methylprednisolone suleptanate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| prednisone and prednisolone derivatives | 1772 | 90350-40-6 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
prodrug of methylprednisolone
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| S (Water solubility) | 0.12 mg/mL | Bocci G, Oprea TI, Benet LZ |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| FDA MoA | N0000175450 | Corticosteroid Hormone Receptor Agonists |
| FDA EPC | N0000175576 | Corticosteroid |
| MeSH PA | D000893 | Anti-Inflammatory Agents |
| MeSH PA | D000932 | Antiemetics |
| MeSH PA | D002491 | Central Nervous System Agents |
| MeSH PA | D005765 | Gastrointestinal Agents |
| MeSH PA | D005938 | Glucocorticoids |
| MeSH PA | D006728 | Hormones |
| MeSH PA | D018696 | Neuroprotective Agents |
| MeSH PA | D018373 | Peripheral Nervous System Agents |
| MeSH PA | D020011 | Protective Agents |
| CHEBI has role | CHEBI:35472 | anti-inflammatory drugs |
| CHEBI has role | CHEBI:35703 | Xenobiotic |
| CHEBI has role | CHEBI:37962 | adrenergic agents |
| CHEBI has role | CHEBI:50919 | antiemetico |
| CHEBI has role | CHEBI:63726 | neuroprotective agents |
| CHEBI has role | CHEBI:78298 | environmental contaminants |
| CHEBI has role | CHEBI:49167 | anti-asthmatic drugs |
| CHEBI has role | CHEBI:50266 | Prodrugs |
| CHEBI has role | CHEBI:63562 | glucocorticoid receptor agonists |
| CHEBI has role | CHEBI:67079 | anti-inflammatory agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 0.58 | acidic |
| pKa2 | 12.63 | acidic |
| pKa3 | 13.35 | acidic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D05002 | KEGG_DRUG |
| 4018068 | VANDF |
| C0066429 | UMLSCUI |
| CHEBI:135864 | CHEBI |
| CHEBI:6888 | CHEBI |
| CHEMBL2106453 | ChEMBL_ID |
| CHEMBL1697783 | ChEMBL_ID |
| C052305 | MESH_SUPPLEMENTAL_RECORD_UI |
| 5945 | INN_ID |
| G6CS53NCVS | UNII |
| 23663977 | PUBCHEM_CID |
| DB00959 | DRUGBANK_ID |
| 6902 | RXNORM |
| 1041 | MMSL |
| 5093 | MMSL |
| d00293 | MMSL |
| 002160 | NDDF |
| 116593003 | SNOMEDCT_US |
| 27242001 | SNOMEDCT_US |
| C0025815 | UMLSCUI |
| 732 | INN_ID |
| 6741 | PUBCHEM_CID |
| D008775 | MESH_DESCRIPTOR_UI |
Pharmaceutical products:
None