methylprednisolone succinate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
prednisone and prednisolone derivatives 1771 2921-57-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • methylprednisolone succinate
  • methylprednisolone hemisuccinate
  • methylprednisolone sodium succinate
A water-soluble ester of METHYLPREDNISOLONE used for cardiac, allergic, and hypoxic emergencies.
  • Molecular weight: 474.55
  • Formula: C26H34O8
  • CLOGP: 2.05
  • LIPINSKI: 0
  • HAC: 8
  • HDO: 3
  • TPSA: 138.20
  • ALOGS: -4.25
  • ROTB: 7

  • Status: OFP

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
May 18, 1959 FDA PHARMACIA AND UPJOHN

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Cytomegalovirus infection 747.80 9.48 585 189112 17377 50398050
Infusion related reaction 554.71 9.48 1642 188055 167915 50247512
Product use in unapproved indication 436.47 9.48 1181 188516 114638 50300789
Completed suicide 434.71 9.48 13 189684 131876 50283551
Off label use 388.39 9.48 3069 186628 471357 49944070
Blood pressure fluctuation 387.37 9.48 569 189128 35254 50380173
Lymphocyte count decreased 352.00 9.48 463 189234 25844 50389583
Oxygen saturation decreased 327.60 9.48 797 188900 72451 50342976
Urine abnormality 312.45 9.48 227 189470 6011 50409416
Product dose omission issue 308.14 9.48 152 189545 183686 50231741
Glossodynia 303.15 9.48 38 189659 115531 50299896
Blood pressure diastolic abnormal 289.95 9.48 257 189440 9104 50406323
Death 284.26 9.48 490 189207 324889 50090538
Alopecia 265.27 9.48 317 189380 244730 50170697
Posterior reversible encephalopathy syndrome 259.87 9.48 300 189397 14628 50400799
Blood pressure increased 258.38 9.48 1086 188611 132046 50283381
Pemphigus 256.17 9.48 67 189630 120099 50295328
Toxicity to various agents 254.18 9.48 253 189444 212246 50203181
Blood pressure systolic abnormal 253.61 9.48 219 189478 7487 50407940
Transplant rejection 251.31 9.48 240 189457 9369 50406058
Aspergillus infection 220.74 9.48 192 189505 6629 50408798
Multiple organ dysfunction syndrome 219.97 9.48 543 189154 49794 50365633
Drug ineffective for unapproved indication 218.51 9.48 330 189367 20951 50394476
Urinary sediment present 218.02 9.48 119 189578 1872 50413555
Urine leukocyte esterase positive 214.21 9.48 134 189563 2749 50412678
Throat irritation 211.67 9.48 395 189302 29844 50385583
Thrombotic microangiopathy 208.26 9.48 208 189489 8583 50406844
Abdominal discomfort 207.46 9.48 343 189354 231298 50184129
Red blood cells urine positive 206.23 9.48 129 189568 2646 50412781
Cytomegalovirus viraemia 203.81 9.48 157 189540 4552 50410875
White blood cells urine positive 194.58 9.48 151 189546 4427 50411000
Erythema 190.56 9.48 1065 188632 145349 50270078
Haemophagocytic lymphohistiocytosis 189.46 9.48 196 189501 8437 50406990
Swelling 188.76 9.48 288 189409 200584 50214843
Wound 187.18 9.48 81 189616 105713 50309714
Arthropathy 186.44 9.48 190 189507 157716 50257711
Bronchopulmonary aspergillosis 184.23 9.48 182 189515 7410 50408017
Blood pressure systolic increased 182.78 9.48 408 189289 35041 50380386
Contraindicated product administered 181.89 9.48 174 189523 148784 50266643
Systemic lupus erythematosus 181.55 9.48 156 189541 140466 50274961
Heart rate decreased 181.42 9.48 414 189283 36083 50379344
Fall 179.90 9.48 648 189049 334284 50081143
Polyomavirus-associated nephropathy 178.97 9.48 96 189601 1456 50413971
Crystal urine present 172.29 9.48 92 189605 1382 50414045
Kidney transplant rejection 168.35 9.48 131 189566 3856 50411571
Synovitis 166.58 9.48 132 189565 123733 50291694
Hand deformity 163.05 9.48 86 189611 100113 50315314
Drug abuse 161.04 9.48 18 189679 59828 50355599
Cytomegalovirus test positive 159.44 9.48 107 189590 2485 50412942
Injection site pain 158.73 9.48 111 189586 110913 50304514
Confusional state 156.66 9.48 286 189411 185642 50229785
Flushing 155.97 9.48 579 189118 66436 50348991
Intentional overdose 153.47 9.48 25 189672 62479 50352948
Drug intolerance 151.29 9.48 377 189320 218727 50196700
Heart rate increased 150.36 9.48 631 189066 76619 50338808
Pneumocystis jirovecii pneumonia 149.99 9.48 227 189470 14436 50400991
Complications of transplanted kidney 146.52 9.48 95 189602 2078 50413349
Blood pressure diastolic decreased 144.35 9.48 240 189457 16541 50398886
BK virus infection 142.37 9.48 104 189593 2777 50412650
Lymphopenia 141.93 9.48 229 189468 15392 50400035
Nocardiosis 141.69 9.48 85 189612 1613 50413814
Epstein-Barr virus infection 137.84 9.48 150 189547 6847 50408580
Pericarditis 136.41 9.48 62 189635 78627 50336800
Respiratory failure 134.72 9.48 687 189010 90494 50324933
Mucormycosis 132.70 9.48 94 189603 2389 50413038
Wrong technique in product usage process 130.20 9.48 25 189672 55485 50359942
Irritable bowel syndrome 129.88 9.48 19 189678 51422 50364005
Blood urine present 128.90 9.48 197 189500 12636 50402791
Cytomegalovirus infection reactivation 127.81 9.48 94 189603 2537 50412890
Neutrophil percentage increased 127.03 9.48 95 189602 2632 50412795
Discomfort 126.07 9.48 132 189565 108248 50307179
Lymphocyte percentage decreased 126.01 9.48 95 189602 2665 50412762
Post transplant lymphoproliferative disorder 125.39 9.48 113 189584 4091 50411336
Steroid diabetes 125.09 9.48 64 189633 876 50414551
Acute graft versus host disease in skin 124.92 9.48 98 189599 2920 50412507
Graft versus host disease 124.64 9.48 134 189563 6032 50409395
Multiple sclerosis relapse 123.28 9.48 398 189299 42566 50372861
Enterococcal infection 122.36 9.48 140 189557 6758 50408669
Hospitalisation 121.76 9.48 51 189646 67886 50347541
Red cell distribution width increased 121.26 9.48 155 189542 8404 50407023
Urine analysis abnormal 120.15 9.48 112 189585 4238 50411189
Pseudomonas infection 118.49 9.48 161 189536 9269 50406158
Cushingoid 118.10 9.48 135 189562 6510 50408917
Muscle injury 114.30 9.48 6 189691 37105 50378322
Delayed graft function 111.39 9.48 59 189638 871 50414556
Graft versus host disease in gastrointestinal tract 110.16 9.48 88 189609 2693 50412734
Diarrhoea 109.38 9.48 1552 188145 586924 49828503
Injection site erythema 106.98 9.48 75 189622 74861 50340566
Klebsiella infection 104.64 9.48 132 189565 7062 50408365
Graft versus host disease in skin 103.64 9.48 82 189615 2474 50412953
Varicella zoster virus infection 101.25 9.48 80 189617 2409 50413018
Duodenal ulcer perforation 99.91 9.48 24 189673 45587 50369840
Overdose 98.46 9.48 138 189559 99589 50315838
Anti-cyclic citrullinated peptide antibody positive 97.69 9.48 73 189624 70514 50344913
Acute respiratory distress syndrome 96.82 9.48 232 189465 20867 50394560
Bacterial test positive 96.10 9.48 103 189594 4620 50410807
Progressive multifocal leukoencephalopathy 96.06 9.48 162 189535 11295 50404132
Urine ketone body present 94.93 9.48 75 189622 2258 50413169
Bacterial test 94.17 9.48 57 189640 1100 50414327
Feeling hot 93.94 9.48 342 189355 38860 50376567
Rheumatoid factor positive 91.67 9.48 36 189661 49823 50365604
Device expulsion 90.89 9.48 4 189693 28818 50386609
Pyrexia 89.51 9.48 1957 187740 378246 50037181
Pneumomediastinum 89.23 9.48 55 189642 1098 50414329
Liver transplant rejection 87.66 9.48 57 189640 1253 50414174
Chest discomfort 87.17 9.48 621 189076 92101 50323326
Cardiac failure congestive 87.11 9.48 113 189584 84269 50331158
Pain 86.43 9.48 1590 188107 577313 49838114
Human herpesvirus 6 infection 85.62 9.48 74 189623 2532 50412895
Ear pruritus 85.58 9.48 73 189624 2453 50412974
Loss of personal independence in daily activities 85.24 9.48 82 189615 69968 50345459
Folliculitis 85.21 9.48 21 189676 39204 50376223
Haemoglobin urine present 85.02 9.48 47 189650 759 50414668
Adenovirus infection 84.49 9.48 80 189617 3088 50412339
Culture urine positive 84.23 9.48 83 189614 3368 50412059
Immunodeficiency 82.48 9.48 176 189521 14652 50400775
Dehydration 82.27 9.48 294 189403 152155 50263272
Fatigue 82.21 9.48 2024 187673 705577 49709850
Helicobacter infection 81.80 9.48 42 189655 49660 50365767
Acinetobacter infection 80.87 9.48 56 189641 1371 50414056
Acute graft versus host disease in intestine 80.61 9.48 59 189638 1580 50413847
Septic shock 79.71 9.48 424 189273 56751 50358676
Reversible cerebral vasoconstriction syndrome 79.59 9.48 65 189632 2054 50413373
Adverse drug reaction 77.85 9.48 56 189641 55166 50360261
Suicide attempt 77.57 9.48 49 189648 51683 50363744
Peripheral swelling 76.70 9.48 455 189242 205481 50209946
Osteonecrosis 76.17 9.48 221 189476 22296 50393131
Temperature regulation disorder 75.33 9.48 86 189611 4141 50411286
Myocardial infarction 73.08 9.48 139 189558 88888 50326539
Protein urine present 72.46 9.48 95 189602 5282 50410145
Psoriasis 71.63 9.48 92 189605 68908 50346519
Acute graft versus host disease 67.96 9.48 79 189618 3879 50411548
Pneumatosis intestinalis 67.65 9.48 59 189638 2044 50413383
Multiple sclerosis 67.28 9.48 199 189498 20294 50395133
Neutrophil count increased 67.20 9.48 158 189539 14037 50401390
Electric shock 67.01 9.48 44 189653 984 50414443
Vomiting 66.94 9.48 1271 188426 459487 49955940
Cytomegalovirus chorioretinitis 66.87 9.48 51 189646 1456 50413971
Viral haemorrhagic cystitis 66.55 9.48 38 189659 655 50414772
Blood pressure diastolic increased 66.09 9.48 108 189589 7335 50408092
Intentional product use issue 65.92 9.48 504 189193 76414 50339013
Disseminated intravascular coagulation 65.67 9.48 176 189521 16959 50398468
Respiratory rate increased 65.49 9.48 137 189560 11248 50404179
Pulmonary alveolar haemorrhage 65.21 9.48 78 189619 3949 50411478
Serotonin syndrome 65.06 9.48 8 189689 24705 50390722
Hyponatraemia 64.26 9.48 168 189529 95971 50319456
Specific gravity urine decreased 64.18 9.48 37 189660 650 50414777
Pneumonia cytomegaloviral 63.53 9.48 55 189642 1886 50413541
Disease recurrence 63.09 9.48 192 189505 19889 50395538
Drug resistance 62.91 9.48 185 189512 18804 50396623
Chorioretinopathy 62.90 9.48 39 189658 787 50414640
Knee arthroplasty 62.49 9.48 28 189669 35818 50379609
Immunosuppressant drug level increased 62.33 9.48 67 189630 3015 50412412
Accidental exposure to product 61.85 9.48 7 189690 23050 50392377
Epstein-Barr virus associated lymphoproliferative disorder 61.74 9.48 51 189646 1638 50413789
Infective aneurysm 61.46 9.48 30 189667 369 50415058
Sepsis 61.44 9.48 765 188932 132160 50283267
Intervertebral discitis 61.36 9.48 62 189635 2594 50412833
Stomatitis 61.16 9.48 186 189511 101158 50314269
Escherichia infection 61.01 9.48 130 189567 10811 50404616
Oedema peripheral 60.93 9.48 345 189352 157616 50257811
Injection site swelling 60.68 9.48 41 189656 41732 50373695
Decreased appetite 59.88 9.48 474 189223 200449 50214978
Myopathy 59.76 9.48 116 189581 9023 50406404
Cerebrovascular accident 59.14 9.48 171 189526 94509 50320918
Psoriatic arthropathy 58.45 9.48 54 189643 46978 50368449
Monocyte count increased 58.42 9.48 87 189610 5452 50409975
Immune thrombocytopenia 58.41 9.48 114 189583 8903 50406524
Staphylococcal sepsis 58.34 9.48 99 189598 6937 50408490
Injection site pruritus 58.25 9.48 40 189657 40371 50375056
Cytomegalovirus colitis 57.87 9.48 52 189645 1875 50413552
Urticaria 56.63 9.48 738 188959 128823 50286604
Human herpesvirus 8 infection 56.60 9.48 24 189673 207 50415220
Nitrite urine present 56.38 9.48 38 189659 889 50414538
Premature delivery 56.31 9.48 206 189491 23457 50391970
Herpes simplex 55.75 9.48 98 189599 7064 50408363
Product quality issue 55.55 9.48 23 189674 30835 50384592
Blood thyroid stimulating hormone decreased 55.12 9.48 73 189624 4099 50411328
Systemic mycosis 55.11 9.48 40 189657 1057 50414370
Hypoglycaemia 55.03 9.48 72 189625 53509 50361918
Ureaplasma infection 54.07 9.48 30 189667 488 50414939
Tachycardia 54.02 9.48 592 189105 99171 50316256
Leukopenia 53.74 9.48 435 189262 67093 50348334
Enterobacter infection 52.89 9.48 49 189648 1839 50413588
Injection site reaction 52.66 9.48 66 189631 49966 50365461
Cystitis haemorrhagic 52.37 9.48 67 189630 3635 50411792
Systemic candida 51.82 9.48 58 189639 2732 50412695
Thrombocytopenia 51.57 9.48 717 188980 126956 50288471
Orthostatic hypotension 51.43 9.48 23 189674 29458 50385969
Febrile bone marrow aplasia 51.27 9.48 88 189609 6223 50409204
Candida infection 51.19 9.48 199 189498 23324 50392103
Nausea 50.87 9.48 2146 187551 703252 49712175
Lower respiratory tract infection 50.40 9.48 185 189512 95016 50320411
Monocyte percentage increased 50.13 9.48 37 189660 1004 50414423
Acute graft versus host disease in liver 49.51 9.48 30 189667 580 50414847
Serum sickness 49.38 9.48 54 189643 2478 50412949
Intentional self-injury 48.99 9.48 13 189684 23099 50392328
Adverse event 48.97 9.48 55 189642 43708 50371719
Red blood cells urine 48.92 9.48 28 189669 485 50414942
Substance-induced psychotic disorder 48.91 9.48 44 189653 1589 50413838
Constipation 48.66 9.48 453 189244 185255 50230172
Osteonecrosis of jaw 48.50 9.48 31 189666 32495 50382932
Mean cell haemoglobin decreased 48.37 9.48 61 189636 3262 50412165
Hypogammaglobulinaemia 48.33 9.48 81 189616 5618 50409809
Drug hypersensitivity 48.16 9.48 657 189040 250353 50165074
Vasculitis 47.98 9.48 138 189559 13853 50401574
Hypertension 47.61 9.48 1081 188616 210122 50205305
Blister 47.21 9.48 163 189534 85255 50330172
Dizziness 47.02 9.48 966 188731 345403 50070024
Strongyloidiasis 47.02 9.48 33 189664 826 50414601
Central nervous system viral infection 46.94 9.48 17 189680 91 50415336
Intentional product misuse 46.77 9.48 64 189633 46670 50368757
Thyroxine free increased 46.73 9.48 32 189665 769 50414658
C-reactive protein abnormal 46.50 9.48 23 189674 27786 50387641
Gastrointestinal disorder 46.50 9.48 189 189508 94267 50321160
Sedation 45.88 9.48 29 189668 30581 50384846
Therapy cessation 45.84 9.48 20 189677 25991 50389436
Lupus nephritis 45.54 9.48 50 189647 2305 50413122
Therapy interrupted 45.33 9.48 10 189687 20142 50395285
Syncope 45.31 9.48 215 189482 102787 50312640
Listeriosis 45.26 9.48 39 189658 1329 50414098
Granulomatosis with polyangiitis 45.25 9.48 44 189653 1756 50413671
Product use issue 44.80 9.48 352 189345 149123 50266304
Status epilepticus 44.78 9.48 131 189566 13275 50402152
Injection site bruising 44.77 9.48 43 189654 36725 50378702
Intra-abdominal pressure increased 44.68 9.48 20 189677 199 50415228
Food allergy 44.58 9.48 96 189601 8041 50407386
Chronic graft versus host disease 43.93 9.48 54 189643 2813 50412614
Body temperature decreased 43.55 9.48 148 189549 16247 50399180
Bacteraemia 43.48 9.48 136 189561 14297 50401130
Anaphylactic shock 43.44 9.48 170 189527 19985 50395442
Proteinuria 42.49 9.48 148 189549 16449 50398978
West Nile viral infection 42.46 9.48 23 189674 356 50415071
Therapeutic product effect decreased 41.89 9.48 318 189379 135732 50279695
Mycoplasma infection 41.19 9.48 23 189674 379 50415048
Intensive care unit acquired weakness 41.03 9.48 28 189669 669 50414758
Pharyngeal paraesthesia 40.91 9.48 38 189659 1431 50413996
Hepatocellular injury 40.75 9.48 199 189498 25748 50389679
Mycobacterium abscessus infection 40.25 9.48 25 189672 506 50414921
Hip arthroplasty 40.15 9.48 33 189664 30396 50385031
Toxoplasmosis 40.13 9.48 37 189660 1380 50414047
Human bocavirus infection 39.86 9.48 22 189675 354 50415073
Pneumatosis 39.70 9.48 23 189674 408 50415019
Cytokine release syndrome 39.67 9.48 95 189602 8539 50406888
COVID-19 39.54 9.48 305 189392 46357 50369070
Nephrotic syndrome 39.39 9.48 67 189630 4703 50410724
Systemic inflammatory response syndrome 39.19 9.48 69 189628 4980 50410447
Hyperglycaemia 39.07 9.48 252 189445 36153 50379274
Central nervous system infection 38.81 9.48 27 189670 666 50414761
International normalised ratio increased 38.44 9.48 64 189633 43088 50372339
Surgery 38.34 9.48 34 189663 30171 50385256
Haemolytic anaemia 38.22 9.48 98 189599 9194 50406233
Necrotising herpetic retinopathy 37.90 9.48 14 189683 80 50415347
Pulmonary mucormycosis 37.86 9.48 18 189679 208 50415219
Red blood cell count increased 37.82 9.48 48 189649 2583 50412844
Cerebral aspergillosis 37.61 9.48 21 189676 346 50415081
Contusion 37.54 9.48 256 189441 111927 50303500
Diabetes mellitus 37.47 9.48 313 189384 48720 50366707
Device issue 37.40 9.48 14 189683 19958 50395469
Herpes zoster 37.37 9.48 418 189279 70368 50345059
Chronic allograft nephropathy 37.35 9.48 26 189671 642 50414785
Encephalitis cytomegalovirus 37.29 9.48 24 189673 518 50414909
Malignant neoplasm progression 36.97 9.48 131 189566 67993 50347434
Joint swelling 36.94 9.48 672 189025 244614 50170813
Stenotrophomonas infection 36.81 9.48 38 189659 1631 50413796
Pleocytosis 36.58 9.48 24 189673 536 50414891
Adrenal insufficiency 36.46 9.48 127 189570 14116 50401311
Mean cell volume decreased 36.28 9.48 47 189650 2582 50412845
C-reactive protein increased 36.22 9.48 395 189302 66079 50349348
Pain in extremity 36.11 9.48 764 188933 272101 50143326
Accidental overdose 36.07 9.48 14 189683 19519 50395908
General physical health deterioration 35.78 9.48 351 189346 142083 50273344
Feeding intolerance 35.76 9.48 23 189674 496 50414931
Product prescribing error 35.56 9.48 17 189680 20944 50394483
Hypofibrinogenaemia 35.37 9.48 31 189666 1081 50414346
Gastroenteritis norovirus 35.37 9.48 38 189659 1709 50413718
Glomerulonephritis 35.30 9.48 36 189661 1523 50413904
Demyelination 35.23 9.48 73 189624 5953 50409474
Urinary casts 35.20 9.48 25 189672 638 50414789
Bone pain 35.13 9.48 78 189619 47151 50368276
Pedal pulse abnormal 35.11 9.48 15 189682 132 50415295
Device malfunction 35.05 9.48 7 189690 15114 50400313
Symptom masked 35.00 9.48 25 189672 644 50414783
Blood calcium decreased 34.81 9.48 17 189680 20689 50394738
Oral herpes 34.76 9.48 162 189535 20563 50394864
Renal transplant failure 34.61 9.48 24 189673 589 50414838
Drug interaction 34.58 9.48 533 189164 199088 50216339
Nephropathy toxic 34.40 9.48 86 189611 7943 50407484
Band sensation 34.30 9.48 25 189672 665 50414762
Lower limb fracture 34.29 9.48 6 189691 14240 50401187
Bronchospasm 34.24 9.48 128 189569 14726 50400701
JC virus infection 34.17 9.48 38 189659 1777 50413650
Impaired healing 34.11 9.48 140 189557 69646 50345781
Coeliac disease 34.08 9.48 90 189607 8595 50406832
Optic neuritis 34.05 9.48 78 189619 6812 50408615
Candida sepsis 33.80 9.48 32 189665 1235 50414192
Product substitution issue 33.66 9.48 6 189691 14051 50401376
Rash erythematous 33.64 9.48 235 189462 34617 50380810
Incorrect dose administered 33.58 9.48 83 189614 48331 50367096
Poor venous access 33.55 9.48 100 189597 10240 50405187
Thunderclap headache 33.53 9.48 15 189682 149 50415278
Mobility decreased 33.35 9.48 170 189527 79778 50335649
Herpes virus infection 33.20 9.48 63 189634 4818 50410609
Urine leukocyte esterase 33.19 9.48 14 189683 119 50415308
Depressed level of consciousness 33.04 9.48 93 189604 51860 50363567
Injection site warmth 33.03 9.48 6 189691 13860 50401567
COVID-19 pneumonia 32.95 9.48 87 189610 8308 50407119
Brain abscess 32.87 9.48 37 189660 1754 50413673
Disseminated tuberculosis 32.79 9.48 44 189653 2502 50412925
Macular degeneration 32.65 9.48 7 189690 14381 50401046
Encephalitis 32.62 9.48 80 189617 7300 50408127
Segmental diverticular colitis 32.60 9.48 14 189683 125 50415302
Hepatic function abnormal 32.51 9.48 222 189475 32459 50382968
Infection reactivation 32.37 9.48 28 189669 959 50414468
Full blood count decreased 32.36 9.48 22 189675 22324 50393103
Shock haemorrhagic 32.27 9.48 86 189611 8258 50407169
Rebound effect 32.08 9.48 49 189648 3140 50412287
Cataract 32.02 9.48 294 189403 47006 50368421
Graft versus host disease in liver 31.85 9.48 21 189676 473 50414954
Cytomegalovirus enterocolitis 31.47 9.48 22 189675 547 50414880
Red blood cell sedimentation rate abnormal 31.38 9.48 11 189686 16332 50399095
Haemolytic uraemic syndrome 31.29 9.48 41 189656 2278 50413149
Cells in urine 31.20 9.48 15 189682 178 50415249
Pregnancy 31.14 9.48 39 189658 29538 50385889
Laryngeal stenosis 31.10 9.48 25 189672 772 50414655
Lethargy 31.06 9.48 89 189608 49343 50366084
Neuroleptic malignant syndrome 30.83 9.48 3 189694 11127 50404300
Pancytopenia 30.78 9.48 464 189233 83566 50331861
Sleep disorder 30.52 9.48 111 189586 57172 50358255
Epstein-Barr virus infection reactivation 30.44 9.48 21 189676 511 50414916
Transient ischaemic attack 30.37 9.48 46 189651 32164 50383263
Swollen joint count increased 30.35 9.48 9 189688 14864 50400563
Smear cervix abnormal 30.28 9.48 44 189653 2697 50412730
Rhabdomyolysis 30.24 9.48 63 189634 38964 50376463
Encephalitis autoimmune 30.23 9.48 30 189667 1228 50414199
Memory impairment 30.21 9.48 174 189523 79186 50336241
Gastroenteritis rotavirus 30.18 9.48 13 189684 117 50415310
Necrotising retinitis 30.14 9.48 17 189680 286 50415141
Secondary immunodeficiency 29.79 9.48 29 189668 1159 50414268
Monocyte count decreased 29.67 9.48 36 189661 1850 50413577
Opportunistic infection 29.66 9.48 34 189663 1644 50413783
Breast cancer 29.38 9.48 74 189623 42816 50372611
Calcium ionised decreased 29.24 9.48 16 189681 253 50415174
Quadriparesis 29.04 9.48 34 189663 1682 50413745
Q fever 28.93 9.48 11 189686 69 50415358
Blood immunoglobulin M decreased 28.90 9.48 23 189674 700 50414727
Dermatomyositis 28.84 9.48 38 189659 2123 50413304
Leukoencephalopathy 28.77 9.48 52 189645 3831 50411596
Hepatic enzyme increased 28.74 9.48 353 189344 137027 50278400
Hypophagia 28.74 9.48 37 189660 27691 50387736
Suicidal ideation 28.41 9.48 109 189588 55276 50360151
Pulmonary haemorrhage 28.30 9.48 70 189627 6422 50409005
Poisoning 28.30 9.48 6 189691 12423 50403004
Treatment failure 28.28 9.48 355 189342 137282 50278145
Aspergillosis oral 28.17 9.48 10 189687 50 50415377
Glomerulosclerosis 27.68 9.48 17 189680 337 50415090
Unresponsive to stimuli 27.63 9.48 45 189652 30564 50384863
Product storage error 27.63 9.48 6 189691 12218 50403209
CSF protein increased 27.62 9.48 19 189678 460 50414967
Herpes simplex colitis 27.54 9.48 6 189691 0 50415427
Rheumatoid arthritis 27.47 9.48 972 188725 201578 50213849
Plasma cell myeloma 27.40 9.48 47 189650 31275 50384152
Gastrooesophageal reflux disease 27.29 9.48 171 189526 76257 50339170
Inappropriate schedule of product administration 27.07 9.48 158 189539 71673 50343754
Transplant failure 26.98 9.48 30 189667 1403 50414024
