leuprorelin ๐Ÿถ Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
pituitary hormone-release stimulating peptides 1559 53714-56-0

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • leuprorelin
  • leuprolide acetate
  • eligard
  • leupline
  • leuprolide
  • leuprorelin acetate
  • leuprorelin mesilate
A potent synthetic long-acting agonist of GONADOTROPIN-RELEASING HORMONE that regulates the synthesis and release of pituitary gonadotropins, LUTEINIZING HORMONE and FOLLICLE STIMULATING HORMONE.
  • Molecular weight: 1209.42
  • Formula: C59H84N16O12
  • CLOGP: -3.18
  • LIPINSKI: 3
  • HAC: 28
  • HDO: 16
  • TPSA: 429.04
  • ALOGS: -4.55
  • ROTB: 32

  • Status: OFP

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

DoseUnitRoute
60 mcg implant
1 mg P
0.13 mg P

ADMET properties:

Approvals:

FDA Adverse Event Reporting System (Female)

FDA Adverse Event Reporting System (Male)

FDA Adverse Event Reporting System (Geriatric)

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

Drug Use | Suggest Off label Use Form| |View source of the data|




๐Ÿถ Veterinary Drug Use

None

๐Ÿถ Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Orange Book patent data (new drug applications)

Orange Book exclusivity data (new drug applications)

Bioactivity Summary:

External reference:

Pharmaceutical products:

leuprorelin