715 42445804
Malacoplakia gastrointestinal 96.59 11.57 34 174782 148 42446371
Pneumonia cryptococcal 96.45 11.57 66 174750 1442 42445077
Obliterative bronchiolitis 95.96 11.57 65 174751 1396 42445123
Pneumonia fungal 95.44 11.57 150 174666 8996 42437523
Trichophytosis 95.43 11.57 42 174774 362 42446157
Ureteric stenosis 95.02 11.57 61 174755 1193 42445326
Electrocardiogram QT prolonged 94.63 11.57 39 174777 47906 42398613
Agitation 94.57 11.57 75 174741 64239 42382280
Pyelonephritis 94.21 11.57 138 174678 7776 42438743
Hydronephrosis 93.86 11.57 172 174644 11693 42434826
Oedema peripheral 93.77 11.57 268 174548 135808 42310711
Idiopathic pneumonia syndrome 93.72 11.57 44 174772 447 42446072
Haemolytic uraemic syndrome 93.15 11.57 79 174737 2400 42444119
Human ehrlichiosis 92.29 11.57 44 174772 464 42446055
Cytomegalovirus oesophagitis 92.26 11.57 46 174770 539 42445980
Bacterial sepsis 92.02 11.57 123 174693 6359 42440160
Mycobacterium abscessus infection 91.88 11.57 50 174766 710 42445809
C3 glomerulopathy 91.51 11.57 32 174784 136 42446383
Ureaplasma infection 91.51 11.57 47 174769 589 42445930
Epistaxis 90.86 11.57 84 174732 66742 42379777
Skin papilloma 90.84 11.57 82 174734 2712 42443807
Aggression 90.32 11.57 34 174782 44129 42402390
Full blood count abnormal 90.08 11.57 9 174807 29867 42416652
Pancytopenia 90.07 11.57 806 174010 116937 42329582
Erythema 89.98 11.57 195 174621 108598 42337921
Choroiditis 89.89 11.57 61 174755 1314 42445205
Angiosarcoma metastatic 89.85 11.57 28 174788 75 42446444
Encephalitis 89.81 11.57 146 174670 9012 42437507
Thrombosis 89.78 11.57 89 174727 68422 42378097
Blood glucose increased 89.59 11.57 102 174714 73597 42372922
Disseminated mucormycosis 89.25 11.57 61 174755 1330 42445189
Myalgia 89.12 11.57 161 174655 95919 42350600
Hypokalaemia 88.56 11.57 98 174718 71623 42374896
Swelling 88.54 11.57 58 174758 54827 42391692
Memory impairment 88.14 11.57 48 174768 50174 42396345
Cryptococcal cutaneous infection 87.51 11.57 31 174785 138 42446381
American trypanosomiasis 87.31 11.57 38 174778 318 42446201
Pneumonia bacterial 86.68 11.57 196 174620 15496 42431023
Venoocclusive disease 86.42 11.57 93 174723 3822 42442697
Neuropathy peripheral 86.37 11.57 180 174636 101673 42344846
Renal tubular acidosis 86.06 11.57 79 174737 2671 42443848
Nightmare 85.64 11.57 4 174812 25008 42421511
Fusarium infection 85.50 11.57 63 174753 1553 42444966
Psoriatic arthropathy 85.46 11.57 4 174812 24963 42421556
Human herpesvirus 6 encephalitis 85.28 11.57 44 174772 557 42445962
Rhinovirus infection 85.02 11.57 119 174697 6429 42440090
Enterococcal bacteraemia 84.22 11.57 77 174739 2590 42443929
Cytomegalovirus enteritis 84.13 11.57 45 174771 616 42445903
Cushingoid 83.95 11.57 86 174730 3336 42443183
Pneumonia pseudomonal 83.65 11.57 102 174714 4807 42441712
Tubulointerstitial nephritis 83.44 11.57 302 174514 31246 42415273
Blood pressure decreased 83.31 11.57 70 174746 58262 42388257
Anogenital warts 82.38 11.57 46 174770 689 42445830
Abdominal distension 82.18 11.57 104 174712 71631 42374888
Hallucination 82.14 11.57 69 174747 57438 42389081
Tachycardia 82.10 11.57 183 174633 100904 42345615
Mediastinitis 82.08 11.57 52 174764 993 42445526
Sepsis 81.98 11.57 1209 173607 198125 42248394
Dermoid cyst 81.88 11.57 30 174786 150 42446369
Transient ischaemic attack 81.70 11.57 19 174797 33720 42412799
Infection in an immunocompromised host 81.53 11.57 52 174764 1005 42445514
Cystitis viral 80.96 11.57 55 174761 1187 42445332
Pyelonephritis acute 80.55 11.57 73 174743 2427 42444092
Central nervous system lymphoma 80.13 11.57 57 174759 1328 42445191
Visceral leishmaniasis 79.77 11.57 53 174763 1101 42445418
Infusion related reaction 79.67 11.57 79 174737 60727 42385792
Enterocolitis viral 79.67 11.57 39 174777 438 42446081
Dry mouth 79.41 11.57 32 174784 39847 42406672
Coronary artery disease 78.53 11.57 63 174753 53657 42392862
Post transplant distal limb syndrome 78.23 11.57 38 174778 419 42446100
Adverse drug reaction 77.94 11.57 28 174788 37406 42409113
Epidermodysplasia verruciformis 77.63 11.57 33 174783 259 42446260
Therapeutic product effect decreased 77.01 11.57 32 174784 39118 42407401
Emphysematous pyelonephritis 76.81 11.57 29 174787 160 42446359
Herpes zoster meningoencephalitis 76.69 11.57 39 174777 478 42446041
Haemoglobin decreased 76.59 11.57 282 174534 132189 42314330
Abdominal discomfort 76.35 11.57 119 174697 75136 42371383
Unevaluable event 76.03 11.57 23 174793 34265 42412254
Dysgeusia 75.69 11.57 23 174793 34166 42412353
Rheumatoid arthritis 75.30 11.57 40 174776 42400 42404119
Microsporidia infection 75.06 11.57 51 174765 1101 42445418
Nodular regenerative hyperplasia 74.55 11.57 49 174767 999 42445520
Chronic graft versus host disease in eye 74.54 11.57 32 174784 258 42446261
Chills 74.19 11.57 173 174643 93893 42352626
Sedation 74.11 11.57 17 174799 30458 42416061
Therapeutic product effect incomplete 74.06 11.57 110 174706 70829 42375690
Cutaneous mucormycosis 74.02 11.57 41 174775 604 42445915
Pneumoperitoneum 73.81 11.57 68 174748 2310 42444209
Wound dehiscence 73.09 11.57 84 174732 3716 42442803
Disseminated mycobacterium avium complex infection 72.66 11.57 30 174786 217 42446302
Parvovirus infection 72.65 11.57 37 174779 455 42446064
Febrile neutropenia 72.52 11.57 455 174361 185248 42261271
Cardiac disorder 72.01 11.57 57 174759 48875 42397644
Complications of transplanted liver 71.90 11.57 32 174784 284 42446235
Chronic graft versus host disease in intestine 71.82 11.57 36 174780 427 42446092
Human herpesvirus 6 infection reactivation 71.53 11.57 36 174780 431 42446088
Contusion 70.99 11.57 42 174774 41943 42404576
Cerebral fungal infection 69.72 11.57 33 174783 342 42446177
Erythema infectiosum 69.54 11.57 26 174790 139 42446380
Corynebacterium infection 69.51 11.57 44 174772 839 42445680
Cutaneous malacoplakia 69.23 11.57 25 174791 119 42446400
Epstein-Barr virus test positive 69.10 11.57 40 174776 644 42445875
Apoptosis 68.89 11.57 38 174778 555 42445964
Adenoviral hepatitis 68.20 11.57 37 174779 522 42445997
Incorrect dose administered 68.05 11.57 70 174746 52904 42393615
Eye infection toxoplasmal 67.61 11.57 31 174785 297 42446222
Skin squamous cell carcinoma metastatic 67.36 11.57 22 174794 72 42446447
Renal vein thrombosis 66.89 11.57 35 174781 457 42446062
Rhabdomyolysis 66.88 11.57 137 174679 77882 42368637
Chronic graft versus host disease oral 66.84 11.57 33 174783 378 42446141
Graft versus host disease in eye 66.80 11.57 31 174785 306 42446213
Skin lesion 66.73 11.57 254 174562 26920 42419599
Inferior vena cava stenosis 66.68 11.57 22 174794 75 42446444
Urinary tract infection bacterial 66.35 11.57 64 174752 2306 42444213
Malignant fibrous histiocytoma 65.89 11.57 29 174787 250 42446269
Cutaneous T-cell lymphoma 65.67 11.57 59 174757 1939 42444580
Central nervous system viral infection 65.47 11.57 25 174791 143 42446376
Nephrolithiasis 64.92 11.57 35 174781 36795 42409724
Respiratory depression 64.65 11.57 3 174813 18865 42427654
Angioedema 64.39 11.57 48 174768 42429 42404090
Rectal haemorrhage 64.35 11.57 65 174751 49541 42396978
Endocarditis 64.26 11.57 118 174698 8034 42438485
Migraine 64.20 11.57 13 174803 25401 42421118
Basal cell carcinoma 63.87 11.57 222 174594 22511 42424008
Gastroenteritis cryptosporidial 63.85 11.57 28 174788 239 42446280
Gastroenteritis sapovirus 62.87 11.57 25 174791 162 42446357
Oropharyngeal squamous cell carcinoma 62.67 11.57 28 174788 251 42446268
Swollen tongue 62.45 11.57 7 174809 21224 42425295
Herpes simplex pneumonia 62.39 11.57 28 174788 254 42446265
Incorrect route of product administration 62.31 11.57 12 174804 24293 42422226
Transitional cell carcinoma 61.96 11.57 65 174751 2593 42443926
New onset diabetes after transplantation 61.95 11.57 26 174790 197 42446322
Acute myocardial infarction 61.88 11.57 89 174727 58076 42388443
Drug withdrawal syndrome 61.19 11.57 8 174808 21541 42424978
Dengue fever 61.14 11.57 32 174784 418 42446101
Injection site erythema 61.10 11.57 6 174810 20189 42426330
Pericarditis fungal 60.63 11.57 26 174790 209 42446310
Rash pruritic 60.61 11.57 31 174785 33572 42412947
Foetal exposure during pregnancy 60.23 11.57 63 174753 47248 42399271
Choriomeningitis lymphocytic 60.17 11.57 23 174793 132 42446387
Herpes virus infection 60.15 11.57 75 174741 3617 42442902
Flushing 59.89 11.57 39 174777 36989 42409530
Immune reconstitution inflammatory syndrome 59.74 11.57 130 174686 10013 42436506
Renal transplant 59.59 11.57 61 174755 2364 42444155
Gastrointestinal mucormycosis 59.47 11.57 30 174786 361 42446158
Growth retardation 59.44 11.57 61 174755 2371 42444148
Subcapsular renal haematoma 59.36 11.57 34 174782 536 42445983
Sleep disorder due to a general medical condition 59.08 11.57 3 174813 17450 42429069
Emphysematous cystitis 59.03 11.57 27 174789 257 42446262
Skin squamous cell carcinoma recurrent 59.01 11.57 21 174795 95 42446424
Short stature 58.96 11.57 31 174785 409 42446110
Disseminated cytomegaloviral infection 58.94 11.57 27 174789 258 42446261
Stevens-Johnson syndrome 58.91 11.57 10 174806 22168 42424351
Lupus nephritis 58.88 11.57 33 174783 498 42446021
Hepatic cancer recurrent 58.67 11.57 28 174788 296 42446223
Solar lentigo 58.59 11.57 35 174781 599 42445920
Tinnitus 57.98 11.57 23 174793 28915 42417604
Glomerulonephritis proliferative 57.54 11.57 26 174790 240 42446279
Full blood count decreased 57.50 11.57 8 174808 20552 42425967
Chromoblastomycosis 57.48 11.57 21 174795 104 42446415
Superinfection bacterial 57.44 11.57 47 174769 1357 42445162
Enteritis 57.41 11.57 133 174683 10683 42435836
Hot flush 57.37 11.57 11 174805 22340 42424179
Atypical haemolytic uraemic syndrome 57.30 11.57 33 174783 526 42445993
Pre-engraftment immune reaction 57.21 11.57 23 174793 154 42446365
Abscess fungal 57.08 11.57 28 174788 316 42446203
Central nervous system infection 56.88 11.57 39 174777 855 42445664
Hepatic artery thrombosis 56.80 11.57 26 174790 248 42446271
Tuberculosis 56.73 11.57 127 174689 9972 42436547
Therapy partial responder 56.67 11.57 196 174620 19825 42426694
Steroid diabetes 56.47 11.57 64 174752 2788 42443731
Fungaemia 56.45 11.57 67 174749 3069 42443450
Glomerulonephritis membranoproliferative 56.23 11.57 32 174784 498 42446021
Post procedural bile leak 56.20 11.57 27 174789 290 42446229
Dysplastic naevus 55.95 11.57 35 174781 653 42445866
Abdominal pain upper 55.91 11.57 164 174652 82445 42364074
Discomfort 55.76 11.57 17 174799 25202 42421317
Musculoskeletal pain 55.46 11.57 34 174782 33306 42413213
Haemodialysis 55.38 11.57 127 174689 10133 42436386
Photodermatosis 55.20 11.57 36 174780 724 42445795
Product quality issue 54.93 11.57 5 174811 17877 42428642
Uveitis 54.92 11.57 119 174697 9139 42437380
Cytomegalovirus nephritis 54.73 11.57 21 174795 122 42446397
Respiratory arrest 54.68 11.57 24 174792 28400 42418119
Fungal endocarditis 54.64 11.57 30 174786 434 42446085
Cytomegalovirus gastritis 54.22 11.57 26 174790 278 42446241
Meningoencephalitis herpetic 54.01 11.57 40 174776 994 42445525
Gastrooesophageal reflux disease 53.96 11.57 63 174753 44960 42401559
Mouth ulceration 53.76 11.57 159 174657 14804 42431715
Kaposi's sarcoma 53.72 11.57 36 174780 759 42445760
Hospitalisation 53.69 11.57 143 174673 74187 42372332
Drug effective for unapproved indication 53.53 11.57 97 174719 6536 42439983
Viral test positive 53.35 11.57 24 174792 219 42446300
Enterococcal sepsis 53.12 11.57 53 174763 1991 42444528
Hyponatraemia 52.90 11.57 225 174591 101237 42345282
Locked-in syndrome 52.63 11.57 28 174788 379 42446140
Colitis 52.43 11.57 349 174467 46223 42400296
Blood potassium decreased 52.39 11.57 10 174806 20374 42426145
Blood creatine phosphokinase increased 52.37 11.57 73 174743 48265 42398254
Enterovirus infection 52.30 11.57 43 174773 1250 42445269
Drug dependence 52.23 11.57 27 174789 29067 42417452
White blood cell count increased 52.01 11.57 65 174751 45022 42401497
Heart rate decreased 51.96 11.57 44 174772 36488 42410031
Cardio-respiratory arrest 51.93 11.57 101 174715 58535 42387984
Nephropathy 51.93 11.57 98 174718 6813 42439706
Pneumomediastinum 51.89 11.57 64 174752 3052 42443467
Tularaemia 51.83 11.57 22 174794 172 42446347
Pneumonia necrotising 51.74 11.57 40 174776 1062 42445457
Large intestinal ulcer 51.74 11.57 57 174759 2406 42444113
Polyomavirus test positive 51.72 11.57 22 174794 173 42446346
Drug level fluctuating 51.60 11.57 33 174783 641 42445878
Erectile dysfunction 51.24 11.57 19 174797 24894 42421625
Squamous cell carcinoma of the oral cavity 51.20 11.57 25 174791 279 42446240
Serotonin syndrome 51.03 11.57 21 174795 25824 42420695
Prostatic abscess 51.02 11.57 34 174782 710 42445809
Herpes zoster oticus 51.02 11.57 24 174792 245 42446274
Medication error 50.85 11.57 37 174779 33117 42413402
Benign prostatic hyperplasia 50.68 11.57 12 174804 21040 42425479
Periostitis 50.68 11.57 26 174790 325 42446194
Pasteurella infection 50.60 11.57 19 174797 103 42446416
Dyspepsia 50.49 11.57 57 174759 41295 42405224
Intentional self-injury 50.26 11.57 3 174813 15199 42431320
Neuroleptic malignant syndrome 50.22 11.57 13 174803 21459 42425060
Atypical mycobacterial pneumonia 50.10 11.57 23 174793 221 42446298
Neuroendocrine carcinoma of the skin 49.94 11.57 37 174779 920 42445599
Central nervous system fungal infection 49.82 11.57 28 174788 425 42446094
Scleroderma 49.75 11.57 48 174768 1730 42444789
Orthostatic hypotension 49.71 11.57 32 174784 30538 42415981
Aspergilloma 49.70 11.57 28 174788 427 42446092
Humoral immune defect 49.39 11.57 26 174790 344 42446175
Oropharyngeal pain 49.33 11.57 61 174755 42449 42404070
Clostridium difficile colitis 49.21 11.57 195 174621 21057 42425462
Nasal congestion 49.19 11.57 30 174786 29471 42417048
Vision blurred 48.86 11.57 91 174725 53608 42392911
Prostatic specific antigen increased 48.74 11.57 6 174810 16919 42429600
Bronchitis 48.47 11.57 74 174742 47127 42399392
Accidental exposure to product 48.36 11.57 12 174804 20381 42426138
Glomerulosclerosis 48.34 11.57 35 174781 839 42445680
Hepatocellular carcinoma 48.24 11.57 105 174711 8089 42438430
Candida sepsis 48.14 11.57 43 174773 1402 42445117
Lung abscess 47.98 11.57 63 174753 3200 42443319
Fungal abscess central nervous system 47.94 11.57 20 174796 149 42446370
Prostate cancer 47.79 11.57 68 174748 44575 42401944
Osteomyelitis fungal 47.67 11.57 25 174791 328 42446191
Dysphonia 47.34 11.57 29 174787 28421 42418098
Guillain-Barre syndrome 47.32 11.57 97 174719 7166 42439353
Varicella 47.25 11.57 50 174766 2015 42444504
Weight increased 47.22 11.57 255 174561 107728 42338791
Graft infection 47.07 11.57 27 174789 427 42446092
Mycobacterium avium complex infection 46.95 11.57 60 174756 2967 42443552
Skin exfoliation 46.79 11.57 61 174755 41492 42405027
Drug eruption 46.79 11.57 18 174798 23057 42423462
Opportunistic infection 46.77 11.57 49 174767 1952 42444567
Arthropathy 46.75 11.57 32 174784 29565 42416954
Urinary tract infection enterococcal 46.67 11.57 37 174779 1020 42445499
Bordetella infection 46.62 11.57 20 174796 161 42446358
Herpes zoster 46.61 11.57 296 174520 38581 42407938
Multiple sclerosis relapse 46.60 11.57 3 174813 14261 42432258
Hypothyroidism 46.42 11.57 38 174778 32046 42414473
Seizure 46.19 11.57 297 174519 120264 42326255
Cutaneous blastomycosis 46.19 11.57 14 174802 33 42446486
Presyncope 46.17 11.57 17 174799 22370 42424149
Cytomegalovirus gastroenteritis 46.16 11.57 24 174792 309 42446210
Biliary anastomosis complication 46.08 11.57 17 174799 87 42446432
Disseminated strongyloidiasis 45.88 11.57 28 174788 499 42446020
Klebsiella sepsis 45.82 11.57 56 174760 2645 42443874
H1N1 influenza 45.60 11.57 38 174778 1126 42445393
Orchitis 45.40 11.57 51 174765 2200 42444319
Head injury 45.28 11.57 14 174802 20568 42425951
Heart rate increased 45.22 11.57 94 174722 53161 42393358
Cough 45 11.57 490 174326 177613 42268906
Retinitis 45 11.57 27 174789 466 42446053
Feeling hot 44.89 11.57 20 174796 23462 42423057
Oliguria 44.56 11.57 110 174706 9203 42437316
Glomerulonephropathy 44.34 11.57 21 174795 218 42446301
Injection site swelling 44.32 11.57 8 174808 16965 42429554
Flatulence 44.18 11.57 24 174792 25128 42421391
Inflammatory bowel disease 44.14 11.57 63 174753 3466 42443053
Microangiopathic haemolytic anaemia 44.02 11.57 37 174779 1110 42445409
Oesophageal ulcer 43.95 11.57 65 174751 3694 42442825
Adverse event 43.85 11.57 21 174795 23619 42422900
Ileal ulcer 43.74 11.57 34 174782 910 42445609
Respiratory tract infection fungal 43.49 11.57 32 174784 787 42445732
Dyskinesia 43.49 11.57 25 174791 25365 42421154
Escherichia urinary tract infection 43.38 11.57 70 174746 4293 42442226
Granuloma 43.17 11.57 67 174749 3974 42442545
Endocarditis bacterial 43.17 11.57 38 174778 1215 42445304
Rhinorrhoea 43.16 11.57 40 174776 31754 42414765
Contraindicated product administered 43.12 11.57 25 174791 25247 42421272
Muir-Torre syndrome 43.08 11.57 12 174804 18 42446501
Pneumonia viral 43.08 11.57 69 174747 4205 42442314
Obstructive airways disorder 42.95 11.57 24 174792 24735 42421784
Meningoencephalitis viral 42.95 11.57 19 174797 166 42446353
Necrotising oesophagitis 42.90 11.57 34 174782 937 42445582
Joint injury 42.76 11.57 5 174811 14671 42431848
Cytokine release syndrome 42.73 11.57 73 174743 44454 42402065
Acute disseminated encephalomyelitis 42.37 11.57 18 174798 141 42446378
External auditory canal atresia 42.37 11.57 19 174797 172 42446347
Irritability 42.35 11.57 32 174784 28096 42418423
Adenovirus reactivation 42.32 11.57 24 174792 371 42446148
Hepatitis B reactivation 42.22 11.57 71 174745 4507 42442012
Metastatic squamous cell carcinoma 42.20 11.57 29 174787 638 42445881
Cardiac infection 42.05 11.57 21 174795 247 42446272
Encapsulating peritoneal sclerosis 42.04 11.57 28 174788 584 42445935
Liver abscess 41.80 11.57 74 174742 4896 42441623
Cutaneous tuberculosis 41.77 11.57 17 174799 118 42446401
Bile duct stenosis 41.75 11.57 39 174777 1349 42445170
Staphylococcal bacteraemia 41.70 11.57 120 174696 11001 42435518
Engraftment syndrome 41.70 11.57 39 174777 1351 42445168
Neck pain 41.65 11.57 37 174779 29977 42416542
Peritonitis 41.57 11.57 169 174647 18464 42428055
Intestinal tuberculosis 41.42 11.57 18 174798 150 42446369
Complications of transplant surgery 41.34 11.57 26 174790 490 42446029
Oxygen saturation decreased 41.22 11.57 132 174684 64555 42381964
Pancreatitis necrotising 41.09 11.57 62 174754 3587 42442932
Microtia 41.04 11.57 21 174795 261 42446258
Heart rate irregular 40.98 11.57 8 174808 16042 42430477
Lactic acidosis 40.92 11.57 77 174739 45184 42401335
Extrapulmonary tuberculosis 40.91 11.57 18 174798 155 42446364
Meningitis fungal 40.56 11.57 19 174797 192 42446327
Osteoarthritis 40.43 11.57 25 174791 24380 42422139
Adenoviral haemorrhagic cystitis 40.12 11.57 26 174790 517 42446002
Diarrhoea haemorrhagic 40.06 11.57 94 174722 7613 42438906
Renal cell carcinoma 39.93 11.57 77 174739 5440 42441079
Infectious pleural effusion 39.91 11.57 57 174759 3138 42443381
Disseminated aspergillosis 39.78 11.57 42 174774 1688 42444831
Osteoporosis 39.67 11.57 143 174673 14763 42431756
Chronic inflammatory demyelinating polyradiculoneuropathy 39.57 11.57 36 174780 1203 42445316
Encephalitis cytomegalovirus 39.57 11.57 36 174780 1203 42445316
Disseminated varicella zoster vaccine virus infection 39.40 11.57 14 174802 63 42446456
Ureteral necrosis 39.25 11.57 13 174803 45 42446474
Accidental overdose 39.22 11.57 35 174781 28295 42418224
Urinoma 39.12 11.57 20 174796 248 42446271
Respiratory syncytial virus infection 39.12 11.57 89 174727 7063 42439456
Cerebral aspergillosis 38.85 11.57 42 174774 1735 42444784
Epstein-Barr virus antibody positive 38.85 11.57 21 174795 294 42446225
Tracheitis 38.81 11.57 33 174783 1006 42445513
Diabetes mellitus 38.79 11.57 397 174419 59690 42386829
Appendicitis 38.71 11.57 18 174798 20595 42425924
Pneumocephalus 38.67 11.57 18 174798 179 42446340
Dysphagia 38.67 11.57 160 174656 72559 42373960
Mobility decreased 38.56 11.57 53 174763 35253 42411266
Engraft failure 38.44 11.57 26 174790 557 42445962
Bacterial infection 38.34 11.57 220 174596 27659 42418860
Skin mass 38.32 11.57 70 174746 4746 42441773
Muscular weakness 38.28 11.57 194 174622 83304 42363215
Skin graft rejection 38.28 11.57 12 174804 33 42446486
Miosis 38.15 11.57 5 174811 13441 42433078
Lactobacillus infection 38.13 11.57 22 174794 352 42446167
Burkholderia cepacia complex infection 37.99 11.57 21 174795 308 42446211
Paranoia 37.97 11.57 6 174810 14020 42432499
Odynophagia 37.87 11.57 85 174731 6685 42439834
Mesangioproliferative glomerulonephritis 37.71 11.57 17 174799 156 42446363
Coccidioidomycosis 37.69 11.57 30 174786 832 42445687
B-lymphocyte count decreased 37.47 11.57 30 174786 839 42445680
Eczema 37.40 11.57 51 174765 34035 42412484
Haemodynamic instability 37.35 11.57 125 174691 12432 42434087
Acute myeloid leukaemia recurrent 37.20 11.57 58 174758 3454 42443065
Delirium 37.20 11.57 102 174714 52417 42394102
Restlessness 37.16 11.57 39 174777 29210 42417309
Pyogenic granuloma 36.87 11.57 20 174796 282 42446237
Peritonitis pneumococcal 36.87 11.57 11 174805 24 42446495
Troponin increased 36.81 11.57 16 174800 19046 42427473
Anaphylactic reaction 36.66 11.57 75 174741 42668 42403851
Urinary tract infection viral 36.57 11.57 12 174804 40 42446479
Lung transplant 36.54 11.57 47 174769 2339 42444180
Anaphylactic shock 36.39 11.57 26 174790 23491 42423028
Ventricular tachycardia 36.35 11.57 42 174774 30118 42416401
Postoperative wound infection 36.34 11.57 75 174741 5567 42440952
Tuberculosis of central nervous system 36.32 11.57 18 174798 208 42446311
Abdominal pain 36.28 11.57 556 174260 189915 42256604
Infective aneurysm 36.25 11.57 32 174784 1027 42445492
Vertigo 36.09 11.57 53 174763 34294 42412225
Renal and pancreas transplant rejection 35.98 11.57 11 174805 27 42446492
Upper gastrointestinal haemorrhage 35.66 11.57 43 174773 30256 42416263
Eye pruritus 35.57 11.57 3 174813 11409 42435110
Sporotrichosis 35.32 11.57 13 174803 66 42446453
Klebsiella bacteraemia 35.32 11.57 46 174770 2318 42444201
Bone marrow transplant rejection 35.30 11.57 18 174798 222 42446297
Pulmonary tuberculosis 35.28 11.57 73 174743 5428 42441091
Meningitis viral 35.08 11.57 32 174784 1073 42445446
Serratia infection 35.02 11.57 34 174782 1235 42445284
Bacterial pyelonephritis 34.82 11.57 20 174796 317 42446202
Sleep apnoea syndrome 34.61 11.57 23 174793 21585 42424934
Scrotal ulcer 34.61 11.57 23 174793 478 42446041
Gastroenteritis astroviral 34.54 11.57 13 174803 71 42446448
Renal artery stenosis 34.48 11.57 45 174771 2272 42444247
Pneumonia influenzal 34.37 11.57 41 174775 1888 42444631
Lymphadenitis bacterial 34.32 11.57 12 174804 51 42446468
Sinusitis aspergillus 34.30 11.57 14 174802 98 42446421
Impaired quality of life 34.29 11.57 8 174808 14169 42432350
Escherichia sepsis 34.24 11.57 74 174742 5673 42440846
Hyperphosphataemia 34.23 11.57 6 174810 12998 42433521
Proteus infection 34.22 11.57 35 174781 1355 42445164
Myopathy 34.09 11.57 129 174687 13632 42432887
Hyperplasia 33.80 11.57 26 174790 685 42445834
Lip swelling 33.73 11.57 18 174798 19035 42427484
Swelling face 33.61 11.57 38 174778 27516 42419003
Bronchiolitis obliterans syndrome 33.60 11.57 19 174797 292 42446227
Renal haematoma 33.49 11.57 25 174791 629 42445890
Unresponsive to stimuli 33.44 11.57 48 174768 31355 42415164
Bone pain 33.41 11.57 29 174787 23763 42422756
Pollakiuria 33.38 11.57 26 174790 22479 42424040
Haematemesis 33.32 11.57 45 174771 30154 42416365
Cytomegalovirus hepatitis 33.31 11.57 23 174793 510 42446009
Hypocalcaemia 33.25 11.57 45 174771 30128 42416391
Mucosal inflammation 33.21 11.57 329 174487 49045 42397474
Wound infection 33.20 11.57 92 174724 8254 42438265
Urinary retention 32.97 11.57 78 174738 42136 42404383
Infertility 32.96 11.57 17 174799 215 42446304
Extrapyramidal disorder 32.95 11.57 13 174803 16399 42430120
Pallor 32.94 11.57 42 174774 28844 42417675
Aphthous ulcer 32.91 11.57 74 174742 5827 42440692
Frequent bowel movements 32.69 11.57 24 174792 21383 42425136
Cold sweat 32.67 11.57 4 174812 11326 42435193
Orf 32.58 11.57 10 174806 25 42446494
Immunosuppression 32.46 11.57 92 174724 8361 42438158
Cardiac failure 32.45 11.57 281 174535 106575 42339944
Dysarthria 32.35 11.57 72 174744 39735 42406784
Empyema 32.31 11.57 60 174756 4120 42442399
Heartland virus infection 32.30 11.57 10 174806 26 42446493
Infection 32.25 11.57 642 174174 111426 42335093
Paternal exposure before pregnancy 32.18 11.57 11 174805 43 42446476
Feeling cold 32.02 11.57 7 174809 12966 42433553
Graft thrombosis 31.98 11.57 18 174798 274 42446245
Chromophobe renal cell carcinoma 31.97 11.57 12 174804 65 42446454
Complications of bone marrow transplant 31.96 11.57 17 174799 230 42446289
Gastrointestinal disorder 31.93 11.57 312 174504 46341 42400178
Depressed level of consciousness 31.89 11.57 96 174720 47874 42398645
