lonidamine Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
1598 50264-69-2

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • doridamina
  • lonidamine
  • diclondazolic acid
  • Molecular weight: 321.16
  • Formula: C15H10Cl2N2O2
  • CLOGP: 5.03
  • LIPINSKI: 1
  • HAC: 4
  • HDO: 1
  • TPSA: 55.12
  • ALOGS: -4.55
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
ATC L01XX07 ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
ANTINEOPLASTIC AGENTS
OTHER ANTINEOPLASTIC AGENTS
Other antineoplastic agents
MeSH PA D000890 Anti-Infective Agents
MeSH PA D000970 Antineoplastic Agents
MeSH PA D000977 Antiparasitic Agents
MeSH PA D000981 Antiprotozoal Agents
MeSH PA D000988 Antispermatogenic Agents
MeSH PA D003270 Contraceptive Agents
MeSH PA D003272 Contraceptive Agents, Male
MeSH PA D009676 Noxae
MeSH PA D011838 Radiation-Sensitizing Agents
MeSH PA D012102 Reproductive Control Agents
MeSH PA D014344 Trypanocidal Agents
CHEBI has role CHEBI:35610 cytostatic
CHEBI has role CHEBI:145047 antispermatogenic

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Malignant tumor of lung indication 363358000

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.85 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D07257 KEGG_DRUG
C0065175 UMLSCUI
CHEBI:50138 CHEBI
CHEMBL1257030 ChEMBL_ID
DB06266 DRUGBANK_ID
C016371 MESH_SUPPLEMENTAL_RECORD_UI
39562 PUBCHEM_CID
4324 INN_ID
U78804BIDR UNII

Pharmaceutical products:

None