DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
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Structure 🔎
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L1000
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DrugCentral 2023 🐕
2022 Update-Veterinary Drugs & Uses
Search
Structure 🔎
Similarity 🔎
Smart API
Redial
About
Download
L1000
FAQ
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All
FDA-approved
EMA-approved
PMDA-approved
Target Card Uniprot Example:
P23975
lonidamine 🐶
Veterinary Use |
Indications/Contra
| FAERs-F
| FAERs-M
| Orange Bk
| BioActivity |
Stem definition
Drug id
CAS RN
1598
50264-69-2
Description:
Molecule
Description
Molfile
Inchi
Smiles
Synonyms:
doridamina
lonidamine
diclondazolic acid
Molecular weight: 321.16
Formula: C15H10Cl2N2O2
CLOGP: 5.12
LIPINSKI: 1
HAC: 4
HDO: 1
TPSA: 55.12
ALOGS: -4.55
ROTB: 3
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
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Source
Code
Description
ATC
L01XX07
ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
ANTINEOPLASTIC AGENTS
OTHER ANTINEOPLASTIC AGENTS
Other antineoplastic agents
CHEBI has role
CHEBI:35610
antineoplastic agents
CHEBI has role
CHEBI:78366
hexokinase type IV glucokinase inhibitor
CHEBI has role
CHEBI:145047
antispermatogenic agents
CHEBI has role
CHEBI:176497
geroprotectors
MeSH PA
D000890
Anti-Infective Agents
MeSH PA
D000970
Antineoplastic Agents
MeSH PA
D000977
Antiparasitic Agents
MeSH PA
D000981
Antiprotozoal Agents
MeSH PA
D000988
Antispermatogenic Agents
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Drug Use
| Suggest Off label Use Form|
|View source of the data|
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Disease
Relation
SNOMED_ID
DOID
Malignant tumor of lung
indication
363358000
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🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
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Dissociation level
Dissociation constant
Type (acidic/basic)
pKa1
3.85
acidic
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Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
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Target
Class
Pharos
UniProt
Action
Type
Activity value
(-log[M])
Mechanism
action
Bioact source
MoA source
Mitochondrial pyruvate carrier 2
Transporter
O95563
MPC2_HUMAN
INHIBITOR
IC50
5.34
IUPHAR
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External reference:
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entries
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ID
Source
12601
IUPHAR_LIGAND_ID
39562
PUBCHEM_CID
4324
INN_ID
C0065175
UMLSCUI
C016371
MESH_SUPPLEMENTAL_RECORD_UI
CHEBI:50138
CHEBI
CHEMBL1257030
ChEMBL_ID
D07257
KEGG_DRUG
DB06266
DRUGBANK_ID
U78804BIDR
UNII
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Pharmaceutical products:
None
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Structure 🔎
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lonidamine