Lethargy 31.78 11.57 93 174723 46797 42399722
Removal of renal transplant 31.77 11.57 10 174806 28 42446491
Skin necrosis 31.73 11.57 76 174740 6238 42440281
Epstein Barr virus positive mucocutaneous ulcer 31.67 11.57 23 174793 554 42445965
Metastatic carcinoma of the bladder 31.64 11.57 17 174799 235 42446284
Propionibacterium infection 31.64 11.57 17 174799 235 42446284
Disseminated Bacillus Calmette-Guerin infection 31.58 11.57 18 174798 281 42446238
Seroconversion test negative 31.55 11.57 8 174808 6 42446513
Zoonotic bacterial infection 31.52 11.57 12 174804 68 42446451
Burning sensation 31.52 11.57 24 174792 20989 42425530
Aspiration 31.51 11.57 17 174799 17869 42428650
Disturbance in attention 31.46 11.57 46 174770 29820 42416699
Tumour lysis syndrome 31.34 11.57 27 174789 22204 42424315
Transitional cell carcinoma metastatic 31.26 11.57 13 174803 96 42446423
Donor specific antibody present 31.23 11.57 15 174801 161 42446358
Skin infection 31.18 11.57 97 174719 9283 42437236
Ventricular fibrillation 31.14 11.57 47 174769 30076 42416443
Aspartate aminotransferase increased 31.14 11.57 187 174629 76976 42369543
Necrotising retinitis 31.09 11.57 29 174787 1001 42445518
Laboratory test abnormal 31.08 11.57 29 174787 22949 42423570
Cutaneous nocardiosis 31.05 11.57 16 174800 202 42446317
Road traffic accident 31.02 11.57 20 174796 19073 42427446
Taste disorder 30.96 11.57 3 174813 10204 42436315
Herpes simplex oesophagitis 30.90 11.57 17 174799 247 42446272
Muscle rigidity 30.81 11.57 6 174810 12053 42434466
Product prescribing error 30.79 11.57 37 174779 26075 42420444
Underdose 30.62 11.57 15 174801 16651 42429868
Paradoxical drug reaction 30.54 11.57 63 174753 4675 42441844
Blood phosphorus increased 30.43 11.57 7 174809 12518 42434001
Chronic hepatitis 30.34 11.57 25 174791 729 42445790
Renal adenoma 30.33 11.57 10 174806 34 42446485
Peripheral artery aneurysm 30.33 11.57 22 174794 529 42445990
Morganella infection 30.23 11.57 23 174793 596 42445923
Renal tubular disorder 30.15 11.57 64 174752 4845 42441674
Skin laceration 30.15 11.57 10 174806 14048 42432471
Cognitive disorder 30.13 11.57 59 174757 34113 42412406
Erythema multiforme 30.09 11.57 3 174813 9974 42436545
Osteomyelitis bacterial 30.07 11.57 19 174797 361 42446158
Diabetic cardiomyopathy 30.06 11.57 9 174807 20 42446499
Apoptotic colonopathy 30.05 11.57 13 174803 107 42446412
Plasmodium falciparum infection 30.02 11.57 12 174804 79 42446440
Pharyngeal polyp 30.01 11.57 8 174808 9 42446510
Depressed mood 29.91 11.57 31 174785 23353 42423166
Infectious crystalline keratopathy 29.86 11.57 11 174805 56 42446463
Acinetobacter sepsis 29.85 11.57 13 174803 109 42446410
Blood test abnormal 29.82 11.57 8 174808 12898 42433621
Central nervous system vasculitis 29.74 11.57 23 174793 611 42445908
Metastases to skin 29.73 11.57 22 174794 546 42445973
Angina pectoris 29.70 11.57 56 174760 32840 42413679
Activated partial thromboplastin time prolonged 29.69 11.57 14 174802 15889 42430630
Metastases to salivary gland 29.64 11.57 12 174804 82 42446437
Product storage error 29.63 11.57 5 174811 11135 42435384
Fungal sepsis 29.61 11.57 29 174787 1065 42445454
Abnormal behaviour 29.60 11.57 39 174777 26412 42420107
Haematochezia 29.58 11.57 131 174685 58305 42388214
Arthritis 29.56 11.57 82 174734 41983 42404536
Neuralgia 29.55 11.57 37 174779 25610 42420909
Dystonia 29.42 11.57 8 174808 12782 42433737
Haemosiderosis 29.39 11.57 18 174798 323 42446196
Blood cholesterol increased 29.35 11.57 40 174776 26701 42419818
Alanine aminotransferase increased 29.34 11.57 227 174589 88179 42358340
Limb injury 29.27 11.57 11 174805 14294 42432225
Lymphocytic infiltration 29.26 11.57 27 174789 919 42445600
Disseminated intravascular coagulation 29.24 11.57 188 174628 24606 42421913
Withdrawal syndrome 29.18 11.57 12 174804 14763 42431756
Splenic abscess 28.98 11.57 23 174793 635 42445884
Systemic candida 28.88 11.57 66 174750 5253 42441266
Legionella infection 28.82 11.57 22 174794 573 42445946
Emphysematous cholecystitis 28.81 11.57 12 174804 89 42446430
Dyspnoea exertional 28.79 11.57 107 174709 50041 42396478
Pleocytosis 28.77 11.57 23 174793 642 42445877
Cystitis escherichia 28.72 11.57 15 174801 195 42446324
Illness 28.68 11.57 36 174780 24894 42421625
Biphasic mesothelioma 28.65 11.57 11 174805 64 42446455
Coronavirus infection 28.65 11.57 65 174751 5149 42441370
Herpes simplex hepatitis 28.62 11.57 14 174802 157 42446362
Disseminated trichosporonosis 28.58 11.57 12 174804 91 42446428
Arteriosclerosis coronary artery 28.44 11.57 21 174795 18656 42427863
Arteritis infective 28.37 11.57 11 174805 66 42446453
Parametritis 28.34 11.57 8 174808 13 42446506
Plasma cell myeloma 28.31 11.57 100 174716 47478 42399041
Varicella zoster pneumonia 28.29 11.57 16 174800 246 42446273
Pain in jaw 28.28 11.57 12 174804 14490 42432029
Hepatic fibrosis 28.19 11.57 62 174754 4810 42441709
Musculoskeletal discomfort 28.19 11.57 3 174813 9473 42437046
Myocarditis mycotic 28.14 11.57 10 174806 45 42446474
Cutaneous sporotrichosis 28.14 11.57 10 174806 45 42446474
Superinfection viral 28.14 11.57 9 174807 27 42446492
Retinopathy haemorrhagic 28.10 11.57 11 174805 68 42446451
Pericarditis constrictive 28.07 11.57 21 174795 530 42445989
Myelitis transverse 27.99 11.57 31 174785 1316 42445203
Cryptococcal fungaemia 27.86 11.57 14 174802 167 42446352
Blood pressure fluctuation 27.80 11.57 42 174774 26866 42419653
Papilloma 27.77 11.57 18 174798 358 42446161
Pleural adhesion 27.75 11.57 15 174801 210 42446309
Arthritis bacterial 27.75 11.57 69 174747 5799 42440720
Drug level decreased 27.65 11.57 97 174719 9880 42436639
Melaena 27.62 11.57 75 174741 38671 42407848
Gastrointestinal fungal infection 27.46 11.57 16 174800 261 42446258
Product administration error 27.45 11.57 21 174795 18322 42428197
Urinary incontinence 27.41 11.57 29 174787 21639 42424880
Metastases to lung 27.40 11.57 106 174710 11318 42435201
Sphincter of Oddi dysfunction 27.26 11.57 15 174801 218 42446301
Trichosporon infection 27.20 11.57 26 174790 926 42445593
Ageusia 27.19 11.57 7 174809 11598 42434921
Pulmonary air leakage 27.14 11.57 15 174801 220 42446299
Synovitis 27.13 11.57 15 174801 15552 42430967
Neutrophil morphology abnormal 27.07 11.57 11 174805 76 42446443
Subdural haematoma 27.05 11.57 33 174783 23105 42423414
Acute hepatic failure 27.03 11.57 140 174676 16933 42429586
Renal cyst infection 27.01 11.57 12 174804 106 42446413
Bacterial translocation 27.01 11.57 22 174794 631 42445888
Serpiginous choroiditis 27.00 11.57 6 174810 0 42446519
Phaeohyphomycotic brain abscess 26.97 11.57 10 174806 52 42446467
Anuria 26.85 11.57 106 174710 11426 42435093
Joint tuberculosis 26.82 11.57 10 174806 53 42446466
Neutrophil count increased 26.78 11.57 25 174791 19779 42426740
Myocarditis infectious 26.66 11.57 10 174806 54 42446465
Reversible cerebral vasoconstriction syndrome 26.62 11.57 23 174793 717 42445802
Skin fissures 26.51 11.57 4 174812 9672 42436847
Spindle cell sarcoma 26.48 11.57 13 174803 147 42446372
Serratia sepsis 26.48 11.57 13 174803 147 42446372
Toxic epidermal necrolysis 26.45 11.57 43 174773 26707 42419812
Bone tuberculosis 26.44 11.57 19 174797 450 42446069
Citrobacter infection 26.37 11.57 22 174794 653 42445866
Influenza like illness 26.36 11.57 57 174759 31783 42414736
Scopulariopsis infection 26.32 11.57 13 174803 149 42446370
Intestinal ulcer 26.30 11.57 27 174789 1050 42445469
Vascular pseudoaneurysm 26.27 11.57 43 174773 2669 42443850
Chronic myeloid leukaemia 26.18 11.57 41 174775 2451 42444068
Eosinophil count increased 26.18 11.57 6 174810 10757 42435762
Malignant neoplasm of conjunctiva 26.17 11.57 9 174807 36 42446483
Splenic infection viral 26.17 11.57 9 174807 36 42446483
Mycobacterium fortuitum infection 26.08 11.57 18 174798 399 42446120
Glomerulonephritis rapidly progressive 26.05 11.57 25 174791 895 42445624
Amnesia 26.03 11.57 48 174768 28389 42418130
Staphylococcal scalded skin syndrome 26.02 11.57 17 174799 343 42446176
Normocytic anaemia 25.98 11.57 50 174766 3527 42442992
Glomerulonephritis membranous 25.96 11.57 31 174785 1429 42445090
Transplantation associated food allergy 25.93 11.57 10 174806 59 42446460
Red blood cell count decreased 25.91 11.57 60 174756 32655 42413864
Lacrimation increased 25.86 11.57 8 174808 11750 42434769
Osteonecrosis of jaw 25.81 11.57 24 174792 19025 42427494
Acid fast bacilli infection 25.81 11.57 12 174804 119 42446400
Hepatic cytolysis 25.76 11.57 44 174772 26800 42419719
Sinus tachycardia 25.72 11.57 28 174788 20625 42425894
Cytomegalovirus enterocolitis 25.64 11.57 30 174786 1353 42445166
Ophthalmic herpes zoster 25.62 11.57 27 174789 1083 42445436
Pyelonephritis chronic 25.60 11.57 9 174807 39 42446480
Hypersomnia 25.60 11.57 14 174802 14604 42431915
Passenger lymphocyte syndrome 25.59 11.57 11 174805 89 42446430
Ocular hyperaemia 25.56 11.57 17 174799 15946 42430573
Biopsy kidney abnormal 25.55 11.57 12 174804 122 42446397
Cholelithiasis 25.54 11.57 35 174781 23311 42423208
Eosinophilia 25.52 11.57 61 174755 32838 42413681
CEC syndrome 25.52 11.57 8 174808 22 42446497
Cyanosis 25.46 11.57 15 174801 15016 42431503
Stomatitis 25.36 11.57 113 174703 50216 42396303
Bladder transitional cell carcinoma 25.34 11.57 42 174774 2634 42443885
Skin discolouration 25.28 11.57 29 174787 20861 42425658
Central nervous system immune reconstitution inflammatory response 25.26 11.57 8 174808 23 42446496
Histoplasmosis cutaneous 25.24 11.57 9 174807 41 42446478
Gait inability 25.21 11.57 34 174782 22799 42423720
Autoimmune haemolytic anaemia 25.06 11.57 65 174751 5606 42440913
Reticulocytopenia 25.03 11.57 13 174803 167 42446352
Eosinophilic granulomatosis with polyangiitis 25.03 11.57 3 174813 8635 42437884
Gastrointestinal haemorrhage 25.00 11.57 268 174548 97458 42349061
Meningeal neoplasm 24.97 11.57 11 174805 95 42446424
Extranodal marginal zone B-cell lymphoma (MALT type) 24.96 11.57 16 174800 312 42446207
Haemoptysis 24.90 11.57 101 174715 46066 42400453
Faeces discoloured 24.80 11.57 20 174796 16994 42429525
Endothelial dysfunction 24.78 11.57 11 174805 97 42446422
Ureteric anastomosis complication 24.73 11.57 9 174807 44 42446475
Plasmacytoma 24.64 11.57 55 174761 4309 42442210
Bronchospasm 24.59 11.57 11 174805 12874 42433645
B-cell lymphoma 24.54 11.57 59 174757 4854 42441665
Lepromatous leprosy 24.50 11.57 10 174806 70 42446449
Hirsutism 24.50 11.57 15 174801 269 42446250
Lymph node tuberculosis 24.46 11.57 19 174797 508 42446011
Glucose tolerance impaired 24.45 11.57 53 174763 4071 42442448
Acarodermatitis 24.28 11.57 22 174794 731 42445788
Hypertrophic cardiomyopathy 24.25 11.57 30 174786 1435 42445084
Perinephric collection 24.24 11.57 13 174803 179 42446340
Enterocolitis haemorrhagic 24.23 11.57 26 174790 1065 42445454
Non-cirrhotic portal hypertension 24.20 11.57 17 174799 388 42446131
Acute kidney injury 24.14 11.57 1783 173033 365554 42080965
Large intestine perforation 24.12 11.57 90 174726 9446 42437073
Cardiac arrest 24.03 11.57 310 174506 109010 42337509
Central nervous system lesion 23.99 11.57 79 174737 7791 42438728
Gastritis fungal 23.96 11.57 12 174804 142 42446377
Gingivitis ulcerative 23.94 11.57 14 174802 230 42446289
Obstructive nephropathy 23.94 11.57 9 174807 49 42446470
Trichophytic granuloma 23.94 11.57 9 174807 49 42446470
Serum sickness 23.92 11.57 37 174779 2188 42444331
Lung adenocarcinoma stage IV 23.89 11.57 12 174804 143 42446376
Pneumonia acinetobacter 23.88 11.57 14 174802 231 42446288
Microsporum infection 23.87 11.57 8 174808 29 42446490
Injury 23.87 11.57 34 174782 22282 42424237
Arrhythmia 23.82 11.57 85 174731 40232 42406287
Wound infection pseudomonas 23.81 11.57 16 174800 339 42446180
Escherichia bacteraemia 23.77 11.57 60 174756 5089 42441430
Pulmonary cavitation 23.70 11.57 28 174788 1276 42445243
Lymphocyte count decreased 23.67 11.57 49 174767 27760 42418759
Chronic kidney disease 23.64 11.57 297 174519 46944 42399575
Impaired work ability 23.58 11.57 10 174806 12081 42434438
Body temperature decreased 23.55 11.57 15 174801 14398 42432121
Poor quality sleep 23.49 11.57 5 174811 9435 42437084
Anger 23.49 11.57 12 174804 13006 42433513
Toxic optic neuropathy 23.47 11.57 25 174791 1015 42445504
Renal arteriosclerosis 23.47 11.57 15 174801 291 42446228
Lymphangiectasia 23.46 11.57 8 174808 31 42446488
Oesophageal stenosis 23.38 11.57 35 174781 2011 42444508
Influenza 23.37 11.57 154 174662 62021 42384498
Rash macular 23.22 11.57 21 174795 16870 42429649
Hypercalcaemia 23.21 11.57 140 174676 17918 42428601
Intracranial pressure increased 23.20 11.57 56 174760 4618 42441901
Haemoperitoneum 23.12 11.57 35 174781 2031 42444488
Neoplasm progression 23.12 11.57 53 174763 28947 42417572
T-cell lymphoma 23.04 11.57 26 174790 1127 42445392
Lung infiltration 23.04 11.57 116 174700 13873 42432646
Therapy cessation 23.04 11.57 30 174786 20420 42426099
T-cell type acute leukaemia 23.03 11.57 13 174803 199 42446320
Biliary tract disorder 23.03 11.57 26 174790 1128 42445391
Urine output decreased 22.98 11.57 97 174719 10776 42435743
Idiopathic interstitial pneumonia 22.97 11.57 17 174799 422 42446097
Blood glucose decreased 22.96 11.57 15 174801 14204 42432315
Micturition urgency 22.95 11.57 10 174806 11888 42434631
Chronic papillomatous dermatitis 22.94 11.57 9 174807 56 42446463
Transplantation complication 22.82 11.57 14 174802 252 42446267
Fluoride increased 22.81 11.57 9 174807 57 42446462
Intraocular pressure increased 22.77 11.57 68 174748 6365 42440154
Respiratory tract inflammation 22.76 11.57 17 174799 428 42446091
Anal ulcer 22.72 11.57 26 174790 1145 42445374
Fluid retention 22.69 11.57 61 174755 31558 42414961
Epiploic appendagitis 22.68 11.57 9 174807 58 42446461
Iris coloboma 22.67 11.57 7 174809 18 42446501
Cutaneous leishmaniasis 22.63 11.57 14 174802 256 42446263
Acute generalised exanthematous pustulosis 22.55 11.57 4 174812 8591 42437928
Oesophageal carcinoma 22.42 11.57 6 174810 9690 42436829
Large intestine infection 22.42 11.57 35 174781 2086 42444433
Norovirus test positive 22.42 11.57 9 174807 60 42446459
Cholangitis sclerosing 22.40 11.57 33 174783 1869 42444650
Pathergy reaction 22.39 11.57 6 174810 7 42446512
Renal vessel disorder 22.37 11.57 13 174803 211 42446308
Acute allograft nephropathy 22.34 11.57 8 174808 37 42446482
Lip ulceration 22.31 11.57 24 174792 986 42445533
Gastrointestinal toxicity 22.30 11.57 50 174766 3929 42442590
Urosepsis 22.30 11.57 121 174695 14899 42431620
Osmotic demyelination syndrome 22.27 11.57 24 174792 988 42445531
Hallucination, auditory 22.26 11.57 17 174799 14847 42431672
Ureteric dilatation 22.26 11.57 13 174803 213 42446306
Hepatitis infectious mononucleosis 22.25 11.57 10 174806 91 42446428
Hospice care 22.25 11.57 4 174812 8509 42438010
Sinus bradycardia 22.23 11.57 17 174799 14836 42431683
Blood sodium decreased 22.21 11.57 25 174791 18137 42428382
Hyperparathyroidism 22.15 11.57 27 174789 1272 42445247
Infection protozoal 22.14 11.57 7 174809 20 42446499
Viral sepsis 22.13 11.57 11 174805 128 42446391
Nocturia 22.10 11.57 11 174805 12101 42434418
Necrotising fasciitis 22.07 11.57 54 174762 4492 42442027
Pneumonia aspiration 22.02 11.57 118 174698 49960 42396559
Middle insomnia 22.02 11.57 3 174813 7830 42438689
Acute respiratory failure 21.95 11.57 250 174566 38608 42407911
Spinal instability 21.94 11.57 19 174797 594 42445925
Schistosomiasis 21.83 11.57 8 174808 40 42446479
Speech disorder 21.80 11.57 55 174761 29066 42417453
Urinary tract infection pseudomonal 21.78 11.57 27 174789 1294 42445225
Giant cell myocarditis 21.64 11.57 7 174809 22 42446497
Device related infection 21.64 11.57 150 174666 20129 42426390
Oesophageal infection 21.60 11.57 15 174801 336 42446183
Pericarditis infective 21.58 11.57 9 174807 67 42446452
Asphyxia 21.58 11.57 4 174812 8322 42438197
Pneumonia respiratory syncytial viral 21.57 11.57 28 174788 1406 42445113
Diffuse large B-cell lymphoma stage IV 21.55 11.57 18 174798 535 42445984
Weight decreased 21.53 11.57 669 174147 207279 42239240
Clostridium difficile infection 21.53 11.57 163 174653 22496 42424023
Fear 21.50 11.57 9 174807 10956 42435563
Post procedural urine leak 21.41 11.57 11 174805 138 42446381
Herpes simplex test positive 21.39 11.57 13 174803 230 42446289
Osteomyelitis chronic 21.37 11.57 15 174801 342 42446177
Necrotising herpetic retinopathy 21.36 11.57 8 174808 43 42446476
Optic atrophy 21.36 11.57 26 174790 1223 42445296
Deep vein thrombosis 21.35 11.57 207 174609 76750 42369769
Metastases to peritoneum 21.29 11.57 37 174779 2412 42444107
Uraemic encephalopathy 21.25 11.57 16 174800 408 42446111
Tremor 21.25 11.57 275 174541 96654 42349865
Bladder transitional cell carcinoma stage III 21.21 11.57 8 174808 44 42446475
Nephrocalcinosis 21.20 11.57 21 174795 782 42445737
Blindness cortical 21.19 11.57 17 174799 477 42446042
C-reactive protein increased 21.18 11.57 163 174653 63397 42383122
Injection site reaction 21.07 11.57 20 174796 15701 42430818
IIIrd nerve paralysis 21.05 11.57 18 174798 553 42445966
Pulmonary oedema 21.02 11.57 130 174686 53142 42393377
Femur fracture 21.01 11.57 7 174809 9805 42436714
Osteopenia 20.94 11.57 65 174751 6213 42440306
Anaemia 20.92 11.57 938 173878 279340 42167179
Mycobacterium kansasii infection 20.88 11.57 15 174801 355 42446164
Back disorder 20.83 11.57 3 174813 7511 42439008
Nephrectomy 20.82 11.57 22 174794 885 42445634
Disseminated varicella 20.80 11.57 6 174810 11 42446508
Skin burning sensation 20.73 11.57 3 174813 7484 42439035
Throat irritation 20.71 11.57 14 174802 13022 42433497
Hyperfibrinogenaemia 20.69 11.57 10 174806 109 42446410
Hepatotoxicity 20.62 11.57 175 174641 24992 42421527
Seasonal allergy 20.60 11.57 4 174812 8051 42438468
Breath sounds abnormal 20.58 11.57 12 174804 12081 42434438
Salmonellosis 20.56 11.57 26 174790 1272 42445247
Acute graft versus host disease oral 20.55 11.57 7 174809 27 42446492
Hypoacusis 20.50 11.57 28 174788 18674 42427845
Mucosal hypertrophy 20.50 11.57 8 174808 49 42446470
Extra-axial haemorrhage 20.46 11.57 6 174810 12 42446507
Post infection glomerulonephritis 20.45 11.57 10 174806 112 42446407
Hypophosphataemia 20.40 11.57 34 174782 20911 42425608
Respiratory symptom 20.39 11.57 10 174806 11096 42435423
Prescribed overdose 20.38 11.57 14 174802 12913 42433606
Acanthamoeba infection 20.34 11.57 17 174799 506 42446013
Hepatic infection fungal 20.30 11.57 13 174803 253 42446266
Shock haemorrhagic 20.30 11.57 125 174691 16117 42430402
Skin bacterial infection 20.26 11.57 13 174803 254 42446265
Iron deficiency 20.25 11.57 10 174806 11051 42435468
Staphylococcal mediastinitis 20.23 11.57 8 174808 51 42446468
Isosporiasis 20.22 11.57 10 174806 115 42446404
Gastroenteritis adenovirus 20.21 11.57 12 174804 203 42446316
Hepatosplenomegaly 20.17 11.57 53 174763 4607 42441912
Polymorphonuclear chromatin clumping 20.17 11.57 5 174811 3 42446516
Hantaviral infection 20.14 11.57 6 174810 13 42446506
Eye swelling 20.04 11.57 12 174804 11908 42434611
Gastric haemorrhage 20.03 11.57 9 174807 10506 42436013
Herpes zoster cutaneous disseminated 20.01 11.57 12 174804 207 42446312
Therapy interrupted 19.98 11.57 38 174778 22212 42424307
Acanthoma 19.97 11.57 7 174809 30 42446489
Keratouveitis 19.97 11.57 7 174809 30 42446489
Intentional dose omission 19.97 11.57 6 174810 8980 42437539
Disseminated toxoplasmosis 19.91 11.57 13 174803 262 42446257
Pulmonary haemorrhage 19.84 11.57 96 174720 11301 42435218
Giardiasis 19.83 11.57 17 174799 524 42445995
Staphylococcal skin infection 19.82 11.57 23 174793 1028 42445491
Dementia 19.81 11.57 23 174793 16457 42430062
Cow pox 19.79 11.57 7 174809 31 42446488
Retching 19.75 11.57 4 174812 7817 42438702
Productive cough 19.75 11.57 127 174689 51440 42395079
Peripheral coldness 19.72 11.57 5 174811 8370 42438149
Hepatitis C virus test 19.60 11.57 8 174808 56 42446463
Necrosis 19.60 11.57 66 174750 6585 42439934
Drug level above therapeutic 19.56 11.57 61 174755 5845 42440674
Cyclosporidium infection 19.55 11.57 6 174810 15 42446504
Gamma-glutamyltransferase increased 19.54 11.57 68 174748 32429 42414090
Vascular hyalinosis 19.49 11.57 10 174806 125 42446394
Meningitis meningococcal 19.47 11.57 9 174807 88 42446431
Blood urine present 19.46 11.57 12 174804 11721 42434798
Arterial rupture 19.46 11.57 17 174799 538 42445981
Hip fracture 19.43 11.57 16 174800 13456 42433063
Oesophageal candidiasis 19.41 11.57 59 174757 5576 42440943
Vascular pseudoaneurysm ruptured 19.41 11.57 16 174800 467 42446052
Penile ulceration 19.39 11.57 20 174796 782 42445737
Acute hepatitis C 19.35 11.57 10 174806 127 42446392
Hepatic artery stenosis 19.34 11.57 11 174805 171 42446348
Gynaecomastia 19.30 11.57 14 174802 12553 42433966
Biliary hamartoma 19.27 11.57 6 174810 16 42446503
Ventricular remodelling 19.21 11.57 9 174807 91 42446428
Epididymitis 19.15 11.57 40 174776 2994 42443525
Papillary renal cell carcinoma 19.11 11.57 14 174802 342 42446177
Arterial disorder 19.08 11.57 25 174791 1267 42445252
Epithelioid mesothelioma 19.06 11.57 5 174811 5 42446514
Bulbar palsy 19.04 11.57 13 174803 283 42446236
Psychotic disorder 19.02 11.57 59 174757 29149 42417370
Neurosyphilis 19.02 11.57 8 174808 61 42446458
Metastases to lymph nodes 19.00 11.57 61 174755 5937 42440582
Rib fracture 18.99 11.57 24 174792 16547 42429972
Oxalosis 18.94 11.57 7 174809 36 42446483
Renal cell carcinoma stage I 18.94 11.57 7 174809 36 42446483
Purtscher retinopathy 18.91 11.57 8 174808 62 42446457
Phospholipidosis 18.91 11.57 8 174808 62 42446457
Meningitis bacterial 18.88 11.57 26 174790 1383 42445136
Metastasis 18.85 11.57 52 174764 4653 42441866
Pneumopericardium 18.82 11.57 10 174806 135 42446384
Antiviral drug level above therapeutic 18.80 11.57 8 174808 63 42446456
Campylobacter infection 18.79 11.57 26 174790 1389 42445130
Varicella virus test positive 18.77 11.57 12 174804 233 42446286
Disorientation 18.76 11.57 81 174735 36308 42410211
Retinal vasculitis 18.74 11.57 18 174798 645 42445874
Acute coronary syndrome 18.68 11.57 20 174796 14845 42431674
Hepatitis C RNA increased 18.65 11.57 13 174803 293 42446226
Ecthyma 18.63 11.57 18 174798 650 42445869
Limb discomfort 18.62 11.57 15 174801 12752 42433767
Palmar-plantar erythrodysaesthesia syndrome 18.61 11.57 35 174781 20547 42425972
Bronchostenosis 18.60 11.57 15 174801 424 42446095
Hypocomplementaemia 18.58 11.57 8 174808 65 42446454
Vanishing bile duct syndrome 18.58 11.57 30 174786 1841 42444678
Second primary malignancy 18.55 11.57 8 174808 9567 42436952
Haemorrhage 18.49 11.57 159 174657 60404 42386115
Psychomotor hyperactivity 18.47 11.57 11 174805 10947 42435572
Parainfluenzae virus infection 18.47 11.57 44 174772 3599 42442920
Pneumonia escherichia 18.40 11.57 18 174798 660 42445859
Haemorrhagic cyst 18.39 11.57 9 174807 101 42446418
Blood uric acid increased 18.36 11.57 22 174794 15525 42430994
Gastrointestinal ulcer 18.35 11.57 30 174786 1860 42444659
Hepatocellular injury 18.29 11.57 44 174772 23634 42422885
Hyposplenism 18.29 11.57 6 174810 20 42446499
Tuberculosis gastrointestinal 18.28 11.57 12 174804 244 42446275
Acute pulmonary histoplasmosis 18.28 11.57 11 174805 191 42446328
Hepatic infection 18.25 11.57 19 174797 751 42445768
Liver disorder 18.22 11.57 92 174724 39552 42406967
Alpha haemolytic streptococcal infection 18.21 11.57 30 174786 1872 42444647
Cytomegalovirus gastrointestinal ulcer 18.16 11.57 9 174807 104 42446415
Tooth hypoplasia 18.11 11.57 12 174804 248 42446271
Liver function test increased 18.09 11.57 34 174782 19964 42426555
Rash erythematous 18.07 11.57 69 174747 32022 42414497
Enterocolitis fungal 18.07 11.57 6 174810 21 42446498
Abdominal infection 18.04 11.57 35 174781 2484 42444035
Inappropriate antidiuretic hormone secretion 18.03 11.57 123 174693 16418 42430101
Hypopnoea 18.00 11.57 5 174811 7877 42438642
Mycobacterium marinum infection 17.98 11.57 16 174800 519 42446000
Human anaplasmosis 17.98 11.57 8 174808 71 42446448
Increased appetite 17.97 11.57 7 174809 8899 42437620
Pneumoretroperitoneum 17.95 11.57 10 174806 149 42446370
Granulomatous liver disease 17.85 11.57 18 174798 685 42445834
Glycosylated haemoglobin increased 17.85 11.57 16 174800 12908 42433611
Cytopenia 17.84 11.57 128 174688 17369 42429150
HIV infection 17.83 11.57 26 174790 1459 42445060
Calciphylaxis 17.80 11.57 23 174793 1150 42445369
Gastroenteritis rotavirus 17.76 11.57 13 174803 317 42446202
Agranulocytosis 17.76 11.57 198 174618 30414 42416105
Cachexia 17.68 11.57 73 174743 8031 42438488
Renal abscess 17.66 11.57 14 174802 386 42446133
Corneal graft rejection 17.65 11.57 7 174809 45 42446474
Blood calcium decreased 17.55 11.57 12 174804 11096 42435423
Rhinitis 17.55 11.57 14 174802 11963 42434556
Renal haemorrhage 17.51 11.57 27 174789 1592 42444927
Pneumococcal infection 17.50 11.57 16 174800 538 42445981
Febrile bone marrow aplasia 17.47 11.57 10 174806 10171 42436348
