Stem definition | Drug id | CAS RN |
---|---|---|
1552 | 75706-12-6 |
Dose | Unit | Route |
---|---|---|
20 | mg | O |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 2 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 0.02 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 1 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 1.23 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 80 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
Date | Agency | Company | Orphan |
---|---|---|---|
Sept. 10, 1998 | FDA | SANOFI AVENTIS US |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Rheumatoid arthritis | 8335.01 | 13.20 | 11680 | 381033 | 370924 | 55528430 |
Drug ineffective | 6788.83 | 13.20 | 17639 | 375074 | 901350 | 54998004 |
Drug intolerance | 4883.97 | 13.20 | 7491 | 385222 | 257327 | 55642027 |
Contraindicated product administered | 4035.00 | 13.20 | 5689 | 387024 | 180597 | 55718757 |
Joint swelling | 3633.66 | 13.20 | 6909 | 385804 | 282891 | 55616463 |
Treatment failure | 2911.75 | 13.20 | 4661 | 388052 | 165731 | 55733623 |
Synovitis | 2860.23 | 13.20 | 4488 | 388225 | 156817 | 55742537 |
Arthropathy | 2495.07 | 13.20 | 4767 | 387946 | 195508 | 55703846 |
Therapeutic product effect decreased | 2356.72 | 13.20 | 4230 | 388483 | 165222 | 55734132 |
Pemphigus | 2136.57 | 13.20 | 3886 | 388827 | 153326 | 55746028 |
Systemic lupus erythematosus | 1966.46 | 13.20 | 4058 | 388655 | 176020 | 55723334 |
Abdominal discomfort | 1912.22 | 13.20 | 5222 | 387491 | 272052 | 55627302 |
Swelling | 1833.84 | 13.20 | 4694 | 388019 | 235077 | 55664277 |
Hand deformity | 1752.85 | 13.20 | 3266 | 389447 | 131226 | 55768128 |
Glossodynia | 1743.65 | 13.20 | 3503 | 389210 | 148955 | 55750399 |
Alopecia | 1711.93 | 13.20 | 5205 | 387508 | 288253 | 55611101 |
Pain | 1468.53 | 13.20 | 8741 | 383972 | 654443 | 55244911 |
Death | 1449.38 | 13.20 | 308 | 392405 | 341118 | 55558236 |
Hepatic enzyme increased | 1284.43 | 13.20 | 3332 | 389381 | 168052 | 55731302 |
Arthralgia | 1244.65 | 13.20 | 6821 | 385892 | 494848 | 55404506 |
Anti-cyclic citrullinated peptide antibody positive | 1150.53 | 13.20 | 2286 | 390427 | 96314 | 55803040 |
Wound | 1077.08 | 13.20 | 2735 | 389978 | 136069 | 55763285 |
Hypersensitivity | 1014.88 | 13.20 | 4001 | 388712 | 252407 | 55646947 |
Rheumatoid factor positive | 1013.18 | 13.20 | 1767 | 390946 | 67293 | 55832061 |
Acute kidney injury | 997.03 | 13.20 | 229 | 392484 | 240534 | 55658820 |
Peripheral swelling | 984.57 | 13.20 | 3731 | 388982 | 230995 | 55668359 |
Therapeutic product effect incomplete | 965.61 | 13.20 | 2223 | 390490 | 103808 | 55795546 |
Hypotension | 965.01 | 13.20 | 276 | 392437 | 250232 | 55649122 |
Pericarditis | 937.77 | 13.20 | 2234 | 390479 | 106689 | 55792665 |
Musculoskeletal stiffness | 929.43 | 13.20 | 2791 | 389922 | 153216 | 55746138 |
Drug hypersensitivity | 889.03 | 13.20 | 4037 | 388676 | 271168 | 55628186 |
C-reactive protein abnormal | 888.09 | 13.20 | 1187 | 391526 | 35622 | 55863732 |
Rash | 852.27 | 13.20 | 6115 | 386598 | 486932 | 55412422 |
Toxicity to various agents | 847.27 | 13.20 | 257 | 392456 | 224307 | 55675047 |
Completed suicide | 841.73 | 13.20 | 19 | 392694 | 133814 | 55765540 |
Constipation | 832.07 | 13.20 | 194 | 392519 | 201749 | 55697605 |
Discomfort | 821.54 | 13.20 | 2512 | 390201 | 139249 | 55760105 |
Drug interaction | 743.93 | 13.20 | 267 | 392446 | 209488 | 55689866 |
Anaemia | 735.55 | 13.20 | 481 | 392232 | 267030 | 55632324 |
Folliculitis | 718.49 | 13.20 | 1338 | 391375 | 53641 | 55845713 |
Muscle injury | 711.65 | 13.20 | 1298 | 391415 | 51202 | 55848152 |
Infection | 709.70 | 13.20 | 3021 | 389692 | 197185 | 55702169 |
Gastrointestinal disorder | 686.57 | 13.20 | 2033 | 390680 | 110669 | 55788685 |
Lower respiratory tract infection | 657.20 | 13.20 | 2026 | 390687 | 112768 | 55786586 |
Irritable bowel syndrome | 654.77 | 13.20 | 1464 | 391249 | 66994 | 55832360 |
Impaired healing | 651.07 | 13.20 | 1690 | 391023 | 85151 | 55814203 |
Infusion related reaction | 644.38 | 13.20 | 3025 | 389688 | 205906 | 55693448 |
Product use issue | 629.10 | 13.20 | 2768 | 389945 | 183273 | 55716081 |
Loss of personal independence in daily activities | 627.00 | 13.20 | 1600 | 391113 | 79769 | 55819585 |
Febrile neutropenia | 620.70 | 13.20 | 27 | 392686 | 105518 | 55793836 |
Red blood cell sedimentation rate abnormal | 617.84 | 13.20 | 706 | 392007 | 17967 | 55881387 |
Psoriatic arthropathy | 605.60 | 13.20 | 1489 | 391224 | 72519 | 55826835 |
Helicobacter infection | 602.61 | 13.20 | 1477 | 391236 | 71791 | 55827563 |
Dehydration | 601.99 | 13.20 | 180 | 392533 | 158645 | 55740709 |
Duodenal ulcer perforation | 583.76 | 13.20 | 1398 | 391315 | 66944 | 55832410 |
Ill-defined disorder | 575.68 | 13.20 | 1393 | 391320 | 67150 | 55832204 |
Condition aggravated | 557.26 | 13.20 | 4213 | 388500 | 340685 | 55558669 |
Seizure | 542.03 | 13.20 | 107 | 392606 | 125012 | 55774342 |
Tremor | 532.08 | 13.20 | 100 | 392613 | 120989 | 55778365 |
Hyponatraemia | 527.63 | 13.20 | 51 | 392662 | 102088 | 55797266 |
Red blood cell sedimentation rate increased | 513.45 | 13.20 | 919 | 391794 | 35704 | 55863650 |
Sleep disorder due to general medical condition, insomnia type | 503.96 | 13.20 | 1004 | 391709 | 42334 | 55857020 |
Blister | 498.40 | 13.20 | 1782 | 390931 | 107105 | 55792249 |
Anxiety | 482.72 | 13.20 | 384 | 392329 | 192788 | 55706566 |
Product dose omission issue | 482.27 | 13.20 | 431 | 392282 | 204322 | 55695032 |
Maternal exposure during pregnancy | 482.26 | 13.20 | 2600 | 390113 | 186953 | 55712401 |
Somnolence | 476.35 | 13.20 | 274 | 392439 | 163139 | 55736215 |
Fall | 463.95 | 13.20 | 1140 | 391573 | 356370 | 55542984 |
Overdose | 463.67 | 13.20 | 88 | 392625 | 105742 | 55793612 |
Dizziness | 460.78 | 13.20 | 1235 | 391478 | 374905 | 55524449 |
C-reactive protein increased | 446.62 | 13.20 | 1385 | 391328 | 77299 | 55822055 |
Intentional overdose | 438.96 | 13.20 | 7 | 392706 | 68110 | 55831244 |
Cardiac arrest | 430.62 | 13.20 | 49 | 392664 | 86265 | 55813089 |
Urinary tract infection | 413.79 | 13.20 | 649 | 392064 | 239864 | 55659490 |
Bradycardia | 407.98 | 13.20 | 14 | 392699 | 67490 | 55831864 |
Disease progression | 407.95 | 13.20 | 114 | 392599 | 105059 | 55794295 |
Bone erosion | 401.73 | 13.20 | 509 | 392204 | 14465 | 55884889 |
Dyspnoea | 399.10 | 13.20 | 2463 | 390250 | 590114 | 55309240 |
