Stem definition | Drug id | CAS RN |
---|---|---|
quaternary ammonium compounds | 1736 | 5818-17-7 |
Dose | Unit | Route |
---|---|---|
0.15 | g | O |
None
Date | Agency | Company | Orphan |
---|---|---|---|
July 3, 1951 | FDA | SHIRE |
None
None
None
None
Source | Code | Description |
---|---|---|
ATC | A03AB07 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS Synthetic anticholinergics, quaternary ammonium compounds |
MeSH PA | D018678 | Cholinergic Agents |
MeSH PA | D018680 | Cholinergic Antagonists |
MeSH PA | D018727 | Muscarinic Antagonists |
MeSH PA | D018377 | Neurotransmitter Agents |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Peptic ulcer | indication | 13200003 | DOID:750 |
Urinary incontinence | indication | 165232002 | |
Gastric ulcer | indication | 397825006 | DOID:10808 |
Irritable bowel syndrome | off-label use | 10743008 | DOID:9778 |
None
None
None
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Muscarinic acetylcholine receptor | GPCR | ANTAGONIST | KEGG DRUG | KEGG DRUG |
ID | Source |
---|---|
4019823 | VUID |
N0000147912 | NUI |
4018127 | VANDF |
4019823 | VANDF |
C0025624 | UMLSCUI |
CHEBI:6817 | CHEBI |
CHEMBL1201264 | ChEMBL_ID |
D00721 | KEGG_DRUG |
CHEMBL1200988 | ChEMBL_ID |
DB00940 | DRUGBANK_ID |
53-46-3 | SECONDARY_CAS_RN |
4097 | PUBCHEM_CID |
6821 | RXNORM |
001731 | NDDF |
004692 | NDDF |
21175009 | SNOMEDCT_US |
2796008 | SNOMEDCT_US |
D000077771 | MESH_DESCRIPTOR_UI |
1878 | INN_ID |
36EI79TX7I | UNII |
None