Diffuse large B-cell lymphoma 26.77 9.48 63 189634 5599 50409828
Listeria encephalitis 26.77 9.48 15 189682 249 50415178
Rheumatic fever 26.65 9.48 15 189682 16852 50398575
Device difficult to use 26.52 9.48 3 189694 9883 50405544
Malignant catatonia 26.50 9.48 12 189685 123 50415304
Central nervous system lymphoma 26.43 9.48 29 189668 1336 50414091
Band neutrophil percentage increased 26.41 9.48 14 189683 207 50415220
Oral pruritus 26.35 9.48 32 189665 1646 50413781
Natural killer-cell leukaemia 26.34 9.48 11 189686 91 50415336
Hepatitis 26.32 9.48 205 189492 31248 50384179
Diffuse alveolar damage 26.32 9.48 23 189674 799 50414628
Bacterial sepsis 26.29 9.48 48 189649 3564 50411863
Colitis ulcerative 26.28 9.48 129 189568 16725 50398702
Therapeutic product effect incomplete 26.25 9.48 218 189479 91297 50324130
Lip pruritus 26.25 9.48 22 189675 721 50414706
Staphylococcal bacteraemia 26.10 9.48 57 189640 4820 50410607
Injection site haemorrhage 25.94 9.48 25 189672 21321 50394106
Abscess 25.75 9.48 114 189583 14158 50401269
Neuralgia 25.74 9.48 155 189542 21708 50393719
Polyomavirus viraemia 25.73 9.48 18 189679 448 50414979
Aplasia 25.67 9.48 49 189648 3764 50411663
Mean cell haemoglobin concentration increased 25.66 9.48 18 189679 450 50414977
Coronary artery disease 25.64 9.48 45 189652 29681 50385746
Cerebral artery stenosis 25.62 9.48 17 189680 387 50415040
Alveolitis 25.58 9.48 39 189658 2495 50412932
Intestinal perforation 25.58 9.48 92 189605 10387 50405040
Temperature intolerance 25.50 9.48 74 189623 7465 50407962
Skin fissures 25.49 9.48 81 189616 8587 50406840
Sense of oppression 25.46 9.48 24 189673 921 50414506
Unevaluable event 25.38 9.48 88 189609 45978 50369449
Engraft failure 25.33 9.48 16 189681 334 50415093
Leukocyturia 25.30 9.48 25 189672 1018 50414409
Pyelonephritis fungal 25.25 9.48 11 189686 102 50415325
Anti-thyroid antibody positive 25.17 9.48 17 189680 399 50415028
Escherichia urinary tract infection 25.16 9.48 91 189606 10304 50405123
Steroid dependence 25.12 9.48 16 189681 339 50415088
Blood albumin increased 25.08 9.48 23 189674 852 50414575
Immunosuppressant drug level decreased 25.08 9.48 23 189674 852 50414575
Pain in jaw 25.02 9.48 68 189629 38360 50377067
Parvovirus B19 infection 25.02 9.48 18 189679 469 50414958
Staphylococcal infection 24.93 9.48 223 189474 35393 50380034
Liver function test abnormal 24.90 9.48 84 189613 44255 50371172
Factor XIII deficiency 24.90 9.48 10 189687 74 50415353
White blood cell count increased 24.88 9.48 255 189442 41985 50373442
Escherichia sepsis 24.83 9.48 52 189645 4272 50411155
Blood thyroid stimulating hormone increased 24.80 9.48 64 189633 6028 50409399
Rash 24.65 9.48 1365 188332 436106 49979321
Haemoglobin urine 24.62 9.48 11 189686 109 50415318
Anorectal ulcer 24.58 9.48 9 189688 50 50415377
Faecal volume decreased 24.55 9.48 12 189685 148 50415279
Type I hypersensitivity 24.50 9.48 37 189660 2348 50413079
Renal tubular atrophy 24.36 9.48 19 189678 561 50414866
Choroiditis 24.35 9.48 11 189686 112 50415315
Chills 24.34 9.48 503 189194 96184 50319243
Acute myeloid leukaemia recurrent 24.30 9.48 28 189669 1362 50414065
Acute pulmonary oedema 24.26 9.48 71 189626 7196 50408231
Specific gravity urine increased 24.24 9.48 13 189684 197 50415230
Pulmonary hypertension 24.19 9.48 56 189641 33361 50382066
Device dislocation 24.19 9.48 27 189670 21519 50393908
Tri-iodothyronine free increased 24.18 9.48 13 189684 198 50415229
Non-consummation 24.14 9.48 9 189688 53 50415374
Quadriplegia 24.09 9.48 31 189666 1692 50413735
Red cell distribution width decreased 24.09 9.48 25 189672 1080 50414347
Hyperammonaemia 23.92 9.48 54 189643 4670 50410757
Malacoplakia vesicae 23.86 9.48 9 189688 55 50415372
Herpes simplex oesophagitis 23.77 9.48 11 189686 119 50415308
Body temperature fluctuation 23.75 9.48 33 189664 1940 50413487
Osteoarthritis 23.72 9.48 155 189542 68451 50346976
Mean cell haemoglobin increased 23.60 9.48 35 189662 2185 50413242
Pyelonephritis 23.56 9.48 115 189582 14874 50400553
Creatinine urine decreased 23.53 9.48 12 189685 163 50415264
Myelitis 23.52 9.48 26 189671 1208 50414219
Respiratory distress 23.49 9.48 195 189502 30294 50385133
Chronic graft versus host disease in liver 23.41 9.48 14 189683 264 50415163
Mean cell haemoglobin concentration decreased 23.40 9.48 40 189657 2819 50412608
Injection site mass 23.30 9.48 15 189682 15665 50399762
Product complaint 23.28 9.48 7 189690 11459 50403968
Therapy non-responder 23.26 9.48 293 189404 50729 50364698
Cytomegalovirus enteritis 23.24 9.48 13 189684 215 50415212
Perforation 23.18 9.48 23 189674 941 50414486
Cough 23.14 9.48 1116 188581 240148 50175279
Blood creatinine decreased 23.13 9.48 55 189642 4921 50410506
Ulcer 23.02 9.48 142 189555 20058 50395369
Cestode infection 23 9.48 14 189683 273 50415154
Drug level decreased 22.94 9.48 65 189632 6468 50408959
Enterococcus test positive 22.87 9.48 24 189673 1050 50414377
Orbital apex syndrome 22.87 9.48 8 189689 38 50415389
Partial seizures 22.86 9.48 54 189643 4811 50410616
Viraemia 22.86 9.48 24 189673 1051 50414376
Rubella antibody positive 22.83 9.48 9 189688 63 50415364
Pneumocystis jirovecii infection 22.82 9.48 26 189671 1249 50414178
Torsade de pointes 22.66 9.48 8 189689 11827 50403600
Corynebacterium infection 22.61 9.48 16 189681 406 50415021
Drug withdrawal syndrome 22.52 9.48 37 189660 25044 50390383
Abdominal pain upper 22.24 9.48 442 189255 158867 50256560
Injection site urticaria 22.16 9.48 9 189688 12208 50403219
Cerebral venous thrombosis 22.09 9.48 31 189666 1840 50413587
Injection site rash 22.03 9.48 17 189680 16160 50399267
Neuropathy peripheral 22.01 9.48 244 189453 96513 50318914
Tri-iodothyronine free decreased 22.01 9.48 14 189683 296 50415131
Bone marrow failure 21.99 9.48 178 189519 27446 50387981
Haematocrit decreased 21.98 9.48 214 189483 34762 50380665
Oral candidiasis 21.92 9.48 123 189574 16792 50398635
Bacillus infection 21.83 9.48 17 189680 501 50414926
Muir-Torre syndrome 21.80 9.48 7 189690 24 50415403
Femur fracture 21.71 9.48 70 189627 37394 50378033
Osteomyelitis fungal 21.69 9.48 6 189691 10 50415417
Chronic graft versus host disease in skin 21.62 9.48 19 189678 665 50414762
Steroid withdrawal syndrome 21.57 9.48 17 189680 510 50414917
Joint tuberculosis 21.55 9.48 10 189687 109 50415318
Premenstrual syndrome 21.38 9.48 18 189679 594 50414833
Pathogen resistance 21.36 9.48 58 189639 5631 50409796
Blood glucose decreased 21.36 9.48 22 189675 18189 50397238
Oropharyngeal pain 21.34 9.48 410 189287 77391 50338036
Right ventricular failure 21.26 9.48 17 189680 15876 50399551
Central nervous system lesion 21.23 9.48 81 189616 9408 50406019
Infection 21.20 9.48 490 189207 172464 50242963
Epstein-Barr virus associated lymphoma 21.09 9.48 16 189681 453 50414974
Disseminated varicella zoster vaccine virus infection 21.06 9.48 8 189689 50 50415377
Cryptococcosis 21.01 9.48 21 189676 867 50414560
Cerebellar stroke 21.01 9.48 12 189685 207 50415220
Engraftment syndrome 20.98 9.48 14 189683 322 50415105
Throat tightness 20.97 9.48 142 189555 20705 50394722
Lichen sclerosus 20.96 9.48 22 189675 963 50414464
Perinephric abscess 20.91 9.48 11 189686 160 50415267
Magnetic resonance imaging abnormal 20.91 9.48 37 189660 2681 50412746
Serratia infection 20.74 9.48 20 189677 790 50414637
Blood immunoglobulin G decreased 20.68 9.48 31 189666 1954 50413473
Neuropsychiatric lupus 20.67 9.48 11 189686 164 50415263
Pulmonary nocardiosis 20.61 9.48 11 189686 165 50415262
B-lymphocyte count decreased 20.58 9.48 21 189676 889 50414538
Encephalopathy 20.57 9.48 205 189492 33506 50381921
Post-traumatic stress disorder 20.48 9.48 48 189649 4255 50411172
Band neutrophil count increased 20.42 9.48 14 189683 337 50415090
Rhesus antigen positive 20.41 9.48 10 189687 124 50415303
Drug ineffective 20.41 9.48 3429 186268 815904 49599523
Multiple-drug resistance 20.38 9.48 41 189656 3273 50412154
Hairy cell leukaemia 20.37 9.48 6 189691 14 50415413
Fungaemia 20.36 9.48 31 189666 1981 50413446
Myelocyte count increased 20.35 9.48 14 189683 339 50415088
Ultrasound ovary abnormal 20.33 9.48 9 189688 87 50415340
Peritonitis 20.33 9.48 113 189584 15373 50400054
Body temperature increased 20.30 9.48 193 189504 31148 50384279
Cytomegalovirus gastrointestinal infection 20.18 9.48 13 189684 281 50415146
CSF measles antibody positive 20.18 9.48 8 189689 57 50415370
Graft versus host disease in lung 20.17 9.48 14 189683 344 50415083
Muscle spasms 20.14 9.48 340 189357 125213 50290214
Urobilinogen urine increased 20.08 9.48 12 189685 226 50415201
Antinuclear antibody 20.02 9.48 16 189681 490 50414937
Hepatitis toxic 19.96 9.48 37 189660 2779 50412648
Biloma 19.94 9.48 8 189689 59 50415368
Coma 19.92 9.48 128 189569 56751 50358676
Treatment noncompliance 19.89 9.48 53 189644 30097 50385330
Myelopathy 19.88 9.48 35 189662 2526 50412901
Hypotension 19.88 9.48 1076 188621 234393 50181034
Urinary tract candidiasis 19.85 9.48 16 189681 496 50414931
Neurosarcoidosis 19.82 9.48 11 189686 179 50415248
Gait disturbance 19.81 9.48 420 189277 149585 50265842
Acute kidney injury 19.80 9.48 678 189019 227380 50188047
Clostridium difficile colitis 19.76 9.48 124 189573 17618 50397809
Hepatic cirrhosis 19.76 9.48 22 189675 17555 50397872
Feeling abnormal 19.75 9.48 341 189356 125151 50290276
IgA nephropathy 19.73 9.48 15 189682 426 50415001
Eosinophil percentage increased 19.68 9.48 21 189676 937 50414490
Metastases to liver 19.65 9.48 28 189669 20076 50395351
Full blood count abnormal 19.64 9.48 36 189661 23352 50392075
Birdshot chorioretinopathy 19.60 9.48 8 189689 62 50415365
Meningoencephalitis viral 19.48 9.48 13 189684 299 50415128
Paralysis 19.42 9.48 74 189623 8590 50406837
Hepatic cyst infection 19.40 9.48 9 189688 98 50415329
Urinary tract infection bacterial 19.36 9.48 46 189651 4113 50411314
Hepatic necrosis 19.20 9.48 53 189644 5195 50410232
Meningoencephalitis bacterial 19.17 9.48 8 189689 66 50415361
Joint effusion 19.13 9.48 98 189599 12923 50402504
Crystalluria 19.13 9.48 14 189683 375 50415052
Necrosis ischaemic 19.10 9.48 19 189678 780 50414647
Underdose 19.08 9.48 29 189668 20249 50395178
Arterial occlusive disease 19.04 9.48 50 189647 4758 50410669
Acute respiratory failure 19.02 9.48 178 189519 28604 50386823
Drug effective for unapproved indication 19.00 9.48 30 189667 1979 50413448
Capillary leak syndrome 18.96 9.48 29 189668 1861 50413566
Coronavirus infection 18.93 9.48 37 189660 2892 50412535
Product dispensing error 18.85 9.48 5 189692 8886 50406541
Meningomyelitis herpes 18.82 9.48 6 189691 20 50415407
Immunoglobulins decreased 18.76 9.48 21 189676 989 50414438
Weight increased 18.75 9.48 931 188766 200960 50214467
Myelocyte percentage increased 18.60 9.48 11 189686 203 50415224
Blindness cortical 18.59 9.48 14 189683 392 50415035
Asthenia 18.58 9.48 992 188705 318050 50097377
Focal segmental glomerulosclerosis 18.55 9.48 24 189673 1317 50414110
Hallucination 18.46 9.48 101 189596 46556 50368871
Klebsiella test positive 18.41 9.48 20 189677 911 50414516
Complications of transplant surgery 18.39 9.48 10 189687 156 50415271
Blood loss anaemia 18.38 9.48 4 189693 8135 50407292
Autoimmune hepatitis 18.35 9.48 66 189631 7453 50407974
Tuberculosis gastrointestinal 18.33 9.48 13 189684 331 50415096
Kaposi's sarcoma 18.28 9.48 10 189687 158 50415269
Nightmare 18.23 9.48 20 189677 16066 50399361
Hypoproteinaemia 18.23 9.48 28 189669 1803 50413624
Breast cancer metastatic 18.21 9.48 8 189689 10356 50405071
Renal tubular necrosis 18.18 9.48 81 189616 10087 50405340
Proteus infection 18.17 9.48 19 189678 828 50414599
Gastropleural fistula 18.01 9.48 7 189690 47 50415380
Pseudomonal sepsis 17.94 9.48 30 189667 2077 50413350
Thrombosis 17.88 9.48 129 189568 55704 50359723
Drug tolerance decreased 17.87 9.48 6 189691 9154 50406273
Gastrointestinal mucormycosis 17.83 9.48 11 189686 220 50415207
Gangrene 17.78 9.48 48 189649 4644 50410783
Hypertriglyceridaemia 17.71 9.48 53 189644 5438 50409989
Fungal infection 17.69 9.48 181 189516 29784 50385643
Tardive dyskinesia 17.66 9.48 3 189694 7276 50408151
Swollen tongue 17.65 9.48 52 189645 28578 50386849
Bacterial infection 17.65 9.48 113 189584 16168 50399259
Menstruation irregular 17.59 9.48 57 189640 6105 50409322
Malaise 17.59 9.48 1054 188643 334478 50080949
Hysterectomy 17.58 9.48 4 189693 7886 50407541
Urine oxalate increased 17.57 9.48 11 189686 226 50415201
Pyomyositis 17.45 9.48 13 189684 358 50415069
Blood brain barrier defect 17.42 9.48 8 189689 85 50415342
Adrenal atrophy 17.41 9.48 6 189691 27 50415400
Meningitis chemical 17.41 9.48 9 189688 126 50415301
Brain oedema 17.41 9.48 92 189605 12278 50403149
Enthesopathy 17.38 9.48 3 189694 7190 50408237
Pneumonia lipoid 17.35 9.48 9 189688 127 50415300
Premature baby 17.32 9.48 123 189574 18214 50397213
Sleep apnoea syndrome 17.28 9.48 40 189657 23828 50391599
Loss of consciousness 17.25 9.48 281 189416 104072 50311355
Sebaceous carcinoma 17.24 9.48 6 189691 28 50415399
Anal erythema 17.18 9.48 10 189687 179 50415248
JC polyomavirus test positive 17.17 9.48 21 189676 1088 50414339
Aphthous ulcer 17.16 9.48 82 189615 10515 50404912
Autoimmune thyroiditis 17.14 9.48 38 189659 3247 50412180
Eosinophil count increased 17.06 9.48 72 189625 8758 50406669
Liver abscess 17.06 9.48 33 189664 2560 50412867
Hepatic haemorrhage 16.96 9.48 14 189683 449 50414978
Dysmenorrhoea 16.94 9.48 38 189659 3272 50412155
Rhodococcus infection 16.94 9.48 8 189689 91 50415336
Dementia 16.94 9.48 21 189676 15976 50399451
Butterfly rash 16.91 9.48 22 189675 1214 50414213
Pneumonia bacterial 16.86 9.48 63 189634 7246 50408181
Chorioretinitis 16.81 9.48 14 189683 455 50414972
Mucous stools 16.78 9.48 35 189662 2867 50412560
Neuromyelitis optica spectrum disorder 16.78 9.48 18 189679 808 50414619
Abortion spontaneous 16.76 9.48 90 189607 41682 50373745
Drug-induced liver injury 16.73 9.48 170 189527 27925 50387502
Gamma-glutamyltransferase increased 16.58 9.48 177 189520 29446 50385981
Cytopenia 16.53 9.48 71 189626 8704 50406723
Sinusitis 16.48 9.48 500 189197 170058 50245369
Asymptomatic bacteriuria 16.44 9.48 11 189686 254 50415173
Allergy test positive 16.44 9.48 13 189684 392 50415035
Shock 16.40 9.48 133 189564 20517 50394910
Thyroid stimulating immunoglobulin 16.35 9.48 7 189690 62 50415365
Malacoplakia gastrointestinal 16.35 9.48 7 189690 62 50415365
Dural arteriovenous fistula 16.33 9.48 5 189692 14 50415413
Vaginal haemorrhage 16.32 9.48 43 189654 24508 50390919
Conjunctivitis 16.25 9.48 110 189587 16035 50399392
Infusion site pain 16.14 9.48 90 189607 12256 50403171
Viral myelitis 16.13 9.48 4 189693 3 50415424
Growth retardation 16.03 9.48 20 189677 1058 50414369
Magnesium deficiency 16.03 9.48 14 189683 486 50414941
Diverticulum 15.98 9.48 10 189687 10604 50404823
Haemodynamic instability 15.95 9.48 66 189631 7958 50407469
Hypersensitivity 15.92 9.48 652 189045 214509 50200918
Adult T-cell lymphoma/leukaemia 15.90 9.48 10 189687 207 50415220
Neoplasm progression 15.86 9.48 56 189641 29101 50386326
Bradycardia 15.83 9.48 334 189363 64092 50351335
Globulins decreased 15.78 9.48 10 189687 210 50415217
Complication associated with device 15.77 9.48 19 189678 14636 50400791
Infective pulmonary exacerbation of cystic fibrosis 15.75 9.48 5 189692 7904 50407523
Gastroduodenal ulcer 15.67 9.48 9 189688 157 50415270
Lymphocele 15.64 9.48 17 189680 775 50414652
Interleukin-2 receptor increased 15.61 9.48 7 189690 70 50415357
Haemorrhagic varicella syndrome 15.60 9.48 4 189693 4 50415423
Labelled drug-drug interaction medication error 15.60 9.48 10 189687 10467 50404960
Low birth weight baby 15.54 9.48 53 189644 5828 50409599
CD4 lymphocytes decreased 15.53 9.48 22 189675 1317 50414110
Dyskinesia 15.50 9.48 53 189644 27808 50387619
Lung abscess 15.44 9.48 24 189673 1562 50413865
Transient hypogammaglobulinaemia of infancy 15.34 9.48 6 189691 41 50415386
Pneumonia klebsiella 15.31 9.48 27 189670 1951 50413476
Jaundice neonatal 15.30 9.48 17 189680 794 50414633
Encephalitis brain stem 15.29 9.48 8 189689 115 50415312
Head injury 15.27 9.48 43 189654 23977 50391450
Allergy to plants 15.25 9.48 15 189682 607 50414820
Sinus bradycardia 15.23 9.48 93 189604 13090 50402337
Endocrine ophthalmopathy 15.20 9.48 12 189685 361 50415066
Pneumonia fungal 15.19 9.48 43 189654 4277 50411150
Aeromonas infection 15.19 9.48 7 189690 75 50415352
Lymphocyte count increased 15.18 9.48 34 189663 2925 50412502
Injection site extravasation 15.15 9.48 62 189635 7439 50407988
Heart transplant rejection 15.13 9.48 13 189684 441 50414986
Bilirubin urine present 15.11 9.48 7 189690 76 50415351
Meningitis cryptococcal 15.07 9.48 20 189677 1125 50414302
Arteriovenous fistula 15.06 9.48 10 189687 228 50415199
Anaemia 15.06 9.48 783 188914 251673 50163754
Bone erosion 15.02 9.48 13 189684 11674 50403753
Nasal septum disorder 14.99 9.48 8 189689 120 50415307
Thyroid stimulating immunoglobulin increased 14.95 9.48 7 189690 78 50415349
Thrombotic thrombocytopenic purpura 14.94 9.48 38 189659 3547 50411880
Fusarium infection 14.88 9.48 14 189683 536 50414891
Microsporidia infection 14.83 9.48 10 189687 234 50415193
Uterine perforation 14.80 9.48 3 189694 6412 50409015
Vein collapse 14.80 9.48 15 189682 630 50414797
pH urine increased 14.78 9.48 12 189685 376 50415051
Diabetic macroangiopathy 14.76 9.48 8 189689 124 50415303
Hyperoxaluria 14.76 9.48 8 189689 124 50415303
Histoplasmosis disseminated 14.73 9.48 21 189676 1265 50414162
Pneumonia cryptococcal 14.72 9.48 15 189682 634 50414793
Lipaemic index score 14.72 9.48 7 189690 81 50415346
Basal cell carcinoma 14.71 9.48 42 189655 23314 50392113
Bacterial vulvovaginitis 14.70 9.48 15 189682 635 50414792
Bursitis 14.68 9.48 137 189560 21998 50393429
Hepatitis acute 14.67 9.48 64 189633 7897 50407530
Nail bed inflammation 14.67 9.48 12 189685 380 50415047
Muscular weakness 14.66 9.48 463 189234 94550 50320877
Adjusted calcium decreased 14.65 9.48 8 189689 126 50415301
Gastrointestinal mucosa hyperaemia 14.63 9.48 9 189688 179 50415248
Pulmonary tuberculosis 14.51 9.48 42 189655 4231 50411196
Renal artery stenosis 14.49 9.48 24 189673 1648 50413779
Paraparesis 14.48 9.48 27 189670 2037 50413390
Blood lactate dehydrogenase increased 14.48 9.48 124 189573 19438 50395989
Product contamination 14.45 9.48 14 189683 556 50414871
Dystonia 14.45 9.48 14 189683 11912 50403515
Biliary anastomosis complication 14.42 9.48 5 189692 23 50415404
Relapsing-remitting multiple sclerosis 14.35 9.48 13 189684 474 50414953
Skin striae 14.34 9.48 19 189678 1067 50414360
Ependymoma 14.33 9.48 6 189691 50 50415377
Palmar erythema 14.31 9.48 23 189674 1540 50413887
Atrial fibrillation 14.28 9.48 282 189415 101463 50313964
Visceral leishmaniasis 14.28 9.48 13 189684 477 50414950
Meningitis listeria 14.28 9.48 13 189684 477 50414950
Enteritis 14.27 9.48 58 189639 6937 50408490
Tenosynovitis stenosans 14.26 9.48 28 189669 2196 50413231
Anaphylactic reaction 14.19 9.48 283 189414 53772 50361655
Urogenital disorder 14.12 9.48 6 189691 52 50415375
Anaphylactoid reaction 14.09 9.48 36 189661 3370 50412057
Capillaritis 14.07 9.48 7 189690 90 50415337
Excessive skin 14.06 9.48 8 189689 137 50415290
Trichodysplasia spinulosa 14.01 9.48 13 189684 489 50414938
Parathyroid hyperplasia 14.01 9.48 8 189689 138 50415289
Pneumocephalus 14.01 9.48 8 189689 138 50415289
Polymenorrhoea 14.00 9.48 19 189678 1092 50414335
Metastases to bone 13.98 9.48 29 189668 17966 50397461
Toxic epidermal necrolysis 13.96 9.48 130 189567 20862 50394565
Heart rate irregular 13.95 9.48 122 189575 19238 50396189
Infected varicose vein 13.93 9.48 5 189692 26 50415401
Polyglandular disorder 13.93 9.48 5 189692 26 50415401
Abnormal dreams 13.89 9.48 9 189688 9368 50406059
Fibromyalgia 13.89 9.48 105 189592 44873 50370554
T-lymphocyte count decreased 13.89 9.48 10 189687 261 50415166
Creatinine urine increased 13.87 9.48 9 189688 197 50415230
Interstitial lung disease 13.82 9.48 278 189419 52898 50362529
White blood cells urine 13.81 9.48 11 189686 335 50415092
Electrocardiogram QT prolonged 13.81 9.48 126 189571 51760 50363667
Delayed engraftment 13.80 9.48 7 189690 94 50415333
H3N2 influenza 13.77 9.48 3 189694 0 50415427
Ear neoplasm malignant 13.77 9.48 3 189694 0 50415427
Tubulointerstitial nephritis 13.77 9.48 101 189596 15110 50400317
Parainfluenzae virus infection 13.75 9.48 25 189672 1850 50413577
Mycoplasma test positive 13.74 9.48 6 189691 56 50415371
Hypocapnia 13.73 9.48 11 189686 338 50415089
Central obesity 13.68 9.48 18 189679 1004 50414423
Ovarian fibroma 13.67 9.48 7 189690 96 50415331
Glomerulonephritis chronic 13.66 9.48 8 189689 145 50415282
Passenger lymphocyte syndrome 13.65 9.48 6 189691 57 50415370
Low cardiac output syndrome 13.62 9.48 10 189687 269 50415158
Psychiatric decompensation 13.61 9.48 20 189677 1238 50414189
Transfusion 13.60 9.48 17 189680 12888 50402539
Foetal growth restriction 13.56 9.48 55 189642 6572 50408855
Chronic graft versus host disease in eye 13.54 9.48 7 189690 98 50415329
Synovial fluid analysis 13.52 9.48 23 189674 1615 50413812
Graft loss 13.51 9.48 11 189686 346 50415081
Product administration error 13.48 9.48 34 189663 19665 50395762
Thyroxine free decreased 13.45 9.48 13 189684 515 50414912
Enterocolitis viral 13.45 9.48 9 189688 208 50415219
Coagulation factor VIII level increased 13.39 9.48 4 189693 10 50415417
Renal impairment 13.38 9.48 375 189322 75286 50340141
Venous thrombosis 13.37 9.48 42 189655 4424 50411003
Haematemesis 13.31 9.48 56 189641 27669 50387758
Hepatic artery thrombosis 13.29 9.48 6 189691 61 50415366
Scleritis 13.24 9.48 34 189663 3193 50412234
Central venous pressure increased 13.18 9.48 7 189690 104 50415323
Oropharyngeal discomfort 13.17 9.48 38 189659 3820 50411607
Leukocytosis 13.15 9.48 136 189561 22443 50392984
Paraesthesia mucosal 13.12 9.48 4 189693 11 50415416
Cytomegalovirus duodenitis 13.12 9.48 4 189693 11 50415416
Complications of transplanted liver 13.11 9.48 11 189686 361 50415066
Coordination abnormal 13.09 9.48 81 189616 11453 50403974
Stenotrophomonas sepsis 13.06 9.48 5 189692 32 50415395
Epidural lipomatosis 13.06 9.48 7 189690 106 50415321
Eosinophilic granulomatosis with polyangiitis 13.01 9.48 25 189672 1930 50413497