Thrombocytopenia | 390.45 | 13.20 | 233 | 392480 | 135991 | 55763363 |
Rheumatoid nodule | 373.46 | 13.20 | 489 | 392224 | 14368 | 55884986 |
Knee arthroplasty | 372.04 | 13.20 | 900 | 391813 | 43359 | 55855995 |
Hypokalaemia | 363.23 | 13.20 | 104 | 392609 | 94333 | 55805021 |
Mobility decreased | 355.71 | 13.20 | 1501 | 391212 | 97490 | 55801864 |
Neutropenia | 354.57 | 13.20 | 348 | 392365 | 157819 | 55741535 |
Electrocardiogram QT prolonged | 342.10 | 13.20 | 8 | 392705 | 54580 | 55844774 |
Sepsis | 333.15 | 13.20 | 291 | 392422 | 139549 | 55759805 |
Tachycardia | 329.75 | 13.20 | 163 | 392550 | 105713 | 55793641 |
Oedema peripheral | 313.94 | 13.20 | 442 | 392271 | 170812 | 55728542 |
Abdominal pain | 313.31 | 13.20 | 854 | 391859 | 257951 | 55641403 |
Chest discomfort | 311.20 | 13.20 | 150 | 392563 | 98707 | 55800647 |
Suicide attempt | 309.14 | 13.20 | 25 | 392688 | 57811 | 55841543 |
Hip arthroplasty | 304.09 | 13.20 | 766 | 391947 | 37857 | 55861497 |
Stomatitis | 302.77 | 13.20 | 1651 | 391062 | 119159 | 55780195 |
Depressed level of consciousness | 302.73 | 13.20 | 24 | 392689 | 56409 | 55842945 |
Blood iron abnormal | 292.88 | 13.20 | 219 | 392494 | 3158 | 55896196 |
Vision blurred | 289.64 | 13.20 | 108 | 392605 | 82835 | 55816519 |
Atrial fibrillation | 289.20 | 13.20 | 203 | 392510 | 108694 | 55790660 |
Balance disorder | 285.64 | 13.20 | 89 | 392624 | 76431 | 55822923 |
Platelet count decreased | 284.25 | 13.20 | 197 | 392516 | 106186 | 55793168 |
Sinusitis | 281.18 | 13.20 | 2346 | 390367 | 195235 | 55704119 |
Plasma cell myeloma | 280.72 | 13.20 | 10 | 392703 | 46636 | 55852718 |
Hyperkalaemia | 277.48 | 13.20 | 20 | 392693 | 50845 | 55848509 |
Muscle spasms | 273.84 | 13.20 | 333 | 392380 | 137038 | 55762316 |
Cardio-respiratory arrest | 271.95 | 13.20 | 33 | 392680 | 55288 | 55844066 |
Chest pain | 271.87 | 13.20 | 573 | 392140 | 189224 | 55710130 |
Respiratory failure | 268.97 | 13.20 | 165 | 392548 | 94897 | 55804457 |
Pulmonary embolism | 267.34 | 13.20 | 213 | 392500 | 106911 | 55792443 |
Asthenia | 264.05 | 13.20 | 1363 | 391350 | 341610 | 55557744 |
Foot deformity | 255.63 | 13.20 | 534 | 392179 | 23291 | 55876063 |
Cerebrovascular accident | 254.55 | 13.20 | 192 | 392521 | 99078 | 55800276 |
Agitation | 248.80 | 13.20 | 45 | 392668 | 55991 | 55843363 |
Hypoglycaemia | 247.43 | 13.20 | 45 | 392668 | 55770 | 55843584 |
Cardiac failure congestive | 245.76 | 13.20 | 154 | 392559 | 87566 | 55811788 |
Haemoglobin decreased | 244.98 | 13.20 | 347 | 392366 | 133790 | 55765564 |
Epistaxis | 244.76 | 13.20 | 81 | 392632 | 66942 | 55832412 |
Osteoarthritis | 241.39 | 13.20 | 1155 | 391558 | 79141 | 55820213 |
Hallucination | 239.92 | 13.20 | 30 | 392683 | 49119 | 55850235 |
Neutrophil count decreased | 237.00 | 13.20 | 33 | 392680 | 49789 | 55849565 |
Gastrointestinal haemorrhage | 236.36 | 13.20 | 117 | 392596 | 75834 | 55823520 |
Rheumatic fever | 235.62 | 13.20 | 580 | 392133 | 28247 | 55871107 |
Inflammation | 235.45 | 13.20 | 1031 | 391682 | 68040 | 55831314 |
Osteoporosis | 232.94 | 13.20 | 846 | 391867 | 51206 | 55848148 |
Blood cholesterol increased | 231.36 | 13.20 | 1062 | 391651 | 71517 | 55827837 |
Asthma | 230.46 | 13.20 | 268 | 392445 | 112502 | 55786852 |
Tenosynovitis | 230.10 | 13.20 | 354 | 392359 | 12107 | 55887247 |
Cough | 229.42 | 13.20 | 983 | 391730 | 258978 | 55640376 |
Blood glucose increased | 229.02 | 13.20 | 119 | 392594 | 75032 | 55824322 |
Deformity | 228 | 13.20 | 318 | 392395 | 9937 | 55889417 |
Sedation | 227.04 | 13.20 | 3 | 392710 | 34851 | 55864503 |
Cognitive disorder | 225.76 | 13.20 | 36 | 392677 | 49097 | 55850257 |
Musculoskeletal disorder | 225.42 | 13.20 | 446 | 392267 | 18701 | 55880653 |
Swollen joint count increased | 225.24 | 13.20 | 512 | 392201 | 23672 | 55875682 |
Syncope | 224.51 | 13.20 | 254 | 392459 | 107945 | 55791409 |
Cardiac failure | 220.64 | 13.20 | 151 | 392562 | 81942 | 55817412 |
Hypoxia | 219.29 | 13.20 | 53 | 392660 | 53844 | 55845510 |
Wrong technique in product usage process | 218.27 | 13.20 | 67 | 392646 | 58101 | 55841253 |
Metabolic acidosis | 217.55 | 13.20 | 17 | 392696 | 40437 | 55858917 |
Drug tolerance decreased | 213.38 | 13.20 | 356 | 392357 | 13055 | 55886299 |
Renal failure | 212.74 | 13.20 | 275 | 392438 | 110225 | 55789129 |
COVID-19 | 211.32 | 13.20 | 131 | 392582 | 74927 | 55824427 |
Myalgia | 207.67 | 13.20 | 377 | 392336 | 131648 | 55767706 |
Disability | 207.19 | 13.20 | 385 | 392328 | 15395 | 55883959 |
Pancytopenia | 207.14 | 13.20 | 188 | 392525 | 88527 | 55810827 |
Arthritis | 206.27 | 13.20 | 1297 | 391416 | 98555 | 55800799 |
Lactic acidosis | 201.45 | 13.20 | 11 | 392702 | 35335 | 55864019 |
Unresponsive to stimuli | 201.33 | 13.20 | 4 | 392709 | 31721 | 55867633 |
Vomiting | 199.82 | 13.20 | 2370 | 390343 | 495858 | 55403496 |
Hyperhidrosis | 199.45 | 13.20 | 217 | 392496 | 93871 | 55805483 |
Flushing | 199.22 | 13.20 | 121 | 392592 | 69979 | 55829375 |
Granuloma skin | 197.60 | 13.20 | 245 | 392468 | 6806 | 55892548 |
Joint range of motion decreased | 196.44 | 13.20 | 500 | 392213 | 24865 | 55874489 |
Dysphagia | 195.72 | 13.20 | 170 | 392543 | 81777 | 55817577 |
Chills | 194.79 | 13.20 | 258 | 392455 | 102346 | 55797008 |
Coma | 193.14 | 13.20 | 87 | 392626 | 59568 | 55839786 |
Blood parathyroid hormone decreased | 191.40 | 13.20 | 263 | 392450 | 8101 | 55891253 |
Decreased appetite | 190.91 | 13.20 | 833 | 391880 | 218398 | 55680956 |
Panniculitis | 190.79 | 13.20 | 286 | 392427 | 9556 | 55889798 |
Mental status changes | 190.27 | 13.20 | 20 | 392693 | 37481 | 55861873 |
Pulmonary oedema | 189.94 | 13.20 | 60 | 392653 | 51083 | 55848271 |
Bone pain | 189.75 | 13.20 | 57 | 392656 | 50128 | 55849226 |
Nausea | 189.62 | 13.20 | 3982 | 388731 | 760196 | 55139158 |
Gastrooesophageal reflux disease | 189.00 | 13.20 | 181 | 392532 | 83076 | 55816278 |
White blood cell count decreased | 188.28 | 13.20 | 371 | 392342 | 125619 | 55773735 |
Pneumonia aspiration | 188.16 | 13.20 | 9 | 392704 | 32402 | 55866952 |
Lethargy | 188.12 | 13.20 | 62 | 392651 | 51379 | 55847975 |
Depression | 187.98 | 13.20 | 636 | 392077 | 179481 | 55719873 |
International normalised ratio increased | 187.84 | 13.20 | 39 | 392674 | 44002 | 55855352 |
Pleural effusion | 185.82 | 13.20 | 193 | 392520 | 85287 | 55814067 |
Pulmonary fibrosis | 183.95 | 13.20 | 540 | 392173 | 29218 | 55870136 |
Joint stiffness | 181.27 | 13.20 | 602 | 392111 | 34823 | 55864531 |