Spermatozoa progressive motility decreased 17.46 11.57 11 174805 208 42446311
Pneumonia pneumococcal 17.44 11.57 35 174781 2546 42443973
Periodontitis 17.42 11.57 32 174784 2179 42444340
Myocardiac abscess 17.40 11.57 7 174809 47 42446472
Cytomegalovirus myocarditis 17.39 11.57 5 174811 9 42446510
Electrocardiogram abnormal 17.36 11.57 10 174806 10135 42436384
Cytokine storm 17.34 11.57 20 174796 888 42445631
Metapneumovirus pneumonia 17.33 11.57 8 174808 78 42446441
Pyomyositis 17.27 11.57 12 174804 269 42446250
Angina unstable 17.26 11.57 13 174803 11435 42435084
Oral disorder 17.16 11.57 51 174765 4761 42441758
Restless legs syndrome 17.14 11.57 9 174807 9605 42436914
Accident 17.12 11.57 3 174813 6500 42440019
Cytomegalovirus syndrome 17.10 11.57 9 174807 119 42446400
Ejection fraction decreased 17.10 11.57 41 174775 22046 42424473
Encephalitis fungal 17.09 11.57 11 174805 216 42446303
Lower respiratory tract infection 17.08 11.57 99 174717 41107 42405412
Spleen atrophy 17.05 11.57 5 174811 10 42446509
Nosocomial infection 17.03 11.57 25 174791 1411 42445108
Thirst 17.03 11.57 8 174808 9100 42437419
Trench fever 17.03 11.57 7 174809 50 42446469
Hypernatraemia 17.00 11.57 10 174806 10022 42436497
Cytomegalovirus mucocutaneous ulcer 16.98 11.57 8 174808 82 42446437
Hyperparathyroidism tertiary 16.91 11.57 7 174809 51 42446468
Severe acute respiratory syndrome 16.90 11.57 9 174807 122 42446397
Reperfusion injury 16.89 11.57 8 174808 83 42446436
VIth nerve paralysis 16.87 11.57 20 174796 915 42445604
Molluscum contagiosum 16.85 11.57 13 174803 344 42446175
Achromobacter infection 16.80 11.57 10 174806 170 42446349
Blood lactic acid increased 16.75 11.57 6 174810 8033 42438486
Lung squamous cell carcinoma stage II 16.73 11.57 5 174811 11 42446508
Bone infarction 16.67 11.57 12 174804 285 42446234
Skin induration 16.60 11.57 29 174787 1898 42444621
Endoscopy upper gastrointestinal tract abnormal 16.57 11.57 7 174809 54 42446465
Cutaneous T-cell lymphoma stage II 16.54 11.57 6 174810 29 42446490
Enterobacter bacteraemia 16.53 11.57 16 174800 579 42445940
Hepatic necrosis 16.43 11.57 44 174772 3869 42442650
Localised infection 16.43 11.57 37 174779 20336 42426183
Abdominal wall abscess 16.39 11.57 17 174799 669 42445850
Hepatic failure 16.36 11.57 233 174583 37867 42408652
Protein-losing gastroenteropathy 16.35 11.57 14 174802 431 42446088
Rotavirus infection 16.34 11.57 15 174801 507 42446012
Pleomorphic malignant fibrous histiocytoma 16.22 11.57 6 174810 31 42446488
Oesophageal atresia 16.17 11.57 15 174801 514 42446005
Intervertebral disc protrusion 16.16 11.57 13 174803 11059 42435460
Arterial fibrosis 16.15 11.57 5 174811 13 42446506
Pulmonary thrombosis 16.13 11.57 7 174809 8341 42438178
Blood immunoglobulin A decreased 16.13 11.57 17 174799 682 42445837
SARS-CoV-2 viraemia 16.10 11.57 8 174808 93 42446426
Viral load increased 16.07 11.57 37 174779 2960 42443559
Cardiac valve abscess 16.06 11.57 6 174810 32 42446487
Hypertensive emergency 15.99 11.57 23 174793 1274 42445245
Diarrhoea 15.99 11.57 1651 173165 459198 41987321
Chronic hepatitis C 15.93 11.57 15 174801 524 42445995
Viral cardiomyopathy 15.91 11.57 6 174810 33 42446486
Granulomatous dermatitis 15.90 11.57 12 174804 307 42446212
Leukaemia recurrent 15.86 11.57 28 174788 1848 42444671
Therapeutic response unexpected 15.82 11.57 14 174802 11367 42435152
Emotional distress 15.79 11.57 26 174790 16067 42430452
Bartonellosis 15.76 11.57 6 174810 34 42446485
Schwannoma 15.76 11.57 6 174810 34 42446485
Ventricular extrasystoles 15.76 11.57 19 174797 13371 42433148
Hiccups 15.72 11.57 16 174800 12155 42434364
Malabsorption 15.72 11.57 35 174781 2738 42443781
Parvovirus B19 test positive 15.71 11.57 9 174807 142 42446377
Capnocytophaga infection 15.71 11.57 9 174807 142 42446377
Anaplastic large cell lymphoma T- and null-cell types 15.65 11.57 9 174807 143 42446376
Ureteritis 15.65 11.57 9 174807 143 42446376
Nephritis haemorrhagic 15.63 11.57 5 174811 15 42446504
Skin abrasion 15.57 11.57 7 174809 8168 42438351
Respiratory tract congestion 15.55 11.57 6 174810 7672 42438847
Vascular graft complication 15.54 11.57 9 174807 145 42446374
Antisynthetase syndrome 15.54 11.57 9 174807 145 42446374
Latent autoimmune diabetes in adults 15.54 11.57 9 174807 145 42446374
Dysstasia 15.53 11.57 21 174795 14065 42432454
Hallucination, visual 15.50 11.57 40 174776 20980 42425539
Sebaceous gland disorder 15.48 11.57 6 174810 36 42446483
Face oedema 15.45 11.57 20 174796 13646 42432873
Lymphadenopathy mediastinal 15.44 11.57 38 174778 3173 42443346
Cerebral haemorrhage 15.42 11.57 95 174721 38871 42407648
Abdominal abscess 15.41 11.57 51 174765 5042 42441477
Hepatitis viral 15.40 11.57 18 174798 811 42445708
Biopsy kidney 15.36 11.57 7 174809 66 42446453
Lung squamous cell carcinoma stage IV 15.34 11.57 6 174810 37 42446482
Coma 15.30 11.57 143 174673 53411 42393108
Kidney rupture 15.29 11.57 10 174806 202 42446317
Multiple sclerosis 15.28 11.57 6 174810 7592 42438927
Aplastic anaemia 15.28 11.57 95 174721 12289 42434230
BK polyomavirus test positive 15.27 11.57 7 174809 67 42446452
Transfusion associated graft versus host disease 15.25 11.57 4 174812 4 42446515
Sinus perforation 15.25 11.57 4 174812 4 42446515
Insulin resistant diabetes 15.25 11.57 4 174812 4 42446515
Exposure during pregnancy 15.24 11.57 8 174808 8540 42437979
Lung consolidation 15.24 11.57 61 174755 6616 42439903
Brain herniation 15.23 11.57 49 174767 4774 42441745
Human herpes virus 8 test positive 15.20 11.57 6 174810 38 42446481
Alopecia 15.19 11.57 65 174751 29211 42417308
Arteritis coronary 15.18 11.57 7 174809 68 42446451
Cardiac murmur 15.17 11.57 18 174798 12757 42433762
Ankylosing spondylitis 15.16 11.57 5 174811 7051 42439468
Hyperaesthesia 15.13 11.57 3 174813 5949 42440570
Wound evisceration 15.12 11.57 8 174808 107 42446412
Bronchitis bacterial 15.11 11.57 19 174797 924 42445595
Typhoid fever 15.09 11.57 7 174809 69 42446450
Gingival pain 15.07 11.57 8 174808 8486 42438033
Antibody test positive 15.07 11.57 17 174799 737 42445782
Nephrosclerosis 15.06 11.57 20 174796 1027 42445492
Feeding disorder 15.06 11.57 8 174808 8483 42438036
Gastric disorder 15.03 11.57 16 174800 11906 42434613
Mental impairment 15.01 11.57 17 174799 12300 42434219
Bundle branch block left 14.99 11.57 4 174812 6472 42440047
Respiratory distress 14.98 11.57 248 174568 41572 42404947
Abscess 14.97 11.57 105 174711 14143 42432376
Anastomotic stenosis 14.97 11.57 13 174803 408 42446111
Autoimmune anaemia 14.95 11.57 5 174811 18 42446501
Angiosarcoma recurrent 14.95 11.57 5 174811 18 42446501
Blood calcium increased 14.94 11.57 8 174808 8446 42438073
Right ventricular diastolic collapse 14.92 11.57 7 174809 71 42446448
Sinus congestion 14.91 11.57 5 174811 6975 42439544
Small intestine adenocarcinoma 14.83 11.57 10 174806 213 42446306
Genitourinary tract infection 14.80 11.57 8 174808 112 42446407
Kidney infection 14.78 11.57 61 174755 6709 42439810
Herpes zoster reactivation 14.76 11.57 13 174803 416 42446103
Spinal stenosis 14.75 11.57 4 174812 6402 42440117
Splenic peliosis 14.74 11.57 5 174811 19 42446500
Hyperoxaluria 14.72 11.57 9 174807 161 42446358
Myelitis 14.69 11.57 20 174796 1052 42445467
Limbic encephalitis 14.68 11.57 13 174803 419 42446100
Pancreatic fistula 14.67 11.57 7 174809 74 42446445
Electrocardiogram QRS complex prolonged 14.66 11.57 3 174813 5820 42440699
Cardiovascular disorder 14.66 11.57 20 174796 13345 42433174
Haematotoxicity 14.66 11.57 86 174730 10899 42435620
Ejection fraction abnormal 14.58 11.57 22 174794 1273 42445246
Visual field defect 14.55 11.57 49 174767 4889 42441630
Colitis herpes 14.54 11.57 5 174811 20 42446499
T-cell lymphoma stage IV 14.53 11.57 9 174807 165 42446354
Renal infarct 14.52 11.57 27 174789 1856 42444663
Mydriasis 14.50 11.57 9 174807 8761 42437758
Cholangiocarcinoma 14.48 11.57 25 174791 1621 42444898
Intestinal villi atrophy 14.48 11.57 9 174807 166 42446353
Nerve conduction studies abnormal 14.46 11.57 6 174810 44 42446475
Diverticulitis intestinal perforated 14.46 11.57 11 174805 285 42446234
Device dislocation 14.46 11.57 7 174809 7824 42438695
Leukoencephalopathy 14.45 11.57 49 174767 4905 42441614
Decubitus ulcer 14.43 11.57 13 174803 10464 42436055
Hepatic haematoma 14.42 11.57 13 174803 429 42446090
Mastication disorder 14.37 11.57 26 174790 1750 42444769
Platelet production decreased 14.36 11.57 4 174812 6 42446513
Pyuria 14.35 11.57 19 174797 973 42445546
Throat tightness 14.35 11.57 11 174805 9588 42436931
Retinal coloboma 14.35 11.57 5 174811 21 42446498
Dizziness postural 14.34 11.57 7 174809 7788 42438731
Nephrogenic systemic fibrosis 14.33 11.57 39 174777 3462 42443057
Leiomyosarcoma 14.29 11.57 9 174807 170 42446349
Faecaloma 14.28 11.57 4 174812 6266 42440253
Pulmonary vasculitis 14.26 11.57 4 174812 6262 42440257
Serositis 14.23 11.57 11 174805 292 42446227
Bacteriuria 14.23 11.57 11 174805 292 42446227
Sexual dysfunction 14.21 11.57 5 174811 6770 42439749
Urinary fistula 14.20 11.57 8 174808 122 42446397
Pseudomonal sepsis 14.18 11.57 44 174772 4205 42442314
Enamel anomaly 14.13 11.57 10 174806 231 42446288
Tuberculosis of genitourinary system 14.12 11.57 7 174809 81 42446438
Tooth disorder 14.09 11.57 17 174799 11962 42434557
Vestibular nystagmus 13.98 11.57 4 174812 7 42446512
Pericoronitis 13.98 11.57 4 174812 7 42446512
Hypertrophic osteoarthropathy 13.97 11.57 7 174809 83 42446436
Urine protein/creatinine ratio increased 13.96 11.57 17 174799 800 42445719
Herpes simplex encephalitis 13.94 11.57 12 174804 372 42446147
Ureteric obstruction 13.90 11.57 22 174794 1327 42445192
Wound 13.87 11.57 31 174785 17086 42429433
Restrictive allograft syndrome 13.81 11.57 5 174811 24 42446495
Hernia 13.80 11.57 15 174801 11058 42435461
Anomalous pulmonary venous connection 13.76 11.57 8 174808 130 42446389
Large intestinal stenosis 13.72 11.57 27 174789 1936 42444583
Dehiscence 13.65 11.57 15 174801 631 42445888
Urinary bladder toxicity 13.65 11.57 5 174811 25 42446494
Renal tuberculosis 13.65 11.57 5 174811 25 42446494
Muscle neoplasm 13.64 11.57 4 174812 8 42446511
High grade B-cell lymphoma Burkitt-like lymphoma stage IV 13.64 11.57 4 174812 8 42446511
Bacterial abdominal infection 13.64 11.57 4 174812 8 42446511
Wound infection staphylococcal 13.62 11.57 23 174793 1465 42445054
Type 3 diabetes mellitus 13.61 11.57 7 174809 88 42446431
Complement factor C3 decreased 13.60 11.57 6 174810 52 42446467
Cryoglobulinaemia 13.60 11.57 14 174802 546 42445973
Coronary artery occlusion 13.59 11.57 15 174801 10982 42435537
Pharyngeal oedema 13.58 11.57 4 174812 6064 42440455
Cellulitis orbital 13.58 11.57 13 174803 464 42446055
Conjunctivitis 13.56 11.57 20 174796 12919 42433600
Sebaceous hyperplasia 13.54 11.57 8 174808 134 42446385
Aortic valve disease mixed 13.54 11.57 7 174809 89 42446430
Aortic pseudoaneurysm 13.51 11.57 6 174810 53 42446466
Lymphatic system neoplasm 13.50 11.57 3 174813 0 42446519
Endotoxaemia 13.50 11.57 3 174813 0 42446519
Bacterial abscess central nervous system 13.50 11.57 3 174813 0 42446519
Mononucleosis syndrome 13.49 11.57 8 174808 135 42446384
Infected lymphocele 13.49 11.57 5 174811 26 42446493
Myasthenia gravis crisis 13.49 11.57 17 174799 829 42445690
Steatohepatitis 13.44 11.57 13 174803 470 42446049
Tooth extraction 13.44 11.57 3 174813 5477 42441042
Gastrointestinal tract adenoma 13.43 11.57 11 174805 318 42446201
Prophylaxis against transplant rejection 13.41 11.57 6 174810 54 42446465
Corneal lesion 13.40 11.57 7 174809 91 42446428
Oesophagitis ulcerative 13.37 11.57 18 174798 937 42445582
Progressive bulbar palsy 13.33 11.57 5 174811 27 42446492
Rhabdoid tumour 13.33 11.57 5 174811 27 42446492
Secondary immunodeficiency 13.33 11.57 17 174799 839 42445680
Mantle cell lymphoma stage IV 13.31 11.57 6 174810 55 42446464
Pemphigus 13.31 11.57 27 174789 1979 42444540
Myasthenia gravis 13.26 11.57 29 174787 16108 42430411
Anti-erythropoietin antibody negative 13.26 11.57 9 174807 194 42446325
Systemic scleroderma 13.25 11.57 14 174802 563 42445956
Product prescribing issue 13.22 11.57 59 174757 6714 42439805
Gastric perforation 13.21 11.57 35 174781 3058 42443461
Biliary ischaemia 13.21 11.57 7 174809 94 42446425
Skin haemorrhage 13.17 11.57 8 174808 7877 42438642
Type III immune complex mediated reaction 13.15 11.57 14 174802 568 42445951
Haemophilus infection 13.14 11.57 23 174793 1508 42445011
Blood potassium increased 13.12 11.57 36 174780 18500 42428019
Eye disorder 13.12 11.57 17 174799 11595 42434924
Soft tissue infection 13.09 11.57 32 174784 2661 42443858
Blood pressure abnormal 13.08 11.57 13 174803 9985 42436534
Myocarditis toxoplasmal 13.04 11.57 6 174810 58 42446461
Endotoxic shock 13.03 11.57 4 174812 10 42446509
Gastroenteritis listeria 13.03 11.57 4 174812 10 42446509
Ureteric fistula 13.03 11.57 4 174812 10 42446509
Haemorrhoids 13.02 11.57 32 174784 17065 42429454
Opsoclonus myoclonus 13.01 11.57 7 174809 97 42446422
Philadelphia positive chronic myeloid leukaemia 12.99 11.57 8 174808 145 42446374
Priapism 12.98 11.57 5 174811 6402 42440117
Cryptococcal meningoencephalitis 12.98 11.57 9 174807 201 42446318
Portal fibrosis 12.95 11.57 11 174805 335 42446184
Crying 12.94 11.57 5 174811 6389 42440130
Pseudomembranous colitis 12.92 11.57 35 174781 3098 42443421
Bronchopleural fistula 12.90 11.57 15 174801 672 42445847
Optic perineuritis 12.90 11.57 5 174811 30 42446489
Agnosia 12.89 11.57 7 174809 99 42446420
Duodenitis 12.88 11.57 51 174765 5505 42441014
Shock 12.87 11.57 179 174637 28942 42417577
Metapneumovirus infection 12.86 11.57 20 174796 1188 42445331
Femoral nerve palsy 12.86 11.57 6 174810 60 42446459
Sneezing 12.84 11.57 5 174811 6358 42440161
Peripheral arterial occlusive disease 12.80 11.57 6 174810 6832 42439687
Blood thyroid stimulating hormone increased 12.77 11.57 3 174813 5289 42441230
Atypical mycobacterial lymphadenitis 12.76 11.57 4 174812 11 42446508
Choroidal osteoma 12.76 11.57 5 174811 31 42446488
External ear disorder 12.76 11.57 5 174811 31 42446488
Kaposi sarcoma inflammatory cytokine syndrome 12.75 11.57 8 174808 150 42446369
Orbital infection 12.69 11.57 6 174810 62 42446457
Diabetic nephropathy 12.66 11.57 29 174787 2312 42444207
Fibrosis 12.65 11.57 34 174782 2996 42443523
Conjunctival disorder 12.64 11.57 7 174809 103 42446416
Lymphocytosis 12.64 11.57 34 174782 2997 42443522
Intestinal metastasis 12.62 11.57 11 174805 347 42446172
Disseminated coccidioidomycosis 12.59 11.57 7 174809 104 42446415
Pericardial effusion 12.55 11.57 179 174637 29096 42417423
Hiatus hernia 12.55 11.57 10 174806 8550 42437969
Muscle twitching 12.55 11.57 18 174798 11762 42434757
Lymph gland infection 12.53 11.57 9 174807 213 42446306
Listeria encephalitis 12.53 11.57 6 174810 64 42446455
Osteomyelitis 12.53 11.57 122 174694 18101 42428418
Plasma cell myeloma recurrent 12.51 11.57 4 174812 5753 42440766
Anorectal infection bacterial 12.51 11.57 4 174812 12 42446507
Pterygium colli 12.51 11.57 4 174812 12 42446507
Ovarian cancer metastatic 12.51 11.57 4 174812 12 42446507
Hypothermia 12.48 11.57 20 174796 12495 42434024
Granulomatous rosacea 12.44 11.57 8 174808 157 42446362
Myeloma cast nephropathy 12.41 11.57 7 174809 107 42446412
Ischaemic stroke 12.39 11.57 48 174768 22185 42424334
Colon dysplasia 12.39 11.57 9 174807 217 42446302
Restrictive pulmonary disease 12.38 11.57 21 174795 1342 42445177
Anosmia 12.36 11.57 3 174813 5173 42441346
Endocarditis enterococcal 12.35 11.57 7 174809 108 42446411
Drug-induced liver injury 12.35 11.57 99 174717 38174 42408345
Neurosarcoidosis 12.35 11.57 9 174807 218 42446301
Eye irritation 12.35 11.57 17 174799 11301 42435218
Sinus disorder 12.32 11.57 9 174807 8041 42438478
Antiphospholipid syndrome 12.30 11.57 14 174802 613 42445906
Renal lymphocele 12.29 11.57 6 174810 67 42446452
Lung squamous cell carcinoma metastatic 12.29 11.57 6 174810 67 42446452
Granulomatosis with polyangiitis 12.27 11.57 22 174794 1470 42445049
Oesophageal tuberculosis 12.27 11.57 4 174812 13 42446506
Iliac artery disease 12.27 11.57 4 174812 13 42446506
Liver transplant failure 12.24 11.57 7 174809 110 42446409
Supraventricular tachycardia 12.22 11.57 20 174796 12388 42434131
Myocardial ischaemia 12.20 11.57 35 174781 17727 42428792
Angiopathy 12.17 11.57 49 174767 5328 42441191
Product administered to patient of inappropriate age 12.10 11.57 45 174771 4716 42441803
Brain oedema 12.06 11.57 111 174705 16216 42430303
Abscess rupture 12.06 11.57 6 174810 70 42446449
Neisseria infection 12.06 11.57 6 174810 70 42446449
Necrotising bronchiolitis 12.04 11.57 4 174812 14 42446505
Oral herpes 12.04 11.57 62 174754 7482 42439037
Hepatitis B 12.02 11.57 57 174759 6654 42439865
Thyroid stimulating hormone deficiency 12.01 11.57 5 174811 37 42446482
Neurocryptococcosis 12.01 11.57 5 174811 37 42446482
Chest wall abscess 12.00 11.57 9 174807 228 42446291
Anastomotic haemorrhage 11.97 11.57 9 174807 229 42446290
Portal hypertension 11.96 11.57 45 174771 4742 42441777
Blood pressure diastolic decreased 11.92 11.57 15 174801 10360 42436159
Clostridial infection 11.91 11.57 39 174777 3835 42442684
Bacillus infection 11.91 11.57 15 174801 731 42445788
Retinal disorder 11.88 11.57 19 174797 1156 42445363
Encephalitis brain stem 11.88 11.57 8 174808 170 42446349
Embolic stroke 11.88 11.57 3 174813 5037 42441482
Renal artery occlusion 11.86 11.57 7 174809 117 42446402
Coeliac disease 11.86 11.57 17 174799 939 42445580
Listeriosis 11.85 11.57 21 174795 1390 42445129
Interleukin-2 receptor increased 11.84 11.57 8 174808 171 42446348
Upper limb fracture 11.83 11.57 4 174812 5552 42440967
Muscle tightness 11.82 11.57 4 174812 5549 42440970
Blood immunoglobulin G decreased 11.78 11.57 28 174788 2286 42444233
Parathyroid tumour benign 11.77 11.57 9 174807 235 42446284
CNS ventriculitis 11.76 11.57 11 174805 381 42446138
Human herpes virus 6 serology positive 11.72 11.57 8 174808 174 42446345
Seborrhoeic keratosis 11.70 11.57 23 174793 1648 42444871
Ectropion 11.68 11.57 8 174808 175 42446344
Otitis externa 11.66 11.57 19 174797 1175 42445344
Iris neoplasm 11.63 11.57 4 174812 16 42446503
Adhesiolysis 11.63 11.57 4 174812 16 42446503
Renal artery perforation 11.63 11.57 4 174812 16 42446503
Herpes simplex viraemia 11.61 11.57 7 174809 122 42446397
Pneumonia staphylococcal 11.60 11.57 36 174780 3440 42443079
Microangiopathy 11.60 11.57 23 174793 1659 42444860
Eructation 11.59 11.57 4 174812 5482 42441037
Immune effector cell-associated neurotoxicity syndrome 11.59 11.57 13 174803 9448 42437071
Cardiogenic shock 11.59 11.57 92 174724 35548 42410971
Intervertebral disc degeneration 11.59 11.57 8 174808 7359 42439160
Fibrosarcoma 11.58 11.57 5 174811 41 42446478

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Transplant rejection 6486.72 10.59 2683 408269 21884 110156463
Cytomegalovirus infection 6009.83 10.59 3258 407694 51186 110127161
Post transplant lymphoproliferative disorder 3635.79 10.59 1560 409392 14053 110164294
Off label use 2871.43 10.59 12058 398894 1488127 108690220
Polyomavirus-associated nephropathy 2822.91 10.59 1085 409867 7116 110171231
Kidney transplant rejection 2351.87 10.59 1062 409890 10925 110167422
Product use in unapproved indication 2195.13 10.59 5012 405940 442365 109735982
BK virus infection 2138.61 10.59 1022 409930 12084 110166263
Epstein-Barr virus infection 2104.00 10.59 1135 409817 17603 110160744
Transplant dysfunction 2057.64 10.59 868 410084 7460 110170887
Cytomegalovirus viraemia 1994.56 10.59 1076 409876 16688 110161659
Acute graft versus host disease 1874.95 10.59 929 410023 11952 110166395
Thrombotic microangiopathy 1853.80 10.59 1224 409728 27925 110150422
Cytomegalovirus infection reactivation 1812.26 10.59 1021 409931 17312 110161035
Complications of transplanted kidney 1619.26 10.59 709 410243 6733 110171614
Acute graft versus host disease in skin 1502.36 10.59 754 410198 9986 110168361
Immunosuppressant drug level increased 1400.10 10.59 740 410212 10984 110167363
Adenovirus infection 1367.21 10.59 713 410239 10281 110168066
Fall 1250.55 10.59 348 410604 603134 109575213
Aspergillus infection 1226.85 10.59 904 410048 24712 110153635
Graft versus host disease 1162.57 10.59 776 410176 18030 110160317
Drug ineffective for unapproved indication 1082.26 10.59 1605 409347 101233 110077114
Polyomavirus viraemia 1073.12 10.59 425 410527 3049 110175298
Chronic graft versus host disease 1064.81 10.59 574 410378 8883 110169464
Pneumocystis jirovecii pneumonia 1062.96 10.59 1034 409918 41701 110136646
Graft versus host disease in skin 999.84 10.59 526 410426 7728 110170619
Graft versus host disease in gastrointestinal tract 964.37 10.59 528 410424 8440 110169907
Nocardiosis 961.01 10.59 496 410456 6990 110171357
Transplant failure 951.58 10.59 450 410502 5185 110173162
Parvovirus B19 infection 948.12 10.59 369 410583 2512 110175835
Pain 881.51 10.59 1369 409583 953586 109224761
Posterior reversible encephalopathy syndrome 866.01 10.59 832 410120 33029 110145318
Multiple organ dysfunction syndrome 863.44 10.59 1807 409145 149903 110028444
Constipation 832.42 10.59 160 410792 357626 109820721
Completed suicide 821.16 10.59 16 410936 242365 109935982
Nausea 814.66 10.59 2154 408798 1233536 108944811
Bronchopulmonary aspergillosis 807.99 10.59 757 410195 29106 110149241
Fatigue 804.29 10.59 2116 408836 1213842 108964505
Mucormycosis 803.91 10.59 498 410454 10130 110168217
Liver transplant rejection 799.92 10.59 357 410595 3561 110174786
COVID-19 787.21 10.59 2346 408606 242714 109935633
Chronic allograft nephropathy 780.92 10.59 295 410657 1831 110176516
Klebsiella infection 769.67 10.59 620 410332 19389 110158958
Nephropathy toxic 767.47 10.59 709 410243 26769 110151578
Varicella zoster virus infection 757.68 10.59 401 410551 5967 110172380
Renal transplant failure 755.58 10.59 307 410645 2373 110175974
Dyspnoea 753.28 10.59 1898 409054 1104974 109073373
Phaeohyphomycosis 736.90 10.59 267 410685 1447 110176900
Pseudomonas infection 728.62 10.59 693 410259 27160 110151187
Acute graft versus host disease in intestine 727.82 10.59 375 410577 5264 110173083
Cytomegalovirus colitis 724.29 10.59 403 410549 6658 110171689
Diffuse large B-cell lymphoma 679.05 10.59 524 410428 15374 110162973
Escherichia infection 650.62 10.59 607 410345 23209 110155138
Heart transplant rejection 644.42 10.59 253 410699 1768 110176579
Dizziness 637.54 10.59 1007 409945 697186 109481161
Delayed graft function 619.37 10.59 307 410645 3950 110174397
Cystitis haemorrhagic 609.77 10.59 442 410510 11767 110166580
Death 606.39 10.59 1042 409910 697827 109480520
Septic shock 603.52 10.59 1608 409344 155920 110022427
Disease recurrence 602.73 10.59 923 410029 59861 110118486
Smooth muscle cell neoplasm 602.73 10.59 219 410733 1198 110177149
Drug abuse 599.70 10.59 12 410940 177399 110000948
Enterococcal infection 585.31 10.59 534 410418 19832 110158515
Epstein-Barr virus associated lymphoproliferative disorder 584.41 10.59 307 410645 4495 110173852
Leukopenia 574.23 10.59 1523 409429 147268 110031079
Trichodysplasia spinulosa 563.89 10.59 193 410759 857 110177490
Renal impairment 562.75 10.59 1759 409193 186686 109991661
Acute respiratory distress syndrome 561.89 10.59 832 410120 52366 110125981
Malacoplakia 553.12 10.59 199 410753 1053 110177294
Histoplasmosis disseminated 551.95 10.59 276 410676 3623 110174724
Haemophagocytic lymphohistiocytosis 548.44 10.59 631 410321 30928 110147419
Strongyloidiasis 548.41 10.59 298 410654 4688 110173659
Back pain 543.27 10.59 355 410597 370641 109807706
Product dose omission issue 540.10 10.59 260 410692 321522 109856825
JC virus infection 534.62 10.59 299 410653 4991 110173356
Cryptococcosis 526.70 10.59 283 410669 4348 110173999
Human herpesvirus 6 infection 522.30 10.59 318 410634 6263 110172084
Focal segmental glomerulosclerosis 521.59 10.59 271 410681 3874 110174473
Injection site pain 517.96 10.59 37 410915 177885 110000462
Brain abscess 513.82 10.59 318 410634 6456 110171891
Chronic graft versus host disease in skin 513.53 10.59 232 410720 2387 110175960
Pulmonary nocardiosis 496.90 10.59 227 410725 2402 110175945
Hypotension 486.88 10.59 746 410206 523103 109655244
Meningitis cryptococcal 486.28 10.59 271 410681 4491 110173856
Herpes simplex 485.91 10.59 430 410522 15334 110163013
Pneumonia cytomegaloviral 476.25 10.59 306 410646 6648 110171699
Hepatitis E 464.21 10.59 257 410695 4202 110174145
Epstein-Barr viraemia 459.00 10.59 237 410715 3342 110175005
Arthralgia 442.59 10.59 1455 409497 778177 109400170
Infection reactivation 438.02 10.59 240 410712 3841 110174506
Human herpesvirus 8 infection 435.59 10.59 187 410765 1684 110176663
Pain in extremity 425.05 10.59 723 410229 486395 109691952
Aplasia pure red cell 420.67 10.59 321 410631 9257 110169090
Headache 413.05 10.59 1782 409170 880595 109297752
Immunosuppressant drug level decreased 412.56 10.59 203 410749 2568 110175779
