methylprednisolone succinate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
prednisone and prednisolone derivatives 1771 2921-57-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • methylprednisolone succinate
  • methylprednisolone hemisuccinate
  • methylprednisolone sodium succinate
A water-soluble ester of METHYLPREDNISOLONE used for cardiac, allergic, and hypoxic emergencies.
  • Molecular weight: 474.55
  • Formula: C26H34O8
  • CLOGP: 2.05
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 3
  • TPSA: 138.20
  • ALOGS: -4.25
  • ROTB: 7
  • Status: OFP
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

PropertyValueReference
S (Water solubility) 0.12 mg/mL Bocci G, Oprea TI, Benet LZ

Approvals:

DateAgencyCompanyOrphan
May 18, 1959 FDA PHARMACIA AND UPJOHN

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Cytomegalovirus infection 837.98 9.78 674 243864 20278 63224206
Off label use 719.65 9.78 4743 239795 669719 62574765
Blood pressure fluctuation 591.73 9.78 808 243730 45509 63198975
Infusion related reaction 543.20 9.78 2124 242414 243397 63001087
Completed suicide 499.75 9.78 13 244525 145660 63098824
Product use in unapproved indication 411.01 9.78 1568 242970 177512 63066972
Oxygen saturation decreased 409.86 9.78 993 243545 87592 63156892
Blood pressure diastolic abnormal 407.62 9.78 382 244156 14160 63230324
Drug ineffective for unapproved indication 395.94 9.78 568 243970 33495 63210989
Blood pressure systolic abnormal 387.49 9.78 358 244180 13028 63231456
Lymphocyte count decreased 356.76 9.78 508 244030 29749 63214735
Blood pressure increased 346.61 9.78 1388 243150 160674 63083810
Blood pressure systolic increased 340.79 9.78 636 243902 46761 63197723
Product dose omission issue 332.44 9.78 250 244288 234063 63010421
Transplant rejection 330.98 9.78 298 244240 10482 63234002
Urine abnormality 322.15 9.78 245 244293 6774 63237710
Throat irritation 320.60 9.78 544 243994 37103 63207381
Toxicity to various agents 290.77 9.78 314 244224 246936 62997548
Cytomegalovirus viraemia 285.66 9.78 209 244329 5440 63239044
Glossodynia 281.62 9.78 170 244368 178706 63065778
Alopecia 272.94 9.78 556 243982 336980 62907504
Posterior reversible encephalopathy syndrome 262.46 9.78 329 244209 17016 63227468
Urine leukocyte esterase positive 251 9.78 162 244376 3417 63241067
Aspergillus infection 250.98 9.78 225 244313 7868 63236616
Heart rate decreased 248.38 9.78 545 243993 45015 63199469
Haemophagocytic lymphohistiocytosis 247.04 9.78 252 244286 10375 63234109
Death 240.88 9.78 695 243843 373686 62870798
Blood pressure diastolic decreased 239.84 9.78 362 244176 22344 63222140
Pemphigus 232.28 9.78 219 244319 183507 63060977
Multiple organ dysfunction syndrome 231.85 9.78 607 243931 56145 63188339
Thrombotic microangiopathy 226.75 9.78 240 244298 10321 63234163
Urinary sediment present 219.76 9.78 125 244413 2078 63242406
Systemic lupus erythematosus 219.26 9.78 290 244248 208628 63035856
Abdominal discomfort 215.75 9.78 583 243955 320302 62924182
Erythema 208.64 9.78 1273 243265 174478 63070006
Red blood cells urine positive 205.79 9.78 136 244402 2990 63241494
White blood cells urine positive 204.20 9.78 165 244373 4993 63239491
Bronchopulmonary aspergillosis 199.33 9.78 204 244334 8431 63236053
Swelling 192.93 9.78 490 244048 274888 62969596
Heart rate increased 191.65 9.78 795 243743 93443 63151041
Intentional overdose 190.41 9.78 29 244509 74123 63170361
Injection site pain 188.47 9.78 135 244403 129665 63114819
Drug abuse 187.04 9.78 28 244510 72490 63171994
Contraindicated product administered 186.61 9.78 346 244192 217302 63027182
Post transplant lymphoproliferative disorder 184.63 9.78 154 244384 4877 63239607
Polyomavirus-associated nephropathy 182.04 9.78 104 244434 1744 63242740
Wound 180.24 9.78 218 244320 163045 63081439
Synovitis 179.73 9.78 276 244262 186642 63057842
Arthropathy 179.38 9.78 399 244139 234393 63010091
Pneumocystis jirovecii pneumonia 179.11 9.78 270 244268 16644 63227840
Kidney transplant rejection 176.26 9.78 140 244398 4131 63240353
Confusional state 171.49 9.78 413 244125 235967 63008517
Fall 169.51 9.78 856 243682 391478 62853006
Crystal urine present 168.09 9.78 95 244443 1559 63242925
Complications of transplanted kidney 165.70 9.78 109 244429 2377 63242107
Cytomegalovirus test positive 164.81 9.78 117 244421 2901 63241583
Flushing 152.29 9.78 633 243905 74454 63170030
BK virus infection 151.67 9.78 115 244423 3164 63241320
Lymphopenia 150.96 9.78 261 244277 18066 63226418
Irritable bowel syndrome 147.89 9.78 66 244472 82346 63162138
Epstein-Barr virus infection 145.24 9.78 167 244371 7883 63236601
Hospitalisation 145.22 9.78 73 244465 85008 63159476
Hand deformity 144.29 9.78 245 244293 159212 63085272
Cushingoid 143.05 9.78 170 244368 8315 63236169
Cytomegalovirus infection reactivation 142.73 9.78 120 244418 3843 63240641
Nocardiosis 142.42 9.78 91 244447 1885 63242599
Wrong technique in product usage process 139.74 9.78 34 244504 62306 63182178
Respiratory failure 139.14 9.78 766 243772 101092 63143392
Klebsiella infection 138.48 9.78 168 244370 8398 63236086
Steroid diabetes 138.01 9.78 77 244461 1231 63243253
Blood urine present 137.96 9.78 225 244313 14844 63229640
Mucormycosis 137.93 9.78 103 244435 2768 63241716
Progressive multifocal leukoencephalopathy 137.26 9.78 207 244331 12764 63231720
Delayed graft function 136.64 9.78 72 244466 1021 63243463
Lymphocyte percentage decreased 134.36 9.78 103 244435 2882 63241602
Acute graft versus host disease in skin 133.64 9.78 109 244429 3343 63241141
Graft versus host disease 133.46 9.78 147 244391 6616 63237868
Drug intolerance 132.89 9.78 674 243864 307987 62936497
Multiple sclerosis relapse 132.70 9.78 450 244088 48028 63196456
Neutrophil percentage increased 131.26 9.78 101 244437 2842 63241642
Graft versus host disease in gastrointestinal tract 131.11 9.78 105 244433 3136 63241348
Muscle injury 131.04 9.78 44 244494 65301 63179183
Ear pruritus 130.45 9.78 114 244424 3851 63240633
Discomfort 128.95 9.78 283 244255 167091 63077393
Enterococcal infection 128.63 9.78 155 244383 7693 63236791
Urine analysis abnormal 124.02 9.78 123 244415 4893 63239591
Diarrhoea 123.31 9.78 1977 242561 713389 62531095
Injection site erythema 121.37 9.78 86 244452 83088 63161396
Graft versus host disease in skin 119.40 9.78 95 244443 2810 63241674
Device expulsion 116.48 9.78 4 244534 34918 63209566
Pneumomediastinum 115.75 9.78 71 244467 1365 63243119
Acute respiratory distress syndrome 115.41 9.78 270 244268 23264 63221220
Pericarditis 114.64 9.78 207 244331 131372 63113112
Pseudomonas infection 114.49 9.78 176 244362 11037 63233447
Red cell distribution width increased 112.86 9.78 169 244369 10355 63234129
Sleep disorder due to general medical condition, insomnia type 112.21 9.78 31 244507 52186 63192298
Varicella zoster virus infection 106.40 9.78 86 244452 2603 63241881
Suicide attempt 104.35 9.78 52 244486 60866 63183618
COVID-19 103.31 9.78 768 243770 112335 63132149
Human herpesvirus 6 infection 101.29 9.78 87 244451 2870 63241614
Bacterial test positive 100.67 9.78 113 244425 5194 63239290
Peripheral swelling 99.01 9.78 609 243929 265333 62979151
Dehydration 98.46 9.78 340 244198 173014 63071470
Cardiac failure congestive 98.22 9.78 127 244411 92306 63152178
Chest discomfort 96.65 9.78 740 243798 109229 63135255
Folliculitis 95.82 9.78 78 244460 70239 63174245
Immunodeficiency 95.66 9.78 229 244309 20025 63224459
Temperature regulation disorder 95.46 9.78 118 244420 6014 63238470
Bacterial test 94.52 9.78 58 244480 1116 63243368
Acute graft versus host disease in intestine 93.65 9.78 67 244471 1682 63242802
Pneumatosis intestinalis 93.01 9.78 76 244462 2337 63242147
Septic shock 92.25 9.78 503 244035 66126 63178358
Blood pressure diastolic increased 91.01 9.78 149 244389 9861 63234623
Stomatitis 90.85 9.78 255 244283 138470 63106014
Urine ketone body present 90.57 9.78 76 244462 2427 63242057
Acinetobacter infection 90.23 9.78 63 244475 1520 63242964
Pain 90.07 9.78 2170 242368 738458 62506026
Multiple sclerosis 88.80 9.78 250 244288 24122 63220362
Overdose 88.25 9.78 195 244343 114883 63129601
Fatigue 87.03 9.78 2683 241855 885345 62359139
Loss of personal independence in daily activities 84.78 9.78 153 244385 97137 63147347
Pyrexia 84.63 9.78 2391 242147 468087 62776397
Vomiting 84.49 9.78 1583 242955 558034 62686450
Respiratory rate increased 84.49 9.78 172 244366 13476 63231008
Escherichia infection 84.07 9.78 165 244373 12589 63231895
Osteonecrosis 82.98 9.78 245 244293 24285 63220199
Haemoglobin urine present 82.91 9.78 47 244491 776 63243708
Feeling hot 82.86 9.78 399 244139 49955 63194529
Adenovirus infection 81.76 9.78 84 244454 3487 63240997
Liver transplant rejection 81.54 9.78 57 244481 1378 63243106
Serotonin syndrome 81.49 9.78 8 244530 28674 63215810
Neutrophil count increased 81.46 9.78 190 244348 16337 63228147
Culture urine positive 81.31 9.78 85 244453 3602 63240882
Substance-induced psychotic disorder 80.61 9.78 64 244474 1887 63242597
Accidental exposure to product 79.58 9.78 7 244531 27398 63217086
Lower respiratory tract infection 79.58 9.78 253 244285 132054 63112430
Immunosuppressant drug level increased 76.90 9.78 82 244456 3556 63240928
Electric shock 76.33 9.78 53 244485 1267 63243217
Cytomegalovirus colitis 75.64 9.78 67 244471 2305 63242179
Injection site swelling 75.09 9.78 45 244493 47527 63196957
Reversible cerebral vasoconstriction syndrome 74.81 9.78 70 244468 2588 63241896
Rheumatoid factor positive 74.20 9.78 132 244406 84274 63160210
Protein urine present 73.96 9.78 104 244434 6016 63238468
Hypertension 73.78 9.78 1497 243041 277806 62966678
Hyponatraemia 73.77 9.78 205 244333 111695 63132789
Gastrointestinal disorder 73.42 9.78 259 244279 130980 63113504
Orthostatic hypotension 73.10 9.78 24 244514 36136 63208348
Disseminated intravascular coagulation 72.95 9.78 199 244339 18852 63225632
Myocardial infarction 72.77 9.78 174 244364 99719 63144765
Pharyngeal paraesthesia 72.69 9.78 61 244477 1948 63242536
Oedema peripheral 70.47 9.78 434 244104 189077 63055407
Intervertebral discitis 70.44 9.78 74 244464 3154 63241330
Anti-cyclic citrullinated peptide antibody positive 70.04 9.78 222 244316 115990 63128494
Sedation 69.74 9.78 31 244507 38778 63205706
Disease recurrence 69.61 9.78 252 244286 27778 63216706
Duodenal ulcer perforation 69.16 9.78 145 244393 87064 63157420
Nausea 68.90 9.78 2645 241893 851826 62392658
Herpes simplex 68.38 9.78 118 244420 8153 63236331
Strongyloidiasis 67.27 9.78 48 244490 1200 63243284
Myopathy 66.87 9.78 139 244399 11052 63233432
Premature delivery 66.72 9.78 262 244276 30019 63214465
Injection site pruritus 66.67 9.78 46 244492 45070 63199414
Specific gravity urine decreased 66.47 9.78 40 244498 742 63243742
Sepsis 66.18 9.78 890 243648 152233 63092251
Pneumonia cytomegaloviral 65.60 9.78 60 244478 2154 63242330
Rebound effect 65.53 9.78 84 244454 4442 63240042
Coeliac disease 65.14 9.78 149 244389 12648 63231836
Viral haemorrhagic cystitis 65.08 9.78 41 244497 828 63243656
Pulmonary alveolar haemorrhage 65.03 9.78 85 244453 4583 63239901
Hypoglycaemia 64.34 9.78 82 244456 59983 63184501
Acute graft versus host disease 63.83 9.78 82 244456 4346 63240138
Lupus nephritis 63.59 9.78 66 244472 2773 63241711
Enterobacter infection 63.36 9.78 59 244479 2168 63242316
Leukopenia 62.88 9.78 511 244027 76779 63167705
Candida infection 62.22 9.78 245 244293 28106 63216378
Monocyte count increased 62.08 9.78 107 244431 7386 63237098
C-reactive protein increased 61.99 9.78 597 243941 94110 63150374
Epstein-Barr virus associated lymphoproliferative disorder 61.40 9.78 54 244484 1840 63242644
Chorioretinopathy 61.37 9.78 39 244499 800 63243684
Pleocytosis 61.11 9.78 39 244499 806 63243678
Drug ineffective 60.45 9.78 4735 239803 1040030 62204454
Infective aneurysm 59.98 9.78 30 244508 379 63244105
Cytomegalovirus chorioretinitis 59.89 9.78 52 244486 1741 63242743
Therapy interrupted 59.79 9.78 25 244513 32430 63212054
Intentional self-injury 59.57 9.78 13 244525 25674 63218810
Staphylococcal sepsis 59.55 9.78 110 244428 8018 63236466
Intentional product use issue 59.29 9.78 753 243785 127139 63117345
Hypogammaglobulinaemia 59.05 9.78 102 244436 7053 63237431
Thrombocytopenia 58.64 9.78 862 243676 150295 63094189
Food allergy 58.31 9.78 133 244405 11268 63233216
Knee arthroplasty 58.07 9.78 74 244464 54132 63190352
Drug resistance 57.65 9.78 207 244331 22726 63221758
Impaired healing 57.59 9.78 202 244336 102340 63142144
Nitrite urine present 57.46 9.78 41 244497 1025 63243459
Cystitis haemorrhagic 57.32 9.78 75 244463 4048 63240436
Cytokine release syndrome 57.30 9.78 152 244386 14162 63230322
Osteonecrosis of jaw 57.17 9.78 32 244506 35091 63209393
Ureaplasma infection 57.15 9.78 34 244504 617 63243867
Contusion 57.14 9.78 341 244197 149703 63094781
Body temperature decreased 56.81 9.78 190 244348 20129 63224355
Human herpesvirus 8 infection 56.62 9.78 25 244513 233 63244251
Product quality issue 56.50 9.78 34 244504 35831 63208653
Acute graft versus host disease in liver 56.20 9.78 34 244504 637 63243847
COVID-19 pneumonia 55.99 9.78 150 244388 14059 63230425
Infection reactivation 55.34 9.78 42 244496 1157 63243327
Decreased appetite 55.09 9.78 660 243878 250392 62994092
Helicobacter infection 54.68 9.78 179 244359 92606 63151878
Systemic candida 54.67 9.78 65 244473 3180 63241304
Malignant neoplasm progression 54.45 9.78 150 244388 81971 63162513
Drug effective for unapproved indication 54.41 9.78 66 244472 3298 63241186
Status epilepticus 54.27 9.78 155 244383 15078 63229406
Vasculitis 54.26 9.78 174 244364 18035 63226449
Intra-abdominal pressure increased 54.24 9.78 24 244514 225 63244259
Injection site bruising 54.03 9.78 49 244489 41861 63202623
Therapy cessation 53.68 9.78 25 244513 30432 63214052
Red blood cells urine 53.53 9.78 31 244507 534 63243950
Pulmonary mucormycosis 53.52 9.78 26 244512 307 63244177
Polyomavirus viraemia 53.39 9.78 34 244504 700 63243784
Rheumatoid arthritis 53.31 9.78 1317 243221 252502 62991982
Systemic mycosis 53.21 9.78 41 244497 1156 63243328
Syncope 52.91 9.78 252 244286 117133 63127351
Immune thrombocytopenia 52.73 9.78 122 244416 10434 63234050
Serum sickness 52.72 9.78 60 244478 2800 63241684
Oral pruritus 52.65 9.78 54 244484 2237 63242247
Central nervous system viral infection 52.54 9.78 19 244519 98 63244386
Blood thyroid stimulating hormone decreased 52.52 9.78 76 244462 4514 63239970
Monocyte percentage increased 52.52 9.78 40 244498 1108 63243376
JC virus infection 52.02 9.78 51 244487 2000 63242484
Depressed level of consciousness 51.10 9.78 101 244437 61977 63182507
Blood calcium decreased 50.99 9.78 19 244519 26432 63218052
Therapeutic product effect decreased 50.79 9.78 487 244051 192700 63051784
Bacteraemia 50.09 9.78 164 244374 17184 63227300
Febrile bone marrow aplasia 49.78 9.78 96 244442 7229 63237255
Accidental overdose 49.77 9.78 14 244524 23295 63221189
Drug interaction 49.64 9.78 604 243934 228527 63015957
Adverse drug reaction 48.92 9.78 151 244387 79563 63164921
Thyroxine free increased 47.65 9.78 34 244504 850 63243634
Constipation 47.58 9.78 596 243942 224347 63020137
Dizziness 47.14 9.78 1278 243260 428647 62815837
Stenotrophomonas infection 46.99 9.78 48 244490 1979 63242505
Poor venous access 46.55 9.78 144 244394 14641 63229843
Surgery 46.28 9.78 42 244496 35870 63208614
Anaphylactic shock 46.14 9.78 197 244341 23436 63221048
International normalised ratio increased 46.07 9.78 67 244471 46358 63198126
Granulomatosis with polyangiitis 46.03 9.78 50 244488 2215 63242269
Psoriatic arthropathy 45.75 9.78 189 244349 91331 63153153
Intensive care unit acquired weakness 45.23 9.78 32 244506 789 63243695
Demyelination 44.97 9.78 89 244449 6831 63237653
Cerebrovascular accident 44.64 9.78 239 244299 107785 63136699
Toxoplasmosis 44.59 9.78 41 244497 1482 63243002
Diffuse large B-cell lymphoma 44.44 9.78 87 244451 6625 63237859
Pedal pulse abnormal 44.40 9.78 19 244519 163 63244321
Chronic graft versus host disease 44.02 9.78 57 244481 3045 63241439
Tachycardia 43.94 9.78 669 243869 117487 63126997
Red blood cell sedimentation rate abnormal 43.91 9.78 11 244527 19771 63224713
Encephalitis 43.66 9.78 102 244436 8778 63235706
Systemic inflammatory response syndrome 43.63 9.78 78 244460 5543 63238941
Device malfunction 43.58 9.78 8 244530 17849 63226635
Nephropathy toxic 43.50 9.78 106 244432 9373 63235111
Brain abscess 43.47 9.78 47 244491 2071 63242413
Memory impairment 43.45 9.78 230 244308 104028 63140456
Hypercholesterolaemia 43.34 9.78 180 244358 21154 63223330
Rhabdomyolysis 43.05 9.78 64 244474 43887 63200597
Human bocavirus infection 42.72 9.78 24 244514 389 63244095
Device issue 42.72 9.78 19 244519 23762 63220722
Blister 42.36 9.78 309 244229 129505 63114979
Full blood count decreased 41.94 9.78 24 244514 26000 63218484
Segmental diverticular colitis 41.90 9.78 18 244520 156 63244328
Rash erythematous 41.86 9.78 294 244244 42216 63202268
Sedation complication 41.61 9.78 3 244535 13819 63230665
Optic neuritis 41.60 9.78 97 244441 8338 63236146
C-reactive protein abnormal 41.49 9.78 71 244467 46025 63198459
Rash 40.99 9.78 1755 242783 559116 62685368
Proteinuria 40.85 9.78 164 244374 18981 63225503
Listeriosis 40.79 9.78 39 244499 1482 63243002
West Nile viral infection 40.66 9.78 23 244515 378 63244106
Psoriasis 40.17 9.78 185 244353 86772 63157712
Transient ischaemic attack 39.96 9.78 52 244486 37701 63206783
Full blood count abnormal 39.80 9.78 38 244500 31679 63212805
Disseminated tuberculosis 39.62 9.78 52 244486 2815 63241669
Product use issue 39.58 9.78 604 243934 219916 63024568
Cerebral aspergillosis 39.57 9.78 23 244515 399 63244085
General physical health deterioration 39.52 9.78 542 243996 200860 63043624
Red blood cell count increased 39.27 9.78 54 244484 3058 63241426
Hypofibrinogenaemia 39.22 9.78 34 244504 1136 63243348
Suicidal ideation 39.19 9.78 117 244421 62304 63182180
Nephrotic syndrome 39.03 9.78 74 244464 5502 63238982
Partial seizures 39.01 9.78 76 244462 5766 63238718
Pneumatosis 38.92 9.78 23 244515 412 63244072
Hypophagia 38.59 9.78 38 244500 31221 63213263
Encephalitis cytomegalovirus 38.37 9.78 25 244513 536 63243948
Central nervous system infection 38.29 9.78 28 244510 728 63243756
Candida sepsis 38.18 9.78 36 244502 1344 63243140
CSF oligoclonal band present 38.04 9.78 22 244516 378 63244106
Mycoplasma infection 37.86 9.78 24 244514 490 63243994
Blood immunoglobulin M decreased 37.83 9.78 31 244507 957 63243527
Feeding intolerance 37.70 9.78 28 244510 746 63243738
Calcium ionised decreased 37.62 9.78 20 244518 289 63244195
Colitis ulcerative 37.47 9.78 199 244339 25892 63218592
Necrotising herpetic retinopathy 37.25 9.78 14 244524 82 63244402
Adrenal insufficiency 37.06 9.78 152 244386 17763 63226721
Bone pain 36.82 9.78 99 244439 54542 63189942
Herpes zoster 36.71 9.78 482 244056 81980 63162504
Pregnancy 36.71 9.78 53 244485 36783 63207701
Injection site reaction 36.52 9.78 110 244428 58414 63186070
Granulocyte count increased 36.41 9.78 29 244509 859 63243625
Hip arthroplasty 36.29 9.78 81 244457 47565 63196919
Oral herpes 36.18 9.78 197 244341 25877 63218607
Hepatocellular injury 36.08 9.78 204 244334 27177 63217307
Gastrooesophageal reflux disease 36.06 9.78 218 244320 95421 63149063
Hyperglycaemia 35.79 9.78 280 244258 41587 63202897
Sleep disorder due to a general medical condition 35.70 9.78 3 244535 12185 63232299
Plasma cell myeloma 35.45 9.78 52 244486 35853 63208631
Mean cell haemoglobin decreased 35.35 9.78 68 244470 5111 63239373
Urticaria 35.28 9.78 862 243676 164940 63079544
Device difficult to use 35.25 9.78 4 244534 12792 63231692
Neuroleptic malignant syndrome 35.22 9.78 3 244535 12053 63232431
Glomerulonephritis 35.19 9.78 39 244499 1767 63242717
Cells in urine 35.13 9.78 17 244521 199 63244285
Hepatitis 35.07 9.78 268 244270 39520 63204964
Abdominal pain upper 34.84 9.78 572 243966 205872 63038612
Graft versus host disease in liver 34.79 9.78 25 244513 632 63243852
Cough 34.73 9.78 1418 243120 291325 62953159
Chronic allograft nephropathy 34.71 9.78 26 244512 702 63243782
Mycobacterium abscessus infection 34.56 9.78 25 244513 639 63243845
Sleep disorder 34.51 9.78 179 244359 81387 63163097
Incorrect dose administered 34.43 9.78 117 244421 59851 63184633
Secondary immunodeficiency 34.35 9.78 34 244504 1349 63243135
Unresponsive to stimuli 34.35 9.78 48 244490 33768 63210716
Blood pressure systolic decreased 34.25 9.78 83 244455 7314 63237170
Aplasia 34.22 9.78 60 244478 4199 63240285
Joint swelling 34.08 9.78 981 243557 326685 62917799
Cytomegalovirus enterocolitis 33.99 9.78 25 244513 656 63243828
Haemolytic uraemic syndrome 33.97 9.78 45 244493 2458 63242026
Throat tightness 33.84 9.78 187 244351 24700 63219784
Dermatomyositis 33.82 9.78 48 244490 2800 63241684
Poisoning 33.73 9.78 6 244532 13694 63230790
Scedosporium infection 33.48 9.78 23 244515 540 63243944
Laryngeal stenosis 33.48 9.78 30 244508 1048 63243436
Injection site mass 33.36 9.78 15 244523 18641 63225843
Urine leukocyte esterase 33.32 9.78 15 244523 147 63244337
Herpes virus infection 33.18 9.78 69 244469 5487 63238997
Haemolytic anaemia 33.17 9.78 100 244438 10025 63234459
Breast cancer 33.10 9.78 87 244451 48296 63196188
Medication error 32.82 9.78 98 244440 52186 63192298
Injection site warmth 32.68 9.78 9 244529 15186 63229298
Intestinal perforation 32.68 9.78 111 244427 11852 63232632
Epstein-Barr virus infection reactivation 32.59 9.78 26 244512 772 63243712
Gastroenteritis norovirus 32.52 9.78 40 244498 2028 63242456
Rhinocerebral mucormycosis 32.49 9.78 21 244517 444 63244040
Immunosuppressant drug level decreased 32.31 9.78 28 244510 935 63243549
Pulmonary nocardiosis 32.27 9.78 19 244519 338 63244146
Cataract 32.23 9.78 349 244189 56704 63187780
Intentional product misuse 32.22 9.78 123 244415 60794 63183690
Product storage error 31.90 9.78 9 244529 14947 63229537
Temperature intolerance 31.72 9.78 91 244447 8873 63235611
Urinary casts 31.69 9.78 25 244513 730 63243754
Symptom masked 31.58 9.78 25 244513 734 63243750
Hepatic function abnormal 31.53 9.78 248 244290 36894 63207590
Quadriparesis 31.51 9.78 39 244499 1990 63242494
Renal transplant failure 31.49 9.78 25 244513 737 63243747
Bronchospasm 31.42 9.78 141 244397 17139 63227345
Oropharyngeal pain 31.36 9.78 525 244013 93962 63150522
Parvovirus B19 infection 31.32 9.78 22 244516 536 63243948
Haemoglobin urine 31.21 9.78 14 244524 136 63244348
Device dislocation 30.87 9.78 32 244506 25673 63218811
Macular degeneration 30.83 9.78 29 244509 24347 63220137
Engraftment syndrome 30.80 9.78 21 244517 487 63243997
Injection site haemorrhage 30.66 9.78 29 244509 24285 63220199
Multiple-drug resistance 30.64 9.78 64 244474 5106 63239378
Band sensation 30.54 9.78 26 244512 847 63243637
Hypertransaminasaemia 30.43 9.78 74 244464 6535 63237949
Unevaluable event 30.36 9.78 99 244439 51287 63193197
Myelitis 30.32 9.78 32 244506 1371 63243113
Viraemia 30.21 9.78 31 244507 1285 63243199
Product prescribing error 30.16 9.78 34 244504 26255 63218229
Therapy partial responder 30.09 9.78 100 244438 10558 63233926
Glomerulosclerosis 30.06 9.78 19 244519 386 63244098
Underdose 29.90 9.78 37 244501 27419 63217065
Acute myeloid leukaemia recurrent 29.84 9.78 34 244504 1589 63242895
Perinephric abscess 29.68 9.78 15 244523 194 63244290
Lethargy 29.68 9.78 113 244425 55894 63188590
Breast cancer female 29.22 9.78 8 244530 13551 63230933
Alveolitis 28.70 9.78 45 244493 2870 63241614
Aphthous ulcer 28.63 9.78 118 244420 13820 63230664
Diabetes mellitus 28.62 9.78 335 244203 55475 63189009
Vaginal flatulence 28.57 9.78 48 244490 3245 63241239
Central nervous system lymphoma 28.52 9.78 32 244506 1470 63243014
Pulmonary haemorrhage 28.48 9.78 76 244462 7105 63237379
Herpes simplex colitis 28.47 9.78 8 244530 14 63244470
Type I hypersensitivity 28.39 9.78 45 244493 2897 63241587
Smear cervix abnormal 28.35 9.78 45 244493 2901 63241583
Thunderclap headache 28.26 9.78 15 244523 216 63244268
Pyelonephritis fungal 28.22 9.78 13 244525 135 63244349
Oral candidiasis 28.17 9.78 167 244371 22631 63221853
Pancytopenia 28.05 9.78 527 244011 96406 63148078
Injection site rash 28.02 9.78 19 244519 18790 63225694
Therapy non-responder 27.91 9.78 429 244109 75472 63169012
Aspergillosis oral 27.91 9.78 10 244528 50 63244434
Oedema 27.85 9.78 241 244297 97381 63147103
Urinary tract candidiasis 27.81 9.78 21 244517 574 63243910
Shock 27.80 9.78 170 244368 23293 63221191
Nightmare 27.79 9.78 20 244518 19174 63225310
Arterial occlusive disease 27.74 9.78 67 244471 5891 63238593
Gastroenteritis rotavirus 27.73 9.78 13 244525 141 63244343
Staphylococcal bacteraemia 27.72 9.78 64 244474 5466 63239018
Swollen joint count increased 27.70 9.78 61 244477 35993 63208491
Pain in extremity 27.66 9.78 1021 243517 330465 62914019