Hyperglycaemia | 180.57 | 13.20 | 26 | 392687 | 38255 | 55861099 |
Respiratory arrest | 176.20 | 13.20 | 9 | 392704 | 30616 | 55868738 |
Feeling abnormal | 176.00 | 13.20 | 422 | 392291 | 133180 | 55766174 |
Deafness transitory | 175.28 | 13.20 | 129 | 392584 | 1813 | 55897541 |
Blood pressure decreased | 173.36 | 13.20 | 98 | 392615 | 58952 | 55840402 |
Deep vein thrombosis | 172.80 | 13.20 | 169 | 392544 | 76808 | 55822546 |
Therapeutic response decreased | 172.59 | 13.20 | 778 | 391935 | 51980 | 55847374 |
Finger deformity | 170.78 | 13.20 | 220 | 392493 | 6357 | 55892997 |
Neuropathy peripheral | 169.79 | 13.20 | 285 | 392428 | 102608 | 55796746 |
Fibromyalgia | 169.53 | 13.20 | 844 | 391869 | 58759 | 55840595 |
Rhabdomyolysis | 167.34 | 13.20 | 39 | 392674 | 40619 | 55858735 |
Encephalopathy | 164.30 | 13.20 | 25 | 392688 | 35300 | 55864054 |
Grip strength decreased | 163.58 | 13.20 | 355 | 392358 | 15901 | 55883453 |
Orthostatic hypotension | 160.25 | 13.20 | 21 | 392692 | 33178 | 55866176 |
Intentional self-injury | 159.20 | 13.20 | 3 | 392710 | 24989 | 55874365 |
Adverse drug reaction | 158.27 | 13.20 | 883 | 391830 | 64249 | 55835105 |
Diarrhoea | 157.86 | 13.20 | 3328 | 389385 | 635179 | 55264175 |
Fluid retention | 156.96 | 13.20 | 91 | 392622 | 53987 | 55845367 |
Disturbance in attention | 156.07 | 13.20 | 21 | 392692 | 32519 | 55866835 |
Adverse event | 154.57 | 13.20 | 780 | 391933 | 54596 | 55844758 |
Product quality issue | 153.37 | 13.20 | 20 | 392693 | 31716 | 55867638 |
Nasopharyngitis | 152.68 | 13.20 | 2275 | 390438 | 218684 | 55680670 |
Pneumonia | 152.64 | 13.20 | 1964 | 390749 | 405134 | 55494220 |
Liver function test increased | 151.05 | 13.20 | 486 | 392227 | 27647 | 55871707 |
Drug withdrawal syndrome | 150.68 | 13.20 | 7 | 392706 | 25850 | 55873504 |
Dysarthria | 149.38 | 13.20 | 45 | 392668 | 39505 | 55859849 |
Restlessness | 149.28 | 13.20 | 9 | 392704 | 26577 | 55872777 |
Ascites | 148.71 | 13.20 | 39 | 392674 | 37505 | 55861849 |
Disorientation | 145.08 | 13.20 | 38 | 392675 | 36575 | 55862779 |
Urinary retention | 142.36 | 13.20 | 15 | 392698 | 28059 | 55871295 |
Premature delivery | 141.04 | 13.20 | 13 | 392700 | 27047 | 55872307 |
Hospitalisation | 140.90 | 13.20 | 190 | 392523 | 74810 | 55824544 |
Thrombosis | 139.82 | 13.20 | 125 | 392588 | 59302 | 55840052 |
Hypervolaemia | 139.82 | 13.20 | 12 | 392701 | 26446 | 55872908 |
Skin ulcer | 138.99 | 13.20 | 586 | 392127 | 38022 | 55861332 |
Limb deformity | 136.89 | 13.20 | 152 | 392561 | 3743 | 55895611 |
Oxygen saturation decreased | 136.07 | 13.20 | 213 | 392500 | 78854 | 55820500 |
Intentional product misuse | 135.38 | 13.20 | 97 | 392616 | 51407 | 55847947 |
Chronic kidney disease | 135.09 | 13.20 | 62 | 392651 | 41994 | 55857360 |
Rectal haemorrhage | 134.97 | 13.20 | 60 | 392653 | 41407 | 55857947 |
Full blood count decreased | 133.89 | 13.20 | 7 | 392706 | 23342 | 55876012 |
Paraesthesia | 132.63 | 13.20 | 466 | 392247 | 130048 | 55769306 |
Chronic obstructive pulmonary disease | 132.43 | 13.20 | 123 | 392590 | 57292 | 55842062 |
Pyrexia | 132.04 | 13.20 | 2091 | 390622 | 416682 | 55482672 |
Injection site pain | 131.58 | 13.20 | 400 | 392313 | 116718 | 55782636 |
Respiratory distress | 131.07 | 13.20 | 30 | 392683 | 31637 | 55867717 |
Rheumatoid lung | 130.61 | 13.20 | 134 | 392579 | 3006 | 55896348 |
Blood potassium decreased | 130.60 | 13.20 | 53 | 392660 | 38619 | 55860735 |
Haemorrhage | 129.86 | 13.20 | 121 | 392592 | 56276 | 55843078 |
Cerebral haemorrhage | 129.09 | 13.20 | 22 | 392691 | 28584 | 55870770 |
Pulmonary toxicity | 129.09 | 13.20 | 212 | 392501 | 7671 | 55891683 |
Skin necrosis | 129.04 | 13.20 | 274 | 392439 | 12087 | 55887267 |
Multiple organ dysfunction syndrome | 129.02 | 13.20 | 107 | 392606 | 52663 | 55846691 |
Dry skin | 128.78 | 13.20 | 85 | 392628 | 47024 | 55852330 |
Altered state of consciousness | 128.64 | 13.20 | 8 | 392705 | 23013 | 55876341 |
Hypomagnesaemia | 127.79 | 13.20 | 13 | 392700 | 25002 | 55874352 |
Dysgeusia | 127.31 | 13.20 | 63 | 392650 | 40852 | 55858502 |
Suicidal ideation | 125.90 | 13.20 | 130 | 392583 | 57612 | 55841742 |
Dyskinesia | 125.74 | 13.20 | 25 | 392688 | 29083 | 55870271 |
Melaena | 124.96 | 13.20 | 23 | 392690 | 28267 | 55871087 |
Generalised tonic-clonic seizure | 124.84 | 13.20 | 21 | 392692 | 27545 | 55871809 |
Erythema | 124.69 | 13.20 | 611 | 392102 | 155328 | 55744026 |
Urinary incontinence | 124.52 | 13.20 | 27 | 392686 | 29558 | 55869796 |
Fatigue | 124.10 | 13.20 | 6701 | 386012 | 781851 | 55117503 |
Musculoskeletal deformity | 121.40 | 13.20 | 94 | 392619 | 1432 | 55897922 |
Palpitations | 121.06 | 13.20 | 328 | 392385 | 99344 | 55800010 |
Lymphocyte count decreased | 120.68 | 13.20 | 24 | 392689 | 27915 | 55871439 |
Haematoma | 118.11 | 13.20 | 38 | 392675 | 31981 | 55867373 |
Aphasia | 117.82 | 13.20 | 33 | 392680 | 30382 | 55868972 |
Cardiac disorder | 117.27 | 13.20 | 89 | 392624 | 45798 | 55853556 |
Blood calcium decreased | 117.24 | 13.20 | 14 | 392699 | 23755 | 55875599 |
Incorrect dose administered | 117.19 | 13.20 | 116 | 392597 | 52431 | 55846923 |
Heart rate increased | 116.94 | 13.20 | 254 | 392459 | 83019 | 55816335 |
Abnormal behaviour | 116.49 | 13.20 | 6 | 392707 | 20266 | 55879088 |
Dyspnoea exertional | 114.91 | 13.20 | 127 | 392586 | 54562 | 55844792 |
Presyncope | 114.73 | 13.20 | 20 | 392693 | 25562 | 55873792 |
Type 2 diabetes mellitus | 114.28 | 13.20 | 636 | 392077 | 46226 | 55853128 |
Metastases to liver | 113.50 | 13.20 | 10 | 392703 | 21576 | 55877778 |
Blood creatinine increased | 113.10 | 13.20 | 244 | 392469 | 79947 | 55819407 |
Adverse reaction | 112.66 | 13.20 | 221 | 392492 | 9206 | 55890148 |
Muscle spasticity | 111.89 | 13.20 | 350 | 392363 | 19610 | 55879744 |
Depressed mood | 111.61 | 13.20 | 57 | 392656 | 36302 | 55863052 |
Impaired work ability | 110.50 | 13.20 | 285 | 392428 | 14287 | 55885067 |
Epilepsy | 110.40 | 13.20 | 21 | 392692 | 25210 | 55874144 |
Liver injury | 109.51 | 13.20 | 579 | 392134 | 41269 | 55858085 |
Pulmonary hypertension | 109.36 | 13.20 | 57 | 392656 | 35887 | 55863467 |
Aggression | 108.45 | 13.20 | 13 | 392700 | 21993 | 55877361 |
Foetal exposure during pregnancy | 108.42 | 13.20 | 50 | 392663 | 33773 | 55865581 |
Drug level increased | 107.90 | 13.20 | 10 | 392703 | 20715 | 55878639 |
Ear pain | 107.43 | 13.20 | 464 | 392249 | 30426 | 55868928 |