Oral pain 13.01 9.48 49 189648 24984 50390443
Ureteral disorder 13.01 9.48 10 189687 289 50415138
Malacoplakia 13 9.48 7 189690 107 50415320
Type 1 diabetes mellitus 12.98 9.48 33 189664 3080 50412347
Respiratory arrest 12.97 9.48 63 189634 29946 50385481
Therapy partial responder 12.93 9.48 54 189643 6537 50408890
Poikiloderma 12.92 9.48 8 189689 161 50415266
B-lymphocyte count increased 12.89 9.48 7 189690 109 50415318
Granuloma skin 12.86 9.48 3 189694 5815 50409612
Lower respiratory tract infection bacterial 12.86 9.48 10 189687 294 50415133
Penicillium infection 12.83 9.48 7 189690 110 50415317
Chronic graft versus host disease oral 12.77 9.48 7 189690 111 50415316
Dry throat 12.77 9.48 48 189649 5536 50409891
Gastrointestinal scarring 12.76 9.48 9 189688 227 50415200
Allergy to chemicals 12.75 9.48 20 189677 1312 50414115
Tachypnoea 12.75 9.48 96 189601 14481 50400946
Kidney fibrosis 12.70 9.48 22 189675 1567 50413860
Laryngeal mass 12.69 9.48 5 189692 35 50415392
Hepatitis B 12.68 9.48 35 189662 3431 50411996
Monoparesis 12.67 9.48 21 189676 1443 50413984
Central nervous system lupus 12.66 9.48 10 189687 301 50415126
Exostosis 12.65 9.48 15 189682 11638 50403789
Herpes simplex encephalitis 12.63 9.48 10 189687 302 50415125
Lung transplant rejection 12.62 9.48 15 189682 754 50414673
Epstein-Barr viraemia 12.62 9.48 16 189681 860 50414567
Microangiopathy 12.52 9.48 16 189681 867 50414560
Injection site induration 12.52 9.48 8 189689 8389 50407038
Cytomegalovirus hepatitis 12.49 9.48 10 189687 307 50415120
Parkinsonism 12.43 9.48 9 189688 8838 50406589
Proctitis haemorrhagic 12.40 9.48 4 189693 14 50415413
Haemostasis 12.39 9.48 9 189688 238 50415189
Fracture 12.35 9.48 28 189669 16805 50398622
Obstructive airways disorder 12.35 9.48 25 189672 15627 50399800
Hypertensive encephalopathy 12.35 9.48 13 189684 571 50414856
Acute myocardial infarction 12.34 9.48 62 189635 29211 50386216
Oesophageal candidiasis 12.32 9.48 44 189653 4950 50410477
Rhinovirus infection 12.25 9.48 35 189662 3499 50411928
Cellulitis 12.25 9.48 189 189508 70609 50344818
Vaginal flatulence 12.23 9.48 9 189688 243 50415184
Glucose urine present 12.23 9.48 14 189683 676 50414751
Intestinal obstruction 12.23 9.48 54 189643 26329 50389098
Refractory anaemia with an excess of blasts 12.21 9.48 11 189686 398 50415029
Enterocolitis bacterial 12.18 9.48 8 189689 179 50415248
Myelitis transverse 12.14 9.48 17 189680 1007 50414420
Muscle hypertrophy 12.14 9.48 6 189691 76 50415351
Hepatic infarction 12.13 9.48 13 189684 583 50414844
Aspergillus test positive 12.11 9.48 10 189687 321 50415106
Hyperthermia 12.06 9.48 59 189638 7637 50407790
Fungal test positive 12.03 9.48 12 189685 494 50414933
Wound infection bacterial 12.03 9.48 12 189685 494 50414933
Hypokalaemia 12.01 9.48 245 189452 87747 50327680
Mental status changes 12.01 9.48 83 189614 36189 50379238
Dysaesthesia 12 9.48 36 189661 3699 50411728
Lung neoplasm malignant 11.99 9.48 25 189672 15459 50399968
Pharyngeal disorder 11.97 9.48 22 189675 1642 50413785
Organic brain syndrome 11.95 9.48 8 189689 185 50415242
Lung disorder 11.91 9.48 235 189462 44564 50370863
Intestine transplant rejection 11.91 9.48 5 189692 42 50415385
Extrapyramidal disorder 11.89 9.48 16 189681 11754 50403673
Chromoblastomycosis 11.79 9.48 4 189693 17 50415410
Meningitis staphylococcal 11.79 9.48 4 189693 17 50415410
Multiple fractures 11.78 9.48 5 189692 6606 50408821
Arteriosclerosis coronary artery 11.77 9.48 7 189690 7629 50407798
Pancreas transplant rejection 11.75 9.48 7 189690 131 50415296
Peripheral vascular disorder 11.73 9.48 3 189694 5464 50409963
Blood parathyroid hormone decreased 11.72 9.48 6 189691 7108 50408319
Tumour lysis syndrome 11.71 9.48 57 189640 7364 50408063
Blood catecholamines abnormal 11.70 9.48 3 189694 3 50415424
Otitis externa 11.70 9.48 21 189676 1539 50413888
Nephrolithiasis 11.68 9.48 79 189618 34614 50380813
Pre-existing condition improved 11.67 9.48 6 189691 7091 50408336
Papilloma viral infection 11.65 9.48 19 189678 1288 50414139
Acute lymphocytic leukaemia recurrent 11.63 9.48 24 189673 1951 50413476
Beta 2 microglobulin increased 11.61 9.48 7 189690 134 50415293
Cardiac disorder 11.60 9.48 104 189593 42875 50372552
Mucocutaneous leishmaniasis 11.60 9.48 10 189687 341 50415086
Hypoxia 11.59 9.48 262 189435 50861 50364566
Monocyte percentage decreased 11.55 9.48 8 189689 196 50415231
Tuberous sclerosis complex 11.55 9.48 6 189691 85 50415342
Viral myocarditis 11.53 9.48 9 189688 266 50415161
Vasculitis necrotising 11.53 9.48 12 189685 520 50414907
Amnesia 11.52 9.48 102 189595 42158 50373269
Foetal exposure during delivery 11.51 9.48 5 189692 46 50415381
Colitis microscopic 11.51 9.48 5 189692 6515 50408912
Acute disseminated encephalomyelitis 11.48 9.48 8 189689 198 50415229
Moraxella infection 11.48 9.48 10 189687 346 50415081
Thrombocytosis 11.47 9.48 43 189654 4953 50410474
Cytokine storm 11.39 9.48 9 189688 271 50415156
Eye infection toxoplasmal 11.39 9.48 9 189688 271 50415156
Multiple allergies 11.39 9.48 9 189688 8454 50406973
Occult blood 11.38 9.48 18 189679 1189 50414238
Hepatic failure 11.33 9.48 177 189520 32106 50383321
Serum ferritin increased 11.31 9.48 44 189653 5158 50410269
Neonatal pneumonia 11.27 9.48 4 189693 20 50415407
Oedema 11.26 9.48 190 189507 69991 50345436
Pneumonia pseudomonal 11.23 9.48 24 189673 1999 50413428
Candida test positive 11.23 9.48 15 189682 849 50414578
Hepatosplenomegaly 11.23 9.48 26 189671 2286 50413141
Vascular rupture 11.23 9.48 19 189678 1328 50414099
Viral pharyngitis 11.19 9.48 10 189687 358 50415069
Hepatitis cholestatic 11.14 9.48 49 189648 6068 50409359
Eosinophil count abnormal 11.13 9.48 11 189686 448 50414979
Carcinoma in situ 11.13 9.48 6 189691 92 50415335
Bulbar palsy 11.11 9.48 4 189693 21 50415406
Neuroblastoma recurrent 11.11 9.48 4 189693 21 50415406
Pneumonia acinetobacter 11.11 9.48 4 189693 21 50415406
Angiocentric lymphoma 11.09 9.48 12 189685 544 50414883
Ureteric obstruction 11.06 9.48 21 189676 1607 50413820
Infusion site discomfort 11.04 9.48 15 189682 863 50414564
Chest pain 11.04 9.48 546 189151 176336 50239091
Poor quality sleep 11.03 9.48 103 189594 16543 50398884
Hepatitis C 11.02 9.48 42 189655 4875 50410552
Normal newborn 11.00 9.48 52 189645 6639 50408788
Dysphagia 10.99 9.48 374 189323 77144 50338283
Irritability 10.99 9.48 62 189635 28364 50387063
Flatulence 10.98 9.48 65 189632 29393 50386034
Enteritis infectious 10.96 9.48 23 189674 1892 50413535
Pulse pressure increased 10.96 9.48 6 189691 95 50415332
Eschar 10.95 9.48 11 189686 457 50414970
Pneumothorax 10.94 9.48 90 189607 13944 50401483
Interleukin level increased 10.92 9.48 9 189688 288 50415139
B precursor type acute leukaemia 10.92 9.48 7 189690 150 50415277
Sputum discoloured 10.91 9.48 21 189676 13374 50402053
CD8 lymphocytes decreased 10.88 9.48 7 189690 151 50415276
Aspergilloma 10.88 9.48 7 189690 151 50415276
Toxic neuropathy 10.87 9.48 10 189687 372 50415055
Intestinal infarction 10.82 9.48 16 189681 996 50414431
Pseudomonal bacteraemia 10.82 9.48 18 189679 1241 50414186
Antibody test abnormal 10.81 9.48 11 189686 464 50414963
Corynebacterium sepsis 10.81 9.48 4 189693 23 50415404
Enterobacter pneumonia 10.81 9.48 4 189693 23 50415404
Withdrawal syndrome 10.81 9.48 32 189665 17558 50397869
Limb mass 10.78 9.48 28 189669 2647 50412780
Renal vein thrombosis 10.77 9.48 9 189688 294 50415133
Akathisia 10.76 9.48 9 189688 8220 50407207
Breast abscess 10.74 9.48 19 189678 1376 50414051
Secondary progressive multiple sclerosis 10.74 9.48 18 189679 1248 50414179
Metastases to central nervous system 10.74 9.48 16 189681 11266 50404161
Pneumoperitoneum 10.71 9.48 18 189679 1251 50414176
Live birth 10.71 9.48 29 189668 16379 50399048
Stem cell transplant 10.70 9.48 21 189676 1647 50413780
Calcium ionised increased 10.69 9.48 6 189691 100 50415327
Adenoviral haemorrhagic cystitis 10.68 9.48 7 189690 156 50415271
Device breakage 10.68 9.48 12 189685 9535 50405892
Hyperkalaemia 10.64 9.48 122 189575 47967 50367460
Infusion site extravasation 10.59 9.48 53 189644 6923 50408504
Bacillus bacteraemia 10.58 9.48 5 189692 57 50415370
Gastrointestinal hypermotility 10.56 9.48 7 189690 159 50415268
Angina unstable 10.54 9.48 6 189691 6700 50408727
Calcification of muscle 10.53 9.48 4 189693 25 50415402
Monocytopenia 10.50 9.48 5 189692 58 50415369
Osseous cryptococcosis 10.50 9.48 3 189694 6 50415421
Neurological decompensation 10.45 9.48 25 189672 2245 50413182
Paraesthesia ear 10.45 9.48 7 189690 162 50415265
Germ cell cancer 10.43 9.48 5 189692 59 50415368
Diffuse large B-cell lymphoma refractory 10.42 9.48 16 189681 1030 50414397
Bradyphrenia 10.42 9.48 5 189692 6147 50409280
Pulmonary arterial hypertension 10.41 9.48 40 189657 20279 50395148
Acute motor axonal neuropathy 10.40 9.48 4 189693 26 50415401
Salmonella test positive 10.40 9.48 4 189693 26 50415401
Glomerulonephritis proliferative 10.30 9.48 7 189690 166 50415261
Moyamoya disease 10.28 9.48 5 189692 61 50415366
Muscle strain 10.23 9.48 7 189690 7081 50408346
Microangiopathic haemolytic anaemia 10.23 9.48 11 189686 495 50414932
Cystitis viral 10.23 9.48 6 189691 109 50415318
Human herpes virus 8 test positive 10.19 9.48 3 189694 7 50415420
Acid base balance abnormal 10.18 9.48 8 189689 239 50415188
Drug level below therapeutic 10.14 9.48 34 189663 3706 50411721
Emphysematous pyelonephritis 10.12 9.48 7 189690 171 50415256
Microcytosis 10.12 9.48 7 189690 171 50415256
Atypical mycobacterial infection 10.12 9.48 14 189683 820 50414607
Back disorder 10.08 9.48 12 189685 9293 50406134
Hepatic steatosis 10.08 9.48 52 189645 24332 50391095
Pseudomembranous colitis 10.07 9.48 28 189669 2757 50412670
Large intestine perforation 10.05 9.48 55 189642 7439 50407988
Encephalitis Japanese B 10.03 9.48 4 189693 29 50415398
Skin erosion 10.02 9.48 25 189672 2306 50413121
Somnambulism 10.01 9.48 3 189694 4921 50410506
Hepatic vein occlusion 10.00 9.48 5 189692 65 50415362
Ophthalmoplegia 10.00 9.48 18 189679 1322 50414105
Escherichia bacteraemia 9.98 9.48 30 189667 3086 50412341
Chronic kidney disease 9.98 9.48 98 189599 39673 50375754
Tendon rupture 9.96 9.48 53 189644 7091 50408336
Hemiparesis 9.95 9.48 117 189580 19931 50395496
Histiocytic sarcoma 9.93 9.48 5 189692 66 50415361
Periventricular leukomalacia 9.93 9.48 5 189692 66 50415361
Cryptococcal meningoencephalitis 9.93 9.48 5 189692 66 50415361
Transaminases increased 9.93 9.48 153 189544 27671 50387756
Injection site discolouration 9.92 9.48 7 189690 6967 50408460
Listeria test positive 9.90 9.48 3 189694 8 50415419
Waxy flexibility 9.90 9.48 6 189691 116 50415311
Hot flush 9.90 9.48 226 189471 43943 50371484
Idiopathic pneumonia syndrome 9.87 9.48 9 189688 331 50415096
Sensory loss 9.85 9.48 56 189641 7682 50407745
Gastrointestinal oedema 9.84 9.48 16 189681 1082 50414345
Larynx irritation 9.81 9.48 6 189691 118 50415309
Administration site oedema 9.80 9.48 4 189693 31 50415396
Cytomegalovirus gastritis 9.78 9.48 7 189690 181 50415246
Disseminated cytomegaloviral infection 9.78 9.48 7 189690 181 50415246
Haemorrhagic cyst 9.78 9.48 7 189690 181 50415246
Therapeutic response decreased 9.77 9.48 239 189458 46992 50368435
Agranulocytosis 9.76 9.48 123 189574 21298 50394129
Respiratory gas exchange disorder 9.73 9.48 9 189688 337 50415090
Hepatic enzyme abnormal 9.73 9.48 40 189657 4809 50410618
Blood pressure systolic decreased 9.73 9.48 45 189652 5694 50409733
CSF oligoclonal band present 9.72 9.48 6 189691 120 50415307
Autoimmune hypothyroidism 9.72 9.48 6 189691 120 50415307
Hyperuricaemia 9.70 9.48 39 189658 4641 50410786
Laryngospasm 9.69 9.48 27 189670 2661 50412766
Visual tracking test abnormal 9.65 9.48 3 189694 9 50415418
Myocardiac abscess 9.65 9.48 3 189694 9 50415418
Cerebral vasoconstriction 9.64 9.48 15 189682 977 50414450
Mycobacterium kansasii infection 9.64 9.48 6 189691 122 50415305
Thrombocytopenic purpura 9.63 9.48 17 189680 1229 50414198
Generalised oedema 9.62 9.48 86 189611 13645 50401782
Immunosuppression 9.62 9.48 54 189643 7372 50408055
Glomerulonephritis membranous 9.60 9.48 11 189686 532 50414895
Oropharyngeal plaque 9.58 9.48 8 189689 261 50415166
Blindness 9.58 9.48 103 189594 17166 50398261
Acne 9.57 9.48 114 189583 19481 50395946
Pulseless electrical activity 9.56 9.48 7 189690 6834 50408593
Respiratory tract oedema 9.52 9.48 10 189687 438 50414989
Disorientation 9.52 9.48 86 189611 35398 50380029
Locked-in syndrome 9.51 9.48 9 189688 347 50415080
Hemianopia 9.51 9.48 14 189683 868 50414559
Skin test positive 9.50 9.48 12 189685 643 50414784

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Cytomegalovirus infection 800.49 10.39 721 127564 22494 29423748
Off label use 767.05 10.39 2944 125341 297856 29148386
Product use in unapproved indication 491.09 10.39 1131 127154 85744 29360498
Death 396.44 10.39 545 127740 341539 29104703
Infusion related reaction 369.41 10.39 674 127611 43212 29403030
Drug ineffective for unapproved indication 346.11 10.39 365 127920 13849 29432393
Transplant rejection 317.08 10.39 286 127999 8926 29437316
Completed suicide 315.52 10.39 19 128266 90227 29356015
Graft versus host disease 287.17 10.39 276 128009 9352 29436890
Kidney transplant rejection 286.56 10.39 240 128045 6765 29439477
Multiple organ dysfunction syndrome 279.47 10.39 749 127536 62367 29383875
Drug abuse 275.69 10.39 18 128267 79865 29366377
Pneumocystis jirovecii pneumonia 268.04 10.39 347 127938 16432 29429810
Aspergillus infection 267.05 10.39 277 128008 10304 29435938
Bronchopulmonary aspergillosis 263.89 10.39 296 127989 12048 29434194
Mucormycosis 241.06 10.39 191 128094 4967 29441275
Cytomegalovirus viraemia 239.02 10.39 207 128078 6113 29440129
Epstein-Barr virus infection 234.44 10.39 209 128076 6420 29439822
Posterior reversible encephalopathy syndrome 226.54 10.39 235 128050 8741 29437501
Post transplant lymphoproliferative disorder 220.15 10.39 186 128099 5307 29440935
Product dose omission issue 219.90 10.39 72 128213 96311 29349931
Toxicity to various agents 219.80 10.39 258 128027 173403 29272839
Fall 212.91 10.39 274 128011 176904 29269338
Drug ineffective 201.89 10.39 2431 125854 360739 29085503
Respiratory failure 195.49 10.39 887 127398 96244 29349998
Strongyloidiasis 192.90 10.39 122 128163 2190 29444052
Complications of transplanted kidney 192.51 10.39 150 128135 3804 29442438
Thrombotic microangiopathy 180.14 10.39 205 128080 8476 29437766
Acute graft versus host disease in skin 174.83 10.39 152 128133 4512 29441730
Cytomegalovirus test positive 173.50 10.39 133 128152 3290 29442952
Fatigue 173.44 10.39 747 127538 316074 29130168
Septic shock 166.61 10.39 623 127662 61937 29384305
Dizziness 165.23 10.39 361 127924 189323 29256919
Syncope 163.66 10.39 74 128211 81297 29364945
Adenovirus infection 160.82 10.39 142 128143 4305 29441937
Polyomavirus-associated nephropathy 159.22 10.39 126 128159 3270 29442972
Graft versus host disease in gastrointestinal tract 157.32 10.39 123 128162 3135 29443107
Acute graft versus host disease 147.90 10.39 153 128132 5671 29440571
Nausea 138.75 10.39 715 127570 288540 29157702
Blood pressure fluctuation 137.19 10.39 281 128004 19613 29426629
Blood pressure diastolic abnormal 135.66 10.39 102 128183 2449 29443793
Myocardial infarction 133.94 10.39 169 128116 110127 29336115
BK virus infection 129.27 10.39 129 128156 4578 29441664
Disseminated intravascular coagulation 128.19 10.39 274 128011 19706 29426536
Oxygen saturation decreased 127.59 10.39 457 127828 44480 29401762
Cytomegalovirus infection reactivation 126.83 10.39 110 128175 3254 29442988
Pneumonia cytomegaloviral 126.79 10.39 100 128185 2582 29443660
Cardiac failure congestive 123.58 10.39 91 128194 76490 29369752
Intentional overdose 121.02 10.39 13 128272 38515 29407727
Cystitis haemorrhagic 120.79 10.39 126 128159 4716 29441526
Asthenia 120.28 10.39 503 127782 214747 29231495
Haemophagocytic lymphohistiocytosis 118.47 10.39 184 128101 10320 29435922
Graft versus host disease in skin 118.41 10.39 106 128179 3273 29442969
Pneumatosis intestinalis 116.21 10.39 102 128183 3067 29443175
Steroid diabetes 113.33 10.39 78 128207 1623 29444619
Candida infection 112.08 10.39 221 128064 15004 29431238
Lymphocyte count decreased 109.78 10.39 252 128033 19019 29427223
Hospitalisation 109.03 10.39 32 128253 45956 29400286
Acute graft versus host disease in liver 105.17 10.39 68 128217 1270 29444972
Cerebrovascular accident 100.66 10.39 111 128174 76800 29369442
Enterococcal infection 97.70 10.39 148 128137 8120 29438122
Dehydration 96.80 10.39 222 128063 114526 29331716
Pseudomonas infection 95.43 10.39 170 128115 10682 29435560
Nocardiosis 94.46 10.39 92 128193 3168 29443074
Intentional product use issue 94.39 10.39 400 127885 42098 29404144
Parvovirus B19 infection 94.31 10.39 51 128234 673 29445569
Acute graft versus host disease in intestine 93.24 10.39 79 128206 2262 29443980
Overdose 93.06 10.39 126 128159 79693 29366549
Blood pressure systolic abnormal 92.45 10.39 76 128209 2085 29444157
Coronary artery disease 90.67 10.39 39 128246 44151 29402091
Chronic graft versus host disease 90.19 10.39 99 128186 3930 29442312
Hypoglycaemia 85.29 10.39 52 128233 48294 29397948
Human herpesvirus 6 infection 84.93 10.39 68 128217 1795 29444447
Acute respiratory distress syndrome 84.60 10.39 255 128030 22680 29423562
Delayed graft function 82.91 10.39 68 128217 1859 29444383
Constipation 82.34 10.39 239 128046 113921 29332321
Klebsiella infection 76.35 10.39 124 128161 7225 29439017
Depression 75.67 10.39 160 128125 84987 29361255
Bacterial sepsis 74.66 10.39 97 128188 4606 29441636
Blood pressure systolic increased 74.52 10.39 200 128085 16645 29429597
Drug resistance 73.42 10.39 233 128052 21307 29424935
Suicide attempt 73.40 10.39 28 128257 34082 29412160
Drug interaction 73.38 10.39 528 127757 196857 29249385
Pyrexia 72.84 10.39 1695 126590 285927 29160315
Focal segmental glomerulosclerosis 72.01 10.39 61 128224 1746 29444496
Central nervous system fungal infection 70.95 10.39 33 128252 308 29445934
Progressive multifocal leukoencephalopathy 70.85 10.39 132 128153 8587 29437655
Disseminated mucormycosis 70.49 10.39 33 128252 313 29445929
Vomiting 70.38 10.39 586 127699 211674 29234568
Cytomegalovirus colitis 70.27 10.39 69 128216 2400 29443842
Anaphylactic shock 69.01 10.39 168 128117 13168 29433074
Wrong technique in product usage process 68.97 10.39 25 128260 31403 29414839
Systemic mycosis 68.43 10.39 52 128233 1269 29444973
Lymphopenia 67.40 10.39 168 128117 13365 29432877
Pneumomediastinum 67.37 10.39 58 128227 1698 29444544
Cytomegalovirus enteritis 66.13 10.39 34 128251 402 29445840
Liver transplant rejection 65.39 10.39 60 128225 1914 29444328
Blood pressure increased 65.30 10.39 545 127740 73258 29372984
Nephropathy toxic 63.86 10.39 143 128142 10613 29435629
Epstein-Barr virus associated lymphoproliferative disorder 63.84 10.39 56 128229 1682 29444560
Feeling abnormal 63.38 10.39 86 128199 54359 29391883
Fungal infection 63.09 10.39 165 128120 13520 29432722
Mycobacterium chelonae infection 60.74 10.39 36 128249 572 29445670
Cryptococcosis 60.17 10.39 57 128228 1895 29444347
Pneumocystis jirovecii infection 60.01 10.39 50 128235 1398 29444844
Injection site pain 59.92 10.39 33 128252 32413 29413829
Pulmonary mucormycosis 58.49 10.39 34 128251 520 29445722
International normalised ratio increased 58.07 10.39 64 128221 44308 29401934
Renal tubular necrosis 57.41 10.39 164 128121 14151 29432091
Immunosuppressant drug level increased 57.30 10.39 86 128199 4679 29441563
Infection reactivation 56.77 10.39 43 128242 1044 29445198
Confusional state 56.70 10.39 324 127961 127553 29318689
Hyperglycaemia 55.85 10.39 295 127990 33992 29412250
Diarrhoea 54.80 10.39 1066 127219 331632 29114610
Cushingoid 54.73 10.39 60 128225 2378 29443864
Enterobacter infection 54.48 10.39 55 128230 1979 29444263
Renal tubular atrophy 53.97 10.39 41 128244 1000 29445242
Chronic allograft nephropathy 53.46 10.39 42 128243 1078 29445164
Lymphocyte percentage decreased 53.04 10.39 54 128231 1963 29444279
Cardiac disorder 53.02 10.39 50 128235 37213 29409029
Condition aggravated 52.92 10.39 910 127375 145385 29300857
Decreased appetite 52.88 10.39 391 127894 144951 29301291
Staphylococcal sepsis 52.81 10.39 118 128167 8744 29437498
Red blood cells urine positive 51.85 10.39 49 128236 1624 29444618
Orthostatic hypotension 51.38 10.39 17 128268 22612 29423630
Transplant dysfunction 51.20 10.39 56 128229 2214 29444028
Myalgia 51.14 10.39 158 128127 73861 29372381
Chorioretinopathy 50.77 10.39 45 128240 1371 29444871
Therapy non-responder 50.37 10.39 266 128019 30645 29415597
Heart rate decreased 50.35 10.39 228 128057 24684 29421558
Cytomegalovirus chorioretinitis 50.18 10.39 66 128219 3172 29443070
Herpes simplex 50.11 10.39 82 128203 4808 29441434
Leukopenia 50.06 10.39 410 127875 54793 29391449
Serotonin syndrome 49.97 10.39 8 128277 17504 29428738
Sepsis 49.97 10.39 883 127402 141799 29304443
Intentional product misuse 49.91 10.39 46 128239 34615 29411627
Product prescribing error 49.56 10.39 9 128276 17967 29428275
Oedema peripheral 49.40 10.39 256 128029 103301 29342941
Renal transplant failure 49.39 10.39 38 128247 945 29445297
Cytomegalovirus enterocolitis 48.86 10.39 35 128250 778 29445464
Pulmonary alveolar haemorrhage 48.63 10.39 94 128191 6286 29439956
Neutrophil percentage increased 47.41 10.39 48 128237 1733 29444509
Lethargy 47.22 10.39 56 128229 37524 29408718
Aggression 46.79 10.39 51 128234 35490 29410752
Pneumonia fungal 46.36 10.39 87 128198 5690 29440552
Disease recurrence 46.12 10.39 163 128122 15751 29430491
Suicidal ideation 45.50 10.39 50 128235 34666 29411576
Rhabdomyolysis 45.50 10.39 125 128160 60683 29385559
Peripheral swelling 44.78 10.39 135 128150 63604 29382638
Amoebic colitis 44.15 10.39 16 128269 72 29446170
Graft versus host disease in liver 43.98 10.39 37 128248 1049 29445193
Necrotising retinitis 43.73 10.39 32 128253 736 29445506
Kidney fibrosis 43.58 10.39 49 128236 1998 29444244
Gastroenteritis norovirus 43.48 10.39 41 128244 1355 29444887
Oliguria 43.39 10.39 98 128187 7314 29438928
Hypoalbuminaemia 43.23 10.39 120 128165 10185 29436057