Interstitial lung disease 27.61 9.78 362 244176 61546 63182938
Adverse event 27.61 9.78 150 244388 67409 63177075
Muscle spasms 27.55 9.78 429 244109 155721 63088763
Infection 27.52 9.78 672 243866 228501 63015983
Choroiditis 27.50 9.78 14 244524 184 63244300
Injection site urticaria 27.31 9.78 10 244528 14063 63230421
Band neutrophil percentage increased 27.26 9.78 15 244523 233 63244251
Coronary artery disease 27.23 9.78 52 244486 32325 63212159
Shock haemorrhagic 27.19 9.78 92 244446 9803 63234681
Dural arteriovenous fistula 27.15 9.78 8 244530 18 63244466
Encephalitis autoimmune 27.10 9.78 31 244507 1455 63243029
Coordination abnormal 27.03 9.78 115 244423 13658 63230826
Acute kidney injury 27.03 9.78 790 243748 262625 62981859
Bacillus infection 27.01 9.78 24 244514 829 63243655
Blood immunoglobulin A increased 26.87 9.78 23 244515 755 63243729
Respiratory distress 26.81 9.78 223 244315 33728 63210756
Needle issue 26.76 9.78 4 244534 10372 63234112
Engraft failure 26.74 9.78 17 244521 349 63244135
Pharyngeal dyskinesia 26.72 9.78 9 244529 36 63244448
Proteus infection 26.67 9.78 27 244511 1101 63243383
Monocyte count decreased 26.63 9.78 37 244501 2116 63242368
Hepatic enzyme increased 26.61 9.78 585 243953 201743 63042741
Neuralgia 26.52 9.78 181 244357 25745 63218739
Loss of consciousness 26.46 9.78 309 244229 117812 63126672
Listeria encephalitis 26.39 9.78 15 244523 249 63244235
Drug hypersensitivity 26.35 9.78 955 243583 309732 62934752
Liver function test abnormal 26.32 9.78 96 244442 48085 63196399
Sinusitis 26.30 9.78 668 243870 225985 63018499
Pain in jaw 26.25 9.78 83 244455 43413 63201071
Specific gravity urine increased 26.11 9.78 14 244524 206 63244278
Right ventricular failure 26.10 9.78 17 244521 17171 63227313
Neuropathy peripheral 25.99 9.78 296 244242 113371 63131113
Meningomyelitis herpes 25.97 9.78 9 244529 40 63244444
Staphylococcal infection 25.97 9.78 258 244280 40998 63203486
Natural killer-cell leukaemia 25.94 9.78 11 244527 92 63244392
Atypical haemolytic uraemic syndrome 25.94 9.78 22 244516 713 63243771
Bacterial sepsis 25.83 9.78 51 244487 3907 63240577
Tri-iodothyronine free increased 25.76 9.78 14 244524 212 63244272
CSF protein increased 25.72 9.78 19 244519 502 63243982
B-lymphocyte count decreased 25.53 9.78 26 244512 1068 63243416
Transplant failure 25.48 9.78 31 244507 1554 63242930
Pneumocystis jirovecii infection 25.46 9.78 30 244508 1454 63243030
Blood thyroid stimulating hormone increased 25.43 9.78 73 244465 7121 63237363
Mean cell haemoglobin concentration increased 25.40 9.78 19 244519 512 63243972
Renal vein thrombosis 25.28 9.78 17 244521 385 63244099
Pulmonary hypertension 25.21 9.78 67 244471 37056 63207428
Chronic graft versus host disease in liver 25.18 9.78 15 244523 273 63244211
Escherichia sepsis 25.15 9.78 58 244480 4949 63239535
Opportunistic infection 25.14 9.78 34 244504 1895 63242589
Proctitis 25.13 9.78 61 244477 5380 63239104
Torsade de pointes 25.05 9.78 10 244528 13341 63231143
Cytomegalovirus enteritis 25.03 9.78 15 244523 276 63244208
Product complaint 25.03 9.78 9 244529 12800 63231684
Steroid withdrawal syndrome 24.96 9.78 19 244519 526 63243958
Body temperature fluctuation 24.94 9.78 37 244501 2248 63242236
Necrotising retinitis 24.90 9.78 17 244521 395 63244089
Lip pruritus 24.87 9.78 24 244514 923 63243561
Cerebral artery stenosis 24.81 9.78 18 244520 462 63244022
Drug level decreased 24.81 9.78 77 244461 7842 63236642
Coma 24.63 9.78 146 244392 64218 63180266
Drug-induced liver injury 24.58 9.78 250 244288 39972 63204512
Urobilinogen urine increased 24.52 9.78 15 244523 287 63244197
Malignant catatonia 24.51 9.78 13 244525 187 63244297
Gangrene 24.49 9.78 65 244473 6058 63238426
Pyelonephritis 24.45 9.78 134 244404 17644 63226840
Bacterial vulvovaginitis 24.42 9.78 22 244516 774 63243710
Blood albumin increased 24.40 9.78 24 244514 945 63243539
Anorectal ulcer 24.34 9.78 9 244529 50 63244434
Drug tolerance decreased 24.28 9.78 19 244519 17454 63227030
Leukoencephalopathy 24.27 9.78 53 244485 4360 63240124
Anti-thyroid antibody positive 24.24 9.78 17 244521 413 63244071
Cytomegalovirus gastrointestinal infection 24.16 9.78 15 244523 295 63244189
Treatment noncompliance 24.12 9.78 69 244469 37256 63207228
Enterococcus test positive 24.02 9.78 26 244512 1147 63243337
Aspartate aminotransferase 24.00 9.78 17 244521 420 63244064
Post cholecystectomy syndrome 23.93 9.78 17 244521 422 63244062
Non-consummation 23.90 9.78 9 244529 53 63244431
Quadriplegia 23.88 9.78 32 244506 1768 63242716
Factor XIII deficiency 23.86 9.78 10 244528 81 63244403
Joint tuberculosis 23.82 9.78 11 244527 115 63244369
White blood cell count increased 23.81 9.78 289 244249 48272 63196212
Paralysis 23.73 9.78 88 244450 9812 63234672
Epstein-Barr virus associated lymphoma 23.59 9.78 18 244520 500 63243984
Diffuse alveolar damage 23.58 9.78 23 244515 896 63243588
Escherichia urinary tract infection 23.57 9.78 100 244438 11862 63232622
Chronic graft versus host disease in skin 23.48 9.78 21 244517 732 63243752
Sleep apnoea syndrome 23.46 9.78 48 244490 29085 63215399
Sense of oppression 23.44 9.78 24 244514 992 63243492
Chills 23.37 9.78 587 243951 112791 63131693
Mean cell volume decreased 23.29 9.78 49 244489 3929 63240555
Hepatic infarction 23.28 9.78 20 244518 660 63243824
Malacoplakia vesicae 23.22 9.78 9 244529 58 63244426
Eosinophil percentage increased 23.19 9.78 24 244514 1005 63243479
Central obesity 23.16 9.78 26 244512 1195 63243289
Faecal volume decreased 23.10 9.78 12 244526 165 63244319
Neuromyelitis optica spectrum disorder 23.09 9.78 24 244514 1010 63243474
Necrosis ischaemic 22.97 9.78 22 244516 838 63243646
Blood immunoglobulin G decreased 22.90 9.78 37 244501 2421 63242063
Atrial fibrillation 22.81 9.78 314 244224 116322 63128162
Leukocyturia 22.74 9.78 28 244510 1421 63243063
Cestode infection 22.65 9.78 14 244524 273 63244211
Rubella antibody positive 22.60 9.78 9 244529 63 63244421
Drug withdrawal syndrome 22.59 9.78 44 244494 27150 63217334
Tardive dyskinesia 22.58 9.78 3 244535 8499 63235985
Cryptococcosis 22.57 9.78 25 244513 1132 63243352
Orbital apex syndrome 22.49 9.78 8 244530 39 63244445
Corynebacterium infection 22.38 9.78 18 244520 541 63243943
Cerebellar stroke 22.34 9.78 14 244524 280 63244204
Blood creatinine decreased 22.31 9.78 59 244479 5486 63238998
Post-traumatic stress disorder 22.29 9.78 57 244481 5194 63239290
Hallucination 22.24 9.78 122 244416 54695 63189789
Mitochondrial DNA mutation 22.22 9.78 16 244522 406 63244078
Glomerular filtration rate increased 22.16 9.78 22 244516 876 63243608
Inappropriate schedule of product administration 22.13 9.78 275 244263 103690 63140794
Labelled drug-drug interaction medication error 22.11 9.78 12 244526 13387 63231097
Heart rate irregular 22.03 9.78 155 244383 22266 63222218
Angiosarcoma metastatic 22.01 9.78 9 244529 68 63244416
Neuropsychiatric lupus 22.01 9.78 12 244526 183 63244301
Multiple allergies 21.86 9.78 13 244525 13789 63230695
Abscess 21.83 9.78 124 244414 16544 63227940
Anaphylactic reaction 21.83 9.78 367 244171 65733 63178751
Pneumonia bacterial 21.75 9.78 83 244455 9382 63235102
Creatinine urine decreased 21.72 9.78 12 244526 188 63244296
Acute pulmonary oedema 21.68 9.78 75 244463 8083 63236401
Magnetic resonance imaging abnormal 21.66 9.78 41 244497 3044 63241440
Myelopathy 21.66 9.78 39 244499 2787 63241697
Muscular weakness 21.65 9.78 621 243917 121732 63122752
Metastases to liver 21.65 9.78 36 244502 23603 63220881
Muir-Torre syndrome 21.62 9.78 7 244531 24 63244460
Q fever 21.52 9.78 11 244527 146 63244338
Ulcer 21.43 9.78 173 244365 25934 63218550
Swollen tongue 21.29 9.78 66 244472 34734 63209750
Sensory loss 21.28 9.78 87 244451 10151 63234333
Schizophrenia 21.21 9.78 6 244532 9946 63234538
Lower limb fracture 21.17 9.78 38 244500 24183 63220301
Urinary tract infection bacterial 21.12 9.78 55 244483 5067 63239417
Colitis microscopic 21.11 9.78 5 244533 9334 63235150
Tri-iodothyronine free decreased 21.09 9.78 14 244524 310 63244174
JC polyomavirus test positive 21.09 9.78 27 244511 1426 63243058
Renal tubular atrophy 21.01 9.78 20 244518 756 63243728
Diverticulum 20.89 9.78 10 244528 11981 63232503
Meningoencephalitis bacterial 20.85 9.78 9 244529 79 63244405
Disseminated varicella zoster vaccine virus infection 20.85 9.78 8 244530 50 63244434
Band neutrophil count increased 20.85 9.78 15 244523 380 63244104
Skin fissures 20.76 9.78 93 244445 11295 63233189
Enthesopathy 20.72 9.78 4 244534 8610 63235874
Arteriovenous fistula 20.70 9.78 13 244525 261 63244223
Venous thrombosis 20.59 9.78 53 244485 4849 63239635
Mean cell haemoglobin concentration decreased 20.58 9.78 44 244494 3568 63240916
Emphysematous pyelonephritis 20.57 9.78 13 244525 264 63244220
Meningoencephalitis viral 20.56 9.78 14 244524 324 63244160
Scleroderma renal crisis 20.48 9.78 14 244524 326 63244158
Thrombocytopenic purpura 20.43 9.78 26 244512 1365 63243119
Obstructive airways disorder 20.41 9.78 30 244508 20669 63223815
Hyperammonaemia 20.38 9.78 55 244483 5177 63239307
Body temperature increased 20.31 9.78 226 244312 36966 63207518
Amnesia 20.27 9.78 128 244410 55457 63189027
Type 1 diabetes mellitus 20.26 9.78 45 244493 3745 63240739
Metastases to bone 20.21 9.78 31 244507 20988 63223496
Rhesus antigen positive 20.16 9.78 10 244528 124 63244360
Granuloma skin 20.12 9.78 4 244534 8433 63236051
Ultrasound ovary abnormal 20.01 9.78 9 244529 88 63244396
Lichen sclerosus 19.99 9.78 23 244515 1086 63243398
CSF measles antibody positive 19.97 9.78 8 244530 57 63244427
Cytopenia 19.86 9.78 93 244445 11508 63232976
Herpes simplex oesophagitis 19.82 9.78 11 244527 174 63244310
Coronavirus infection 19.80 9.78 48 244490 4230 63240254
Asymptomatic bacteriuria 19.78 9.78 13 244525 283 63244201
Biloma 19.73 9.78 8 244530 59 63244425
Osteomyelitis fungal 19.65 9.78 6 244532 16 63244468
Cytomegalovirus hepatitis 19.55 9.78 14 244524 352 63244132
Finger deformity 19.54 9.78 70 244468 7675 63236809
Central nervous system lesion 19.50 9.78 87 244451 10548 63233936
Breast cancer metastatic 19.49 9.78 11 244527 12007 63232477
Myasthenia gravis crisis 19.47 9.78 16 244522 496 63243988
Central nervous system lupus 19.41 9.78 16 244522 498 63243986
Myelocyte count increased 19.41 9.78 14 244524 356 63244128
Vein collapse 19.41 9.78 22 244516 1022 63243462
Stress cardiomyopathy 19.40 9.78 80 244458 9370 63235114
Infective pulmonary exacerbation of cystic fibrosis 19.38 9.78 5 244533 8812 63235672
Haemorrhagic varicella syndrome 19.37 9.78 5 244533 5 63244479
Bone marrow failure 19.33 9.78 185 244353 29105 63215379
Hypoproteinaemia 19.31 9.78 31 244507 2018 63242466
Mean cell haemoglobin increased 19.30 9.78 38 244500 2905 63241579
Hypersensitivity 19.24 9.78 926 243612 291759 62952725
Suspected COVID-19 19.18 9.78 35 244503 2527 63241957
Birdshot chorioretinopathy 19.17 9.78 8 244530 64 63244420
Abortion spontaneous 19.16 9.78 105 244433 47090 63197394
Antinuclear antibody 19.09 9.78 16 244522 510 63243974
Cerebral venous thrombosis 19.03 9.78 31 244507 2043 63242441
Graft versus host disease in lung 19.01 9.78 14 244524 368 63244116
Vaginal discharge 18.99 9.78 78 244460 9120 63235364
Pathogen resistance 18.94 9.78 61 244477 6337 63238147
Blood parathyroid hormone decreased 18.93 9.78 7 244531 9784 63234700
Lung neoplasm malignant 18.83 9.78 29 244509 19604 63224880
Female genital tract fistula 18.80 9.78 68 244470 7491 63236993
Perforation 18.79 9.78 23 244515 1160 63243324
Hepatic cyst infection 18.77 9.78 9 244529 103 63244381
Dementia 18.77 9.78 27 244511 18767 63225717
Immunoglobulins decreased 18.74 9.78 24 244514 1268 63243216
Urine oxalate increased 18.72 9.78 12 244526 250 63244234
Dry throat 18.68 9.78 63 244475 6702 63237782
Neurosarcoidosis 18.67 9.78 11 244527 196 63244288
Biliary anastomosis complication 18.62 9.78 7 244531 41 63244443
Premenstrual syndrome 18.46 9.78 18 244520 701 63243783
Neurological decompensation 18.45 9.78 35 244503 2603 63241881
Immunosuppression 18.40 9.78 75 244463 8739 63235745
Clostridium difficile colitis 18.38 9.78 139 244399 20430 63224054
Hypokalaemia 18.37 9.78 285 244253 103519 63140965
Complication associated with device 18.36 9.78 23 244515 16955 63227529
Dysphagia 18.36 9.78 459 244079 88126 63156358
Butterfly rash 18.34 9.78 28 244510 1745 63242739
Myelocyte percentage increased 18.33 9.78 11 244527 203 63244281
Haemodynamic instability 18.24 9.78 77 244461 9113 63235371
Autoimmune hepatitis 18.23 9.78 73 244465 8437 63236047
Fungaemia 18.21 9.78 33 244505 2370 63242114
Immune effector cell-associated neurotoxicity syndrome 18.19 9.78 32 244506 2245 63242239
Sensitivity to weather change 18.19 9.78 3 244535 7234 63237250
Blood loss anaemia 18.15 9.78 6 244532 8995 63235489
Pulmonary tuberculosis 18.11 9.78 48 244490 4469 63240015
Disseminated varicella zoster virus infection 18.11 9.78 12 244526 265 63244219
Passenger lymphocyte syndrome 18.08 9.78 8 244530 75 63244409
Lung transplant rejection 18.03 9.78 20 244518 907 63243577
Kaposi's sarcoma 18.03 9.78 10 244528 158 63244326
Product substitution issue 18.01 9.78 21 244517 15975 63228509
Immune reconstitution inflammatory syndrome 18 9.78 58 244480 6026 63238458
Dystonia 18.00 9.78 16 244522 13803 63230681
Hypertriglyceridaemia 17.92 9.78 59 244479 6200 63238284
Mucous stools 17.91 9.78 46 244492 4202 63240282
Basal cell carcinoma 17.90 9.78 52 244486 27939 63216545
Anti-cyclic citrullinated peptide antibody 17.84 9.78 62 244476 6696 63237788
Gastropleural fistula 17.82 9.78 7 244531 47 63244437
Focal segmental glomerulosclerosis 17.82 9.78 25 244513 1443 63243041
Dysmenorrhoea 17.78 9.78 44 244494 3929 63240555
Fracture 17.78 9.78 30 244508 19554 63224930
Crystalluria 17.74 9.78 14 244524 409 63244075
Encephalopathy 17.71 9.78 227 244311 38393 63206091
Capillary leak syndrome 17.68 9.78 31 244507 2169 63242315
Hepatic necrosis 17.54 9.78 55 244483 5632 63238852
Cervicitis 17.51 9.78 15 244523 493 63243991
Injection site extravasation 17.49 9.78 74 244464 8767 63235717
Head injury 17.45 9.78 51 244487 27345 63217139
Gastrointestinal mucormycosis 17.42 9.78 11 244527 223 63244261
Malacoplakia 17.38 9.78 10 244528 170 63244314
Hemiparesis 17.37 9.78 151 244387 23131 63221353
Product dispensing error 17.34 9.78 9 244529 10296 63234188
Bilirubin urine present 17.29 9.78 8 244530 84 63244400
Allergy to chemicals 17.26 9.78 37 244501 3005 63241479
Intracranial infection 17.25 9.78 6 244532 27 63244457
Uterine perforation 17.25 9.78 3 244535 6960 63237524
Serratia infection 17.24 9.78 20 244518 953 63243531
Complications of transplant surgery 17.18 9.78 10 244528 174 63244310
SARS-CoV-2 test positive 17.18 9.78 69 244469 7987 63236497
Hypotension 17.16 9.78 1245 243293 271359 62973125
Klebsiella test positive 17.14 9.78 22 244516 1165 63243319
Pneumonia lipoid 17.12 9.78 9 244529 127 63244357
Asthenia 17.12 9.78 1259 243279 382345 62862139
Neoplasm progression 17.11 9.78 77 244461 36351 63208133
Thrombosis 17.10 9.78 163 244375 64592 63179892
Peritonitis 17.10 9.78 119 244419 17035 63227449
Sebaceous carcinoma 17.08 9.78 6 244532 28 63244456
Tuberculosis gastrointestinal 17.07 9.78 13 244525 360 63244124
Steroid dependence 17.05 9.78 27 244511 1737 63242747
Pyomyositis 17.01 9.78 13 244525 362 63244122
Dyspnoea 16.88 9.78 2261 242277 659052 62585432
Encephalitis brain stem 16.87 9.78 9 244529 131 63244353
Acute respiratory failure 16.80 9.78 205 244333 34280 63210204
Bronchiolitis obliterans syndrome 16.75 9.78 9 244529 133 63244351
Adrenal atrophy 16.74 9.78 6 244532 30 63244454
Blood brain barrier defect 16.73 9.78 8 244530 91 63244393
Hepatitis toxic 16.69 9.78 38 244500 3215 63241269
T-lymphocyte count decreased 16.68 9.78 12 244526 304 63244180
Osteoporosis 16.67 9.78 312 244226 57026 63187458
Paraesthesia ear 16.64 9.78 11 244527 242 63244242
Menstruation irregular 16.57 9.78 62 244476 6942 63237542
Microangiopathy 16.55 9.78 22 244516 1206 63243278
Papilloma viral infection 16.53 9.78 25 244513 1545 63242939
Liver abscess 16.53 9.78 35 244503 2819 63241665
Abnormal dreams 16.52 9.78 10 244528 10506 63233978
Flatulence 16.51 9.78 73 244465 34629 63209855
Ependymoma 16.46 9.78 7 244531 59 63244425
Chronic obstructive pulmonary disease 16.46 9.78 158 244380 62528 63181956
White blood cells urine 16.45 9.78 14 244524 456 63244028
Bacterial infection 16.44 9.78 130 244408 19369 63225115
Hysterectomy 16.43 9.78 8 244530 9491 63234993
Disseminated aspergillosis 16.36 9.78 8 244530 96 63244388
Escherichia bacteraemia 16.33 9.78 42 244496 3841 63240643
Mobility decreased 16.29 9.78 349 244189 120810 63123674
Acute myocardial infarction 16.26 9.78 66 244472 32058 63212426
Colitis 16.23 9.78 270 244268 48258 63196226
Joint effusion 16.22 9.78 117 244421 16943 63227541
pH urine increased 16.21 9.78 13 244525 389 63244095
Vaginal haemorrhage 16.20 9.78 53 244485 27434 63217050
Thyroid stimulating immunoglobulin 16.16 9.78 7 244531 62 63244422
Malacoplakia gastrointestinal 16.16 9.78 7 244531 62 63244422
Rash maculo-papular 16.15 9.78 191 244347 31705 63212779
Gastrointestinal mucosa hyperaemia 16.13 9.78 10 244528 196 63244288
Night sweats 16.01 9.78 116 244422 48698 63195786
Intestinal obstruction 15.95 9.78 63 244475 30836 63213648
Paraparesis 15.94 9.78 30 244508 2218 63242266
Haematocrit decreased 15.89 9.78 226 244312 39114 63205370
Hairy cell leukaemia 15.88 9.78 7 244531 65 63244419
Anal erythema 15.87 9.78 10 244528 202 63244282
Monoparesis 15.86 9.78 25 244513 1602 63242882
Rheumatoid factor 15.83 9.78 12 244526 330 63244154
Brain oedema 15.67 9.78 101 244437 14094 63230390
Electrocardiogram QT prolonged 15.65 9.78 150 244388 59380 63185104
Device leakage 15.65 9.78 4 244534 7092 63237392
Thrombotic thrombocytopenic purpura 15.62 9.78 41 244497 3795 63240689
Injection site induration 15.61 9.78 8 244530 9218 63235266
Mental status changes 15.59 9.78 89 244449 39510 63204974
Pneumonia klebsiella 15.58 9.78 31 244507 2388 63242096
Meningitis chemical 15.54 9.78 9 244529 155 63244329
Device breakage 15.47 9.78 13 244525 11529 63232955
Ureteral disorder 15.43 9.78 12 244526 343 63244141
Moyamoya disease 15.43 9.78 7 244531 70 63244414
CD4 lymphocytes decreased 15.42 9.78 23 244515 1404 63243080
Wheezing 15.41 9.78 267 244271 95328 63149156
Fungal infection 15.36 9.78 213 244325 36661 63207823
Adult T-cell lymphoma/leukaemia 15.32 9.78 10 244528 215 63244269
Multiple fractures 15.30 9.78 7 244531 8611 63235873
Chorioretinitis 15.26 9.78 15 244523 590 63243894
IgA nephropathy 15.26 9.78 15 244523 590 63243894
Hypomagnesaemia 15.21 9.78 58 244480 28679 63215805
Transient hypogammaglobulinaemia of infancy 15.19 9.78 6 244532 41 63244443
Blood gases abnormal 15.17 9.78 17 244521 780 63243704
Poikiloderma 15.16 9.78 10 244528 219 63244265
Gastroduodenal ulcer 15.10 9.78 9 244529 164 63244320
Rhodococcus infection 15.09 9.78 8 244530 115 63244369
Blindness cortical 15.07 9.78 14 244524 513 63243971
Growth retardation 15.05 9.78 22 244516 1319 63243165
Vascular rupture 15.04 9.78 25 244513 1675 63242809
Epstein-Barr viraemia 15.02 9.78 19 244519 991 63243493
Hepatic artery thrombosis 15.01 9.78 7 244531 75 63244409
Aeromonas infection 15.01 9.78 7 244531 75 63244409
Chronic graft versus host disease in eye 14.97 9.78 8 244530 117 63244367
Feeling abnormal 14.96 9.78 446 244092 147946 63096538
Sputum discoloured 14.87 9.78 25 244513 16322 63228162
Gait disturbance 14.85 9.78 566 243972 182612 63061872
Aortitis salmonella 14.85 9.78 5 244533 20 63244464
Pharyngeal disorder 14.83 9.78 27 244511 1946 63242538
Lymphocele 14.82 9.78 17 244521 800 63243684
Hepatic haemorrhage 14.80 9.78 14 244524 525 63243959
Femur fracture 14.79 9.78 97 244441 41659 63202825
Tenosynovitis stenosans 14.78 9.78 37 244501 3327 63241157
Thyroid stimulating immunoglobulin increased 14.77 9.78 7 244531 78 63244406
Scleritis 14.76 9.78 44 244494 4384 63240100
Encephalitis Japanese B 14.71 9.78 6 244532 45 63244439
Migraine 14.69 9.78 295 244243 103051 63141433
Bursitis 14.64 9.78 212 244326 36829 63207655
Hypertensive encephalopathy 14.59 9.78 15 244523 623 63243861
Pseudomonal sepsis 14.55 9.78 30 244508 2371 63242113
Lipaemic index score 14.53 9.78 7 244531 81 63244403
Diabetic macroangiopathy 14.50 9.78 8 244530 125 63244359
Fusarium infection 14.44 9.78 15 244523 631 63243853
Nail bed inflammation 14.39 9.78 12 244526 380 63244104
Normal newborn 14.38 9.78 67 244471 8274 63236210
Extrapyramidal disorder 14.36 9.78 18 244520 13266 63231218
Anaphylactoid reaction 14.36 9.78 39 244499 3684 63240800
Visceral leishmaniasis 14.28 9.78 14 244524 549 63243935
Dyskinesia 14.23 9.78 69 244469 31933 63212551
Delayed engraftment 14.22 9.78 8 244530 130 63244354
Pre-existing condition improved 14.17 9.78 7 244531 8237 63236247
Bacillus bacteraemia 14.17 9.78 7 244531 86 63244398
Breast cancer stage II 14.16 9.78 8 244530 8728 63235756
Oesophageal candidiasis 14.13 9.78 51 244487 5612 63238872
Lymphocyte count increased 14.12 9.78 37 244501 3421 63241063
Peripheral vascular disorder 14.10 9.78 3 244535 6032 63238452
Transfusion 14.10 9.78 23 244515 15194 63229290
Aspergilloma 14.08 9.78 10 244528 248 63244236
Product administration error 14.04 9.78 42 244496 22355 63222129
Sneezing 14.03 9.78 119 244419 18099 63226385
Parainfluenzae virus infection 14.02 9.78 29 244509 2298 63242186
Eye pruritus 14.01 9.78 32 244506 18639 63225845
Trichodysplasia spinulosa 13.99 9.78 14 244524 563 63243921
Limbic encephalitis 13.98 9.78 11 244527 320 63244164
Sinus bradycardia 13.95 9.78 100 244438 14451 63230033
Akathisia 13.95 9.78 9 244529 9137 63235347
Renal graft infection 13.94 9.78 10 244528 252 63244232
Panniculitis 13.87 9.78 14 244524 11371 63233113
Hypercalcaemia 13.83 9.78 59 244479 28263 63216221
Interleukin-2 receptor increased 13.82 9.78 7 244531 91 63244393
Excessive skin 13.80 9.78 8 244530 138 63244346
Prescribed underdose 13.80 9.78 63 244475 29626 63214858
Ankylosing spondylitis 13.79 9.78 12 244526 10462 63234022
Infected varicose vein 13.79 9.78 5 244533 26 63244458
Japanese spotted fever 13.79 9.78 5 244533 26 63244458
Polyglandular disorder 13.79 9.78 5 244533 26 63244458
Viral myelitis 13.79 9.78 5 244533 26 63244458
Product label confusion 13.78 9.78 25 244513 1797 63242687
Eosinophil count abnormal 13.77 9.78 14 244524 574 63243910
Globulins decreased 13.71 9.78 10 244528 259 63244225
Parathyroid hyperplasia 13.70 9.78 8 244530 140 63244344
Premature baby 13.70 9.78 131 244407 20604 63223880
H3N2 influenza 13.69 9.78 3 244535 0 63244484
Magnesium deficiency 13.69 9.78 14 244524 578 63243906
Obliterative bronchiolitis 13.68 9.78 27 244511 2068 63242416
Autoimmune thyroiditis 13.66 9.78 40 244498 3946 63240538
Complication of device insertion 13.65 9.78 6 244532 7558 63236926
Electric shock sensation 13.63 9.78 16 244522 772 63243712
Limb mass 13.63 9.78 35 244503 3197 63241287
Nodular regenerative hyperplasia 13.62 9.78 13 244525 493 63243991
Osteoarthritis 13.60 9.78 272 244266 95071 63149413
Breast cancer stage III 13.56 9.78 12 244526 10374 63234110
Rheumatoid factor increased 13.52 9.78 25 244513 1824 63242660
Pneumonia fungal 13.51 9.78 49 244489 5406 63239078
Beta 2 microglobulin increased 13.50 9.78 8 244530 144 63244340
Chronic graft versus host disease oral 13.50 9.78 8 244530 144 63244340
Ovarian fibroma 13.49 9.78 7 244531 96 63244388
Urogenital disorder 13.49 9.78 6 244532 57 63244427
Pneumonia cryptococcal 13.49 9.78 16 244522 781 63243703
Thyroxine free decreased 13.48 9.78 15 244523 683 63243801
Pancreas transplant rejection 13.46 9.78 8 244530 145 63244339
Renal tubular necrosis 13.41 9.78 85 244453 11793 63232691
Thymoma 13.38 9.78 9 244529 204 63244280
Cardiac disorder 13.38 9.78 128 244410 50688 63193796
Oral pain 13.35 9.78 60 244478 28334 63216150
Bronchial anastomosis complication 13.34 9.78 5 244533 29 63244455
Lung abscess 13.33 9.78 25 244513 1843 63242641
Bradycardia 13.32 9.78 373 244165 72854 63171630
Disability 13.32 9.78 32 244506 18315 63226169
Glomerulonephritis chronic 13.31 9.78 8 244530 148 63244336
Mycoplasma test positive 13.31 9.78 6 244532 59 63244425
Radiculopathy 13.28 9.78 67 244471 8544 63235940
Haematemesis 13.28 9.78 66 244472 30346 63214138
Hyperthermia 13.26 9.78 70 244468 9086 63235398
Abnormal loss of weight 13.26 9.78 3 244535 5779 63238705
Anaemia 13.25 9.78 962 243576 292468 62952016
Hallucination, auditory 13.23 9.78 18 244520 12806 63231678
Deep vein thrombosis 13.21 9.78 235 244303 83565 63160919
Herpes simplex encephalitis 13.20 9.78 11 244527 348 63244136
Breast cancer stage I 13.19 9.78 5 244533 6884 63237600
Myelitis transverse 13.18 9.78 20 244518 1240 63243244
Nasal septum disorder 13.17 9.78 8 244530 151 63244333
Allergy test positive 13.15 9.78 14 244524 606 63243878
Synovial fluid analysis 13.13 9.78 29 244509 2404 63242080