Inappropriate schedule of product administration | 106.15 | 13.20 | 268 | 392445 | 83119 | 55816235 |
Dysuria | 105.59 | 13.20 | 41 | 392672 | 30688 | 55868666 |
Haematochezia | 105.21 | 13.20 | 90 | 392623 | 43628 | 55855726 |
Irritability | 104.15 | 13.20 | 38 | 392675 | 29550 | 55869804 |
Nodule | 103.92 | 13.20 | 326 | 392387 | 18293 | 55881061 |
Flatulence | 103.85 | 13.20 | 44 | 392669 | 31244 | 55868110 |
Drug reaction with eosinophilia and systemic symptoms | 103.20 | 13.20 | 41 | 392672 | 30263 | 55869091 |
Night sweats | 102.95 | 13.20 | 563 | 392150 | 40650 | 55858704 |
Device dislocation | 102.87 | 13.20 | 17 | 392696 | 22589 | 55876765 |
Psychotic disorder | 102.25 | 13.20 | 20 | 392693 | 23538 | 55875816 |
Colitis | 101.94 | 13.20 | 85 | 392628 | 41726 | 55857628 |
Right ventricular failure | 100.36 | 13.20 | 3 | 392710 | 16376 | 55882978 |
Memory impairment | 99.82 | 13.20 | 292 | 392421 | 86265 | 55813089 |
Ejection fraction decreased | 99.58 | 13.20 | 11 | 392702 | 19830 | 55879524 |
Sleep disorder | 99.56 | 13.20 | 810 | 391903 | 66853 | 55832501 |
Oropharyngeal pain | 98.57 | 13.20 | 280 | 392433 | 83508 | 55815846 |
Full blood count abnormal | 98.33 | 13.20 | 31 | 392682 | 26431 | 55872923 |
Foot operation | 97.88 | 13.20 | 165 | 392548 | 6102 | 55893252 |
Vertigo | 97.76 | 13.20 | 143 | 392570 | 54429 | 55844925 |
Shoulder arthroplasty | 97.66 | 13.20 | 125 | 392588 | 3588 | 55895766 |
Metastases to bone | 97.45 | 13.20 | 11 | 392702 | 19497 | 55879857 |
Gastrointestinal pain | 96.81 | 13.20 | 199 | 392514 | 8578 | 55890776 |
Pulmonary arterial hypertension | 96.79 | 13.20 | 32 | 392681 | 26471 | 55872883 |
Intentional product use issue | 96.64 | 13.20 | 1093 | 391620 | 98640 | 55800714 |
Body temperature increased | 96.01 | 13.20 | 483 | 392230 | 33759 | 55865595 |
Sleep apnoea syndrome | 96.00 | 13.20 | 31 | 392682 | 26030 | 55873324 |
Withdrawal syndrome | 95.87 | 13.20 | 9 | 392704 | 18453 | 55880901 |
Vaginal haemorrhage | 95.53 | 13.20 | 30 | 392683 | 25643 | 55873711 |
Abdominal distension | 95.35 | 13.20 | 254 | 392459 | 77372 | 55821982 |
Septic shock | 95.34 | 13.20 | 174 | 392539 | 60661 | 55838693 |
Joint destruction | 95.29 | 13.20 | 145 | 392568 | 4910 | 55894444 |
Oral mucosal exfoliation | 95.19 | 13.20 | 83 | 392630 | 1506 | 55897848 |
Hallucination, visual | 94.88 | 13.20 | 7 | 392706 | 17461 | 55881893 |
Sciatica | 94.56 | 13.20 | 396 | 392317 | 25614 | 55873740 |
Acute respiratory failure | 94.52 | 13.20 | 49 | 392664 | 30945 | 55868409 |
Pancreatitis acute | 92.35 | 13.20 | 30 | 392683 | 25094 | 55874260 |
Neutropenic sepsis | 92.26 | 13.20 | 3 | 392710 | 15182 | 55884172 |
Accidental overdose | 91.75 | 13.20 | 16 | 392697 | 20445 | 55878909 |
Circulatory collapse | 91.70 | 13.20 | 17 | 392696 | 20786 | 55878568 |
Blood creatine phosphokinase increased | 91.67 | 13.20 | 40 | 392673 | 27912 | 55871442 |
Mucosal inflammation | 91.50 | 13.20 | 98 | 392615 | 42712 | 55856642 |
Arrhythmia | 90.99 | 13.20 | 67 | 392646 | 35016 | 55864338 |
Blood urea increased | 90.35 | 13.20 | 29 | 392684 | 24444 | 55874910 |
Hypocalcaemia | 89.91 | 13.20 | 44 | 392669 | 28716 | 55870638 |
Neurotoxicity | 89.74 | 13.20 | 5 | 392708 | 15790 | 55883564 |
Hemiparesis | 89.66 | 13.20 | 20 | 392693 | 21470 | 55877884 |
Abdominal pain lower | 89.54 | 13.20 | 25 | 392688 | 23067 | 55876287 |
Enthesopathy | 89.15 | 13.20 | 183 | 392530 | 7880 | 55891474 |
Bone marrow failure | 88.85 | 13.20 | 43 | 392670 | 28243 | 55871111 |
Transient ischaemic attack | 88.55 | 13.20 | 63 | 392650 | 33514 | 55865840 |
Ventricular tachycardia | 88.40 | 13.20 | 8 | 392705 | 16893 | 55882461 |
Clostridium difficile colitis | 87.74 | 13.20 | 13 | 392700 | 18725 | 55880629 |
Sinus tachycardia | 87.59 | 13.20 | 24 | 392689 | 22420 | 55876934 |
Red blood cell sedimentation rate | 87.54 | 13.20 | 128 | 392585 | 4180 | 55895174 |
Dementia | 87.43 | 13.20 | 9 | 392704 | 17149 | 55882205 |
Retinal toxicity | 87.24 | 13.20 | 70 | 392643 | 1126 | 55898228 |
Tuberculin test positive | 86.97 | 13.20 | 112 | 392601 | 3235 | 55896119 |
Myocardial infarction | 86.23 | 13.20 | 344 | 392369 | 92526 | 55806828 |
Physical disability | 86 | 13.20 | 94 | 392619 | 2273 | 55897081 |
Pericardial effusion | 85.83 | 13.20 | 41 | 392672 | 27134 | 55872220 |
Panic attack | 85.36 | 13.20 | 19 | 392694 | 20428 | 55878926 |
X-ray abnormal | 85.36 | 13.20 | 127 | 392586 | 4214 | 55895140 |
Weight decreased | 84.31 | 13.20 | 1177 | 391536 | 239537 | 55659817 |
Product administration error | 84.31 | 13.20 | 21 | 392692 | 20908 | 55878446 |
Joint effusion | 84.21 | 13.20 | 262 | 392451 | 14636 | 55884718 |
Acute myocardial infarction | 84.21 | 13.20 | 54 | 392659 | 30339 | 55869015 |
Joint laxity | 83.69 | 13.20 | 94 | 392619 | 2345 | 55897009 |
Therapy interrupted | 83.51 | 13.20 | 37 | 392676 | 25588 | 55873766 |
Therapy cessation | 83.29 | 13.20 | 43 | 392670 | 27221 | 55872133 |
Rash erythematous | 83.19 | 13.20 | 82 | 392631 | 37139 | 55862215 |
Hepatotoxicity | 82.86 | 13.20 | 433 | 392280 | 30720 | 55868634 |
Inappropriate antidiuretic hormone secretion | 82.58 | 13.20 | 3 | 392710 | 13753 | 55885601 |
Abortion spontaneous | 82.00 | 13.20 | 111 | 392602 | 43642 | 55855712 |
Upper gastrointestinal haemorrhage | 81.80 | 13.20 | 11 | 392702 | 17043 | 55882311 |
Toxic epidermal necrolysis | 81.58 | 13.20 | 26 | 392687 | 22016 | 55877338 |
Blood sodium decreased | 81.51 | 13.20 | 27 | 392686 | 22307 | 55877047 |
Face oedema | 81.50 | 13.20 | 15 | 392698 | 18437 | 55880917 |
Acute myeloid leukaemia | 81.28 | 13.20 | 11 | 392702 | 16961 | 55882393 |
Pollakiuria | 81.18 | 13.20 | 37 | 392676 | 25165 | 55874189 |
Burning sensation | 81.12 | 13.20 | 134 | 392579 | 48562 | 55850792 |
Haemoptysis | 80.98 | 13.20 | 42 | 392671 | 26518 | 55872836 |
Angioedema | 80.94 | 13.20 | 102 | 392611 | 41351 | 55858003 |
Musculoskeletal pain | 80.71 | 13.20 | 894 | 391819 | 80258 | 55819096 |
Rheumatoid factor negative | 80.70 | 13.20 | 51 | 392662 | 549 | 55898805 |
Drug eruption | 80.58 | 13.20 | 375 | 392338 | 25388 | 55873966 |
Arthrodesis | 80.17 | 13.20 | 96 | 392617 | 2570 | 55896784 |
Renal impairment | 80.09 | 13.20 | 291 | 392422 | 80422 | 55818932 |
Myoclonus | 80.05 | 13.20 | 7 | 392706 | 15196 | 55884158 |
Eye pain | 79.88 | 13.20 | 59 | 392654 | 30788 | 55868566 |
Diabetic ketoacidosis | 79.87 | 13.20 | 17 | 392696 | 18854 | 55880500 |