Muscle spasms 42.81 10.39 142 128143 64940 29381302
Intentional self-injury 42.39 10.39 3 128282 12458 29433784
Rebound effect 42.19 10.39 48 128237 1983 29444259
Intestinal ischaemia 42.02 10.39 91 128194 6601 29439641
Pneumonia pseudomonal 41.93 10.39 61 128224 3226 29443016
Acinetobacter infection 41.76 10.39 35 128250 987 29445255
Dural arteriovenous fistula 41.50 10.39 13 128272 33 29446209
Urine analysis abnormal 41.22 10.39 45 128240 1775 29444467
Transplant failure 40.88 10.39 56 128229 2800 29443442
Skin necrosis 40.87 10.39 76 128209 4936 29441306
Diabetes mellitus 40.61 10.39 304 127981 39527 29406715
Urine abnormality 40.32 10.39 43 128242 1651 29444591
Viraemia 40.24 10.39 35 128250 1039 29445203
Dyspnoea 40.19 10.39 1095 127190 325637 29120605
Cytomegalovirus oesophagitis 39.91 10.39 24 128261 392 29445850
Porphyria acute 39.72 10.39 19 128266 190 29446052
Balance disorder 39.26 10.39 60 128225 36110 29410132
Myopathy 38.73 10.39 117 128168 10416 29435826
Accidental overdose 38.59 10.39 14 128271 17579 29428663
Phaeohyphomycosis 38.18 10.39 30 128255 770 29445472
Plasma cell myeloma 37.99 10.39 64 128221 37051 29409191
Mycobacterium abscessus infection 37.98 10.39 24 128261 430 29445812
Contusion 37.32 10.39 48 128237 31047 29415195
Pneumonia acinetobacter 37.29 10.39 14 128271 71 29446171
Transient ischaemic attack 37.05 10.39 28 128257 23242 29423000
Diffuse alveolar damage 36.99 10.39 45 128240 1998 29444244
Epstein-Barr viraemia 36.91 10.39 32 128253 946 29445296
Incision site pain 36.80 10.39 42 128243 1741 29444501
Erectile dysfunction 36.76 10.39 16 128269 17993 29428249
Back pain 36.30 10.39 277 128008 102007 29344235
Large intestine perforation 36.29 10.39 91 128194 7265 29438977
Treatment noncompliance 36.27 10.39 31 128254 24196 29422046
Immunosuppressant drug level decreased 36.05 10.39 34 128251 1124 29445118
Intensive care unit acquired weakness 35.88 10.39 31 128254 912 29445330
Diffuse large B-cell lymphoma 35.65 10.39 82 128203 6194 29440048
Disseminated cryptococcosis 35.55 10.39 34 128251 1144 29445098
Psoriasis 35.42 10.39 53 128232 32174 29414068
Blood pressure diastolic increased 35.34 10.39 60 128225 3626 29442616
Pyelonephritis acute 35.32 10.39 40 128245 1644 29444598
Granulomatosis with polyangiitis 34.91 10.39 30 128255 876 29445366
Chest pain 34.85 10.39 314 127971 111659 29334583
JC virus infection 34.70 10.39 42 128243 1855 29444387
Pneumonia cryptococcal 34.69 10.39 28 128257 748 29445494
Full blood count decreased 34.61 10.39 13 128272 15979 29430263
Necrosis ischaemic 34.49 10.39 18 128267 220 29446022
Varicella zoster virus infection 34.48 10.39 37 128248 1431 29444811
Pneumothorax 34.29 10.39 148 128137 15694 29430548
Somnolence 34.02 10.39 253 128032 93702 29352540
Serum sickness 33.80 10.39 40 128245 1725 29444517
Psoriatic arthropathy 33.41 10.39 11 128274 14680 29431562
American trypanosomiasis 33.39 10.39 18 128267 236 29446006
Ureteric stenosis 33.28 10.39 32 128253 1084 29445158
Sedation 33.17 10.39 17 128268 17388 29428854
Haemolytic anaemia 33.11 10.39 103 128182 9316 29436926
Cutaneous mucormycosis 32.95 10.39 14 128271 103 29446139
Loss of personal independence in daily activities 32.94 10.39 37 128248 25403 29420839
Intra-abdominal haemorrhage 32.93 10.39 43 128242 2052 29444190
Perinephric abscess 32.85 10.39 11 128274 37 29446205
Product quality issue 32.64 10.39 14 128271 15881 29430361
Human herpesvirus 8 infection 32.54 10.39 28 128257 819 29445423
Pain in extremity 32.51 10.39 314 127971 110119 29336123
Gait disturbance 32.38 10.39 186 128099 73163 29373079
Penicillium infection 32.28 10.39 13 128272 82 29446160
Protein urine present 31.99 10.39 66 128219 4628 29441614
Crystal urine present 31.76 10.39 21 128264 408 29445834
Neuropathy peripheral 31.42 10.39 180 128105 70847 29375395
Drug effective for unapproved indication 31.27 10.39 35 128250 1420 29444822
Malignant neoplasm progression 31.17 10.39 190 128095 73669 29372573
Staphylococcal infection 30.28 10.39 224 128061 29016 29417226
Febrile bone marrow aplasia 30.24 10.39 85 128200 7266 29438976
Hypertension 30.20 10.39 690 127595 115924 29330318
Injection site swelling 30.02 10.39 3 128282 9414 29436828
COVID-19 pneumonia 29.74 10.39 100 128185 9422 29436820
Hypogammaglobulinaemia 29.06 10.39 73 128212 5834 29440408
Osteomyelitis fungal 28.70 10.39 16 128269 225 29446017
Pulmonary nocardiosis 28.67 10.39 22 128263 545 29445697
Extrapyramidal disorder 28.64 10.39 6 128279 10825 29435417
Fusarium infection 28.63 10.39 28 128257 969 29445273
Blood creatine phosphokinase increased 28.60 10.39 86 128199 40558 29405684
Depressed mood 28.57 10.39 18 128267 16430 29429812
Parvovirus infection 28.53 10.39 20 128265 429 29445813
Anxiety 28.51 10.39 235 128050 85130 29361112
Pain 28.49 10.39 548 127737 170884 29275358
Red cell distribution width increased 28.41 10.39 63 128222 4644 29441598
Bronchopleural fistula 28.17 10.39 20 128265 438 29445804
Glomerulosclerosis 28.07 10.39 24 128261 696 29445546
Memory impairment 28 10.39 74 128211 36396 29409846
Proteinuria 27.83 10.39 139 128146 15665 29430577
Acute myocardial infarction 27.68 10.39 112 128173 48326 29397916
Escherichia infection 27.61 10.39 78 128207 6686 29439556
Neuroleptic malignant syndrome 27.60 10.39 18 128267 16130 29430112
Adverse event 27.59 10.39 16 128269 15275 29430967
Hyperkalaemia 27.46 10.39 155 128130 61237 29385005
Dyspnoea exertional 27.29 10.39 75 128210 36415 29409827
Opportunistic infection 27.29 10.39 33 128252 1456 29444786
Renal impairment 27.24 10.39 500 127785 80833 29365409
Abdominal discomfort 27.23 10.39 111 128174 47792 29398450
Atrial fibrillation 27.18 10.39 310 127975 105336 29340906
Hallucination 27.08 10.39 101 128184 44611 29401631
Prostate cancer 27.07 10.39 43 128242 25484 29420758
Symptom masked 26.96 10.39 21 128264 532 29445710
Monocyte percentage increased 26.89 10.39 26 128259 887 29445355
Corynebacterium infection 26.89 10.39 19 128266 413 29445829
Thrombocytopenia 26.77 10.39 770 127515 134053 29312189
Angiosarcoma 26.73 10.39 16 128269 259 29445983
Pemphigus 26.66 10.39 29 128256 1139 29445103
Product substitution issue 26.60 10.39 4 128281 9168 29437074
Haemodynamic instability 26.30 10.39 86 128199 7987 29438255
Viral haemorrhagic cystitis 26.25 10.39 26 128259 914 29445328
Anaphylactic reaction 26.18 10.39 207 128078 27366 29418876
Gastrointestinal candidiasis 26.10 10.39 13 128272 143 29446099
Osteonecrosis 26.03 10.39 122 128163 13397 29432845
Respiratory arrest 26.02 10.39 45 128240 25788 29420454
Blood beta-D-glucan increased 26.01 10.39 18 128267 378 29445864
Obliterative bronchiolitis 25.99 10.39 28 128257 1088 29445154
Pneumoretroperitoneum 25.97 10.39 10 128275 55 29446187
Red blood cell schistocytes present 25.94 10.39 15 128270 227 29446015
Peritonitis 25.83 10.39 130 128155 14694 29431548
Pseudomonal sepsis 25.75 10.39 46 128239 2896 29443346
Fungaemia 25.71 10.39 39 128246 2142 29444100
Rhinocerebral mucormycosis 25.44 10.39 15 128270 236 29446006
Lymphoproliferative disorder 25.38 10.39 42 128243 2485 29443757
Malaise 25.36 10.39 514 127771 159088 29287154
Hypophagia 25.27 10.39 32 128253 20840 29425402
Cryptococcal meningoencephalitis 25.26 10.39 12 128273 118 29446124
Complications of transplant surgery 24.95 10.39 19 128266 465 29445777
Enterococcal bacteraemia 24.93 10.39 32 128253 1501 29444741
Bacteraemia 24.91 10.39 138 128147 16185 29430057
Engraftment syndrome 24.81 10.39 24 128261 819 29445423
Insomnia 24.61 10.39 256 128029 88505 29357737
Disseminated strongyloidiasis 24.59 10.39 11 128274 93 29446149
Drug withdrawal syndrome 24.57 10.39 25 128260 17959 29428283
Vasculitis 24.53 10.39 83 128202 7845 29438397
Aplastic anaemia 24.46 10.39 80 128205 7430 29438812
Systemic inflammatory response syndrome 24.45 10.39 69 128216 5912 29440330
Reticulocytosis 24.27 10.39 15 128270 258 29445984
Leukocytosis 24.23 10.39 166 128119 20976 29425266
Sleep disorder 24.09 10.39 43 128242 24343 29421899
Erythema 24.01 10.39 461 127824 75145 29371097
Low birth weight baby 23.91 10.39 73 128212 6535 29439707
Haemolytic uraemic syndrome 23.91 10.39 36 128249 1964 29444278
Specific gravity urine increased 23.86 10.39 12 128273 135 29446107
Glomerulonephritis 23.83 10.39 33 128252 1667 29444575
Systemic candida 23.73 10.39 43 128242 2737 29443505
Therapy cessation 23.54 10.39 17 128268 14445 29431797
Pulmonary haemorrhage 23.54 10.39 91 128194 9179 29437063
Apoptosis 23.53 10.39 14 128271 224 29446018
Quadriplegia 23.33 10.39 31 128254 1505 29444737
Cholelithiasis 23.26 10.39 28 128257 18644 29427598
Cold type haemolytic anaemia 23.26 10.39 10 128275 76 29446166
Headache 23.20 10.39 576 127709 173431 29272811
Road traffic accident 23.18 10.39 20 128265 15541 29430701
Therapeutic response decreased 23.18 10.39 185 128100 24526 29421716
Pneumonia bacterial 23.15 10.39 91 128194 9252 29436990
Respiratory tract infection fungal 23.14 10.39 21 128264 660 29445582
Graft complication 23.12 10.39 16 128269 336 29445906
Bronchopneumopathy 23.08 10.39 17 128268 395 29445847
Antineutrophil cytoplasmic antibody positive 23.07 10.39 20 128265 591 29445651
Chills 23.06 10.39 436 127849 70864 29375378
Viral cardiomyopathy 23.02 10.39 8 128277 31 29446211
Tremor 22.96 10.39 206 128079 73332 29372910
Fungal skin infection 22.95 10.39 39 128246 2359 29443883
Laboratory test abnormal 22.95 10.39 27 128258 18158 29428084
Respiratory disorder 22.94 10.39 139 128146 16844 29429398
Renal graft infection 22.90 10.39 14 128271 236 29446006
Pulmonary embolism 22.77 10.39 217 128068 76317 29369925
Cytomegalovirus hepatitis 22.61 10.39 15 128270 293 29445949
Renal tubular injury 22.50 10.39 21 128264 685 29445557
Candida sepsis 22.42 10.39 26 128259 1097 29445145
Respiratory distress 22.23 10.39 225 128060 31881 29414361
Osteoporosis 22.08 10.39 99 128186 10670 29435572
Sideroblastic anaemia 22.02 10.39 13 128272 205 29446037
Lung abscess 22.01 10.39 38 128247 2328 29443914
Fluid retention 21.99 10.39 43 128242 23517 29422725
Nightmare 21.98 10.39 11 128274 11406 29434836
COVID-19 21.95 10.39 246 128039 35768 29410474
Injection site erythema 21.95 10.39 17 128268 13939 29432303
Adenoviral hepatitis 21.69 10.39 13 128272 211 29446031
Amoebiasis 21.68 10.39 9 128276 62 29446180
Toxic epidermal necrolysis 21.68 10.39 144 128141 18009 29428233
Full blood count abnormal 21.52 10.39 20 128265 14993 29431249
Skin striae 21.45 10.39 17 128268 442 29445800
Hepatic failure 21.42 10.39 220 128065 31292 29414950
Encephalitis fungal 21.32 10.39 12 128273 172 29446070
Adenoviral haemorrhagic cystitis 21.17 10.39 16 128269 387 29445855
Wound evisceration 21.17 10.39 10 128275 97 29446145
Foetal growth restriction 21.17 10.39 49 128236 3717 29442525
Graft loss 21.03 10.39 22 128263 826 29445416
Hepatocellular injury 21.01 10.39 161 128124 21082 29425160
Scopulariopsis infection 20.99 10.39 10 128275 99 29446143
Atypical mycobacterial pneumonia 20.97 10.39 11 128274 136 29446106
Human polyomavirus infection 20.96 10.39 20 128265 671 29445571
Enterococcal sepsis 20.82 10.39 29 128256 1473 29444769
Hypocalcaemia 20.81 10.39 36 128249 20629 29425613
Palmar-plantar erythrodysaesthesia syndrome 20.76 10.39 20 128265 14739 29431503
Herpes simplex viraemia 20.54 10.39 9 128276 72 29446170
Lupus nephritis 20.52 10.39 13 128272 234 29446008
Herpes zoster 20.52 10.39 210 128075 29842 29416400
Injection site bruising 20.46 10.39 4 128281 7576 29438666
Haematemesis 20.44 10.39 48 128237 24578 29421664
Feeling hot 20.43 10.39 126 128159 15362 29430880
Pneumonia klebsiella 20.21 10.39 39 128246 2605 29443637
Poisoning 20.20 10.39 9 128276 9984 29436258
Thrombosis 20.17 10.39 107 128178 42938 29403304
Dyskinesia 20.15 10.39 35 128250 20026 29426216
Neck pain 20.14 10.39 39 128246 21408 29424834
Abnormal dreams 20.11 10.39 3 128282 6917 29439325
Neuromyelitis optica spectrum disorder 20.08 10.39 10 128275 110 29446132
Mean cell haemoglobin increased 20.03 10.39 25 128260 1140 29445102
Abdominal pain upper 19.86 10.39 169 128116 60824 29385418
Multiple sclerosis relapse 19.80 10.39 100 128185 11319 29434923
Adverse drug reaction 19.79 10.39 47 128238 23973 29422269
Dysgeusia 19.79 10.39 43 128242 22631 29423611
Dry skin 19.69 10.39 45 128240 23262 29422980
Neurological decompensation 19.66 10.39 37 128248 2425 29443817
Drug intolerance 19.61 10.39 126 128159 48253 29397989
Gastric disorder 19.60 10.39 11 128274 10693 29435549
Bursitis infective 19.59 10.39 17 128268 503 29445739
Injection site haemorrhage 19.57 10.39 6 128279 8380 29437862
Blood pressure diastolic decreased 19.55 10.39 71 128214 6951 29439291
Torulopsis infection 19.51 10.39 6 128279 14 29446228
Osmotic demyelination syndrome 19.44 10.39 19 128266 657 29445585
Cystitis escherichia 19.41 10.39 11 128274 160 29446082
Megacolon 19.34 10.39 29 128256 1576 29444666
Pathogen resistance 19.26 10.39 78 128207 8038 29438204
Device issue 19.20 10.39 5 128280 7775 29438467
Splenic embolism 19.11 10.39 11 128274 165 29446077
Periumbilical abscess 19.05 10.39 8 128277 57 29446185
Unevaluable event 19.02 10.39 66 128219 29785 29416457
Central nervous system infection 18.98 10.39 17 128268 525 29445717
Gonococcal infection 18.89 10.39 7 128278 34 29446208
Accelerated idioventricular rhythm 18.73 10.39 9 128276 91 29446151
Diarrhoea haemorrhagic 18.62 10.39 62 128223 5812 29440430
C-reactive protein abnormal 18.62 10.39 3 128282 6533 29439709
Blood glucose decreased 18.61 10.39 15 128270 12054 29434188
Meningitis fungal 18.56 10.39 9 128276 93 29446149
Engraft failure 18.54 10.39 15 128270 402 29445840
Cerebral aspergillosis 18.53 10.39 26 128259 1330 29444912
Unresponsive to stimuli 18.52 10.39 52 128233 25074 29421168
Dry mouth 18.45 10.39 42 128243 21742 29424500
Peritoneal candidiasis 18.43 10.39 6 128279 18 29446224
Injection site reaction 18.41 10.39 13 128272 11175 29435067
Cerebral fungal infection 18.38 10.39 12 128273 228 29446014
Pneumoperitoneum 18.36 10.39 28 128257 1545 29444697
Fungal sepsis 18.32 10.39 20 128265 789 29445453
White blood cells urine positive 18.30 10.39 24 128261 1150 29445092
Klebsiella sepsis 18.29 10.39 29 128256 1655 29444587
Hepatic artery thrombosis 18.29 10.39 12 128273 230 29446012
Neutrophil count increased 18.25 10.39 118 128167 14624 29431618
Pneumonia escherichia 18.13 10.39 14 128271 350 29445892
Cytokine release syndrome 18.12 10.39 108 128177 13011 29433231
Subdural haematoma 18.04 10.39 32 128253 18161 29428081
Epstein-Barr virus associated lymphoma 18.00 10.39 17 128268 563 29445679
Rheumatoid arthritis 17.98 10.39 216 128069 31936 29414306
Electrocardiogram QT prolonged 17.97 10.39 88 128197 36049 29410193
Bordetella infection 17.91 10.39 9 128276 101 29446141
Myelocyte present 17.78 10.39 4 128281 0 29446242
Incorrect dose administered 17.77 10.39 78 128207 32906 29413336
Thyrotoxic periodic paralysis 17.64 10.39 8 128277 70 29446172
Hepatitis A 17.60 10.39 15 128270 433 29445809
Disseminated trichosporonosis 17.54 10.39 7 128278 43 29446199
Abdominal abscess 17.51 10.39 46 128239 3778 29442464
Haemolysis 17.43 10.39 68 128217 6888 29439354
Cutaneous malacoplakia 17.40 10.39 7 128278 44 29446198
Angiocentric lymphoma 17.34 10.39 12 128273 252 29445990
Contraindicated product administered 17.34 10.39 33 128252 18233 29428009
Autoimmune haemolytic anaemia 17.33 10.39 46 128239 3802 29442440
Meningitis cryptococcal 17.32 10.39 32 128253 2068 29444174
Akathisia 17.29 10.39 4 128281 6738 29439504
Lymphangitis 17.26 10.39 16 128269 517 29445725
Pneumonia adenoviral 17.26 10.39 10 128275 152 29446090
Flushing 17.20 10.39 197 128088 28795 29417447
Bacterial test 17.14 10.39 10 128275 154 29446088
Hypersomnia 17.04 10.39 13 128272 10741 29435501
General physical health deterioration 16.99 10.39 329 127956 102528 29343714
Monocytopenia 16.99 10.39 8 128277 77 29446165
Mean cell haemoglobin concentration decreased 16.96 10.39 22 128263 1043 29445199
Immunosuppression 16.94 10.39 56 128229 5230 29441012
Urine leukocyte esterase positive 16.82 10.39 14 128271 391 29445851
Mucosal ulceration 16.80 10.39 20 128265 868 29445374
Hyponatraemia 16.78 10.39 200 128085 67433 29378809
Agitation 16.77 10.39 142 128143 51162 29395080
Diffuse mesangial sclerosis 16.74 10.39 6 128279 26 29446216
Dysphagia 16.64 10.39 155 128130 54771 29391471
Cerebral venous thrombosis 16.63 10.39 17 128268 621 29445621
Intravascular haemolysis 16.61 10.39 14 128271 398 29445844
Urticaria 16.57 10.39 331 127954 54329 29391913
Lung transplant rejection 16.57 10.39 18 128267 706 29445536
Microsporidia infection 16.52 10.39 16 128269 547 29445695
Diaphragmatic injury 16.50 10.39 9 128276 121 29446121
Dystonia 16.48 10.39 11 128274 9738 29436504
Gastritis fungal 16.38 10.39 8 128277 84 29446158
Glucose-6-phosphate dehydrogenase deficiency 16.37 10.39 9 128276 123 29446119
Meningitis bacterial 16.29 10.39 22 128263 1085 29445157
Listeriosis 16.26 10.39 20 128265 898 29445344
Urinary retention 16.25 10.39 77 128208 31821 29414421
Retinal detachment 16.25 10.39 51 128234 4635 29441607
Diabetic ketoacidosis 16.18 10.39 28 128257 16045 29430197
Total lung capacity abnormal 16.18 10.39 9 128276 126 29446116
Angina pectoris 16.16 10.39 64 128221 27786 29418456
Multi-organ disorder 16.07 10.39 22 128263 1099 29445143
Salivary hypersecretion 16.07 10.39 6 128279 7403 29438839
Pneumonia influenzal 15.98 10.39 24 128261 1306 29444936
Disseminated blastomycosis 15.98 10.39 8 128277 89 29446153
Lymphocele 15.96 10.39 24 128261 1308 29444934
Bradycardia 15.93 10.39 195 128090 65434 29380808
Cutaneous nocardiosis 15.87 10.39 9 128276 131 29446111
Immune thrombocytopenia 15.84 10.39 72 128213 7805 29438437
Prescribed overdose 15.78 10.39 9 128276 8674 29437568
Hypoxia 15.75 10.39 291 127994 47088 29399154
Arterial spasm 15.75 10.39 8 128277 92 29446150
Urobilinogen urine increased 15.74 10.39 13 128272 359 29445883
Eosinophil percentage decreased 15.68 10.39 8 128277 93 29446149
Pulmonary hypertension 15.66 10.39 36 128249 18572 29427670
Underdose 15.65 10.39 17 128268 11852 29434390
Cytomegalovirus gastrointestinal infection 15.64 10.39 10 128275 183 29446059
Heart transplant rejection 15.62 10.39 22 128263 1129 29445113
Faeces discoloured 15.62 10.39 21 128264 13330 29432912
Vision blurred 15.59 10.39 106 128179 40070 29406172
Paranoia 15.58 10.39 12 128273 9865 29436377
Blood sodium decreased 15.54 10.39 25 128260 14742 29431500
B-lymphocyte count decreased 15.53 10.39 15 128270 511 29445731
IgA nephropathy 15.53 10.39 21 128264 1037 29445205
Anaemia 15.51 10.39 713 127572 200238 29246004
Blood immunoglobulin G decreased 15.50 10.39 22 128263 1137 29445105
Urinoma 15.50 10.39 10 128275 186 29446056
Irritability 15.49 10.39 47 128238 22105 29424137
Immune reconstitution inflammatory syndrome 15.46 10.39 71 128214 7731 29438511
Infective pulmonary exacerbation of cystic fibrosis 15.41 10.39 4 128281 6232 29440010
Labelled drug-drug interaction medication error 15.40 10.39 18 128267 12141 29434101
Surgery 15.39 10.39 17 128268 11762 29434480
Hepatitis cholestatic 15.38 10.39 65 128220 6828 29439414
Exposure during pregnancy 15.36 10.39 9 128276 8545 29437697
Pseudomonal bacteraemia 15.35 10.39 20 128265 952 29445290
Haptoglobin decreased 15.29 10.39 15 128270 521 29445721
Cardiac failure 15.20 10.39 247 128038 79040 29367202
Intestinal ulcer 15.19 10.39 18 128267 777 29445465
Disorientation 15.18 10.39 71 128214 29444 29416798
Angioedema 15.13 10.39 79 128206 31836 29414406
Post procedural urine leak 15.13 10.39 9 128276 144 29446098
IVth nerve paralysis 15.10 10.39 8 128277 101 29446141
Wolff-Parkinson-White syndrome 15.09 10.39 10 128275 195 29446047
Pleural mass 15.08 10.39 7 128278 65 29446177
Acne fulminans 15.07 10.39 9 128276 145 29446097
Intestine transplant rejection 15.01 10.39 6 128279 37 29446205
Hip fracture 15.01 10.39 14 128271 10478 29435764
Encephalopathy 15.00 10.39 203 128082 30840 29415402
Morganella infection 14.99 10.39 14 128271 457 29445785
Bilirubin urine present 14.97 10.39 9 128276 147 29446095
Epstein-Barr virus infection reactivation 14.92 10.39 15 128270 537 29445705
Nervous system neoplasm 14.91 10.39 9 128276 148 29446094
Bifidobacterium infection 14.89 10.39 5 128280 17 29446225
Pseudopolyposis 14.88 10.39 6 128279 38 29446204
Treatment failure 14.87 10.39 234 128051 36705 29409537
Herpes zoster meningoencephalitis 14.77 10.39 11 128274 260 29445982
Sudden death 14.74 10.39 24 128261 14086 29432156
Bacterial test positive 14.74 10.39 36 128249 2827 29443415
Trichophytosis 14.67 10.39 11 128274 263 29445979
Urinary fistula 14.63 10.39 8 128277 108 29446134
Uraemic encephalopathy 14.63 10.39 11 128274 264 29445978
Dyspepsia 14.61 10.39 74 128211 30051 29416191
Disturbance in attention 14.59 10.39 46 128239 21378 29424864
Seronegative arthritis 14.58 10.39 19 128266 905 29445337
Cytomegalovirus gastritis 14.53 10.39 10 128275 208 29446034
Mobility decreased 14.48 10.39 60 128225 25720 29420522
Therapeutic product effect decreased 14.48 10.39 72 128213 29379 29416863
Injection site mass 14.47 10.39 3 128282 5452 29440790
Blood lactate dehydrogenase increased 14.46 10.39 137 128148 19072 29427170
Pleuropericarditis 14.45 10.39 10 128275 210 29446032
Bacterial infection 14.44 10.39 101 128184 12847 29433395
Product storage error 14.44 10.39 5 128280 6465 29439777
Campylobacter gastroenteritis 14.44 10.39 17 128268 729 29445513
Encephalitis cytomegalovirus 14.42 10.39 14 128271 480 29445762
Abdominal compartment syndrome 14.41 10.39 18 128267 821 29445421
Liver function test 14.37 10.39 6 128279 42 29446200
Drug level below therapeutic 14.36 10.39 46 128239 4225 29442017
Dermatophytosis 14.33 10.39 10 128275 213 29446029
Heart rate increased 14.31 10.39 243 128042 38695 29407547
Withdrawal syndrome 14.21 10.39 16 128269 10976 29435266
Cytomegalovirus nephritis 14.20 10.39 8 128277 115 29446127
Secondary immunodeficiency 14.18 10.39 12 128273 343 29445899
Steroid withdrawal syndrome 14.17 10.39 10 128275 217 29446025
Fungal endocarditis 14.15 10.39 11 128274 278 29445964
Epstein-Barr virus test positive 14.14 10.39 14 128271 492 29445750
Familial periodic paralysis 14.13 10.39 7 128278 76 29446166
Respiratory depression 14.13 10.39 23 128262 13500 29432742