Hypogammaglobulinaemia 408.50 10.59 436 410516 19640 110158707
Cerebral toxoplasmosis 405.65 10.59 209 410743 2933 110175414
Respiratory failure 399.74 10.59 1723 409229 213609 109964738
Therapy non-responder 392.45 10.59 1382 409570 155925 110022422
Acute graft versus host disease in liver 391.01 10.59 186 410766 2173 110176174
Viraemia 390.61 10.59 223 410729 3879 110174468
Sciatica 390.61 10.59 979 409973 91420 110086927
Somnolence 389.41 10.59 320 410632 297129 109881218
Proteinuria 388.72 10.59 602 410350 39416 110138931
Feeling abnormal 385.32 10.59 98 410854 180613 109997734
Syncope 384.41 10.59 136 410816 202400 109975947
Hyperhidrosis 379.81 10.59 112 410840 187186 109991161
Kidney fibrosis 379.08 10.59 224 410728 4168 110174179
Alternaria infection 373.79 10.59 141 410811 871 110177476
Renal tubular injury 373.40 10.59 197 410755 2911 110175436
COVID-19 pneumonia 372.38 10.59 567 410385 36576 110141771
Human polyomavirus infection 370.45 10.59 165 410787 1637 110176710
Rash 363.60 10.59 1692 409260 819272 109359075
Progressive multifocal leukoencephalopathy 361.59 10.59 455 410497 24501 110153846
Disseminated cryptococcosis 361.20 10.59 183 410769 2474 110175873
Inappropriate schedule of product administration 356.40 10.59 155 410797 203482 109974865
Lung transplant rejection 353.26 10.59 163 410789 1768 110176579
Vaccination failure 350.64 10.59 176 410776 2330 110176017
Graft loss 350.12 10.59 145 410807 1183 110177164
Central nervous system lymphoma 346.13 10.59 186 410766 2858 110175489
Ovarian cyst 340.59 10.59 334 410618 13596 110164751
Toxoplasmosis 338.05 10.59 187 410765 3052 110175295
Asthenia 336.63 10.59 1368 409584 687631 109490716
Renal tubular atrophy 333.68 10.59 165 410787 2111 110176236
Cryptosporidiosis infection 332.77 10.59 134 410818 1009 110177338
Renal tubular necrosis 332.44 10.59 484 410468 29991 110148356
Drug ineffective 332.13 10.59 7679 403273 1512861 108665486
Histoplasmosis 331.76 10.59 179 410773 2774 110175573
Mycobacterial infection 331.59 10.59 206 410746 4211 110174136
Venoocclusive liver disease 330.35 10.59 342 410610 14865 110163482
Intentional overdose 325.98 10.59 51 410901 132450 110045897
Chest discomfort 317.69 10.59 124 410828 173724 110004623
Pulmonary mucormycosis 316.09 10.59 156 410796 1987 110176360
Palpitations 308.87 10.59 103 410849 159109 110019238
Pneumatosis intestinalis 308.47 10.59 255 410697 8274 110170073
Drug resistance 308.29 10.59 661 410291 55713 110122634
West Nile viral infection 306.96 10.59 132 410820 1194 110177153
Chronic obstructive pulmonary disease 305.65 10.59 27 410925 109131 110069216
Staphylococcal infection 302.88 10.59 748 410204 69196 110109151
Malignant neoplasm progression 300.54 10.59 136 410816 174431 110003916
Erythema 299.39 10.59 386 410566 291061 109887286
Blastomycosis 296.10 10.59 123 410829 1012 110177335
Encephalitis viral 295.84 10.59 167 410785 2840 110175507
Viral haemorrhagic cystitis 295.05 10.59 174 410778 3225 110175122
Malaise 293.44 10.59 1391 409561 670428 109507919
Injection site erythema 291.04 10.59 14 410938 94162 110084185
Renal graft infection 282.17 10.59 107 410845 672 110177675
Vomiting 279.80 10.59 2109 408843 908566 109269781
Cytomegalovirus test positive 276.91 10.59 221 410731 6815 110171532
Stenotrophomonas infection 276.53 10.59 205 410747 5653 110172694
Lupus nephritis 275.85 10.59 187 410765 4458 110173889
Cardiac failure congestive 273.76 10.59 109 410843 150891 110027456
Mycobacterium haemophilum infection 268.55 10.59 101 410851 618 110177729
Bradycardia 267.96 10.59 121 410831 155396 110022951
Loss of consciousness 267.15 10.59 203 410749 196103 109982244
Swollen joint count increased 263.55 10.59 796 410156 82865 110095482
Dehydration 259.39 10.59 398 410554 279113 109899234
Bacteraemia 258.70 10.59 520 410432 41870 110136477
Treatment failure 257.06 10.59 1838 409114 275396 109902951
Epstein-Barr virus infection reactivation 255.94 10.59 170 410782 3914 110174433
Myocardial infarction 255.86 10.59 203 410749 191880 109986467
Cytomegalovirus chorioretinitis 255.47 10.59 212 410740 6916 110171431
Pathogen resistance 252.53 10.59 320 410632 17352 110160995
Pruritus 252.16 10.59 1207 409745 580353 109597994
Cerebrovascular accident 251.16 10.59 184 410768 181100 109997247
Hepatitis C 250.42 10.59 270 410682 12303 110166044
White blood cell count decreased 250.13 10.59 290 410662 229100 109949247
Scedosporium infection 248.58 10.59 139 410813 2319 110176028
Fungal skin infection 248.23 10.59 210 410742 7039 110171308
Candida infection 247.80 10.59 550 410402 47459 110130888
Blood pressure increased 246.43 10.59 361 410591 258012 109920335
Squamous cell carcinoma of skin 243.44 10.59 310 410642 16893 110161454
Disseminated varicella zoster virus infection 243.34 10.59 111 410841 1170 110177177
Stress 242.88 10.59 48 410904 105300 110073047
Overdose 236.62 10.59 313 410639 233481 109944866
Systemic mycosis 236.61 10.59 158 410794 3671 110174676
Cytomegalovirus gastrointestinal infection 235.65 10.59 92 410860 632 110177715
Autoimmune disorder 235.14 10.59 653 410299 64830 110113517
Neutrophil count decreased 234.99 10.59 78 410874 120863 110057484
Suicide attempt 234.44 10.59 49 410903 103345 110075002
Cough 233.16 10.59 904 410048 460737 109717610
Deep vein thrombosis postoperative 232.72 10.59 611 410341 58680 110119667
Electrocardiogram QT prolonged 230.49 10.59 60 410892 108900 110069447
Epstein-Barr virus associated lymphoma 226.96 10.59 115 410837 1555 110176792
Disseminated blastomycosis 225.25 10.59 80 410872 405 110177942
Balance disorder 225.03 10.59 76 410876 116484 110061863
Hypoglycaemia 221.90 10.59 77 410875 116027 110062320
Sepsis 221.72 10.59 2020 408932 325326 109853021
Bacillary angiomatosis 221.15 10.59 74 410878 302 110178045
Acne 220.04 10.59 424 410528 33096 110145251
Hypokalaemia 219.79 10.59 212 410740 182236 109996111
Complications of transplanted lung 217.83 10.59 86 410866 611 110177736
End stage renal disease 215.52 10.59 328 410624 21145 110157202
Injection site reaction 215.22 10.59 36 410916 89034 110089313
Haemolytic uraemic syndrome 214.38 10.59 165 410787 4820 110173527
Drug level increased 213.69 10.59 517 410435 47202 110131145
Lymphoproliferative disorder 212.76 10.59 192 410760 7026 110171321
Complications of transplanted heart 212.19 10.59 76 410876 396 110177951
Road traffic accident 211.27 10.59 875 410077 106523 110071824
Papilloma viral infection 211.05 10.59 119 410833 2019 110176328
Neutrophil Pelger-Huet anomaly present 209.41 10.59 72 410880 325 110178022
Penicillium infection 205.82 10.59 81 410871 570 110177777
Graft versus host disease in liver 205.65 10.59 123 410829 2342 110176005
Nephrotic syndrome 204.88 10.59 255 410697 13576 110164771
Abdominal distension 204.56 10.59 209 410743 174894 110003453
Lower limb fracture 204.46 10.59 681 410271 74667 110103680
Glomerulonephritis 204.38 10.59 157 410795 4573 110173774
Myalgia 200.26 10.59 323 410629 222058 109956289
Pneumocystis jirovecii infection 198.83 10.59 150 410802 4250 110174097
Atrial fibrillation 196.23 10.59 345 410607 229297 109949050
Wrong technique in product usage process 194.77 10.59 43 410909 87305 110091042
Dry skin 191.40 10.59 80 410872 107573 110070774
Chronic graft versus host disease in liver 191.39 10.59 85 410867 837 110177510
Flushing 190.83 10.59 75 410877 104661 110073686
Cat scratch disease 190.52 10.59 77 410875 586 110177761
Lymphopenia 190.45 10.59 445 410507 39725 110138622
Fungal infection 187.72 10.59 512 410440 50294 110128053
Disseminated tuberculosis 186.40 10.59 154 410798 4992 110173355
Actinic keratosis 184.35 10.59 175 410777 6838 110171509
Lymphocele 184.31 10.59 104 410848 1767 110176580
IgA nephropathy 184.30 10.59 126 410826 3047 110175300
Bacterial sepsis 183.71 10.59 210 410742 10216 110168131
Mycoplasma infection 183.39 10.59 94 410858 1304 110177043
Pneumonia bacterial 183.30 10.59 341 410611 25920 110152427
Chills 182.95 10.59 265 410687 190315 109988032
Cytomegalovirus oesophagitis 182.78 10.59 84 410868 902 110177445
Epidermodysplasia verruciformis 181.22 10.59 67 410885 388 110177959
C-reactive protein 180.23 10.59 368 410584 29963 110148384
Injection site swelling 179.34 10.59 13 410939 61777 110116570
International normalised ratio increased 179.34 10.59 50 410902 86722 110091625
Gingival hypertrophy 178.96 10.59 140 410812 4191 110174156
Sleep disorder due to general medical condition, insomnia type 178.27 10.59 822 410130 104821 110073526
Nasal congestion 178.04 10.59 71 410881 98211 110080136
Graft versus host disease in lung 176.59 10.59 89 410863 1189 110177158
Rebound effect 175.99 10.59 245 410707 14561 110163786
Microsporidia infection 175.11 10.59 92 410860 1347 110177000
Sedation 173.25 10.59 26 410926 69657 110108690
Atypical mycobacterial infection 172.41 10.59 114 410838 2604 110175743
Enterobacter infection 172.12 10.59 155 410797 5656 110172691
Atypical haemolytic uraemic syndrome 172.03 10.59 93 410859 1447 110176900
Suicidal ideation 171.58 10.59 67 410885 93870 110084477
Neuropathy peripheral 171.38 10.59 250 410702 179027 109999320
Squamous cell carcinoma 169.93 10.59 271 410681 18192 110160155
Hyponatraemia 168.42 10.59 347 410605 217306 109961041
New onset diabetes after transplantation 167.70 10.59 62 410890 359 110177988
Pancreas transplant rejection 166.99 10.59 60 410892 316 110178031
Blood creatinine increased 165.64 10.59 1206 409746 181683 109996664
Hallucination 165.43 10.59 85 410867 101347 110077000
Pulmonary embolism 165.05 10.59 343 410609 214131 109964216
Drug reaction with eosinophilia and systemic symptoms 164.72 10.59 50 410902 82045 110096302
Injection site pruritus 163.77 10.59 6 410946 51252 110127095
Ureaplasma infection 163.39 10.59 90 410862 1456 110176891
Drug effective for unapproved indication 163.30 10.59 231 410721 13936 110164411
Graft complication 162.80 10.59 81 410871 1051 110177296
Epistaxis 162.29 10.59 147 410805 130225 110048122
Adenoviral hepatitis 162.27 10.59 78 410874 934 110177413
Swelling face 161.90 10.59 70 410882 92251 110086096
Angioedema 161.46 10.59 82 410870 98418 110079929
Peripheral swelling 160.47 10.59 864 410088 403170 109775177
Full blood count abnormal 159.28 10.59 13 410939 56039 110122308
Disseminated mycobacterium avium complex infection 158.69 10.59 63 410889 455 110177892
Infection in an immunocompromised host 155.19 10.59 94 410858 1833 110176514
Injection site bruising 154.06 10.59 9 410943 51254 110127093
Lip dry 153.81 10.59 758 410194 99325 110079022
Anogenital warts 153.72 10.59 78 410874 1058 110177289
Swollen tongue 153.62 10.59 21 410931 60341 110118006
Drug hypersensitivity 153.49 10.59 1022 409930 453068 109725279
Pneumonia fungal 153.23 10.59 229 410723 14525 110163822
Obliterative bronchiolitis 153.09 10.59 120 410832 3603 110174744
Pneumonia cryptococcal 152.54 10.59 103 410849 2439 110175908
Pneumonia klebsiella 151.02 10.59 153 410799 6479 110171868
Rheumatic fever 150.63 10.59 873 410079 121706 110056641
Gastroenteritis norovirus 149.80 10.59 117 410835 3494 110174853
Depression 147.84 10.59 641 410311 316694 109861653
Organising pneumonia 147.83 10.59 221 410731 14022 110164325
Multiple sclerosis relapse 147.46 10.59 10 410942 50230 110128117
Angiosarcoma 146.21 10.59 61 410891 508 110177839
Oropharyngeal pain 145.29 10.59 173 410779 135103 110043244
Emphysematous pyelonephritis 145.28 10.59 61 410891 517 110177830
Cardio-respiratory arrest 144.91 10.59 130 410822 115706 110062641
Visceral leishmaniasis 144.88 10.59 87 410865 1669 110176678
Systemic candida 144.72 10.59 182 410770 9792 110168555
Acinetobacter infection 144.41 10.59 114 410838 3459 110174888
Post transplant distal limb syndrome 144.38 10.59 69 410883 815 110177532
Idiopathic pneumonia syndrome 144.16 10.59 69 410883 818 110177529
Intentional product misuse 143.77 10.59 169 410783 132735 110045612
Agitation 143.68 10.59 125 410827 112926 110065421
Human herpesvirus 6 encephalitis 143.17 10.59 73 410879 1001 110177346
Cytomegalovirus enteritis 142.91 10.59 73 410879 1005 110177342
Encephalitis 142.10 10.59 253 410699 18586 110159761
Dermatophytosis 141.74 10.59 60 410892 520 110177827
Platelet count decreased 141.68 10.59 414 410538 230029 109948318
Monkeypox 141.51 10.59 53 410899 320 110178027
Pre-engraftment immune reaction 141.23 10.59 56 410896 403 110177944
Gastrooesophageal reflux disease 140.02 10.59 286 410666 179690 109998657
Vision blurred 139.64 10.59 164 410788 128858 110049489
Ureteric stenosis 139.27 10.59 82 410870 1515 110176832
Neck pain 139.27 10.59 151 410801 122979 110055368
Orthostatic hypotension 137.23 10.59 38 410914 66211 110112136
Blood pressure decreased 135.97 10.59 136 410816 114955 110063392
Human ehrlichiosis 135.96 10.59 62 410890 653 110177694
Rhodococcus infection 135.94 10.59 56 410896 450 110177897
Incorrect dose administered 134.89 10.59 112 410840 103529 110074818
Mycobacterium abscessus infection 134.26 10.59 82 410870 1624 110176723
Influenza like illness 134.20 10.59 81 410871 88331 110090016
Pancytopenia 134.01 10.59 1278 409674 208335 109970012
Immune reconstitution inflammatory syndrome 132.94 10.59 226 410726 16000 110162347
Cryptococcal cutaneous infection 132.03 10.59 48 410904 263 110178084
Transient ischaemic attack 131.98 10.59 37 410915 63945 110114402
Alveolar proteinosis 131.67 10.59 78 410874 1458 110176889
Trichophytosis 131.51 10.59 54 410898 430 110177917
Therapy partial responder 131.48 10.59 368 410584 36693 110141654
Hot flush 131.08 10.59 41 410911 65995 110112352
Rhinorrhoea 129.89 10.59 114 410838 102552 110075795
Cerebral fungal infection 129.69 10.59 60 410892 655 110177692
Illness 129.39 10.59 72 410880 82099 110096248
Malacoplakia gastrointestinal 128.99 10.59 45 410907 214 110178133
Pyelonephritis 128.86 10.59 288 410664 24962 110153385
Cytomegalovirus gastritis 128.75 10.59 59 410893 629 110177718
Norovirus infection 128.38 10.59 90 410862 2269 110176078
Hydronephrosis 126.68 10.59 254 410698 20411 110157936
Dysphonia 126.26 10.59 62 410890 75867 110102480
Nasopharyngitis 126.10 10.59 902 410050 393459 109784888
Disseminated mucormycosis 125.72 10.59 85 410867 2017 110176330
Intentional self-injury 124.60 10.59 3 410949 37426 110140921
Enterococcal bacteraemia 124.33 10.59 115 410837 4346 110174001
Cystitis viral 124.18 10.59 74 410878 1399 110176948
Anxiety 124.04 10.59 762 410190 344316 109834031
Haemoglobin decreased 122.91 10.59 491 410461 248236 109930111
Lactic acidosis 122.40 10.59 99 410853 92712 110085635
Dysgeusia 121.23 10.59 54 410898 69931 110108416
Psoriasis 119.84 10.59 210 410742 139783 110038564
Accidental exposure to product 119.08 10.59 21 410931 49987 110128360
Mycobacterium chelonae infection 118.05 10.59 95 410857 2965 110175382
Blood potassium decreased 117.92 10.59 28 410924 54086 110124261
Humoral immune defect 117.61 10.59 57 410895 696 110177651
American trypanosomiasis 117.49 10.59 54 410898 580 110177767
Human herpesvirus 6 infection reactivation 117.33 10.59 65 410887 1064 110177283
Unevaluable event 117.15 10.59 37 410915 59190 110119157
Cognitive disorder 117.10 10.59 92 410860 87419 110090928
Apoptosis 116.54 10.59 56 410896 670 110177677
Nightmare 116.25 10.59 7 410945 38856 110139491
Epstein-Barr virus test positive 115.41 10.59 68 410884 1258 110177089
Aggression 115.33 10.59 38 410914 59172 110119175
Respiratory arrest 114.29 10.59 37 410915 58262 110120085
Bronchitis 114.28 10.59 259 410693 156773 110021574
Muscle spasms 113.62 10.59 589 410363 277568 109900779
Serotonin syndrome 113.41 10.59 39 410913 59114 110119233
Neurotoxicity 113.18 10.59 380 410572 41827 110136520
Lip swelling 112.84 10.59 25 410927 50642 110127705
Haematochezia 112.46 10.59 159 410793 115365 110062982
Anti-erythropoietin antibody negative 112.34 10.59 43 410909 278 110178069
Infection 112.34 10.59 1931 409021 360269 109818078
Demodicidosis 112.06 10.59 40 410912 206 110178141
Cardiac disorder 111.48 10.59 73 410879 76207 110102140
Oxygen saturation decreased 110.96 10.59 263 410689 156719 110021628
Locked-in syndrome 110.57 10.59 59 410893 893 110177454
Liver disorder 110.41 10.59 905 410047 141338 110037009
Blood glucose increased 109.60 10.59 203 410749 132293 110046054
Endophthalmitis 108.75 10.59 143 410809 8044 110170303
Disseminated aspergillosis 108.65 10.59 83 410869 2397 110175950
Disseminated cytomegaloviral infection 108.64 10.59 51 410901 577 110177770
Anaphylactic reaction 108.62 10.59 160 410792 114140 110064207
Injection site haemorrhage 108.62 10.59 3 410949 33025 110145322
Bone pain 108.58 10.59 53 410899 65080 110113267
Diabetes mellitus 108.24 10.59 686 410266 98695 110079652
C-reactive protein abnormal 108.22 10.59 839 410113 128856 110049491
Chronic graft versus host disease in eye 107.32 10.59 45 410907 380 110177967
Therapeutic product effect incomplete 107.32 10.59 447 410505 223358 109954989
Mycetoma mycotic 107.01 10.59 45 410907 383 110177964
Enterocolitis viral 106.28 10.59 56 410896 825 110177522
Donor specific antibody present 105.92 10.59 44 410908 362 110177985
Drug level fluctuating 105.80 10.59 58 410894 929 110177418
Heart rate decreased 105.77 10.59 91 410861 82665 110095682
Eye infection toxoplasmal 105.23 10.59 53 410899 707 110177640
Drug withdrawal syndrome 104.94 10.59 10 410942 38044 110140303
Rhinovirus infection 104.34 10.59 170 410782 11619 110166728
Bronchiolitis obliterans syndrome 104.07 10.59 51 410901 639 110177708
Vertigo 103.36 10.59 102 410850 86768 110091579
Gait disturbance 103.29 10.59 608 410344 277600 109900747
Thrombosis 102.39 10.59 153 410799 108509 110069838
Glomerulosclerosis 102.09 10.59 62 410890 1215 110177132
Mediastinitis 101.50 10.59 64 410888 1344 110177003
Acute myocardial infarction 101.26 10.59 97 410855 83680 110094667
Graft versus host disease in eye 100.63 10.59 44 410908 416 110177931
Adjustment disorder with depressed mood 100.40 10.59 375 410577 43508 110134839
Rhabdomyolysis 100.01 10.59 184 410768 120217 110058130
Abdominal pain 99.74 10.59 1325 409627 511664 109666683
X-ray abnormal 99.41 10.59 340 410612 37777 110140570
Joint range of motion decreased 99.37 10.59 784 410168 121048 110057299
Tachycardia 98.82 10.59 469 410483 226176 109952171
Photodermatosis 97.73 10.59 57 410895 1034 110177313
Angiosarcoma metastatic 97.57 10.59 34 410918 161 110178186
Retinitis 97.50 10.59 303 410649 32024 110146323
Pyelonephritis acute 97.38 10.59 127 410825 7086 110171261
Cutaneous malacoplakia 96.87 10.59 33 410919 144 110178203
Glomerulonephritis membranoproliferative 96.82 10.59 52 410900 798 110177549
Central nervous system viral infection 96.70 10.59 39 410913 295 110178052
Central nervous system infection 96.41 10.59 67 410885 1665 110176682
Lupus vulgaris 96.17 10.59 311 410641 33572 110144775
Citrobacter infection 95.91 10.59 61 410891 1301 110177046
Hypothyroidism 95.83 10.59 78 410874 72821 110105526
Herpes zoster meningoencephalitis 95.71 10.59 56 410896 1022 110177325
Periostitis 95.57 10.59 51 410901 772 110177575
Skin exfoliation 95.28 10.59 111 410841 87540 110090807
Chronic graft versus host disease in intestine 95.19 10.59 48 410904 642 110177705
Depressed level of consciousness 94.67 10.59 170 410782 112108 110066239
Mycobacterium avium complex infection 94.59 10.59 113 410839 5764 110172583
Reversible cerebral vasoconstriction syndrome 94.39 10.59 102 410850 4659 110173688
Device dislocation 93.96 10.59 6 410946 31698 110146649
Heart rate increased 93.87 10.59 251 410701 143583 110034764
Urinary tract infection bacterial 93.66 10.59 132 410820 7935 110170412
Aspartate aminotransferase increased 93.50 10.59 294 410658 159642 110018705
Choroiditis 93.49 10.59 64 410888 1551 110176796
Steroid diabetes 92.86 10.59 106 410846 5148 110173199
Tubulointerstitial nephritis 92.75 10.59 424 410528 53860 110124487
Joint injury 92.64 10.59 18 410934 39976 110138371
Endocarditis 92.53 10.59 173 410779 13198 110165149
Rash pruritic 92.48 10.59 138 410814 97931 110080416
Confusional state 92.39 10.59 1207 409745 467473 109710874
Flatulence 92.29 10.59 39 410913 52110 110126237
Head injury 92.28 10.59 23 410929 42994 110135353
Eye pruritus 92.03 10.59 8 410944 32767 110145580
Restlessness 91.95 10.59 47 410905 56212 110122135
Rash erythematous 91.82 10.59 101 410851 81731 110096616
Varicella 91.73 10.59 90 410862 3665 110174682
Pneumonia pseudomonal 91.38 10.59 126 410826 7420 110170927
Central nervous system fungal infection 90.98 10.59 45 410907 576 110177771
Presyncope 90.71 10.59 34 410918 48853 110129494
Cushingoid 90.55 10.59 159 410793 11553 110166794
Product quality issue 90.55 10.59 92 410860 77207 110101140
Coccidioidomycosis 90.36 10.59 63 410889 1574 110176773
Neoplasm progression 90.16 10.59 65 410887 64530 110113817
Polyomavirus test positive 88.97 10.59 35 410917 246 110178101
Kaposi's sarcoma 88.62 10.59 46 410906 656 110177691
Tinnitus 88.38 10.59 58 410894 60482 110117865
Eczema 88.20 10.59 83 410869 72210 110106137
Fibromyalgia 87.87 10.59 997 409955 169912 110008435
Skin squamous cell carcinoma metastatic 87.79 10.59 27 410925 78 110178269
Corynebacterium infection 87.76 10.59 67 410885 1933 110176414
Prescribed overdose 87.73 10.59 592 410360 86989 110091358
Blood calcium decreased 87.68 10.59 14 410938 35831 110142516
Paraesthesia 87.59 10.59 634 410318 275887 109902460
Anaphylactic shock 87.37 10.59 41 410911 51505 110126842
Superinfection bacterial 87.27 10.59 72 410880 2329 110176018
Throat irritation 87.13 10.59 45 410907 53507 110124840
Necrotising retinitis 87.11 10.59 61 410891 1535 110176812
Cutaneous mucormycosis 86.93 10.59 46 410906 684 110177663
Loss of personal independence in daily activities 86.84 10.59 277 410675 149743 110028604
Renal tubular acidosis 86.53 10.59 97 410855 4618 110173729
Pneumomediastinum 86.31 10.59 100 410852 4936 110173411
Gastroenteritis cryptosporidial 86.30 10.59 37 410915 332 110178015
Feeling cold 86.07 10.59 12 410940 33975 110144372
Rheumatoid factor positive 85.78 10.59 806 410146 130834 110047513
Pneumoperitoneum 85.45 10.59 89 410863 3895 110174452
Unresponsive to stimuli 85.42 10.59 67 410885 63723 110114624
Toxic skin eruption 85.29 10.59 4 410948 27511 110150836
Microangiopathic haemolytic anaemia 85.06 10.59 65 410887 1878 110176469
Opportunistic infection 84.84 10.59 84 410868 3459 110174888
Influenza 84.67 10.59 332 410620 168769 110009578
Nervousness 84.49 10.59 17 410935 36834 110141513
Glomerulonephritis proliferative 84.33 10.59 40 410912 464 110177883
Fusarium infection 84.22 10.59 75 410877 2696 110175651
Acute kidney injury 84.15 10.59 3017 407935 632413 109545934
Complications of transplant surgery 84.12 10.59 46 410906 733 110177614
Herpes virus infection 83.94 10.59 130 410822 8508 110169839
Facet joint syndrome 83.91 10.59 632 410320 96196 110082151
Encephalitis cytomegalovirus 83.85 10.59 64 410888 1846 110176501
Skin papilloma 83.29 10.59 115 410837 6781 110171566
Tuberculosis 83.26 10.59 196 410756 17578 110160769
Dysarthria 82.65 10.59 115 410837 84006 110094341
Staphylococcal bacteraemia 82.54 10.59 188 410764 16500 110161847
Therapy interrupted 82.36 10.59 41 410911 49781 110128566
Chronic graft versus host disease oral 82.25 10.59 39 410913 452 110177895
Insomnia 82.00 10.59 900 410052 359690 109818657
Cholelithiasis 81.96 10.59 69 410883 63353 110114994
Gastrointestinal disorder 81.62 10.59 1308 409644 240644 109937703
Coronary artery disease 80.97 10.59 88 410864 71602 110106745
Cytomegalovirus syndrome 80.89 10.59 34 410918 289 110178058
Herpes simplex hepatitis 80.83 10.59 45 410907 744 110177603
Nephrolithiasis 80.80 10.59 76 410876 66136 110112211
Gastrointestinal mucormycosis 80.69 10.59 44 410908 697 110177650
Lacrimation increased 80.60 10.59 10 410942 30940 110147407
Haematemesis 80.53 10.59 61 410891 59047 110119300
Urinary retention 80.41 10.59 84 410868 69599 110108748
Autoimmune haemolytic anaemia 79.81 10.59 142 410810 10425 110167922
Hypersensitivity 79.75 10.59 1040 409912 402958 109775389
Neuroleptic malignant syndrome 79.59 10.59 15 410937 34044 110144303
Lethargy 79.51 10.59 141 410811 93435 110084912
Hospitalisation 79.09 10.59 268 410684 142225 110036122
Venoocclusive disease 78.36 10.59 107 410845 6243 110172104
Device malfunction 78.32 10.59 4 410948 25554 110152793
SARS-CoV-2 RNA increased 78.29 10.59 29 410923 169 110178178
Peritonitis 78.26 10.59 283 410669 32324 110146023
Burning sensation 78.12 10.59 85 410867 69127 110109220
Adenovirus reactivation 77.99 10.59 43 410909 697 110177650
Gastroenteritis sapovirus 77.86 10.59 30 410922 198 110178149
Angina pectoris 77.80 10.59 70 410882 62225 110116122
Herpes simplex pneumonia 77.64 10.59 35 410917 358 110177989
Femur fracture 77.51 10.59 34 410918 44435 110133912
Transitional cell carcinoma 77.37 10.59 76 410876 3099 110175248
Sinus disorder 77.37 10.59 14 410938 32714 110145633
Dysphagia 77.26 10.59 301 410651 153299 110025048
Respiratory depression 77.16 10.59 13 410939 31988 110146359