Accidental exposure to product | 79.68 | 13.20 | 36 | 392677 | 24611 | 55874743 |
Status epilepticus | 79.64 | 13.20 | 7 | 392706 | 15134 | 55884220 |
Emotional distress | 79.60 | 13.20 | 55 | 392658 | 29708 | 55869646 |
Product prescribing error | 79.56 | 13.20 | 31 | 392682 | 23155 | 55876199 |
Cerebral infarction | 79.04 | 13.20 | 29 | 392684 | 22476 | 55876878 |
Haematuria | 78.89 | 13.20 | 45 | 392668 | 26942 | 55872412 |
Product use in unapproved indication | 78.59 | 13.20 | 617 | 392096 | 140205 | 55759149 |
Hepatic function abnormal | 78.55 | 13.20 | 75 | 392638 | 34483 | 55864871 |
Spinal column injury | 78.52 | 13.20 | 81 | 392632 | 1829 | 55897525 |
Cholestasis | 78.50 | 13.20 | 45 | 392668 | 26868 | 55872486 |
Skin exfoliation | 78.28 | 13.20 | 85 | 392628 | 36815 | 55862539 |
Cholelithiasis | 78.21 | 13.20 | 96 | 392617 | 39368 | 55859986 |
Sinus bradycardia | 78.13 | 13.20 | 4 | 392709 | 13582 | 55885772 |
Drug ineffective for unapproved indication | 77.79 | 13.20 | 41 | 392672 | 25652 | 55873702 |
Multiple sclerosis | 77.57 | 13.20 | 49 | 392664 | 27753 | 55871601 |
Blood bilirubin increased | 77.44 | 13.20 | 71 | 392642 | 33283 | 55866071 |
Head injury | 75.89 | 13.20 | 40 | 392673 | 25026 | 55874328 |
Electrolyte imbalance | 74.79 | 13.20 | 17 | 392696 | 18016 | 55881338 |
Ulcer | 74.58 | 13.20 | 333 | 392380 | 22152 | 55877202 |
Tinnitus | 74.57 | 13.20 | 60 | 392653 | 29982 | 55869372 |
Cellulitis | 74.51 | 13.20 | 270 | 392443 | 74679 | 55824675 |
Device issue | 74.46 | 13.20 | 27 | 392686 | 21079 | 55878275 |
Ankylosing spondylitis | 74.04 | 13.20 | 193 | 392520 | 9737 | 55889617 |
Pain in jaw | 73.59 | 13.20 | 103 | 392610 | 39933 | 55859421 |
Product substitution issue | 73.51 | 13.20 | 8 | 392705 | 14591 | 55884763 |
Leukocytosis | 73.46 | 13.20 | 37 | 392676 | 23754 | 55875600 |
Agranulocytosis | 73.40 | 13.20 | 33 | 392680 | 22626 | 55876728 |
Blood pressure increased | 73.37 | 13.20 | 653 | 392060 | 144523 | 55754831 |
Creatinine renal clearance decreased | 73.25 | 13.20 | 8 | 392705 | 14551 | 55884803 |
Surgical failure | 73.14 | 13.20 | 57 | 392656 | 877 | 55898477 |
Loss of consciousness | 72.33 | 13.20 | 456 | 392257 | 108893 | 55790461 |
Muscle twitching | 72.18 | 13.20 | 13 | 392700 | 16229 | 55883125 |
Disseminated intravascular coagulation | 71.94 | 13.20 | 18 | 392695 | 17867 | 55881487 |
Swelling face | 71.51 | 13.20 | 180 | 392533 | 55889 | 55843465 |
Respiratory disorder | 70.62 | 13.20 | 442 | 392271 | 33515 | 55865839 |
Intestinal obstruction | 70.51 | 13.20 | 55 | 392658 | 27916 | 55871438 |
Pruritus allergic | 70.38 | 13.20 | 64 | 392649 | 1230 | 55898124 |
Speech disorder | 70.38 | 13.20 | 95 | 392618 | 37398 | 55861956 |
Poisoning | 69.98 | 13.20 | 5 | 392708 | 12808 | 55886546 |
Joint injury | 69.91 | 13.20 | 359 | 392354 | 25295 | 55874059 |
Lip swelling | 69.66 | 13.20 | 49 | 392664 | 26223 | 55873131 |
Small intestinal obstruction | 69.51 | 13.20 | 16 | 392697 | 16809 | 55882545 |
Lacrimation increased | 69.06 | 13.20 | 21 | 392692 | 18327 | 55881027 |
Coordination abnormal | 68.72 | 13.20 | 5 | 392708 | 12616 | 55886738 |
Mental disorder | 68.09 | 13.20 | 40 | 392673 | 23564 | 55875790 |
Muscular weakness | 67.84 | 13.20 | 438 | 392275 | 104014 | 55795340 |
Renal disorder | 67.58 | 13.20 | 64 | 392649 | 29541 | 55869813 |
Seronegative arthritis | 67.12 | 13.20 | 89 | 392624 | 2647 | 55896707 |
Pallor | 66.77 | 13.20 | 43 | 392670 | 24106 | 55875248 |
Transfusion | 66.59 | 13.20 | 8 | 392705 | 13512 | 55885842 |
Stevens-Johnson syndrome | 65.95 | 13.20 | 38 | 392675 | 22625 | 55876729 |
Loose body in joint | 65.76 | 13.20 | 61 | 392652 | 1204 | 55898150 |
Infusion site pain | 65.71 | 13.20 | 9 | 392704 | 13753 | 55885601 |
Bone swelling | 65.47 | 13.20 | 66 | 392647 | 1449 | 55897905 |
Breast cancer metastatic | 65.34 | 13.20 | 14 | 392699 | 15455 | 55883899 |
Dysphonia | 64.81 | 13.20 | 121 | 392592 | 41826 | 55857528 |
Red cell distribution width decreased | 64.68 | 13.20 | 68 | 392645 | 1571 | 55897783 |
Dystonia | 64.64 | 13.20 | 6 | 392707 | 12415 | 55886939 |
Mania | 64.37 | 13.20 | 4 | 392709 | 11516 | 55887838 |
Bacteraemia | 64.30 | 13.20 | 15 | 392698 | 15616 | 55883738 |
Haemorrhage intracranial | 64.19 | 13.20 | 7 | 392706 | 12748 | 55886606 |
Diplopia | 63.92 | 13.20 | 31 | 392682 | 20338 | 55879016 |
Dislocation of vertebra | 63.56 | 13.20 | 126 | 392587 | 5289 | 55894065 |
Feeling hot | 62.42 | 13.20 | 123 | 392590 | 41664 | 55857690 |
Vascular access complication | 62.39 | 13.20 | 68 | 392645 | 1639 | 55897715 |
Hypothermia | 62.36 | 13.20 | 7 | 392706 | 12463 | 55886891 |
Paranoia | 62.31 | 13.20 | 3 | 392710 | 10741 | 55888613 |
Incontinence | 62.25 | 13.20 | 3 | 392710 | 10732 | 55888622 |
Labelled drug-drug interaction medication error | 61.92 | 13.20 | 5 | 392708 | 11581 | 55887773 |
Skin discolouration | 61.55 | 13.20 | 90 | 392623 | 34266 | 55865088 |
Pancreatitis | 61.23 | 13.20 | 140 | 392573 | 44940 | 55854414 |
Hot flush | 61.15 | 13.20 | 148 | 392565 | 46578 | 55852776 |
Premature labour | 61.15 | 13.20 | 6 | 392707 | 11876 | 55887478 |
Eosinophilia | 60.84 | 13.20 | 32 | 392681 | 20045 | 55879309 |
Complication associated with device | 60.68 | 13.20 | 16 | 392697 | 15334 | 55884020 |
Anuria | 60.36 | 13.20 | 6 | 392707 | 11754 | 55887600 |
Metastases to central nervous system | 60.22 | 13.20 | 7 | 392706 | 12129 | 55887225 |
Basal cell carcinoma | 59.96 | 13.20 | 340 | 392373 | 24881 | 55874473 |
Visual acuity reduced | 59.96 | 13.20 | 35 | 392678 | 20691 | 55878663 |
Tuberculosis | 59.62 | 13.20 | 191 | 392522 | 10838 | 55888516 |
Subdural haematoma | 59.56 | 13.20 | 11 | 392702 | 13488 | 55885866 |
Caesarean section | 59.52 | 13.20 | 19 | 392694 | 16072 | 55883282 |
Incorrect product administration duration | 59.51 | 13.20 | 3 | 392710 | 10323 | 55889031 |
Mitral valve incompetence | 59.49 | 13.20 | 26 | 392687 | 18127 | 55881227 |
Cardiogenic shock | 59.11 | 13.20 | 20 | 392693 | 16305 | 55883049 |
Viral infection | 58.90 | 13.20 | 82 | 392631 | 31864 | 55867490 |
Ischaemic stroke | 58.65 | 13.20 | 22 | 392691 | 16820 | 55882534 |
Malnutrition | 58.51 | 13.20 | 13 | 392700 | 13995 | 55885359 |
Blood glucose decreased | 58.46 | 13.20 | 30 | 392683 | 19057 | 55880297 |
Diabetes mellitus inadequate control | 58.34 | 13.20 | 13 | 392700 | 13967 | 55885387 |
Fear | 58.06 | 13.20 | 16 | 392697 | 14892 | 55884462 |
