meprednisone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
prednisone and prednisolone derivatives 1702 1247-42-3

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • meprednisone
  • betalone
  • betanisona
  • bitanisone
  • methylprednisone
  • Molecular weight: 372.46
  • Formula: C22H28O5
  • CLOGP: 2.18
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 2
  • TPSA: 91.67
  • ALOGS: -3.72
  • ROTB: 2
  • Status: OFM
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Jan. 26, 1978 FDA SCHERING

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC H02AB15 SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
CORTICOSTEROIDS FOR SYSTEMIC USE
CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
Glucocorticoids

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 12.47 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Glucocorticoid receptor Nuclear hormone receptor AGONIST CHEMBL CHEMBL

External reference:

IDSource
D06673 KEGG_DRUG
C0065967 UMLSCUI
CHEBI:135573 CHEBI
CHEMBL1201148 ChEMBL_ID
DB09383 DRUGBANK_ID
C008352 MESH_SUPPLEMENTAL_RECORD_UI
5284587 PUBCHEM_CID
1967 INN_ID
67U96J8P35 UNII
DB12952 DRUGBANK_ID
29523 RXNORM
002178 NDDF
116603004 SNOMEDCT_US
61181002 SNOMEDCT_US

Pharmaceutical products:

None