Disseminated strongyloidiasis 77.15 10.59 40 410912 569 110177778
Sneezing 77.10 10.59 13 410939 31971 110146376
Meningoencephalitis herpetic 76.98 10.59 67 410885 2335 110176012
Stevens-Johnson syndrome 76.92 10.59 39 410913 46862 110131485
Ocular hyperaemia 76.89 10.59 25 410927 39261 110139086
Enterovirus infection 76.41 10.59 71 410881 2699 110175648
Paraesthesia oral 76.23 10.59 16 410936 33655 110144692
Chest pain 76.10 10.59 964 409988 375411 109802936
Pallor 76.00 10.59 59 410893 56408 110121939
Orf 75.89 10.59 22 410930 48 110178299
Drug interaction 75.86 10.59 2413 408539 497770 109680577
Mucosal inflammation 75.84 10.59 614 410338 95527 110082820
Osteonecrosis of jaw 75.70 10.59 42 410910 47975 110130372
Legionella infection 75.36 10.59 46 410906 910 110177437
Full blood count decreased 75.30 10.59 14 410938 32085 110146262
Urinary tract infection viral 75.25 10.59 24 410928 81 110178266
Injection site mass 74.95 10.59 4 410948 24609 110153738
Productive cough 74.94 10.59 199 410753 114106 110064241
Perinephric abscess 74.87 10.59 35 410917 392 110177955
Metastatic squamous cell carcinoma 74.67 10.59 42 410910 709 110177638
Finger deformity 74.36 10.59 16 410936 33076 110145271
Heart rate irregular 74.16 10.59 18 410934 34256 110144091
Blood creatine phosphokinase increased 73.71 10.59 98 410854 72979 110105368
Therapeutic product effect decreased 73.64 10.59 568 410384 243748 109934599
Renal vein thrombosis 73.34 10.59 48 410904 1077 110177270
Acute myeloid leukaemia recurrent 73.33 10.59 93 410859 5046 110173301
Biliary anastomosis complication 73.22 10.59 27 410925 155 110178192
Apoptotic colonopathy 73.16 10.59 28 410924 181 110178166
Fungal endocarditis 73.10 10.59 43 410909 793 110177554
Haemodialysis 73.02 10.59 186 410766 17533 110160814
Withdrawal syndrome 72.95 10.59 14 410938 31366 110146981
Fungaemia 72.77 10.59 101 410851 5985 110172362
Folliculitis 72.69 10.59 947 410005 166706 110011641
Choriomeningitis lymphocytic 72.65 10.59 27 410925 159 110178188
Accidental overdose 72.55 10.59 52 410900 51782 110126565
Skin laceration 72.50 10.59 18 410934 33735 110144612
Cytomegalovirus hepatitis 72.46 10.59 44 410908 862 110177485
Engraftment syndrome 72.46 10.59 59 410893 1873 110176474
Disturbance in attention 72.37 10.59 74 410878 61921 110116426
Pulmonary tuberculosis 71.86 10.59 125 410827 9014 110169333
Complications of transplanted liver 71.76 10.59 36 410916 476 110177871
Cutaneous T-cell lymphoma 71.51 10.59 75 410877 3309 110175038
Graft thrombosis 71.36 10.59 36 410916 482 110177865
Drug eruption 71.04 10.59 57 410895 53602 110124745
Type 2 diabetes mellitus 71.03 10.59 987 409965 176245 110002102
Engraft failure 70.95 10.59 42 410910 784 110177563
Cutaneous blastomycosis 70.92 10.59 22 410930 66 110178281
Renal transplant 70.65 10.59 73 410879 3165 110175182
Pulmonary fibrosis 70.64 10.59 633 410319 101409 110076938
Cytomegalovirus gastroenteritis 70.56 10.59 40 410912 686 110177661
Depressed mood 70.51 10.59 73 410879 60736 110117611
Parvovirus infection 70.49 10.59 44 410908 907 110177440
Liver abscess 70.40 10.59 113 410839 7626 110170721
C3 glomerulopathy 70.26 10.59 26 410926 151 110178196
Product prescribing error 69.90 10.59 53 410899 51278 110127069
Febrile neutropenia 69.88 10.59 796 410156 315971 109862376
Erythema infectiosum 69.86 10.59 28 410924 208 110178139
Urinary tract infection enterococcal 69.38 10.59 77 410875 3625 110174722
Toxic epidermal necrolysis 69.35 10.59 65 410887 56662 110121685
Malignant fibrous histiocytoma 69.05 10.59 29 410923 246 110178101
Procedural pain 68.96 10.59 23 410929 35542 110142805
Dyskinesia 68.93 10.59 54 410898 51392 110126955
Gastroenteritis rotavirus 68.71 10.59 37 410915 571 110177776
Hypocalcaemia 68.68 10.59 85 410867 65281 110113066
Oedema peripheral 68.60 10.59 836 410116 327824 109850523
Skin graft rejection 68.59 10.59 22 410930 76 110178271
Necrosis 68.48 10.59 139 410813 11267 110167080
Pneumonia necrotising 68.25 10.59 55 410897 1720 110176627
Dengue fever 68.05 10.59 49 410903 1290 110177057
Red blood cell count decreased 67.94 10.59 87 410865 65836 110112511
Necrotising herpetic retinopathy 67.81 10.59 26 410926 169 110178178
Inferior vena cava stenosis 67.77 10.59 23 410929 99 110178248
Joint swelling 67.54 10.59 1198 409754 441647 109736700
Cytomegalovirus nephritis 67.44 10.59 25 410927 146 110178201
Cerebral aspergillosis 67.39 10.59 61 410891 2241 110176106
Blood iron abnormal 67.36 10.59 51 410901 1453 110176894
Herpes zoster 66.86 10.59 656 410296 107723 110070624
Candida sepsis 66.86 10.59 68 410884 2893 110175454
Hypertrophic cardiomyopathy 66.66 10.59 70 410882 3093 110175254
Skin discolouration 66.32 10.59 51 410901 48995 110129352
Contraindicated product administered 65.86 10.59 597 410355 247670 109930677
Infectious pleural effusion 65.85 10.59 86 410866 4805 110173542
Blood test abnormal 65.82 10.59 13 410939 28541 110149806
Sleep apnoea syndrome 65.79 10.59 34 410918 40413 110137934
Miosis 65.63 10.59 4 410948 21979 110156368
Dystonia 65.61 10.59 9 410943 25796 110152551
Renal artery stenosis 65.56 10.59 75 410877 3651 110174696
BK polyomavirus test positive 65.52 10.59 29 410923 283 110178064
Cryptococcal meningoencephalitis 65.40 10.59 31 410921 359 110177988
Arteritis infective 65.40 10.59 25 410927 161 110178186
Retinal vasculitis 65.36 10.59 57 410895 1992 110176355
Pericarditis fungal 65.35 10.59 29 410923 285 110178062
Bacterial infection 65.33 10.59 341 410611 45695 110132652
Urinary incontinence 65.10 10.59 51 410901 48536 110129811
Post procedural bile leak 65.08 10.59 32 410920 404 110177943
Obstructive airways disorder 64.98 10.59 46 410906 46103 110132244
Psoriatic arthropathy 64.59 10.59 1059 409893 195702 109982645
Solar lentigo 64.57 10.59 50 410902 1474 110176873
Vasogenic cerebral oedema 64.47 10.59 59 410893 2199 110176148
Passenger lymphocyte syndrome 64.38 10.59 25 410927 169 110178178
SLE arthritis 64.36 10.59 36 410916 601 110177746
Blood sodium decreased 64.15 10.59 31 410921 38288 110140059
Wound dehiscence 64.04 10.59 110 410842 7852 110170495
Chronic inflammatory demyelinating polyradiculoneuropathy 63.93 10.59 58 410894 2137 110176210
Chromoblastomycosis 63.93 10.59 24 410928 146 110178201
Chronic kidney disease 63.89 10.59 494 410458 75797 110102550
Alanine aminotransferase increased 63.81 10.59 410 410542 183363 109994984
Dermoid cyst 63.74 10.59 33 410919 468 110177879
Abscess fungal 63.72 10.59 32 410920 424 110177923
Troponin increased 63.69 10.59 16 410936 29750 110148597
Serum sickness 63.29 10.59 80 410872 4326 110174021
Growth retardation 63.29 10.59 62 410890 2520 110175827
Back injury 63.19 10.59 50 410902 47349 110130998
Prescribed underdose 63.16 10.59 437 410515 64737 110113610
Oropharyngeal squamous cell carcinoma 62.81 10.59 29 410923 315 110178032
Arthritis bacterial 62.77 10.59 130 410822 10690 110167657
Tuberculosis gastrointestinal 62.74 10.59 35 410917 581 110177766
Duodenal ulcer perforation 62.70 10.59 968 409984 176732 110001615
Limb discomfort 62.60 10.59 37 410915 40817 110137530
Colitis 62.47 10.59 618 410334 101705 110076642
Disseminated toxoplasmosis 62.36 10.59 32 410920 445 110177902
Dislocation of vertebra 62.15 10.59 324 410628 43397 110134950
Proteus infection 62.14 10.59 64 410888 2764 110175583
Fluid retention 61.96 10.59 164 410788 94143 110084204
Lymphocytic infiltration 61.93 10.59 55 410897 1970 110176377
Renal phospholipidosis 61.78 10.59 30 410922 368 110177979
Restless legs syndrome 61.65 10.59 9 410943 24617 110153730
Klebsiella bacteraemia 61.53 10.59 83 410869 4786 110173561
Tremor 61.48 10.59 469 410483 201763 109976584
Skin squamous cell carcinoma recurrent 61.40 10.59 21 410931 93 110178254
B-lymphocyte count decreased 61.23 10.59 55 410897 2000 110176347
Pleocytosis 61.21 10.59 51 410901 1673 110176674
Splenic abscess 61.16 10.59 41 410911 959 110177388
Serositis 61.14 10.59 49 410903 1520 110176827
Biopsy lung abnormal 60.98 10.59 23 410929 142 110178205
Blood glucose decreased 60.91 10.59 17 410935 29471 110148876
Speech disorder 60.65 10.59 84 410868 61485 110116862
Irritability 60.57 10.59 53 410899 47756 110130591
Enterococcal sepsis 60.54 10.59 68 410884 3244 110175103
Crying 60.50 10.59 11 410941 25617 110152730
Sinus congestion 60.29 10.59 19 410933 30440 110147907
Dry eye 60.27 10.59 71 410881 55722 110122625
Product dose omission in error 60.25 10.59 8 410944 23504 110154843
Cold sweat 60.20 10.59 6 410946 22025 110156322
Disseminated trichosporonosis 60.15 10.59 25 410927 206 110178141
Anaemia 60.14 10.59 1560 409392 545526 109632821
Muir-Torre syndrome 60.12 10.59 18 410934 46 110178301
Deep vein thrombosis 60.06 10.59 291 410661 139596 110038751
Skin lesion 59.72 10.59 362 410590 51269 110127078
Pollakiuria 59.71 10.59 46 410906 44149 110134198
Haemodynamic instability 59.54 10.59 204 410748 22684 110155663
Pneumonia influenzal 59.34 10.59 72 410880 3733 110174614
Vesicoureteric reflux 58.90 10.59 24 410928 187 110178160
Chronic myeloid leukaemia 58.88 10.59 76 410876 4197 110174150
Escherichia urinary tract infection 58.82 10.59 162 410790 16000 110162347
Listeriosis 58.81 10.59 62 410890 2752 110175595
Taste disorder 58.79 10.59 95 410857 65292 110113055
Encephalitis autoimmune 58.70 10.59 69 410883 3459 110174888
Babesiosis 58.40 10.59 31 410921 464 110177883
Agranulocytosis 58.03 10.59 411 410541 61349 110116998
Hip fracture 57.99 10.59 29 410923 35122 110143225
Body tinea 57.94 10.59 54 410898 2061 110176286
Sputum discoloured 57.93 10.59 16 410936 27929 110150418
Rash macular 57.93 10.59 36 410916 38650 110139697
Renal cell carcinoma 57.92 10.59 102 410850 7428 110170919
Skin haemorrhage 57.87 10.59 11 410941 24816 110153531
Varicella zoster pneumonia 57.70 10.59 29 410923 385 110177962
Eye irritation 57.64 10.59 26 410926 33426 110144921
Neuralgia 57.57 10.59 57 410895 48421 110129926
Prostatic abscess 57.50 10.59 33 410919 580 110177767
Nodular regenerative hyperplasia 57.39 10.59 48 410904 1583 110176764
Respiratory tract infection fungal 57.32 10.59 44 410908 1280 110177067
Graft infection 57.26 10.59 36 410916 752 110177595
Osteomyelitis fungal 56.98 10.59 29 410923 396 110177951
Neuroendocrine carcinoma of the skin 56.59 10.59 49 410903 1696 110176651
Maternal exposure timing unspecified 56.17 10.59 189 410763 20824 110157523
Pneumonia acinetobacter 56.16 10.59 28 410924 365 110177982
Nephropathy 56.15 10.59 142 410810 13325 110165022
Tuberculosis of central nervous system 56.03 10.59 31 410921 506 110177841
Bile duct stenosis 56 10.59 59 410893 2617 110175730
Hepatic artery thrombosis 55.96 10.59 28 410924 368 110177979
Muscle spasticity 55.78 10.59 32 410920 35883 110142464
Tularaemia 55.71 10.59 23 410929 186 110178161
Porphyria acute 55.69 10.59 175 410777 18605 110159742
Enteritis 55.42 10.59 177 410775 18979 110159368
Pain in jaw 55.41 10.59 65 410887 51112 110127235
Mycobacterium fortuitum infection 55.31 10.59 30 410922 470 110177877
Wound infection 55.23 10.59 575 410377 95890 110082457
Decreased appetite 55.21 10.59 1346 409606 474500 109703847
Granuloma 55.03 10.59 114 410838 9376 110168971
Glomerulonephropathy 54.98 10.59 27 410925 340 110178007
Cardiac arrest 54.88 10.59 467 410485 196286 109982061
Respiratory tract congestion 54.73 10.59 23 410929 30834 110147513
Fear 54.65 10.59 10 410942 23183 110155164
Skin fissures 54.60 10.59 12 410940 24446 110153901
Oliguria 54.54 10.59 173 410779 18484 110159863
Hepatitis B reactivation 54.52 10.59 99 410853 7385 110170962
Reticulocytopenia 54.41 10.59 26 410926 307 110178040
Cardiac failure 54.30 10.59 441 410511 187185 109991162
Cutaneous tuberculosis 54.11 10.59 25 410927 272 110178075
Hepatitis B 54.03 10.59 114 410838 9498 110168849
Fungal abscess central nervous system 53.87 10.59 23 410929 204 110178143
Product administration error 53.86 10.59 36 410916 37181 110141166
Acute disseminated encephalomyelitis 53.78 10.59 28 410924 402 110177945
Breath sounds abnormal 53.69 10.59 14 410938 25390 110152957
Liver injury 53.68 10.59 821 410131 149592 110028755
Melaena 53.67 10.59 109 410843 68648 110109699
Fungal sepsis 53.50 10.59 53 410899 2184 110176163
Oesophageal stenosis 53.40 10.59 80 410872 5085 110173262
Helicobacter infection 53.22 10.59 961 409991 180916 109997431
Nephrectomy 53.11 10.59 57 410895 2583 110175764
Viral vasculitis 53.11 10.59 23 410929 212 110178135
Guillain-Barre syndrome 53.10 10.59 121 410831 10623 110167724
Retching 52.98 10.59 10 410942 22672 110155675
Urine protein/creatinine ratio increased 52.69 10.59 45 410907 1528 110176819
Disseminated intravascular coagulation 52.63 10.59 297 410655 40989 110137358
Salivary hypersecretion 52.53 10.59 3 410949 17418 110160929
Dysplastic naevus 52.42 10.59 35 410917 813 110177534
Skin mass 52.39 10.59 114 410838 9702 110168645
Sinus bradycardia 52.25 10.59 22 410930 29461 110148886
Glucose tolerance impaired 52.23 10.59 114 410838 9723 110168624
Erythema multiforme 52.14 10.59 8 410944 21089 110157258
Gallbladder disorder 51.92 10.59 8 410944 21021 110157326
Oesophagitis ulcerative 51.91 10.59 45 410907 1560 110176787
Rheumatoid nodule 51.79 10.59 7 410945 20289 110158058
Body temperature decreased 51.76 10.59 37 410915 36898 110141449
Bone marrow transplant rejection 51.67 10.59 25 410927 304 110178043
Overlap syndrome 51.57 10.59 108 410844 8951 110169396
Hiatus hernia 51.55 10.59 19 410933 27587 110150760
Product prescribing issue 51.52 10.59 133 410819 12639 110165708
Cytomegalovirus duodenitis 51.40 10.59 20 410932 136 110178211
Epstein-Barr virus antibody positive 51.34 10.59 32 410920 658 110177689
Propionibacterium infection 51.09 10.59 24 410928 272 110178075
Dyspnoea exertional 51.00 10.59 206 410746 103854 110074493
Cytomegalovirus enterocolitis 50.81 10.59 52 410900 2229 110176118
Upper gastrointestinal haemorrhage 50.71 10.59 67 410885 50029 110128318
Infective aneurysm 50.63 10.59 43 410909 1449 110176898
Burkholderia cepacia complex infection 50.40 10.59 28 410924 461 110177886
Musculoskeletal chest pain 50.37 10.59 22 410930 28825 110149522
Disseminated varicella zoster vaccine virus infection 50.19 10.59 20 410932 146 110178201
Middle insomnia 50.16 10.59 8 410944 20494 110157853
B-cell lymphoma 50.05 10.59 93 410859 7061 110171286
Renal tubular disorder 50.02 10.59 95 410857 7334 110171013
Orchitis 49.97 10.59 47 410905 1815 110176532
Meningitis bacterial 49.94 10.59 60 410892 3079 110175268
Product storage error 49.86 10.59 10 410942 21718 110156629
Sinus tachycardia 49.82 10.59 55 410897 44438 110133909
Rib fracture 49.77 10.59 32 410920 33738 110144609
Musculoskeletal discomfort 49.69 10.59 13 410939 23525 110154822
Localised infection 49.55 10.59 52 410900 42996 110135351
Superinfection viral 49.51 10.59 16 410936 57 110178290
Lung abscess 49.50 10.59 76 410876 4936 110173411
Dementia 49.50 10.59 28 410924 31645 110146702
Cutaneous nocardiosis 49.45 10.59 24 410928 294 110178053
Oxalosis 49.36 10.59 19 410933 125 110178222
Eye swelling 49.14 10.59 31 410921 33017 110145330
Abdominal discomfort 49.04 10.59 1102 409850 392756 109785591
Injection site urticaria 48.89 10.59 4 410948 17211 110161136
Clostridium difficile colitis 48.78 10.59 304 410648 43474 110134873
Osteoporosis 48.72 10.59 517 410435 86635 110091712
Adenoviral haemorrhagic cystitis 48.67 10.59 31 410921 663 110177684
Intestinal tuberculosis 48.63 10.59 23 410929 265 110178082
Respiratory syncytial virus infection 48.62 10.59 141 410811 14343 110164004
Escherichia bacteraemia 48.61 10.59 113 410839 10051 110168296
Grip strength 48.60 10.59 106 410846 9035 110169312
Bronchial polyp 48.53 10.59 17 410935 82 110178265
Abdominal infection 48.51 10.59 73 410879 4658 110173689
Breast cancer 48.50 10.59 43 410909 38499 110139848
Pneumonia adenoviral 48.42 10.59 30 410922 610 110177737
Onychomadesis 48.37 10.59 59 410893 45604 110132743
Cyanosis 48.37 10.59 25 410927 29716 110148631
Dysplasia 48.36 10.59 46 410906 1802 110176545
Seizure 48.29 10.59 557 410395 220628 109957719
Hypersomnia 48.05 10.59 22 410930 28039 110150308
Ankle fracture 47.89 10.59 8 410944 19811 110158536
Escherichia sepsis 47.82 10.59 113 410839 10159 110168188
Hepatic steatosis 47.72 10.59 67 410885 48764 110129583
Coeliac disease 47.68 10.59 54 410898 43133 110135214
Device leakage 47.67 10.59 3 410949 16045 110162302
Throat tightness 47.65 10.59 33 410919 33456 110144891
Spinal stenosis 47.62 10.59 7 410945 19049 110159298
Gastroenteritis adenovirus 47.62 10.59 26 410926 413 110177934
Cytopenia 47.61 10.59 230 410722 29886 110148461
Seasonal allergy 47.57 10.59 8 410944 19714 110158633
Lymphadenitis bacterial 47.56 10.59 17 410935 88 110178259
Liver function test increased 47.47 10.59 169 410783 88379 110089968
Mydriasis 47.23 10.59 12 410940 22145 110156202
Myopathy 47.22 10.59 201 410751 24759 110153588
Acute allograft nephropathy 47.17 10.59 15 410937 50 110178297
Upper limb fracture 47.13 10.59 10 410942 20878 110157469
Impaired healing 46.65 10.59 1007 409945 195710 109982637
Blood urine present 46.45 10.59 16 410936 24229 110154118
Normocytic anaemia 46.42 10.59 85 410867 6382 110171965
Pasteurella infection 46.41 10.59 19 410933 150 110178197
Necrotising fasciitis 46.16 10.59 93 410859 7498 110170849
Necrotising oesophagitis 46.06 10.59 42 410910 1558 110176789
Coordination abnormal 46.05 10.59 18 410934 25210 110153137
Multifocal micronodular pneumocyte hyperplasia 46.05 10.59 16 410936 75 110178272
Microangiopathy 45.96 10.59 56 410896 2916 110175431
Renal cortical necrosis 45.94 10.59 27 410925 497 110177850
Eosinophil count increased 45.68 10.59 11 410941 21047 110157300
Atypical mycobacterial pneumonia 45.52 10.59 23 410929 309 110178038
Abdominal pain upper 45.41 10.59 970 409982 348141 109830206
Klebsiella sepsis 45.35 10.59 66 410886 4087 110174260
Haemophilus infection 45.33 10.59 54 410898 2746 110175601
Lymphocyte count decreased 45.32 10.59 90 410862 57153 110121194
Shock haemorrhagic 45.19 10.59 211 410741 27036 110151311
Uveitis 45.14 10.59 180 410772 21530 110156817
Rash maculo-papular 45.10 10.59 134 410818 74088 110104259
Dysstasia 44.99 10.59 34 410918 32952 110145395
Lung infiltration 44.80 10.59 196 410756 24432 110153915
Aspergilloma 44.69 10.59 31 410921 768 110177579
Irritable bowel syndrome 44.69 10.59 858 410094 163357 110014990
Panic attack 44.64 10.59 26 410926 28914 110149433
Eating disorder 44.45 10.59 30 410922 30828 110147519
Toothache 44.41 10.59 16 410936 23559 110154788
Skin burning sensation 44.31 10.59 13 410939 21812 110156535
Pancreatitis necrotising 44.25 10.59 76 410876 5425 110172922
Multiple sclerosis 44.24 10.59 20 410932 25678 110152669
Diarrhoea 44.11 10.59 3641 407311 1135864 109042483
Chronic sinusitis 44.00 10.59 19 410933 25065 110153282
Female genital tract fistula 43.85 10.59 5 410947 16514 110161833
Acute generalised exanthematous pustulosis 43.81 10.59 13 410939 21651 110156696
Lung transplant 43.80 10.59 74 410878 5212 110173135
Peripheral artery aneurysm 43.75 10.59 26 410926 489 110177858
Eosinophilia 43.41 10.59 94 410858 57842 110120505
Disorientation 43.37 10.59 127 410825 70544 110107803
Immunosuppression 43.35 10.59 155 410797 17604 110160743
Histoplasmosis cutaneous 43.22 10.59 15 410937 70 110178277
Skin irritation 43.17 10.59 5 410947 16314 110162033
Haemolytic anaemia 43.14 10.59 173 410779 20747 110157600
Bordetella infection 43.10 10.59 20 410932 220 110178127
Anger 43.09 10.59 9 410943 18998 110159349
Oesophageal ulcer 43.09 10.59 93 410859 7871 110170476
Parainfluenzae virus infection 43.08 10.59 86 410866 6888 110171459
Central nervous system vasculitis 42.95 10.59 41 410911 1613 110176734
Hypothermia 42.94 10.59 22 410930 26280 110152067
Benign prostatic hyperplasia 42.67 10.59 8 410944 18226 110160121
Renal and pancreas transplant rejection 42.66 10.59 14 410938 53 110178294
Bone erosion 42.64 10.59 307 410645 46064 110132283
Weight decreased 42.49 10.59 1370 409582 466687 109711660
Odynophagia 42.36 10.59 132 410820 13969 110164378
Transplant abscess 42.26 10.59 14 410938 55 110178292
Cytomegalovirus urinary tract infection 42.26 10.59 16 410936 100 110178247
Thirst 42.15 10.59 14 410938 21693 110156654
Inflammatory bowel disease 42.06 10.59 87 410865 7147 110171200
Campylobacter infection 42.05 10.59 48 410904 2331 110176016
Macular degeneration 42.00 10.59 14 410938 21645 110156702
Endocarditis bacterial 41.76 10.59 42 410910 1763 110176584
Encapsulating peritoneal sclerosis 41.74 10.59 31 410921 857 110177490
Onychomycosis 41.65 10.59 49 410903 38482 110139865
Viral load increased 41.65 10.59 57 410895 3333 110175014
Limb injury 41.62 10.59 47 410905 37589 110140758
Subcapsular renal haematoma 41.60 10.59 32 410920 934 110177413
Cytomegalovirus mucocutaneous ulcer 41.55 10.59 17 410935 134 110178213
Emotional distress 41.42 10.59 64 410888 44783 110133564
Acid fast bacilli infection 41.26 10.59 19 410933 205 110178142
Hepatic fibrosis 41.15 10.59 92 410860 7974 110170373
Trichosporon infection 41.14 10.59 36 410916 1264 110177083
Hepatitis viral 41.06 10.59 38 410914 1437 110176910
Infusion related reaction 41.02 10.59 1090 409862 380072 109798275
Arthritis 41.01 10.59 411 410541 167175 110011172
Myelitis 40.95 10.59 55 410897 3158 110175189
Rectal haemorrhage 40.75 10.59 269 410683 119564 110058783
Calciphylaxis 40.67 10.59 63 410889 4124 110174223
Arthropathy 40.62 10.59 788 410164 286734 109891613
Alpha haemolytic streptococcal infection 40.55 10.59 58 410894 3535 110174812
Product complaint 40.37 10.59 3 410949 13969 110164378
Viral diarrhoea 40.33 10.59 26 410926 568 110177779
Injury 40.31 10.59 902 410050 176363 110001984
Angiocentric lymphoma 40.16 10.59 35 410917 1222 110177125
Hyperplasia 40.13 10.59 38 410914 1480 110176867
Ureteral necrosis 40.13 10.59 15 410937 90 110178257
Hypoacusis 39.95 10.59 43 410909 35148 110143199
Carpal tunnel syndrome 39.86 10.59 17 410935 22593 110155754
Vascular graft complication 39.86 10.59 18 410934 185 110178162
Meningoencephalitis viral 39.86 10.59 25 410927 520 110177827
Cytokine release syndrome 39.85 10.59 131 410821 70175 110108172
Empyema 39.71 10.59 73 410879 5497 110172850
Infection susceptibility increased 39.71 10.59 64 410888 4334 110174013
Hypertrophic osteoarthropathy 39.67 10.59 16 410936 121 110178226
Cardiac infection 39.67 10.59 27 410925 648 110177699
Device breakage 39.66 10.59 3 410949 13766 110164581
Rhinitis allergic 39.59 10.59 9 410943 17913 110160434
Vaginal discharge 39.54 10.59 9 410943 17899 110160448
Muscle twitching 39.38 10.59 32 410920 29903 110148444
Meningitis fungal 39.35 10.59 21 410931 318 110178029
Prophylaxis against transplant rejection 39.32 10.59 15 410937 96 110178251
Bacterial pyelonephritis 39.23 10.59 29 410923 796 110177551
Wrist fracture 39.20 10.59 4 410948 14413 110163934
Activated partial thromboplastin time prolonged 39.15 10.59 17 410935 22351 110155996
Tardive dyskinesia 39.00 10.59 3 410949 13576 110164771
Scrotal ulcer 38.96 10.59 23 410929 427 110177920
Bronchospasm 38.94 10.59 33 410919 30206 110148141
Angina unstable 38.90 10.59 7 410945 16425 110161922
Disseminated coccidioidomycosis 38.85 10.59 19 410933 237 110178110
Hyperthyroidism 38.84 10.59 31 410921 29230 110149117
Muscle injury 38.75 10.59 737 410215 140070 110038277
Drug level decreased 38.74 10.59 154 410798 18394 110159953
Pulmonary alveolar haemorrhage 38.68 10.59 163 410789 19987 110158360
Hepatic necrosis 38.67 10.59 102 410850 9820 110168527
Osteonecrosis 38.66 10.59 236 410716 33505 110144842
Scopulariopsis infection 38.40 10.59 17 410935 166 110178181
Pulmonary cavitation 38.33 10.59 44 410908 2150 110176197
Herpes simplex oesophagitis 38.31 10.59 23 410929 441 110177906
Epstein Barr virus positive mucocutaneous ulcer 38.31 10.59 33 410919 1134 110177213
Symptom masked 38.27 10.59 41 410911 1854 110176493
Ocular hypertension 38.26 10.59 46 410906 2362 110175985
Urinoma 38.22 10.59 19 410933 246 110178101
Glycosylated haemoglobin increased 38.20 10.59 20 410932 23599 110154748
Nosocomial infection 38.11 10.59 53 410899 3146 110175201
Tendonitis 38.06 10.59 25 410927 26058 110152289
Biopsy kidney abnormal 38.05 10.59 17 410935 170 110178177
Blood calcium increased 38.01 10.59 10 410942 18030 110160317
Emotional disorder 38.01 10.59 7 410945 16153 110162194
Glomerulonephritis rapidly progressive 37.99 10.59 44 410908 2171 110176176
C-reactive protein increased 37.98 10.59 575 410377 217344 109961003
Large intestinal ulcer 37.96 10.59 73 410879 5688 110172659
Peritonitis pneumococcal 37.94 10.59 11 410941 24 110178323
Face oedema 37.88 10.59 41 410911 33428 110144919
Vascular pseudoaneurysm 37.87 10.59 61 410891 4129 110174218
Anuria 37.84 10.59 185 410767 24156 110154191
Swollen joint count 37.78 10.59 93 410859 8581 110169766
Urticaria 37.75 10.59 899 410053 317958 109860389
Scleroderma 37.74 10.59 77 410875 6264 110172083
Peripheral coldness 37.72 10.59 11 410941 18529 110159818
