Molfile
Inchi
Smiles
Synonyms:
-
lopinavir
-
aluviran
-
koletra
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An HIV protease inhibitor used in a fixed-dose combination with RITONAVIR. It is also an inhibitor of CYTOCHROME P-450 CYP3A. There was some evidence of in vitro activity against SARS-CoV-2, but no clinical trial data was found to support use in the treatment of COVID-19.
- Molecular weight: 628.81
- Formula: C37H48N4O5
- CLOGP: 6.09
- LIPINSKI: 2
- HAC: 9
- HDO: 4
- TPSA: 120
- ALOGS: -5.51
- ROTB: 15
- Status: OFP
Legend: OFP - off patent OFM - off market ONP - on patent
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