Jaundice neonatal 13.13 9.78 17 244521 908 63243576
Arteriosclerosis coronary artery 13.10 9.78 8 244530 8365 63236119
Chest pain 13.07 9.78 689 243849 215270 63029214
Conjunctivitis 13.06 9.78 130 244408 20666 63223818
Complement factor C4 decreased 13.04 9.78 10 244528 280 63244204
Refractory anaemia with an excess of blasts 13.02 9.78 12 244526 435 63244049
Paraesthesia mucosal 13.01 9.78 4 244534 11 63244473
Cytomegalovirus duodenitis 13.01 9.78 4 244534 11 63244473
Injection site discolouration 12.99 9.78 7 244531 7841 63236643
Vesicoureteric reflux 12.97 9.78 9 244529 215 63244269
Breast abscess 12.97 9.78 24 244514 1752 63242732
Lower respiratory tract congestion 12.95 9.78 32 244506 2854 63241630
Ureteric stenosis 12.95 9.78 14 244524 617 63243867
Stenotrophomonas sepsis 12.93 9.78 5 244533 32 63244452
Metastases to central nervous system 12.91 9.78 19 244519 13086 63231398
Renal impairment 12.86 9.78 438 244100 87917 63156567
Eosinophilic granulomatosis with polyangiitis 12.83 9.78 27 244511 2165 63242319
Graft loss 12.83 9.78 11 244527 362 63244122
Glomerular filtration rate abnormal 12.83 9.78 16 244522 823 63243661
Microsporidia infection 12.83 9.78 10 244528 287 63244197
Muscle strain 12.81 9.78 8 244530 8266 63236218
Oropharyngeal discomfort 12.81 9.78 47 244491 5213 63239271
Germ cell cancer 12.80 9.78 6 244532 65 63244419
CD8 lymphocytes decreased 12.77 9.78 8 244530 160 63244324
Gamma-glutamyltransferase increased 12.76 9.78 193 244345 33838 63210646
Red cell distribution width decreased 12.75 9.78 26 244512 2039 63242445
Irritability 12.60 9.78 71 244467 31623 63212861
Central venous pressure increased 12.60 9.78 7 244531 111 63244373
Laryngeal mass 12.55 9.78 5 244533 35 63244449
Vasculitis necrotising 12.55 9.78 13 244525 545 63243939
Epidural lipomatosis 12.54 9.78 7 244531 112 63244372
Dengue fever 12.52 9.78 14 244524 641 63243843
Respiratory arrest 12.51 9.78 74 244464 32571 63211913
Allergy to plants 12.50 9.78 15 244523 741 63243743
Somnambulism 12.46 9.78 3 244535 5540 63238944
Mucocutaneous leishmaniasis 12.45 9.78 11 244527 377 63244107
Product contamination 12.44 9.78 15 244523 745 63243739
Nerve injury 12.38 9.78 12 244526 9934 63234550
Hypocapnia 12.38 9.78 11 244527 380 63244104
B-lymphocyte count increased 12.38 9.78 7 244531 115 63244369
Musculoskeletal pain 12.35 9.78 266 244272 92011 63152473
Histoplasmosis disseminated 12.34 9.78 21 244517 1435 63243049
Incorrect route of product administration 12.32 9.78 59 244479 27393 63217091
Propofol infusion syndrome 12.32 9.78 17 244521 966 63243518
Proctitis haemorrhagic 12.29 9.78 4 244534 14 63244470
Influenza 12.26 9.78 524 244014 108198 63136286
Pneumocephalus 12.26 9.78 8 244530 172 63244312
Polymenorrhoea 12.23 9.78 19 244519 1202 63243282
Respiratory gas exchange disorder 12.21 9.78 11 244527 387 63244097
Creatinine renal clearance decreased 12.19 9.78 28 244510 16280 63228204
Hyperoxaluria 12.14 9.78 8 244530 175 63244309
Lip swelling 12.13 9.78 70 244468 30993 63213491
Monocyte percentage decreased 12.11 9.78 9 244529 240 63244244
Hypocalcaemia 12.10 9.78 72 244466 31641 63212843
Low birth weight baby 12.09 9.78 57 244481 7072 63237412
Pneumonia acinetobacter 12.09 9.78 5 244533 39 63244445
Ureteric obstruction 12.09 9.78 24 244514 1846 63242638
Haemostasis 12.08 9.78 9 244529 241 63244243
Hyperkalaemia 12.05 9.78 142 244396 54061 63190423
Complications of transplanted liver 12.05 9.78 11 244527 394 63244090
Candida test positive 11.99 9.78 16 244522 880 63243604
Kidney fibrosis 11.99 9.78 24 244514 1857 63242627
Heliotrope rash 11.98 9.78 8 244530 179 63244305
Blood calcium increased 11.97 9.78 11 244527 9339 63235145
Genital herpes 11.95 9.78 23 244515 1729 63242755
Relapsing-remitting multiple sclerosis 11.95 9.78 13 244525 577 63243907
Blood glucose decreased 11.94 9.78 41 244497 20911 63223573
Cardiac failure 11.92 9.78 257 244281 88885 63155599
Muscle hypertrophy 11.91 9.78 6 244532 77 63244407
Hepatitis B 11.88 9.78 37 244501 3775 63240709
Adjusted calcium decreased 11.87 9.78 8 244530 182 63244302
Meningitis cryptococcal 11.85 9.78 20 244518 1357 63243127
Microscopic polyangiitis 11.83 9.78 8 244530 183 63244301
Cytomegalovirus gastritis 11.83 9.78 8 244530 183 63244301
Palmar erythema 11.81 9.78 23 244515 1744 63242740
Foetal growth restriction 11.81 9.78 59 244479 7494 63236990
Enteritis 11.76 9.78 63 244475 8223 63236261
Herpes simplex hepatitis 11.75 9.78 11 244527 407 63244077
Renal artery stenosis 11.75 9.78 24 244514 1885 63242599
Meningitis staphylococcal 11.69 9.78 4 244534 17 63244467
Penicillium infection 11.67 9.78 7 244531 129 63244355
Serum ferritin increased 11.66 9.78 51 244487 6131 63238353
Enterocolitis bacterial 11.64 9.78 9 244529 255 63244229
Feeling cold 11.63 9.78 142 244396 23746 63220738
Blood catecholamines abnormal 11.62 9.78 3 244535 3 63244481
Eosinophil count increased 11.60 9.78 77 244461 10851 63233633
Body height decreased 11.60 9.78 13 244525 10065 63234419
Skin striae 11.60 9.78 20 244518 1381 63243103
Psychiatric decompensation 11.60 9.78 20 244518 1381 63243103
Reticulocytopenia 11.58 9.78 6 244532 82 63244402
Perineal ulceration 11.57 9.78 5 244533 44 63244440
Wound infection bacterial 11.52 9.78 13 244525 601 63243883
Heart transplant rejection 11.50 9.78 13 244525 602 63243882
Intestinal ulcer 11.49 9.78 20 244518 1391 63243093
Enterocolitis viral 11.49 9.78 9 244529 260 63244224
Withdrawal syndrome 11.48 9.78 39 244499 19958 63224526
Capillaritis 11.48 9.78 7 244531 133 63244351
Rhinovirus infection 11.48 9.78 41 244497 4488 63239996
Spinal operation 11.48 9.78 9 244529 8262 63236222
Jaundice cholestatic 11.45 9.78 7 244531 7317 63237167
Parkinsonism 11.44 9.78 14 244524 10425 63234059
Disorientation 11.42 9.78 97 244441 39355 63205129
Transaminases increased 11.42 9.78 177 244361 31190 63213294
Laboratory test abnormal 11.41 9.78 59 244479 26853 63217631
Tuberous sclerosis complex 11.39 9.78 6 244532 85 63244399
Cancer in remission 11.38 9.78 5 244533 46 63244438
Nephrolithiasis 11.37 9.78 105 244433 41879 63202605
Weight increased 11.37 9.78 1159 243379 259633 62984851
Tubulointerstitial nephritis 11.35 9.78 122 244416 19781 63224703
Aspergillus test positive 11.34 9.78 10 244528 342 63244142
Diffuse large B-cell lymphoma stage III 11.29 9.78 5 244533 47 63244437
Intestine transplant rejection 11.29 9.78 5 244533 47 63244437
Tachypnoea 11.28 9.78 109 244429 17193 63227291
Glucose urine present 11.26 9.78 14 244524 718 63243766
Angiocentric lymphoma 11.23 9.78 13 244525 618 63243866
Hyperferritinaemia 11.21 9.78 8 244530 200 63244284
Mouth ulceration 11.21 9.78 184 244354 32800 63211684
Tumour lysis syndrome 11.20 9.78 66 244472 8924 63235560
Osteogenesis imperfecta 11.20 9.78 13 244525 620 63243864
Locked-in syndrome 11.19 9.78 11 244527 433 63244051
Pneumoperitoneum 11.17 9.78 20 244518 1423 63243061
Large intestine polyp 11.17 9.78 9 244529 8148 63236336
Neonatal pneumonia 11.16 9.78 4 244534 20 63244464
Organising pneumonia 11.16 9.78 48 244490 5728 63238756
Hepatic steatosis 11.14 9.78 65 244473 28704 63215780
Moraxella infection 11.12 9.78 11 244527 436 63244048
Enteritis infectious 11.11 9.78 25 244513 2099 63242385
Organic brain syndrome 11.11 9.78 8 244530 203 63244281
Varicose ulceration 11.09 9.78 12 244526 529 63243955
Acute lymphocytic leukaemia recurrent 11.09 9.78 26 244512 2243 63242241
Acute disseminated encephalomyelitis 11.07 9.78 8 244530 204 63244280
Respiratory tract oedema 11.02 9.78 12 244526 533 63243951
Expired product administered 11.01 9.78 5 244533 6176 63238308
Cerebral vasoconstriction 11.01 9.78 18 244520 1190 63243294
Cholecystectomy 11.00 9.78 15 244523 10662 63233822
Therapeutic response shortened 11.00 9.78 81 244457 11807 63232677
Fracture pain 10.93 9.78 14 244524 740 63243744
Adjustment disorder with depressed mood 10.85 9.78 14 244524 10190 63234294
Coagulation factor VIII level increased 10.85 9.78 4 244534 22 63244462
Bulbar palsy 10.85 9.78 4 244534 22 63244462
Joint injury 10.83 9.78 68 244470 29504 63214980
Poor quality sleep 10.82 9.78 121 244417 19814 63224670
Human herpesvirus 6 infection reactivation 10.82 9.78 10 244528 364 63244120
Retinal depigmentation 10.82 9.78 9 244529 284 63244200
Antinuclear antibody positive 10.80 9.78 60 244478 7939 63236545
Angina unstable 10.79 9.78 7 244531 7088 63237396
Bone marrow reticulin fibrosis 10.78 9.78 8 244530 213 63244271
Meningitis listeria 10.77 9.78 13 244525 646 63243838
Diffuse large B-cell lymphoma refractory 10.77 9.78 18 244520 1212 63243272
Creatinine urine increased 10.76 9.78 9 244529 286 63244198
Eye infection toxoplasmal 10.76 9.78 9 244529 286 63244198
Hepatitis acute 10.75 9.78 66 244472 9054 63235430
Ageusia 10.73 9.78 23 244515 13705 63230779
Fungal test positive 10.72 9.78 12 244526 550 63243934
Corynebacterium sepsis 10.70 9.78 4 244534 23 63244461
Complement factor C3 decreased 10.68 9.78 9 244529 289 63244195
Pseudomonal bacteraemia 10.65 9.78 21 244517 1607 63242877
Vein rupture 10.63 9.78 18 244520 1225 63243259
Eosinophil percentage decreased 10.62 9.78 8 244530 218 63244266
Herpes simplex reactivation 10.61 9.78 12 244526 556 63243928
Tendon rupture 10.60 9.78 61 244477 8178 63236306
Viral myocarditis 10.58 9.78 9 244529 293 63244191
Oral fungal infection 10.57 9.78 31 244507 3060 63241424
Tuberculosis of genitourinary system 10.56 9.78 4 244534 24 63244460
Otitis externa 10.55 9.78 22 244516 1753 63242731
Lower respiratory tract infection bacterial 10.54 9.78 11 244527 465 63244019
Adenoviral haemorrhagic cystitis 10.51 9.78 7 244531 156 63244328
Aplastic anaemia 10.51 9.78 68 244470 9501 63234983
Human papilloma virus test positive 10.49 9.78 12 244526 563 63243921
Enterovirus infection 10.47 9.78 16 244522 998 63243486
Bradyphrenia 10.47 9.78 7 244531 6973 63237511
Foetal exposure during pregnancy 10.46 9.78 76 244462 31886 63212598
Haemangioma-thrombocytopenia syndrome 10.42 9.78 3 244535 6 63244478
Osseous cryptococcosis 10.42 9.78 3 244535 6 63244478
Eye inflammation 10.41 9.78 46 244492 5553 63238931
Treatment failure 10.41 9.78 644 243894 198399 63046085
Large intestine perforation 10.39 9.78 62 244476 8420 63236064
Chromosomal deletion 10.38 9.78 6 244532 103 63244381
Blood potassium increased 10.32 9.78 36 244502 18273 63226211
Acute motor axonal neuropathy 10.29 9.78 4 244534 26 63244458
Pneumonia pseudomonal 10.24 9.78 27 244511 2506 63241978
Thrombocytosis 10.22 9.78 47 244491 5771 63238713
Anaplastic astrocytoma 10.22 9.78 5 244533 60 63244424
Procalcitonin increased 10.20 9.78 17 244521 1142 63243342
Incorrect product administration duration 10.19 9.78 18 244520 11528 63232956
Lung disorder 10.19 9.78 313 244225 61948 63182536
Monocytopenia 10.15 9.78 5 244533 61 63244423
Vascular device infection 10.10 9.78 8 244530 7304 63237180
Somnolence 10.08 9.78 574 243964 178111 63066373
Intestinal infarction 10.05 9.78 16 244522 1034 63243450
Injection site haematoma 10.05 9.78 7 244531 6825 63237659
Occult blood 10.03 9.78 18 244520 1283 63243201
Therapeutic product effect incomplete 10 9.78 387 244151 124669 63119815
Atrioventricular block first degree 9.99 9.78 8 244530 7265 63237219
Human herpesvirus 6 encephalitis 9.99 9.78 8 244530 239 63244245
Hand dermatitis 9.93 9.78 8 244530 241 63244243
Lymphocyte count abnormal 9.93 9.78 13 244525 702 63243782
Myalgia 9.93 9.78 462 244076 146067 63098417
Enterobacter pneumonia 9.92 9.78 4 244534 29 63244455
Hyperuricaemia 9.90 9.78 44 244494 5326 63239158
Rosacea 9.89 9.78 40 244498 4644 63239840
Human polyomavirus infection 9.89 9.78 9 244529 321 63244163
Back disorder 9.89 9.78 17 244521 11000 63233484
Oxygen saturation abnormal 9.86 9.78 33 244505 3496 63240988
Groin pain 9.85 9.78 15 244523 10188 63234296
Calcium ionised increased 9.84 9.78 6 244532 114 63244370
Drug level below therapeutic 9.84 9.78 41 244497 4825 63239659
Listeria test positive 9.82 9.78 3 244535 8 63244476
Low cardiac output syndrome 9.81 9.78 10 244528 411 63244073
Thirst 9.79 9.78 25 244513 14016 63230468
Drug monitoring procedure not performed 9.79 9.78 12 244526 606 63243878
Atrioventricular block 9.78 9.78 9 244529 7638 63236846

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Off label use 1167.31 10.72 4244 148747 415280 34388660
Cytomegalovirus infection 879.79 10.72 804 152187 25331 34778609
Drug ineffective for unapproved indication 522.51 10.72 580 152411 23135 34780805
Product use in unapproved indication 477.30 10.72 1358 151633 116141 34687799
Death 420.44 10.72 686 152305 397363 34406577
Infusion related reaction 408.05 10.72 788 152203 52269 34751671
Drug ineffective 385.24 10.72 3351 149640 453400 34350540
Transplant rejection 350.25 10.72 319 152672 9992 34793948
Drug abuse 346.67 10.72 22 152969 99074 34704866
Completed suicide 345.80 10.72 21 152970 98147 34705793
Pneumocystis jirovecii pneumonia 323.54 10.72 415 152576 19295 34784645
Bronchopulmonary aspergillosis 318.48 10.72 356 152635 14303 34789637
Aspergillus infection 318.04 10.72 327 152664 11927 34792013
Post transplant lymphoproliferative disorder 305.91 10.72 243 152748 6285 34797655
Kidney transplant rejection 296.75 10.72 253 152738 7244 34796696
Graft versus host disease 296.18 10.72 294 152697 10275 34793665
Multiple organ dysfunction syndrome 294.17 10.72 868 152123 75698 34728242
Mucormycosis 282.33 10.72 223 152768 5719 34798221
Cytomegalovirus viraemia 274.39 10.72 241 152750 7189 34796751
Strongyloidiasis 273.41 10.72 162 152829 2549 34801391
Epstein-Barr virus infection 268.91 10.72 241 152750 7387 34796553
Product dose omission issue 253.96 10.72 103 152888 119608 34684332
Toxicity to various agents 247.70 10.72 308 152683 200054 34603886
Thrombotic microangiopathy 242.72 10.72 265 152726 10365 34793575
Fall 235.32 10.72 327 152664 202558 34601382
Respiratory failure 235.31 10.72 1020 151971 107552 34696388
Posterior reversible encephalopathy syndrome 225.28 10.72 247 152744 9707 34794233
Blood pressure diastolic abnormal 218.61 10.72 176 152815 4642 34799298
Acute graft versus host disease in skin 215.06 10.72 180 152811 5021 34798919
Septic shock 211.02 10.72 743 152248 71091 34732849
Fatigue 200.89 10.72 888 152103 369765 34434175
Pneumatosis intestinalis 196.70 10.72 152 152839 3771 34800169
Complications of transplanted kidney 193.66 10.72 161 152830 4448 34799492
Adenovirus infection 193.07 10.72 170 152821 5087 34798853
Blood pressure fluctuation 189.06 10.72 371 152620 24878 34779062
Dizziness 179.57 10.72 435 152556 218086 34585854
Graft versus host disease in gastrointestinal tract 174.49 10.72 138 152853 3545 34800395
Cytomegalovirus test positive 174.29 10.72 141 152850 3745 34800195
Oxygen saturation decreased 163.49 10.72 563 152428 53255 34750685
Nausea 162.66 10.72 851 152140 339057 34464883
Nocardiosis 161.83 10.72 136 152855 3815 34800125
Blood pressure systolic abnormal 159.86 10.72 135 152856 3813 34800127
BK virus infection 159.61 10.72 159 152832 5579 34798361
Syncope 159.09 10.72 102 152889 91349 34712591
Polyomavirus-associated nephropathy 158.86 10.72 133 152858 3711 34800229
Acute graft versus host disease 155.26 10.72 166 152825 6337 34797603
Cytomegalovirus infection reactivation 153.90 10.72 148 152843 4970 34798970
Myocardial infarction 150.63 10.72 185 152806 120900 34683040
Disseminated intravascular coagulation 147.18 10.72 307 152684 21509 34782431
Haemophagocytic lymphohistiocytosis 145.84 10.72 228 152763 12745 34791195
Candida infection 144.54 10.72 270 152721 17445 34786495
Blood pressure systolic increased 143.33 10.72 313 152678 22639 34781301
Cardiac failure congestive 143.30 10.72 94 152897 83176 34720764
Graft versus host disease in skin 142.29 10.72 126 152865 3799 34800141
Cystitis haemorrhagic 140.96 10.72 148 152843 5531 34798409
Acute graft versus host disease in liver 138.42 10.72 86 152905 1480 34802460
Acute graft versus host disease in intestine 135.94 10.72 105 152886 2603 34801337
Intentional overdose 135.56 10.72 16 152975 43658 34760282
Pneumonia cytomegaloviral 135.25 10.72 110 152881 2944 34800996
Steroid diabetes 134.61 10.72 96 152895 2099 34801841
Hospitalisation 127.18 10.72 45 152946 56857 34747083
Asthenia 121.64 10.72 606 152385 244645 34559295
Enterococcal infection 118.01 10.72 173 152818 9133 34794807
Dehydration 116.96 10.72 246 152745 129723 34674217
Overdose 116.54 10.72 136 152855 90923 34713017
Pseudomonas infection 115.42 10.72 200 152791 12182 34791758
Human herpesvirus 6 infection 113.98 10.72 85 152906 1996 34801944
Cerebrovascular accident 107.10 10.72 128 152863 84683 34719257
Parvovirus B19 infection 104.72 10.72 58 152933 797 34803143
Pneumomediastinum 104.28 10.72 85 152906 2282 34801658
Acute respiratory distress syndrome 103.98 10.72 299 152692 25670 34778270
Coronary artery disease 103.26 10.72 41 152950 48264 34755676
Disseminated mucormycosis 101.93 10.72 49 152942 491 34803449
Constipation 101.42 10.72 287 152704 136695 34667245
Chronic graft versus host disease 98.05 10.72 108 152883 4265 34799675
Blood pressure increased 96.26 10.72 688 152303 87414 34716526
Vomiting 95.52 10.72 663 152328 246958 34556982
Heart rate decreased 95.40 10.72 331 152660 31414 34772526
Lymphocyte count decreased 94.02 10.72 264 152727 22358 34781582
Rebound effect 93.42 10.72 92 152899 3182 34800758
Klebsiella infection 89.11 10.72 145 152846 8386 34795554
Infection reactivation 88.39 10.72 64 152927 1434 34802506
Hypoglycaemia 86.99 10.72 67 152924 54573 34749367
Wrong technique in product usage process 84.72 10.72 26 152965 35960 34767980
Immunosuppressant drug level increased 83.28 10.72 117 152874 5938 34798002
Suicide attempt 82.30 10.72 34 152957 39082 34764858
Bacterial sepsis 80.60 10.72 107 152884 5143 34798797
Depression 79.80 10.72 193 152798 96905 34707035
Pyrexia 78.65 10.72 1959 151032 331054 34472886
Intentional product use issue 77.87 10.72 488 152503 59328 34744612
Cushingoid 76.95 10.72 76 152915 2638 34801302
Delayed graft function 75.96 10.72 69 152922 2152 34801788
Intentional product misuse 75.09 10.72 54 152937 45557 34758383
Cryptococcosis 74.72 10.72 71 152920 2348 34801592
Injection site pain 74.19 10.72 39 152952 38966 34764974
Feeling abnormal 73.04 10.72 102 152889 63133 34740807
Central nervous system fungal infection 72.93 10.72 34 152957 316 34803624
Diarrhoea 72.86 10.72 1235 151756 388677 34415263
Drug interaction 72.57 10.72 636 152355 225310 34578630
Therapy non-responder 71.46 10.72 350 152641 38796 34765144
Lymphopenia 71.21 10.72 194 152797 16141 34787799
Systemic mycosis 70.38 10.72 57 152934 1516 34802424
Drug resistance 69.95 10.72 261 152730 25666 34778274
Cytomegalovirus colitis 69.89 10.72 73 152918 2711 34801229
Focal segmental glomerulosclerosis 69.43 10.72 63 152928 1962 34801978
Progressive multifocal leukoencephalopathy 68.90 10.72 140 152851 9624 34794316
Decreased appetite 68.85 10.72 436 152555 165956 34637984
Hyperglycaemia 68.54 10.72 348 152643 39132 34764808
Pulmonary nocardiosis 68.19 10.72 45 152946 863 34803077
Cytomegalovirus enteritis 66.54 10.72 36 152955 471 34803469
Mycobacterium chelonae infection 65.14 10.72 42 152949 773 34803167
Condition aggravated 64.75 10.72 1191 151800 191005 34612935
Pulmonary mucormycosis 64.19 10.72 41 152950 742 34803198
Liver transplant rejection 63.19 10.72 61 152930 2058 34801882
Nephropathy toxic 62.54 10.72 157 152834 12431 34791509
Fungal infection 62.36 10.72 182 152809 15753 34788187
International normalised ratio increased 62.34 10.72 69 152922 47258 34756682
Confusional state 62.09 10.72 373 152618 143787 34660153
Epstein-Barr virus associated lymphoproliferative disorder 61.34 10.72 58 152933 1906 34802034
Cytomegalovirus oesophagitis 61.08 10.72 34 152957 472 34803468
Orthostatic hypotension 60.52 10.72 19 152972 25900 34778040
Rhinocerebral mucormycosis 60.06 10.72 35 152956 533 34803407
Prostate cancer 58.91 10.72 52 152939 39597 34764343
Transplant dysfunction 58.66 10.72 65 152926 2584 34801356
Pneumocystis jirovecii infection 58.61 10.72 54 152937 1716 34802224
Anaphylactic shock 58.53 10.72 178 152813 15763 34788177
Myalgia 58.03 10.72 182 152809 83928 34720012
Cardiac disorder 57.77 10.72 62 152929 43064 34760876
Suicidal ideation 57.60 10.72 55 152936 40333 34763607
COVID-19 57.49 10.72 555 152436 76995 34726945
Herpes simplex 56.05 10.72 93 152898 5466 34798474
Gastroenteritis norovirus 55.34 10.72 49 152942 1477 34802463
Renal tubular necrosis 54.70 10.72 172 152819 15508 34788432
Pulmonary alveolar haemorrhage 54.54 10.72 109 152882 7403 34796537
Drug effective for unapproved indication 54.46 10.72 62 152929 2540 34801400
Enterobacter infection 54.45 10.72 60 152931 2370 34801570
Dyspnoea 53.81 10.72 1248 151743 375534 34428406
Renal transplant failure 53.59 10.72 42 152949 1064 34802876
Mycobacterium abscessus infection 53.53 10.72 32 152959 512 34803428
Serotonin syndrome 53.48 10.72 11 152980 19922 34784018
Staphylococcal sepsis 53.40 10.72 127 152864 9717 34794223
Cytomegalovirus chorioretinitis 53.34 10.72 72 152919 3517 34800423
Blood pressure diastolic increased 53.28 10.72 86 152905 4939 34799001
Oliguria 53.12 10.72 115 152876 8265 34795675
Chronic allograft nephropathy 52.99 10.72 44 152947 1213 34802727
Muscle spasms 52.65 10.72 161 152830 74840 34729100
Pemphigus 52.54 10.72 49 152942 1582 34802358
Rhabdomyolysis 51.73 10.72 141 152850 68022 34735918
Leukopenia 51.70 10.72 460 152531 62396 34741544
Renal tubular atrophy 51.45 10.72 42 152949 1130 34802810
Product prescribing error 51.44 10.72 18 152973 22909 34781031
Peripheral swelling 51.14 10.72 168 152823 76373 34727567
Transplant failure 50.87 10.72 70 152921 3483 34800457
Lymphocyte percentage decreased 50.14 10.72 54 152937 2078 34801862
Plasma cell myeloma 49.34 10.72 67 152924 41970 34761970
Disseminated strongyloidiasis 48.98 10.72 22 152969 186 34803754
Oedema peripheral 48.98 10.72 315 152676 119497 34684443
Disease recurrence 48.82 10.72 205 152786 21285 34782655
Cytomegalovirus enterocolitis 48.71 10.72 38 152953 956 34802984
Amoebic colitis 48.65 10.72 18 152973 86 34803854
Chorioretinopathy 48.37 10.72 45 152946 1448 34802492
Acinetobacter infection 48.30 10.72 41 152950 1166 34802774
Red blood cells urine positive 48.24 10.72 49 152942 1760 34802180
Disseminated cryptococcosis 47.29 10.72 43 152948 1343 34802597
Cytokine release syndrome 47.20 10.72 212 152779 22665 34781275
Viral haemorrhagic cystitis 47.05 10.72 40 152951 1140 34802800
Skin striae 46.91 10.72 31 152960 596 34803344
COVID-19 pneumonia 46.76 10.72 172 152819 16795 34787145
Psoriasis 46.43 10.72 61 152930 38751 34765189
Transient ischaemic attack 46.35 10.72 32 152959 27581 34776359
Graft versus host disease in liver 46.10 10.72 41 152950 1243 34802697
Pneumonia acinetobacter 46 10.72 18 152973 103 34803837
Pneumoretroperitoneum 45.97 10.72 19 152972 128 34803812
Neutrophil percentage increased 45.90 10.72 48 152943 1785 34802155
Epstein-Barr viraemia 45.34 10.72 41 152950 1271 34802669
Pneumonia cryptococcal 45.26 10.72 35 152956 869 34803071
Erectile dysfunction 44.94 10.72 17 152974 20620 34783320
Human ehrlichiosis 44.92 10.72 25 152966 347 34803593
Lethargy 44.86 10.72 69 152922 41053 34762887
Accidental overdose 44.86 10.72 16 152975 20124 34783816
Corynebacterium infection 44.59 10.72 30 152961 595 34803345
Myopathy 44.29 10.72 131 152860 11423 34792517
Loss of personal independence in daily activities 44.11 10.72 48 152943 33131 34770809
Aggression 43.84 10.72 64 152927 38900 34765040
Back pain 43.50 10.72 333 152658 121456 34682484
Intensive care unit acquired weakness 43.40 10.72 36 152955 991 34802949
Adenoviral hepatitis 43.40 10.72 28 152963 516 34803424
Escherichia infection 43.25 10.72 105 152886 8140 34795800
Intentional self-injury 42.83 10.72 5 152986 13766 34790174
Pneumonia pseudomonal 42.79 10.72 68 152923 3854 34800086
Full blood count decreased 42.69 10.72 13 152978 18075 34785865
Balance disorder 42.66 10.72 70 152921 40584 34763356
Somnolence 42.48 10.72 298 152693 110818 34693122
Abdominal discomfort 42.31 10.72 128 152863 59707 34744233
Diffuse large B-cell lymphoma 42.07 10.72 97 152894 7273 34796667
Hypoalbuminaemia 41.97 10.72 133 152858 12041 34791899
Staphylococcal infection 41.82 10.72 266 152725 32494 34771446
Accidental exposure to product 41.48 10.72 4 152987 12798 34791142
Varicella zoster virus infection 41.18 10.72 45 152946 1761 34802179
Necrotising retinitis 40.85 10.72 32 152959 810 34803130
Cutaneous mucormycosis 40.72 10.72 19 152972 177 34803763
Granulomatosis with polyangiitis 40.36 10.72 37 152954 1168 34802772
Osteonecrosis 40.24 10.72 150 152841 14740 34789200
Phaeohyphomycosis 40.13 10.72 32 152959 832 34803108
Sepsis 40.08 10.72 983 152008 165578 34638362
Dural arteriovenous fistula 40.06 10.72 13 152978 38 34803902
Diffuse alveolar damage 39.97 10.72 50 152941 2264 34801676
Kidney fibrosis 39.86 10.72 49 152942 2179 34801761