Haematopoietic stem cell mobilisation 14.11 10.39 9 128276 164 29446078
Haemoglobinuria 14.11 10.39 15 128270 574 29445668
Aspiration 14.08 10.39 14 128271 10166 29436076
Hepatitis 14.07 10.39 145 128140 20638 29425604
Gastrointestinal perforation 14.06 10.39 40 128245 3443 29442799
Kaposi's sarcoma 14.03 10.39 18 128267 844 29445398
Splenic necrosis 14.02 10.39 6 128279 45 29446197
Acinetobacter test positive 14.02 10.39 8 128277 118 29446124
Chimerism 14.01 10.39 10 128275 221 29446021
Injection site pruritus 13.98 10.39 4 128281 5845 29440397
Stenotrophomonas infection 13.95 10.39 26 128259 1691 29444551
Ageusia 13.92 10.39 11 128274 8927 29437315
Cystitis viral 13.91 10.39 14 128271 502 29445740
Aplasia 13.88 10.39 44 128241 4019 29442223
Encephalitis 13.86 10.39 60 128225 6370 29439872
Substance-induced psychotic disorder 13.85 10.39 23 128262 1365 29444877
Type I hypersensitivity 13.83 10.39 20 128265 1052 29445190
Disseminated varicella zoster vaccine virus infection 13.80 10.39 6 128279 47 29446195
Bundle branch block left 13.80 10.39 3 128282 5274 29440968
Eye luxation 13.76 10.39 4 128281 7 29446235
Scedosporium infection 13.74 10.39 17 128268 768 29445474
Tardive dyskinesia 13.72 10.39 3 128282 5255 29440987
Pulmonary fibrosis 13.72 10.39 115 128170 15467 29430775
Abscess sterile 13.71 10.39 5 128280 23 29446219
Leishmaniasis 13.69 10.39 11 128274 292 29445950
Muscle twitching 13.64 10.39 9 128276 8017 29438225
Skin discolouration 13.63 10.39 29 128256 15380 29430862
Exophthalmos 13.55 10.39 14 128271 518 29445724
Chronic obstructive pulmonary disease 13.54 10.39 113 128172 40842 29405400
Hypocomplementaemia 13.54 10.39 5 128280 24 29446218
Interstitial lung disease 13.54 10.39 337 127948 57381 29388861
Marrow hyperplasia 13.54 10.39 19 128266 972 29445270
Bilirubin conjugated increased 13.52 10.39 36 128249 2981 29443261
Device related sepsis 13.52 10.39 32 128253 2463 29443779
Tricuspid valve incompetence 13.49 10.39 10 128275 8384 29437858
Prostatic specific antigen increased 13.48 10.39 21 128264 12543 29433699
Middle insomnia 13.47 10.39 4 128281 5704 29440538
Product administration error 13.45 10.39 26 128259 14284 29431958
Spermatozoa progressive motility decreased 13.45 10.39 8 128277 128 29446114
Eschar 13.43 10.39 15 128270 607 29445635
Optic nerve compression 13.42 10.39 4 128281 8 29446234
Deep vein thrombosis 13.38 10.39 172 128113 57227 29389015
Chronic papillomatous dermatitis 13.38 10.39 6 128279 51 29446191
Arteritis coronary 13.38 10.39 6 128279 51 29446191
Herpes simplex hepatitis 13.38 10.39 7 128278 86 29446156
Tongue fungal infection 13.37 10.39 5 128280 25 29446217
Necrosis 13.29 10.39 50 128235 4980 29441262
Peliosis hepatis 13.28 10.39 6 128279 52 29446190
Arterial rupture 13.24 10.39 13 128272 452 29445790
Blood immunoglobulin M decreased 13.23 10.39 12 128273 377 29445865
Bacterial pyelonephritis 13.23 10.39 10 128275 242 29446000
Impaired work ability 13.22 10.39 4 128281 5636 29440606
Paraplegia 13.19 10.39 32 128253 2502 29443740
Organising pneumonia 13.18 10.39 50 128235 4998 29441244
Hepatitis B 13.18 10.39 53 128232 5444 29440798
Specific gravity urine decreased 13.17 10.39 7 128278 89 29446153
Epistaxis 13.17 10.39 152 128133 51552 29394690
Pneumonia necrotising 13.16 10.39 14 128271 536 29445706
Perforation 13.13 10.39 9 128276 186 29446056
Trichosporon infection 13.08 10.39 15 128270 625 29445617
Graft infection 13.07 10.39 12 128273 383 29445859
Arthritis fungal 13.04 10.39 7 128278 91 29446151
Tachypnoea 13.01 10.39 111 128174 15004 29431238
Venoocclusive liver disease 13.01 10.39 62 128223 6855 29439387
Enterococcus test positive 13.00 10.39 16 128269 719 29445523
Nephrolithiasis 13.00 10.39 61 128224 25273 29420969
Rectal haemorrhage 12.99 10.39 92 128193 34457 29411785
Glomerulonephropathy 12.96 10.39 9 128276 190 29446052
Muscle rigidity 12.95 10.39 13 128272 9398 29436844
Gynaecomastia 12.94 10.39 10 128275 8207 29438035
Haemoperitoneum 12.91 10.39 24 128261 1558 29444684
Donor specific antibody present 12.90 10.39 7 128278 93 29446149
Cerebral venous sinus thrombosis 12.89 10.39 12 128273 390 29445852
Kidney rupture 12.88 10.39 9 128276 192 29446050
Hypoacusis 12.88 10.39 27 128258 14396 29431846
Nephrotic syndrome 12.84 10.39 58 128227 6270 29439972
Presyncope 12.84 10.39 32 128253 16057 29430185
Endocarditis 12.83 10.39 54 128231 5662 29440580
Head injury 12.82 10.39 32 128253 16049 29430193
Escherichia sepsis 12.80 10.39 42 128243 3907 29442335
Shock haemorrhagic 12.79 10.39 78 128207 9473 29436769
Urine ketone body present 12.72 10.39 19 128266 1029 29445213
Viral load abnormal 12.72 10.39 6 128279 58 29446184
Back disorder 12.69 10.39 5 128280 5968 29440274
Biopsy lymph gland 12.63 10.39 6 128279 59 29446183
Capnocytophaga infection 12.63 10.39 6 128279 59 29446183
Smooth muscle cell neoplasm 12.63 10.39 8 128277 144 29446098
Blood potassium increased 12.61 10.39 28 128257 14623 29431619
Malacoplakia gastrointestinal 12.58 10.39 7 128278 98 29446144
Stupor 12.56 10.39 33 128252 2711 29443531
Herpes simplex meningoencephalitis 12.54 10.39 4 128281 11 29446231
Polychondritis 12.53 10.39 8 128277 146 29446096
Haemodialysis 12.52 10.39 80 128205 9874 29436368
Emotional disorder 12.50 10.39 3 128282 4928 29441314
Type 2 diabetes mellitus 12.49 10.39 25 128260 13556 29432686
Abdominal infection 12.48 10.39 22 128263 1370 29444872
Arrhythmia 12.46 10.39 82 128203 31231 29415011
Immune-mediated lung disease 12.44 10.39 16 128269 752 29445490
Meningoencephalitis herpetic 12.42 10.39 16 128269 753 29445489
Capillaritis 12.40 10.39 7 128278 101 29446141
Retinal pigment epitheliopathy 12.37 10.39 9 128276 205 29446037
Infective tenosynovitis 12.37 10.39 6 128279 62 29446180
Gastrointestinal ulcer 12.31 10.39 24 128261 1615 29444627
Renal necrosis 12.30 10.39 8 128277 151 29446091
Adenomatous polyposis coli 12.30 10.39 8 128277 151 29446091
Abnormal behaviour 12.27 10.39 55 128230 23072 29423170
Pericarditis fungal 12.25 10.39 8 128277 152 29446090
Post procedural bile leak 12.23 10.39 10 128275 272 29445970
Nephritis 12.23 10.39 28 128257 2108 29444134
Removal of renal transplant 12.23 10.39 5 128280 33 29446209
Band neutrophil percentage increased 12.22 10.39 7 128278 104 29446138
Loss of consciousness 12.19 10.39 237 128048 73819 29372423
Retinal scar 12.17 10.39 10 128275 274 29445968
Nocturia 12.15 10.39 11 128274 8351 29437891
Fungal peritonitis 12.14 10.39 15 128270 677 29445565
Sexual dysfunction 12.13 10.39 5 128280 5809 29440433
Erythema infectiosum 12.12 10.39 8 128277 155 29446087
Aspergillus test positive 12.11 10.39 12 128273 422 29445820
Hepatic cirrhosis 12.11 10.39 28 128257 14416 29431826
Acute myeloid leukaemia recurrent 12.10 10.39 25 128260 1755 29444487
Arteriosclerosis coronary artery 12.08 10.39 17 128268 10588 29435654
Atrioventricular block first degree 12.06 10.39 4 128281 5315 29440927
Lymphocytic infiltration 12.06 10.39 14 128271 591 29445651
Inadequate aseptic technique in use of product 12.05 10.39 4 128281 13 29446229
Lipoma 12.05 10.39 22 128263 1409 29444833
Cardiac arrest 12.02 10.39 281 128004 85310 29360932
Hyperthermia 11.99 10.39 76 128209 9354 29436888
Necrotising oesophagitis 11.99 10.39 13 128272 509 29445733
Disseminated varicella zoster virus infection 11.98 10.39 8 128277 158 29446084
Atypical mycobacterial infection 11.98 10.39 15 128270 686 29445556
Hepatitis E 11.95 10.39 24 128261 1650 29444592
Cavernous sinus thrombosis 11.94 10.39 8 128277 159 29446083
Oral herpes 11.93 10.39 45 128240 4487 29441755
Citrobacter infection 11.93 10.39 12 128273 430 29445812
Cataract subcapsular 11.86 10.39 11 128274 356 29445886
Phaeochromocytoma 11.85 10.39 8 128277 161 29446081
Herpes simplex colitis 11.82 10.39 4 128281 14 29446228
Growth hormone deficiency 11.79 10.39 9 128276 221 29446021
C-reactive protein increased 11.78 10.39 263 128022 44000 29402242
Poikiloderma 11.77 10.39 8 128277 163 29446079
Herpes zoster cutaneous disseminated 11.77 10.39 8 128277 163 29446079
Tuberculosis 11.77 10.39 62 128223 7134 29439108
Limbic encephalitis 11.73 10.39 11 128274 361 29445881
Transaminases increased 11.70 10.39 150 128135 22512 29423730
Drug dependence 11.68 10.39 49 128236 20932 29425310
Computerised tomogram thorax abnormal 11.66 10.39 14 128271 613 29445629
Pulmonary thrombosis 11.66 10.39 7 128278 6558 29439684
Granuloma 11.65 10.39 30 128255 2434 29443808
Aplasia pure red cell 11.65 10.39 51 128234 5440 29440802
Palatal ulcer 11.63 10.39 5 128280 38 29446204
Acute endocarditis 11.61 10.39 4 128281 15 29446227
Dehiscence 11.59 10.39 6 128279 72 29446170
Anuria 11.58 10.39 76 128209 9465 29436777
Coombs direct test positive 11.55 10.39 10 128275 295 29445947
Restlessness 11.55 10.39 53 128232 22092 29424150
Pharyngeal paraesthesia 11.53 10.39 12 128273 448 29445794
Medication error 11.52 10.39 50 128235 21161 29425081
Body height below normal 11.52 10.39 9 128276 229 29446013
Amoebic dysentery 11.52 10.39 5 128280 39 29446203
Gastric haemorrhage 11.52 10.39 14 128271 9283 29436959
Hypercapnia 11.52 10.39 39 128246 3687 29442555
Colitis 11.48 10.39 195 128090 31053 29415189
Therapeutic product effect prolonged 11.42 10.39 9 128276 232 29446010
Carotid artery insufficiency 11.41 10.39 4 128281 16 29446226
Radiotherapy to brain 11.41 10.39 5 128280 40 29446202
Autoimmune hepatitis 11.40 10.39 38 128247 3564 29442678
Fungal disease carrier 11.39 10.39 9 128276 233 29446009
Hepatic artery occlusion 11.38 10.39 6 128279 75 29446167
pH urine increased 11.38 10.39 6 128279 75 29446167
Folliculitis 11.34 10.39 40 128245 3860 29442382
Multiple-drug resistance 11.34 10.39 40 128245 3860 29442382
Hepatic function abnormal 11.32 10.39 236 128049 39023 29407219
Cardiomegaly 11.31 10.39 27 128258 13749 29432493
Polychromasia 11.30 10.39 7 128278 121 29446121
Throat irritation 11.29 10.39 71 128214 8714 29437528
Band neutrophil count increased 11.29 10.39 9 128276 236 29446006
Neonatal multi-organ failure 11.27 10.39 3 128282 3 29446239
Macrophage activation 11.27 10.39 3 128282 3 29446239
Idiopathic pneumonia syndrome 11.26 10.39 9 128276 237 29446005
Mycobacterium kansasii infection 11.26 10.39 9 128276 237 29446005
Acute disseminated encephalomyelitis 11.24 10.39 6 128279 77 29446165
Palpitations 11.22 10.39 89 128196 32515 29413727
Brain herniation 11.21 10.39 38 128247 3595 29442647
Superinfection 11.21 10.39 26 128259 1975 29444267
Rib fracture 11.20 10.39 24 128261 12694 29433548
Mood swings 11.19 10.39 9 128276 7242 29439000
Glucose tolerance impaired 11.19 10.39 32 128253 2762 29443480
Gastrointestinal wall thickening 11.18 10.39 19 128266 1149 29445093
Encephalitis brain stem 11.17 10.39 6 128279 78 29446164
Pancreas transplant rejection 11.16 10.39 8 128277 178 29446064
Retching 11.13 10.39 6 128279 5967 29440275
Lung neoplasm malignant 11.12 10.39 29 128256 14328 29431914
Aortic pseudoaneurysm 11.10 10.39 5 128280 43 29446199
Inflammatory marker increased 11.00 10.39 38 128247 3629 29442613
ADAMTS13 activity decreased 10.98 10.39 6 128279 81 29446161
Urinary sediment present 10.97 10.39 8 128277 183 29446059
Vitamin B1 decreased 10.94 10.39 9 128276 247 29445995
Tumour lysis syndrome 10.94 10.39 100 128185 13784 29432458
Hilar lymphadenopathy 10.93 10.39 16 128269 851 29445391
Panic attack 10.90 10.39 12 128273 8314 29437928
Device leakage 10.88 10.39 3 128282 4492 29441750
Inhibin B 10.87 10.39 4 128281 19 29446223
Glycosylated haemoglobin increased 10.85 10.39 15 128270 9411 29436831
Glomerulonephritis minimal lesion 10.85 10.39 11 128274 398 29445844
Rash papulosquamous 10.81 10.39 5 128280 46 29446196
Dysarthria 10.81 10.39 84 128201 30827 29415415
Self-induced vomiting 10.81 10.39 3 128282 4 29446238
Coordination abnormal 10.77 10.39 9 128276 7105 29439137
Gallbladder rupture 10.76 10.39 12 128273 485 29445757
Gastroenteritis rotavirus 10.75 10.39 8 128277 189 29446053
Splenic infection fungal 10.72 10.39 6 128279 85 29446157
Flatulence 10.72 10.39 40 128245 17669 29428573
Infective aortitis 10.70 10.39 4 128281 20 29446222
Pulmonary cavitation 10.68 10.39 15 128270 768 29445474
Eczema 10.65 10.39 28 128257 13798 29432444
Body temperature decreased 10.64 10.39 81 128204 10583 29435659
Severe acute respiratory syndrome 10.63 10.39 5 128280 48 29446194
Pancreatitis 10.62 10.39 97 128188 34417 29411825
Knee arthroplasty 10.59 10.39 6 128279 5803 29440439
Lower gastrointestinal haemorrhage 10.57 10.39 12 128273 8201 29438041
Mean platelet volume decreased 10.54 10.39 11 128274 412 29445830
Epididymitis 10.51 10.39 27 128258 2188 29444054
Blindness cortical 10.49 10.39 10 128275 335 29445907
Eosinophil percentage increased 10.47 10.39 12 128273 500 29445742
Inappropriate schedule of product administration 10.46 10.39 133 128152 44339 29401903
Pulmonary fistula 10.45 10.39 5 128280 50 29446192
Complication of device removal 10.45 10.39 5 128280 50 29446192
Disseminated tuberculosis 10.45 10.39 25 128260 1937 29444305
Acute kidney injury 10.41 10.39 1000 127285 264267 29181975
Hypertensive encephalopathy 10.39 10.39 10 128275 339 29445903

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Cytomegalovirus infection 1343.05 9.91 1202 287313 35997 64174220
Off label use 1098.89 9.91 5649 282866 627157 63583060
Product use in unapproved indication 931.41 9.91 2281 286234 174337 64035880
Completed suicide 870.18 9.91 30 288485 224384 63985833
Infusion related reaction 815.39 9.91 2075 286440 162392 64047825
Death 552.33 9.91 816 287699 481889 63728328
Toxicity to various agents 551.75 9.91 489 288026 363024 63847193
Drug ineffective for unapproved indication 534.89 9.91 678 287837 30455 64179762
Transplant rejection 517.47 9.91 505 288010 16896 64193321
Blood pressure fluctuation 465.65 9.91 834 287681 51037 64159180
Aspergillus infection 460.44 9.91 461 288054 15918 64194299
Drug abuse 458.68 9.91 35 288480 132339 64077878
Bronchopulmonary aspergillosis 448.39 9.91 488 288027 18597 64191620
Product dose omission issue 430.81 9.91 166 288349 194581 64015636
Posterior reversible encephalopathy syndrome 426.69 9.91 520 287995 22426 64187791
Cytomegalovirus viraemia 410.72 9.91 360 288155 10468 64199749
Lymphocyte count decreased 406.52 9.91 686 287829 40013 64170204
Multiple organ dysfunction syndrome 402.60 9.91 1180 287335 100233 64109984
Fall 396.43 9.91 792 287723 416034 63794183
Kidney transplant rejection 392.81 9.91 332 288183 9179 64201038
Mucormycosis 383.41 9.91 294 288221 7047 64203170
Pneumocystis jirovecii pneumonia 374.21 9.91 536 287979 27098 64183119
Blood pressure diastolic abnormal 369.67 9.91 354 288161 11563 64198654
Oxygen saturation decreased 364.90 9.91 1182 287333 105994 64104223
Urine abnormality 324.81 9.91 267 288248 7095 64203122
Thrombotic microangiopathy 323.65 9.91 386 288129 16269 64193948
Drug ineffective 317.11 9.91 5392 283123 834855 63375362
Blood pressure systolic abnormal 305.86 9.91 294 288221 9648 64200569
Epstein-Barr virus infection 301.54 9.91 324 288191 12164 64198053
Polyomavirus-associated nephropathy 300.66 9.91 216 288299 4672 64205545
Respiratory failure 291.35 9.91 1459 287056 159724 64050493
Blood pressure increased 288.35 9.91 1528 286987 171024 64039193
Graft versus host disease 288.15 9.91 332 288183 13481 64196736
Complications of transplanted kidney 284.57 9.91 218 288297 5217 64205000
Post transplant lymphoproliferative disorder 276.32 9.91 273 288242 9271 64200946
Intentional overdose 274.90 9.91 38 288477 89906 64120311
Haemophagocytic lymphohistiocytosis 262.92 9.91 358 288157 17251 64192966
Graft versus host disease in gastrointestinal tract 252.76 9.91 206 288309 5406 64204811
BK virus infection 248.70 9.91 230 288285 7182 64203035
Red blood cells urine positive 233.10 9.91 179 288336 4299 64205918
Cytomegalovirus test positive 227.86 9.91 187 288328 4957 64205260
Steroid diabetes 224.19 9.91 143 288372 2523 64207694
Cytomegalovirus infection reactivation 223.58 9.91 194 288321 5562 64204655
Overdose 219.20 9.91 234 288281 159332 64050885
Blood pressure systolic increased 214.18 9.91 594 287921 48859 64161358
Urine leukocyte esterase positive 210.73 9.91 151 288364 3252 64206965
Strongyloidiasis 209.67 9.91 145 288370 2945 64207272
Adenovirus infection 209.06 9.91 207 288308 7048 64203169
Injection site pain 207.74 9.91 120 288395 111288 64098929
Heart rate decreased 205.38 9.91 627 287888 54440 64155777
Urinary sediment present 203.35 9.91 126 288389 2108 64208109
Cardiac failure congestive 203.35 9.91 171 288344 130409 64079808
White blood cells urine positive 201.77 9.91 178 288337 5220 64204997
Enterococcal infection 201.13 9.91 278 288237 13588 64196629
Nocardiosis 200.14 9.91 168 288347 4599 64205618
Pseudomonas infection 199.58 9.91 317 288198 17566 64192651
Septic shock 199.36 9.91 967 287548 104470 64105747
Myocardial infarction 196.26 9.91 273 288242 165548 64044669
Confusional state 195.59 9.91 562 287953 260582 63949635
Syncope 188.08 9.91 258 288257 157377 64052840
Crystal urine present 186.32 9.91 113 288402 1816 64208401
Lymphopenia 186.26 9.91 377 288138 25280 64184937
Glossodynia 184.86 9.91 33 288482 64663 64145554
Throat irritation 181.07 9.91 431 288084 32280 64177937
Synovitis 178.75 9.91 111 288404 98979 64111238
Graft versus host disease in skin 175.69 9.91 164 288351 5183 64205034
Dehydration 175.42 9.91 449 288066 216314 63993903
Dizziness 173.61 9.91 1169 287346 428994 63781223
Lymphocyte percentage decreased 173.17 9.91 153 288362 4496 64205721
Pneumonia cytomegaloviral 172.10 9.91 148 288367 4191 64206026
Klebsiella infection 171.61 9.91 252 288263 13029 64197188
Pneumatosis intestinalis 171.08 9.91 160 288355 5069 64205148
Delayed graft function 170.52 9.91 127 288388 2909 64207308
Neutrophil percentage increased 169.00 9.91 148 288367 4297 64205920
Hospitalisation 168.01 9.91 63 288452 75144 64135073
Wrong technique in product usage process 167.50 9.91 42 288473 64932 64145285
Acute graft versus host disease in skin 162.24 9.91 176 288339 6679 64203538
Nausea 160.50 9.91 2513 286002 783287 63426930
Disseminated intravascular coagulation 156.66 9.91 405 288110 31943 64178274
Vomiting 155.94 9.91 1645 286870 549472 63660745
Diarrhoea 155.47 9.91 2288 286227 720416 63489801
Urine analysis abnormal 154.43 9.91 158 288357 5598 64204619
Alopecia 153.55 9.91 319 288196 165371 64044846
Progressive multifocal leukoencephalopathy 153.22 9.91 285 288230 17947 64192270
Cerebrovascular accident 151.57 9.91 238 288277 137345 64072872
Erythema 151.20 9.91 1387 287128 185683 64024534
Candida infection 150.75 9.91 392 288123 31027 64179190
Human herpesvirus 6 infection 147.66 9.91 140 288375 4514 64205703
Hypoglycaemia 147.09 9.91 112 288403 89780 64120437
Suicide attempt 146.47 9.91 67 288448 70940 64139277
Intentional product use issue 146.01 9.91 825 287690 94539 64115678
Fatigue 145.64 9.91 2416 286099 746314 63463903
Pneumomediastinum 144.59 9.91 113 288402 2787 64207430
Liver transplant rejection 143.37 9.91 114 288401 2885 64207332
Cystitis haemorrhagic 142.55 9.91 177 288338 7779 64202438
Acute respiratory distress syndrome 137.46 9.91 435 288080 38500 64171717
Blood pressure diastolic decreased 136.81 9.91 306 288209 21995 64188222
Injection site erythema 136.68 9.91 73 288442 70727 64139490
Cytomegalovirus chorioretinitis 135.73 9.91 137 288378 4775 64205442
Red cell distribution width increased 134.34 9.91 216 288299 12093 64198124
Drug intolerance 133.16 9.91 415 288100 187577 64022640
Multiple sclerosis relapse 132.99 9.91 446 288069 40689 64169528
Contraindicated product administered 130.08 9.91 175 288340 107654 64102563
Flushing 128.83 9.91 693 287822 77955 64132262
Abdominal discomfort 128.77 9.91 403 288112 181919 64028298
Acute graft versus host disease 128.57 9.91 180 288335 8904 64201313
Heart rate increased 127.67 9.91 817 287698 97858 64112359
Mycobacterium chelonae infection 123.63 9.91 91 288424 2046 64208171
Cushingoid 121.80 9.91 160 288355 7443 64202774
Arthropathy 121.50 9.91 222 288293 120745 64089472
Serotonin syndrome 121.42 9.91 16 288499 39266 64170951
Drug interaction 119.53 9.91 1040 287475 361043 63849174
Wound 119.21 9.91 100 288415 76377 64133840
Swelling 118.24 9.91 347 288168 159871 64050346
Varicella zoster virus infection 115.88 9.91 113 288402 3775 64206442
Cytomegalovirus colitis 114.90 9.91 113 288402 3815 64206402
Immunosuppressant drug level increased 113.57 9.91 151 288364 7108 64203109
Oedema peripheral 112.20 9.91 521 287994 209796 64000421
Orthostatic hypotension 111.57 9.91 35 288480 46703 64163514
Systemic mycosis 110.40 9.91 88 288427 2235 64207982
Pyrexia 109.64 9.91 3271 285244 555373 63654844
Hand deformity 109.52 9.91 73 288442 62698 64147519
Asthenia 108.92 9.91 1308 287207 426736 63783481
Chorioretinopathy 108.22 9.91 85 288430 2112 64208105
Intentional product misuse 107.29 9.91 99 288416 72196 64138021
Bacterial test 107.14 9.91 67 288448 1140 64209077
Constipation 107.07 9.91 595 287920 228742 63981475
Secondary immunodeficiency 106.18 9.91 92 288423 2632 64207585
Drug resistance 105.96 9.91 372 288143 34730 64175487
Acute graft versus host disease in intestine 105.89 9.91 104 288411 3505 64206712
Parvovirus B19 infection 105.53 9.91 67 288448 1172 64209045
Acinetobacter infection 104.86 9.91 87 288428 2342 64207875
Hyponatraemia 104.64 9.91 328 288187 148011 64062206
International normalised ratio increased 104.36 9.91 120 288395 79047 64131170
Loss of personal independence in daily activities 104.27 9.91 102 288413 72352 64137865
Peripheral swelling 104.10 9.91 531 287984 208622 64001595
Anti-cyclic citrullinated peptide antibody positive 103.41 9.91 46 288469 49516 64160701
Irritable bowel syndrome 102.63 9.91 21 288494 37348 64172869
Decreased appetite 102.34 9.91 787 287728 280502 63929715
Blood urine present 100.79 9.91 241 288274 18099 64192118
Pericarditis 99.60 9.91 80 288435 62436 64147781
Bacterial test positive 98.33 9.91 135 288380 6555 64203662
Protein urine present 97.52 9.91 157 288358 8799 64201418
Feeling hot 97.44 9.91 434 288081 45229 64164988
Coronary artery disease 96.69 9.91 77 288438 60356 64149861
Pemphigus 95.06 9.91 79 288436 60622 64149595
Enterobacter infection 94.73 9.91 99 288416 3597 64206620
