mafenide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
anti-infectives, sulfonamides 1624 138-39-6

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • mafenide
  • 4-(Aminosulfonyl)benzylamine
  • 4-Homosulfanilamide
  • 4-Sulfamoylbenzylamine
  • ambamide
  • benzamsulfonamide
  • homosulfanilamide
  • malfamin
  • maphenid
  • maphenide
  • p-Sulfamoylbenzylamine
  • mafenide acetate
  • m,afenide hydrochloride
  • m,afenide HCl
A sulfonamide that inhibits the enzyme CARBONIC ANHYDRASE and is used as a topical anti-bacterial agent, especially in burn therapy.
  • Molecular weight: 186.23
  • Formula: C7H10N2O2S
  • CLOGP: -0.74
  • LIPINSKI: 0
  • HAC: 4
  • HDO: 2
  • TPSA: 86.18
  • ALOGS: -1.56
  • ROTB: 2
  • Status: OFP
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

External reference:

Pharmaceutical products:

mafenide