mosapramine Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
substances of the imipramine group 1847 89419-40-9

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • Y-516
  • mosapramine HCl
  • mosapramine hydrochloride
  • cremin
  • mosapramine
  • clospipramine
  • Molecular weight: 479.07
  • Formula: C28H35ClN4O
  • CLOGP: 5.93
  • LIPINSKI: 1
  • HAC: 5
  • HDO: 1
  • TPSA: 38.82
  • ALOGS: -4.43
  • ROTB: 4

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None PMDA

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
ATC N05AX10 NERVOUS SYSTEM
PSYCHOLEPTICS
ANTIPSYCHOTICS
Other antipsychotics

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Schizophrenia indication 58214004 DOID:5419

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 13.62 acidic
pKa2 8.63 Basic
pKa3 6.34 Basic
pKa4 5.67 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D01548 KEGG_DRUG
04UZQ7O9SJ UNII
6704 INN_ID
C046384 MESH_SUPPLEMENTAL_RECORD_UI
CHEBI:135775 CHEBI
DB13676 DRUGBANK_ID
CHEMBL2106650 ChEMBL_ID
4257 PUBCHEM_CID

Pharmaceutical products:

None