Obstructive airways disorder | 57.84 | 13.20 | 24 | 392689 | 17258 | 55882096 |
Metastases to lung | 57.55 | 13.20 | 7 | 392706 | 11711 | 55887643 |
Tachypnoea | 57.46 | 13.20 | 18 | 392695 | 15412 | 55883942 |
Respiratory depression | 57.37 | 13.20 | 9 | 392704 | 12426 | 55886928 |
Paraesthesia oral | 57.23 | 13.20 | 15 | 392698 | 14434 | 55884920 |
Nervousness | 57.06 | 13.20 | 71 | 392642 | 28944 | 55870410 |
Haematemesis | 56.94 | 13.20 | 70 | 392643 | 28688 | 55870666 |
Peritonitis | 56.70 | 13.20 | 21 | 392692 | 16181 | 55883173 |
Device difficult to use | 56.53 | 13.20 | 5 | 392708 | 10756 | 55888598 |
Therapeutic response unexpected | 56.51 | 13.20 | 24 | 392689 | 17020 | 55882334 |
Systemic lupus erythematosus rash | 56.48 | 13.20 | 69 | 392644 | 1887 | 55897467 |
Mean platelet volume decreased | 56.35 | 13.20 | 73 | 392640 | 2121 | 55897233 |
Left ventricular dysfunction | 56.25 | 13.20 | 6 | 392707 | 11117 | 55888237 |
Delirium | 56.17 | 13.20 | 134 | 392579 | 42383 | 55856971 |
Brain oedema | 56.07 | 13.20 | 12 | 392701 | 13259 | 55886095 |
Mydriasis | 55.91 | 13.20 | 6 | 392707 | 11065 | 55888289 |
Hepatic failure | 55.90 | 13.20 | 92 | 392621 | 33394 | 55865960 |
Cholecystitis chronic | 55.65 | 13.20 | 3 | 392710 | 9745 | 55889609 |
Exostosis | 55.48 | 13.20 | 229 | 392484 | 14714 | 55884640 |
International normalised ratio fluctuation | 55.37 | 13.20 | 76 | 392637 | 2338 | 55897016 |
Joint dislocation | 54.89 | 13.20 | 237 | 392476 | 15536 | 55883818 |
Ankle arthroplasty | 54.83 | 13.20 | 59 | 392654 | 1401 | 55897953 |
Extrapyramidal disorder | 54.67 | 13.20 | 10 | 392703 | 12346 | 55887008 |
Cyanosis | 54.48 | 13.20 | 21 | 392692 | 15789 | 55883565 |
Emotional disorder | 54.29 | 13.20 | 10 | 392703 | 12285 | 55887069 |
Breast cancer stage III | 54.21 | 13.20 | 140 | 392573 | 7023 | 55892331 |
Wrist deformity | 54.05 | 13.20 | 66 | 392647 | 1804 | 55897550 |
Ileus | 53.88 | 13.20 | 15 | 392698 | 13867 | 55885487 |
Blood magnesium decreased | 53.87 | 13.20 | 9 | 392704 | 11865 | 55887489 |
Gastritis | 53.70 | 13.20 | 100 | 392613 | 34602 | 55864752 |
Muscle rigidity | 53.34 | 13.20 | 6 | 392707 | 10665 | 55888689 |
Ataxia | 53.28 | 13.20 | 17 | 392696 | 14386 | 55884968 |
Macular degeneration | 53.20 | 13.20 | 33 | 392680 | 18875 | 55880479 |
Adjustment disorder with depressed mood | 53.13 | 13.20 | 113 | 392600 | 4990 | 55894364 |
Malaise | 53.05 | 13.20 | 2064 | 390649 | 365796 | 55533558 |
Clostridium difficile infection | 53.02 | 13.20 | 67 | 392646 | 27131 | 55872223 |
Productive cough | 53.00 | 13.20 | 207 | 392506 | 56025 | 55843329 |
Eye swelling | 52.67 | 13.20 | 43 | 392670 | 21333 | 55878021 |
Hypersomnia | 52.62 | 13.20 | 24 | 392689 | 16317 | 55883037 |
Premature baby | 52.01 | 13.20 | 35 | 392678 | 19170 | 55880184 |
Shock | 51.95 | 13.20 | 45 | 392668 | 21683 | 55877671 |
Renal tubular necrosis | 51.90 | 13.20 | 7 | 392706 | 10821 | 55888533 |
Mean cell volume decreased | 51.13 | 13.20 | 89 | 392624 | 3379 | 55895975 |
Swollen tongue | 50.92 | 13.20 | 83 | 392630 | 30241 | 55869113 |
Back injury | 50.89 | 13.20 | 147 | 392566 | 7879 | 55891475 |
Nightmare | 50.72 | 13.20 | 27 | 392686 | 16799 | 55882555 |
Haemorrhoids | 50.59 | 13.20 | 40 | 392673 | 20166 | 55879188 |
Product label confusion | 50.54 | 13.20 | 48 | 392665 | 977 | 55898377 |
Throat tightness | 50.49 | 13.20 | 49 | 392664 | 22358 | 55876996 |
Retinitis | 50.44 | 13.20 | 99 | 392614 | 4125 | 55895229 |
Myopathy | 50.37 | 13.20 | 5 | 392708 | 9807 | 55889547 |
Device related infection | 50.29 | 13.20 | 47 | 392666 | 21833 | 55877521 |
Coronary artery disease | 50.13 | 13.20 | 86 | 392627 | 30710 | 55868644 |
Demyelination | 50.11 | 13.20 | 125 | 392588 | 6137 | 55893217 |
Multiple fractures | 50.02 | 13.20 | 138 | 392575 | 7203 | 55892151 |
Investigation abnormal | 49.96 | 13.20 | 61 | 392652 | 1667 | 55897687 |
General physical health deterioration | 49.71 | 13.20 | 1545 | 391168 | 168465 | 55730889 |
Ocular hyperaemia | 49.60 | 13.20 | 48 | 392665 | 21931 | 55877423 |
Sensitivity to weather change | 49.34 | 13.20 | 129 | 392584 | 6520 | 55892834 |
Cystitis | 49.17 | 13.20 | 176 | 392537 | 48862 | 55850492 |
Aspiration | 49.14 | 13.20 | 5 | 392708 | 9616 | 55889738 |
Underdose | 48.99 | 13.20 | 56 | 392657 | 23701 | 55875653 |
Infusion site reaction | 48.89 | 13.20 | 79 | 392634 | 2819 | 55896535 |
Supraventricular tachycardia | 48.62 | 13.20 | 16 | 392697 | 13275 | 55886079 |
Tricuspid valve incompetence | 48.40 | 13.20 | 16 | 392697 | 13237 | 55886117 |
Influenza | 48.32 | 13.20 | 428 | 392285 | 94833 | 55804521 |
Hyperbilirubinaemia | 48.15 | 13.20 | 7 | 392706 | 10228 | 55889126 |
Wheezing | 48.00 | 13.20 | 316 | 392397 | 74710 | 55824644 |
Acidosis | 47.55 | 13.20 | 8 | 392705 | 10493 | 55888861 |
Hypophosphataemia | 47.15 | 13.20 | 6 | 392707 | 9696 | 55889658 |
No adverse event | 46.98 | 13.20 | 116 | 392597 | 36258 | 55863096 |
Colitis ischaemic | 46.80 | 13.20 | 7 | 392706 | 10013 | 55889341 |
Retching | 46.57 | 13.20 | 18 | 392695 | 13512 | 55885842 |
Infusion site erythema | 46.54 | 13.20 | 6 | 392707 | 9600 | 55889754 |
Pharyngitis | 46.12 | 13.20 | 253 | 392460 | 18285 | 55881069 |
Bloody discharge | 46.11 | 13.20 | 54 | 392659 | 1411 | 55897943 |
Ventricular fibrillation | 46.08 | 13.20 | 10 | 392703 | 10942 | 55888412 |
Cardiomegaly | 45.97 | 13.20 | 29 | 392684 | 16438 | 55882916 |
Jaundice | 45.55 | 13.20 | 75 | 392638 | 27219 | 55872135 |
Blindness | 45.45 | 13.20 | 37 | 392676 | 18384 | 55880970 |
Pneumonia viral | 45.29 | 13.20 | 131 | 392582 | 7027 | 55892327 |
Wrist surgery | 45.22 | 13.20 | 41 | 392672 | 785 | 55898569 |
Hepatic encephalopathy | 45.12 | 13.20 | 8 | 392705 | 10102 | 55889252 |
Blood calcium increased | 45.06 | 13.20 | 3 | 392710 | 8151 | 55891203 |
Urine output decreased | 45.02 | 13.20 | 10 | 392703 | 10767 | 55888587 |
Synovial cyst | 44.84 | 13.20 | 154 | 392559 | 9060 | 55890294 |
Aplastic anaemia | 44.68 | 13.20 | 5 | 392708 | 8923 | 55890431 |
Bone density abnormal | 44.65 | 13.20 | 81 | 392632 | 3178 | 55896176 |
Anal incontinence | 44.64 | 13.20 | 15 | 392698 | 12283 | 55887071 |
Nasal congestion | 44.36 | 13.20 | 222 | 392491 | 56148 | 55843206 |
Fine motor skill dysfunction | 44.34 | 13.20 | 97 | 392616 | 4368 | 55894986 |
Gastric disorder | 44.30 | 13.20 | 389 | 392324 | 32821 | 55866533 |
Transaminases abnormal | 43.88 | 13.20 | 35 | 392678 | 558 | 55898796 |