Abnormal behaviour 37.72 10.59 54 410898 38985 110139362
Paranoia 37.60 10.59 18 410934 22356 110155991
Pericarditis constrictive 37.54 10.59 31 410921 1004 110177343
Pregnancy 37.52 10.59 321 410631 50746 110127601
Pyogenic granuloma 37.44 10.59 24 410928 519 110177828
Prostate cancer 37.43 10.59 51 410901 37590 110140757
Ill-defined disorder 37.20 10.59 803 410149 156050 110022297
Intervertebral disc protrusion 37.20 10.59 29 410923 27669 110150678
Hirsutism 37.12 10.59 39 410913 1724 110176623
Blepharospasm 37.09 10.59 94 410858 54757 110123590
Disseminated varicella 37.08 10.59 12 410940 43 110178304
Electrocardiogram QRS complex prolonged 37.05 10.59 3 410949 13018 110165329
Chronic hepatitis 36.96 10.59 39 410913 1733 110176614
Serpiginous choroiditis 36.81 10.59 9 410943 6 110178341
Acanthamoeba infection 36.80 10.59 25 410927 598 110177749
Torsade de pointes 36.75 10.59 19 410933 22581 110155766
Arteriosclerosis coronary artery 36.75 10.59 24 410928 25094 110153253
Hypoaesthesia oral 36.65 10.59 9 410943 16993 110161354
Inflammation 36.60 10.59 959 409993 192279 109986068
Extrapyramidal disorder 36.57 10.59 32 410920 28835 110149512
Oesophageal candidiasis 36.54 10.59 110 410842 11424 110166923
Movement disorder 36.53 10.59 49 410903 36355 110141992
Disseminated Bacillus Calmette-Guerin infection 36.50 10.59 20 410932 320 110178027
Gastrointestinal haemorrhage 36.44 10.59 416 410536 165102 110013245
Temperature regulation disorder 36.37 10.59 3 410949 12823 110165524
Plasmacytoma 36.31 10.59 68 410884 5194 110173153
Osteomyelitis bacterial 36.26 10.59 24 410928 549 110177798
Motor dysfunction 36.14 10.59 23 410929 24383 110153964
Sporotrichosis 36.05 10.59 15 410937 124 110178223
Oral pain 35.97 10.59 52 410900 37392 110140955
Blood stem cell transplant failure 35.86 10.59 26 410926 692 110177655
Haemosiderosis 35.85 10.59 24 410928 560 110177787
Haemorrhoids 35.81 10.59 48 410904 35624 110142723
Emphysematous cystitis 35.74 10.59 25 410927 628 110177719
Granulomatous dermatitis 35.66 10.59 23 410929 503 110177844
Serratia infection 35.64 10.59 43 410909 2216 110176131
Nail disorder 35.63 10.59 104 410848 57831 110120516
Gastroenteritis viral 35.62 10.59 38 410914 31188 110147159
Remission not achieved 35.62 10.59 23 410929 504 110177843
Mesangioproliferative glomerulonephritis 35.61 10.59 18 410934 242 110178105
Pleural mesothelioma malignant 35.30 10.59 16 410936 166 110178181
Prostatic specific antigen increased 35.27 10.59 3 410949 12508 110165839
Foot fracture 35.26 10.59 26 410926 25520 110152827
Arterial occlusive disease 35.22 10.59 7 410945 15301 110163046
Ascites 35.22 10.59 512 410440 92296 110086051
Enthesopathy 35.16 10.59 3 410949 12475 110165872
Aplastic anaemia 35.14 10.59 181 410771 24127 110154220
Splenomegaly 35.13 10.59 182 410770 24316 110154031
Breast cancer female 35.12 10.59 3 410949 12465 110165882
Muscle rigidity 35.11 10.59 23 410929 24008 110154339
Cytokine storm 35.08 10.59 35 410917 1455 110176892
Graft ischaemia 34.95 10.59 15 410937 135 110178212
Renal haemorrhage 34.93 10.59 45 410907 2480 110175867
Sarcoma of skin 34.92 10.59 13 410939 77 110178270
Hepatocellular injury 34.85 10.59 86 410866 50556 110127791
Exposure via skin contact 34.85 10.59 4 410948 13143 110165204
Pharyngeal oedema 34.82 10.59 9 410943 16419 110161928
Renal haematoma 34.74 10.59 29 410923 954 110177393
Electrocardiogram abnormal 34.73 10.59 13 410939 18696 110159651
Bronchial anastomosis complication 34.70 10.59 14 410938 106 110178241
Herpes zoster reactivation 34.69 10.59 21 410931 409 110177938
SARS-CoV-2 viraemia 34.66 10.59 15 410937 138 110178209
Metastatic carcinoma of the bladder 34.66 10.59 18 410934 257 110178090
Lupus-like syndrome 34.63 10.59 265 410687 40527 110137820
Human herpes virus 8 test positive 34.58 10.59 12 410940 56 110178291
Fracture 34.52 10.59 25 410927 24763 110153584
Cytomegalovirus myocarditis 34.50 10.59 13 410939 80 110178267
Chromophobe renal cell carcinoma 34.41 10.59 12 410940 57 110178290
Conjunctivitis 34.40 10.59 45 410907 33747 110144600
Gastritis fungal 34.30 10.59 19 410933 311 110178036
Ageusia 34.27 10.59 15 410937 19630 110158717
Evans syndrome 34.18 10.59 26 410926 746 110177601
Herpes zoster oticus 34.17 10.59 25 410927 675 110177672
Intentional dose omission 33.99 10.59 16 410936 20064 110158283
Lung adenocarcinoma stage IV 33.94 10.59 23 410929 548 110177799
Autoimmune neutropenia 33.83 10.59 25 410927 686 110177661
Asphyxia 33.78 10.59 6 410946 14209 110164138
Faeces discoloured 33.75 10.59 46 410906 33902 110144445
Substance-induced psychotic disorder 33.64 10.59 67 410885 5357 110172990
Urinary tract candidiasis 33.59 10.59 31 410921 1168 110177179
Laryngitis 33.51 10.59 271 410681 42140 110136207
Lactobacillus infection 33.44 10.59 22 410930 498 110177849
Viral test positive 33.32 10.59 27 410925 851 110177496
Achromobacter infection 33.30 10.59 18 410934 280 110178067
Heartland virus infection 33.28 10.59 10 410942 26 110178321
Phaeohyphomycotic brain abscess 33.12 10.59 12 410940 65 110178282
Blood pressure fluctuation 33.08 10.59 154 410798 74670 110103677
Glomerulonephritis membranous 33.04 10.59 39 410913 1964 110176383
Meningitis herpes 33.02 10.59 18 410934 285 110178062
H1N1 influenza 33.01 10.59 48 410904 2970 110175377
Squamous cell carcinoma of the oral cavity 32.99 10.59 25 410927 713 110177634
Seroconversion test negative 32.93 10.59 8 410944 5 110178342
Ileal ulcer 32.69 10.59 37 410915 1780 110176567
Ventricular fibrillation 32.67 10.59 65 410887 41248 110137099
Nasal polyps 32.64 10.59 5 410947 13195 110165152
Bladder transitional cell carcinoma 32.58 10.59 46 410906 2770 110175577
Hallucination, auditory 32.56 10.59 30 410922 26367 110151980
Acanthoma 32.47 10.59 11 410941 47 110178300
Tooth disorder 32.47 10.59 37 410915 29472 110148875
Head discomfort 32.37 10.59 15 410937 18985 110159362
Rotator cuff syndrome 32.32 10.59 11 410941 16783 110161564
Large intestine perforation 32.30 10.59 135 410817 16494 110161853
Hepatic cirrhosis 32.29 10.59 389 410563 67237 110111110
Myocarditis mycotic 32.29 10.59 11 410941 48 110178299
Blood parathyroid hormone decreased 32.27 10.59 5 410947 13084 110165263
Arrhythmia 32.07 10.59 141 410811 69434 110108913
Epilepsy 32.07 10.59 229 410723 99980 110078367
Ventricular remodelling 32.05 10.59 14 410938 132 110178215
Acinetobacter sepsis 32.05 10.59 14 410938 132 110178215
Palmar-plantar erythrodysaesthesia syndrome 32.05 10.59 65 410887 40960 110137387
Renal vessel disorder 31.99 10.59 18 410934 304 110178043
Coinfection 31.96 10.59 14 410938 133 110178214
Faecaloma 31.92 10.59 8 410944 14900 110163447
Concussion 31.90 10.59 3 410949 11535 110166812
Molluscum contagiosum 31.83 10.59 23 410929 609 110177738
Surgery 31.75 10.59 66 410886 41217 110137130
Intestinal obstruction 31.69 10.59 97 410855 53130 110125217
Leukaemia in remission 31.57 10.59 9 410943 18 110178329
Vaginal haemorrhage 31.52 10.59 28 410924 25046 110153301
Secretion discharge 31.49 10.59 18 410934 20226 110158121
Septic embolus 31.47 10.59 41 410911 2285 110176062
Renal cell carcinoma stage I 31.43 10.59 12 410940 77 110178270
Musculoskeletal disorder 31.37 10.59 23 410929 22641 110155706
Intestinal villi atrophy 31.37 10.59 22 410930 555 110177792
Injection site induration 31.36 10.59 3 410949 11380 110166967
Spinal osteoarthritis 31.32 10.59 18 410934 20165 110158182
Zoonotic bacterial infection 31.30 10.59 12 410940 78 110178269
Phospholipidosis 31.28 10.59 18 410934 318 110178029
Asthma 31.21 10.59 700 410252 249591 109928756
Colitis erosive 31.19 10.59 17 410935 269 110178078
Coronavirus infection 31.16 10.59 92 410860 9453 110168894
Emphysematous cholecystitis 31.08 10.59 13 410939 109 110178238
Erectile dysfunction 31.08 10.59 15 410937 18541 110159806
Hyperphosphataemia 31.06 10.59 11 410941 16370 110161977
Cutaneous sporotrichosis 31.04 10.59 12 410940 80 110178267
Stress cardiomyopathy 31.03 10.59 10 410942 15796 110162551
Antisynthetase syndrome 31.03 10.59 17 410935 272 110178075
Psychotic disorder 30.92 10.59 92 410860 50845 110127502
Toxic optic neuropathy 30.90 10.59 31 410921 1297 110177050
Ear discomfort 30.90 10.59 3 410949 11246 110167101
Acute respiratory failure 30.89 10.59 421 410531 74839 110103508
Philadelphia positive chronic myeloid leukaemia 30.82 10.59 15 410937 185 110178162
Metastases to salivary gland 30.79 10.59 12 410940 82 110178265
Myocardiac abscess 30.79 10.59 12 410940 82 110178265
Infected neoplasm 30.76 10.59 22 410930 573 110177774
Diffuse large B-cell lymphoma stage IV 30.72 10.59 26 410926 872 110177475
Bartonellosis 30.65 10.59 10 410942 37 110178310
Bacteriuria 30.62 10.59 32 410920 1406 110176941
Plasma cell myeloma 30.58 10.59 125 410827 62811 110115536
Ulcer haemorrhage 30.53 10.59 165 410787 22406 110155941
Schizophrenia 30.41 10.59 22 410930 21804 110156543
Renal abscess 30.26 10.59 33 410919 1523 110176824
Hospice care 30.22 10.59 5 410947 12468 110165879
Oedema 30.21 10.59 1007 409945 208969 109969378
Neutrophil morphology abnormal 30.19 10.59 13 410939 118 110178229
Hepatocellular carcinoma 30.16 10.59 93 410859 9787 110168560
Acarodermatitis 30.11 10.59 37 410915 1944 110176403
Ligament sprain 30.10 10.59 11 410941 16057 110162290
Herpes simplex reactivation 30.07 10.59 32 410920 1436 110176911
Pulmonary air leakage 30.07 10.59 17 410935 290 110178057
Q fever 30.07 10.59 17 410935 290 110178057
Tongue disorder 29.99 10.59 8 410944 14290 110164057
Abdominal wall abscess 29.98 10.59 33 410919 1539 110176808
Hypertrichosis 29.96 10.59 35 410917 1743 110176604
Pulmonary haemorrhage 29.96 10.59 131 410821 16325 110162022
Staphylococcal skin infection 29.94 10.59 36 410916 1849 110176498
Accident 29.88 10.59 3 410949 10949 110167398
Urinary tract infection pseudomonal 29.81 10.59 39 410913 2183 110176164
Renal artery thrombosis 29.80 10.59 21 410931 534 110177813
Vascular hyalinosis 29.78 10.59 14 410938 159 110178188
Pleural adhesion 29.76 10.59 17 410935 296 110178051
Cyst 29.73 10.59 12 410940 16484 110161863
Pelvic pain 29.72 10.59 11 410941 15931 110162416
Reperfusion injury 29.72 10.59 15 410937 201 110178146
Chronic hepatitis C 29.70 10.59 23 410929 678 110177669
Salmonellosis 29.68 10.59 39 410913 2192 110176155
Second primary malignancy 29.66 10.59 15 410937 18053 110160294
Spindle cell sarcoma 29.65 10.59 16 410936 248 110178099
Body temperature increased 29.61 10.59 104 410848 54609 110123738
Intentional product use issue 29.57 10.59 1164 409788 246742 109931605
Blood loss anaemia 29.54 10.59 15 410937 18010 110160337
Pelvic fracture 29.53 10.59 8 410944 14146 110164201
Removal of renal transplant 29.52 10.59 9 410943 25 110178322
Abscess 29.52 10.59 189 410763 27280 110151067
Pharyngeal polyp 29.51 10.59 8 410944 12 110178335
Idiopathic interstitial pneumonia 29.50 10.59 24 410928 761 110177586
Spinal pain 29.47 10.59 16 410936 18499 110159848
Lung disorder 29.46 10.59 877 410075 179170 109999177
Systemic inflammatory response syndrome 29.45 10.59 111 410841 12932 110165415
Blood immunoglobulin A decreased 29.45 10.59 39 410913 2209 110176138
Blood phosphorus increased 29.27 10.59 12 410940 16328 110162019
Eosinophilic colitis 29.23 10.59 22 410930 621 110177726
Abnormal dreams 29.08 10.59 6 410946 12774 110165573
Urate nephropathy 29.08 10.59 15 410937 211 110178136
Dental caries 29.06 10.59 6 410946 12767 110165580
Synovial cyst 29.03 10.59 4 410948 11426 110166921
Mycotic endophthalmitis 29.00 10.59 19 410933 427 110177920
Hypernatraemia 28.99 10.59 15 410937 17818 110160529
Chromaturia 28.97 10.59 40 410912 29320 110149027
Myelitis transverse 28.94 10.59 40 410912 2361 110175986
Swelling 28.92 10.59 1040 409912 350001 109828346
Tooth infection 28.91 10.59 24 410928 22192 110156155
Optic atrophy 28.90 10.59 41 410911 2480 110175867
Joint tuberculosis 28.89 10.59 15 410937 214 110178133
Hypopnoea 28.86 10.59 4 410948 11376 110166971
Dermatitis allergic 28.85 10.59 23 410929 21701 110156646
Staphylococcal sepsis 28.83 10.59 135 410817 17319 110161028
Psychomotor hyperactivity 28.83 10.59 20 410932 20257 110158090
Nematodiasis 28.77 10.59 9 410943 28 110178319
Skin abrasion 28.70 10.59 12 410940 16139 110162208
Hepatic cancer recurrent 28.69 10.59 17 410935 318 110178029
Inflammatory myofibroblastic tumour 28.59 10.59 15 410937 219 110178128
Pericardial effusion 28.59 10.59 332 410620 56885 110121462
Renal arteriosclerosis 28.53 10.59 20 410932 504 110177843
Diabetic cardiomyopathy 28.53 10.59 9 410943 29 110178318
Atypical mycobacterial lymphadenitis 28.53 10.59 9 410943 29 110178318
Granuloma skin 28.53 10.59 4 410948 11279 110167068
Ejection fraction decreased 28.47 10.59 69 410883 40811 110137536
Herpes simplex viraemia 28.45 10.59 22 410930 647 110177700
Anal ulcer 28.45 10.59 35 410917 1841 110176506
Transitional cell carcinoma metastatic 28.34 10.59 13 410939 139 110178208
Cholangitis 28.20 10.59 128 410824 16207 110162140
Breast cancer metastatic 28.19 10.59 4 410948 11177 110167170
Urosepsis 28.15 10.59 203 410749 30472 110147875
Infectious crystalline keratopathy 28.12 10.59 11 410941 76 110178271
Cardiac murmur 28.06 10.59 30 410922 24598 110153749
Enterocolitis 28.02 10.59 142 410810 18807 110159540
Obstructive nephropathy 28.00 10.59 11 410941 77 110178270
Xanthoma 28.00 10.59 15 410937 229 110178118
Mycobacterium kansasii infection 27.97 10.59 18 410934 392 110177955
Iron deficiency 27.93 10.59 17 410935 18459 110159888
Atrioventricular block first degree 27.93 10.59 9 410943 14216 110164131
Chronic papillomatous dermatitis 27.88 10.59 11 410941 78 110178269
Hyperammonaemia 27.87 10.59 113 410839 13619 110164728
Post infection glomerulonephritis 27.85 10.59 13 410939 145 110178202
Perinephric collection 27.85 10.59 18 410934 395 110177952
Neutrophil count increased 27.85 10.59 54 410898 34598 110143749
Lung neoplasm malignant 27.84 10.59 52 410900 33790 110144557
Upper-airway cough syndrome 27.83 10.59 12 410940 15845 110162502
Drug dependence 27.80 10.59 94 410858 49926 110128421
Ventricular tachycardia 27.78 10.59 94 410858 49915 110128432
Tooth extraction 27.76 10.59 7 410945 12984 110165363
Myasthenia gravis crisis 27.76 10.59 34 410918 1780 110176567
Feeling jittery 27.72 10.59 10 410942 14712 110163635
Central nervous system lesion 27.70 10.59 123 410829 15430 110162917
Liver transplant failure 27.70 10.59 13 410939 147 110178200
Gastric disorder 27.67 10.59 51 410901 33306 110145041
Acute coronary syndrome 27.65 10.59 27 410925 23085 110155262
Renal adenoma 27.63 10.59 10 410942 54 110178293
Biliary tract disorder 27.58 10.59 34 410918 1792 110176555
Gastrointestinal fungal infection 27.57 10.59 23 410929 756 110177591
Tracheitis 27.55 10.59 33 410919 1688 110176659
Intracranial pressure increased 27.49 10.59 94 410858 10441 110167906
Breast cancer stage II 27.38 10.59 185 410767 27190 110151157
Blood iron decreased 27.25 10.59 19 410933 19195 110159152
Hyperparathyroidism 27.25 10.59 50 410902 3760 110174587
Migraine 27.20 10.59 461 410491 171191 110007156
Pneumocephalus 27.10 10.59 19 410933 479 110177868
Splenic infection viral 27.04 10.59 9 410943 36 110178311
Nephritis 27.02 10.59 66 410886 6060 110172287
Ischaemic stroke 26.91 10.59 72 410880 41191 110137156
Mood swings 26.88 10.59 27 410925 22785 110155562
Intervertebral disc degeneration 26.84 10.59 17 410935 18068 110160279
Foetal death 26.83 10.59 13 410939 16032 110162315
Renal necrosis 26.83 10.59 16 410936 303 110178044
Lung diffusion test decreased 26.77 10.59 32 410920 1633 110176714
Biphasic mesothelioma 26.75 10.59 10 410942 60 110178287
Feeding disorder 26.68 10.59 24 410928 21338 110157009
Complications of bone marrow transplant 26.60 10.59 21 410931 637 110177710
Adverse reaction 26.60 10.59 43 410909 29551 110148796
Lupus pneumonitis 26.60 10.59 12 410940 123 110178224
Renal failure 26.59 10.59 1062 409890 225512 109952835
Acute promyelocytic leukaemia 26.56 10.59 34 410918 1862 110176485
Acute graft versus host disease oral 26.53 10.59 11 410941 90 110178257
Plasmodium falciparum infection 26.52 10.59 13 410939 163 110178184
T-cell lymphoma 26.52 10.59 31 410921 1545 110176802
Pyelonephritis fungal 26.50 10.59 16 410936 310 110178037
Febrile bone marrow aplasia 26.50 10.59 16 410936 17449 110160898
Gingivitis ulcerative 26.36 10.59 19 410933 501 110177846
Kaposi sarcoma inflammatory cytokine syndrome 26.31 10.59 13 410939 166 110178181
CEC syndrome 26.30 10.59 8 410944 22 110178325
Radiculopathy 26.28 10.59 20 410932 19316 110159031
Micturition urgency 26.24 10.59 20 410932 19300 110159047
Cutaneous leishmaniasis 26.11 10.59 17 410935 378 110177969
Muscular weakness 26.07 10.59 713 410239 247755 109930592
Dehiscence 26.04 10.59 22 410930 736 110177611
Meningitis viral 26.01 10.59 38 410914 2361 110175986
Meningitis 25.94 10.59 99 410853 11603 110166744
Elbow deformity 25.91 10.59 30 410922 1480 110176867
Blood pressure abnormal 25.90 10.59 27 410925 22397 110155950
Viral sepsis 25.89 10.59 14 410938 218 110178129
Anal incontinence 25.88 10.59 26 410926 21938 110156409
Colon injury 25.80 10.59 17 410935 386 110177961
Pneumonia pneumococcal 25.75 10.59 57 410895 4908 110173439
Hydrocephalus 25.71 10.59 91 410861 10284 110168063
Eructation 25.71 10.59 10 410942 14047 110164300
Blood potassium increased 25.70 10.59 53 410899 33196 110145151
Papilloma 25.69 10.59 19 410933 522 110177825
Drug level above therapeutic 25.66 10.59 98 410854 11490 110166857
Orbital infection 25.64 10.59 13 410939 176 110178171
Tuberculosis of genitourinary system 25.63 10.59 11 410941 99 110178248
Extranodal marginal zone B-cell lymphoma (MALT type) 25.59 10.59 22 410930 754 110177593
Lupus vasculitis 25.58 10.59 20 410932 598 110177749
Ankylosing spondylitis 25.57 10.59 13 410939 15599 110162748
Mucoepidermoid carcinoma of salivary gland 25.54 10.59 12 410940 136 110178211
Retinopathy haemorrhagic 25.53 10.59 11 410941 100 110178247
Systemic scleroderma 25.51 10.59 34 410918 1938 110176409
Product label confusion 25.42 10.59 28 410924 22649 110155698
Encephalopathy 25.38 10.59 433 410519 80622 110097725
External auditory canal atresia 25.25 10.59 7 410945 12 110178335
Nocturia 25.18 10.59 16 410936 16974 110161373
Systemic lupus erythematosus 25.13 10.59 1171 409781 253167 109925180
Sickle cell anaemia with crisis 25.06 10.59 3 410949 9542 110168805
Oesophageal carcinoma 25.03 10.59 6 410946 11518 110166829
Abdominal wall infection 25.02 10.59 12 410940 143 110178204
Renal aneurysm 25.01 10.59 15 410937 287 110178060
Poikiloderma 25.00 10.59 18 410934 474 110177873
Paraspinal abscess 24.94 10.59 17 410935 409 110177938
Cryptococcal fungaemia 24.88 10.59 15 410937 290 110178057
Ophthalmic herpes zoster 24.84 10.59 45 410907 3350 110174997
Tooth abscess 24.82 10.59 20 410932 18769 110159578
Pelvic deformity 24.75 10.59 10 410942 76 110178271
Soft tissue infection 24.67 10.59 57 410895 5050 110173297
Ureteric anastomosis complication 24.65 10.59 8 410944 29 110178318
Anorexia nervosa 24.61 10.59 15 410937 296 110178051
Fibromatosis colli of infancy 24.55 10.59 7 410945 14 110178333
Parametritis 24.55 10.59 7 410945 14 110178333
Acquired plagiocephaly 24.55 10.59 7 410945 14 110178333
Polymorphonuclear chromatin clumping 24.54 10.59 6 410946 4 110178343
Hyperoxaluria 24.52 10.59 16 410936 357 110177990
Antibody test negative 24.51 10.59 9 410943 51 110178296
Trench fever 24.51 10.59 9 410943 51 110178296
Bone tuberculosis 24.49 10.59 21 410931 717 110177630
Exostosis 24.47 10.59 270 410682 45686 110132661
Therapy cessation 24.45 10.59 85 410867 44772 110133575
Nerve injury 24.44 10.59 5 410947 10708 110167639
Meningitis histoplasma 24.44 10.59 8 410944 30 110178317
Tenderness 24.42 10.59 45 410907 29392 110148955
Malacoplakia vesicae 24.42 10.59 10 410942 79 110178268
Giant cell myocarditis 24.36 10.59 9 410943 52 110178295
Device occlusion 24.35 10.59 13 410939 15172 110163175
Osmotic demyelination syndrome 24.31 10.59 34 410918 2029 110176318
Cystoid macular oedema 24.27 10.59 40 410912 2760 110175587
Breast pain 24.25 10.59 4 410948 9996 110168351
Gastrointestinal pain 24.19 10.59 7 410945 11853 110166494
Scratch 24.12 10.59 9 410943 12970 110165377
Neoplasm malignant 24.08 10.59 65 410887 37078 110141269
Trichophytic granuloma 24.08 10.59 9 410943 54 110178293
Blood pressure systolic increased 24.03 10.59 195 410757 82796 110095551
Rhinitis 24.02 10.59 29 410923 22516 110155831
Ureteritis 24.00 10.59 14 410938 254 110178093
Mouth ulceration 23.91 10.59 279 410673 47859 110130488
Mycobacterium marinum infection 23.84 10.59 21 410931 744 110177603
Haematocrit decreased 23.72 10.59 146 410806 65971 110112376
Ecthyma 23.71 10.59 24 410928 1015 110177332
Abdominal pain lower 23.61 10.59 66 410886 37217 110141130
Groin pain 23.60 10.59 14 410938 15414 110162933
Gastric haemorrhage 23.57 10.59 15 410937 15900 110162447
Demyelinating polyneuropathy 23.49 10.59 35 410917 2214 110176133
Subdural haematoma 23.48 10.59 64 410888 36390 110141957
Serratia sepsis 23.48 10.59 14 410938 265 110178082
Gastrointestinal stromal tumour 23.46 10.59 34 410918 2097 110176250
Hepatic infection fungal 23.42 10.59 15 410937 324 110178023
Penile ulceration 23.35 10.59 20 410932 682 110177665
Gait inability 23.32 10.59 668 410284 135708 110042639
Blood 1,25-dihydroxycholecalciferol increased 23.30 10.59 10 410942 90 110178257
Spinal operation 23.28 10.59 6 410946 10966 110167381
Wrong product administered 23.24 10.59 6 410946 10954 110167393
Proctalgia 23.22 10.59 10 410942 13212 110165135
Metastases to lymph nodes 23.19 10.59 114 410838 14918 110163429
Appendicitis 23.19 10.59 44 410908 28420 110149927
Parkinsonism 23.15 10.59 29 410923 22158 110156189
Herpes simplex meningitis 23.11 10.59 10 410942 92 110178255
Osteomyelitis chronic 23.10 10.59 21 410931 776 110177571
Leukoencephalopathy 23.09 10.59 81 410871 9114 110169233
Cystitis 23.08 10.59 147 410805 65889 110112458
Brain herniation 23.06 10.59 79 410873 8784 110169563
Nephrogenic systemic fibrosis 23.05 10.59 58 410894 5425 110172922
Hyperaesthesia 23.04 10.59 13 410939 14714 110163633
Product administered to patient of inappropriate age 23.02 10.59 74 410878 7962 110170385
Therapeutic response shortened 23 10.59 47 410905 29536 110148811
Diarrhoea haemorrhagic 22.99 10.59 117 410835 15522 110162825
Hepatic artery stenosis 22.98 10.59 14 410938 276 110178071
Encephalitis brain stem 22.90 10.59 15 410937 337 110178010
Extrapulmonary tuberculosis 22.89 10.59 18 410934 543 110177804
Arterial rupture 22.87 10.59 22 410930 874 110177473
Herpes simplex test positive 22.86 10.59 19 410933 621 110177726
Endothelial dysfunction 22.86 10.59 15 410937 338 110178009
Antiviral drug level above therapeutic 22.83 10.59 10 410942 95 110178252
Non-cardiac chest pain 22.77 10.59 5 410947 10193 110168154
Metapneumovirus infection 22.66 10.59 36 410916 2408 110175939
Acute hepatitis C 22.63 10.59 14 410938 284 110178063
Blood uric acid increased 22.61 10.59 28 410924 21501 110156846
HIV infection 22.54 10.59 26 410926 1277 110177070
Steroid dependence 22.48 10.59 76 410876 8393 110169954
Small intestine adenocarcinoma 22.48 10.59 13 410939 232 110178115
Vascular pseudoaneurysm ruptured 22.47 10.59 18 410934 558 110177789
Epstein-Barr virus antigen positive 22.47 10.59 10 410942 99 110178248
Chorioretinitis 22.43 10.59 27 410925 1388 110176959
Sinusitis aspergillus 22.41 10.59 14 410938 289 110178058
Bulbar palsy 22.41 10.59 15 410937 350 110177997
Pulmonary sepsis 22.37 10.59 56 410896 5222 110173125
Scleroderma renal crisis 22.32 10.59 22 410930 901 110177446
Papillary renal cell carcinoma 22.26 10.59 15 410937 354 110177993
Hepatitis C RNA increased 22.16 10.59 16 410936 423 110177924
Microsporum infection 22.13 10.59 8 410944 43 110178304
Increased tendency to bruise 22.11 10.59 8 410944 11750 110166597
Blood thyroid stimulating hormone increased 22.09 10.59 9 410943 12292 110166055
Brain oedema 22.07 10.59 194 410758 30904 110147443
Therapeutic response unexpected 22.04 10.59 34 410918 23809 110154538
Genitourinary tract infection 22.04 10.59 14 410938 298 110178049
Bradypnoea 22.03 10.59 3 410949 8646 110169701
Angiopathy 22.00 10.59 77 410875 8653 110169694
Body height decreased 21.98 10.59 6 410946 10557 110167790
Post herpetic neuralgia 21.96 10.59 42 410910 3259 110175088
Respiratory distress 21.96 10.59 369 410583 68505 110109842
Gastroenteritis astroviral 21.90 10.59 12 410940 192 110178155
Clostridial infection 21.78 10.59 62 410890 6240 110172107
Anal fissure 21.75 10.59 5 410947 9876 110168471
Hyposplenism 21.75 10.59 6 410946 10 110178337
Memory impairment 21.74 10.59 561 410391 196383 109981964
Gingival pain 21.74 10.59 16 410936 15720 110162627
Post procedural urine leak 21.69 10.59 11 410941 149 110178198
Bullous erysipelas 21.65 10.59 7 410945 25 110178322
Subcutaneous abscess 21.63 10.59 80 410872 9237 110169110
Genital herpes simplex 21.56 10.59 17 410935 515 110177832