Systemic candida 39.82 10.72 64 152927 3662 34800278
Dry skin 39.70 10.72 47 152944 31240 34772700
Treatment noncompliance 39.21 10.72 39 152952 28061 34775879
Urine analysis abnormal 39.06 10.72 46 152945 1955 34801985
Pneumonia fungal 38.95 10.72 92 152899 7008 34796932
Fungaemia 38.90 10.72 52 152939 2516 34801424
Psoriatic arthropathy 38.83 10.72 19 152972 19779 34784161
Dyspnoea exertional 38.80 10.72 82 152909 43197 34760743
Malaise 38.42 10.72 577 152414 185248 34618692
Gait disturbance 38.38 10.72 217 152774 84923 34719017
Chest pain 38.36 10.72 362 152629 126400 34677540
Malignant neoplasm progression 38.30 10.72 227 152764 87819 34716121
Osmotic demyelination syndrome 38.29 10.72 31 152960 824 34803116
Penicillium infection 37.72 10.72 16 152975 116 34803824
Urine abnormality 37.45 10.72 45 152946 1954 34801986
Serum sickness 37.43 10.72 45 152946 1955 34801985
Apoptosis 37.41 10.72 23 152968 388 34803552
Adverse event 37.20 10.72 18 152973 18859 34785081
Product quality issue 37.15 10.72 14 152977 17021 34786919
Pain in extremity 37.13 10.72 364 152627 126149 34677791
Sedation 37.08 10.72 23 152968 20983 34782957
Extrapyramidal disorder 36.94 10.72 6 152985 12874 34791066
Intra-abdominal haemorrhage 36.91 10.72 49 152942 2355 34801585
Human herpesvirus 8 infection 36.74 10.72 32 152959 943 34802997
Pain 36.55 10.72 653 152338 204022 34599918
Intestinal ischaemia 36.43 10.72 95 152896 7699 34796241
Necrosis ischaemic 36.29 10.72 20 152971 272 34803668
Insomnia 35.75 10.72 287 152704 103620 34700320
Viraemia 35.72 10.72 35 152956 1203 34802737
Dry mouth 35.48 10.72 48 152943 30117 34773823
Hypertension 35.48 10.72 814 152177 135629 34668311
Incision site pain 35.46 10.72 42 152949 1796 34802144
JC virus infection 35.44 10.72 46 152945 2162 34801778
Pneumothorax 35.04 10.72 171 152820 18921 34785019
Anxiety 34.96 10.72 273 152718 99155 34704785
Haemodynamic instability 34.64 10.72 106 152885 9417 34794523
Atrial fibrillation 34.32 10.72 356 152635 122037 34681903
Aplastic anaemia 34.28 10.72 107 152884 9609 34794331
Contusion 34.21 10.72 67 152924 36297 34767643
Large intestine perforation 34.12 10.72 98 152893 8405 34795535
Quadriplegia 34.02 10.72 41 152950 1786 34802154
Injection site swelling 33.90 10.72 5 152986 11522 34792418
Crystal urine present 33.50 10.72 23 152968 472 34803468
Immunosuppressant drug level decreased 33.50 10.72 34 152957 1220 34802720
Ureteric stenosis 33.47 10.72 33 152958 1143 34802797
Central nervous system infection 33.33 10.72 26 152965 654 34803286
Pneumonia bacterial 33.26 10.72 121 152870 11751 34792189
American trypanosomiasis 33.04 10.72 18 152973 239 34803701
Diabetes mellitus 33.03 10.72 332 152659 46541 34757399
Skin necrosis 32.28 10.72 76 152915 5777 34798163
Full blood count abnormal 32.18 10.72 21 152970 18647 34785293
Perinephric abscess 31.68 10.72 11 152980 42 34803898
Hypophagia 31.65 10.72 35 152956 23987 34779953
Depressed mood 31.61 10.72 23 152968 19294 34784646
Bacteraemia 31.59 10.72 170 152821 19547 34784393
Neuropathy peripheral 31.47 10.72 224 152767 83039 34720901
Glomerulonephritis 31.42 10.72 41 152950 1937 34802003
Mycotic endophthalmitis 31.40 10.72 13 152978 88 34803852
Febrile bone marrow aplasia 31.39 10.72 93 152898 8116 34795824
Adverse drug reaction 31.27 10.72 50 152941 29292 34774648
Headache 31.26 10.72 655 152336 199980 34603960
Venoocclusive liver disease 31.18 10.72 91 152900 7875 34796065
Neuroleptic malignant syndrome 31.16 10.72 20 152971 17914 34786026
Memory impairment 31.10 10.72 92 152899 43226 34760714
Blood pressure diastolic decreased 31.03 10.72 99 152892 8995 34794945
General physical health deterioration 30.90 10.72 386 152605 127883 34676057
Cerebral fungal infection 30.89 10.72 18 152973 274 34803666
Polychondritis 30.73 10.72 17 152974 233 34803707
Glomerulosclerosis 30.71 10.72 27 152964 806 34803134
Product substitution issue 30.58 10.72 4 152987 10091 34793849
Osteomyelitis fungal 30.54 10.72 17 152974 236 34803704
Porphyria acute 30.53 10.72 19 152972 328 34803612
Hallucination 30.42 10.72 119 152872 51379 34752561
Fusarium infection 30.17 10.72 31 152960 1129 34802811
Pyelonephritis acute 30.13 10.72 41 152950 2018 34801922
Cytomegalovirus hepatitis 30.13 10.72 21 152970 442 34803498
Hypogammaglobulinaemia 29.90 10.72 88 152903 7652 34796288
Renal impairment 29.79 10.72 580 152411 93933 34710007
Respiratory arrest 29.69 10.72 48 152943 27995 34775945
Hyperkalaemia 29.59 10.72 180 152811 69209 34734731
Thrombosis 29.55 10.72 117 152874 50341 34753599
Haemolytic anaemia 29.52 10.72 107 152884 10372 34793568
Nightmare 29.48 10.72 13 152978 14378 34789562
Dysgeusia 29.34 10.72 44 152947 26453 34777487
Disseminated varicella zoster virus infection 29.31 10.72 18 152973 303 34803637
Pharyngeal paraesthesia 28.92 10.72 24 152967 661 34803279
Herpes zoster 28.92 10.72 253 152738 34146 34769794
Throat irritation 28.91 10.72 107 152884 10478 34793462
Blood creatine phosphokinase increased 28.89 10.72 100 152891 44757 34759183
Anaemia 28.84 10.72 789 152202 232546 34571394
Renal tubular injury 28.75 10.72 28 152963 955 34802985
Injection site erythema 28.63 10.72 17 152974 15882 34788058
Bronchopleural fistula 28.57 10.72 21 152970 482 34803458
Symptom masked 28.32 10.72 23 152968 614 34803326
Haemolytic uraemic syndrome 28.26 10.72 42 152949 2244 34801696
Parvovirus infection 28.21 10.72 20 152971 433 34803507
Protein urine present 27.87 10.72 67 152924 5161 34798779
Candida sepsis 27.66 10.72 31 152960 1248 34802692
Laboratory test abnormal 27.66 10.72 29 152962 20362 34783578
Subcutaneous emphysema 27.66 10.72 30 152961 1164 34802776
Opportunistic infection 27.33 10.72 35 152956 1623 34802317
Drug intolerance 27.29 10.72 151 152840 59419 34744521
Neck pain 27.20 10.72 43 152948 25306 34778634
Drug withdrawal syndrome 27.14 10.72 28 152963 19806 34784134
Gastrointestinal candidiasis 26.93 10.72 14 152977 168 34803772
Blood beta-D-glucan increased 26.85 10.72 19 152972 410 34803530
Poisoning 26.74 10.72 10 152981 12216 34791724
Toxic epidermal necrolysis 26.54 10.72 174 152817 21472 34782468
Obliterative bronchiolitis 26.47 10.72 30 152961 1223 34802717
Pseudomonal sepsis 26.39 10.72 52 152939 3495 34800445
Acute myocardial infarction 26.37 10.72 133 152858 53586 34750354
Palmar-plantar erythrodysaesthesia syndrome 26.20 10.72 21 152970 16774 34787166
Antineutrophil cytoplasmic antibody positive 26.12 10.72 24 152967 760 34803180
Proteinuria 26.08 10.72 155 152836 18487 34785453
Polyomavirus viraemia 25.94 10.72 26 152965 919 34803021
Lung abscess 25.85 10.72 44 152947 2641 34801299
Angiosarcoma 25.82 10.72 16 152975 274 34803666
Unevaluable event 25.79 10.72 66 152925 32524 34771416
Respiratory tract infection fungal 25.68 10.72 23 152968 704 34803236
Red blood cell schistocytes present 25.65 10.72 15 152976 230 34803710
Cytomegalovirus gastritis 25.42 10.72 15 152976 234 34803706
Monocyte percentage increased 25.39 10.72 26 152965 943 34802997
Respiratory distress 25.31 10.72 253 152738 35412 34768528
Pneumonia klebsiella 25.31 10.72 49 152942 3251 34800689
Oesophageal carcinoma 25.24 10.72 5 152986 9299 34794641
Human polyomavirus infection 25.22 10.72 23 152968 721 34803219
Sleep disorder 25.21 10.72 64 152927 31624 34772316
C-reactive protein abnormal 25.11 10.72 4 152987 8706 34795234
Hyponatraemia 25.05 10.72 236 152755 82455 34721485
Tremor 24.90 10.72 236 152755 82351 34721589
Coronary artery dilatation 24.75 10.72 8 152983 23 34803917
Systemic inflammatory response syndrome 24.70 10.72 75 152916 6634 34797306
Immunosuppression 24.66 10.72 72 152919 6232 34797708
Cryptococcal meningoencephalitis 24.39 10.72 12 152979 127 34803813
Osteoporosis 24.36 10.72 115 152876 12553 34791387
Anaphylactic reaction 24.32 10.72 232 152759 32069 34771871
Epstein-Barr virus infection reactivation 24.29 10.72 27 152964 1077 34802863
Red cell distribution width increased 24.02 10.72 70 152921 6053 34797887
Pulmonary haemorrhage 23.95 10.72 99 152892 10205 34793735
Electrocardiogram QT prolonged 23.95 10.72 95 152896 40857 34763083
Complications of transplant surgery 23.92 10.72 19 152972 491 34803449
Reticulocytosis 23.80 10.72 15 152976 265 34803675
Pneumoperitoneum 23.74 10.72 34 152957 1756 34802184
Stress 23.60 10.72 62 152929 30285 34773655
Cholelithiasis 23.53 10.72 35 152956 21113 34782827
Staphylococcal mediastinitis 23.52 10.72 9 152982 48 34803892
Encephalitis fungal 23.51 10.72 13 152978 178 34803762
Specific gravity urine increased 23.45 10.72 12 152979 139 34803801
Viral sepsis 23.34 10.72 11 152980 105 34803835
Renal graft infection 23.27 10.72 15 152976 276 34803664
Device issue 23.12 10.72 7 152984 9770 34794170
Hepatic failure 23.09 10.72 242 152749 34289 34769651
Injection site haemorrhage 23.09 10.72 7 152984 9761 34794179
Engraftment syndrome 23.01 10.72 25 152966 972 34802968
Pseudomonal bacteraemia 22.97 10.72 30 152961 1419 34802521
Abnormal dreams 22.96 10.72 3 152988 7575 34796365
Viral cardiomyopathy 22.95 10.72 8 152983 31 34803909
Leukocytosis 22.89 10.72 182 152809 23883 34780057
Adenoviral haemorrhagic cystitis 22.87 10.72 17 152974 397 34803543
Gastric disorder 22.83 10.72 13 152978 12428 34791512
Akathisia 22.76 10.72 4 152987 8105 34795835
Bifidobacterium infection 22.75 10.72 8 152983 32 34803908
Disturbance in attention 22.55 10.72 50 152941 25895 34778045
Alveolar proteinosis 22.54 10.72 18 152973 469 34803471
Subdural haematoma 22.52 10.72 34 152957 20387 34783553
Unresponsive to stimuli 22.46 10.72 55 152936 27514 34776426
Lymphoproliferative disorder 22.43 10.72 42 152949 2717 34801223
Disseminated blastomycosis 22.38 10.72 12 152979 154 34803786
Sideroblastic anaemia 22.33 10.72 14 152977 245 34803695
Pneumocephalus 22.31 10.72 12 152979 155 34803785
B-cell lymphoma 22.28 10.72 55 152936 4308 34799632
Dyskinesia 22.22 10.72 40 152951 22373 34781567
Peritonitis 22.21 10.72 135 152856 16230 34787710
Lupus nephritis 22.15 10.72 16 152975 357 34803583
Respiratory depression 22.15 10.72 23 152968 16222 34787718
Abdominal pain upper 22.10 10.72 203 152788 71287 34732653
B-lymphocyte count decreased 22.04 10.72 20 152971 623 34803317
Cutaneous malacoplakia 22.02 10.72 10 152981 87 34803853
Epstein-Barr virus test positive 21.99 10.72 19 152972 554 34803386
Graft loss 21.89 10.72 23 152968 860 34803080
Graft complication 21.81 10.72 16 152975 366 34803574
Low birth weight baby 21.67 10.72 80 152911 7825 34796115
Amoebiasis 21.61 10.72 9 152982 62 34803878
Neurological decompensation 21.49 10.72 43 152948 2923 34801017
Hypersomnia 21.33 10.72 14 152977 12393 34791547
Respiratory disorder 21.32 10.72 151 152840 19113 34784827
Fungal skin infection 21.30 10.72 40 152951 2594 34801346
Gastroenteritis Escherichia coli 21.26 10.72 16 152975 381 34803559
Terminal ileitis 21.11 10.72 13 152978 220 34803720
Erythema 21.02 10.72 523 152468 88257 34715683
Therapy cessation 21.00 10.72 26 152965 16947 34786993
Scopulariopsis infection 20.91 10.72 10 152981 99 34803841
Injection site bruising 20.86 10.72 6 152985 8657 34795283
Atypical mycobacterial pneumonia 20.80 10.72 11 152980 137 34803803
Salivary hypersecretion 20.79 10.72 6 152985 8638 34795302
Product storage error 20.74 10.72 5 152986 8117 34795823
Thyrotoxic periodic paralysis 20.73 10.72 11 152980 138 34803802
Diarrhoea haemorrhagic 20.72 10.72 71 152920 6693 34797247
Injection site reaction 20.71 10.72 16 152975 13017 34790923
Body temperature decreased 20.62 10.72 112 152879 12922 34791018
Vasculitis 20.60 10.72 101 152890 11195 34792745
Wound evisceration 20.48 10.72 10 152981 104 34803836
Hospice care 20.43 10.72 3 152988 6937 34797003
Splenic embolism 20.35 10.72 12 152979 187 34803753
Heart transplant rejection 20.31 10.72 26 152965 1205 34802735
Chills 20.27 10.72 481 152510 80562 34723378
Mobility decreased 20.20 10.72 66 152925 30062 34773878
Thrombocytopenia 20.15 10.72 856 152135 155391 34648549
Disseminated coccidioidomycosis 20.15 10.72 9 152982 75 34803865
Hepatitis A 20.10 10.72 17 152974 481 34803459
Bladder cancer 20.07 10.72 25 152966 16253 34787687
Incorrect dose administered 20.06 10.72 100 152891 40415 34763525
Medication error 20.05 10.72 52 152939 25513 34778427
Herpes simplex viraemia 20.05 10.72 9 152982 76 34803864
Muscle twitching 20.02 10.72 10 152981 10288 34793652
Enterococcus test positive 19.92 10.72 24 152967 1045 34802895
Therapeutic response decreased 19.87 10.72 206 152785 29107 34774833
Enterovirus infection 19.80 10.72 23 152968 963 34802977
Haematemesis 19.78 10.72 59 152932 27652 34776288
Prostatic specific antigen increased 19.77 10.72 21 152970 14659 34789281
Glomerulonephritis rapidly progressive 19.73 10.72 19 152972 639 34803301
Limbic encephalitis 19.71 10.72 16 152975 427 34803513
Bronchopneumopathy 19.69 10.72 17 152974 495 34803445
Pathogen resistance 19.65 10.72 88 152903 9394 34794546
Cardiac failure 19.63 10.72 281 152710 90967 34712973
Gynaecomastia 19.62 10.72 10 152981 10170 34793770
Cutaneous nocardiosis 19.56 10.72 11 152980 156 34803784
Enterococcal bacteraemia 19.48 10.72 32 152959 1865 34802075
Torulopsis infection 19.45 10.72 6 152985 14 34803926
Labelled drug-drug interaction medication error 19.43 10.72 22 152969 14917 34789023
Underdose 19.37 10.72 19 152972 13761 34790179
Cerebral venous thrombosis 19.34 10.72 20 152971 734 34803206
Injection site mass 19.20 10.72 3 152988 6623 34797317
Therapy interrupted 19.12 10.72 19 152972 13678 34790262
C-reactive protein increased 19.12 10.72 338 152653 53760 34750180
Urticaria 19.04 10.72 381 152610 61996 34741944
Device leakage 19.00 10.72 3 152988 6572 34797368
Periumbilical abscess 18.98 10.72 8 152983 57 34803883
Shock haemorrhagic 18.94 10.72 99 152892 11255 34792685
Venoocclusive disease 18.92 10.72 40 152951 2827 34801113
Neuromyelitis optica spectrum disorder 18.81 10.72 10 152981 126 34803814
Meningitis cryptococcal 18.81 10.72 36 152955 2368 34801572
Fungal sepsis 18.79 10.72 21 152970 843 34803097
Growth retardation 18.74 10.72 31 152960 1817 34802123
Gastrointestinal fungal infection 18.73 10.72 11 152980 170 34803770
Cerebral aspergillosis 18.70 10.72 27 152964 1405 34802535
Fluid retention 18.65 10.72 58 152933 26829 34777111
Ageusia 18.59 10.72 11 152980 10297 34793643
Vaccination failure 18.59 10.72 24 152967 1122 34802818
Dyspepsia 18.57 10.72 90 152901 36642 34767298
Lung transplant rejection 18.52 10.72 20 152971 772 34803168
Tumefactive multiple sclerosis 18.50 10.72 7 152984 36 34803904
Hepatocellular injury 18.48 10.72 163 152828 22048 34781892
Skin discolouration 18.46 10.72 31 152960 17814 34786126
Injection site pruritus 18.43 10.72 4 152987 6979 34796961
Cystitis escherichia 18.40 10.72 11 152980 176 34803764
Peritoneal candidiasis 18.38 10.72 6 152985 18 34803922
Vitritis infective 18.38 10.72 6 152985 18 34803922
Secondary immunodeficiency 18.33 10.72 15 152976 405 34803535
Urinary retention 18.29 10.72 89 152902 36199 34767741
Chronic obstructive pulmonary disease 18.28 10.72 132 152859 48786 34755154
Nocturia 18.27 10.72 11 152980 10199 34793741
Enterococcal sepsis 18.25 10.72 29 152962 1643 34802297
Multiple sclerosis relapse 18.24 10.72 109 152882 13024 34790916
Lymphocytosis 18.24 10.72 37 152954 2540 34801400
Contraindicated product administered 18.18 10.72 42 152949 21439 34782501
Dysphagia 18.06 10.72 180 152811 62201 34741739
Pulmonary embolism 18.05 10.72 280 152711 89466 34714474
Foetal growth restriction 18.04 10.72 49 152942 4068 34799872
Irritability 18.03 10.72 52 152939 24638 34779302
Herpes simplex hepatitis 17.99 10.72 9 152982 99 34803841
Mucosal ulceration 17.99 10.72 22 152969 973 34802967
Hepatic cirrhosis 17.99 10.72 30 152961 17284 34786656
Blood sodium decreased 17.98 10.72 27 152964 16224 34787716
Immunoglobulin G4 related disease 17.95 10.72 10 152981 139 34803801
Hepatic artery thrombosis 17.92 10.72 12 152979 236 34803704
Mycobacterial infection 17.90 10.72 35 152956 2339 34801601
Brain herniation 17.86 10.72 48 152943 3960 34799980
Hypocalcaemia 17.86 10.72 51 152940 24238 34779702
Encephalitis 17.77 10.72 71 152920 7206 34796734
Myelocyte present 17.74 10.72 4 152987 0 34803940
Infective pulmonary exacerbation of cystic fibrosis 17.74 10.72 4 152987 6797 34797143
Agitation 17.73 10.72 163 152828 57236 34746704
Withdrawal syndrome 17.71 10.72 17 152974 12438 34791502
Organising pneumonia 17.65 10.72 62 152929 5917 34798023
Throat tightness 17.65 10.72 78 152913 8280 34795660
Encephalopathy 17.62 10.72 234 152757 35085 34768855
Abdominal abscess 17.61 10.72 49 152942 4126 34799814
Bordetella infection 17.61 10.72 9 152982 104 34803836
Cold type haemolytic anaemia 17.59 10.72 10 152981 145 34803795
Angina pectoris 17.56 10.72 74 152917 31289 34772651
Meningitis fungal 17.46 10.72 9 152982 106 34803834
Eye luxation 17.44 10.72 5 152986 8 34803932
Needle issue 17.39 10.72 3 152988 6162 34797778
Bradycardia 17.39 10.72 229 152762 75189 34728751
Bursitis infective 17.31 10.72 17 152974 586 34803354
Heart rate increased 17.26 10.72 292 152699 46051 34757889
Autoimmune haemolytic anaemia 17.25 10.72 51 152940 4445 34799495
Diabetic ketoacidosis 17.15 10.72 33 152958 17999 34785941
Graft infection 17.08 10.72 15 152976 447 34803493
Feeling hot 17.07 10.72 144 152847 19228 34784712
Herpes oesophagitis 17.06 10.72 10 152981 154 34803786
Bacterial test 17.06 10.72 10 152981 154 34803786
Drug dependence 16.97 10.72 52 152939 24165 34779775
Monocytopenia 16.92 10.72 8 152983 77 34803863
Exposure during pregnancy 16.88 10.72 9 152982 8925 34795015
Herpes virus infection 16.88 10.72 38 152953 2804 34801136
Gonococcal infection 16.83 10.72 7 152984 48 34803892
Arrhythmia 16.81 10.72 90 152901 35718 34768222
Immune thrombocytopenia 16.81 10.72 82 152909 9070 34794870
Escherichia sepsis 16.77 10.72 52 152939 4652 34799288
IgA nephropathy 16.77 10.72 24 152967 1239 34802701
Accelerated idioventricular rhythm 16.73 10.72 10 152981 160 34803780
Demodicidosis 16.71 10.72 11 152980 210 34803730
Vision blurred 16.71 10.72 125 152866 45838 34758102
Flushing 16.68 10.72 216 152775 32204 34771736
Blood glucose decreased 16.67 10.72 20 152971 13217 34790723
Muscle rigidity 16.60 10.72 13 152978 10505 34793435
Diastolic hypotension 16.59 10.72 7 152984 50 34803890
Megacolon 16.56 10.72 29 152962 1781 34802159
Klebsiella sepsis 16.55 10.72 31 152960 2006 34801934
Paranoia 16.55 10.72 17 152974 12051 34791889
Central nervous system lesion 16.55 10.72 64 152927 6399 34797541
Road traffic accident 16.54 10.72 32 152959 17418 34786522
Haptoglobin decreased 16.42 10.72 16 152975 546 34803394
Engraft failure 16.40 10.72 15 152976 472 34803468
Palpitations 16.38 10.72 105 152886 39881 34764059
White blood cells urine positive 16.35 10.72 24 152967 1268 34802672
Lymphangitis 16.35 10.72 16 152975 549 34803391
Hepatic function abnormal 16.33 10.72 279 152712 44084 34759856
Gastritis fungal 16.32 10.72 8 152983 84 34803856
Restlessness 16.28 10.72 57 152934 25425 34778515
Cytomegalovirus gastrointestinal infection 16.27 10.72 11 152980 220 34803720
Disseminated trichosporonosis 16.24 10.72 7 152984 53 34803887
Glucose-6-phosphate dehydrogenase deficiency 16.17 10.72 9 152982 125 34803815
Meningitis bacterial 16.14 10.72 24 152967 1283 34802657
Sudden death 16.11 10.72 26 152965 15175 34788765
Epistaxis 16.07 10.72 170 152821 58081 34745859
Cryptitis 16.05 10.72 11 152980 225 34803715
Diaphragmatic injury 16.04 10.72 9 152982 127 34803813
Femoral nerve palsy 16.02 10.72 7 152984 55 34803885
Toxoplasmosis 16.01 10.72 24 152967 1292 34802648
Angiocentric lymphoma 15.97 10.72 12 152979 285 34803655
Flatulence 15.96 10.72 44 152947 21154 34782786
Tardive dyskinesia 15.94 10.72 3 152988 5787 34798153
Epstein-Barr virus associated lymphoma 15.85 10.72 17 152974 651 34803289
Middle insomnia 15.85 10.72 5 152986 6797 34797143
Cardiomegaly 15.81 10.72 27 152964 15411 34788529
Blood lactate dehydrogenase increased 15.79 10.72 162 152829 22828 34781112
Stenotrophomonas infection 15.78 10.72 31 152960 2079 34801861
Rheumatoid arthritis 15.76 10.72 245 152746 37993 34765947
Episcleritis 15.70 10.72 10 152981 180 34803760
Listeriosis 15.69 10.72 21 152970 1017 34802923
Multi-organ disorder 15.69 10.72 23 152968 1214 34802726
Oral bacterial infection 15.68 10.72 6 152985 32 34803908
Papillitis 15.60 10.72 7 152984 59 34803881
Loss of consciousness 15.60 10.72 261 152730 82406 34721534
Sarcopenia 15.59 10.72 14 152977 430 34803510
Glycosylated haemoglobin increased 15.58 10.72 16 152975 11344 34792596
Mean cell haemoglobin increased 15.57 10.72 27 152964 1645 34802295
Arterial spasm 15.53 10.72 8 152983 94 34803846
Trichophytosis 15.52 10.72 12 152979 298 34803642
Urine ketone body present 15.51 10.72 22 152969 1126 34802814
Morganella infection 15.51 10.72 15 152976 507 34803433
Lymphocele 15.46 10.72 24 152967 1333 34802607
Pneumonia escherichia 15.43 10.72 14 152977 436 34803504
Fungal endocarditis 15.40 10.72 13 152978 367 34803573
Eosinophil percentage decreased 15.39 10.72 8 152983 96 34803844
Stupor 15.36 10.72 37 152954 2854 34801086
Urobilinogen urine increased 15.34 10.72 13 152978 369 34803571
Acinetobacter test positive 15.28 10.72 9 152982 140 34803800
Alopecia 15.21 10.72 55 152936 24300 34779640
Gastrointestinal ulcer 15.12 10.72 27 152964 1684 34802256
Herpes zoster meningoencephalitis 15.08 10.72 12 152979 311 34803629
Post procedural urine leak 15.05 10.72 9 152982 144 34803796
Blindness cortical 15.02 10.72 13 152978 380 34803560
Intravascular haemolysis 15.01 10.72 14 152977 452 34803488
Intestine transplant rejection 14.96 10.72 6 152985 37 34803903
Atypical mycobacterial infection 14.96 10.72 19 152972 874 34803066
Cardiac arrest 14.92 10.72 314 152677 95845 34708095
Tularaemia 14.90 10.72 8 152983 103 34803837
Urine leukocyte esterase positive 14.88 10.72 14 152977 457 34803483
Rhinovirus infection 14.85 10.72 47 152944 4252 34799688
Knee arthroplasty 14.82 10.72 7 152984 7437 34796503
Substance-induced psychotic disorder 14.81 10.72 27 152964 1711 34802229
Nervous system neoplasm 14.79 10.72 9 152982 149 34803791
Bacterial test positive 14.76 10.72 38 152953 3055 34800885
Aspiration 14.75 10.72 19 152972 12175 34791765
Cystitis viral 14.74 10.72 15 152976 540 34803400
Total lung capacity abnormal 14.73 10.72 9 152982 150 34803790
Lung neoplasm malignant 14.73 10.72 34 152957 17361 34786579
Disorientation 14.72 10.72 85 152906 33103 34770837
Superinfection bacterial 14.70 10.72 19 152972 889 34803051
Kidney rupture 14.70 10.72 10 152981 202 34803738
Hypoxia 14.70 10.72 330 152661 54765 34749175
Neuromyotonia 14.70 10.72 6 152985 39 34803901
Hepatic cancer 14.69 10.72 9 152982 8266 34795674
Bundle branch block left 14.66 10.72 4 152987 5975 34797965
Cataract subcapsular 14.65 10.72 13 152978 393 34803547
Pulmonary hypertension 14.61 10.72 45 152946 20879 34783061
Prescribed overdose 14.60 10.72 15 152976 10632 34793308
Skin exfoliation 14.58 10.72 66 152925 27366 34776574
Blood immunoglobulin M decreased 14.56 10.72 14 152977 470 34803470
Hepatic cytolysis 14.54 10.72 111 152880 14385 34789555
Bilirubin urine present 14.53 10.72 9 152982 154 34803786
IVth nerve paralysis 14.50 10.72 8 152983 109 34803831
Capnocytophaga infection 14.50 10.72 8 152983 109 34803831
Necrotising oesophagitis 14.49 10.72 15 152976 551 34803389
Acute kidney injury 14.46 10.72 1144 151847 303844 34500096
Urinary fistula 14.38 10.72 8 152983 111 34803829
Anti-neutrophil cytoplasmic antibody positive vasculitis 14.36 10.72 19 152972 910 34803030
Faeces discoloured 14.35 10.72 27 152964 14851 34789089
Multiple-drug resistance 14.34 10.72 53 152938 5186 34798754
Pleural mass 14.32 10.72 7 152984 73 34803867
Retinal detachment 14.31 10.72 54 152937 5337 34798603
Fibrin D dimer increased 14.29 10.72 46 152945 4198 34799742
Aspergillus test positive 14.29 10.72 14 152977 481 34803459
Mean cell haemoglobin concentration decreased 14.26 10.72 22 152969 1215 34802725
Heart rate irregular 14.20 10.72 118 152873 15689 34788251
Blood potassium increased 14.16 10.72 32 152959 16463 34787477
Capillaritis 14.13 10.72 8 152983 115 34803825
Wolff-Parkinson-White syndrome 14.13 10.72 10 152981 216 34803724
Exophthalmos 14.12 10.72 15 152976 568 34803372
Necrosis 14.11 10.72 56 152935 5667 34798273
Gastrointestinal perforation 14.05 10.72 43 152948 3820 34800120
Sexual dysfunction 14.05 10.72 5 152986 6298 34797642
Haematopoietic stem cell mobilisation 14.04 10.72 9 152982 164 34803776
Haemoperitoneum 14.01 10.72 27 152964 1785 34802155
Rib fracture 14.01 10.72 26 152965 14374 34789566
Blood immunoglobulin G decreased 14.00 10.72 24 152967 1449 34802491
Hip fracture 14.00 10.72 19 152972 11906 34792034
Coma 13.98 10.72 130 152861 45548 34758392
Pleuropericarditis 13.93 10.72 10 152981 221 34803719
Endocarditis 13.93 10.72 61 152930 6450 34797490
Dysarthria 13.91 10.72 92 152899 34690 34769250