Delusion | 43.75 | 13.20 | 12 | 392701 | 11203 | 55888151 |
Dactylitis | 43.73 | 13.20 | 63 | 392650 | 2029 | 55897325 |
Tumour lysis syndrome | 43.54 | 13.20 | 3 | 392710 | 7920 | 55891434 |
Infusion site swelling | 43.52 | 13.20 | 3 | 392710 | 7918 | 55891436 |
Stress cardiomyopathy | 43.45 | 13.20 | 4 | 392709 | 8332 | 55891022 |
Bronchitis | 43.34 | 13.20 | 538 | 392175 | 111773 | 55787581 |
Dermatitis atopic | 43.21 | 13.20 | 4 | 392709 | 8295 | 55891059 |
Toxic skin eruption | 43.17 | 13.20 | 14 | 392699 | 11725 | 55887629 |
Ear infection | 43.01 | 13.20 | 369 | 392344 | 30926 | 55868428 |
Myelodysplastic syndrome | 42.97 | 13.20 | 31 | 392682 | 16375 | 55882979 |
Acute respiratory distress syndrome | 42.75 | 13.20 | 54 | 392659 | 21872 | 55877482 |
Hip fracture | 42.39 | 13.20 | 77 | 392636 | 26896 | 55872458 |
Bronchitis chronic | 42.32 | 13.20 | 89 | 392624 | 3899 | 55895455 |
Abnormal dreams | 42.28 | 13.20 | 8 | 392705 | 9641 | 55889713 |
Migraine | 42.26 | 13.20 | 394 | 392319 | 86403 | 55812951 |
Lymphopenia | 42.26 | 13.20 | 33 | 392680 | 16741 | 55882613 |
Electrocardiogram abnormal | 42.21 | 13.20 | 4 | 392709 | 8140 | 55891214 |
Mental impairment | 42.04 | 13.20 | 18 | 392695 | 12704 | 55886650 |
Central nervous system lesion | 41.96 | 13.20 | 9 | 392704 | 9929 | 55889425 |
Myelosuppression | 41.91 | 13.20 | 36 | 392677 | 17419 | 55881935 |
Anti-cyclic citrullinated peptide antibody | 41.75 | 13.20 | 85 | 392628 | 3638 | 55895716 |
Ventricular extrasystoles | 41.72 | 13.20 | 12 | 392701 | 10858 | 55888496 |
Tardive dyskinesia | 41.47 | 13.20 | 4 | 392709 | 8027 | 55891327 |
Hepatocellular injury | 41.39 | 13.20 | 76 | 392637 | 26438 | 55872916 |
Mycotic allergy | 41.34 | 13.20 | 39 | 392674 | 787 | 55898567 |
Fear of injection | 40.99 | 13.20 | 119 | 392594 | 6396 | 55892958 |
Rash macular | 40.95 | 13.20 | 50 | 392663 | 20554 | 55878800 |
Colitis ulcerative | 40.73 | 13.20 | 67 | 392646 | 24324 | 55875030 |
Taste disorder | 40.61 | 13.20 | 9 | 392704 | 9706 | 55889648 |
Normal newborn | 40.55 | 13.20 | 3 | 392710 | 7467 | 55891887 |
Atelectasis | 40.37 | 13.20 | 45 | 392668 | 19263 | 55880091 |
Angina pectoris | 40.37 | 13.20 | 84 | 392629 | 27892 | 55871462 |
Cytomegalovirus infection | 40.32 | 13.20 | 45 | 392668 | 19251 | 55880103 |
Headache | 40.23 | 13.20 | 3356 | 389357 | 555688 | 55343666 |
Injection site mass | 39.88 | 13.20 | 35 | 392678 | 16758 | 55882596 |
Cutaneous vasculitis | 39.87 | 13.20 | 97 | 392616 | 4687 | 55894667 |
Renal injury | 39.73 | 13.20 | 7 | 392706 | 8880 | 55890474 |
Muscle tightness | 39.72 | 13.20 | 13 | 392700 | 10823 | 55888531 |
Urticarial vasculitis | 39.65 | 13.20 | 35 | 392678 | 646 | 55898708 |
Gait disturbance | 39.55 | 13.20 | 1452 | 391261 | 161869 | 55737485 |
Pre-eclampsia | 39.47 | 13.20 | 6 | 392707 | 8480 | 55890874 |
Joint arthroplasty | 39.47 | 13.20 | 68 | 392645 | 2560 | 55896794 |
Restless legs syndrome | 39.43 | 13.20 | 36 | 392677 | 16911 | 55882443 |
Throat irritation | 39.32 | 13.20 | 108 | 392605 | 32575 | 55866779 |
Frequent bowel movements | 39.28 | 13.20 | 34 | 392679 | 16390 | 55882964 |
Gestational diabetes | 39.16 | 13.20 | 5 | 392708 | 8059 | 55891295 |
Haemodynamic instability | 38.49 | 13.20 | 6 | 392707 | 8323 | 55891031 |
Apathy | 38.46 | 13.20 | 5 | 392708 | 7949 | 55891405 |
Hypotonia | 38.44 | 13.20 | 7 | 392706 | 8670 | 55890684 |
Interstitial lung disease | 38.32 | 13.20 | 585 | 392128 | 56478 | 55842876 |
Amenorrhoea | 38.22 | 13.20 | 8 | 392705 | 8978 | 55890376 |
Head discomfort | 38.13 | 13.20 | 18 | 392695 | 11996 | 55887358 |
Hyperlipidaemia | 38.09 | 13.20 | 42 | 392671 | 18067 | 55881287 |
Sensory loss | 37.91 | 13.20 | 8 | 392705 | 8927 | 55890427 |
Neck deformity | 37.83 | 13.20 | 58 | 392655 | 1977 | 55897377 |
Therapy non-responder | 37.80 | 13.20 | 620 | 392093 | 60735 | 55838619 |
Ovarian cyst | 37.76 | 13.20 | 29 | 392684 | 14837 | 55884517 |
White blood cell count increased | 37.71 | 13.20 | 172 | 392541 | 44587 | 55854767 |
Acute generalised exanthematous pustulosis | 37.68 | 13.20 | 11 | 392702 | 9858 | 55889496 |
Oesophagitis | 37.56 | 13.20 | 26 | 392687 | 14031 | 55885323 |
Onychomycosis | 37.53 | 13.20 | 116 | 392597 | 6456 | 55892898 |
Osteonecrosis of jaw | 37.38 | 13.20 | 114 | 392599 | 33244 | 55866110 |
Faeces discoloured | 37.34 | 13.20 | 38 | 392675 | 16958 | 55882396 |
Oliguria | 36.98 | 13.20 | 7 | 392706 | 8433 | 55890921 |
Tubulointerstitial nephritis | 36.91 | 13.20 | 37 | 392676 | 16628 | 55882726 |
Extremity contracture | 36.74 | 13.20 | 45 | 392668 | 1234 | 55898120 |
Bedridden | 36.59 | 13.20 | 156 | 392557 | 10169 | 55889185 |
Shock haemorrhagic | 36.51 | 13.20 | 9 | 392704 | 9024 | 55890330 |
Feeling cold | 36.51 | 13.20 | 57 | 392656 | 21130 | 55878224 |
Hypothyroidism | 36.38 | 13.20 | 140 | 392573 | 38056 | 55861298 |
Eosinophil count increased | 36.32 | 13.20 | 11 | 392702 | 9626 | 55889728 |
Chromaturia | 36.32 | 13.20 | 32 | 392681 | 15293 | 55884061 |
Pulmonary mass | 36.25 | 13.20 | 256 | 392457 | 20214 | 55879140 |
Troponin increased | 36.09 | 13.20 | 8 | 392705 | 8627 | 55890727 |
Lower gastrointestinal haemorrhage | 36.03 | 13.20 | 4 | 392709 | 7183 | 55892171 |
Atrioventricular block first degree | 35.93 | 13.20 | 3 | 392710 | 6762 | 55892592 |
Soft tissue disorder | 35.88 | 13.20 | 87 | 392626 | 4195 | 55895159 |
Haemodialysis | 35.83 | 13.20 | 8 | 392705 | 8583 | 55890771 |
Ovarian neoplasm | 35.60 | 13.20 | 37 | 392676 | 843 | 55898511 |
Hair follicle tumour benign | 35.59 | 13.20 | 26 | 392687 | 361 | 55898993 |
Influenza like illness | 35.51 | 13.20 | 264 | 392449 | 60724 | 55838630 |
Eyelid oedema | 35.31 | 13.20 | 12 | 392701 | 9756 | 55889598 |
Allergic oedema | 35.29 | 13.20 | 35 | 392678 | 753 | 55898601 |
Thyroid neoplasm | 34.97 | 13.20 | 80 | 392633 | 3713 | 55895641 |
Unevaluable event | 34.62 | 13.20 | 193 | 392520 | 47494 | 55851860 |
Coagulopathy | 34.54 | 13.20 | 48 | 392665 | 18668 | 55880686 |
Respiratory tract infection | 34.49 | 13.20 | 132 | 392581 | 35939 | 55863415 |
Pustular psoriasis | 34.38 | 13.20 | 88 | 392625 | 4390 | 55894964 |
Cholecystitis | 34.38 | 13.20 | 30 | 392683 | 14405 | 55884949 |
Back pain | 34.29 | 13.20 | 1330 | 391383 | 235840 | 55663514 |
Skin papilloma | 34.24 | 13.20 | 88 | 392625 | 4401 | 55894953 |
Atrioventricular block | 34.11 | 13.20 | 4 | 392709 | 6883 | 55892471 |
Device breakage | 34.10 | 13.20 | 14 | 392699 | 10133 | 55889221 |