Muscle injury 94.39 9.91 6 288509 26431 64183786
Urine ketone body present 92.78 9.91 93 288422 3214 64207003
Disease recurrence 92.59 9.91 331 288184 31179 64179038
Product prescribing error 92.46 9.91 22 288493 35247 64174970
Leukopenia 92.28 9.91 771 287744 100471 64109746
Diabetes mellitus 91.96 9.91 560 287955 65914 64144303
Staphylococcal sepsis 91.79 9.91 188 288327 12711 64197506
Epstein-Barr virus associated lymphoproliferative disorder 91.74 9.91 90 288425 3029 64207188
Myopathy 91.48 9.91 227 288288 17453 64192764
Osteonecrosis 91.18 9.91 306 288209 27923 64182294
Pulmonary mucormycosis 90.03 9.91 52 288463 760 64209457
Nephropathy toxic 89.70 9.91 224 288291 17290 64192927
Sedation 88.86 9.91 37 288478 41425 64168792
Injection site swelling 88.47 9.91 37 288478 41316 64168901
Accidental exposure to product 88.43 9.91 8 288507 26356 64183861
Blood pressure diastolic increased 87.76 9.91 166 288349 10586 64199631
Diffuse alveolar damage 87.15 9.91 89 288426 3146 64207071
Cytomegalovirus enteritis 86.94 9.91 48 288467 640 64209577
Hyperglycaemia 85.86 9.91 516 287999 60452 64149765
Pulmonary alveolar haemorrhage 85.32 9.91 155 288360 9583 64200634
Intentional self-injury 84.75 9.91 14 288501 29030 64181187
Haemoglobin urine present 84.50 9.91 51 288464 812 64209405
Discomfort 84.29 9.91 145 288370 80733 64129484
Renal transplant failure 84.15 9.91 65 288450 1575 64208642
Rhabdomyolysis 82.92 9.91 179 288336 91547 64118670
Pain 81.99 9.91 1869 286646 551642 63658575
Culture urine positive 81.95 9.91 97 288418 4054 64206163
Chronic allograft nephropathy 81.81 9.91 62 288453 1459 64208758
Focal segmental glomerulosclerosis 81.14 9.91 82 288433 2862 64207355
Anaphylactic shock 81.07 9.91 309 288206 30019 64180198
Psoriasis 80.88 9.91 122 288393 71581 64138636
Duodenal ulcer perforation 80.75 9.91 27 288488 34598 64175619
Acute graft versus host disease in liver 80.37 9.91 64 288451 1623 64208594
Herpes simplex 80.28 9.91 158 288357 10378 64199839
Sepsis 79.88 9.91 1461 287054 228880 63981337
Monocyte percentage increased 78.87 9.91 68 288447 1932 64208285
Bacterial sepsis 78.85 9.91 129 288386 7328 64202889
Accidental overdose 78.55 9.91 26 288489 33531 64176686
Pseudomonal sepsis 78.49 9.91 106 288409 5066 64205151
Hypertension 78.24 9.91 1610 286905 257651 63952566
Device expulsion 77.91 9.91 4 288511 21132 64189085
Pneumocystis jirovecii infection 76.77 9.91 72 288443 2289 64207928
Escherichia infection 76.64 9.91 193 288322 14975 64195242
Injection site pruritus 75.99 9.91 37 288478 37789 64172428
Injection site bruising 75.50 9.91 34 288481 36339 64173878
Injection site reaction 75.23 9.91 59 288456 46605 64163612
Ear pruritus 74.99 9.91 75 288440 2585 64207632
Therapy non-responder 74.05 9.91 527 287988 65372 64144845
Neutrophil count increased 73.59 9.91 264 288251 24910 64185307
Fungal infection 73.42 9.91 326 288189 33925 64176292
Cytomegalovirus enterocolitis 72.36 9.91 55 288460 1300 64208917
Mycobacterium abscessus infection 72.15 9.91 49 288466 965 64209252
Drug effective for unapproved indication 72.13 9.91 86 288429 3622 64206595
Rheumatoid factor positive 71.99 9.91 33 288482 34905 64175312
Psoriatic arthropathy 71.98 9.91 53 288462 43228 64166989
Febrile bone marrow aplasia 71.93 9.91 157 288358 11098 64199119
Reversible cerebral vasoconstriction syndrome 71.55 9.91 69 288446 2273 64207944
Viraemia 71.37 9.91 69 288446 2280 64207937
Lethargy 71.30 9.91 135 288380 72459 64137758
Specific gravity urine decreased 70.86 9.91 44 288471 739 64209478
Renal tubular atrophy 70.70 9.91 57 288458 1472 64208745
Serum sickness 70.49 9.91 79 288436 3110 64207107
Vasculitis 70.23 9.91 209 288306 17886 64192331
Necrotising retinitis 70.06 9.91 49 288466 1014 64209203
Transient ischaemic attack 69.80 9.91 57 288458 44125 64166092
Proteinuria 69.66 9.91 277 288238 27446 64182771
Temperature regulation disorder 69.61 9.91 90 288425 4121 64206096
Opportunistic infection 69.48 9.91 72 288443 2590 64207627
Cryptococcosis 69.19 9.91 73 288442 2682 64207535
Rheumatoid arthritis 68.96 9.91 1075 287440 163219 64046998
Intensive care unit acquired weakness 68.68 9.91 59 288456 1668 64208549
Chronic graft versus host disease 68.31 9.91 110 288405 6166 64204051
Immunodeficiency 68.14 9.91 192 288323 15932 64194285
Sopor 67.66 9.91 24 288491 29637 64180580
Rebound effect 67.47 9.91 96 288419 4821 64205396
Systemic lupus erythematosus 67.25 9.91 155 288360 77457 64132760
Product quality issue 66.47 9.91 25 288490 29774 64180443
Adverse event 66.13 9.91 48 288467 39441 64170776
Granulomatosis with polyangiitis 65.79 9.91 63 288452 2057 64208160
Contusion 65.77 9.91 274 288241 113691 64096526
C-reactive protein abnormal 65.42 9.91 24 288491 29023 64181194
Helicobacter infection 65.07 9.91 46 288469 38316 64171901
Therapy cessation 64.93 9.91 32 288483 32457 64177760
Dyspnoea 64.03 9.91 2598 285917 716076 63494141
Viral haemorrhagic cystitis 63.29 9.91 55 288460 1580 64208637
Pain in extremity 63.28 9.91 964 287551 302121 63908096
Systemic candida 62.98 9.91 97 288418 5232 64204985
Human herpesvirus 8 infection 62.77 9.91 46 288469 1027 64209190
Renal tubular necrosis 62.20 9.91 229 288286 21881 64188336
Gastroenteritis norovirus 61.78 9.91 69 288446 2706 64207511
Stomatitis 61.11 9.91 267 288248 109338 64100879
Drug hypersensitivity 61.01 9.91 725 287790 237090 63973127
Bacterial infection 60.86 9.91 247 288268 24703 64185514
Infection reactivation 60.50 9.91 59 288456 1971 64208246
Immunosuppressant drug level decreased 60.27 9.91 56 288459 1759 64208458
Dural arteriovenous fistula 59.84 9.91 18 288497 36 64210181
Multiple sclerosis 59.13 9.91 203 288312 18738 64191479
JC virus infection 59.08 9.91 74 288441 3281 64206936
General physical health deterioration 58.86 9.91 607 287908 203818 64006399
COVID-19 58.77 9.91 495 288020 64645 64145572
Adverse drug reaction 58.74 9.91 70 288445 45394 64164823
Poisoning 58.64 9.91 13 288502 21866 64188351
Acute kidney injury 58.24 9.91 1547 286968 447693 63762524
Systemic inflammatory response syndrome 57.87 9.91 136 288379 10099 64200118
Device issue 57.67 9.91 15 288500 22633 64187584
Disseminated mucormycosis 57.57 9.91 33 288482 475 64209742
Osteonecrosis of jaw 57.37 9.91 56 288459 39769 64170448
Hypogammaglobulinaemia 57.30 9.91 136 288379 10163 64200054
Haemolytic anaemia 57.24 9.91 180 288335 15873 64194344
Thrombocytopenia 56.48 9.91 1355 287160 222446 63987771
Nitrite urine present 56.12 9.91 43 288472 1029 64209188
Graft versus host disease in liver 55.97 9.91 50 288465 1491 64208726
Ureaplasma infection 55.72 9.91 37 288478 701 64209516
Neuroleptic malignant syndrome 55.71 9.91 21 288494 24975 64185242
Immune thrombocytopenia 55.63 9.91 171 288344 14895 64195322
Chest discomfort 55.48 9.91 777 287738 115329 64094888
Bacteraemia 55.33 9.91 253 288262 26658 64183559
Device malfunction 54.93 9.91 7 288508 17626 64192591
Transplant failure 54.92 9.91 76 288439 3718 64206499
Diffuse large B-cell lymphoma 54.63 9.91 134 288381 10227 64199990
Respiratory arrest 54.29 9.91 96 288419 52889 64157328
Malignant neoplasm progression 54.18 9.91 290 288225 112581 64097636
Central nervous system infection 54.13 9.91 44 288471 1150 64209067
Unresponsive to stimuli 53.74 9.91 89 288426 50304 64159913
Product substitution issue 53.49 9.91 8 288507 17853 64192364
Specific gravity urine increased 53.31 9.91 30 288485 416 64209801
Hypophagia 53.26 9.91 59 288456 39528 64170689
Staphylococcal infection 52.76 9.91 398 288117 50280 64159937
Listeriosis 52.71 9.91 54 288461 1916 64208301
COVID-19 pneumonia 52.50 9.91 178 288337 16326 64193891
Infective aneurysm 52.17 9.91 38 288477 840 64209377
Electric shock 52.02 9.91 42 288473 1087 64209130
Premature delivery 51.84 9.91 192 288323 18397 64191820
Suicidal ideation 51.35 9.91 141 288374 66401 64143816
Respiratory rate increased 50.84 9.91 189 288326 18142 64192075
Feeling abnormal 50.80 9.91 369 288146 133233 64076984
Hyperkalaemia 50.69 9.91 256 288259 100873 64109344
Blood thyroid stimulating hormone decreased 50.67 9.91 87 288428 5143 64205074
Depressed level of consciousness 50.66 9.91 190 288325 81246 64128971
Pneumonia cryptococcal 50.64 9.91 43 288472 1196 64209021
Knee arthroplasty 50.42 9.91 29 288486 26970 64183247
Lupus nephritis 50.11 9.91 58 288457 2366 64207851
Urticaria 49.83 9.91 931 287584 146386 64063831
Central nervous system fungal infection 49.40 9.91 28 288487 394 64209823
Candida sepsis 48.92 9.91 55 288460 2173 64208044
Pneumonia fungal 48.07 9.91 116 288399 8761 64201456
Herpes zoster 48.07 9.91 554 287961 78633 64131584
Therapy interrupted 47.82 9.91 15 288500 20021 64190196
Kidney fibrosis 47.74 9.91 64 288451 3037 64207180
Glomerulonephritis 47.49 9.91 62 288453 2866 64207351
Drug withdrawal syndrome 47.43 9.91 42 288473 31249 64178968
Perinephric abscess 47.34 9.91 22 288493 198 64210019
Substance-induced psychotic disorder 47.30 9.91 60 288455 2695 64207522
Myalgia 46.88 9.91 468 288047 158149 64052068
Oral herpes 46.84 9.91 210 288305 21942 64188275
Glomerulosclerosis 46.81 9.91 37 288478 928 64209289
Pulmonary haemorrhage 46.75 9.91 147 288368 12962 64197255
Pharyngeal paraesthesia 46.74 9.91 50 288465 1867 64208350
Mobility decreased 46.70 9.91 211 288304 85629 64124588
Stenotrophomonas infection 46.55 9.91 63 288452 3017 64207200
Chest pain 46.38 9.91 759 287756 235221 63974996
Necrosis ischaemic 46.21 9.91 37 288478 946 64209271
Malaise 45.60 9.91 1387 287128 394860 63815357
Coma 45.52 9.91 219 288296 87396 64122821
Encephalitis cytomegalovirus 45.49 9.91 37 288478 968 64209249
Pulmonary nocardiosis 45.44 9.91 33 288482 726 64209491
Injection site haemorrhage 45.44 9.91 26 288489 24252 64185965
Treatment noncompliance 45.26 9.91 78 288437 43404 64166813
Surgery 45.06 9.91 36 288479 28177 64182040
Intra-abdominal pressure increased 44.91 9.91 22 288493 225 64209992
Large intestine perforation 44.64 9.91 141 288374 12463 64197754
Aggression 44.50 9.91 87 288428 46145 64164072
Haemolytic uraemic syndrome 44.48 9.91 71 288444 3950 64206267
Monocyte count increased 44.21 9.91 106 288409 7973 64202244
Hepatocellular injury 44.17 9.91 350 288165 44885 64165332
Human bocavirus infection 44.01 9.91 29 288486 542 64209675
Acute myocardial infarction 43.80 9.91 162 288353 69556 64140661
Pneumonia acinetobacter 43.45 9.91 18 288497 119 64210098
Amoebic colitis 43.15 9.91 16 288499 75 64210142
Muscle spasms 42.97 9.91 413 288102 140610 64069607
Food allergy 42.95 9.91 103 288412 7748 64202469
Pneumonia pseudomonal 42.90 9.91 78 288437 4825 64205392
Osteomyelitis fungal 42.68 9.91 22 288493 253 64209964
Red blood cells urine 42.64 9.91 30 288485 627 64209590
Full blood count decreased 42.53 9.91 24 288491 22558 64187659
Intervertebral discitis 42.52 9.91 68 288447 3789 64206428
Nephrotic syndrome 42.48 9.91 116 288399 9451 64200766
Memory impairment 42.31 9.91 218 288297 85464 64124753
Bone pain 42.02 9.91 94 288421 47478 64162739
West Nile viral infection 42.01 9.91 34 288481 883 64209334
Atrial fibrillation 41.80 9.91 527 287988 170562 64039655
Cardiac disorder 41.78 9.91 120 288395 55696 64154521
Pulmonary hypertension 41.68 9.91 81 288434 43058 64167159
Full blood count abnormal 41.53 9.91 43 288472 29714 64180503
Urinary casts 41.08 9.91 36 288479 1046 64209171
Plasma cell myeloma 40.73 9.91 91 288424 45984 64164233
Penicillium infection 40.54 9.91 20 288495 208 64210009
Injection site warmth 40.39 9.91 6 288509 13456 64196761
Central nervous system viral infection 40.34 9.91 16 288499 93 64210124
Corynebacterium infection 40.25 9.91 34 288481 939 64209278
Blister 39.98 9.91 206 288309 80761 64129456
Peritonitis 39.94 9.91 219 288296 24804 64185413
Disseminated tuberculosis 39.82 9.91 64 288451 3581 64206636
Mycoplasma infection 39.82 9.91 29 288486 641 64209576
Loss of consciousness 39.69 9.91 448 288067 147917 64062300
Extrapyramidal disorder 39.46 9.91 19 288496 19533 64190684
Epstein-Barr virus associated lymphoma 39.41 9.91 33 288482 900 64209317
Injection site mass 39.35 9.91 14 288501 17256 64192961
Sleep disorder 39.33 9.91 136 288379 59573 64150644
Phaeohyphomycosis 39.31 9.91 35 288480 1039 64209178
Red blood cell sedimentation rate abnormal 39.29 9.91 12 288503 16294 64193923
Cerebral aspergillosis 39.25 9.91 43 288472 1650 64208567
Hallucination 38.95 9.91 180 288335 72608 64137609
Gait disturbance 38.87 9.91 539 287976 171616 64038601
Epstein-Barr viraemia 38.84 9.91 44 288471 1753 64208464
Pathogen resistance 38.78 9.91 134 288381 12409 64197808
Epstein-Barr virus infection reactivation 38.76 9.91 36 288479 1130 64209087
Abscess bacterial 38.69 9.91 30 288485 731 64209486
Anaemia 38.67 9.91 1346 287169 377334 63832883
Herpes virus infection 38.65 9.91 86 288429 6158 64204059
Cytokine release syndrome 38.58 9.91 190 288325 20639 64189578
Toxoplasmosis 38.48 9.91 51 288464 2393 64207824
Disseminated cryptococcosis 38.43 9.91 41 288474 1526 64208691
Pneumothorax 38.34 9.91 212 288303 24086 64186131
Incision site pain 38.17 9.91 53 288462 2601 64207616
Body temperature decreased 38.13 9.91 222 288293 25706 64184511
Ureteric stenosis 38.11 9.91 37 288478 1229 64208988
Symptom masked 37.78 9.91 36 288479 1168 64209049
Cytomegalovirus oesophagitis 37.62 9.91 27 288488 583 64209634
Band sensation 37.60 9.91 28 288487 641 64209576
Neuropathy peripheral 37.60 9.91 340 288175 117185 64093032
Haematemesis 37.46 9.91 98 288417 46901 64163316
Miosis 37.38 9.91 7 288508 13259 64196958
Intestinal ischaemia 37.12 9.91 125 288390 11424 64198793
Abdominal infection 36.85 9.91 55 288460 2885 64207332
Lung abscess 36.78 9.91 61 288454 3505 64206712
Labelled drug-drug interaction medication error 36.70 9.91 27 288488 22035 64188182
Therapeutic response decreased 36.70 9.91 376 288139 51812 64158405
Demyelination 36.68 9.91 89 288426 6745 64203472
Thyroxine free increased 36.46 9.91 34 288481 1073 64209144
Pleocytosis 36.46 9.91 34 288481 1073 64209144
Cardio-respiratory arrest 36.32 9.91 274 288241 98119 64112098
Blood glucose decreased 36.31 9.91 30 288485 23093 64187124
Bilirubin urine present 36.23 9.91 21 288494 309 64209908
Steroid withdrawal syndrome 36.08 9.91 27 288488 623 64209594
Mean cell haemoglobin increased 36.05 9.91 57 288458 3145 64207072
Encephalitis 36.03 9.91 131 288384 12440 64197777
Pain in jaw 35.61 9.91 81 288434 40674 64169543
Product storage error 35.52 9.91 8 288507 13310 64196907
Hypoalbuminaemia 35.47 9.91 165 288350 17509 64192708
C-reactive protein increased 35.33 9.91 609 287906 94300 64115917
Cardiac failure 35.29 9.91 400 288115 131973 64078244
Complications of transplant surgery 35.13 9.91 28 288487 711 64209506
Sedation complication 35.11 9.91 3 288512 10351 64199866
Necrotising herpetic retinopathy 34.90 9.91 15 288500 110 64210107
Gastroenteritis rotavirus 34.89 9.91 22 288493 380 64209837
Chills 34.87 9.91 832 287683 136432 64073785
Dyskinesia 34.65 9.91 78 288437 39310 64170907
Aplasia 34.63 9.91 88 288427 6865 64203352
Nightmare 34.53 9.91 26 288489 20967 64189250
Incorrect dose administered 34.48 9.91 147 288368 60618 64149599
Quadriplegia 34.43 9.91 54 288461 2959 64207258
Oesophageal candidiasis 34.40 9.91 96 288419 7921 64202296
Gastrooesophageal reflux disease 34.38 9.91 224 288291 82919 64127298
Rectal haemorrhage 34.19 9.91 151 288364 61666 64148551
Fungaemia 34.12 9.91 61 288454 3724 64206493
Mean cell haemoglobin decreased 34.09 9.91 64 288451 4058 64206159
Steroid dependence 34.06 9.91 22 288493 397 64209820
Coronavirus infection 34.05 9.91 76 288439 5454 64204763
Coeliac disease 34.04 9.91 91 288424 7321 64202896
Mean cell haemoglobin concentration decreased 34.02 9.91 60 288455 3624 64206593
Rash erythematous 34.01 9.91 350 288165 48283 64161934
Cerebral venous thrombosis 34.00 9.91 48 288467 2393 64207824
Blood immunoglobulin M decreased 33.92 9.91 31 288484 953 64209264
Electrocardiogram QT prolonged 33.90 9.91 212 288303 79236 64130981
Injection site rash 33.81 9.91 14 288501 15728 64194489
Porphyria acute 33.63 9.91 27 288488 693 64209524
Joint swelling 33.55 9.91 721 287794 214661 63995556
Haemodynamic instability 33.53 9.91 144 288371 14768 64195449
Therapeutic product effect decreased 33.39 9.91 342 288173 115009 64095208
American trypanosomiasis 33.38 9.91 20 288495 314 64209903
B-lymphocyte count decreased 33.22 9.91 33 288482 1128 64209089
Fusarium infection 33.20 9.91 38 288477 1531 64208686
Respiratory distress 33.05 9.91 369 288146 51962 64158255
Cryptococcal meningoencephalitis 33.02 9.91 17 288498 195 64210022
Lower respiratory tract infection 32.81 9.91 268 288247 94346 64115871
Device difficult to use 32.79 9.91 3 288512 9795 64200422
Kaposi's sarcoma 32.69 9.91 27 288488 722 64209495
Optic neuritis 32.69 9.91 95 288420 8021 64202196
Herpes simplex colitis 32.61 9.91 10 288505 22 64210195
Lower limb fracture 32.58 9.91 10 288505 13535 64196682
Engraftment syndrome 32.52 9.91 32 288483 1081 64209136
Band neutrophil percentage increased 32.41 9.91 21 288494 381 64209836
Hepatic cirrhosis 32.39 9.91 42 288473 26256 64183961
Cytomegalovirus gastrointestinal infection 32.36 9.91 22 288493 434 64209783
Right ventricular failure 32.32 9.91 29 288486 21442 64188775
Urobilinogen urine increased 32.32 9.91 25 288490 607 64209610
Brain abscess 32.22 9.91 63 288452 4118 64206099
Pneumonia bacterial 32.14 9.91 143 288372 14892 64195325
Abdominal pain upper 32.09 9.91 570 287945 174460 64035757
Torsade de pointes 31.92 9.91 19 288496 17344 64192873
Disseminated varicella zoster vaccine virus infection 31.86 9.91 14 288501 109 64210108
Shock haemorrhagic 31.69 9.91 154 288361 16637 64193580
Perforation 31.68 9.91 32 288483 1116 64209101
Gastrointestinal disorder 31.62 9.91 253 288262 89456 64120761
Dystonia 31.50 9.91 23 288492 18842 64191375
Pedal pulse abnormal 31.44 9.91 15 288500 144 64210073
Graft loss 31.39 9.91 30 288485 977 64209240
Osteoarthritis 31.35 9.91 161 288354 63175 64147042
Dyspnoea exertional 31.32 9.91 197 288318 73533 64136684
Cutaneous mucormycosis 31.12 9.91 14 288501 116 64210101
Central nervous system lesion 31.07 9.91 120 288395 11729 64198488
Rhinocerebral mucormycosis 30.97 9.91 22 288493 467 64209750
Urine leukocyte esterase 30.92 9.91 15 288500 150 64210067
Skin striae 30.88 9.91 35 288480 1395 64208822
IgA nephropathy 30.80 9.91 35 288480 1399 64208818
Renal impairment 30.62 9.91 806 287709 134211 64076006
Needle issue 30.60 9.91 3 288512 9269 64200948
Hepatitis 30.44 9.91 325 288190 45257 64164960
Folliculitis 30.35 9.91 55 288460 30022 64180195
Blood calcium decreased 30.27 9.91 42 288473 25512 64184705
Segmental diverticular colitis 30.22 9.91 14 288501 125 64210092
Tardive dyskinesia 30.21 9.91 3 288512 9175 64201042
Adrenal insufficiency 30.18 9.91 188 288327 22299 64187918
Swollen tongue 30.11 9.91 70 288445 34884 64175333
Inappropriate schedule of product administration 29.94 9.91 266 288249 92020 64118197
Somnolence 29.91 9.91 688 287827 202957 64007260
Malacoplakia gastrointestinal 29.84 9.91 15 288500 163 64210054
Infective pulmonary exacerbation of cystic fibrosis 29.68 9.91 8 288507 11788 64198429
Hypocalcaemia 29.64 9.91 92 288423 41661 64168556
Enthesopathy 29.61 9.91 4 288511 9634 64200583
Blood beta-D-glucan increased 29.46 9.91 22 288493 506 64209711
Obliterative bronchiolitis 29.40 9.91 47 288468 2618 64207599
Thunderclap headache 29.20 9.91 16 288499 210 64210007
Neuralgia 29.17 9.91 209 288306 25975 64184242
Smear cervix abnormal 29.17 9.91 44 288471 2330 64207887
Red blood cell count increased 29.15 9.91 55 288460 3500 64206717
Weight increased 29.08 9.91 1199 287316 212149 63998068
Clostridium difficile colitis 29.01 9.91 215 288300 27008 64183209
Escherichia sepsis 28.99 9.91 84 288431 7081 64203136
Apoptosis 28.90 9.91 18 288497 304 64209913
Enterococcus test positive 28.89 9.91 37 288478 1678 64208539
Bronchopleural fistula 28.76 9.91 23 288492 587 64209630
Disorientation 28.73 9.91 140 288375 55688 64154529
Hip arthroplasty 28.52 9.91 32 288483 21319 64188898
Monocyte count decreased 28.30 9.91 48 288467 2809 64207408
Cells in urine 28.26 9.91 15 288500 184 64210033
Unevaluable event 28.12 9.91 123 288392 50366 64159851
Underdose 28.11 9.91 45 288470 25784 64184433
Abnormal dreams 28.06 9.91 6 288509 10350 64199867
Leukocytosis 28.02 9.91 275 288240 37465 64172752
Poor venous access 27.99 9.91 120 288395 12297 64197920
Intestinal perforation 27.87 9.91 139 288376 15174 64195043
Blood immunoglobulin G decreased 27.81 9.91 46 288469 2637 64207580
Encephalitis autoimmune 27.66 9.91 38 288477 1846 64208371
Eosinophil percentage increased 27.65 9.91 33 288482 1391 64208826
Red cell distribution width decreased 27.52 9.91 29 288486 1064 64209153
Natural killer-cell leukaemia 27.47 9.91 12 288503 92 64210125
Pneumoperitoneum 27.46 9.91 46 288469 2665 64207552
Human polyomavirus infection 27.39 9.91 28 288487 991 64209226
Hepatic artery thrombosis 27.35 9.91 17 288498 286 64209931
Neurological decompensation 27.35 9.91 61 288454 4375 64205842
Head injury 27.32 9.91 67 288448 32775 64177442
Respiratory depression 27.30 9.91 39 288476 23404 64186813
Blood loss anaemia 27.28 9.91 14 288501 13878 64196339
Parvovirus infection 27.16 9.91 22 288493 572 64209645
Palmar-plantar erythrodysaesthesia syndrome 27.07 9.91 55 288460 28764 64181453
Listeria encephalitis 27.05 9.91 17 288498 292 64209925
Laryngeal stenosis 26.99 9.91 25 288490 782 64209435
Heart transplant rejection 26.95 9.91 31 288484 1256 64208961
Device dislocation 26.94 9.91 33 288482 21145 64189072
Pneumatosis 26.75 9.91 25 288490 791 64209426
Metastases to liver 26.74 9.91 41 288474 23900 64186317
Urinary retention 26.72 9.91 121 288394 49080 64161137
Product administration error 26.62 9.91 52 288463 27591 64182626
Product dispensing error 26.57 9.91 9 288506 11441 64198776
Transplant dysfunction 26.52 9.91 78 288437 6630 64203587
Type I hypersensitivity 26.51 9.91 53 288462 3521 64206696
Magnetic resonance imaging abnormal 26.46 9.91 49 288466 3074 64207143
Aspergillosis oral 26.45 9.91 10 288505 50 64210167
Intestine transplant rejection 26.39 9.91 11 288504 74 64210143
Sleep disorder due to a general medical condition 26.31 9.91 3 288512 8231 64201986
Road traffic accident 26.14 9.91 62 288453 30683 64179534