Clostridium difficile infection 21.56 10.59 292 410660 51837 110126510
Polyneuropathy 21.53 10.59 55 410897 31957 110146390
Hepatitis cholestatic 21.49 10.59 125 410827 17441 110160906
Incorrect route of product administration 21.45 10.59 346 410606 63715 110114632
Germ cell cancer 21.42 10.59 12 410940 201 110178146
Cardiac tamponade 21.34 10.59 91 410861 11216 110167131
Transplantation complication 21.34 10.59 16 410936 449 110177898
Live birth 21.33 10.59 370 410582 69114 110109233
Lepromatous leprosy 21.31 10.59 10 410942 113 110178234
Injection site discolouration 21.29 10.59 4 410948 9099 110169248
Ventricular extrasystoles 21.20 10.59 32 410920 22609 110155738
Herpes simplex colitis 21.16 10.59 10 410942 115 110178232
Hepatic cyst infection 21.16 10.59 12 410940 206 110178141
Deafness 21.14 10.59 42 410910 26667 110151680
Schistosomiasis 21.13 10.59 8 410944 50 110178297
Cutaneous T-cell lymphoma stage II 21.13 10.59 8 410944 50 110178297
Ureteric dilatation 21.13 10.59 13 410939 261 110178086
Hepatic cytolysis 21.11 10.59 119 410833 54934 110123413
Sinus node dysfunction 21.11 10.59 4 410948 9043 110169304
Pain of skin 21.09 10.59 26 410926 20003 110158344
Eye infection 21.07 10.59 14 410938 14504 110163843
Hypocomplementaemia 21.05 10.59 14 410938 323 110178024
Extra-axial haemorrhage 21.05 10.59 6 410946 12 110178335
Anosmia 21.01 10.59 10 410942 12462 110165885
Hepatosplenomegaly 21.00 10.59 65 410887 6854 110171493
Bladder transitional cell carcinoma stage III 21.00 10.59 8 410944 51 110178296
Electrolyte imbalance 20.98 10.59 69 410883 36959 110141388
Anhedonia 20.91 10.59 16 410936 15412 110162935
Skin bacterial infection 20.91 10.59 21 410931 880 110177467
Epididymitis 20.88 10.59 35 410917 2449 110175898
Aspergillosis oral 20.87 10.59 8 410944 52 110178295
Staphylococcal mediastinitis 20.87 10.59 8 410944 52 110178295
Thrombotic thrombocytopenic purpura 20.84 10.59 66 410886 7045 110171302
Immunosuppressant drug level 20.84 10.59 7 410945 29 110178318
Musculoskeletal stiffness 20.83 10.59 839 410113 278983 109899364
Hypophosphataemia 20.82 10.59 59 410893 33123 110145224
Haematotoxicity 20.80 10.59 142 410810 20940 110157407
Granulomatous rosacea 20.75 10.59 12 410940 214 110178133
Carotid artery occlusion 20.74 10.59 5 410947 9560 110168787
Hantaviral infection 20.73 10.59 6 410946 13 110178334
Breast cancer stage III 20.71 10.59 411 410541 78706 110099641
Paternal exposure during pregnancy 20.70 10.59 12 410940 215 110178132
Gastroenteritis Escherichia coli 20.67 10.59 25 410927 1292 110177055
Rheumatic disorder 20.66 10.59 43 410909 3548 110174799
Fibrosis 20.66 10.59 69 410883 7573 110170774
Respiratory papilloma 20.65 10.59 7 410945 30 110178317
Aphonia 20.63 10.59 11 410941 12849 110165498
Gouty tophus 20.57 10.59 16 410936 475 110177872
Eosinophilic granulomatosis with polyangiitis 20.56 10.59 7 410945 10679 110167668
Haemoptysis 20.50 10.59 168 410784 71186 110107161
Pneumonia escherichia 20.47 10.59 24 410928 1200 110177147
Cow pox 20.47 10.59 7 410945 31 110178316
Keratouveitis 20.47 10.59 7 410945 31 110178316
Immune effector cell-associated neurotoxicity syndrome 20.46 10.59 15 410937 14767 110163580
Hypertensive crisis 20.45 10.59 37 410915 24335 110154012
Myocarditis infectious 20.43 10.59 10 410942 125 110178222
Rotavirus infection 20.41 10.59 21 410931 906 110177441
Pyuria 20.39 10.59 36 410916 2627 110175720
Bradyphrenia 20.39 10.59 9 410943 11719 110166628
Delayed engraftment 20.37 10.59 13 410939 279 110178068
Viral myelitis 20.36 10.59 10 410942 126 110178221
Creatinine renal clearance decreased 20.27 10.59 31 410921 21784 110156563
Pharyngitis 20.27 10.59 39 410913 25059 110153288
Leiomyosarcoma 20.25 10.59 15 410937 413 110177934
Peptostreptococcus infection 20.24 10.59 11 410941 173 110178174
Spinal fracture 20.24 10.59 33 410919 22600 110155747
Blindness cortical 20.23 10.59 23 410929 1112 110177235
Bronchostenosis 20.20 10.59 21 410931 917 110177430
Tooth loss 20.17 10.59 3 410949 8093 110170254
Eye discharge 20.15 10.59 4 410948 8750 110169597
Cyclosporidium infection 20.13 10.59 6 410946 15 110178332
Pleomorphic malignant fibrous histiocytoma 20.11 10.59 7 410945 33 110178314
Thyroid disorder 20.09 10.59 20 410932 16949 110161398
Cerebral ventricle collapse 20.08 10.59 11 410941 176 110178171
Frustration tolerance decreased 20.07 10.59 4 410948 8727 110169620
Tooth fracture 20.07 10.59 12 410940 13155 110165192
Nephrocalcinosis 20.06 10.59 29 410923 1785 110176562
Human anaplasmosis 20.06 10.59 9 410943 91 110178256
Aphthous ulcer 20.05 10.59 141 410811 20995 110157352
Infection protozoal 20.01 10.59 8 410944 59 110178288
Graft haemorrhage 19.97 10.59 9 410943 92 110178255
Soft tissue sarcoma 19.97 10.59 13 410939 289 110178058
Night sweats 19.89 10.59 645 410307 133338 110045009
Giardiasis 19.86 10.59 17 410935 579 110177768
Leukaemia recurrent 19.81 10.59 39 410913 3092 110175255
Adrenal mass 19.78 10.59 27 410925 1575 110176772
Dyspepsia 19.76 10.59 549 410403 190416 109987931
Cytomegalovirus gastrointestinal ulcer 19.75 10.59 10 410942 135 110178212
CSF protein increased 19.74 10.59 26 410926 1465 110176882
Bacterial translocation 19.72 10.59 26 410926 1466 110176881
Hepatic haematoma 19.70 10.59 21 410931 944 110177403
Capnocytophaga infection 19.70 10.59 11 410941 183 110178164
Pneumonia viral 19.69 10.59 88 410864 11069 110167278
Shock 19.69 10.59 294 410658 53294 110125053
Respiration abnormal 19.63 10.59 6 410946 9803 110168544
Laryngeal disorder 19.62 10.59 23 410929 1150 110177197
Type 1 diabetes mellitus 19.61 10.59 76 410876 8971 110169376
Dysuria 19.58 10.59 137 410815 60094 110118253
Pneumonia respiratory syncytial viral 19.56 10.59 36 410916 2713 110175634
Epithelioid mesothelioma 19.55 10.59 5 410947 5 110178342
Lung consolidation 19.53 10.59 84 410868 10392 110167955
Dermatitis contact 19.52 10.59 14 410938 13939 110164408
Anastomotic stenosis 19.51 10.59 18 410934 678 110177669
Vanishing bile duct syndrome 19.49 10.59 39 410913 3129 110175218
Blood lactic acid increased 19.49 10.59 18 410934 15803 110162544
Mucocutaneous leishmaniasis 19.46 10.59 16 410936 515 110177832
Central nervous system immune reconstitution inflammatory response 19.45 10.59 8 410944 64 110178283
Sexual dysfunction 19.42 10.59 4 410948 8526 110169821
Cervicitis 19.39 10.59 13 410939 304 110178043
Orbital apex syndrome 19.39 10.59 9 410943 99 110178248
Mental impairment 19.33 10.59 34 410918 22605 110155742
Hepatic infection 19.32 10.59 24 410928 1275 110177072
Streptococcal infection 19.30 10.59 86 410866 10804 110167543
Pneumoretroperitoneum 19.28 10.59 11 410941 191 110178156
Incontinence 19.25 10.59 20 410932 16615 110161732
Palatal ulcer 19.24 10.59 12 410940 247 110178100
Viral uveitis 19.18 10.59 11 410941 193 110178154
Humerus fracture 19.16 10.59 8 410944 10768 110167579
Metastases to lung 19.11 10.59 149 410803 22914 110155433
Hypomania 19.11 10.59 7 410945 10203 110168144
Pulse absent 19.11 10.59 9 410943 11283 110167064
Biliary hamartoma 19.10 10.59 6 410946 19 110178328
Pneumonia herpes viral 19.08 10.59 11 410941 195 110178152
Conjunctival melanoma 19.07 10.59 5 410947 6 110178341
Fascial infection 19.07 10.59 5 410947 6 110178341
Tension headache 19.04 10.59 6 410946 9612 110168735
Pseudohypoaldosteronism 19.03 10.59 8 410944 68 110178279
Plasmablastic lymphoma 19.02 10.59 19 410933 791 110177556
Complications of transplanted pancreas 19.01 10.59 7 410945 40 110178307
Arteriovenous fistula occlusion 18.99 10.59 16 410936 533 110177814
Infusion site pain 18.99 10.59 22 410930 17397 110160950
Kidney rupture 18.99 10.59 12 410940 253 110178094
Encephalitis fungal 18.95 10.59 12 410940 254 110178093
Cachexia 18.91 10.59 97 410855 12908 110165439
Actinomycotic sepsis 18.89 10.59 11 410941 199 110178148
General physical health deterioration 18.87 10.59 1343 409609 423952 109754395
Spinal disorder 18.86 10.59 10 410942 11718 110166629
Large intestine polyp 18.86 10.59 17 410935 15100 110163247
Decubitus ulcer 18.86 10.59 24 410928 18212 110160135
Immobile 18.86 10.59 3 410949 7699 110170648
Myocardial necrosis 18.84 10.59 16 410936 539 110177808
Anti-cyclic citrullinated peptide antibody 18.83 10.59 133 410819 19831 110158516
Intestinal ulcer 18.83 10.59 33 410919 2394 110175953
Varicella virus test positive 18.82 10.59 14 410938 388 110177959
Renal amyloidosis 18.81 10.59 13 410939 320 110178027
Hepatitis G 18.78 10.59 9 410943 107 110178240
Hyperventilation 18.78 10.59 5 410947 8942 110169405
Dizziness postural 18.74 10.59 16 410936 14593 110163754
Diverticulum oesophageal 18.74 10.59 11 410941 202 110178145
Jaundice cholestatic 18.74 10.59 16 410936 14592 110163755
Erythropoiesis abnormal 18.70 10.59 17 410935 628 110177719
Apnoea 18.67 10.59 14 410938 13625 110164722
Tuberculous tenosynovitis 18.64 10.59 5 410947 7 110178340
Vitamin B12 deficiency 18.64 10.59 7 410945 10048 110168299
Tongue oedema 18.53 10.59 4 410948 8252 110170095
Granulomatous liver disease 18.51 10.59 26 410926 1558 110176789
Meningitis meningococcal 18.50 10.59 11 410941 207 110178140
Intestine transplant rejection 18.49 10.59 9 410943 111 110178236
Parvovirus B19 test positive 18.47 10.59 10 410942 156 110178191
International normalised ratio decreased 18.47 10.59 4 410948 8232 110170115
Granulicatella bacteraemia 18.43 10.59 6 410946 22 110178325
Pulmonary oedema 18.43 10.59 263 410689 100396 110077951
Herpes simplex encephalitis 18.34 10.59 19 410933 826 110177521
Intracranial infection 18.30 10.59 13 410939 335 110178012
T-cell type acute leukaemia 18.23 10.59 13 410939 337 110178010
Incorrect product administration duration 18.22 10.59 30 410922 20468 110157879
Complication associated with device 18.20 10.59 29 410923 20044 110158303
Fluorosis 18.18 10.59 11 410941 214 110178133
Morganella infection 18.18 10.59 24 410928 1355 110176992
Haemorrhage intracranial 18.18 10.59 176 410776 28793 110149554
Jaundice 18.17 10.59 137 410815 59099 110119248
Infusion site erythema 18.08 10.59 11 410941 11948 110166399
Hypergammaglobulinaemia 18.08 10.59 20 410932 938 110177409
Sphincter of Oddi dysfunction 18.04 10.59 16 410936 572 110177775
Pulmonary congestion 18.03 10.59 57 410895 30909 110147438
Jejunal perforation 18.01 10.59 14 410938 415 110177932
Fibrin D dimer increased 18.01 10.59 7 410945 9838 110168509
Meningism 17.99 10.59 18 410934 751 110177596
Skin induration 17.97 10.59 46 410906 4349 110173998
Product preparation error 17.91 10.59 9 410943 10870 110167477
Renal tuberculosis 17.91 10.59 8 410944 80 110178267
Furuncle 17.90 10.59 5 410947 8663 110169684
Hyperfibrinogenaemia 17.87 10.59 10 410942 167 110178180
Device related infection 17.86 10.59 225 410727 39294 110139053
Myocardial ischaemia 17.83 10.59 46 410906 26638 110151709
Sebaceous carcinoma 17.82 10.59 10 410942 168 110178179
Epiglottic erythema 17.82 10.59 8 410944 81 110178266
Pyelonephritis chronic 17.74 10.59 12 410940 285 110178062
Acute pulmonary histoplasmosis 17.74 10.59 12 410940 285 110178062
Oral discomfort 17.68 10.59 10 410942 11301 110167046
Thyroid tuberculosis 17.65 10.59 6 410946 26 110178321
Sensation of foreign body 17.63 10.59 4 410948 7971 110170376
Beta haemolytic streptococcal infection 17.59 10.59 36 410916 2935 110175412
Eye haemorrhage 17.57 10.59 11 410941 11763 110166584
Sebaceous hyperplasia 17.56 10.59 8 410944 84 110178263
Rhesus antigen positive 17.55 10.59 9 410943 125 110178222
Metastases to skin 17.50 10.59 31 410921 2268 110176079
Corneal graft rejection 17.49 10.59 9 410943 126 110178221
Tongue necrosis 17.49 10.59 9 410943 126 110178221
Fluoride increased 17.48 10.59 8 410944 85 110178262
Meningomyelitis herpes 17.48 10.59 8 410944 85 110178262
Arterial fibrosis 17.47 10.59 6 410946 27 110178320
Splenic vein thrombosis 17.46 10.59 20 410932 975 110177372
Bone infarction 17.45 10.59 16 410936 598 110177749
Abdominal abscess 17.45 10.59 72 410880 8747 110169600
Lymph node tuberculosis 17.39 10.59 21 410931 1083 110177264
Carotid artery thrombosis 17.39 10.59 7 410945 9631 110168716
Aphasia 17.36 10.59 138 410814 58859 110119488
Malabsorption 17.36 10.59 58 410894 6367 110171980
Red blood cell sedimentation rate abnormal 17.36 10.59 41 410911 24468 110153879
Lung squamous cell carcinoma stage IV 17.35 10.59 7 410945 53 110178294
Herpes zoster cutaneous disseminated 17.35 10.59 15 410937 518 110177829
Subcutaneous emphysema 17.34 10.59 33 410919 2551 110175796
Cholangitis sclerosing 17.32 10.59 40 410912 3542 110174805
Cutaneous T-cell lymphoma refractory 17.29 10.59 6 410946 28 110178319
Neuropsychiatric lupus 17.28 10.59 11 410941 235 110178112
Parotitis 17.26 10.59 37 410915 3116 110175231
Infusion site extravasation 17.18 10.59 11 410941 11623 110166724
Bacterial colitis 17.16 10.59 11 410941 238 110178109
Sudden death 17.12 10.59 41 410911 24354 110153993
Coronary artery occlusion 17.11 10.59 20 410932 15752 110162595
Pseudomonal bacteraemia 17.10 10.59 45 410907 4326 110174021
Dermatitis atopic 17.09 10.59 44 410908 25497 110152850
Femoral neck fracture 17.08 10.59 13 410939 12554 110165793
Hypertransaminasaemia 17.05 10.59 151 410801 24104 110154243
Stomatococcal infection 17.03 10.59 13 410939 375 110177972
Isosporiasis 17.02 10.59 10 410942 184 110178163
Lupus myocarditis 17.00 10.59 8 410944 91 110178256
Wound evisceration 17.00 10.59 9 410943 134 110178213
Pneumopericardium 17.00 10.59 11 410941 242 110178105
Food allergy 16.99 10.59 30 410922 19918 110158429
Arterial disorder 16.99 10.59 30 410922 2189 110176158
Cardiovascular disorder 16.99 10.59 37 410915 22723 110155624
Hypophagia 16.96 10.59 120 410832 52506 110125841
Endotoxic shock 16.95 10.59 6 410946 30 110178317
Pulmonary arterial hypertension 16.90 10.59 63 410889 32505 110145842
Double stranded DNA antibody positive 16.90 10.59 15 410937 537 110177810
Peliosis hepatis 16.88 10.59 10 410942 187 110178160
Lip ulceration 16.85 10.59 34 410918 2744 110175603
Lymphadenopathy 16.84 10.59 332 410620 63503 110114844
Japanese spotted fever 16.79 10.59 6 410946 31 110178316
Systemic viral infection 16.76 10.59 9 410943 138 110178209
Hypercalcaemia 16.76 10.59 255 410697 46402 110131945
Renal cyst 16.71 10.59 26 410926 18146 110160201
Thyroid gland abscess 16.70 10.59 8 410944 95 110178252
Respiratory tract inflammation 16.70 10.59 20 410932 1023 110177324
Pancreatic abscess 16.69 10.59 10 410942 191 110178156
Caesarean section 16.69 10.59 16 410936 13801 110164546
Cholangitis infective 16.68 10.59 18 410934 821 110177526
Bundle branch block left 16.68 10.59 14 410938 12874 110165473
Plasma cell myeloma recurrent 16.67 10.59 3 410949 7039 110171308
Atrioventricular block 16.65 10.59 23 410929 16854 110161493
Acute hepatic failure 16.64 10.59 208 410744 36260 110142087
Aortic arteriosclerosis 16.62 10.59 10 410942 10928 110167419
Histology abnormal 16.59 10.59 13 410939 390 110177957
Meningitis pneumococcal 16.57 10.59 17 410935 731 110177616
Anal squamous cell carcinoma 16.45 10.59 18 410934 834 110177513
Lip oedema 16.42 10.59 4 410948 7596 110170751
Neurologic neglect syndrome 16.38 10.59 7 410945 9291 110169056
Pleomorphism 16.37 10.59 5 410947 14 110178333
Nodule 16.36 10.59 64 410888 32567 110145780
Embolic stroke 16.36 10.59 6 410946 8737 110169610
Sluggishness 16.32 10.59 4 410948 7563 110170784
Hepatitis C virus test 16.31 10.59 7 410945 63 110178284
Metastases to central nervous system 16.29 10.59 38 410914 22779 110155568
Breast mass 16.25 10.59 5 410947 8136 110170211
Meningitis listeria 16.22 10.59 22 410930 1275 110177072
Gonococcal infection 16.21 10.59 7 410945 64 110178283
Appetite disorder 16.20 10.59 8 410944 9761 110168586
Lung squamous cell carcinoma metastatic 16.20 10.59 8 410944 102 110178245
Transfusion 16.20 10.59 45 410907 25427 110152920
Tracheobronchitis 16.19 10.59 33 410919 2683 110175664
Disorder of globe 16.17 10.59 4 410948 3 110178344
Moraxella infection 16.15 10.59 17 410935 753 110177594
Nephritis haemorrhagic 16.12 10.59 5 410947 15 110178332
Retinal coloboma 16.12 10.59 5 410947 15 110178332
Iris coloboma 16.12 10.59 5 410947 15 110178332
Trichostasis spinulosa 16.12 10.59 5 410947 15 110178332
Acinetobacter bacteraemia 16.09 10.59 12 410940 334 110178013
Retinal degeneration 16.09 10.59 25 410927 1641 110176706
Postoperative wound infection 16.08 10.59 107 410845 15646 110162701
Skin swelling 16.06 10.59 5 410947 8075 110170272
Enterocolitis fungal 16.05 10.59 6 410946 36 110178311
Left ventricular hypertrophy 16.05 10.59 94 410858 13150 110165197
Coma 16.04 10.59 325 410627 117544 110060803
Atrial tachycardia 16.02 10.59 7 410945 9171 110169176
Oesophageal infection 16.01 10.59 17 410935 761 110177586
Nasal oedema 16.00 10.59 3 410949 6836 110171511
Skin warm 16.00 10.59 7 410945 9163 110169184
Anaplastic large cell lymphoma T- and null-cell types 15.98 10.59 10 410942 207 110178140
Quadriparesis 15.97 10.59 46 410906 4661 110173686
Anastomotic haemorrhage 15.97 10.59 12 410940 338 110178009
Cholangiocarcinoma 15.96 10.59 34 410918 2851 110175496
Atrophy 15.96 10.59 31 410921 2433 110175914
Infertility 15.94 10.59 17 410935 765 110177582
Viral myositis 15.93 10.59 7 410945 67 110178280
Haemoglobin increased 15.93 10.59 7 410945 9140 110169207
Adenovirus test positive 15.93 10.59 8 410944 106 110178241
Arthropod bite 15.92 10.59 8 410944 9663 110168684
Temperature intolerance 15.89 10.59 17 410935 13933 110164414
Funguria 15.88 10.59 5 410947 16 110178331
Myopathy toxic 15.86 10.59 22 410930 1303 110177044
Lymphangiectasia 15.80 10.59 8 410944 108 110178239
Thermal burn 15.78 10.59 5 410947 7983 110170364
Tooth hypoplasia 15.75 10.59 12 410940 345 110178002
Neurosyphilis 15.73 10.59 8 410944 109 110178238
Muscle tightness 15.71 10.59 19 410933 14743 110163604
Pulmonary thrombosis 15.67 10.59 17 410935 13846 110164501
Pharyngeal swelling 15.65 10.59 13 410939 12019 110166328
Joint abscess 15.65 10.59 16 410936 685 110177662
Insulin resistant diabetes 15.64 10.59 4 410948 4 110178343
Transfusion associated graft versus host disease 15.64 10.59 4 410948 4 110178343
Fascioliasis 15.64 10.59 4 410948 4 110178343
Device related bacteraemia 15.59 10.59 21 410931 1209 110177138
Arteritis coronary 15.58 10.59 7 410945 71 110178276
Gamma-glutamyltransferase increased 15.56 10.59 149 410803 61160 110117187
Forced vital capacity decreased 15.56 10.59 27 410925 1943 110176404
Inhibitory drug interaction 15.50 10.59 47 410905 4900 110173447
Mucosal hypertrophy 15.48 10.59 8 410944 113 110178234
Morphoea 15.45 10.59 15 410937 603 110177744
T-lymphocyte count abnormal 15.40 10.59 6 410946 41 110178306
Infective scleritis 15.36 10.59 8 410944 115 110178232
Ureteric obstruction 15.31 10.59 35 410917 3079 110175268
Upper airway necrosis 15.27 10.59 6 410946 42 110178305
Splenic peliosis 15.22 10.59 5 410947 19 110178328
Perihepatic abscess 15.20 10.59 9 410943 168 110178179
Intussusception 15.20 10.59 24 410928 1597 110176750
Tibia fracture 15.17 10.59 3 410949 6582 110171765
Dyspnoea at rest 15.16 10.59 6 410946 8340 110170007
Viral cardiomyopathy 15.15 10.59 6 410946 43 110178304
Hepatic infection bacterial 15.15 10.59 6 410946 43 110178304
Staphylococcal scalded skin syndrome 15.09 10.59 14 410938 531 110177816
Tumour lysis syndrome 15.07 10.59 61 410891 30740 110147607
Oral disorder 15.07 10.59 86 410866 11917 110166430
Epiploic appendagitis 15.06 10.59 9 410943 171 110178176
Sensory disturbance 15.04 10.59 26 410926 17403 110160944
Renal-limited thrombotic microangiopathy 15.03 10.59 14 410938 534 110177813
Neuromyelitis optica spectrum disorder 15.00 10.59 23 410929 1492 110176855
Euphoric mood 14.99 10.59 7 410945 8820 110169527
Pre-existing condition improved 14.98 10.59 3 410949 6523 110171824
Drooling 14.96 10.59 4 410948 7135 110171212
IIIrd nerve paralysis 14.96 10.59 22 410930 1375 110176972
T-cell lymphoma stage IV 14.93 10.59 9 410943 174 110178173
Vitamin D decreased 14.93 10.59 14 410938 12201 110166146
Enamel anomaly 14.91 10.59 10 410942 234 110178113
Marginal zone lymphoma 14.88 10.59 10 410942 235 110178112
Coagulopathy 14.85 10.59 224 410728 40687 110137660
Proctitis 14.84 10.59 25 410927 16902 110161445
Latent autoimmune diabetes in adults 14.84 10.59 9 410943 176 110178171
Raoultella ornithinolytica infection 14.84 10.59 9 410943 176 110178171
Lung squamous cell carcinoma stage II 14.83 10.59 5 410947 21 110178326
Angiosarcoma recurrent 14.83 10.59 5 410947 21 110178326
Cervical dysplasia 14.83 10.59 32 410920 2708 110175639
Pyramidal tract syndrome 14.82 10.59 17 410935 830 110177517
Meningoencephalitis bacterial 14.79 10.59 13 410939 459 110177888
Renal ischaemia 14.78 10.59 29 410923 2294 110176053
Defaecation urgency 14.76 10.59 7 410945 8740 110169607
Viral oesophagitis 14.75 10.59 4 410948 6 110178341
Gastrointestinal toxicity 14.74 10.59 81 410871 11067 110167280
Mouth haemorrhage 14.74 10.59 17 410935 13471 110164876
Renal lymphocele 14.71 10.59 8 410944 126 110178221
Neurosarcoidosis 14.68 10.59 13 410939 464 110177883
Atrioventricular block second degree 14.67 10.59 6 410946 8175 110170172
Spinal cord disorder 14.66 10.59 28 410924 2170 110176177
Vulval ulceration 14.66 10.59 11 410941 309 110178038
Squamous cell carcinoma of the cervix 14.66 10.59 11 410941 309 110178038
Flank pain 14.61 10.59 41 410911 23089 110155258
Escherichia pyelonephritis 14.60 10.59 18 410934 949 110177398
Optic perineuritis 14.59 10.59 6 410946 48 110178299
Pyomyositis 14.57 10.59 16 410936 744 110177603
Renal atrophy 14.57 10.59 29 410923 2317 110176030
Periorbital oedema 14.56 10.59 10 410942 10182 110168165
Diabetes mellitus inadequate control 14.55 10.59 59 410893 29716 110148631
Diabetic neuropathy 14.52 10.59 4 410948 6995 110171352
Hepatic vein occlusion 14.51 10.59 11 410941 314 110178033
Hand fracture 14.49 10.59 6 410946 8116 110170231
Pericarditis infective 14.48 10.59 10 410942 246 110178101
Skin angiosarcoma 14.47 10.59 5 410947 23 110178324
Pseudallescheria infection 14.47 10.59 5 410947 23 110178324
International normalised ratio abnormal 14.43 10.59 3 410949 6354 110171993
Blood glucose abnormal 14.42 10.59 16 410936 12900 110165447
Measles 14.41 10.59 15 410937 656 110177691
Human herpes virus 6 serology positive 14.41 10.59 10 410942 248 110178099
Haemorrhoidal haemorrhage 14.40 10.59 6 410946 8087 110170260
Poor venous access 14.38 10.59 45 410907 24477 110153870
Sinus perforation 14.38 10.59 4 410948 7 110178340
Vestibular nystagmus 14.38 10.59 4 410948 7 110178340
Hypomagnesaemia 14.37 10.59 149 410803 60221 110118126
Intraocular pressure increased 14.37 10.59 79 410873 10797 110167550
Adenomatous polyposis coli 14.36 10.59 11 410941 319 110178028
Blood chloride decreased 14.33 10.59 8 410944 9107 110169240
Hiccups 14.31 10.59 16 410936 12853 110165494
Ophthalmic vein thrombosis 14.30 10.59 10 410942 251 110178096
Streptococcal bacteraemia 14.30 10.59 44 410908 4625 110173722
Kidney duplex 14.29 10.59 5 410947 24 110178323
Restrictive allograft syndrome 14.29 10.59 5 410947 24 110178323
Mucosal ulceration 14.29 10.59 29 410923 2350 110175997
SARS-CoV-2 antibody test negative 14.29 10.59 12 410940 398 110177949
Aortic pseudoaneurysm 14.26 10.59 7 410945 88 110178259
Peripheral vascular disorder 14.26 10.59 7 410945 8569 110169778
Cardiac pacemaker insertion 14.25 10.59 3 410949 6298 110172049
White blood cell count abnormal 14.24 10.59 4 410948 6905 110171442
Lipase increased 14.23 10.59 30 410922 18642 110159705
Internal haemorrhage 14.23 10.59 10 410942 10061 110168286
Diffuse alveolar damage 14.17 10.59 40 410912 4007 110174340
Myocardial calcification 14.13 10.59 10 410942 256 110178091
Hypoplastic anaemia 14.13 10.59 5 410947 25 110178322
Urinary bladder toxicity 14.13 10.59 5 410947 25 110178322
Transplantation associated food allergy 14.12 10.59 8 410944 137 110178210
Respiratory symptom 14.12 10.59 21 410931 14924 110163423
Adult T-cell lymphoma/leukaemia 14.09 10.59 12 410940 406 110177941
Neutrophilic dermatosis 14.03 10.59 16 410936 776 110177571
Parapox virus infection 14.03 10.59 4 410948 8 110178339
High grade B-cell lymphoma Burkitt-like lymphoma stage IV 14.03 10.59 4 410948 8 110178339
Erysipelothrix infection 14.03 10.59 4 410948 8 110178339
Infectious thyroiditis 14.03 10.59 9 410943 195 110178152
Cardiac valve abscess 14.02 10.59 8 410944 139 110178208
Cystitis escherichia 14 10.59 16 410936 778 110177569
Aspiration 14.00 10.59 62 410890 30471 110147876
Oedematous kidney 14.00 10.59 10 410942 260 110178087
Rash papular 13.99 10.59 54 410898 27585 110150762
Vitamin D deficiency 13.98 10.59 30 410922 18522 110159825
Colitis herpes 13.97 10.59 5 410947 26 110178321
Aortitis salmonella 13.97 10.59 5 410947 26 110178321
Autoimmune anaemia 13.97 10.59 5 410947 26 110178321
Bladder hypertrophy 13.96 10.59 19 410933 1105 110177242
Thymoma 13.94 10.59 12 410940 412 110177935
Breast cancer stage I 13.94 10.59 5 410947 7382 110170965
Blood immunoglobulin G decreased 13.93 10.59 48 410904 5352 110172995