Rectal haemorrhage 13.90 10.72 111 152880 40138 34763802
Drug level below therapeutic 13.89 10.72 55 152936 5560 34798380
Arterial rupture 13.87 10.72 14 152977 499 34803441
Urinary tract infection bacterial 13.82 10.72 28 152963 1920 34802020
Urinoma 13.81 10.72 10 152981 224 34803716
Septic pulmonary embolism 13.75 10.72 6 152985 47 34803893
Cytomegalovirus nephritis 13.72 10.72 8 152983 122 34803818
Nephritis 13.70 10.72 32 152959 2419 34801521
Acute hepatic failure 13.69 10.72 107 152884 13967 34789973
Emotional disorder 13.69 10.72 4 152987 5712 34798228
Immune reconstitution inflammatory syndrome 13.67 10.72 75 152916 8684 34795256
Abdominal infection 13.67 10.72 27 152964 1818 34802122
Abscess sterile 13.67 10.72 5 152986 23 34803917
Disseminated varicella zoster vaccine virus infection 13.64 10.72 6 152985 48 34803892
Chronic kidney disease 13.62 10.72 115 152876 41095 34762845
Hepatic artery occlusion 13.61 10.72 7 152984 82 34803858
Shock symptom 13.60 10.72 8 152983 124 34803816
Campylobacter gastroenteritis 13.59 10.72 18 152973 863 34803077
Arteriosclerosis coronary artery 13.56 10.72 21 152970 12464 34791476
Kaposi's sarcoma 13.56 10.72 18 152973 865 34803075
Interstitial lung disease 13.55 10.72 378 152613 64904 34739036
Dermatophytosis 13.51 10.72 10 152981 232 34803708
Hypocomplementaemia 13.50 10.72 5 152986 24 34803916
Syringe issue 13.49 10.72 4 152987 5660 34798280
Smooth muscle cell neoplasm 13.49 10.72 9 152982 176 34803764
Chimerism 13.47 10.72 10 152981 233 34803707
Familial periodic paralysis 13.46 10.72 7 152984 84 34803856
Haemoglobinuria 13.46 10.72 15 152976 600 34803340
Head injury 13.44 10.72 38 152953 18122 34785818
Weight increased 13.44 10.72 516 152475 92517 34711423
Vasculitis gastrointestinal 13.43 10.72 6 152985 50 34803890
Serratia infection 13.42 10.72 18 152973 874 34803066
Microsporidia infection 13.40 10.72 16 152975 690 34803250
Optic nerve compression 13.38 10.72 4 152987 8 34803932
Spermatozoa progressive motility decreased 13.38 10.72 8 152983 128 34803812
Steroid withdrawal syndrome 13.36 10.72 10 152981 236 34803704
Pneumonia influenzal 13.36 10.72 24 152967 1504 34802436
Abdominal distension 13.33 10.72 178 152813 58314 34745626
Chronic papillomatous dermatitis 13.33 10.72 6 152985 51 34803889
Liver function test 13.33 10.72 6 152985 51 34803889
Arteritis coronary 13.33 10.72 6 152985 51 34803889
Lower gastrointestinal haemorrhage 13.32 10.72 13 152978 9439 34794501
Presyncope 13.30 10.72 41 152950 19018 34784922
Atrioventricular block first degree 13.30 10.72 5 152986 6087 34797853
Panic attack 13.26 10.72 13 152978 9419 34794521
Cerebral venous sinus thrombosis 13.25 10.72 14 152977 527 34803413
Blastomycosis 13.17 10.72 13 152978 451 34803489
Post procedural bile leak 13.16 10.72 11 152980 306 34803634
Retinal scar 13.13 10.72 11 152980 307 34803633
Specific gravity urine decreased 13.11 10.72 7 152984 89 34803851
Haemolysis 13.11 10.72 70 152921 8024 34795916
Accident 13.10 10.72 3 152988 5044 34798896
Seizure 13.06 10.72 354 152637 104503 34699437
Aplasia 13.05 10.72 47 152944 4541 34799399
Pseudopolyposis 13.04 10.72 6 152985 54 34803886
Intestinal ulcer 13.01 10.72 18 152973 900 34803040
Product administration error 13.01 10.72 33 152958 16311 34787629
Type I hypersensitivity 12.96 10.72 22 152969 1317 34802623
Bacterial pyelonephritis 12.94 10.72 10 152981 248 34803692
Hypoaesthesia 12.93 10.72 190 152801 61254 34742686
Parkinsonism 12.92 10.72 10 152981 8128 34795812
Trichosporon infection 12.90 10.72 16 152975 718 34803222
Renal haemorrhage 12.88 10.72 23 152968 1434 34802506
Therapeutic product effect prolonged 12.84 10.72 10 152981 251 34803689
Meningoencephalitis herpetic 12.79 10.72 17 152974 818 34803122
Arthritis fungal 12.78 10.72 7 152984 94 34803846
Device related sepsis 12.75 10.72 36 152955 3057 34800883
Phaeochromocytoma 12.73 10.72 9 152982 194 34803746
Abnormal behaviour 12.72 10.72 61 152930 24908 34779032
Leishmaniasis 12.72 10.72 11 152980 321 34803619
Seronegative arthritis 12.72 10.72 19 152972 1020 34802920
Electrocardiogram abnormal 12.71 10.72 13 152978 9234 34794706
West Nile viral infection 12.68 10.72 16 152975 731 34803209
Uraemic encephalopathy 12.61 10.72 11 152980 325 34803615
Tumour lysis syndrome 12.58 10.72 122 152869 16937 34787003
Diffuse mesangial sclerosis 12.58 10.72 6 152985 59 34803881
Brain abscess 12.52 10.72 36 152955 3089 34800851
Herpes simplex meningoencephalitis 12.51 10.72 4 152987 11 34803929
Retching 12.50 10.72 7 152984 6754 34797186
Erosive duodenitis 12.50 10.72 25 152966 1699 34802241
Abdominal compartment syndrome 12.49 10.72 18 152973 935 34803005
Appendicitis 12.49 10.72 29 152962 14778 34789162
Mucosal disorder 12.48 10.72 25 152966 1701 34802239
Marrow hyperplasia 12.46 10.72 20 152971 1143 34802797
Abdominal pain 12.46 10.72 587 152404 163031 34640909
Acne fulminans 12.45 10.72 9 152982 201 34803739
Anuria 12.44 10.72 83 152908 10302 34793638
Tuberculosis 12.44 10.72 72 152919 8505 34795435
Dementia 12.36 10.72 26 152965 13722 34790218
Neutrophil count increased 12.34 10.72 122 152869 17024 34786916
Growth disorder 12.31 10.72 5 152986 32 34803908
Cardio-respiratory arrest 12.31 10.72 169 152822 55104 34748836
Ventricular extrasystoles 12.29 10.72 21 152970 11987 34791953
Type 2 diabetes mellitus 12.28 10.72 33 152958 15999 34787941
Ovarian cancer metastatic 12.25 10.72 4 152987 12 34803928
Peliosis hepatis 12.24 10.72 6 152985 63 34803877
Treatment failure 12.24 10.72 279 152712 46418 34757522
Pneumonia necrotising 12.23 10.72 16 152975 758 34803182
Malacoplakia gastrointestinal 12.22 10.72 7 152984 103 34803837
Adenomatous polyposis coli 12.19 10.72 8 152983 152 34803788
Removal of renal transplant 12.18 10.72 5 152986 33 34803907
Mood swings 12.17 10.72 10 152981 7891 34796049
Band neutrophil percentage increased 12.16 10.72 7 152984 104 34803836
Adrenal insufficiency 12.16 10.72 104 152887 13943 34789997
Osteonecrosis of jaw 12.12 10.72 39 152952 17850 34786090
Paraplegia 12.12 10.72 34 152957 2877 34801063
Chronic graft versus host disease in eye 12.10 10.72 7 152984 105 34803835
Pericarditis fungal 12.10 10.72 8 152983 154 34803786
Superinfection 12.08 10.72 31 152960 2488 34801452
Scedosporium infection 12.06 10.72 17 152974 865 34803075
Aplasia pure red cell 12.03 10.72 56 152935 6076 34797864
Hepatitis B 12.01 10.72 55 152936 5928 34798012
Microscopic polyangiitis 12.01 10.72 9 152982 213 34803727
Bacterial translocation 11.95 10.72 11 152980 349 34803591
Glomerulonephropathy 11.93 10.72 9 152982 215 34803725
Renal necrosis 11.92 10.72 8 152983 158 34803782
Biopsy lymph gland 11.92 10.72 6 152985 67 34803873
Demyelination 11.85 10.72 36 152955 3185 34800755
B-lymphocyte count increased 11.82 10.72 5 152986 36 34803904
Gallbladder rupture 11.80 10.72 14 152977 600 34803340
Herpes simplex colitis 11.79 10.72 4 152987 14 34803926
Investigation abnormal 11.79 10.72 13 152978 514 34803426
Pancreatitis 11.77 10.72 111 152880 38780 34765160
Arteriovenous fistula 11.76 10.72 19 152972 1092 34802848
Intestinal intraepithelial lymphocytes increased 11.75 10.72 8 152983 162 34803778
Retinal pigment epitheliopathy 11.72 10.72 9 152982 221 34803719
Encephalitis cytomegalovirus 11.72 10.72 14 152977 604 34803336
Nephrotic syndrome 11.72 10.72 63 152928 7240 34796700
Fungal disease carrier 11.70 10.72 10 152981 287 34803653
Conus medullaris syndrome 11.70 10.72 5 152986 37 34803903
Eschar 11.69 10.72 15 152976 697 34803243
Infection masked 11.69 10.72 6 152985 70 34803870
Muscle abscess 11.69 10.72 14 152977 606 34803334
Impaired work ability 11.67 10.72 8 152983 6922 34797018
Erythema infectiosum 11.66 10.72 8 152983 164 34803776
Fungal abscess central nervous system 11.66 10.72 7 152984 113 34803827
Donor specific antibody present 11.66 10.72 7 152984 113 34803827
Joint swelling 11.65 10.72 188 152803 59702 34744238
Inappropriate schedule of product administration 11.64 10.72 197 152794 62099 34741841
Pyelonephritis 11.64 10.72 56 152935 6159 34797781
Human herpesvirus 6 infection reactivation 11.62 10.72 8 152983 165 34803775
Therapy partial responder 11.61 10.72 77 152914 9539 34794401
Palatal ulcer 11.59 10.72 5 152986 38 34803902
Iron deficiency anaemia 11.58 10.72 17 152974 10312 34793628
Mental impairment 11.56 10.72 17 152974 10305 34793635
Pneumonia adenoviral 11.52 10.72 11 152980 366 34803574
Bilirubin conjugated increased 11.52 10.72 36 152955 3235 34800705
Reversible cerebral vasoconstriction syndrome 11.50 10.72 12 152979 445 34803495
Amoebic dysentery 11.48 10.72 5 152986 39 34803901
Ejection fraction decreased 11.47 10.72 44 152947 19110 34784830
Enthesopathy 11.47 10.72 3 152988 4610 34799330
Infective tenosynovitis 11.47 10.72 6 152985 73 34803867
Protein urine 11.46 10.72 17 152974 907 34803033
Gaze palsy 11.43 10.72 24 152967 1688 34802252
Haemorrhagic necrotic pancreatitis 11.41 10.72 8 152983 170 34803770
Renal artery perforation 11.38 10.72 4 152987 16 34803924
Carotid artery insufficiency 11.38 10.72 4 152987 16 34803924
Inadequate aseptic technique in use of product 11.38 10.72 4 152987 16 34803924
Pulmonary cavitation 11.37 10.72 17 152974 913 34803027
Cardiogenic shock 11.36 10.72 69 152922 26549 34777391
Herpes zoster cutaneous disseminated 11.33 10.72 8 152983 172 34803768
Eye infection toxoplasmal 11.32 10.72 9 152982 233 34803707
Body height below normal 11.32 10.72 9 152982 233 34803707
Lipoma 11.30 10.72 24 152967 1702 34802238
Delusion 11.27 10.72 24 152967 12611 34791329
Leukoplakia oral 11.26 10.72 6 152985 76 34803864
Nephrolithiasis 11.26 10.72 82 152909 30251 34773689
Macrophage activation 11.24 10.72 3 152988 3 34803937
Neonatal multi-organ failure 11.24 10.72 3 152988 3 34803937
Galactosaemia 11.24 10.72 3 152988 3 34803937
Status epilepticus 11.24 10.72 94 152897 12520 34791420
Peripheral vascular disorder 11.22 10.72 4 152987 5032 34798908
Poikiloderma 11.17 10.72 8 152983 176 34803764
Complications of transplanted heart 11.17 10.72 10 152981 306 34803634
Asthma 11.16 10.72 126 152865 42530 34761410
Tongue fungal infection 11.16 10.72 5 152986 42 34803898
Gastrooesophageal reflux disease 11.15 10.72 109 152882 37815 34766125
Swelling 11.14 10.72 125 152866 42241 34761699
Bacterial infection 11.13 10.72 119 152872 16944 34786996
Disseminated toxoplasmosis 11.12 10.72 6 152985 78 34803862
pH urine increased 11.12 10.72 6 152985 78 34803862
Sodium retention 11.12 10.72 6 152985 78 34803862
Infusion related hypersensitivity reaction 11.04 10.72 7 152984 125 34803815
Arterial thrombosis 11.02 10.72 22 152969 1493 34802447
Osteomyelitis blastomyces 11.00 10.72 4 152987 18 34803922
Gait inability 11.00 10.72 50 152941 20708 34783232
Cavernous sinus thrombosis 10.98 10.72 8 152983 181 34803759
Radiotherapy to brain 10.96 10.72 5 152986 44 34803896
Pulmonary fibrosis 10.95 10.72 126 152865 18270 34785670
Surgery 10.95 10.72 29 152962 14128 34789812
Plasma cell myeloma recurrent 10.92 10.72 3 152988 4462 34799478
Jejunal perforation 10.90 10.72 9 152982 246 34803694
Bronchomalacia 10.90 10.72 7 152984 128 34803812
Product dispensing error 10.89 10.72 7 152984 6267 34797673
Perforation 10.87 10.72 9 152982 247 34803693
Sopor 10.87 10.72 23 152968 12113 34791827
Infection in an immunocompromised host 10.84 10.72 14 152977 655 34803285
Inhibin B 10.83 10.72 4 152987 19 34803921
Neutropenic sepsis 10.80 10.72 28 152963 13739 34790201
Serratia sepsis 10.80 10.72 6 152985 83 34803857
Viral load abnormal 10.80 10.72 6 152985 83 34803857
Pancreas transplant rejection 10.79 10.72 8 152983 186 34803754
Nodular regenerative hyperplasia 10.79 10.72 17 152974 956 34802984
Cyanosis 10.79 10.72 94 152897 12670 34791270
Self-induced vomiting 10.78 10.72 3 152988 4 34803936
Back disorder 10.78 10.72 8 152983 6643 34797297
Aortic pseudoaneurysm 10.77 10.72 5 152986 46 34803894
Dysuria 10.76 10.72 72 152919 27080 34776860
Abscess fungal 10.75 10.72 9 152982 251 34803689
Synovitis 10.74 10.72 29 152962 14037 34789903
Hypoacusis 10.72 10.72 36 152955 16265 34787675
Coombs direct test positive 10.72 10.72 10 152981 323 34803617

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Off label use 1781.45 9.53 8447 352260 898768 78484913
Cytomegalovirus infection 1502.77 9.53 1366 359341 41278 79342403
Completed suicide 967.76 9.53 32 360675 245735 79137946
Product use in unapproved indication 883.76 9.53 2814 357893 247545 79136136
Drug ineffective for unapproved indication 850.57 9.53 1103 359604 50135 79333546
Infusion related reaction 825.44 9.53 2602 358105 227635 79156046
Blood pressure fluctuation 699.23 9.53 1160 359547 65985 79317696
Toxicity to various agents 614.23 9.53 601 360106 420939 78962742
Transplant rejection 589.32 9.53 573 360134 18864 79364817
Drug ineffective 571.74 9.53 7416 353291 1073497 78310184
Drug abuse 554.80 9.53 49 360658 162642 79221039
Aspergillus infection 553.26 9.53 550 360157 18611 79365070
Blood pressure diastolic abnormal 552.27 9.53 550 360157 18652 79365029
Bronchopulmonary aspergillosis 528.86 9.53 576 360131 21718 79361963
Cytomegalovirus viraemia 522.04 9.53 446 360261 12375 79371306
Death 521.77 9.53 1116 359591 565398 78818283
Blood pressure systolic abnormal 486.80 9.53 489 360218 16758 79366923
Oxygen saturation decreased 478.07 9.53 1476 359231 127571 79256110
Product dose omission issue 462.39 9.53 273 360434 247264 79136417
Pneumocystis jirovecii pneumonia 450.13 9.53 641 360066 31867 79351814
Posterior reversible encephalopathy syndrome 428.62 9.53 561 360146 25720 79357961
Multiple organ dysfunction syndrome 428.47 9.53 1357 359350 118889 79264792
Mucormycosis 423.38 9.53 332 360375 8137 79375544
Blood pressure systolic increased 418.75 9.53 932 359775 66054 79317627
Kidney transplant rejection 406.13 9.53 351 360356 9895 79373786
Post transplant lymphoproliferative disorder 405.14 9.53 368 360339 11096 79372585
Blood pressure increased 402.36 9.53 1957 358750 209403 79174278
Thrombotic microangiopathy 395.21 9.53 472 360235 19697 79363984
Fall 389.48 9.53 1035 359672 486594 78897087
Lymphocyte count decreased 386.53 9.53 735 359972 46554 79337127
Haemophagocytic lymphohistiocytosis 343.54 9.53 458 360249 21379 79362302
Epstein-Barr virus infection 342.85 9.53 373 360334 14043 79369638
Respiratory failure 336.31 9.53 1664 359043 179247 79204434
Urine abnormality 334.79 9.53 286 360421 7933 79375748
Intentional overdose 328.10 9.53 45 360662 105915 79277766
Heart rate decreased 313.90 9.53 860 359847 69456 79314225
Throat irritation 304.95 9.53 612 360095 40334 79343347
Complications of transplanted kidney 304.14 9.53 243 360464 6123 79377558
Polyomavirus-associated nephropathy 304.01 9.53 231 360476 5396 79378285
Strongyloidiasis 303.40 9.53 200 360507 3698 79379983
Graft versus host disease 303.24 9.53 357 360350 14669 79369012
BK virus infection 292.43 9.53 273 360434 8531 79375150
Pneumatosis intestinalis 286.21 9.53 235 360472 6162 79377519
Graft versus host disease in gastrointestinal tract 281.25 9.53 232 360475 6124 79377557
Nocardiosis 265.41 9.53 214 360493 5465 79378216
Steroid diabetes 258.68 9.53 174 360533 3332 79380349
Cytomegalovirus infection reactivation 251.25 9.53 250 360457 8466 79375215
Septic shock 250.90 9.53 1161 359546 121640 79262041
Injection site pain 242.56 9.53 143 360564 129695 79253986
Urine leukocyte esterase positive 241.23 9.53 177 360530 3914 79379767
Cytomegalovirus test positive 238.28 9.53 205 360502 5742 79377939
Overdose 236.50 9.53 291 360416 183915 79199766
Adenovirus infection 233.79 9.53 237 360470 8210 79375471
Red blood cells urine positive 229.78 9.53 186 360521 4777 79378904
Enterococcal infection 228.96 9.53 317 360390 15343 79368338
Cardiac failure congestive 228.62 9.53 185 360522 142217 79241464
Blood pressure diastolic decreased 227.84 9.53 454 360253 29762 79353919
Confusional state 214.66 9.53 729 359978 317268 79066413
Pseudomonas infection 213.29 9.53 358 360349 20545 79363136
Klebsiella infection 213.22 9.53 307 360400 15413 79368268
White blood cells urine positive 208.78 9.53 192 360515 5883 79377798
Myocardial infarction 208.10 9.53 319 360388 183810 79199871
Human herpesvirus 6 infection 206.85 9.53 181 360526 5189 79378492
Hospitalisation 205.98 9.53 84 360623 94152 79289529
Nausea 204.65 9.53 3075 357632 954121 78429560
Dehydration 203.71 9.53 519 360188 247668 79136013
Vomiting 203.62 9.53 1978 358729 663850 78719831
Graft versus host disease in skin 203.02 9.53 189 360518 5884 79377797
Urinary sediment present 202.01 9.53 132 360575 2403 79381278
Syncope 194.18 9.53 320 360387 179129 79204552
Synovitis 193.60 9.53 238 360469 150496 79233185
Pneumomediastinum 192.52 9.53 148 360559 3519 79380162
Dizziness 192.36 9.53 1493 359214 524948 78858733
Diarrhoea 190.02 9.53 2823 357884 877666 78506015
Acute graft versus host disease in skin 188.86 9.53 202 360505 7456 79376225
Candida infection 188.37 9.53 485 360222 37729 79345952
Lymphopenia 187.35 9.53 422 360285 30135 79353546
Crystal urine present 185.76 9.53 118 360589 2042 79381639
Progressive multifocal leukoencephalopathy 185.65 9.53 334 360373 20266 79363415
Wrong technique in product usage process 185.53 9.53 52 360655 73823 79309858
Delayed graft function 185.13 9.53 142 360565 3365 79380316
Disseminated intravascular coagulation 180.92 9.53 459 360248 35383 79348298
Suicide attempt 179.52 9.53 75 360632 82857 79300824
Pneumonia cytomegaloviral 178.50 9.53 161 360546 4808 79378873
Lymphocyte percentage decreased 176.34 9.53 160 360547 4816 79378865
Acute respiratory distress syndrome 173.31 9.53 515 360192 43552 79340129
Neutrophil percentage increased 172.54 9.53 154 360553 4535 79379146
Alopecia 171.75 9.53 508 360199 230847 79152834
Cystitis haemorrhagic 167.24 9.53 207 360500 8965 79374716
Heart rate increased 165.57 9.53 1023 359684 119701 79263980
Hypoglycaemia 163.03 9.53 132 360575 101462 79282219
Erythema 160.70 9.53 1630 359077 221660 79162021
Fatigue 158.96 9.53 3109 357598 926618 78457063
Cushingoid 157.43 9.53 205 360502 9347 79374334
Urine analysis abnormal 155.56 9.53 169 360538 6351 79377330
Glossodynia 155.20 9.53 143 360564 103194 79280487
Immunosuppressant drug level increased 153.89 9.53 197 360510 8830 79374851
COVID-19 151.75 9.53 1226 359481 156448 79227233
Injection site erythema 149.05 9.53 84 360623 78113 79305568
Abdominal discomfort 148.70 9.53 606 360101 250121 79133560
Orthostatic hypotension 147.77 9.53 36 360671 56128 79327553
Multiple sclerosis relapse 141.47 9.53 498 360209 46035 79337646
Rebound effect 141.37 9.53 169 360538 7057 79376624
Serotonin syndrome 139.65 9.53 19 360688 45008 79338673
Drug intolerance 138.73 9.53 668 360039 263451 79120230
Acute graft versus host disease in intestine 137.48 9.53 127 360580 3914 79379767
Liver transplant rejection 136.34 9.53 115 360592 3133 79380548
Swelling 136.02 9.53 512 360195 216199 79167482
Cytomegalovirus chorioretinitis 135.72 9.53 145 360562 5345 79378336
Acute graft versus host disease 135.62 9.53 197 360510 9970 79373711
Drug interaction 135.40 9.53 1213 359494 413970 78969711
Cerebrovascular accident 134.22 9.53 316 360391 154976 79228705
Secondary immunodeficiency 132.66 9.53 113 360594 3121 79380560
Mycobacterium chelonae infection 130.86 9.53 100 360607 2356 79381325
Cytomegalovirus colitis 130.66 9.53 132 360575 4553 79379128
Decreased appetite 130.13 9.53 960 359747 341458 79042223
Flushing 128.66 9.53 760 359947 87508 79296173
Constipation 128.01 9.53 753 359954 282297 79101384
Peripheral swelling 128.00 9.53 706 360001 268911 79114770
Contraindicated product administered 127.22 9.53 332 360375 157206 79226475
Drug effective for unapproved indication 126.80 9.53 146 360561 5855 79377826
Blood pressure diastolic increased 124.98 9.53 231 360476 14311 79369370
Hyponatraemia 124.51 9.53 401 360306 177447 79206234
Varicella zoster virus infection 123.63 9.53 125 360582 4316 79379365
Oedema peripheral 123.42 9.53 654 360053 251634 79132047
Irritable bowel syndrome 122.79 9.53 64 360643 62177 79321504
Sleep disorder due to general medical condition, insomnia type 120.45 9.53 25 360682 43531 79340150
Parvovirus B19 infection 120.23 9.53 78 360629 1402 79382279
Acinetobacter infection 120.03 9.53 100 360607 2677 79381004
Red cell distribution width increased 119.72 9.53 233 360474 15009 79368672
Loss of personal independence in daily activities 117.50 9.53 176 360531 102404 79281277
Escherichia infection 116.28 9.53 254 360453 17763 79365918
Sedation 115.46 9.53 45 360662 51850 79331831
Enterobacter infection 115.45 9.53 122 360585 4440 79379241
International normalised ratio increased 114.95 9.53 128 360579 84593 79299088
Ear pruritus 114.87 9.53 116 360591 3999 79379682
Wound 112.34 9.53 222 360485 115957 79267724
Intentional product use issue 112.05 9.53 1116 359591 150996 79232685
Osteonecrosis 111.62 9.53 352 360355 30743 79352938
Muscle injury 111.57 9.53 40 360667 48521 79335160
Infection reactivation 111.37 9.53 94 360613 2563 79381118
Intentional product misuse 111.23 9.53 161 360546 95004 79288677
Systemic mycosis 111.10 9.53 94 360613 2572 79381109
Arthropathy 109.46 9.53 421 360286 176690 79206991
Pulmonary mucormycosis 108.64 9.53 67 360640 1098 79382583
Bacterial test 108.15 9.53 68 360639 1155 79382526
Accidental exposure to product 107.90 9.53 9 360698 31313 79352368
Asthenia 107.75 9.53 1647 359060 510042 78873639
Pyrexia 107.39 9.53 3913 356794 674796 78708885
Chorioretinopathy 106.23 9.53 85 360622 2146 79381535
Coronary artery disease 105.12 9.53 85 360622 65389 79318292
Blood urine present 104.64 9.53 270 360437 21027 79362654
Leukopenia 104.07 9.53 891 359816 115622 79268059
Injection site swelling 103.00 9.53 42 360665 47090 79336591
Rheumatoid arthritis 102.97 9.53 1416 359291 207054 79176627
Rhabdomyolysis 102.38 9.53 194 360513 102937 79280744
Bacterial test positive 101.79 9.53 146 360561 7303 79376378
Hypertension 100.54 9.53 2077 358630 328915 79054766
Myopathy 100.32 9.53 260 360447 20303 79363378
Drug resistance 99.74 9.53 417 360290 41796 79341885
Device expulsion 99.49 9.53 4 360703 25857 79357824
Accidental overdose 99.12 9.53 28 360679 39553 79344128
Herpes simplex 99.02 9.53 189 360518 11998 79371683
Disease recurrence 99.01 9.53 429 360278 43680 79340001
Acute graft versus host disease in liver 97.02 9.53 76 360631 1859 79381822
Intentional self-injury 95.22 9.53 16 360691 32403 79351278
Protein urine present 95.03 9.53 167 360540 9945 79373736
Pulmonary nocardiosis 94.18 9.53 64 360643 1247 79382434
Hyperglycaemia 93.88 9.53 592 360115 69743 79313938
Staphylococcal sepsis 93.22 9.53 206 360501 14520 79369161
Urine ketone body present 93.18 9.53 97 360610 3468 79380213
Discomfort 93.03 9.53 276 360431 125341 79258340
Pulmonary alveolar haemorrhage 92.26 9.53 177 360530 11280 79372401
Pharyngeal paraesthesia 91.57 9.53 85 360622 2636 79381045
Hand deformity 90.94 9.53 210 360497 103709 79279972
General physical health deterioration 90.56 9.53 802 359905 274436 79109245
Diffuse alveolar damage 90.53 9.53 96 360611 3508 79380173
Epstein-Barr virus associated lymphoproliferative disorder 90.35 9.53 95 360612 3437 79380244
Transient ischaemic attack 90.25 9.53 64 360643 52631 79331050
Pericarditis 90.13 9.53 212 360495 104024 79279657
Cytomegalovirus enteritis 89.37 9.53 52 360655 762 79382919
Temperature regulation disorder 89.36 9.53 121 360586 5732 79377949
Rhinocerebral mucormycosis 89.00 9.53 57 360650 1001 79382680
Stomatitis 88.02 9.53 353 360354 146404 79237277
COVID-19 pneumonia 87.90 9.53 309 360398 28540 79355141
Viraemia 87.74 9.53 85 360622 2784 79380897
Pain 87.42 9.53 2470 358237 701332 78682349
Nephropathy toxic 86.40 9.53 245 360462 20174 79363507
Product prescribing error 85.59 9.53 48 360659 44765 79338916
Disseminated mucormycosis 85.36 9.53 49 360658 699 79382982
Renal transplant failure 85.19 9.53 70 360637 1837 79381844
Dyspnoea 85.09 9.53 3097 357610 853928 78529753
Viral haemorrhagic cystitis 84.51 9.53 72 360635 1989 79381692
Bacterial sepsis 84.42 9.53 141 360566 8057 79375624
Cryptococcosis 84.14 9.53 91 360616 3402 79380279
Injection site pruritus 84.11 9.53 43 360664 42240 79341441
Systemic lupus erythematosus 83.49 9.53 275 360432 120874 79262807
Focal segmental glomerulosclerosis 82.60 9.53 88 360619 3233 79380448
Feeling hot 82.36 9.53 507 360200 59227 79324454
Systemic candida 82.36 9.53 125 360582 6581 79377100
Mycobacterium abscessus infection 81.53 9.53 57 360650 1165 79382516
Sopor 81.46 9.53 24 360683 32986 79350695
Contusion 81.16 9.53 371 360336 148405 79235276
Injection site bruising 81.11 9.53 42 360665 40960 79342721
Therapy non-responder 80.91 9.53 703 360004 91602 79292079
Multiple sclerosis 80.67 9.53 253 360454 22029 79361652
Intensive care unit acquired weakness 80.23 9.53 68 360639 1865 79381816
Cytokine release syndrome 79.94 9.53 349 360358 35649 79348032
Haemoglobin urine present 79.22 9.53 51 360656 904 79382777