Multiple-drug resistance 26.09 9.91 76 288439 6426 64203791
Lung transplant rejection 26.09 9.91 31 288484 1301 64208916
Reticulocytosis 26.05 9.91 20 288495 480 64209737
Pyelonephritis fungal 26.02 9.91 12 288503 106 64210111
Status epilepticus 25.95 9.91 176 288339 21487 64188730
Lip pruritus 25.85 9.91 23 288492 682 64209535
Feeding intolerance 25.77 9.91 21 288494 551 64209666
Leukocyturia 25.62 9.91 33 288482 1505 64208712
Sense of oppression 25.61 9.91 32 288483 1415 64208802
Mean cell haemoglobin concentration increased 25.59 9.91 24 288491 763 64209454
Monocytopenia 25.56 9.91 13 288502 145 64210072
Pneumonia klebsiella 25.44 9.91 56 288459 3981 64206236
Band neutrophil count increased 25.28 9.91 22 288493 633 64209584
Bronchospasm 25.28 9.91 175 288340 21507 64188710
Graft complication 25.26 9.91 22 288493 634 64209583
Femur fracture 25.10 9.91 74 288441 34061 64176156
Angiocentric lymphoma 25.08 9.91 24 288491 783 64209434
Cardiac arrest 25.07 9.91 512 288003 153552 64056665
Condition aggravated 24.86 9.91 1961 286554 370465 63839752
Pancytopenia 24.75 9.91 827 287688 142482 64067735
Medication error 24.74 9.91 127 288388 49839 64160378
Leukoencephalopathy 24.73 9.91 78 288437 6889 64203328
Drug level below therapeutic 24.69 9.91 81 288434 7303 64202914
Haemoglobin urine 24.65 9.91 12 288503 121 64210096
Fungal skin infection 24.63 9.91 64 288451 5061 64205156
Autoimmune thyroiditis 24.61 9.91 51 288464 3477 64206740
Withdrawal syndrome 24.57 9.91 42 288473 23450 64186767
Arteriosclerosis coronary artery 24.57 9.91 20 288495 15509 64194708
Neoplasm progression 24.55 9.91 97 288418 40867 64169350
Serratia infection 24.48 9.91 32 288483 1481 64208736
Haemolysis 24.36 9.91 106 288409 10933 64199284
Polyomavirus viraemia 24.35 9.91 28 288487 1134 64209083
Tachycardia 24.27 9.91 857 287658 148722 64061495
Oliguria 24.23 9.91 129 288386 14447 64195770
Hepatitis B 24.17 9.91 83 288432 7662 64202555
Device leakage 24.08 9.91 4 288511 8262 64201955
Blood potassium increased 24.05 9.91 50 288465 25930 64184287
pH urine increased 24.03 9.91 18 288497 416 64209801
Pregnancy 24.01 9.91 35 288480 20830 64189387
Antineutrophil cytoplasmic antibody positive 23.98 9.91 26 288489 986 64209231
Atrioventricular block first degree 23.95 9.91 9 288506 10725 64199492
Injection site urticaria 23.92 9.91 10 288505 11171 64199046
Neuromyelitis optica spectrum disorder 23.86 9.91 24 288491 833 64209384
Hospice care 23.82 9.91 3 288512 7622 64202595
CSF protein increased 23.79 9.91 27 288488 1078 64209139
Microsporidia infection 23.74 9.91 23 288492 762 64209455
Disseminated strongyloidiasis 23.67 9.91 11 288504 99 64210118
Mean cell volume decreased 23.66 9.91 50 288465 3456 64206761
Thrombosis 23.63 9.91 202 288313 70440 64139777
Parainfluenzae virus infection 23.59 9.91 60 288455 4683 64205534
Blood lactate dehydrogenase increased 23.58 9.91 239 288276 32839 64177378
Encephalopathy 23.56 9.91 382 288133 58437 64151780
Product complaint 23.54 9.91 12 288503 11942 64198275
Adenoviral haemorrhagic cystitis 23.52 9.91 19 288496 492 64209725
Akathisia 23.51 9.91 11 288504 11499 64198718
Atypical mycobacterial pneumonia 23.51 9.91 12 288503 135 64210082
Body temperature fluctuation 23.38 9.91 48 288467 3250 64206967
Parkinsonism 23.38 9.91 18 288497 14355 64195862
Therapeutic product effect incomplete 23.34 9.91 324 288191 103158 64107059
Pulmonary arterial hypertension 23.33 9.91 49 288466 25318 64184899
Eschar 23.28 9.91 27 288488 1104 64209113
Autoimmune hepatitis 23.15 9.91 98 288417 9986 64200231
Anorectal ulcer 23.03 9.91 9 288506 50 64210167
Non-consummation 23.03 9.91 9 288506 50 64210167
Toxic epidermal necrolysis 22.98 9.91 261 288254 36905 64173312
Erectile dysfunction 22.96 9.91 14 288501 12613 64197604
Transfusion 22.93 9.91 28 288487 17966 64192251
Cataract 22.86 9.91 339 288176 50923 64159294
Scopulariopsis infection 22.85 9.91 11 288504 108 64210109
Bacillus infection 22.83 9.91 22 288493 724 64209493
Thymus hypoplasia 22.82 9.91 19 288496 514 64209703
Lymphoproliferative disorder 22.78 9.91 62 288453 5041 64205176
Meningitis cryptococcal 22.77 9.91 45 288470 2964 64207253
Biloma 22.76 9.91 12 288503 145 64210072
Retinal detachment 22.76 9.91 83 288432 7893 64202324
Cytomegalovirus hepatitis 22.65 9.91 20 288495 587 64209630
Central nervous system lymphoma 22.56 9.91 35 288480 1900 64208317
Factor XIII deficiency 22.53 9.91 10 288505 80 64210137
Dermatomyositis 22.50 9.91 43 288472 2763 64207454
Lymphocele 22.46 9.91 32 288483 1609 64208608
Presyncope 22.39 9.91 81 288434 35008 64175209
Breast cancer 22.31 9.91 62 288453 29086 64181131
Pancreas transplant rejection 22.28 9.91 15 288500 291 64209926
Angiosarcoma 22.22 9.91 17 288498 406 64209811
Blood albumin increased 22.19 9.91 29 288486 1342 64208875
Depression 22.17 9.91 637 287878 182654 64027563
Herpes simplex viraemia 22.15 9.91 14 288501 243 64209974
Pneumoretroperitoneum 22.01 9.91 10 288505 85 64210132
Prostate cancer 22.01 9.91 34 288481 19761 64190456
Periumbilical abscess 21.79 9.91 9 288506 59 64210158
Pyelonephritis 21.72 9.91 142 288373 17124 64193093
Atypical mycobacterial infection 21.69 9.91 28 288487 1280 64208937
Rubella antibody positive 21.66 9.91 9 288506 60 64210157
Urinary tract infection bacterial 21.65 9.91 61 288454 5060 64205157
Prescribed overdose 21.59 9.91 36 288479 20295 64189922
Pyelonephritis acute 21.56 9.91 61 288454 5073 64205144
Immunoglobulins decreased 21.52 9.91 28 288487 1290 64208927
Blood creatinine decreased 21.52 9.91 75 288440 6975 64203242
Eosinophil percentage decreased 21.51 9.91 14 288501 256 64209961
Viral cardiomyopathy 21.49 9.91 8 288507 38 64210179
Bundle branch block left 21.43 9.91 9 288506 10025 64200192
Blood brain barrier defect 21.30 9.91 11 288504 127 64210090
Blindness cortical 21.24 9.91 22 288493 791 64209426
White blood cell count increased 21.21 9.91 414 288101 65600 64144617
Urinary tract candidiasis 21.19 9.91 20 288495 641 64209576
Orbital apex syndrome 21.17 9.91 9 288506 64 64210153
Cestode infection 21.14 9.91 14 288501 264 64209953
Body temperature increased 21.12 9.91 254 288261 36412 64173805
Viral infection 21.10 9.91 251 288264 35889 64174328
Infusion site extravasation 21.10 9.91 73 288442 6764 64203453
Myoclonus 21.08 9.91 51 288464 25067 64185150
Poikiloderma 21.05 9.91 15 288500 320 64209897
Premenstrual syndrome 21.04 9.91 18 288497 506 64209711
Pseudomonal bacteraemia 21.01 9.91 37 288478 2232 64207985
Rhinovirus infection 21.01 9.91 68 288447 6088 64204129
Lipaemic index score 21.00 9.91 11 288504 131 64210086
Aplastic anaemia 21 9.91 120 288395 13800 64196417
Meningitis fungal 20.98 9.91 12 288503 172 64210045
Heart rate irregular 20.97 9.91 201 288314 27212 64183005
Menstruation irregular 20.92 9.91 55 288460 4380 64205837
Hepatic function abnormal 20.89 9.91 404 288111 63909 64146308
Meningoencephalitis viral 20.88 9.91 16 288499 383 64209834
Enteritis 20.84 9.91 108 288407 11969 64198248
Malacoplakia vesicae 20.83 9.91 9 288506 67 64210150
Partial seizures 20.82 9.91 76 288439 7231 64202986
Bradyphrenia 20.80 9.91 8 288507 9398 64200819
Serum ferritin increased 20.78 9.91 84 288431 8384 64201833
Tuberculosis 20.73 9.91 114 288401 12924 64197293
Urine bilirubin decreased 20.72 9.91 11 288504 135 64210082
Blood creatine phosphokinase increased 20.70 9.91 165 288350 58393 64151824
Morganella infection 20.68 9.91 24 288491 982 64209235
Oral pain 20.65 9.91 59 288456 27434 64182783
Sideroblastic anaemia 20.65 9.91 13 288502 224 64209993
Aphthous ulcer 20.63 9.91 113 288402 12793 64197424
Calcium ionised decreased 20.63 9.91 18 288497 520 64209697
Engraft failure 20.57 9.91 19 288496 592 64209625
Neutropenic sepsis 20.54 9.91 46 288469 23226 64186991
Hepatitis cholestatic 20.50 9.91 108 288407 12047 64198170
Subdural haematoma 20.50 9.91 61 288454 27993 64182224
Tri-iodothyronine free increased 20.45 9.91 13 288502 228 64209989
Renal graft infection 20.39 9.91 16 288499 397 64209820
Gastrointestinal mucormycosis 20.39 9.91 15 288500 337 64209880
Capillaritis 20.30 9.91 13 288502 231 64209986
Red blood cell schistocytes present 20.28 9.91 18 288497 532 64209685
Myelitis 20.26 9.91 35 288480 2079 64208138
Anti-thyroid antibody positive 20.26 9.91 17 288498 465 64209752
Electrocardiogram QRS complex prolonged 20.21 9.91 8 288507 9236 64200981
Impaired healing 20.19 9.91 173 288342 60300 64149917
Acute disseminated encephalomyelitis 20.17 9.91 14 288501 286 64209931
Meningitis bacterial 20.15 9.91 37 288478 2306 64207911
Peripheral vascular disorder 20.10 9.91 4 288511 7257 64202960
Hepatic failure 20.09 9.91 354 288161 55040 64155177
Cystitis bacterial 20.05 9.91 16 288499 407 64209810
Brain oedema 20.03 9.91 168 288347 21907 64188310
Aplasia pure red cell 20.02 9.91 73 288442 6941 64203276
Lymphoid tissue hypoplasia 19.99 9.91 17 288498 474 64209743
Mental status changes 19.96 9.91 176 288339 60986 64149231
Angina unstable 19.78 9.91 24 288491 15443 64194774
Alveolitis 19.73 9.91 48 288467 3644 64206573
Q fever 19.72 9.91 12 288503 194 64210023
Cholelithiasis 19.63 9.91 121 288394 45385 64164832
Tuberculosis gastrointestinal 19.60 9.91 17 288498 487 64209730
Staphylococcal bacteraemia 19.56 9.91 95 288420 10260 64199957
Kidney rupture 19.46 9.91 12 288503 199 64210018
Herpes simplex oesophagitis 19.45 9.91 13 288502 249 64209968
Lichen sclerosus 19.45 9.91 22 288493 875 64209342
Nephrolithiasis 19.45 9.91 115 288400 43568 64166649
Cerebral artery stenosis 19.35 9.91 19 288496 640 64209577
Exophthalmos 19.29 9.91 29 288486 1531 64208686
Oedema 19.28 9.91 292 288223 91643 64118574
Lung neoplasm malignant 19.25 9.91 42 288473 21406 64188811
Injury 19.23 9.91 159 288356 55833 64154384
Colitis ulcerative 19.20 9.91 172 288343 22856 64187361
Dementia 19.19 9.91 40 288475 20726 64189491
Antinuclear antibody 19.18 9.91 16 288499 434 64209783
Klebsiella test positive 19.17 9.91 27 288488 1343 64208874
Hot flush 19.17 9.91 302 288213 45933 64164284
Gait inability 19.15 9.91 111 288404 42257 64167960
Bronchopneumopathy 19.12 9.91 18 288497 575 64209642
Wound evisceration 19.10 9.91 10 288505 119 64210098
Respiratory tract infection fungal 19.09 9.91 24 288491 1068 64209149
Hypoacusis 19.07 9.91 56 288459 25811 64184406
Hyperoxaluria 19.06 9.91 13 288502 258 64209959
Osteoporosis 19.04 9.91 279 288236 41801 64168416
Peliosis hepatis 18.99 9.91 9 288506 85 64210132
Hypokalaemia 18.98 9.91 408 288107 121495 64088722
Anaphylactic reaction 18.91 9.91 421 288094 68243 64141974
Ultrasound ovary abnormal 18.81 9.91 9 288506 87 64210130
CSF measles antibody positive 18.81 9.91 8 288507 57 64210160
Tendonitis 18.80 9.91 39 288476 20243 64189974
Deep vein thrombosis 18.80 9.91 344 288171 104838 64105379
Oral pruritus 18.78 9.91 31 288484 1774 64208443
Colitis microscopic 18.77 9.91 5 288510 7427 64202790
Chronic kidney disease 18.76 9.91 167 288348 57752 64152465
Neurosarcoidosis 18.75 9.91 14 288501 322 64209895
Rhesus antigen positive 18.74 9.91 10 288505 124 64210093
Obstructive airways disorder 18.74 9.91 48 288467 23137 64187080
Creatinine urine decreased 18.70 9.91 12 288503 214 64210003
Hairy cell leukaemia 18.69 9.91 8 288507 58 64210159
Abscess 18.64 9.91 149 288366 19155 64191062
Cerebral fungal infection 18.64 9.91 14 288501 325 64209892
Adenoviral hepatitis 18.63 9.91 16 288499 452 64209765
Herpes zoster meningoencephalitis 18.62 9.91 19 288496 671 64209546
Respiratory disorder 18.60 9.91 245 288270 35866 64174351
Urine oxalate increased 18.51 9.91 12 288503 218 64209999
Renal artery stenosis 18.50 9.91 41 288474 2928 64207289
Immune reconstitution inflammatory syndrome 18.49 9.91 107 288408 12363 64197854
Bacterial pyelonephritis 18.35 9.91 17 288498 532 64209685
Osmotic demyelination syndrome 18.33 9.91 25 288490 1206 64209011
Klebsiella sepsis 18.30 9.91 38 288477 2594 64207623
Peritoneal candidiasis 18.25 9.91 6 288509 18 64210199
Depressed mood 18.24 9.91 108 288407 40904 64169313
Torulopsis infection 18.20 9.91 7 288508 37 64210180
Birdshot chorioretinopathy 18.13 9.91 8 288507 63 64210154
Splenic embolism 18.12 9.91 11 288504 177 64210040
Visceral leishmaniasis 18.11 9.91 22 288493 945 64209272
Fungal test positive 18.04 9.91 22 288493 949 64209268
Temperature intolerance 18.01 9.91 79 288436 8176 64202041
Cystitis viral 18.01 9.91 18 288497 620 64209597
Scedosporium infection 17.97 9.91 25 288490 1229 64208988
Cytokine storm 17.96 9.91 21 288494 866 64209351
Renal tubular injury 17.93 9.91 24 288491 1137 64209080
B-lymphocyte count increased 17.88 9.91 10 288505 137 64210080
Tri-iodothyronine free decreased 17.85 9.91 14 288501 347 64209870
Epistaxis 17.84 9.91 320 288195 97811 64112406
Pneumocephalus 17.82 9.91 12 288503 233 64209984
Complications of transplanted liver 17.78 9.91 14 288501 349 64209868
Histoplasmosis disseminated 17.75 9.91 32 288483 1966 64208251
Hepatic infarction 17.71 9.91 20 288495 794 64209423
Diabetic ketoacidosis 17.68 9.91 71 288444 29774 64180443
Escherichia urinary tract infection 17.66 9.91 103 288412 11934 64198283
Arteriovenous fistula 17.60 9.91 21 288494 885 64209332
Amoebiasis 17.57 9.91 9 288506 102 64210115
Joint tuberculosis 17.56 9.91 10 288505 142 64210075
Granuloma skin 17.56 9.91 3 288512 6071 64204146
Bifidobacterium infection 17.55 9.91 6 288509 21 64210196
Epstein-Barr virus test positive 17.55 9.91 22 288493 976 64209241
Myelocyte percentage increased 17.55 9.91 12 288503 239 64209978
Blood sodium decreased 17.55 9.91 70 288445 29412 64180805
Metastases to bone 17.54 9.91 41 288474 20394 64189823
Delayed engraftment 17.51 9.91 12 288503 240 64209977
Sudden death 17.51 9.91 40 288475 20056 64190161
Salivary hypersecretion 17.48 9.91 17 288498 12096 64198121
Post procedural bile leak 17.42 9.91 14 288501 360 64209857
Agitation 17.41 9.91 284 288231 88083 64122134
Venoocclusive disease 17.37 9.91 48 288467 3937 64206280
Bordetella infection 17.35 9.91 9 288506 105 64210112
Monocyte percentage decreased 17.34 9.91 12 288503 244 64209973
Chorioretinitis 17.33 9.91 18 288497 649 64209568
Gonococcal infection 17.33 9.91 7 288508 43 64210174
Dysmenorrhoea 17.30 9.91 36 288479 2461 64207756
Quadriparesis 17.29 9.91 39 288476 2818 64207399
White blood cells urine 17.29 9.91 14 288501 364 64209853
Herpes simplex hepatitis 17.29 9.91 15 288500 430 64209787
Blood thyroid stimulating hormone increased 17.28 9.91 74 288441 7580 64202637
Infusion site pain 17.27 9.91 92 288423 10305 64199912
Bone marrow failure 17.23 9.91 306 288209 47646 64162571
Mycobacterial infection 17.21 9.91 40 288475 2948 64207269
Tremor 17.21 9.91 518 287997 147712 64062505
Gastrointestinal candidiasis 17.19 9.91 13 288502 305 64209912
Immunosuppression 17.12 9.91 94 288421 10652 64199565
Norovirus test positive 17.11 9.91 15 288500 436 64209781
Polychondritis 17.08 9.91 15 288500 437 64209780
Bone erosion 17.05 9.91 16 288499 11579 64198638
Renal necrosis 17.05 9.91 12 288503 251 64209966
Acne 17.04 9.91 168 288347 22913 64187304
Neuropsychiatric lupus 17.03 9.91 10 288505 151 64210066
Wolff-Parkinson-White syndrome 17.00 9.91 12 288503 252 64209965
Intestinal obstruction 16.98 9.91 94 288421 36192 64174025
Haemoperitoneum 16.91 9.91 47 288468 3868 64206349
Back disorder 16.91 9.91 12 288503 9978 64200239
Proteus infection 16.80 9.91 28 288487 1615 64208602
Blood parathyroid hormone decreased 16.73 9.91 6 288509 7360 64202857
Post-traumatic stress disorder 16.73 9.91 49 288466 4156 64206061
Capillary leak syndrome 16.71 9.91 42 288473 3255 64206962
Hyperthermia 16.68 9.91 123 288392 15427 64194790
Pyomyositis 16.67 9.91 16 288499 524 64209693
Acute respiratory failure 16.67 9.91 315 288200 49619 64160598
Melaena 16.65 9.91 156 288359 53392 64156825
Tumour lysis syndrome 16.62 9.91 146 288369 19294 64190923
Injection site extravasation 16.60 9.91 76 288439 8010 64202207
Listeria sepsis 16.57 9.91 17 288498 604 64209613
Muir-Torre syndrome 16.56 9.91 7 288508 49 64210168
Coma scale abnormal 16.56 9.91 7 288508 7767 64202450
Uterine perforation 16.55 9.91 3 288512 5817 64204400
IVth nerve paralysis 16.53 9.91 10 288505 160 64210057
Cytomegalovirus duodenitis 16.49 9.91 8 288507 80 64210137
Hypofibrinogenaemia 16.47 9.91 29 288486 1749 64208468
Intestinal ulcer 16.45 9.91 28 288487 1643 64208574
Disseminated varicella zoster virus infection 16.45 9.91 12 288503 266 64209951
Pulmonary embolism 16.37 9.91 514 288001 145842 64064375
Flatulence 16.36 9.91 93 288422 35573 64174644
Hip fracture 16.35 9.91 64 288451 27035 64183182
Hepatic artery occlusion 16.32 9.91 8 288507 82 64210135
Haematocrit decreased 16.30 9.91 339 288176 54316 64155901
Trichodysplasia spinulosa 16.28 9.91 18 288497 698 64209519
Diaphragmatic injury 16.24 9.91 9 288506 121 64210096
Intravascular haemolysis 16.20 9.91 18 288497 702 64209515
Enterococcal sepsis 16.18 9.91 35 288480 2459 64207758
Pericarditis fungal 16.15 9.91 10 288505 167 64210050
Dizziness postural 16.14 9.91 12 288503 9740 64200477
Blindness 16.13 9.91 160 288355 21859 64188358
Herpes simplex encephalitis 16.13 9.91 17 288498 624 64209593
Injection site induration 16.11 9.91 10 288505 8922 64201295
Hypertensive encephalopathy 16.09 9.91 20 288495 880 64209337
Enterococcal bacteraemia 16.07 9.91 35 288480 2470 64207747
Basal cell carcinoma 16.06 9.91 77 288438 30761 64179456
Hypoproteinaemia 16.02 9.91 42 288473 3340 64206877
Thrombotic thrombocytopenic purpura 16.01 9.91 61 288454 5923 64204294
Faeces discoloured 16.01 9.91 60 288455 25669 64184548
Passenger lymphocyte syndrome 15.99 9.91 8 288507 86 64210131
Anxiety 15.97 9.91 742 287773 201907 64008310
Second primary malignancy 15.93 9.91 19 288496 12318 64197899
Sodium retention 15.83 9.91 8 288507 88 64210129
Adrenal atrophy 15.77 9.91 7 288508 56 64210161
Cutaneous nocardiosis 15.75 9.91 10 288505 175 64210042
Mean platelet volume decreased 15.74 9.91 28 288487 1703 64208514
Hepatocellular carcinoma 15.72 9.91 9 288506 8394 64201823
Tachypnoea 15.72 9.91 185 288330 26386 64183831
Vaginal haemorrhage 15.67 9.91 40 288475 19304 64190913
Dysarthria 15.63 9.91 180 288335 59226 64150991
Glucose urine present 15.62 9.91 27 288488 1605 64208612
Haemorrhoids 15.58 9.91 55 288460 23946 64186271
Stent placement 15.57 9.91 3 288512 5568 64204649
Pulmonary tuberculosis 15.56 9.91 69 288446 7175 64203042
Shock 15.56 9.91 249 288266 37991 64172226
Diffuse mesangial sclerosis 15.55 9.91 6 288509 32 64210185
Disseminated aspergillosis 15.54 9.91 17 288498 651 64209566
Abdominal compartment syndrome 15.50 9.91 25 288490 1403 64208814
Hepatic necrosis 15.48 9.91 77 288438 8396 64201821
Thyrotoxic periodic paralysis 15.44 9.91 8 288507 93 64210124
Hemianopia 15.44 9.91 26 288489 1513 64208704
Middle insomnia 15.41 9.91 21 288494 12856 64197361
Cold type haemolytic anaemia 15.32 9.91 12 288503 297 64209920
Perineal ulceration 15.26 9.91 7 288508 61 64210156
Herpes simplex meningoencephalitis 15.26 9.91 7 288508 61 64210156
Gastropleural fistula 15.26 9.91 7 288508 61 64210156
Multi-organ disorder 15.25 9.91 32 288483 2201 64208016
Aspiration 15.21 9.91 33 288482 16852 64193365
Uraemic encephalopathy 15.16 9.91 15 288500 510 64209707
Ageusia 15.10 9.91 24 288491 13789 64196428
Splenic necrosis 15.08 9.91 8 288507 98 64210119
Atrioventricular block 14.99 9.91 19 288496 11996 64198221
Post procedural urine leak 14.98 9.91 9 288506 142 64210075
Gastrointestinal haemorrhage 14.96 9.91 464 288051 131848 64078369
Erythema infectiosum 14.94 9.91 10 288505 192 64210025
Throat tightness 14.94 9.91 164 288351 22996 64187221
Meningitis exserohilum 14.90 9.91 4 288511 4 64210213
Haemorrhagic varicella syndrome 14.90 9.91 4 288511 4 64210213
Accelerated idioventricular rhythm 14.87 9.91 9 288506 144 64210073
Vesicoureteric reflux 14.87 9.91 8 288507 101 64210116
Polyglandular disorder 14.83 9.91 6 288509 37 64210180
Cytomegalovirus nephritis 14.82 9.91 9 288506 145 64210072
Paraplegia 14.79 9.91 49 288466 4441 64205776
Thyroid stimulating immunoglobulin 14.78 9.91 7 288508 66 64210151
Sinus node dysfunction 14.78 9.91 6 288509 6822 64203395
Chronic obstructive pulmonary disease 14.78 9.91 226 288289 70822 64139395
Transaminases increased 14.78 9.91 281 288234 44313 64165904
Meningitis chemical 14.77 9.91 10 288505 196 64210021
Blood 1,25-dihydroxycholecalciferol increased 14.74 9.91 5 288510 17 64210200
Aspergillus test positive 14.74 9.91 17 288498 691 64209526
Swollen joint count increased 14.73 9.91 8 288507 7681 64202536
Red blood cell elliptocytes present 14.71 9.91 9 288506 147 64210070
Marrow hyperplasia 14.71 9.91 24 288491 1360 64208857
Drug level decreased 14.71 9.91 95 288420 11408 64198809
Nocturia 14.63 9.91 17 288498 11148 64199069
Bacterial vulvovaginitis 14.62 9.91 14 288501 457 64209760
Beta 2 microglobulin increased 14.59 9.91 12 288503 319 64209898
Familial periodic paralysis 14.55 9.91 9 288506 150 64210067
Hypoxia 14.53 9.91 506 288009 87643 64122574
Mucosal ulceration 14.51 9.91 27 288488 1700 64208517
Acne fulminans 14.50 9.91 9 288506 151 64210066
Rash 14.50 9.91 1813 286702 456736 63753481
Arrhythmia 14.49 9.91 159 288356 52785 64157432
Encephalitis brain stem 14.46 9.91 10 288505 203 64210014
Amnesia 14.42 9.91 142 288373 48127 64162090
Embolic stroke 14.36 9.91 6 288509 6705 64203512
Biliary anastomosis complication 14.35 9.91 9 288506 154 64210063
Oral candidiasis 14.35 9.91 163 288352 23049 64187168
Polymenorrhoea 14.34 9.91 19 288496 891 64209326
Pleural mass 14.34 9.91 7 288508 71 64210146
Disseminated blastomycosis 14.34 9.91 8 288507 109 64210108
Haematopoietic stem cell mobilisation 14.34 9.91 10 288505 206 64210011
Transient hypogammaglobulinaemia of infancy 14.32 9.91 6 288509 41 64210176
Radiotherapy to brain 14.32 9.91 6 288509 41 64210176
Chimerism 14.29 9.91 11 288504 265 64209952
Magnesium deficiency 14.29 9.91 15 288500 548 64209669
Fracture 14.27 9.91 40 288475 18715 64191502
Atrial flutter 14.26 9.91 42 288473 19338 64190879
Haemoglobinuria 14.26 9.91 17 288498 716 64209501
Lung disorder 14.23 9.91 364 288151 60336 64149881
Intra-abdominal haemorrhage 14.19 9.91 45 288470 3986 64206231
Cutaneous malacoplakia 14.17 9.91 7 288508 73 64210144
Campylobacter gastroenteritis 14.16 9.91 21 288494 1095 64209122
Chronic graft versus host disease in liver 14.11 9.91 15 288500 556 64209661