Protein-losing gastroenteropathy 13.90 10.59 17 410935 889 110177458
Immune recovery uveitis 13.87 10.59 8 410944 142 110178205
CSF white blood cell count increased 13.87 10.59 8 410944 142 110178205
Chronic cutaneous lupus erythematosus 13.85 10.59 18 410934 1001 110177346
Metastases to retroperitoneum 13.84 10.59 12 410940 416 110177931
Rhabdoid tumour 13.81 10.59 5 410947 27 110178320
Viral acanthoma 13.81 10.59 5 410947 27 110178320
Lupus hepatitis 13.80 10.59 3 410949 0 110178347
Endotoxaemia 13.80 10.59 3 410949 0 110178347
Reflux nephropathy 13.80 10.59 3 410949 0 110178347
Muscle neoplasm 13.79 10.59 6 410946 56 110178291
Metastases to heart 13.74 10.59 12 410940 420 110177927
Encephalitis enteroviral 13.73 10.59 10 410942 268 110178079
Renal cyst infection 13.73 10.59 10 410942 268 110178079
Plasma cell disorder 13.71 10.59 4 410948 9 110178338
Kidney anastomosis 13.71 10.59 4 410948 9 110178338
Anorectal infection bacterial 13.71 10.59 4 410948 9 110178338
Hookworm infection 13.71 10.59 4 410948 9 110178338
Uraemic encephalopathy 13.71 10.59 16 410936 796 110177551
Infusion site swelling 13.70 10.59 10 410942 9867 110168480
VIth nerve paralysis 13.67 10.59 24 410928 1743 110176604
Blood immunoglobulin M increased 13.67 10.59 23 410929 1614 110176733
Infective uveitis 13.66 10.59 5 410947 28 110178319
Wheelchair user 13.66 10.59 6 410946 7836 110170511
Papule 13.65 10.59 74 410878 10059 110168288
Enterocolitis haemorrhagic 13.62 10.59 30 410922 2574 110175773
Hand deformity 13.62 10.59 965 409987 217541 109960806
Urine output decreased 13.60 10.59 123 410829 19753 110158594
Sensory loss 13.57 10.59 38 410914 21419 110156928
Performance status decreased 13.57 10.59 5 410947 7261 110171086
Body mass index abnormal 13.57 10.59 17 410935 911 110177436
Prostatitis 13.56 10.59 44 410908 4757 110173590
Bedridden 13.54 10.59 18 410934 13407 110164940
Hepatic vein stenosis 13.52 10.59 6 410946 59 110178288
Systemic bacterial infection 13.52 10.59 6 410946 59 110178288
Mantle cell lymphoma stage IV 13.52 10.59 6 410946 59 110178288
Meningitis tuberculous 13.51 10.59 20 410932 1258 110177089
White blood cell count increased 13.48 10.59 266 410686 96576 110081771
Right ventricular diastolic collapse 13.48 10.59 7 410945 100 110178247
Upper respiratory tract infection 13.47 10.59 378 410574 130950 110047397
Blood alkaline phosphatase increased 13.46 10.59 184 410768 70751 110107596
Eosinophilic pneumonia 13.45 10.59 5 410947 7222 110171125
Multi-organ disorder 13.42 10.59 35 410917 3346 110175001
Renal arteritis 13.42 10.59 4 410948 10 110178337
Skin cancer metastatic 13.42 10.59 4 410948 10 110178337
Gastroenteritis listeria 13.42 10.59 4 410948 10 110178337
Platelet production decreased 13.42 10.59 4 410948 10 110178337
Euglycaemic diabetic ketoacidosis 13.42 10.59 14 410938 11609 110166738
Agnosia 13.42 10.59 10 410942 278 110178069
Natural killer-cell leukaemia 13.41 10.59 7 410945 101 110178246
Portal vein embolism 13.41 10.59 7 410945 101 110178246
Tenosynovitis 13.41 10.59 25 410927 16258 110162089
Hemianopia homonymous 13.40 10.59 22 410930 1513 110176834
Oculomotor study abnormal 13.38 10.59 5 410947 30 110178317
Opsoclonus myoclonus 13.36 10.59 10 410942 280 110178067
Coma scale abnormal 13.29 10.59 10 410942 9716 110168631
Hunger 13.29 10.59 4 410948 6600 110171747
Oral herpes 13.27 10.59 198 410754 35882 110142465
Endoscopy upper gastrointestinal tract abnormal 13.26 10.59 6 410946 62 110178285
Meningitis aseptic 13.24 10.59 72 410880 9798 110168549
Metastatic malignant melanoma 13.24 10.59 35 410917 3374 110174973
Hyperthermia 13.22 10.59 38 410914 21234 110157113
Restrictive pulmonary disease 13.21 10.59 34 410918 3225 110175122
Visual field defect 13.20 10.59 73 410879 9999 110168348
Pharyngitis streptococcal 13.19 10.59 18 410934 13259 110165088
Tonsil cancer 13.18 10.59 20 410932 1286 110177061
Myocarditis toxoplasmal 13.17 10.59 6 410946 63 110178284
Skin hypertrophy 13.14 10.59 45 410907 5002 110173345
Blindness transient 13.14 10.59 3 410949 5953 110172394
Venous haemorrhage 13.07 10.59 11 410941 366 110177981
Biliary ischaemia 13.06 10.59 7 410945 107 110178240
Reticulocyte count decreased 13.03 10.59 17 410935 949 110177398
Coronary arterial stent insertion 13.01 10.59 3 410949 5912 110172435
Altered state of consciousness 13.00 10.59 144 410808 57482 110120865
Ketoacidosis 13.00 10.59 11 410941 10076 110168271
Platelet count increased 12.98 10.59 52 410900 26282 110152065
Roseolovirus test positive 12.97 10.59 10 410942 293 110178054
Abortion spontaneous 12.95 10.59 189 410763 34093 110144254
Typhoid fever 12.94 10.59 7 410945 109 110178238
Psychomotor skills impaired 12.94 10.59 5 410947 7053 110171294
Hysterectomy 12.93 10.59 7 410945 8107 110170240
Hallucination, visual 12.92 10.59 90 410862 39515 110138832
Arteriospasm coronary 12.90 10.59 9 410943 9091 110169256
Visceral larva migrans 12.90 10.59 4 410948 12 110178335
Metastases to muscle 12.87 10.59 11 410941 374 110177973
Granulicatella infection 12.86 10.59 8 410944 164 110178183
Neurocryptococcosis 12.85 10.59 6 410946 67 110178280
Haemorrhage 12.84 10.59 300 410652 106392 110071955
Nasal cavity cancer 12.82 10.59 10 410942 298 110178049
Supraventricular extrasystoles 12.81 10.59 7 410945 8066 110170281
Sebaceous gland disorder 12.77 10.59 6 410946 68 110178279
Fungating wound 12.77 10.59 6 410946 68 110178279
Encephalitis Japanese B 12.77 10.59 6 410946 68 110178279
Paradoxical drug reaction 12.76 10.59 71 410881 9746 110168601
Bone marrow failure 12.71 10.59 293 410659 57555 110120792
Thinking abnormal 12.69 10.59 23 410929 15117 110163230
Hypoaldosteronism 12.68 10.59 14 410938 655 110177692
Iron overload 12.66 10.59 26 410926 2125 110176222
Lymphadenopathy mediastinal 12.66 10.59 47 410905 5437 110172910
Iliac artery disease 12.66 10.59 4 410948 13 110178334
Epstein-Barr virus test negative 12.66 10.59 4 410948 13 110178334
Oesophageal tuberculosis 12.66 10.59 4 410948 13 110178334
Central nervous system lupus 12.64 10.59 20 410932 1333 110177014
Choking 12.62 10.59 23 410929 15087 110163260
Optic discs blurred 12.62 10.59 6 410946 70 110178277
Hypertensive emergency 12.60 10.59 34 410918 3317 110175030
Wound infection fungal 12.60 10.59 9 410943 234 110178113
Sleep disorder due to general medical condition, hypersomnia type 12.59 10.59 25 410927 1994 110176353
Nephrosclerosis 12.58 10.59 25 410927 1996 110176351
Chronic myeloid leukaemia recurrent 12.58 10.59 11 410941 386 110177961
Weight increased 12.57 10.59 1366 409586 418278 109760069
Pathergy reaction 12.55 10.59 6 410946 71 110178276
Otitis externa 12.51 10.59 30 410922 2722 110175625
Enterococcus test positive 12.50 10.59 31 410921 2873 110175474
Cholecystectomy 12.50 10.59 13 410939 10796 110167551
Lipohypertrophy 12.49 10.59 17 410935 989 110177358
Culture wound positive 12.48 10.59 11 410941 390 110177957
Retinal ischaemia 12.47 10.59 17 410935 990 110177357
Wrong technique in device usage process 12.47 10.59 5 410947 6896 110171451
Type 3 diabetes mellitus 12.45 10.59 7 410945 118 110178229
Necrotising bronchiolitis 12.43 10.59 4 410948 14 110178333
Gallbladder rupture 12.41 10.59 19 410933 1231 110177116
Blood immunoglobulin M decreased 12.40 10.59 25 410927 2016 110176331
Haemorrhagic cyst 12.36 10.59 11 410941 395 110177952
Hip arthroplasty 12.36 10.59 283 410669 55530 110122817
Parathyroid hyperplasia 12.36 10.59 8 410944 176 110178171
Severe acute respiratory syndrome 12.34 10.59 9 410943 242 110178105
Increased appetite 12.33 10.59 23 410929 14954 110163393
Diffuse mesangial sclerosis 12.33 10.59 6 410946 74 110178273
Periodontitis 12.33 10.59 45 410907 5163 110173184
Renal infarct 12.32 10.59 34 410918 3361 110174986
Mucous stools 12.31 10.59 5 410947 6842 110171505
Product availability issue 12.29 10.59 7 410945 7883 110170464
Delusion 12.29 10.59 46 410906 23709 110154638
Pseudopapilloedema 12.27 10.59 5 410947 39 110178308
Pneumonia staphylococcal 12.26 10.59 50 410902 6041 110172306
Serratia bacteraemia 12.26 10.59 6 410946 75 110178272
Alanine aminotransferase abnormal 12.25 10.59 10 410942 9324 110169023
Transient acantholytic dermatosis 12.24 10.59 10 410942 319 110178028
Wound infection staphylococcal 12.24 10.59 34 410918 3375 110174972
Mouth swelling 12.23 10.59 6 410946 7348 110170999
Coxsackie virus test positive 12.22 10.59 4 410948 15 110178332
Respiratory rate decreased 12.21 10.59 4 410948 6254 110172093
Cholecystitis 12.20 10.59 52 410900 25830 110152517
Pancreatic fistula 12.20 10.59 7 410945 123 110178224
Vascular device infection 12.20 10.59 27 410925 16485 110161862
Laryngeal stenosis 12.16 10.59 20 410932 1378 110176969
Hypokinesia 12.14 10.59 41 410911 21785 110156562
Limbic encephalitis 12.13 10.59 15 410937 793 110177554
Photosensitivity reaction 12.13 10.59 147 410805 25442 110152905
Renal artery occlusion 12.13 10.59 8 410944 182 110178165
Peripheral arterial occlusive disease 12.11 10.59 10 410942 9270 110169077
Atypical femur fracture 12.09 10.59 4 410948 6215 110172132
Cryoglobulinaemia 12.08 10.59 19 410933 1260 110177087
Carotid artery stenosis 12.06 10.59 10 410942 9253 110169094
Acute lymphocytic leukaemia recurrent 12.05 10.59 48 410904 5739 110172608
Malignant ascites 12.03 10.59 20 410932 1390 110176957
Squamous cell carcinoma of the tongue 12.03 10.59 15 410937 800 110177547
Renal artery perforation 12.02 10.59 4 410948 16 110178331
Osteomyelitis 12 10.59 197 410755 36403 110141944
Septic pulmonary embolism 11.98 10.59 10 410942 329 110178018
Transient hypogammaglobulinaemia of infancy 11.95 10.59 5 410947 42 110178305
Atrial flutter 11.90 10.59 48 410904 24214 110154133
Immune thrombocytopenia 11.90 10.59 132 410820 22362 110155985
Heart rate abnormal 11.90 10.59 6 410946 7232 110171115
Upper motor neurone lesion 11.85 10.59 10 410942 334 110178013
Varicella zoster sepsis 11.83 10.59 4 410948 17 110178330
Neurofibrosarcoma 11.81 10.59 9 410943 259 110178088
Vascular graft thrombosis 11.81 10.59 9 410943 259 110178088
Drug level changed 11.80 10.59 13 410939 607 110177740
Diverticulum 11.79 10.59 25 410927 15501 110162846
Retroperitoneal neoplasm 11.75 10.59 5 410947 44 110178303
Thyroid stimulating hormone deficiency 11.75 10.59 5 410947 44 110178303
Multiple allergies 11.74 10.59 82 410870 12181 110166166
Sialocele 11.73 10.59 3 410949 3 110178344
Herpes simplex pharyngitis 11.73 10.59 3 410949 3 110178344
Vaginal cancer stage 0 11.73 10.59 3 410949 3 110178344
Sustained viral response 11.73 10.59 3 410949 3 110178344
Pyruvate kinase deficiency anaemia 11.73 10.59 3 410949 3 110178344
Visual agnosia 11.73 10.59 3 410949 3 110178344
Iliac artery rupture 11.73 10.59 3 410949 3 110178344
Bordetella test positive 11.73 10.59 3 410949 3 110178344
Systemic bartonellosis 11.73 10.59 3 410949 3 110178344
Hantavirus pulmonary infection 11.73 10.59 3 410949 3 110178344
Lymphocele marsupialisation 11.73 10.59 3 410949 3 110178344
Bacterial abscess central nervous system 11.73 10.59 3 410949 3 110178344
Cutaneous B-cell lymphoma 11.72 10.59 7 410945 133 110178214
Osteomyelitis acute 11.71 10.59 13 410939 612 110177735
Periorbital swelling 11.70 10.59 3 410949 5502 110172845
T-lymphocyte count decreased 11.70 10.59 13 410939 613 110177734
Spirometry abnormal 11.67 10.59 3 410949 5494 110172853
Multifocal motor neuropathy 11.67 10.59 7 410945 134 110178213
Aortic valve disease mixed 11.67 10.59 7 410945 134 110178213
Ultrasound kidney abnormal 11.66 10.59 6 410946 84 110178263
Renal cancer 11.66 10.59 19 410933 13015 110165332
Keratoacanthoma 11.64 10.59 20 410932 1428 110176919
Skin hypopigmentation 11.61 10.59 20 410932 1431 110176916
Birdshot chorioretinopathy 11.59 10.59 6 410946 85 110178262
Portal hypertension 11.59 10.59 63 410889 8574 110169773
Feeling hot 11.58 10.59 254 410698 90852 110087495
Hepatic failure 11.56 10.59 336 410616 68403 110109944
Fat necrosis 11.55 10.59 16 410936 946 110177401
Femoral nerve palsy 11.53 10.59 6 410946 86 110178261
Diverticulum intestinal 11.53 10.59 16 410936 11703 110166644
Genital lesion 11.52 10.59 12 410940 525 110177822
Catheter site erythema 11.51 10.59 4 410948 6024 110172323
Blood magnesium decreased 11.51 10.59 37 410915 19959 110158388
Hyperprolactinaemia 11.50 10.59 5 410947 6570 110171777
Hepatic haemorrhage 11.49 10.59 19 410933 1315 110177032
Blood pressure diastolic decreased 11.48 10.59 82 410870 35803 110142544
Echo virus infection 11.47 10.59 4 410948 19 110178328
Urinary bladder haematoma 11.47 10.59 4 410948 19 110178328
Surgical procedure repeated 11.46 10.59 14 410938 731 110177616
Gastroduodenal ulcer 11.44 10.59 16 410936 955 110177392
Walking aid user 11.43 10.59 143 410809 24932 110153415
Muscle abscess 11.43 10.59 20 410932 1449 110176898
Epigastric discomfort 11.41 10.59 10 410942 9005 110169342
Ocular discomfort 11.38 10.59 9 410943 8524 110169823
Splenic candidiasis 11.35 10.59 6 410946 89 110178258
Prothrombin time prolonged 11.35 10.59 30 410922 17231 110161116
Purpura fulminans 11.33 10.59 10 410942 355 110177992
Metastases to abdominal wall 11.33 10.59 8 410944 204 110178143
Palmoplantar keratoderma 11.32 10.59 3 410949 5384 110172963
Blood triglycerides increased 11.32 10.59 48 410904 23878 110154469
Mood altered 11.32 10.59 41 410911 21334 110157013
Asymptomatic bacteriuria 11.31 10.59 11 410941 443 110177904
Pulmonary pneumatocele 11.30 10.59 4 410948 20 110178327
Adverse drug reaction 11.30 10.59 302 410650 105257 110073090
Splenic neoplasm malignancy unspecified 11.28 10.59 5 410947 49 110178298
Arteriovenous fistula 11.27 10.59 20 410932 1465 110176882
Microtia 11.27 10.59 3 410949 4 110178343
Nail candida 11.27 10.59 3 410949 4 110178343
Colorectal adenocarcinoma 11.27 10.59 12 410940 539 110177808
Red cell distribution width increased 11.26 10.59 31 410921 17571 110160776
Portal vein thrombosis 11.23 10.59 54 410898 7004 110171343
Enterobacter bacteraemia 11.22 10.59 20 410932 1470 110176877
Dermatomyositis 11.22 10.59 39 410913 4367 110173980
Metapneumovirus pneumonia 11.20 10.59 8 410944 208 110178139
Pseudoaneurysm infection 11.20 10.59 8 410944 208 110178139
Progressive bulbar palsy 11.18 10.59 6 410946 92 110178255
Diverticulitis intestinal perforated 11.16 10.59 12 410940 545 110177802
Burkholderia pseudomallei infection 11.14 10.59 7 410945 146 110178201
Tropical spastic paresis 11.14 10.59 4 410948 21 110178326
Grip strength decreased 11.14 10.59 383 410569 79791 110098556
Gastric ulcer 11.14 10.59 209 410743 39618 110138729
Thrombosis in device 11.14 10.59 3 410949 5324 110173023
Joint effusion 11.14 10.59 40 410912 20865 110157482
Glossodynia 11.13 10.59 964 409988 221040 109957307
Red blood cell sedimentation rate increased 11.12 10.59 375 410577 77927 110100420
Visual impairment 11.11 10.59 398 410554 134030 110044317
Pyelocaliectasis 11.10 10.59 17 410935 1102 110177245
Concomitant disease aggravated 11.10 10.59 28 410924 16336 110162011
Dysphoria 11.07 10.59 5 410947 6423 110171924
Endocarditis enterococcal 11.06 10.59 10 410942 367 110177980
Hypertonia 11.04 10.59 9 410943 8397 110169950
Intensive care unit acquired weakness 11.03 10.59 26 410926 2333 110176014
Fibrosarcoma 11.02 10.59 5 410947 52 110178295
Lower motor neurone lesion 11.02 10.59 5 410947 52 110178295
Large intestinal stenosis 11.00 10.59 35 410917 3745 110174602
Skin infection 10.97 10.59 130 410822 22379 110155968
Pancreatic pseudoaneurysm 10.95 10.59 6 410946 96 110178251
Cytomegalovirus test 10.94 10.59 5 410947 53 110178294
Retinal infiltrates 10.94 10.59 5 410947 53 110178294
Actinomycotic pulmonary infection 10.94 10.59 5 410947 53 110178294
Embryonal rhabdomyosarcoma 10.94 10.59 5 410947 53 110178294
Mononucleosis syndrome 10.94 10.59 8 410944 216 110178131
Tearfulness 10.91 10.59 7 410945 7388 110170959
Tumour haemorrhage 10.88 10.59 3 410949 5242 110173105
Tuberculosis liver 10.84 10.59 6 410946 98 110178249
Pleural mesothelioma 10.84 10.59 6 410946 98 110178249
Amenorrhoea 10.79 10.59 11 410941 9220 110169127
Decreased activity 10.78 10.59 15 410937 10959 110167388
Schwannoma 10.78 10.59 7 410945 155 110178192
Pancreas transplant 10.77 10.59 5 410947 55 110178292
Abscess limb 10.75 10.59 61 410891 8436 110169911
Lipids abnormal 10.74 10.59 13 410939 672 110177675
Venous thrombosis 10.72 10.59 61 410891 8444 110169903
Pulmonary function test decreased 10.70 10.59 62 410890 8638 110169709
Echopraxia 10.70 10.59 5 410947 56 110178291
CSF culture positive 10.70 10.59 5 410947 56 110178291
Focal nodular hyperplasia 10.69 10.59 15 410937 898 110177449
Peripancreatic fluid collection 10.68 10.59 6 410946 101 110178246
Wound sepsis 10.65 10.59 8 410944 225 110178122
Vaginal infection 10.65 10.59 6 410946 6798 110171549
Pleuritic pain 10.65 10.59 28 410924 16112 110162235
Extra dose administered 10.62 10.59 18 410934 12141 110166206
Purtscher retinopathy 10.59 10.59 8 410944 227 110178120

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000900 Anti-Bacterial Agents
MeSH PA D000903 Antibiotics, Antineoplastic
MeSH PA D000904 Antibiotics, Antitubercular
MeSH PA D000970 Antineoplastic Agents
MeSH PA D000995 Antitubercular Agents
MeSH PA D004791 Enzyme Inhibitors
FDA EPC N0000175613 Antimetabolite Immunosuppressant
CHEBI has role CHEBI:22587 antiviral agent
CHEBI has role CHEBI:35526 hypoglycemic agent
CHEBI has role CHEBI:35554 cardiovascular drug
CHEBI has role CHEBI:35610 antineoplastic agent
CHEBI has role CHEBI:35674 antihypertensive agent
CHEBI has role CHEBI:35705 immunosuppressive agent
CHEBI has role CHEBI:35842 antirheumatic drug
CHEBI has role CHEBI:35845 gout suppressant
CHEBI has role CHEBI:50266 prodrug
CHEBI has role CHEBI:50671 antithyroid drug
CHEBI has role CHEBI:50748 antipsoriatic
CHEBI has role CHEBI:53746 EC 1.1.1.205 (IMP dehydrogenase) inhibitor
CHEBI has role CHEBI:64946 anti-HIV agent
CHEBI has role CHEBI:66981 ophthalmology drug
CHEBI has role CHEBI:67079 anti-inflammatory agent
CHEBI has role CHEBI:75835 anti-anaemic agent
CHEBI has role CHEBI:76595 nephroprotective agent
CHEBI has role CHEBI:149553 anticoronaviral agent
CHEBI has role CHEBI:231911 renoprotective agent
CHEBI has role CHEBI:233423 antifibrotic agent
CHEBI has role CHEBI:25442 mycotoxin
CHEBI has role CHEBI:33281 antimicrobial agent
CHEBI has role CHEBI:35703 xenobiotic
CHEBI has role CHEBI:76964 <em>Penicillium</em> metabolite
CHEBI has role CHEBI:78298 environmental contaminant

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
The suppression of graft-versus-host disease in hematopoietic stem cell transplantation indication 234646005
Prevention of Cardiac Transplant Rejection indication
Prevention of Liver Transplant Rejection indication
Prevention of Kidney Transplant Rejection indication
Prevention of Lung Transplant Rejection off-label use
Herpes zoster contraindication 4740000 DOID:8536
Progressive multifocal leukoencephalopathy contraindication 22255007 DOID:643
Cytomegalovirus infection contraindication 28944009
Constitutional aplastic anemia contraindication 28975000 DOID:1342
Gastrointestinal ulcer contraindication 40845000
Gastrointestinal perforation contraindication 51875005
Acute nephropathy contraindication 58574008
Acute infectious disease contraindication 63171007
Gastrointestinal hemorrhage contraindication 74474003
Herpes simplex contraindication 88594005 DOID:8566
Malignant lymphoma contraindication 118600007 DOID:0060058
Deficiency of hypoxanthine phosphoribosyltransferase contraindication 124275001
Disease of liver contraindication 235856003 DOID:409
Pregnancy, function contraindication 289908002
Neutropenic disorder contraindication 303011007 DOID:1227
Bone marrow depression contraindication 307762000
Primary malignant neoplasm contraindication 372087000
Malignant neoplasm of skin contraindication 372130007 DOID:4159
Breastfeeding (mother) contraindication 413712001
Opportunistic Fungal Infection contraindication
BK Polyomavirus Reactivation Nephropathy contraindication




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 11.03 acidic
pKa2 6.33 Basic

Orange Book patent data (new drug applications)

Formulation strengthTrade nameApplicantApplication numberApproval dateTypeDose formRoutePatent numberPatent expiration datePatent use
200MG/ML MYHIBBIN AZURITY N216482 May 1, 2024 RX SUSPENSION ORAL 11931455 Aug. 16, 2039 PROPHYLAXIS OF ORGAN REJECTION
200MG/ML MYHIBBIN AZURITY N216482 May 1, 2024 RX SUSPENSION ORAL 12097285 Aug. 16, 2039 PROPHYLAXIS OF ORGAN REJECTION
200MG/ML MYHIBBIN AZURITY N216482 May 1, 2024 RX SUSPENSION ORAL 12194143 Aug. 16, 2039 PROPHYLAXIS OF ORGAN REJECTION
200MG/ML MYHIBBIN AZURITY N216482 May 1, 2024 RX SUSPENSION ORAL 12226526 Aug. 16, 2039 PROPHYLAXIS OF ORGAN REJECTION

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Inosine-5'-monophosphate dehydrogenase 1 Enzyme INHIBITOR Ki 7.48 SCIENTIFIC LITERATURE SCIENTIFIC LITERATURE
Inosine-5'-monophosphate dehydrogenase 2 Enzyme INHIBITOR Ki 8.16 SCIENTIFIC LITERATURE SCIENTIFIC LITERATURE

External reference:

IDSource
4020921 VUID
N0000148406 NUI
D00752 KEGG_DRUG
116680-01-4 SECONDARY_CAS_RN
4020921 VANDF
4021128 VANDF
4021418 VANDF
C0209368 UMLSCUI
MOA PDB_CHEM_ID
CHEMBL1456 ChEMBL_ID
CHEMBL1200955 ChEMBL_ID
D009173 MESH_DESCRIPTOR_UI
DB00688 DRUGBANK_ID
6831 IUPHAR_LIGAND_ID
9242ECW6R0 UNII
5281078 PUBCHEM_CID
237112 RXNORM
164451 MMSL
18132 MMSL
210716 MMSL
5141 MMSL
7547 MMSL
d03839 MMSL
d05217 MMSL
005013 NDDF
005014 NDDF
007639 NDDF
386976000 SNOMEDCT_US
409330005 SNOMEDCT_US
409331009 SNOMEDCT_US
441632007 SNOMEDCT_US
C0026933 UMLSCUI
CHEBI:8764 CHEBI
DB01024 DRUGBANK_ID
24280-93-1 SECONDARY_CAS_RN
446541 PUBCHEM_CID
2950 INN_ID
CHEBI:168396 CHEBI

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
CellCept HUMAN PRESCRIPTION DRUG LABEL 1 0004-0259 CAPSULE 250 mg ORAL NDA 36 sections
CellCept HUMAN PRESCRIPTION DRUG LABEL 1 0004-0260 TABLET, FILM COATED 500 mg ORAL NDA 36 sections
CellCept HUMAN PRESCRIPTION DRUG LABEL 1 0004-0261 POWDER, FOR SUSPENSION 200 mg ORAL NDA 36 sections
CellCept HUMAN PRESCRIPTION DRUG LABEL 1 0004-0298 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 500 mg INTRAVENOUS NDA 36 sections
Mycophenolate Mofetil HUMAN PRESCRIPTION DRUG LABEL 1 0054-0163 CAPSULE 250 mg ORAL ANDA 30 sections
Mycophenolate Mofetil HUMAN PRESCRIPTION DRUG LABEL 1 0054-0166 TABLET 500 mg ORAL ANDA 30 sections
Mycophenolate Mofetil HUMAN PRESCRIPTION DRUG LABEL 1 0093-7334 CAPSULE 250 mg ORAL ANDA 30 sections
Mycophenolate Mofetil HUMAN PRESCRIPTION DRUG LABEL 1 0378-2250 CAPSULE 250 mg ORAL ANDA 31 sections
Mycophenolate Mofetil HUMAN PRESCRIPTION DRUG LABEL 1 0378-4472 TABLET, FILM COATED 500 mg ORAL ANDA 31 sections
Mycophenolate Mofetil HUMAN PRESCRIPTION DRUG LABEL 1 0527-5160 POWDER, FOR SUSPENSION 200 mg ORAL ANDA 36 sections
Mycophenolate Mofetil HUMAN PRESCRIPTION DRUG LABEL 1 0527-5160 POWDER, FOR SUSPENSION 200 mg ORAL ANDA 36 sections
Mycophenolate Mofetil HUMAN PRESCRIPTION DRUG LABEL 1 0781-2067 CAPSULE 250 mg ORAL ANDA 30 sections
Mycophenolate Mofetil HUMAN PRESCRIPTION DRUG LABEL 1 0781-5175 TABLET, FILM COATED 500 mg ORAL ANDA 30 sections
Mycophenolate mofetil HUMAN PRESCRIPTION DRUG LABEL 1 0904-7078 TABLET, FILM COATED 500 mg ORAL ANDA 29 sections
mycophenolate mofetil HUMAN PRESCRIPTION DRUG LABEL 1 0904-7466 CAPSULE 250 mg ORAL ANDA 30 sections
mycophenolate mofetil HUMAN PRESCRIPTION DRUG LABEL 1 16729-019 TABLET 500 mg ORAL ANDA 33 sections
mycophenolate mofetil HUMAN PRESCRIPTION DRUG LABEL 1 16729-094 CAPSULE 250 mg ORAL ANDA 33 sections
CellCept HUMAN PRESCRIPTION DRUG LABEL 1 21695-171 CAPSULE 250 mg ORAL NDA 28 sections
Mycophenolate mofetil HUMAN PRESCRIPTION DRUG LABEL 1 23155-830 CAPSULE 250 mg ORAL ANDA 27 sections
Mycophenolate mofetil HUMAN PRESCRIPTION DRUG LABEL 1 23155-836 TABLET, FILM COATED 500 mg ORAL ANDA 27 sections
MYCOPHENOLATE MOFETIL HUMAN PRESCRIPTION DRUG LABEL 1 23155-848 POWDER, FOR SUSPENSION 200 mg ORAL ANDA 28 sections
MYHIBBIN Human Prescription Drug Label 1 24338-018 SUSPENSION 200 mg ORAL NDA 32 sections
Mycophenolate Mofetil HUMAN PRESCRIPTION DRUG LABEL 1 31722-878 CAPSULE 250 mg ORAL ANDA 29 sections
Mycophenolate Mofetil HUMAN PRESCRIPTION DRUG LABEL 1 31722-879 TABLET, FILM COATED 500 mg ORAL ANDA 30 sections
Mycophenolate Mofetil HUMAN PRESCRIPTION DRUG LABEL 1 42023-172 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 500 mg INTRAVENOUS ANDA 32 sections
Mycophenolate mofetil HUMAN PRESCRIPTION DRUG LABEL 1 42543-988 CAPSULE 250 mg ORAL ANDA 27 sections
Mycophenolate mofetil HUMAN PRESCRIPTION DRUG LABEL 1 42543-989 TABLET, FILM COATED 500 mg ORAL ANDA 27 sections
Mycophenolate Mofetil Human Prescription Drug Label 1 50090-4275 TABLET, FILM COATED 500 mg ORAL ANDA 30 sections
mycophenolate mofetil HUMAN PRESCRIPTION DRUG LABEL 1 50268-557 CAPSULE 250 mg ORAL ANDA 30 sections
Mycophenolate Mofetil HUMAN PRESCRIPTION DRUG LABEL 1 50268-558 TABLET, FILM COATED 500 mg ORAL ANDA 30 sections