Culture urine positive 79.11 9.53 99 360608 4336 79379345
Chronic allograft nephropathy 78.95 9.53 64 360643 1647 79382034
Serum sickness 78.82 9.53 90 360617 3576 79380105
Immunodeficiency 78.66 9.53 247 360460 21521 79362160
Anaphylactic shock 78.43 9.53 347 360360 35649 79348032
Monocyte percentage increased 78.15 9.53 70 360637 2071 79381610
Pseudomonal sepsis 77.12 9.53 116 360591 6058 79377623
JC virus infection 76.31 9.53 91 360616 3790 79379891
Pneumocystis jirovecii infection 76.10 9.53 79 360628 2815 79380866
Reversible cerebral vasoconstriction syndrome 76.02 9.53 81 360626 2976 79380705
Sepsis 75.10 9.53 1670 359037 267758 79115923
Cytomegalovirus enterocolitis 74.46 9.53 61 360646 1594 79382087
Acute kidney injury 74.16 9.53 1786 358921 517618 78866063
Diabetes mellitus 73.99 9.53 607 360100 77783 79305898
Neutrophil count increased 73.88 9.53 296 360411 29100 79354581
Full blood count abnormal 73.56 9.53 46 360661 40428 79343253
Specific gravity urine decreased 73.11 9.53 47 360660 831 79382850
Substance-induced psychotic disorder 72.53 9.53 83 360624 3306 79380375
Respiratory rate increased 72.52 9.53 239 360468 21361 79362320
Pemphigus 72.15 9.53 221 360486 99361 79284320
Therapy interrupted 71.69 9.53 26 360681 31315 79352366
Device malfunction 71.62 9.53 7 360700 21441 79362240
Gastroenteritis norovirus 71.48 9.53 79 360628 3027 79380654
Diffuse large B-cell lymphoma 71.38 9.53 165 360542 11984 79371697
Product quality issue 71.36 9.53 32 360675 33908 79349773
Malignant neoplasm progression 71.30 9.53 344 360363 135646 79248035
Granulomatosis with polyangiitis 71.29 9.53 76 360631 2794 79380887
Febrile bone marrow aplasia 71.26 9.53 172 360535 12848 79370833
Poisoning 70.93 9.53 14 360693 25258 79358423
Fungal infection 70.46 9.53 374 360333 41374 79342307
C-reactive protein abnormal 70.19 9.53 69 360638 48298 79335383
Lupus nephritis 70.08 9.53 77 360630 2931 79380750
Osteonecrosis of jaw 69.53 9.53 56 360651 43170 79340511
Vasculitis 68.98 9.53 260 360447 24842 79358839
Dural arteriovenous fistula 68.94 9.53 21 360686 44 79383637
Central nervous system infection 68.86 9.53 54 360653 1323 79382358
Staphylococcal infection 68.31 9.53 475 360232 57820 79325861
Adverse event 68.28 9.53 104 360603 60110 79323571
Depressed level of consciousness 68.25 9.53 217 360490 96435 79287246
Hypophagia 67.84 9.53 63 360644 45304 79338377
Suicidal ideation 67.82 9.53 153 360554 76187 79307494
Chronic graft versus host disease 67.66 9.53 115 360592 6666 79377015
Hypogammaglobulinaemia 67.59 9.53 168 360539 12783 79370898
Bacteraemia 67.46 9.53 311 360396 32513 79351168
Lethargy 67.38 9.53 169 360538 81123 79302558
Anti-cyclic citrullinated peptide antibody positive 67.26 9.53 175 360532 82968 79300713
Device issue 66.37 9.53 20 360687 27088 79356593
Rheumatoid factor positive 66.28 9.53 105 360602 59734 79323947
Opportunistic infection 66.11 9.53 74 360633 2876 79380805
Proteinuria 66.10 9.53 307 360400 32195 79351486
Human herpesvirus 8 infection 65.72 9.53 50 360657 1170 79382511
Chest discomfort 65.03 9.53 930 359777 137114 79246567
Helicobacter infection 64.98 9.53 136 360571 69568 79314113
Adverse drug reaction 64.92 9.53 126 360581 66266 79317415
Polyomavirus viraemia 64.67 9.53 57 360650 1650 79382031
Unresponsive to stimuli 64.57 9.53 95 360612 55693 79327988
Renal tubular atrophy 64.44 9.53 59 360648 1797 79381884
Immunosuppressant drug level decreased 64.36 9.53 61 360646 1943 79381738
Psoriatic arthropathy 64.00 9.53 163 360544 77836 79305845
Duodenal ulcer perforation 63.58 9.53 127 360580 66084 79317597
Transplant failure 63.47 9.53 91 360616 4550 79379131
Medication error 63.09 9.53 135 360572 68507 79315174
Central nervous system fungal infection 63.07 9.53 34 360673 426 79383255
Neuroleptic malignant syndrome 62.80 9.53 23 360684 27536 79356145
Necrotising retinitis 62.64 9.53 49 360658 1196 79382485
Therapy cessation 62.53 9.53 47 360660 37515 79346166
Systemic inflammatory response syndrome 62.25 9.53 151 360556 11314 79372367
Premature delivery 61.97 9.53 240 360467 23227 79360454
Graft versus host disease in liver 61.37 9.53 56 360651 1698 79381983
Memory impairment 61.31 9.53 278 360429 111456 79272225
Bacterial infection 61.08 9.53 292 360415 30988 79352693
Human bocavirus infection 59.87 9.53 39 360668 706 79382975
Electric shock 59.84 9.53 50 360657 1344 79382337
Body temperature decreased 59.14 9.53 295 360412 31850 79351831
Lower respiratory tract infection 58.75 9.53 343 360364 128877 79254804
Red blood cell sedimentation rate abnormal 58.03 9.53 12 360695 20951 79362730
Candida sepsis 57.97 9.53 64 360643 2449 79381232
Coeliac disease 57.94 9.53 146 360561 11205 79372476
Pneumonia cryptococcal 57.64 9.53 51 360656 1484 79382197
Stenotrophomonas infection 57.60 9.53 78 360629 3695 79379986
Nitrite urine present 57.43 9.53 46 360661 1163 79382518
Muscle spasms 57.05 9.53 510 360197 174220 79209461
Full blood count decreased 56.84 9.53 25 360682 26794 79356887
Coma 56.68 9.53 248 360459 100401 79283280
Psoriasis 56.58 9.53 211 360496 89376 79294305
Respiratory arrest 56.46 9.53 109 360598 57441 79326240
Pleocytosis 56.42 9.53 49 360658 1390 79382291
Prostate cancer 56.19 9.53 41 360666 33227 79350454
Pain in extremity 56.03 9.53 1239 359468 363299 79020382
Atrial fibrillation 56.02 9.53 598 360109 197288 79186393
Infective aneurysm 55.82 9.53 42 360665 966 79382715
Glomerulonephritis 55.52 9.53 73 360634 3360 79380321
Corynebacterium infection 55.39 9.53 47 360660 1291 79382390
Perinephric abscess 55.39 9.53 26 360681 237 79383444
Food allergy 55.01 9.53 139 360568 10685 79372996
Hyperkalaemia 54.53 9.53 299 360408 114099 79269582
Specific gravity urine increased 54.45 9.53 31 360676 435 79383246
Thrombocytopenia 54.36 9.53 1578 359129 263681 79120000
Cytomegalovirus oesophagitis 54.36 9.53 37 360670 723 79382958
Ureaplasma infection 54.30 9.53 42 360665 1008 79382673
Toxoplasmosis 54.28 9.53 64 360643 2633 79381048
Gastrointestinal disorder 54.17 9.53 327 360380 121878 79261803
Plasma cell myeloma 53.89 9.53 99 360608 53160 79330521
Intra-abdominal pressure increased 53.84 9.53 26 360681 254 79383427
Knee arthroplasty 53.71 9.53 70 360637 43178 79340503
Loss of consciousness 53.60 9.53 493 360214 167450 79216231
Renal tubular necrosis 53.51 9.53 240 360467 24799 79358882
C-reactive protein increased 53.30 9.53 850 359857 128177 79255504
Chest pain 53.22 9.53 927 359780 281377 79102304
Necrosis ischaemic 52.91 9.53 42 360665 1048 79382633
Pneumonia acinetobacter 52.66 9.53 23 360684 174 79383507
Sedation complication 52.62 9.53 5 360702 15664 79368017
Herpes zoster 52.07 9.53 647 360060 92436 79291245
Oral herpes 51.96 9.53 254 360453 27200 79356481
Immune thrombocytopenia 51.93 9.53 188 360519 17617 79366064
Haemolytic uraemic syndrome 51.92 9.53 81 360626 4368 79379313
Glomerulosclerosis 51.84 9.53 42 360665 1080 79382601
Anaemia 51.79 9.53 1575 359132 443440 78940241
Injection site haemorrhage 51.59 9.53 31 360676 27839 79355842
Myalgia 51.34 9.53 564 360143 185077 79198604
Injection site mass 51.06 9.53 14 360693 20170 79363511
Injection site reaction 50.97 9.53 107 360600 54678 79329003
Nightmare 50.40 9.53 27 360680 25834 79357847
Epstein-Barr virus infection reactivation 50.39 9.53 52 360655 1840 79381841
Disseminated cryptococcosis 49.92 9.53 51 360656 1783 79381898
Pulmonary haemorrhage 49.55 9.53 163 360544 14554 79369127
Treatment noncompliance 49.55 9.53 101 360606 52167 79331514
Sleep disorder due to a general medical condition 49.46 9.53 4 360703 14273 79369408
Haemolytic anaemia 49.32 9.53 185 360522 17635 79366046
Folliculitis 49.18 9.53 111 360596 55269 79328412
Sleep disorder 48.92 9.53 210 360497 85467 79298214
Epstein-Barr viraemia 48.88 9.53 55 360652 2150 79381531
Abdominal pain upper 48.85 9.53 715 359992 223104 79160577
Drug withdrawal syndrome 48.70 9.53 51 360656 34667 79349014
Encephalitis 48.38 9.53 162 360545 14598 79369083
Blood thyroid stimulating hormone decreased 48.12 9.53 90 360617 5626 79378055
Labelled drug-drug interaction medication error 48.11 9.53 33 360674 27617 79356064
Listeriosis 47.97 9.53 55 360652 2195 79381486
West Nile viral infection 47.34 9.53 38 360669 964 79382717
Hallucination 47.24 9.53 213 360494 85532 79298149
Red blood cells urine 46.97 9.53 33 360674 680 79383001
Blood calcium decreased 46.62 9.53 45 360662 31774 79351907
Monocyte count increased 46.17 9.53 129 360578 10532 79373149
Surgery 46.11 9.53 48 360659 32718 79350963
Demyelination 46.08 9.53 108 360599 7915 79375766
Amoebic colitis 46.01 9.53 18 360689 99 79383582
Brain abscess 45.71 9.53 81 360626 4855 79378826
Device difficult to use 45.68 9.53 4 360703 13381 79370300
Feeling abnormal 45.49 9.53 480 360227 158719 79224962
Aggression 45.36 9.53 102 360605 50856 79332825
Bone pain 45.33 9.53 117 360590 55625 79328056
Herpes virus infection 45.06 9.53 99 360608 6950 79376731
Pneumonia bacterial 44.91 9.53 190 360517 19141 79364540
Status epilepticus 44.79 9.53 228 360479 24813 79358868
Central nervous system viral infection 44.72 9.53 18 360689 108 79383573
Mobility decreased 44.68 9.53 346 360361 121829 79261852
Quadriplegia 44.66 9.53 65 360642 3295 79380386
Penicillium infection 44.57 9.53 23 360684 262 79383419
Malaise 44.51 9.53 1788 358919 488081 78895600
Disseminated tuberculosis 44.49 9.53 73 360634 4110 79379571
Acute myocardial infarction 44.48 9.53 188 360519 76848 79306833
Intervertebral discitis 44.42 9.53 79 360628 4749 79378932
Blood immunoglobulin M decreased 44.26 9.53 41 360666 1268 79382413
Ureteric stenosis 44.00 9.53 42 360665 1350 79382331
Disseminated strongyloidiasis 43.85 9.53 22 360685 235 79383446
Cardiac failure 43.78 9.53 468 360239 154374 79229307
Multiple-drug resistance 43.61 9.53 112 360595 8696 79374985
Osteomyelitis fungal 43.60 9.53 23 360684 275 79383406
Pneumonia pseudomonal 43.58 9.53 88 360619 5823 79377858
Kidney fibrosis 43.56 9.53 66 360641 3469 79380212
Large intestine perforation 43.49 9.53 155 360552 14412 79369269
Skin striae 43.41 9.53 48 360659 1840 79381841
Fungaemia 43.37 9.53 76 360631 4515 79379166
Disseminated varicella zoster virus infection 43.34 9.53 30 360677 603 79383078
Pneumonia fungal 43.11 9.53 130 360577 11080 79372601
Underdose 42.89 9.53 52 360655 33099 79350582
Haemodynamic instability 42.86 9.53 174 360533 17208 79366473
Encephalitis cytomegalovirus 42.77 9.53 38 360669 1112 79382569
Epstein-Barr virus associated lymphoma 42.54 9.53 37 360670 1052 79382629
Therapeutic product effect decreased 42.12 9.53 506 360201 163357 79220324
Cerebral aspergillosis 41.88 9.53 46 360661 1750 79381931
Pneumoretroperitoneum 41.67 9.53 19 360688 161 79383520
B-lymphocyte count decreased 41.57 9.53 41 360666 1373 79382308
Product storage error 41.52 9.53 11 360696 16215 79367466
Cardiac disorder 41.44 9.53 155 360552 65602 79318079
Aplasia 41.40 9.53 102 360605 7718 79375963
Apoptosis 41.25 9.53 27 360680 493 79383188
Cardio-respiratory arrest 41.24 9.53 304 360403 108206 79275475
Gastrooesophageal reflux disease 41.10 9.53 289 360418 103957 79279724
Blister 41.09 9.53 344 360363 119132 79264549
Osmotic demyelination syndrome 41.05 9.53 42 360665 1471 79382210
Injection site rash 40.88 9.53 15 360692 17939 79365742
Pain in jaw 40.58 9.53 93 360614 46058 79337623
Nephrotic syndrome 40.56 9.53 127 360580 11047 79372634
Poor venous access 40.33 9.53 176 360531 17973 79365708
Pedal pulse abnormal 40.31 9.53 19 360688 175 79383506
Abscess bacterial 40.19 9.53 32 360675 802 79382879
Respiratory distress 40.05 9.53 422 360285 57917 79325764
Injection site warmth 39.92 9.53 9 360698 14798 79368883
Pulmonary hypertension 39.81 9.53 100 360607 47980 79335701
Venoocclusive disease 39.75 9.53 73 360634 4500 79379181
Drug hypersensitivity 39.56 9.53 1039 359668 297877 79085804
Extrapyramidal disorder 39.55 9.53 27 360680 22652 79361029
Phaeohyphomycosis 39.53 9.53 37 360670 1160 79382521
Oral pruritus 39.51 9.53 52 360655 2396 79381285
Electrocardiogram QT prolonged 39.46 9.53 243 360464 90143 79293538
Needle issue 39.39 9.53 6 360701 13062 79370619
Segmental diverticular colitis 39.12 9.53 18 360689 156 79383525
Hepatocellular injury 38.88 9.53 357 360350 47236 79336445
Cutaneous mucormycosis 38.79 9.53 19 360688 192 79383489
Rash erythematous 38.78 9.53 416 360291 57353 79326328
Neuropathy peripheral 38.39 9.53 431 360276 140874 79242807
Respiratory depression 38.29 9.53 41 360666 27589 79356092
Pathogen resistance 38.13 9.53 147 360560 14195 79369486
Steroid withdrawal syndrome 37.63 9.53 29 360678 692 79382989
Enterococcus test positive 37.58 9.53 47 360660 2057 79381624
Shock haemorrhagic 37.54 9.53 185 360522 19875 79363806
Mycoplasma infection 37.44 9.53 30 360677 759 79382922
Somnolence 37.33 9.53 810 359897 238171 79145510
Neurological decompensation 37.30 9.53 77 360630 5176 79378505
Partial seizures 37.28 9.53 107 360600 8871 79374810
Swollen tongue 37.25 9.53 86 360621 42484 79341197
Herpes simplex colitis 37.13 9.53 12 360695 33 79383648
Bilirubin urine present 37.08 9.53 22 360685 335 79383346
Urinary casts 37.06 9.53 36 360671 1183 79382498
Obstructive airways disorder 36.97 9.53 53 360654 31406 79352275
Product substitution issue 36.84 9.53 23 360684 20233 79363448
Cytomegalovirus gastrointestinal infection 36.79 9.53 25 360682 487 79383194
Thyroxine free increased 36.74 9.53 36 360671 1196 79382485
Incorrect dose administered 36.67 9.53 200 360507 76430 79307251
Symptom masked 36.65 9.53 38 360669 1352 79382329
Rectal haemorrhage 36.59 9.53 199 360508 76101 79307580
Incision site pain 36.54 9.53 54 360653 2776 79380905
Tardive dyskinesia 36.51 9.53 3 360704 10568 79373113
Scedosporium infection 36.47 9.53 39 360668 1439 79382242
Haematemesis 36.43 9.53 118 360589 52146 79331535
Torsade de pointes 36.43 9.53 21 360686 19291 79364390
Rhinovirus infection 36.19 9.53 98 360609 7855 79375826
Clostridium difficile colitis 36.04 9.53 260 360447 32023 79351658
Cystitis bacterial 35.85 9.53 28 360679 682 79382999
Heart rate irregular 35.80 9.53 262 360445 32417 79351264
Enthesopathy 35.75 9.53 5 360702 11603 79372078
Oesophageal candidiasis 35.54 9.53 107 360600 9111 79374570
Central nervous system lesion 35.53 9.53 137 360570 13231 79370450
Cytomegalovirus hepatitis 35.49 9.53 29 360678 755 79382926
Band sensation 35.36 9.53 29 360678 759 79382922
Pneumothorax 35.09 9.53 234 360473 28089 79355592
Impaired healing 35.04 9.53 242 360465 87413 79296268
Intestinal perforation 34.99 9.53 164 360543 17262 79366419
Lung abscess 34.93 9.53 65 360642 4047 79379634
Human ehrlichiosis 34.89 9.53 25 360682 532 79383149
Dyskinesia 34.87 9.53 96 360611 44677 79339004
Aplastic anaemia 34.85 9.53 167 360540 17738 79365943
Right ventricular failure 34.69 9.53 33 360674 23464 79360217
Depression 34.66 9.53 732 359975 216058 79167623
Pneumocephalus 34.65 9.53 21 360686 333 79383348
Urobilinogen urine increased 34.62 9.53 27 360680 656 79383025
Dyspnoea exertional 34.51 9.53 241 360466 86832 79296849
Necrotising herpetic retinopathy 34.51 9.53 15 360692 112 79383569
Urticaria 34.49 9.53 1089 359618 184112 79199569
Fusarium infection 34.46 9.53 42 360665 1790 79381891
Unevaluable event 34.39 9.53 132 360575 55453 79328228
Infective pulmonary exacerbation of cystic fibrosis 34.27 9.53 8 360699 12843 79370838
Complications of transplant surgery 34.26 9.53 28 360679 729 79382952
Human polyomavirus infection 34.26 9.53 33 360674 1073 79382608
Dermatomyositis 34.26 9.53 60 360647 3563 79380118
Throat tightness 34.24 9.53 230 360477 27677 79356004
Polychondritis 33.98 9.53 25 360682 555 79383126
Escherichia sepsis 33.98 9.53 100 360607 8408 79375273
Gait disturbance 33.96 9.53 698 360009 206808 79176873
Obliterative bronchiolitis 33.78 9.53 54 360653 2974 79380707
CSF oligoclonal band present 33.74 9.53 22 360685 399 79383282
Gastroenteritis rotavirus 33.74 9.53 22 360685 399 79383282
Coronavirus infection 33.74 9.53 92 360615 7405 79376276
Hepatitis 33.63 9.53 393 360314 55334 79328347
Lung transplant rejection 33.62 9.53 38 360669 1493 79382188
Mycotic endophthalmitis 33.61 9.53 17 360690 185 79383496
Oesophageal carcinoma 33.61 9.53 5 360702 11079 79372602
Lung neoplasm malignant 33.47 9.53 46 360661 27746 79355935
Optic neuritis 33.46 9.53 107 360600 9413 79374268
Hypoalbuminaemia 33.38 9.53 187 360520 21110 79362571
Cerebral venous thrombosis 33.36 9.53 51 360656 2702 79380979
Band neutrophil percentage increased 33.36 9.53 22 360685 407 79383274
Adenoviral hepatitis 33.23 9.53 30 360677 897 79382784
Norovirus test positive 33.19 9.53 26 360681 636 79383045
Peritonitis 33.17 9.53 229 360478 27807 79355874
Palmar-plantar erythrodysaesthesia syndrome 33.16 9.53 62 360645 33072 79350609
Chills 33.01 9.53 954 359753 159280 79224401
Abdominal infection 32.90 9.53 59 360648 3570 79380111
Renal graft infection 32.89 9.53 24 360683 526 79383155
Urinary retention 32.82 9.53 138 360569 56492 79327189
Pneumoperitoneum 32.73 9.53 54 360653 3054 79380627
Device leakage 32.69 9.53 5 360702 10851 79372830
Wheezing 32.42 9.53 354 360353 116310 79267371
Immunosuppression 32.23 9.53 129 360578 12674 79371007
Kaposi's sarcoma 32.12 9.53 27 360680 732 79382949
Graft loss 32.08 9.53 31 360676 1012 79382669
American trypanosomiasis 32.00 9.53 20 360687 336 79383345
Thymus hypoplasia 31.98 9.53 30 360677 943 79382738
Oedema 31.98 9.53 366 360341 119214 79264467
Cells in urine 31.96 9.53 17 360690 207 79383474
Transplant dysfunction 31.88 9.53 88 360619 7133 79376548
Renal impairment 31.84 9.53 937 359770 156846 79226835
Cardiac arrest 31.80 9.53 567 360140 171529 79212152
Pregnancy 31.78 9.53 45 360662 26806 79356875
Oliguria 31.66 9.53 152 360555 16157 79367524
Disseminated varicella zoster vaccine virus infection 31.60 9.53 14 360693 110 79383571
Intestinal ischaemia 31.27 9.53 131 360576 13139 79370542
Device dislocation 31.26 9.53 43 360664 25927 79357754
Hypocalcaemia 31.25 9.53 118 360589 49806 79333875
Pneumonia klebsiella 31.20 9.53 70 360637 4984 79378697
Metastases to liver 31.05 9.53 50 360657 28264 79355417
Engraftment syndrome 30.99 9.53 35 360672 1374 79382307
Haemoglobin urine 30.93 9.53 15 360692 148 79383533
Breast cancer female 30.83 9.53 7 360700 11454 79372227
Urine leukocyte esterase 30.79 9.53 16 360691 185 79383496
Abnormal dreams 30.64 9.53 7 360700 11405 79372276
Hospice care 30.53 9.53 5 360702 10319 79373362
Adrenal insufficiency 30.41 9.53 227 360480 28260 79355421
Aphthous ulcer 30.36 9.53 154 360553 16735 79366946
Akathisia 30.32 9.53 11 360696 13248 79370433
Red blood cell count increased 30.25 9.53 62 360645 4146 79379535
Joint swelling 30.09 9.53 1036 359671 287610 79096071
Blood beta-D-glucan increased 29.95 9.53 23 360684 546 79383135
Disorientation 29.95 9.53 164 360543 62612 79321069
Osteoarthritis 29.74 9.53 252 360455 87057 79296624
Cryptococcal meningoencephalitis 29.58 9.53 17 360690 243 79383438
Mean cell haemoglobin increased 29.48 9.53 62 360645 4223 79379458
Coronary artery dilatation 29.37 9.53 10 360697 34 79383647
Malacoplakia gastrointestinal 29.28 9.53 15 360692 168 79383513
Lymphoid tissue hypoplasia 29.28 9.53 28 360679 902 79382779
IgA nephropathy 29.22 9.53 38 360669 1730 79381951
Head injury 29.20 9.53 80 360627 37289 79346392
Laryngeal stenosis 29.15 9.53 30 360677 1058 79382623
Hip arthroplasty 29.11 9.53 75 360632 35681 79348000
Neuralgia 29.11 9.53 254 360453 33130 79350551
Blood immunoglobulin G decreased 29.10 9.53 54 360653 3355 79380326
Serratia infection 29.09 9.53 38 360669 1738 79381943
Erectile dysfunction 29.03 9.53 15 360692 14649 79369032
Heart transplant rejection 29.02 9.53 35 360672 1475 79382206
Eosinophil percentage increased 28.87 9.53 35 360672 1483 79382198
Limbic encephalitis 28.80 9.53 27 360680 848 79382833
Injection site urticaria 28.73 9.53 11 360696 12815 79370866
Hepatic cirrhosis 28.59 9.53 73 360634 34833 79348848
Herpes simplex oesophagitis 28.51 9.53 19 360688 358 79383323
Hepatic artery thrombosis 28.46 9.53 18 360689 309 79383372
Bronchopleural fistula 28.42 9.53 24 360683 655 79383026
Neuromyelitis optica spectrum disorder 28.41 9.53 29 360678 1013 79382668
Granulocyte count increased 28.40 9.53 32 360675 1253 79382428
Enteritis 28.37 9.53 136 360571 14447 79369234
Blood potassium increased 28.23 9.53 56 360651 29219 79354462
Granuloma skin 28.14 9.53 4 360703 9170 79374511
Viral infection 28.05 9.53 308 360399 42708 79340973
Withdrawal syndrome 27.99 9.53 49 360658 26805 79356876
Parvovirus infection 27.99 9.53 24 360683 669 79383012
Smear cervix abnormal 27.98 9.53 45 360662 2491 79381190
Cerebral fungal infection 27.86 9.53 20 360687 427 79383254
Pseudomonal bacteraemia 27.80 9.53 50 360657 3032 79380649
Mean cell haemoglobin concentration decreased 27.80 9.53 63 360644 4516 79379165
Hepatic infarction 27.78 9.53 27 360680 888 79382793
Bacillus infection 27.66 9.53 30 360677 1125 79382556
Urinary tract candidiasis 27.56 9.53 25 360682 752 79382929
Atrioventricular block first degree 27.50 9.53 11 360696 12480 79371201
Therapy partial responder 27.43 9.53 153 360554 17244 79366437
Condition aggravated 27.41 9.53 2627 358080 498497 78885184
Breast cancer 27.39 9.53 71 360636 33710 79349971
Feeding intolerance 27.28 9.53 26 360681 834 79382847
Osteoporosis 27.26 9.53 369 360338 53743 79329938
Type I hypersensitivity 27.25 9.53 61 360646 4337 79379344
Blood parathyroid hormone decreased 27.23 9.53 7 360700 10529 79373152
Natural killer-cell leukaemia 27.23 9.53 12 360695 93 79383588
Dystonia 27.23 9.53 34 360673 21365 79362316
Thrombosis 27.20 9.53 246 360461 83854 79299827
Calcium ionised decreased 27.18 9.53 22 360685 565 79383116
Tendonitis 27.17 9.53 41 360666 23789 79359892
Chronic obstructive pulmonary disease 27.13 9.53 251 360456 85168 79298513
Product dispensing error 27.12 9.53 13 360694 13250 79370431
Subdural haematoma 27.11 9.53 64 360643 31370 79352311
Therapeutic response decreased 27.07 9.53 439 360268 66414 79317267
Inappropriate schedule of product administration 27.05 9.53 433 360274 133195 79250486
Epistaxis 26.90 9.53 349 360358 111166 79272515
Immune reconstitution inflammatory syndrome 26.87 9.53 129 360578 13712 79369969
Listeria encephalitis 26.87 9.53 17 360690 292 79383389
Angiosarcoma 26.58 9.53 20 360687 460 79383221
Monocyte count decreased 26.45 9.53 50 360657 3151 79380530
Aspergillosis oral 26.34 9.53 10 360697 50 79383631
Arteriosclerosis coronary artery 26.33 9.53 25 360682 17791 79365890
Mycobacterial infection 26.32 9.53 54 360653 3614 79380067
Antineutrophil cytoplasmic antibody positive 26.30 9.53 31 360676 1275 79382406
Epstein-Barr virus test positive 26.26 9.53 29 360678 1110 79382571
Amnesia 26.25 9.53 172 360535 62885 79320796
Pyelonephritis 26.20 9.53 170 360537 20218 79363463
Magnetic resonance imaging abnormal 26.10 9.53 52 360655 3407 79380274
Body temperature fluctuation 26.09 9.53 55 360652 3752 79379929
Band neutrophil count increased 26.06 9.53 23 360684 667 79383014
Transfusion 26.00 9.53 35 360672 21295 79362386
Product complaint 25.92 9.53 14 360693 13335 79370346
Alveolitis 25.92 9.53 58 360649 4122 79379559
Intestine transplant rejection 25.91 9.53 11 360696 77 79383604
Urinary tract infection bacterial 25.90 9.53 76 360631 6380 79377301
Pulmonary arterial hypertension 25.89 9.53 56 360651 28310 79355371
Weight increased 25.78 9.53 1517 359190 275869 79107812
Product administration error 25.77 9.53 67 360640 31779 79351902
Perforation 25.70 9.53 32 360675 1394 79382287
Hepatic function abnormal 25.60 9.53 469 360238 72638 79311043
Dry skin 25.59 9.53 191 360516 67804 79315877
Reticulocytosis 25.54 9.53 20 360687 489 79383192
Pyelonephritis fungal 25.53 9.53 15 360692 224 79383457
Meningoencephalitis viral 25.51 9.53 19 360688 430 79383251
Lower limb fracture 25.46 9.53 41 360666 23174 79360507
Serum ferritin increased 25.42 9.53 100 360607 9747 79373934
pH urine increased 25.40 9.53 19 360688 433 79383248
Proteus infection 25.33 9.53 39 360668 2079 79381602
Bifidobacterium infection 25.31 9.53 9 360698 36 79383645
Venoocclusive liver disease 25.28 9.53 113 360594 11658 79372023
Neutropenic sepsis 25.06 9.53 53 360654 27011 79356670
Adenoviral haemorrhagic cystitis 24.99 9.53 20 360687 505 79383176
Monocytopenia 24.97 9.53 13 360694 151 79383530
Enterovirus infection 24.92 9.53 37 360670 1910 79381771
Shock 24.91 9.53 304 360403 43244 79340437
Parkinsonism 24.83 9.53 23 360684 16561 79367120
Flatulence 24.83 9.53 104 360603 42620 79341061
Dementia 24.80 9.53 46 360661 24613 79359068
Salivary hypersecretion 24.72 9.53 17 360690 14207 79369474
Pneumatosis 24.70 9.53 25 360682 864 79382817
Hypokalaemia 24.61 9.53 481 360226 143559 79240122
Temperature intolerance 24.61 9.53 98 360609 9607 79374074
Bacterial vulvovaginitis 24.53 9.53 21 360686 584 79383097
Myelitis 24.45 9.53 41 360666 2350 79381331
Leukocyturia 24.40 9.53 37 360670 1946 79381735