Aspergilloma 14.10 9.91 14 288501 478 64209739
Femoral neck fracture 14.10 9.91 11 288504 8713 64201504
Acinetobacter test positive 14.05 9.91 10 288505 213 64210004
Leishmaniasis 14.04 9.91 12 288503 337 64209880
Myelocyte present 14.02 9.91 4 288511 6 64210211
Parathyroid hyperplasia 14 9.91 9 288506 161 64210056
Pneumonia lipoid 14 9.91 9 288506 161 64210056
Creatinine urine increased 13.92 9.91 13 288502 411 64209806
Hepatic cancer 13.91 9.91 8 288507 7440 64202777
Tricuspid valve incompetence 13.90 9.91 35 288480 16968 64193249
Cyanosis 13.89 9.91 156 288359 21999 64188218
Encephalitis fungal 13.86 9.91 9 288506 164 64210053
Mycobacterium kansasii infection 13.85 9.91 11 288504 278 64209939
Fungal endocarditis 13.82 9.91 14 288501 490 64209727
Arterial rupture 13.80 9.91 17 288498 741 64209476
Limbic encephalitis 13.78 9.91 16 288499 655 64209562
Liver function test abnormal 13.74 9.91 185 288330 59216 64151001
Neurological symptom 13.71 9.91 64 288451 6800 64203417
Abnormal behaviour 13.68 9.91 91 288424 33531 64176686
Lip swelling 13.68 9.91 85 288430 31822 64178395
Pancreatitis 13.66 9.91 186 288329 59421 64150796
Microangiopathic haemolytic anaemia 13.65 9.91 23 288492 1339 64208878
Central nervous system vasculitis 13.63 9.91 21 288494 1133 64209084
Thrombosis in device 13.62 9.91 3 288512 5068 64205149
Arthritis fungal 13.61 9.91 8 288507 121 64210096
Allergy test positive 13.61 9.91 13 288502 423 64209794
Spinal stenosis 13.59 9.91 26 288489 13905 64196312
Ovarian fibroma 13.54 9.91 7 288508 81 64210136
Cardiovascular disorder 13.52 9.91 32 288483 15849 64194368
Inflammatory marker increased 13.51 9.91 74 288441 8377 64201840
Muscle rigidity 13.49 9.91 37 288478 17436 64192781
Oral fungal infection 13.47 9.91 37 288478 3024 64207193
Rheumatic fever 13.46 9.91 13 288502 9281 64200936
Angioedema 13.43 9.91 195 288320 61626 64148591
Allergy to plants 13.41 9.91 15 288500 589 64209628
Infertility 13.41 9.91 14 288501 508 64209709
Wound infection bacterial 13.41 9.91 17 288498 763 64209454
Injection site discolouration 13.39 9.91 7 288508 6868 64203349
Expired product administered 13.39 9.91 5 288510 5982 64204235
Muscle twitching 13.39 9.91 42 288473 18956 64191261
Exostosis 13.35 9.91 19 288496 11419 64198798
Activated partial thromboplastin time shortened 13.32 9.91 17 288498 768 64209449
Disseminated trichosporonosis 13.32 9.91 7 288508 84 64210133
Ophthalmoplegia 13.25 9.91 34 288481 2668 64207549
Lupus myocarditis 13.25 9.91 7 288508 85 64210132
H3N2 influenza 13.24 9.91 3 288512 0 64210217
Interstitial lung disease 13.24 9.91 549 287966 97183 64113034
Irritability 13.24 9.91 103 288412 36643 64173574
Malignant catatonia 13.23 9.91 12 288503 365 64209852
Amoebic dysentery 13.22 9.91 5 288510 25 64210192
Ependymoma 13.21 9.91 6 288509 51 64210166
Scleritis 13.20 9.91 36 288479 2930 64207287
Cerebellar stroke 13.19 9.91 13 288502 440 64209777
Anastomotic haemorrhage 13.17 9.91 10 288505 236 64209981
Cholecystectomy 13.14 9.91 10 288505 8022 64202195
Meningoencephalitis bacterial 13.13 9.91 9 288506 180 64210037
Ulcer 13.13 9.91 159 288356 22831 64187386
Hepatosplenomegaly 13.11 9.91 53 288462 5290 64204927
Skin fissures 13.11 9.91 85 288430 10221 64199996
Hypocomplementaemia 13.09 9.91 9 288506 181 64210036
Oral discomfort 13.08 9.91 11 288504 8395 64201822
Nephrogenic systemic fibrosis 13.05 9.91 5 288510 5887 64204330
Diffuse large B-cell lymphoma stage III 13.04 9.91 7 288508 88 64210129
Thyroid stimulating immunoglobulin increased 13.04 9.91 7 288508 88 64210129
Reticulocytopenia 13.00 9.91 9 288506 183 64210034
Muscle abscess 13.00 9.91 18 288497 881 64209336
Skin necrosis 12.98 9.91 109 288406 14220 64195997
Organising pneumonia 12.97 9.91 77 288438 8978 64201239
Breast cancer metastatic 12.96 9.91 8 288507 7161 64203056
Colitis 12.93 9.91 349 288166 58325 64151892
Arteritis coronary 12.91 9.91 6 288509 54 64210163
Infected varicose vein 12.91 9.91 5 288510 27 64210190
Body height decreased 12.89 9.91 9 288506 7545 64202672
Graft infection 12.88 9.91 15 288500 616 64209601
Abscess fungal 12.85 9.91 10 288505 245 64209972
Retching 12.78 9.91 31 288484 15225 64194992
Alcohol abuse 12.77 9.91 3 288512 4849 64205368
Granulomatous liver disease 12.73 9.91 21 288494 1201 64209016
Joint injury 12.72 9.91 56 288459 22891 64187326
Geotrichum infection 12.71 9.91 18 288497 900 64209317
Gastroduodenal ulcer 12.70 9.91 13 288502 461 64209756
Eye luxation 12.69 9.91 4 288511 10 64210207
Hepatitis A 12.67 9.91 17 288498 807 64209410
Encephalomyelitis 12.67 9.91 9 288506 191 64210026
Diabetic macroangiopathy 12.65 9.91 8 288507 139 64210078
Pneumonia influenzal 12.65 9.91 32 288483 2490 64207727
Pneumonia necrotising 12.63 9.91 18 288497 905 64209312
Viral test positive 12.63 9.91 12 288503 388 64209829
CD8 lymphocytes decreased 12.61 9.91 10 288505 252 64209965
Schizophrenia 12.59 9.91 19 288496 11149 64199068
Delusion 12.57 9.91 40 288475 17974 64192243
Diverticulum 12.56 9.91 25 288490 13173 64197044
Lactic acidosis 12.55 9.91 196 288319 61214 64149003
Viral load abnormal 12.54 9.91 6 288509 58 64210159
Angina pectoris 12.49 9.91 135 288380 44946 64165271
Fibromyalgia 12.48 9.91 101 288414 35630 64174587
Inadequate aseptic technique in use of product 12.44 9.91 7 288508 97 64210120
Drug tolerance decreased 12.39 9.91 8 288507 6990 64203227
Brain herniation 12.39 9.91 60 288455 6473 64203744
Meningomyelitis herpes 12.37 9.91 6 288509 60 64210157
Paranoia 12.35 9.91 35 288480 16317 64193900
Tongue fungal infection 12.34 9.91 5 288510 31 64210186
Coronary arterial stent insertion 12.32 9.91 5 288510 5687 64204530
Myelocyte count increased 12.32 9.91 16 288499 736 64209481
Trichophytosis 12.31 9.91 11 288504 328 64209889
Pulmonary necrosis 12.25 9.91 13 288502 481 64209736
Blastomycosis 12.25 9.91 13 288502 481 64209736
Paraparesis 12.24 9.91 39 288476 3463 64206754
JC polyomavirus test positive 12.23 9.91 21 288494 1241 64208976
Sputum discoloured 12.21 9.91 40 288475 17816 64192401
Skin test positive 12.21 9.91 19 288496 1034 64209183
Hyperammonaemia 12.18 9.91 81 288434 9823 64200394
Endocrine ophthalmopathy 12.16 9.91 12 288503 407 64209810
Application site erythema 12.14 9.91 3 288512 4686 64205531
Hepatic vein stenosis 12.11 9.91 6 288509 63 64210154
Cytomegalovirus gastritis 12.11 9.91 12 288503 409 64209808
Respiratory gas exchange disorder 12.10 9.91 16 288499 749 64209468
Infusion site discomfort 12.08 9.91 16 288499 750 64209467
Eosinophil count increased 12.07 9.91 106 288409 14006 64196211
Foetal growth restriction 12.06 9.91 25 288490 1705 64208512
Hypercapnia 12.05 9.91 67 288448 7627 64202590
Alternaria infection 12.04 9.91 14 288501 574 64209643
Vessel puncture site bruise 12.04 9.91 12 288503 412 64209805
Pseudopolyposis 12.03 9.91 6 288509 64 64210153
Disseminated cytomegaloviral infection 12.01 9.91 12 288503 413 64209804
Hallucination, visual 12.01 9.91 74 288441 27760 64182457
Cerebral venous sinus thrombosis 11.99 9.91 26 288489 1829 64208388
Multiple fractures 11.99 9.91 6 288509 6034 64204183
Skin cancer 11.99 9.91 22 288493 11952 64198265
Interleukin level increased 11.99 9.91 12 288503 414 64209803
Internal haemorrhage 11.97 9.91 10 288505 7657 64202560
Bilirubin conjugated increased 11.97 9.91 49 288466 4919 64205298
Lower gastrointestinal haemorrhage 11.94 9.91 28 288487 13911 64196306
Arterial spasm 11.94 9.91 8 288507 154 64210063
Impaired work ability 11.92 9.91 32 288483 15187 64195030
Cytomegalovirus gastroenteritis 11.92 9.91 12 288503 417 64209800
Acute pulmonary oedema 11.90 9.91 98 288417 12711 64197506
Butterfly rash 11.90 9.91 20 288495 1162 64209055
Meningitis listeria 11.89 9.91 16 288499 762 64209455
Varicella 11.86 9.91 32 288483 2589 64207628
Epidural lipomatosis 11.85 9.91 17 288498 860 64209357
Hepatic cyst infection 11.85 9.91 8 288507 156 64210061
Adjusted calcium decreased 11.85 9.91 8 288507 156 64210061
Urogenital disorder 11.79 9.91 6 288509 67 64210150
Drug eruption 11.79 9.91 104 288411 36032 64174185
Meningoencephalitis herpetic 11.75 9.91 25 288490 1736 64208481
Hepatitis C 11.74 9.91 87 288428 10928 64199289
Encephalitis viral 11.73 9.91 30 288485 2350 64207867
Stridor 11.68 9.91 48 288467 4826 64205391
Large intestine polyp 11.68 9.91 19 288496 10818 64199399
Viral myocarditis 11.66 9.91 12 288503 428 64209789
Night sweats 11.64 9.91 104 288411 35942 64174275
Cryptococcal cutaneous infection 11.63 9.91 8 288507 161 64210056
Acute myeloid leukaemia recurrent 11.61 9.91 33 288482 2751 64207466
Gastric haemorrhage 11.61 9.91 27 288488 13454 64196763
Electrocardiogram abnormal 11.61 9.91 27 288488 13454 64196763
Complication associated with device 11.59 9.91 32 288483 15048 64195169
Diarrhoea haemorrhagic 11.58 9.91 88 288427 11139 64199078
Jaundice cholestatic 11.57 9.91 13 288502 8657 64201560
Hepatic haemorrhage 11.57 9.91 17 288498 879 64209338
Meniscus injury 11.53 9.91 6 288509 5901 64204316
Glomerulonephritis membranoproliferative 11.51 9.91 13 288502 516 64209701
Faecaloma 11.51 9.91 16 288499 9712 64200505
Optic nerve compression 11.49 9.91 4 288511 15 64210202
Thrombocytopenic purpura 11.44 9.91 28 288487 2134 64208083
International normalised ratio abnormal 11.44 9.91 4 288511 4984 64205233
Glomerulonephropathy 11.43 9.91 10 288505 290 64209927
Breast abscess 11.43 9.91 19 288496 1094 64209123
Dengue fever 11.42 9.91 16 288499 792 64209425
Eye infection fungal 11.42 9.91 12 288503 439 64209778
Coccidioidomycosis 11.41 9.91 19 288496 1095 64209122
Chronic papillomatous dermatitis 11.35 9.91 6 288509 73 64210144
Granulocyte percentage 11.35 9.91 6 288509 73 64210144
Glomerulonephritis membranous 11.32 9.91 21 288494 1319 64208898
Abdominal abscess 11.32 9.91 57 288458 6247 64203970
Haptoglobin decreased 11.29 9.91 20 288495 1212 64209005
Carotid artery insufficiency 11.29 9.91 4 288511 16 64210201
Human herpes virus 8 test positive 11.26 9.91 5 288510 40 64210177
Product use issue 11.25 9.91 559 287956 151156 64059061
Chronic hepatitis C 11.24 9.91 13 288502 530 64209687
Papilloma viral infection 11.21 9.91 22 288493 1442 64208775
Urinary fistula 11.20 9.91 6 288509 75 64210142
Capnocytophaga infection 11.20 9.91 6 288509 75 64210142
Eye pruritus 11.19 9.91 25 288490 12634 64197583
Nephropathy 11.18 9.91 70 288445 8316 64201901
Catheter site necrosis 11.18 9.91 3 288512 3 64210214
Blood catecholamines abnormal 11.18 9.91 3 288512 3 64210214
Osteoarthropathy 11.18 9.91 3 288512 3 64210214
Central venous pressure increased 11.15 9.91 7 288508 120 64210097
Gastrointestinal scarring 11.14 9.91 9 288506 233 64209984
Paraesthesia ear 11.14 9.91 8 288507 173 64210044
Abnormal loss of weight 11.13 9.91 10 288505 7390 64202827
Hepatic steatosis 11.13 9.91 87 288428 30920 64179297
Ischaemic stroke 11.12 9.91 80 288435 28955 64181262
Palmar erythema 11.09 9.91 24 288491 1686 64208531
Cavernous sinus thrombosis 11.09 9.91 10 288505 302 64209915
Type 2 diabetes mellitus 11.06 9.91 98 288417 33922 64176295
Asphyxia 11.05 9.91 16 288499 9550 64200667
Larynx irritation 11.05 9.91 7 288508 122 64210095
Seizure 11.05 9.91 622 287893 166270 64043947
Gastrointestinal oedema 11.02 9.91 29 288486 2311 64207906
Pneumonia adenoviral 10.98 9.91 8 288507 177 64210040
Generalised oedema 10.96 9.91 142 288373 20711 64189506
Aortic pseudoaneurysm 10.95 9.91 5 288510 43 64210174
Acid base balance abnormal 10.95 9.91 10 288505 307 64209910
Coronary artery aneurysm 10.95 9.91 7 288508 124 64210093
Dry throat 10.94 9.91 56 288459 6176 64204041
Dysstasia 10.94 9.91 60 288455 23155 64187062
Vein collapse 10.93 9.91 14 288501 635 64209582
Subcutaneous emphysema 10.92 9.91 23 288492 1586 64208631
Exercise tolerance decreased 10.92 9.91 11 288504 7699 64202518
Acute endocarditis 10.92 9.91 4 288511 18 64210199
Coombs direct test positive 10.91 9.91 11 288504 383 64209834
Excessive skin 10.90 9.91 7 288508 125 64210092
Liver function test 10.90 9.91 7 288508 125 64210092
Thyroxine free decreased 10.90 9.91 16 288499 827 64209390
Oropharyngeal pain 10.88 9.91 494 288021 88373 64121844
Adult T-cell lymphoma/leukaemia 10.87 9.91 10 288505 310 64209907
Retinal scar 10.86 9.91 11 288504 385 64209832
Pneumonia aspiration 10.86 9.91 193 288322 59078 64151139
Anaphylactoid reaction 10.84 9.91 46 288469 4692 64205525
Obsessive-compulsive disorder 10.82 9.91 4 288511 4814 64205403
Creatinine renal clearance decreased 10.79 9.91 31 288484 14390 64195827
Tracheobronchitis 10.79 9.91 24 288491 1718 64208499
Necrosis 10.77 9.91 68 288447 8103 64202114
Double stranded DNA antibody positive 10.77 9.91 11 288504 389 64209828
Bone infarction 10.77 9.91 11 288504 389 64209828
Urinoma 10.75 9.91 8 288507 183 64210034
Metamyelocyte percentage increased 10.75 9.91 4 288511 19 64210198
Libido decreased 10.69 9.91 4 288511 4780 64205437
Gastritis fungal 10.68 9.91 8 288507 185 64210032
Interleukin-2 receptor increased 10.68 9.91 8 288507 185 64210032
Eosinopenia 10.67 9.91 5 288510 46 64210171
Tubulointerstitial nephritis 10.67 9.91 196 288319 30713 64179504
Eye infection toxoplasmal 10.65 9.91 12 288503 475 64209742
Dermatophytosis 10.63 9.91 11 288504 395 64209822
Venoocclusive liver disease 10.62 9.91 79 288436 9936 64200281
Pre-existing condition improved 10.61 9.91 4 288511 4758 64205459
Vasculitis necrotising 10.61 9.91 18 288497 1054 64209163
Atrioventricular block second degree 10.60 9.91 8 288507 6446 64203771
Clostridium colitis 10.60 9.91 30 288485 2495 64207722
Glucose-6-phosphate dehydrogenase deficiency 10.58 9.91 10 288505 321 64209896
Urine uric acid increased 10.57 9.91 5 288510 47 64210170
Urine bilirubin increased 10.57 9.91 7 288508 132 64210085
Unmasking of previously unidentified disease 10.55 9.91 23 288492 1624 64208593
Therapy change 10.54 9.91 8 288507 6426 64203791
Adenomatous polyposis coli 10.53 9.91 8 288507 189 64210028
Endocarditis 10.53 9.91 75 288440 9303 64200914
Pulse pressure increased 10.52 9.91 7 288508 133 64210084
Bulbar palsy 10.52 9.91 9 288506 253 64209964
Carotid artery stenosis 10.50 9.91 12 288503 7929 64202288
Ureteral necrosis 10.49 9.91 6 288509 86 64210131
Gynaecomastia 10.49 9.91 7 288508 6009 64204208
Groin pain 10.48 9.91 22 288493 11371 64198846
Bone disorder 10.48 9.91 39 288476 16720 64193497
Oral bacterial infection 10.48 9.91 5 288510 48 64210169
Megacolon 10.48 9.91 34 288481 3048 64207169
Nephritis 10.45 9.91 38 288477 3608 64206609
Fungal sepsis 10.45 9.91 23 288492 1635 64208582
Coronary artery dilatation 10.42 9.91 4 288511 21 64210196
Meningitis aseptic 10.42 9.91 52 288463 5678 64204539
Gastrointestinal perforation 10.42 9.91 50 288465 5374 64204843
Blood urea increased 10.41 9.91 265 288250 43888 64166329
Myocarditis infectious 10.39 9.91 5 288510 49 64210168
Liver abscess 10.38 9.91 49 288466 5231 64204986
Tuberous sclerosis complex 10.37 9.91 6 288509 88 64210129
Immune-mediated lung disease 10.36 9.91 19 288496 1183 64209034
Cardiac operation 10.34 9.91 3 288512 4211 64206006
Hypomagnesaemia 10.32 9.91 112 288403 37264 64172953
Cytomegalovirus test 10.31 9.91 5 288510 50 64210167
Dysaesthesia 10.29 9.91 47 288468 4948 64205269
Hiatus hernia 10.29 9.91 50 288465 19907 64190310
Hepatitis toxic 10.29 9.91 43 288472 4357 64205860
Erosive duodenitis 10.26 9.91 23 288492 1655 64208562
Necrotising oesophagitis 10.26 9.91 14 288501 676 64209541
Wheezing 10.26 9.91 278 288237 80301 64129916
Device related sepsis 10.25 9.91 48 288467 5107 64205110
Ventricular extrasystoles 10.19 9.91 42 288473 17487 64192730
Synovial fluid analysis 10.15 9.91 22 288493 1547 64208670
Toxic neuropathy 10.13 9.91 15 288500 781 64209436
Central obesity 10.11 9.91 21 288494 1434 64208783
Hepatic artery stenosis 10.09 9.91 7 288508 143 64210074
Growth hormone deficiency 10.09 9.91 10 288505 341 64209876
Haemostasis 10.06 9.91 9 288506 269 64209948
Pelvic fracture 10.06 9.91 20 288495 10543 64199674
Viral vasculitis 10.04 9.91 7 288508 144 64210073
Hepatitis viral 10.04 9.91 16 288499 889 64209328
Acarodermatitis 10.03 9.91 19 288496 1213 64209004
Tularaemia 10.03 9.91 6 288509 94 64210123
Disability 9.99 9.91 25 288490 12147 64198070
Castleman's disease 9.98 9.91 4 288511 24 64210193
Osseous cryptococcosis 9.97 9.91 3 288512 6 64210211
Haptoglobin abnormal 9.97 9.91 3 288512 6 64210211
Thymoma 9.96 9.91 7 288508 146 64210071
Renal tubular disorder 9.96 9.91 53 288462 5934 64204283
Mitral valve incompetence 9.96 9.91 70 288445 25468 64184749
Cardiac pacemaker insertion 9.96 9.91 5 288510 5018 64205199
Tooth loss 9.94 9.91 8 288507 6239 64203978
Mucocutaneous leishmaniasis 9.94 9.91 11 288504 427 64209790
Acute lymphocytic leukaemia recurrent 9.93 9.91 40 288475 3986 64206231
Biopsy lymph gland 9.92 9.91 6 288509 96 64210121
Joint effusion 9.92 9.91 98 288417 13375 64196842
Restlessness 9.91 9.91 122 288393 39663 64170554

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
FDA MoA N0000175450 Corticosteroid Hormone Receptor Agonists
FDA EPC N0000175576 Corticosteroid
MeSH PA D000893 Anti-Inflammatory Agents
MeSH PA D000932 Antiemetics
MeSH PA D002491 Central Nervous System Agents
MeSH PA D005765 Gastrointestinal Agents
MeSH PA D005938 Glucocorticoids
MeSH PA D006728 Hormones
MeSH PA D018696 Neuroprotective Agents
MeSH PA D018373 Peripheral Nervous System Agents
MeSH PA D020011 Protective Agents
MeSH PA D000970 Antineoplastic Agents
MeSH PA D018931 Antineoplastic Agents, Hormonal
CHEBI has role CHEBI:35472 anti-inflammatory drugs
CHEBI has role CHEBI:35703 Xenobiotic
CHEBI has role CHEBI:37962 adrenergic agents
CHEBI has role CHEBI:50919 antiemetico
CHEBI has role CHEBI:63726 neuroprotective agents
CHEBI has role CHEBI:78298 environmental contaminants

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Nephrotic syndrome indication 52254009 DOID:1184




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.23 acidic
pKa2 12.63 acidic
pKa3 13.35 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Glucocorticoid receptor Nuclear hormone receptor AGONIST CHEMBL CHEMBL

External reference:

IDSource
4018069 VUID
N0000179635 NUI
D00751 KEGG_DRUG
2375-03-3 SECONDARY_CAS_RN
4018068 VANDF
4018069 VANDF
C0025819 UMLSCUI
CHEBI:135765 CHEBI
CHEBI:6888 CHEBI
CHEMBL1201265 ChEMBL_ID
CHEMBL1201081 ChEMBL_ID
DB14644 DRUGBANK_ID
23680530 PUBCHEM_CID
6741 PUBCHEM_CID
DB00959 DRUGBANK_ID
203189 RXNORM
1041 MMSL
4854 MMSL
5093 MMSL
5095 MMSL
d00293 MMSL
002160 NDDF
002162 NDDF
005280 NDDF
116593003 SNOMEDCT_US
27242001 SNOMEDCT_US
412248005 SNOMEDCT_US
734654003 SNOMEDCT_US
D008776 MESH_DESCRIPTOR_UI
C0025815 UMLSCUI
D008775 MESH_DESCRIPTOR_UI
5GMR90S4KN UNII
732 INN_ID

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0003 INJECTION, POWDER, FOR SOLUTION 500 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0018 INJECTION, POWDER, FOR SOLUTION 1 g INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0039 INJECTION, POWDER, FOR SOLUTION 40 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0039 INJECTION, POWDER, FOR SOLUTION 40 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0047 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0047 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0698 INJECTION, POWDER, FOR SOLUTION 1 g INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0698 INJECTION, POWDER, FOR SOLUTION 1 g INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0758 INJECTION, POWDER, FOR SOLUTION 500 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 0009-0850 INJECTION, POWDER, FOR SOLUTION 2 g INTRAVENOUS NDA 22 sections
Methylprednisolone Sodium Succinate HUMAN PRESCRIPTION DRUG LABEL 1 0143-9850 INJECTION, POWDER, FOR SOLUTION 500 mg INTRAMUSCULAR ANDA 22 sections
Methylprednisolone Sodium Succinate HUMAN PRESCRIPTION DRUG LABEL 1 0143-9851 INJECTION, POWDER, FOR SOLUTION 1 g INTRAMUSCULAR ANDA 22 sections
Solu-Medrol HUMAN PRESCRIPTION DRUG LABEL 1 0404-9957 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAVENOUS NDA 13 sections
Solu-Medrol HUMAN PRESCRIPTION DRUG LABEL 1 0404-9958 INJECTION, POWDER, FOR SOLUTION 40 mg INTRAVENOUS NDA 13 sections
Methylprednisolone sodium succinate HUMAN PRESCRIPTION DRUG LABEL 1 43598-127 INJECTION 40 mg INTRAVENOUS ANDA 19 sections
Methylprednisolone sodium succinate HUMAN PRESCRIPTION DRUG LABEL 1 43598-128 INJECTION 500 mg INTRAVENOUS ANDA 19 sections
Methylprednisolone sodium succinate HUMAN PRESCRIPTION DRUG LABEL 1 43598-129 INJECTION 125 mg INTRAVENOUS ANDA 19 sections
Methylprednisolone sodium succinate HUMAN PRESCRIPTION DRUG LABEL 1 43598-130 INJECTION 1 g INTRAVENOUS ANDA 19 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 50090-0271 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 50090-2253 INJECTION, POWDER, FOR SOLUTION 40 mg INTRAVENOUS NDA 22 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 51662-1263 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAMUSCULAR NDA 13 sections
SOLU-MEDROL HUMAN PRESCRIPTION DRUG LABEL 1 51662-1264 INJECTION, POWDER, FOR SOLUTION 40 mg INTRAMUSCULAR NDA 13 sections
SOLU-MEDROL(R) METHYLPREDNISOLONE SODIUM SUCCINAT HUMAN PRESCRIPTION DRUG LABEL 1 51662-1483 INJECTION, POWDER, FOR SOLUTION 500 mg INTRAMUSCULAR NDA 13 sections
Solu-Medrol HUMAN PRESCRIPTION DRUG LABEL 1 52584-039 INJECTION, POWDER, FOR SOLUTION 40 mg INTRAVENOUS NDA 13 sections
Solu-Medrol HUMAN PRESCRIPTION DRUG LABEL 1 52584-047 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAVENOUS NDA 14 sections
Solu-Medrol HUMAN PRESCRIPTION DRUG LABEL 1 52584-047 INJECTION, POWDER, FOR SOLUTION 125 mg INTRAVENOUS NDA 14 sections
Methylprednisolone Sodium Succinate Human Prescription Drug Label 1 55150-262 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 40 mg INTRAMUSCULAR ANDA 20 sections
Methylprednisolone Sodium Succinate Human Prescription Drug Label 1 55150-263 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 125 mg INTRAMUSCULAR ANDA 20 sections
Methylprednisolone Sodium Succinate Human Prescription Drug Label 1 55150-264 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 500 mg INTRAMUSCULAR ANDA 20 sections
Methylprednisolone Sodium Succinate Human Prescription Drug Label 1 55150-265 INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION 2 g INTRAMUSCULAR ANDA 20 sections