Herpes simplex hepatitis 24.34 9.53 20 360687 525 79383156
Drug level decreased 24.28 9.53 129 360578 14273 79369408
Leukocytosis 24.27 9.53 302 360405 43153 79340528
Angiocentric lymphoma 24.24 9.53 25 360682 884 79382797
Anaphylactic reaction 24.22 9.53 522 360185 83221 79300460
Lip pruritus 24.17 9.53 25 360682 887 79382794
Rash 24.14 9.53 2270 358437 576088 78807593
Neoplasm progression 24.12 9.53 136 360571 51546 79332135
Myoclonus 24.10 9.53 56 360651 27604 79356077
Renal tubular injury 24.10 9.53 32 360675 1487 79382194
Periumbilical abscess 24.05 9.53 10 360697 66 79383615
Cerebral artery stenosis 24.03 9.53 23 360684 742 79382939
Arteriovenous fistula 23.79 9.53 30 360677 1324 79382357
Blood loss anaemia 23.79 9.53 21 360686 15477 79368204
Nodular regenerative hyperplasia 23.67 9.53 30 360677 1331 79382350
Pancreas transplant rejection 23.67 9.53 16 360691 309 79383372
Hepatic cancer 23.63 9.53 9 360698 10520 79373161
Sensitivity to weather change 23.57 9.53 4 360703 8043 79375638
Adjustment disorder with depressed mood 23.56 9.53 6 360701 9080 79374601
Miosis 23.52 9.53 22 360685 15767 79367914
Lip swelling 23.52 9.53 100 360607 40811 79342870
Peripheral vascular disorder 23.50 9.53 4 360703 8026 79375655
Hepatitis B 23.47 9.53 87 360620 8245 79375436
Encephalopathy 23.47 9.53 432 360275 66965 79316716
Drug level below therapeutic 23.45 9.53 97 360610 9673 79374008
Oral pain 23.43 9.53 70 360637 31728 79351953
Vaccination failure 23.41 9.53 35 360672 1818 79381863
Mental status changes 23.37 9.53 192 360515 66767 79316914
Creatinine renal clearance decreased 23.34 9.53 31 360676 18971 79364710
Sense of oppression 23.34 9.53 32 360675 1534 79382147
Atypical haemolytic uraemic syndrome 23.32 9.53 26 360681 1006 79382675
Drug tolerance decreased 23.24 9.53 15 360692 12963 79370718
Bronchospasm 23.18 9.53 192 360515 24667 79359014
Electrocardiogram QRS complex prolonged 23.11 9.53 10 360697 10823 79372858
Staphylococcal mediastinitis 23.08 9.53 9 360698 49 79383632
Central nervous system lymphoma 23.08 9.53 39 360668 2250 79381431
Encephalitis autoimmune 23.02 9.53 39 360668 2255 79381426
Blood glucose decreased 22.95 9.53 53 360654 26181 79357500
Non-consummation 22.93 9.53 9 360698 50 79383631
Anorectal ulcer 22.93 9.53 9 360698 50 79383631
Abscess 22.89 9.53 180 360527 22771 79360910
Poikiloderma 22.78 9.53 17 360690 386 79383295
Cytomegalovirus gastritis 22.75 9.53 18 360689 447 79383234
Immune effector cell-associated neurotoxicity syndrome 22.66 9.53 68 360639 5780 79377901
Biloma 22.64 9.53 12 360695 145 79383536
CSF protein increased 22.63 9.53 28 360679 1212 79382469
Presyncope 22.60 9.53 102 360605 40952 79342729
Mean cell haemoglobin concentration increased 22.59 9.53 24 360683 879 79382802
Urine bilirubin decreased 22.57 9.53 12 360695 146 79383535
Road traffic accident 22.55 9.53 111 360596 43553 79340128
Graft complication 22.55 9.53 22 360685 727 79382954
Blindness cortical 22.53 9.53 25 360682 962 79382719
Angina unstable 22.38 9.53 25 360682 16502 79367179
Factor XIII deficiency 22.31 9.53 10 360697 81 79383600
Night sweats 22.24 9.53 141 360566 51954 79331727
Meningitis cryptococcal 22.14 9.53 49 360658 3457 79380224
Atypical mycobacterial infection 22.13 9.53 33 360674 1710 79381971
Pulmonary tuberculosis 22.05 9.53 82 360625 7783 79375898
Scopulariopsis infection 22.05 9.53 11 360696 116 79383565
Organising pneumonia 22.00 9.53 103 360604 10836 79372845
B-cell lymphoma 21.98 9.53 70 360637 6145 79377536
Parainfluenzae virus infection 21.95 9.53 66 360641 5616 79378065
Immunoglobulins decreased 21.94 9.53 31 360676 1529 79382152
Mean cell haemoglobin decreased 21.91 9.53 70 360637 6154 79377527
Blood sodium decreased 21.87 9.53 77 360630 33178 79350503
Eosinophil percentage decreased 21.87 9.53 15 360692 297 79383384
Intracranial infection 21.80 9.53 10 360697 86 79383595
Breast cancer stage II 21.76 9.53 5 360702 8115 79375566
Atypical mycobacterial pneumonia 21.74 9.53 12 360695 158 79383523
Interstitial lung disease 21.72 9.53 665 360042 111935 79271746
Staphylococcal bacteraemia 21.68 9.53 111 360596 12107 79371574
Toxic epidermal necrolysis 21.64 9.53 302 360405 44279 79339402
Disseminated aspergillosis 21.63 9.53 26 360681 1092 79382589
Body temperature increased 21.60 9.53 301 360406 44119 79339562
Lymphocele 21.59 9.53 32 360675 1649 79382032
Rubella antibody positive 21.57 9.53 9 360698 60 79383621
Tri-iodothyronine free increased 21.56 9.53 14 360693 252 79383429
Renal vein thrombosis 21.50 9.53 19 360688 552 79383129
Morganella infection 21.46 9.53 26 360681 1101 79382580
Blood albumin increased 21.46 9.53 30 360677 1465 79382216
Viral cardiomyopathy 21.40 9.53 8 360699 38 79383643
Colitis ulcerative 21.40 9.53 246 360461 34496 79349185
Fungal skin infection 21.36 9.53 68 360639 5968 79377713
Viral sepsis 21.35 9.53 12 360695 164 79383517
Autoimmune thyroiditis 21.14 9.53 54 360653 4179 79379502
Eye pruritus 21.02 9.53 38 360669 20532 79363149
Cestode infection 21.00 9.53 14 360693 264 79383417
Joint injury 20.98 9.53 72 360635 31263 79352418
Tuberculosis 20.94 9.53 129 360578 15069 79368612
Prescribed overdose 20.92 9.53 94 360613 37789 79345892
Intestinal ulcer 20.91 9.53 35 360672 2003 79381678
Menstruation irregular 20.89 9.53 60 360647 4976 79378705
Lipaemic index score 20.89 9.53 11 360696 131 79383550
Agitation 20.89 9.53 321 360386 99394 79284287
Cataract 20.88 9.53 396 360311 61724 79321957
Sideroblastic anaemia 20.86 9.53 14 360693 267 79383414
Leukoencephalopathy 20.86 9.53 81 360626 7848 79375833
Cholelithiasis 20.75 9.53 146 360561 52518 79331163
Capillaritis 20.59 9.53 14 360693 273 79383408
Thunderclap headache 20.51 9.53 16 360691 389 79383292
Nocturia 20.45 9.53 19 360688 13662 79370019
Atrioventricular block 20.40 9.53 20 360687 14021 79369660
Orbital apex syndrome 20.39 9.53 9 360698 70 79383611
Oropharyngeal pain 20.34 9.53 643 360064 108710 79274971
Multiple allergies 20.27 9.53 11 360696 10449 79373232
Musculoskeletal pain 20.27 9.53 333 360374 102021 79281660
White blood cell count increased 20.24 9.53 461 360246 74172 79309509
Microscopic polyangiitis 20.23 9.53 16 360691 397 79383284
Finger deformity 20.19 9.53 77 360630 7397 79376284
Blood brain barrier defect 20.19 9.53 11 360696 141 79383540
Coma scale abnormal 20.19 9.53 7 360700 8671 79375010
Autoimmune hepatitis 20.18 9.53 106 360601 11677 79372004
Melaena 20.17 9.53 177 360530 60713 79322968
Kidney rupture 20.12 9.53 13 360694 232 79383449
Escherichia urinary tract infection 20.10 9.53 119 360588 13706 79369975
Malacoplakia vesicae 20.07 9.53 9 360698 73 79383608
Eye infection toxoplasmal 20.05 9.53 18 360689 534 79383147
Meningitis fungal 20.04 9.53 12 360695 186 79383495
Respiratory tract infection fungal 19.94 9.53 26 360681 1187 79382494
Urine oxalate increased 19.93 9.53 13 360694 236 79383445
Visceral leishmaniasis 19.92 9.53 25 360682 1098 79382583
Aplasia pure red cell 19.91 9.53 79 360628 7731 79375950
Chronic kidney disease 19.90 9.53 197 360510 65957 79317724
JC polyomavirus test positive 19.87 9.53 30 360677 1572 79382109
Diabetic ketoacidosis 19.86 9.53 83 360624 34039 79349642
Coccidioidomycosis 19.84 9.53 27 360680 1285 79382396
Blood creatinine decreased 19.83 9.53 79 360628 7746 79375935
Paraesthesia ear 19.82 9.53 14 360693 291 79383390
Depressed mood 19.79 9.53 133 360574 48347 79335334
Malacoplakia 19.75 9.53 19 360688 617 79383064
Eschar 19.75 9.53 27 360680 1291 79382390
Engraft failure 19.72 9.53 20 360687 693 79382988
Deep vein thrombosis 19.69 9.53 407 360300 120512 79263169
Blood lactate dehydrogenase increased 19.69 9.53 267 360440 38903 79344778
Premenstrual syndrome 19.67 9.53 18 360689 548 79383133
Pyelonephritis acute 19.65 9.53 66 360641 5957 79377724
Klebsiella test positive 19.60 9.53 31 360676 1692 79381989
Thyrotoxic periodic paralysis 19.59 9.53 11 360696 150 79383531
Microsporidia infection 19.57 9.53 23 360684 943 79382738
Mitochondrial DNA mutation 19.57 9.53 16 360691 417 79383264
Ageusia 19.56 9.53 28 360679 16604 79367077
Hot flush 19.54 9.53 353 360354 54524 79329157
Anti-thyroid antibody positive 19.52 9.53 17 360690 484 79383197
Passenger lymphocyte syndrome 19.52 9.53 10 360697 112 79383569
Injection site induration 19.51 9.53 10 360697 9809 79373872
Acute disseminated encephalomyelitis 19.50 9.53 14 360693 299 79383382
Tremor 19.48 9.53 603 360104 169480 79214201
Meningomyelitis herpes 19.46 9.53 9 360698 79 79383602
Bradyphrenia 19.46 9.53 12 360695 10628 79373053
Human herpesvirus 6 infection reactivation 19.42 9.53 18 360689 557 79383124
Cutaneous malacoplakia 19.37 9.53 10 360697 114 79383567
Sinusitis 19.37 9.53 706 360001 194795 79188886
Meningitis bacterial 19.34 9.53 40 360667 2692 79380989
Joint tuberculosis 19.34 9.53 11 360696 154 79383527
Amoebiasis 19.29 9.53 10 360697 115 79383566
Splenic embolism 19.28 9.53 12 360695 200 79383481
Gastrointestinal mucormycosis 19.28 9.53 16 360691 426 79383255
Cutaneous nocardiosis 19.18 9.53 12 360695 202 79383479
White blood cells urine 19.18 9.53 17 360690 496 79383185
Post-traumatic stress disorder 19.14 9.53 57 360650 4824 79378857
Intestinal obstruction 19.11 9.53 115 360592 42905 79340776
Fracture 19.11 9.53 44 360663 21757 79361924
Red blood cell schistocytes present 19.05 9.53 18 360689 571 79383110
Lichen sclerosus 19.04 9.53 23 360684 971 79382710
Jaundice cholestatic 18.93 9.53 14 360693 11270 79372411
Suspected COVID-19 18.90 9.53 43 360664 3090 79380591
Terminal ileitis 18.85 9.53 22 360685 895 79382786
Pulmonary embolism 18.83 9.53 612 360095 171042 79212639
Cytomegalovirus duodenitis 18.81 9.53 9 360698 86 79383595
Post cholecystectomy syndrome 18.80 9.53 15 360692 377 79383304
Haemorrhoids 18.78 9.53 68 360639 29060 79354621
Uterine perforation 18.76 9.53 3 360704 6300 79377381
Lymphoproliferative disorder 18.73 9.53 62 360645 5553 79378128
Hypofibrinogenaemia 18.73 9.53 33 360674 1969 79381712
CSF measles antibody positive 18.72 9.53 8 360699 57 79383624
Pancytopenia 18.68 9.53 923 359784 164822 79218859
Rhesus antigen positive 18.64 9.53 10 360697 124 79383557
Herpes zoster meningoencephalitis 18.64 9.53 20 360687 741 79382940
Ultrasound ovary abnormal 18.63 9.53 9 360698 88 79383593
Muscle twitching 18.62 9.53 54 360653 24710 79358971
Pharyngeal dyskinesia 18.61 9.53 8 360699 58 79383623
Dysmenorrhoea 18.60 9.53 42 360665 3003 79380678
Haemorrhagic varicella syndrome 18.57 9.53 5 360702 5 79383676
Antinuclear antibody 18.51 9.53 16 360691 451 79383230
Thrombocytopenic purpura 18.49 9.53 37 360670 2432 79381249
Hypoacusis 18.39 9.53 72 360635 30078 79353603
Double stranded DNA antibody positive 18.39 9.53 16 360691 455 79383226
Thymoma 18.37 9.53 13 360694 271 79383410
Wound evisceration 18.36 9.53 10 360697 128 79383553
Biliary anastomosis complication 18.28 9.53 11 360696 172 79383509
Irritability 18.27 9.53 110 360597 41034 79342647
Haemoperitoneum 18.27 9.53 52 360655 4291 79379390
Breast cancer stage I 18.21 9.53 4 360703 6696 79376985
Peritoneal candidiasis 18.18 9.53 6 360701 18 79383663
Vitritis infective 18.18 9.53 6 360701 18 79383663
Sputum discoloured 18.17 9.53 45 360662 21698 79361983
Schizophrenia 18.15 9.53 26 360681 15414 79368267
Exophthalmos 18.14 9.53 30 360677 1700 79381981
Torulopsis infection 18.12 9.53 7 360700 37 79383644
Cytokine storm 18.10 9.53 23 360684 1023 79382658
Anti-cyclic citrullinated peptide antibody 18.10 9.53 63 360644 5789 79377892
Vesicoureteric reflux 18.10 9.53 10 360697 132 79383549
Breast cancer stage III 18.09 9.53 11 360696 9815 79373866
Aspergilloma 18.08 9.53 18 360689 610 79383071
Delayed engraftment 18.05 9.53 13 360694 279 79383402
Steroid dependence 18.03 9.53 38 360669 2592 79381089
Hypomagnesaemia 18.02 9.53 131 360576 46780 79336901
Injection site extravasation 17.97 9.53 89 360618 9580 79374101
Graft infection 17.97 9.53 19 360688 692 79382989
Perineal ulceration 17.94 9.53 8 360699 64 79383617
Atrial flutter 17.88 9.53 45 360662 21580 79362101
Femur fracture 17.88 9.53 102 360605 38550 79345131
Blood pressure systolic decreased 17.86 9.53 98 360609 10978 79372703
Quadriparesis 17.83 9.53 45 360662 3456 79380225
Metastases to bone 17.83 9.53 54 360653 24373 79359308
Birdshot chorioretinopathy 17.83 9.53 8 360699 65 79383616
Haemolysis 17.81 9.53 109 360598 12703 79370978
Multiple fractures 17.78 9.53 7 360700 8019 79375662
Tumour lysis syndrome 17.78 9.53 176 360531 23763 79359918
Tumefactive multiple sclerosis 17.71 9.53 9 360698 99 79383582
Dengue fever 17.70 9.53 21 360686 870 79382811
Reticulocytopenia 17.69 9.53 12 360695 233 79383448
Bacterial pyelonephritis 17.67 9.53 17 360690 552 79383129
Angiosarcoma metastatic 17.65 9.53 10 360697 139 79383542
Hypertensive encephalopathy 17.64 9.53 22 360685 960 79382721
Thirst 17.63 9.53 36 360671 18583 79365098
Blood immunoglobulin A increased 17.62 9.53 22 360685 961 79382720
Cystitis viral 17.59 9.53 19 360688 709 79382972
Hypoproteinaemia 17.56 9.53 49 360658 3997 79379684
Tuberculosis gastrointestinal 17.54 9.53 17 360690 557 79383124
Neuropsychiatric lupus 17.54 9.53 11 360696 186 79383495
Muscle rigidity 17.53 9.53 40 360667 19842 79363839
B-lymphocyte count increased 17.52 9.53 10 360697 141 79383540
Hepatic failure 17.52 9.53 381 360326 60831 79322850
Capillary leak syndrome 17.50 9.53 48 360659 3877 79379804
Central nervous system lupus 17.48 9.53 16 360691 487 79383194
Post procedural bile leak 17.47 9.53 15 360692 419 79383262
Monocyte percentage decreased 17.47 9.53 13 360694 294 79383387
Aspartate aminotransferase 17.32 9.53 17 360690 566 79383115
Myelocyte percentage increased 17.30 9.53 12 360695 242 79383439
Colitis microscopic 17.25 9.53 14 360693 10754 79372927
Bordetella infection 17.25 9.53 9 360698 105 79383576
Bundle branch block left 17.20 9.53 16 360691 11497 79372184
Gastroduodenal ulcer 17.19 9.53 16 360691 498 79383183
Neurosarcoidosis 17.15 9.53 14 360693 364 79383317
Retinal detachment 17.10 9.53 85 360622 9162 79374519
Tri-iodothyronine free decreased 17.08 9.53 14 360693 366 79383315
Electrocardiogram abnormal 17.03 9.53 31 360676 16706 79366975
Rash maculo-papular 17.00 9.53 352 360355 55726 79327955
Liver function test abnormal 16.98 9.53 198 360509 64277 79319404
Renal artery stenosis 16.95 9.53 44 360663 3438 79380243
Human herpesvirus 6 encephalitis 16.92 9.53 18 360689 660 79383021
Creatinine urine decreased 16.88 9.53 12 360695 252 79383429
Angioedema 16.88 9.53 242 360465 75793 79307888
Hyperoxaluria 16.88 9.53 13 360694 310 79383371
Growth retardation 16.87 9.53 31 360676 1912 79381769
Abdominal distension 16.85 9.53 412 360295 119238 79264443
Immunoglobulin G4 related disease 16.80 9.53 12 360695 254 79383427
Klebsiella sepsis 16.78 9.53 42 360665 3210 79380471
Papilloma viral infection 16.77 9.53 29 360678 1705 79381976
Cerebral venous sinus thrombosis 16.76 9.53 34 360673 2257 79381424
Nephrolithiasis 16.75 9.53 157 360550 53134 79330547
Hepatocellular carcinoma 16.74 9.53 10 360697 9011 79374670
Cytopenia 16.70 9.53 153 360554 20230 79363451
Hiatus hernia 16.69 9.53 52 360655 23260 79360421
Thrombotic thrombocytopenic purpura 16.66 9.53 65 360642 6311 79377370
Syringe issue 16.64 9.53 4 360703 6294 79377387
Aspiration 16.63 9.53 42 360665 20116 79363565
Porphyria acute 16.61 9.53 27 360680 1508 79382173
Aspergillus test positive 16.56 9.53 19 360688 759 79382922
Migraine 16.56 9.53 287 360420 87206 79296475
Gynaecomastia 16.53 9.53 7 360700 7674 79376007
Acute respiratory failure 16.53 9.53 369 360338 59172 79324509
Brain oedema 16.52 9.53 181 360526 25082 79358599
Q fever 16.52 9.53 12 360695 261 79383420
Glucose urine present 16.50 9.53 29 360678 1727 79381954
Muir-Torre syndrome 16.49 9.53 7 360700 49 79383632
Tachycardia 16.46 9.53 972 359735 176796 79206885
Catheterisation cardiac 16.44 9.53 3 360704 5725 79377956
Central obesity 16.44 9.53 29 360678 1732 79381949
IVth nerve paralysis 16.42 9.53 10 360697 160 79383521
Paranoia 16.41 9.53 40 360667 19392 79364289
Injection site discolouration 16.29 9.53 7 360700 7607 79376074
Trichodysplasia spinulosa 16.28 9.53 19 360688 773 79382908
Sudden death 16.27 9.53 50 360657 22461 79361220
Eye luxation 16.25 9.53 5 360702 11 79383670
Faecaloma 16.20 9.53 17 360690 11547 79372134
Diarrhoea haemorrhagic 16.19 9.53 109 360598 13125 79370556
Herpes simplex reactivation 16.19 9.53 15 360692 464 79383217
Erosive duodenitis 16.18 9.53 32 360675 2085 79381596
Renal necrosis 16.17 9.53 12 360695 270 79383411
Paraplegia 16.15 9.53 55 360652 4998 79378683
Blastomycosis 16.05 9.53 18 360689 701 79382980
Subcutaneous emphysema 16.05 9.53 29 360678 1765 79381916
Hepatic artery occlusion 15.98 9.53 8 360699 85 79383596
Emphysematous pyelonephritis 15.92 9.53 13 360694 338 79383343
Oral fungal infection 15.92 9.53 45 360662 3698 79379983
Complications of transplanted liver 15.92 9.53 14 360693 404 79383277
Encephalomyelitis 15.85 9.53 11 360696 222 79383459
Prescribed underdose 15.84 9.53 74 360633 29440 79354241
Bronchial anastomosis complication 15.80 9.53 7 360700 55 79383626
Red blood cell sedimentation rate 15.79 9.53 3 360704 5562 79378119
Drug eruption 15.78 9.53 125 360582 43810 79339871
Demodicidosis 15.77 9.53 11 360696 224 79383457
Diaphragmatic injury 15.76 9.53 9 360698 127 79383554
Dehiscence 15.74 9.53 10 360697 173 79383508
Fungal test positive 15.74 9.53 22 360685 1074 79382607
Herpes simplex encephalitis 15.71 9.53 18 360689 718 79382963
Adrenal atrophy 15.69 9.53 7 360700 56 79383625
Diastolic hypotension 15.69 9.53 10 360697 174 79383507
Seizure 15.67 9.53 696 360011 188138 79195543
Gastroenteritis Escherichia coli 15.66 9.53 17 360690 638 79383043
Fungal sepsis 15.64 9.53 29 360678 1801 79381880
Abscess fungal 15.63 9.53 13 360694 347 79383334
Intravascular haemolysis 15.56 9.53 19 360688 811 79382870
Brain herniation 15.55 9.53 71 360636 7392 79376289
Pericarditis fungal 15.50 9.53 10 360697 178 79383503
Gastrointestinal candidiasis 15.47 9.53 14 360693 420 79383261
Disability 15.46 9.53 34 360673 17086 79366595
Cholecystectomy 15.44 9.53 12 360695 9420 79374261
Chronic graft versus host disease in liver 15.41 9.53 17 360690 650 79383031
Wolff-Parkinson-White syndrome 15.41 9.53 12 360695 291 79383390
Vaginal haemorrhage 15.38 9.53 49 360658 21768 79361913
Panniculitis 15.38 9.53 20 360687 12351 79371330
Encephalitis fungal 15.35 9.53 10 360697 181 79383500
Peliosis hepatis 15.34 9.53 9 360698 134 79383547
Oral candidiasis 15.32 9.53 203 360504 29425 79354256
Oral bacterial infection 15.28 9.53 7 360700 60 79383621
Oral discomfort 15.26 9.53 13 360694 9747 79373934
Body height decreased 15.25 9.53 10 360697 8570 79375111
Pneumonia necrotising 15.25 9.53 23 360684 1204 79382477
SARS-CoV-2 test positive 15.25 9.53 98 360609 11618 79372063
Bone marrow failure 15.23 9.53 320 360387 50787 79332894
Colitis 15.23 9.53 437 360270 72870 79310811
Hairy cell leukaemia 15.21 9.53 8 360699 95 79383586
Asthma 15.21 9.53 480 360227 134615 79249066
Glomerulonephritis rapidly progressive 15.21 9.53 27 360680 1621 79382060
Beta 2 microglobulin increased 15.20 9.53 13 360694 361 79383320
Respiratory gas exchange disorder 15.18 9.53 19 360688 832 79382849
Skin cancer 15.18 9.53 28 360679 15012 79368669
Mucosal ulceration 15.16 9.53 29 360678 1844 79381837
Swollen joint count increased 15.13 9.53 53 360654 22874 79360807
Chorioretinitis 15.12 9.53 21 360686 1019 79382662
Encephalitis brain stem 15.12 9.53 11 360696 240 79383441
Dry throat 15.09 9.53 72 360635 7634 79376047
Gastropleural fistula 15.08 9.53 7 360700 62 79383619
Sodium retention 15.07 9.53 10 360697 187 79383494
Faeces discoloured 15.07 9.53 74 360633 29053 79354628
Diffuse large B-cell lymphoma stage III 15.07 9.53 8 360699 97 79383584
Sinus node dysfunction 15.07 9.53 8 360699 7693 79375988
Intra-abdominal haemorrhage 15.03 9.53 50 360657 4490 79379191
Herpes simplex viraemia 15.01 9.53 14 360693 437 79383244
Hepatic necrosis 15.00 9.53 81 360626 9019 79374662
Alcohol abuse 14.99 9.53 3 360704 5360 79378321
Enterococcal sepsis 14.90 9.53 36 360671 2690 79380991
Hypercholesterolaemia 14.89 9.53 165 360542 22930 79360751
Meningitis exserohilum 14.86 9.53 4 360703 4 79383677
Escherichia bacteraemia 14.86 9.53 64 360643 6498 79377183
Heliotrope rash 14.84 9.53 10 360697 192 79383489
Disseminated coccidioidomycosis 14.83 9.53 9 360698 143 79383538
Tricuspid valve incompetence 14.81 9.53 43 360664 19669 79364012
Fungal endocarditis 14.80 9.53 16 360691 598 79383083
Diverticulum 14.79 9.53 28 360679 14868 79368813
Complication associated with device 14.79 9.53 36 360671 17460 79366221
Acne 14.77 9.53 188 360519 27002 79356679
Polyglandular disorder 14.77 9.53 6 360701 37 79383644
Impaired work ability 14.74 9.53 43 360664 19638 79364043
Post procedural urine leak 14.73 9.53 9 360698 145 79383536
Sensory loss 14.71 9.53 105 360602 12886 79370795
Ependymoma 14.71 9.53 7 360700 66 79383615
Thyroid stimulating immunoglobulin 14.71 9.53 7 360700 66 79383615
Infusion site extravasation 14.69 9.53 87 360620 10021 79373660
Acinetobacter test positive 14.66 9.53 11 360696 252 79383429
Tinnitus 14.63 9.53 129 360578 44204 79339477
Bronchopneumopathy 14.62 9.53 18 360689 775 79382906
Red cell distribution width decreased 14.62 9.53 30 360677 2008 79381673
Herpes simplex meningoencephalitis 14.62 9.53 7 360700 67 79383614
Leishmaniasis 14.62 9.53 13 360694 381 79383300
International normalised ratio abnormal 14.59 9.53 4 360703 5764 79377917
Hyperthermia 14.58 9.53 135 360572 17902 79365779
Pyomyositis 14.56 9.53 16 360691 609 79383072
Gonococcal infection 14.53 9.53 7 360700 68 79383613
Tularaemia 14.52 9.53 8 360699 105 79383576
Meningitis aseptic 14.50 9.53 66 360641 6862 79376819
Cyanosis 14.49 9.53 176 360531 25006 79358675
Cytomegalovirus nephritis 14.46 9.53 9 360698 150 79383531
CD8 lymphocytes decreased 14.44 9.53 11 360696 258 79383423
Muscle abscess 14.39 9.53 21 360686 1067 79382614
Bladder cancer 14.37 9.53 43 360664 19483 79364198
Hip fracture 14.32 9.53 81 360626 30680 79353001
Delusion 14.31 9.53 46 360661 20377 79363304
Venous thrombosis 14.31 9.53 67 360640 7049 79376632
Hemianopia 14.29 9.53 27 360680 1701 79381980
Nephrogenic systemic fibrosis 14.28 9.53 5 360702 6155 79377526
Wound infection bacterial 14.26 9.53 19 360688 886 79382795
Transient hypogammaglobulinaemia of infancy 14.25 9.53 6 360701 41 79383640
Cerebellar stroke 14.24 9.53 15 360692 544 79383137
Haematopoietic stem cell mobilisation 14.24 9.53 10 360697 206 79383475
Second primary malignancy 14.23 9.53 27 360680 14323 79369358
Mean cell volume decreased 14.23 9.53 52 360655 4895 79378786
Varicella 14.23 9.53 37 360670 2895 79380786
Arterial rupture 14.21 9.53 18 360689 798 79382883
Erythema infectiosum 14.19 9.53 10 360697 207 79383474
Product label confusion 14.19 9.53 26 360681 1600 79382081
Colorectal cancer 14.16 9.53 11 360696 8636 79375045
Shock symptom 14.15 9.53 10 360697 208 79383473
Anti-neutrophil cytoplasmic antibody positive vasculitis 14.11 9.53 43 360664 3686 79379995
Back disorder 14.11 9.53 19 360688 11559 79372122
Superinfection bacterial 14.10 9.53 25 360682 1499 79382182
Rhinitis allergic 14.09 9.53 21 360686 12248 79371433
Lymphocytosis 14.07 9.53 50 360657 4643 79379038
Therapy change 14.02 9.53 8 360699 7391 79376290
Breast cancer metastatic 14.01 9.53 11 360696 8591 79375090
Hepatitis cholestatic 14.01 9.53 109 360598 13743 79369938
Propofol infusion syndrome 14 9.53 29 360678 1954 79381727
Application site erythema 13.99 9.53 3 360704 5107 79378574
Therapeutic response shortened 13.99 9.53 121 360586 15742 79367939
Myelocyte present 13.97 9.53 4 360703 6 79383675
Multi-organ disorder 13.96 9.53 34 360673 2554 79381127
Insomnia 13.96 9.53 938 359769 244232 79139449
Clostridium colitis 13.95 9.53 36 360671 2803 79380878
Pneumonia lipoid 13.91 9.53 9 360698 161 79383520
Lactic acidosis 13.90 9.53 229 360478 70130 79313551
Oxygen saturation abnormal 13.89 9.53 49 360658 4533 79379148
Histoplasmosis disseminated 13.87 9.53 32 360675 2321 79381360
Sexual dysfunction 13.86 9.53 9 360698 7754 79375927
Coronary arterial stent insertion 13.85 9.53 5 360702 6039 79377642
Pre-existing condition improved 13.81 9.53 4 360703 5559 79378122
Blood calcium increased 13.79 9.53 16 360691 10384 79373297
Radiotherapy to brain 13.78 9.53 6 360701 45 79383636
Stridor 13.77 9.53 55 360652 5398 79378283
Hallucination, visual 13.76 9.53 89 360618 32640 79351041
Blood thyroid stimulating hormone increased 13.76 9.53 83 360624 9625 79374056
Arterial occlusive disease 13.75 9.53 75 360632 8381 79375300
Meningitis chemical 13.75 9.53 10 360697 218 79383463
Acute myeloid leukaemia recurrent 13.74 9.53 40 360667 3343 79380338
Hepatic steatosis 13.73 9.53 107 360600 37631 79346050
Bone infarction 13.71 9.53 14 360693 489 79383192
Urinoma 13.71 9.53 10 360697 219 79383462
Clumsiness 13.70 9.53 38 360669 3089 79380592
Familial periodic paralysis 13.67 9.53 9 360698 166 79383515
Blindness 13.66 9.53 192 360515 28191 79355490
Renal haemorrhage 13.65 9.53 31 360676 2225 79381456
Pancreatitis 13.61 9.53 223 360484 68352 79315329
Cardiac operation 13.60 9.53 3 360704 5009 79378672
Paraparesis 13.60 9.53 43 360664 3760 79379921
Scleritis 13.56 9.53 47 360660 4309 79379372
Acute allograft nephropathy 13.56 9.53 6 360701 47 79383634
Femoral nerve palsy 13.54 9.53 7 360700 80 79383601
Asphyxia 13.52 9.53 20 360687 11700 79371981
Disseminated toxoplasmosis 13.52 9.53 10 360697 224 79383457
Fibromyalgia 13.51 9.53 207 360500 64133 79319548
Groin pain 13.51 9.53 24 360683 13056 79370625
Chimerism 13.51 9.53 11 360696 285 79383396
Vessel puncture site bruise 13.51 9.53 14 360693 498 79383183
Aortitis salmonella 13.51 9.53 5 360702 23 79383658
Breast abscess 13.50 9.53 24 360683 1442 79382239
Paralysis 13.50 9.53 104 360603 13073 79370608
Dysstasia 13.50 9.53 72 360635 27674 79356007
Parathyroid hyperplasia 13.49 9.53 9 360698 170 79383511
Carotid artery occlusion 13.47 9.53 9 360698 7638 79376043
Pleural mass 13.47 9.53 7 360700 81 79383600
Ovarian fibroma 13.47 9.53 7 360700 81 79383600
Cryptitis 13.44 9.53 11 360696 287 79383394
Episcleritis 13.43 9.53 20 360687 1035 79382646
Large intestine polyp 13.42 9.53 23 360684 12685 79370996
Obsessive-compulsive disorder 13.41 9.53 5 360702 5922 79377759
Butterfly rash 13.41 9.53 26 360681 1670 79382011
Accelerated idioventricular rhythm 13.40 9.53 10 360697 227 79383454
Listeria sepsis 13.40 9.53 17 360690 755 79382926
Cold type haemolytic anaemia 13.40 9.53 12 360695 355 79383326
Tension headache 13.38 9.53 8 360699 7203 79376478
Hepatitis A 13.37 9.53 19 360688 942 79382739
Necrosis 13.35 9.53 81 360626 9412 79374269
Uraemic encephalopathy 13.33 9.53 16 360691 671 79383010
Complication of device insertion 13.33 9.53 6 360701 6344 79377337
Osteogenesis imperfecta 13.30 9.53 14 360693 507 79383174
Rheumatoid factor increased 13.29 9.53 27 360680 1794 79381887
Meningoencephalitis bacterial 13.29 9.53 10 360697 230 79383451
Abnormal loss of weight 13.28 9.53 11 360696 8365 79375316
Gastrointestinal fungal infection 13.28 9.53 14 360693 508 79383173
Abdominal compartment syndrome 13.26 9.53 25 360682 1572 79382109
Moyamoya disease 13.25 9.53 7 360700 84 79383597
Citrobacter infection 13.24 9.53 19 360688 951 79382730
H3N2 influenza 13.21 9.53 3 360704 0 79383681
Capnocytophaga infection 13.19 9.53 8 360699 127 79383554
Gastroenteritis salmonella 13.16 9.53 20 360687 1054 79382627
Jejunal perforation 13.15 9.53 12 360695 364 79383317
Blood gases abnormal 13.10 9.53 21 360686 1159 79382522
Blood creatine phosphokinase increased 13.09 9.53 215 360492 65875 79317806
Haemoglobinuria 13.07 9.53 17 360690 774 79382907
Sickle cell anaemia with crisis 13.07 9.53 10 360697 7912 79375769
Geotrichum infection 13.07 9.53 19 360688 962 79382719
Pancreatic carcinoma 13.07 9.53 26 360681 13551 79370130
Cough 13.05 9.53 1871 358836 364918 79018763
Hysterectomy 13.05 9.53 6 360701 6266 79377415
Dysgeusia 13.04 9.53 181 360526 56996 79326685
Cardiac pacemaker insertion 13.03 9.53 5 360702 5817 79377864
Renal cancer 13.03 9.53 22 360685 12204 79371477
Amoebic dysentery 13.01 9.53 5 360702 26 79383655
Japanese spotted fever 13.01 9.53 5 360702 26 79383655
Hepatic enzyme increased 13 9.53 684 360023 181926 79201755
Lower gastrointestinal haemorrhage 12.99 9.53 34 360673 16091 79367590
Encephalitis viral 12.98 9.53 33 360674 2546 79381135
Pelvic fracture 12.97 9.53 22 360685 12182 79371499
Thyroid stimulating immunoglobulin increased 12.96 9.53 7 360700 88 79383593
Lupus myocarditis 12.96 9.53 7 360700 88 79383593
Anxiety 12.96 9.53 958 359749 247554 79136127
Restlessness 12.94 9.53 141 360566 46351 79337330
Systemic infection 12.93 9.53 15 360692 9737 79373944
Central nervous system vasculitis 12.90 9.53 23 360684 1385 79382296
Glomerulonephritis membranoproliferative 12.90 9.53 15 360692 608 79383073
Fear of injection 12.90 9.53 9 360698 7465 79376216
Hallucination, auditory 12.89 9.53 49 360658 20644 79363037
Magnesium deficiency 12.88 9.53 15 360692 609 79383072
Arthritis fungal 12.87 9.53 8 360699 133 79383548
Infected varicose vein 12.86 9.53 5 360702 27 79383654
Drug dependence 12.86 9.53 120 360587 40649 79343032
Ketoacidosis 12.85 9.53 10 360697 7844 79375837
Arteritis coronary 12.85 9.53 6 360701 54 79383627
Hepatosplenomegaly 12.84 9.53 58 360649 6011 79377670
Expired product administered 12.83 9.53 8 360699 7043 79376638
Cervicitis 12.82 9.53 10 360697 243 79383438
Microangiopathic haemolytic anaemia 12.80 9.53 24 360683 1503 79382178
Allergy to chemicals 12.79 9.53 33 360674 2569 79381112
Malignant catatonia 12.78 9.53 13 360694 452 79383229
Lymphocyte count increased 12.78 9.53 57 360650 5875 79377806
Trichophytosis 12.77 9.53 12 360695 378 79383303
Tachypnoea 12.77 9.53 210 360497 31853 79351828
Polymenorrhoea 12.76 9.53 19 360688 983 79382698
Disseminated blastomycosis 12.75 9.53 9 360698 187 79383494
Mucosal disorder 12.72 9.53 40 360667 3488 79380193
Marrow hyperplasia 12.71 9.53 25 360682 1623 79382058
B-lymphocyte abnormalities 12.71 9.53 5 360702 28 79383653
Glomerular filtration rate increased 12.70 9.53 21 360686 1190 79382491
Basal cell carcinoma 12.67 9.53 108 360599 37267 79346414
Myasthenia gravis crisis 12.65 9.53 20 360687 1091 79382590
Graft versus host disease in lung 12.64 9.53 18 360689 894 79382787
Rheumatoid factor 12.62 9.53 12 360695 384 79383297
Infusion related hypersensitivity reaction 12.59 9.53 12 360695 385 79383296
Obesity 12.59 9.53 100 360607 35025 79348656
Delirium 12.58 9.53 289 360418 84338 79299343
Pneumonia aspiration 12.56 9.53 220 360487 66747 79316934
Herpes oesophagitis 12.54 9.53 12 360695 387 79383294
Porokeratosis 12.51 9.53 10 360697 252 79383429
Cryptococcal cutaneous infection 12.50 9.53 9 360698 193 79383488
Haemostasis 12.46 9.53 12 360695 390 79383291
Laboratory test abnormal 12.45 9.53 75 360632 27973 79355708
Balance disorder 12.43 9.53 346 360361 98511 79285170
Vein collapse 12.42 9.53 20 360687 1108 79382573
Nephropathy 12.39 9.53 81 360626 9657 79374024
Type 1 diabetes mellitus 12.37 9.53 63 360644 6856 79376825
Urine bilirubin increased 12.37 9.53 8 360699 143 79383538
Anaphylactoid reaction 12.37 9.53 53 360654 5369 79378312
Mitral valve incompetence 12.36 9.53 77 360630 28488 79355193
Diabetic macroangiopathy 12.32 9.53 8 360699 144 79383537
Gangrene 12.30 9.53 76 360631 8888 79374793
Incorrect route of product administration 12.26 9.53 100 360607 34829 79348852
Coronary artery aneurysm 12.23 9.53 8 360699 146 79383535
Ulcer 12.20 9.53 197 360510 29775 79353906
Enterococcal bacteraemia 12.20 9.53 36 360671 3032 79380649
Infectious pleural effusion 12.19 9.53 41 360666 3703 79379978
Adult T-cell lymphoma/leukaemia 12.18 9.53 11 360696 329 79383352
Campylobacter gastroenteritis 12.13 9.53 22 360685 1343 79382338
Inadequate aseptic technique in use of product 12.13 9.53 7 360700 101 79383580
Bulbar palsy 12.12 9.53 10 360697 264 79383417
Viral test positive 12.12 9.53 12 360695 404 79383277
Red blood cell elliptocytes present 12.11 9.53 9 360698 203 79383478
Dizziness postural 12.10 9.53 21 360686 11528 79372153
Anastomotic haemorrhage 12.06 9.53 10 360697 266 79383415
Blood 1,25-dihydroxycholecalciferol increased 12.02 9.53 5 360702 33 79383648
Cystitis 11.98 9.53 318 360389 52414 79331267
Gastric haemorrhage 11.92 9.53 32 360675 15018 79368663
Myelocyte count increased 11.90 9.53 16 360691 753 79382928
Diffuse mesangial sclerosis 11.89 9.53 6 360701 65 79383616
Drug tolerance 11.88 9.53 13 360694 8662 79375019
Hypoxia 11.85 9.53 576 360131 102667 79281014
Glomerulonephritis membranous 11.84 9.53 24 360683 1592 79382089
Respiratory disorder 11.83 9.53 276 360431 44580 79339101
Hepatic vein stenosis 11.81 9.53 6 360701 66 79383615
Dysarthria 11.79 9.53 225 360482 67397 79316284
Hypercapnia 11.79 9.53 75 360632 8860 79374821
Acne fulminans 11.78 9.53 9 360698 212 79383469
Atrial tachycardia 11.78 9.53 9 360698 7124 79376557
Arterial spasm 11.77 9.53 8 360699 156 79383525
Rib fracture 11.75 9.53 76 360631 27871 79355810
Urogenital disorder 11.73 9.53 6 360701 67 79383614
Interleukin level increased 11.72 9.53 14 360693 584 79383097
Microangiopathy 11.70 9.53 26 360681 1839 79381842
Inflammatory marker increased 11.70 9.53 86 360621 10654 79373027
Skin fissures 11.67 9.53 100 360607 12973 79370708
Hypocomplementaemia 11.67 9.53 9 360698 215 79383466
Diverticulum intestinal 11.67 9.53 13 360694 8592 79375089
Scleroderma renal crisis 11.66 9.53 14 360693 587 79383094
Toxic neuropathy 11.66 9.53 18 360689 962 79382719
Behaviour disorder 11.66 9.53 58 360649 6255 79377426
Encephalitis Japanese B 11.65 9.53 6 360701 68 79383613
Thrombosis in device 11.65 9.53 5 360702 5437 79378244
Vasculitis necrotising 11.61 9.53 21 360686 1279 79382402
Hypovolaemia 11.61 9.53 41 360666 17650 79366031
Mycobacterium kansasii infection 11.59 9.53 11 360696 351 79383330
Dermatitis acneiform 11.58 9.53 17 360690 9976 79373705
Coinfection 11.58 9.53 6 360701 69 79383612
Alveolar proteinosis 11.57 9.53 16 360691 773 79382908
Abnormal behaviour 11.57 9.53 107 360600 36314 79347367
Therapeutic product effect incomplete 11.56 9.53 523 360184 141122 79242559
Pruritus genital 11.56 9.53 3 360704 4483 79379198
Femoral neck fracture 11.55 9.53 17 360690 9967 79373714
Embolic stroke 11.54 9.53 11 360696 7815 79375866
Pathergy reaction 11.54 9.53 5 360702 37 79383644
Transaminases increased 11.46 9.53 311 360396 51432 79332249
Optic nerve compression 11.45 9.53 4 360703 15 79383666
Liver abscess 11.45 9.53 56 360651 5998 79377683
Pulmonary cavitation 11.44 9.53 24 360683 1632 79382049
Protein urine 11.42 9.53 23 360684 1519 79382162
Ophthalmoplegia 11.41 9.53 34 360673 2878 79380803
Anuria 11.41 9.53 145 360562 20818 79362863
Middle insomnia 11.39 9.53 36 360671 16033 79367648
Asymptomatic bacteriuria 11.39 9.53 11 360696 359 79383322
Activated partial thromboplastin time shortened 11.38 9.53 17 360690 882 79382799
Pulmonary necrosis 11.38 9.53 13 360694 517 79383164
Alanine aminotransferase abnormal 11.37 9.53 14 360693 8853 79374828
Infective myositis 11.34 9.53 8 360699 166 79383515
Tooth injury 11.32 9.53 27 360680 2001 79381680
Lip dry 11.32 9.53 34 360673 15384 79368297
Cardiogenic shock 11.31 9.53 128 360579 41786 79341895
Bundle branch block right 11.30 9.53 21 360686 11230 79372451
Granulocyte percentage 11.28 9.53 6 360701 73 79383608
Internal haemorrhage 11.27 9.53 14 360693 8819 79374862
Hepatic cyst infection 11.26 9.53 8 360699 168 79383513
Renal artery perforation 11.25 9.53 4 360703 16 79383665
Carotid artery insufficiency 11.25 9.53 4 360703 16 79383665
Granulomatous liver disease 11.24 9.53 21 360686 1312 79382369
Intentional dose omission 11.23 9.53 14 360693 8803 79374878
Alcohol interaction 11.22 9.53 4 360703 4870 79378811
Chronic papillomatous dermatitis 11.21 9.53 6 360701 74 79383607
Colitis ischaemic 11.18 9.53 34 360673 15325 79368356
Metabolic encephalopathy 11.16 9.53 15 360692 9132 79374549
Vascular rupture 11.15 9.53 24 360683 1661 79382020
Panic attack 11.15 9.53 64 360643 24152 79359529
Blood catecholamines abnormal 11.14 9.53 3 360704 3 79383678
Catheter site necrosis 11.14 9.53 3 360704 3 79383678
Osteoarthropathy 11.14 9.53 3 360704 3 79383678
Splenic necrosis 11.13 9.53 8 360699 171 79383510
Retching 11.12 9.53 41 360666 17426 79366255
Atrioventricular block second degree 11.11 9.53 10 360697 7302 79376379
Personality change 11.11 9.53 18 360689 10152 79373529
Cancer in remission 11.11 9.53 5 360702 41 79383640
Intestinal intraepithelial lymphocytes increased 11.09 9.53 8 360699 172 79383509
Haptoglobin decreased 11.08 9.53 21 360686 1326 79382355
Optic atrophy 11.08 9.53 26 360681 1907 79381774
Stent placement 11.06 9.53 8 360699 6512 79377169
Carotid artery stenosis 11.05 9.53 14 360693 8744 79374937
Nephritis 11.05 9.53 43 360664 4171 79379510
Nosocomial infection 11.04 9.53 33 360674 2799 79380882
Alcohol poisoning 11.02 9.53 4 360703 4817 79378864
Fibrin D dimer increased 11.02 9.53 72 360635 8582 79375099
Cytomegalovirus gastroenteritis 11.02 9.53 12 360695 452 79383229
Nail bed inflammation 10.98 9.53 13 360694 537 79383144
Myelitis transverse 10.95 9.53 26 360681 1921 79381760
Exercise tolerance decreased 10.94 9.53 15 360692 9056 79374625
Urinary fistula 10.87 9.53 6 360701 79 79383602
Hyperferritinaemia 10.86 9.53 15 360692 724 79382957
Genital herpes 10.84 9.53 27 360680 2057 79381624
Bradypnoea 10.83 9.53 7 360700 6045 79377636
Larynx irritation 10.83 9.53 7 360700 125 79383556
Excessive skin 10.83 9.53 7 360700 125 79383556
Disturbance in attention 10.82 9.53 163 360544 50638 79333043
Rash pruritic 10.82 9.53 244 360463 71385 79312296
Tearfulness 10.81 9.53 7 360700 6038 79377643
Glomerulonephropathy 10.80 9.53 10 360697 309 79383372
Disseminated cytomegaloviral infection 10.79 9.53 12 360695 463 79383218
Abdominal abscess 10.79 9.53 62 360645 7065 79376616
Prostatic specific antigen increased 10.78 9.53 19 360688 10367 79373314
Craniocerebral injury 10.77 9.53 5 360702 5191 79378490
Haematocrit decreased 10.75 9.53 358 360349 60954 79322727
Chronic hepatitis C 10.74 9.53 14 360693 639 79383042
Conjunctival oedema 10.72 9.53 19 360688 1139 79382542
Spinal operation 10.69 9.53 12 360695 7905 79375776
Mucocutaneous leishmaniasis 10.69 9.53 12 360695 468 79383213
T-lymphocyte count decreased 10.67 9.53 13 360694 554 79383127
Lower respiratory tract congestion 10.65 9.53 41 360666 3956 79379725
Feeling drunk 10.65 9.53 4 360703 4715 79378966
Arrhythmia 10.64 9.53 204 360503 61068 79322613
Enterocolitis bacterial 10.64 9.53 14 360693 645 79383036
Hepatitis viral 10.63 9.53 18 360689 1040 79382641
Creatinine urine increased 10.63 9.53 13 360694 556 79383125
Varices oesophageal 10.62 9.53 7 360700 5984 79377697
Viral load abnormal 10.61 9.53 6 360701 83 79383598
Aortic pseudoaneurysm 10.61 9.53 5 360702 46 79383635
Expanded disability status scale score increased 10.60 9.53 14 360693 647 79383034
Meniscus injury 10.60 9.53 9 360698 6759 79376922
Injury 10.59 9.53 268 360439 77228 79306453
Meningoencephalitis herpetic 10.59 9.53 26 360681 1963 79381718
Allergy to plants 10.55 9.53 15 360692 744 79382937
Foetal growth restriction 10.55 9.53 27 360680 2092 79381589
Hypertransaminasaemia 10.54 9.53 91 360616 11833 79371848
Skin test positive 10.53 9.53 19 360688 1155 79382526
Electric shock sensation 10.53 9.53 16 360691 843 79382838
Ear swelling 10.53 9.53 23 360684 1608 79382073
Acarodermatitis 10.53 9.53 21 360686 1377 79382304
Thyroxine free decreased 10.52 9.53 18 360689 1049 79382632
Human herpes virus 8 test positive 10.52 9.53 5 360702 47 79383634
Urine uric acid increased 10.52 9.53 5 360702 47 79383634
Hypertensive heart disease 10.48 9.53 3 360704 4203 79379478
Gastritis fungal 10.41 9.53 8 360699 190 79383491
Nasopharyngitis 10.39 9.53 1306 359401 252575 79131106
Endocarditis bacterial 10.38 9.53 22 360685 1507 79382174
Gastrointestinal perforation 10.37 9.53 55 360652 6082 79377599
Mouth ulceration 10.36 9.53 237 360470 38157 79345524
Swelling face 10.35 9.53 244 360463 70968 79312713
Hepatic artery stenosis 10.34 9.53 8 360699 192 79383489
Pharyngeal swelling 10.31 9.53 65 360642 7654 79376027
Tuberous sclerosis complex 10.31 9.53 6 360701 88 79383593
Haemoglobin abnormal 10.31 9.53 10 360697 7044 79376637
Bronchiolitis obliterans syndrome 10.29 9.53 10 360697 329 79383352
Central venous pressure increased 10.27 9.53 7 360700 137 79383544
Alternaria infection 10.26 9.53 14 360693 668 79383013
Accident 10.25 9.53 15 360692 8816 79374865
Cytomegalovirus test 10.25 9.53 5 360702 50 79383631
Metamyelocyte percentage increased 10.22 9.53 4 360703 22 79383659
Device failure 10.21 9.53 8 360699 6253 79377428
Pelvic pain 10.19 9.53 29 360678 13352 79370329
Abdominal pain 10.13 9.53 1577 359130 387992 78995689
Appendicitis 10.09 9.53 54 360653 20740 79362941
Drug-induced liver injury 10.09 9.53 380 360327 65737 79317944
Bacteroides infection 10.09 9.53 10 360697 337 79383344
Renal hypertrophy 10.08 9.53 5 360702 52 79383629
Extra dose administered 10.06 9.53 14 360693 8401 79375280
Mental impairment 10.06 9.53 48 360659 18988 79364693
Metastases to central nervous system 10.06 9.53 39 360668 16336 79367345
Candida test positive 10.05 9.53 18 360689 1088 79382593
Pulmonary arterial pressure increased 10.05 9.53 4 360703 4551 79379130
Retinal scar 10.05 9.53 11 360696 417 79383264
Prescription drug used without a prescription 10.02 9.53 3 360704 4082 79379599
Bone marrow reticulin fibrosis 10.02 9.53 10 360697 340 79383341
Nasal polyps 10.01 9.53 11 360696 7316 79376365
Conus medullaris syndrome 10 9.53 5 360702 53 79383628
Eye haemorrhage 9.99 9.53 18 360689 9739 79373942
Diabetic hyperosmolar coma 9.99 9.53 15 360692 782 79382899
Coombs direct test positive 9.98 9.53 11 360696 420 79383261
Ureteric obstruction 9.98 9.53 31 360676 2685 79380996
Plasmodium falciparum infection 9.96 9.53 6 360701 94 79383587
Infertility 9.96 9.53 14 360693 687 79382994
Foetal exposure during pregnancy 9.95 9.53 7 360700 5783 79377898
Neurological symptom 9.95 9.53 71 360636 8712 79374969
Incorrect product administration duration 9.95 9.53 25 360682 11997 79371684
Viral myocarditis 9.95 9.53 12 360695 506 79383175
Haemangioma-thrombocytopenia syndrome 9.94 9.53 3 360704 6 79383675
Osseous cryptococcosis 9.94 9.53 3 360704 6 79383675
Infusion site pain 9.94 9.53 103 360604 14073 79369608
Tuberculosis of genitourinary system 9.92 9.53 5 360702 54 79383627
Eosinopenia 9.92 9.53 5 360702 54 79383627
Donor specific antibody present 9.92 9.53 9 360698 271 79383410
Pseudopolyposis 9.91 9.53 6 360701 95 79383586
Cellulitis 9.88 9.53 398 360309 108662 79275019
Hepatic haemorrhage 9.86 9.53 17 360690 997 79382684
Vein disorder 9.85 9.53 48 360659 5134 79378547
Pericardial haemorrhage 9.83 9.53 4 360703 4491 79379190
Glucose-6-phosphate dehydrogenase deficiency 9.83 9.53 10 360697 348 79383333
Wrong technique in device usage process 9.81 9.53 3 360704 4025 79379656
Castleman's disease 9.80 9.53 4 360703 25 79383656
Tooth extraction 9.79 9.53 22 360685 10973 79372708
Dissociation 9.78 9.53 3 360704 4018 79379663
Foot operation 9.77 9.53 7 360700 5726 79377955
Eye infection fungal 9.74 9.53 12 360695 517 79383164
Gastrointestinal oedema 9.73 9.53 30 360677 2588 79381093
Iron deficiency anaemia 9.71 9.53 72 360635 25600 79358081
Ureteral necrosis 9.69 9.53 6 360701 99 79383582
Viral vasculitis 9.69 9.53 7 360700 151 79383530
Disseminated trichosporonosis 9.69 9.53 7 360700 151 79383530
Synovial fluid analysis 9.68 9.53 28 360679 2331 79381350
Complications of transplanted pancreas 9.67 9.53 4 360703 26 79383655
Hemiparesis 9.66 9.53 210 360497 33523 79350158
Haemorrhagic necrotic pancreatitis 9.65 9.53 7 360700 152 79383529
Colitis erosive 9.65 9.53 7 360700 152 79383529
Ventricular fibrillation 9.63 9.53 95 360612 31831 79351850
Pneumonia influenzal 9.63 9.53 32 360675 2872 79380809
CD4 lymphocytes decreased 9.62 9.53 30 360677 2604 79381077
Injection site inflammation 9.61 9.53 3 360704 3973 79379708
Bilirubin conjugated increased 9.60 9.53 50 360657 5489 79378192
Myelopathy 9.59 9.53 44 360663 4589 79379092
Hyperamylasaemia 9.58 9.53 18 360689 1129 79382552
Lung disorder 9.58 9.53 451 360256 80106 79303575
Pulse pressure increased 9.57 9.53 7 360700 154 79383527
Ejection fraction decreased 9.57 9.53 105 360602 34472 79349209
Allergy test positive 9.56 9.53 14 360693 714 79382967
Febrile neutropenia 9.55 9.53 907 359800 230092 79153589
Complications of transplanted heart 9.55 9.53 10 360697 360 79383321
Human papilloma virus test positive 9.55 9.53 12 360695 528 79383153

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
FDA MoA N0000175450 Corticosteroid Hormone Receptor Agonists
FDA EPC N0000175576 Corticosteroid
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D000932 Antiemetics
MeSH PA D002491 Central Nervous System Agents
MeSH PA D005765 Gastrointestinal Agents
MeSH PA D005938 Glucocorticoids
MeSH PA D006728 Hormones
MeSH PA D018696 Neuroprotective Agents
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D020011 Protective Agents
MeSH PA D000970 Antineoplastic Agents
MeSH PA D018931 Antineoplastic Agents, Hormonal
CHEBI has role CHEBI:35472 anti-inflammatory drugs
CHEBI has role CHEBI:35703 Xenobiotic
CHEBI has role CHEBI:37962 adrenergic agents
CHEBI has role CHEBI:50919 antiemetico
CHEBI has role CHEBI:63726 neuroprotective agents
CHEBI has role CHEBI:78298 environmental contaminants

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Nephrotic syndrome indication 52254009 DOID:1184




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.23 acidic
pKa2 12.63 acidic
pKa3 13.35 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Glucocorticoid receptor Nuclear hormone receptor AGONIST CHEMBL CHEMBL

External reference:

IDSource
4018069 VUID
N0000179635 NUI
D00751 KEGG_DRUG
2375-03-3 SECONDARY_CAS_RN
4018068 VANDF
4018069 VANDF
C0025819 UMLSCUI
CHEBI:135765 CHEBI
CHEBI:6888 CHEBI
CHEMBL1201265 ChEMBL_ID
CHEMBL1201081 ChEMBL_ID
DB14644 DRUGBANK_ID
16923 PUBCHEM_CID
DB00959 DRUGBANK_ID
203189 RXNORM
1041 MMSL
4854 MMSL
5093 MMSL
5095 MMSL
d00293 MMSL
002160 NDDF
002162 NDDF
005280 NDDF
116593003 SNOMEDCT_US
27242001 SNOMEDCT_US
412248005 SNOMEDCT_US
734654003 SNOMEDCT_US
D008776 MESH_DESCRIPTOR_UI
C0025815 UMLSCUI
732 INN_ID
6741 PUBCHEM_CID
D008775 MESH_DESCRIPTOR_UI
5GMR90S4KN UNII

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0003 INJECTION, POWDER, FOR SOLUTION 500 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0018 INJECTION, POWDER, FOR SOLUTION 1 g INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0039 INJECTION, POWDER, FOR SOLUTION 40 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0039 INJECTION, POWDER, FOR SOLUTION 40 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0047 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0047 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0698 INJECTION, POWDER, FOR SOLUTION 1 g INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0698 INJECTION, POWDER, FOR SOLUTION 1 g INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0758 INJECTION, POWDER, FOR SOLUTION 500 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0850 INJECTION, POWDER, FOR SOLUTION 2 g INTRAVENOUS NDA 22 sections
Methylprednisolone Sodium Succinate HUMAN PRESCRIPTION DRUG LABEL 1 0143-9753 INJECTION, POWDER, FOR SOLUTION 40 mg INTRAMUSCULAR ANDA 20 sections
Methylprednisolone Sodium Succinate HUMAN PRESCRIPTION DRUG LABEL 1 0143-9754 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAMUSCULAR ANDA 20 sections
Methylprednisolone Sodium Succinate HUMAN PRESCRIPTION DRUG LABEL 1 0143-9850 INJECTION, POWDER, FOR SOLUTION 500 mg INTRAMUSCULAR ANDA 22 sections
Methylprednisolone Sodium Succinate HUMAN PRESCRIPTION DRUG LABEL 1 0143-9851 INJECTION, POWDER, FOR SOLUTION 1 g INTRAMUSCULAR ANDA 22 sections
Solu-Medrol HUMAN PRESCRIPTION DRUG LABEL 1 0404-9957 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAVENOUS NDA 13 sections
Solu-Medrol HUMAN PRESCRIPTION DRUG LABEL 1 0404-9957 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAVENOUS NDA 13 sections
Solu-Medrol HUMAN PRESCRIPTION DRUG LABEL 1 0404-9958 INJECTION, POWDER, FOR SOLUTION 40 mg INTRAVENOUS NDA 13 sections
Solu-Medrol HUMAN PRESCRIPTION DRUG LABEL 1 0404-9958 INJECTION, POWDER, FOR SOLUTION 40 mg INTRAVENOUS NDA 13 sections
Methylprednisolone sodium succinate HUMAN PRESCRIPTION DRUG LABEL 1 43598-127 INJECTION 40 mg INTRAVENOUS ANDA 19 sections
Methylprednisolone sodium succinate HUMAN PRESCRIPTION DRUG LABEL 1 43598-128 INJECTION 500 mg INTRAVENOUS ANDA 19 sections
Methylprednisolone sodium succinate HUMAN PRESCRIPTION DRUG LABEL 1 43598-129 INJECTION 125 mg INTRAVENOUS ANDA 19 sections
Methylprednisolone sodium succinate HUMAN PRESCRIPTION DRUG LABEL 1 43598-130 INJECTION 1 g INTRAVENOUS ANDA 19 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 50090-0271 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 50090-0271 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 50090-2253 INJECTION, POWDER, FOR SOLUTION 40 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 51662-1263 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAMUSCULAR NDA 13 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 51662-1264 INJECTION, POWDER, FOR SOLUTION 40 mg INTRAMUSCULAR NDA 13 sections
SOLU-MEDROL(R) METHYLPREDNISOLONE SODIUM SUCCINAT HUMAN PRESCRIPTION DRUG LABEL 1 51662-1483 INJECTION, POWDER, FOR SOLUTION 500 mg INTRAMUSCULAR NDA 13 sections
Solu-Medrol HUMAN PRESCRIPTION DRUG LABEL 1 52584-039 INJECTION, POWDER, FOR SOLUTION 40 mg INTRAVENOUS NDA 13 sections
Solu-Medrol HUMAN PRESCRIPTION DRUG LABEL 1 52584-047 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAVENOUS NDA 14 sections