Upper respiratory tract infection | 34.10 | 13.20 | 325 | 392388 | 70963 | 55828391 |
Blood loss anaemia | 34.05 | 13.20 | 8 | 392705 | 8289 | 55891065 |
Glomerular filtration rate decreased | 34.02 | 13.20 | 22 | 392691 | 12307 | 55887047 |
Apnoea | 33.96 | 13.20 | 5 | 392708 | 7237 | 55892117 |
Lupus-like syndrome | 33.92 | 13.20 | 174 | 392539 | 12253 | 55887101 |
Eructation | 33.88 | 13.20 | 6 | 392707 | 7582 | 55891772 |
Hereditary angioedema | 33.77 | 13.20 | 4 | 392709 | 6831 | 55892523 |
Rib fracture | 33.71 | 13.20 | 56 | 392657 | 20253 | 55879101 |
Sinus disorder | 33.65 | 13.20 | 58 | 392655 | 20676 | 55878678 |
Posterior reversible encephalopathy syndrome | 33.59 | 13.20 | 37 | 392676 | 15923 | 55883431 |
Device malfunction | 33.31 | 13.20 | 38 | 392675 | 16098 | 55883256 |
Hypermobility syndrome | 33.27 | 13.20 | 34 | 392679 | 759 | 55898595 |
Rhinitis allergic | 33.18 | 13.20 | 9 | 392704 | 8465 | 55890889 |
Epstein-Barr virus infection | 33.10 | 13.20 | 6 | 392707 | 7457 | 55891897 |
Skin laceration | 33.07 | 13.20 | 56 | 392657 | 20100 | 55879254 |
Mouth ulceration | 32.95 | 13.20 | 334 | 392379 | 29306 | 55870048 |
Pemphigoid | 32.90 | 13.20 | 3 | 392710 | 6297 | 55893057 |
Hemiplegia | 32.77 | 13.20 | 9 | 392704 | 8395 | 55890959 |
Infiltration anaesthesia | 32.73 | 13.20 | 19 | 392694 | 173 | 55899181 |
Hyperthyroidism | 32.72 | 13.20 | 27 | 392686 | 13325 | 55886029 |
Peripheral coldness | 32.70 | 13.20 | 18 | 392695 | 10993 | 55888361 |
Neuralgia | 32.65 | 13.20 | 73 | 392640 | 23622 | 55875732 |
Mean cell haemoglobin decreased | 32.62 | 13.20 | 85 | 392628 | 4287 | 55895067 |
Femur fracture | 32.50 | 13.20 | 418 | 392295 | 38877 | 55860477 |
Dermatitis contact | 32.26 | 13.20 | 13 | 392700 | 9514 | 55889840 |
Mycobacterium tuberculosis complex test positive | 32.24 | 13.20 | 53 | 392660 | 1919 | 55897435 |
Anticipatory anxiety | 32.12 | 13.20 | 38 | 392675 | 1004 | 55898350 |
Acute coronary syndrome | 31.99 | 13.20 | 14 | 392699 | 9754 | 55889600 |
Vasculitic rash | 31.96 | 13.20 | 42 | 392671 | 1238 | 55898116 |
Musculoskeletal chest pain | 31.83 | 13.20 | 55 | 392658 | 19586 | 55879768 |
Polyarthritis | 31.81 | 13.20 | 133 | 392580 | 8595 | 55890759 |
Atrial septal defect | 31.67 | 13.20 | 4 | 392709 | 6502 | 55892852 |
End stage renal disease | 31.67 | 13.20 | 3 | 392710 | 6108 | 55893246 |
Haemolytic anaemia | 31.53 | 13.20 | 14 | 392699 | 9671 | 55889683 |
Mood altered | 31.51 | 13.20 | 28 | 392685 | 13327 | 55886027 |
Polyomavirus-associated nephropathy | 31.46 | 13.20 | 48 | 392665 | 1629 | 55897725 |
Injection site erythema | 31.40 | 13.20 | 367 | 392346 | 77081 | 55822273 |
Alanine aminotransferase abnormal | 31.29 | 13.20 | 83 | 392630 | 4232 | 55895122 |
Menstruation irregular | 30.98 | 13.20 | 4 | 392709 | 6392 | 55892962 |
Blood triglycerides increased | 30.67 | 13.20 | 22 | 392691 | 11655 | 55887699 |
Pre-existing condition improved | 30.63 | 13.20 | 7 | 392706 | 7391 | 55891963 |
Toxic encephalopathy | 30.55 | 13.20 | 3 | 392710 | 5935 | 55893419 |
Heavy menstrual bleeding | 30.49 | 13.20 | 41 | 392672 | 16168 | 55883186 |
Seasonal allergy | 30.47 | 13.20 | 45 | 392668 | 17063 | 55882291 |
Lymphadenopathy | 30.44 | 13.20 | 134 | 392579 | 35074 | 55864280 |
Flank pain | 30.38 | 13.20 | 33 | 392680 | 14292 | 55885062 |
Thirst | 30.32 | 13.20 | 20 | 392693 | 11070 | 55888284 |
Motor dysfunction | 30.28 | 13.20 | 14 | 392699 | 9443 | 55889911 |
Atrial flutter | 30.26 | 13.20 | 13 | 392700 | 9156 | 55890198 |
Drug resistance | 30.22 | 13.20 | 61 | 392652 | 20481 | 55878873 |
Bradyphrenia | 30.07 | 13.20 | 5 | 392708 | 6615 | 55892739 |
Hypoacusis | 30.05 | 13.20 | 67 | 392646 | 21701 | 55877653 |
Sensory disturbance | 29.96 | 13.20 | 26 | 392687 | 12517 | 55886837 |
Food allergy | 29.94 | 13.20 | 12 | 392701 | 8812 | 55890542 |
Contusion | 29.92 | 13.20 | 1137 | 391576 | 127293 | 55772061 |
Thinking abnormal | 29.89 | 13.20 | 16 | 392697 | 9925 | 55889429 |
Acute pulmonary oedema | 29.88 | 13.20 | 8 | 392705 | 7589 | 55891765 |
Nystagmus | 29.82 | 13.20 | 3 | 392710 | 5822 | 55893532 |
Procedural pain | 29.76 | 13.20 | 42 | 392671 | 16229 | 55883125 |
Failure to thrive | 29.76 | 13.20 | 5 | 392708 | 6565 | 55892789 |
Gastroenteritis viral | 29.74 | 13.20 | 61 | 392652 | 20363 | 55878991 |
Labile blood pressure | 29.73 | 13.20 | 47 | 392666 | 1646 | 55897708 |
Immune thrombocytopenia | 29.67 | 13.20 | 15 | 392698 | 9610 | 55889744 |
Sudden death | 29.67 | 13.20 | 15 | 392698 | 9610 | 55889744 |
Walking aid user | 29.48 | 13.20 | 127 | 392586 | 8316 | 55891038 |
Immobile | 29.48 | 13.20 | 95 | 392618 | 5407 | 55893947 |
Increased appetite | 29.44 | 13.20 | 12 | 392701 | 8723 | 55890631 |
Injection site haemorrhage | 29.30 | 13.20 | 70 | 392643 | 22131 | 55877223 |
Hypercholesterolaemia | 29.23 | 13.20 | 187 | 392526 | 14286 | 55885068 |
Angina unstable | 29.16 | 13.20 | 6 | 392707 | 6815 | 55892539 |
Neutrophil count increased | 29.03 | 13.20 | 37 | 392676 | 14928 | 55884426 |
Generalised oedema | 29.02 | 13.20 | 35 | 392678 | 14466 | 55884888 |
Disease susceptibility | 29.02 | 13.20 | 18 | 392695 | 187 | 55899167 |
Pulmonary haemorrhage | 28.93 | 13.20 | 6 | 392707 | 6777 | 55892577 |
Spinal stenosis | 28.88 | 13.20 | 182 | 392531 | 13832 | 55885522 |
Nocturia | 28.87 | 13.20 | 7 | 392706 | 7099 | 55892255 |
Blood lactic acid increased | 28.87 | 13.20 | 4 | 392709 | 6060 | 55893294 |
Foetal growth restriction | 28.83 | 13.20 | 7 | 392706 | 7092 | 55892262 |
Lymphoedema | 28.77 | 13.20 | 19 | 392694 | 10511 | 55888843 |
Cardiomyopathy | 28.72 | 13.20 | 43 | 392670 | 16215 | 55883139 |
Drug level decreased | 28.62 | 13.20 | 7 | 392706 | 7057 | 55892297 |
Dialysis | 28.61 | 13.20 | 16 | 392697 | 9686 | 55889668 |
Progressive multifocal leukoencephalopathy | 28.57 | 13.20 | 25 | 392688 | 11988 | 55887366 |
Staphylococcal infection | 28.55 | 13.20 | 150 | 392563 | 37468 | 55861886 |
Fistula | 28.52 | 13.20 | 13 | 392700 | 8842 | 55890512 |
Hepatitis | 28.47 | 13.20 | 375 | 392338 | 35066 | 55864288 |
Oedema | 28.46 | 13.20 | 401 | 392312 | 81519 | 55817835 |
Haematocrit decreased | 28.43 | 13.20 | 146 | 392567 | 36683 | 55862671 |
Osteoporotic fracture | 28.39 | 13.20 | 68 | 392645 | 3253 | 55896101 |
Impaired gastric emptying | 28.35 | 13.20 | 134 | 392579 | 9129 | 55890225 |
Heart rate irregular | 28.26 | 13.20 | 64 | 392649 | 20615 | 55878739 |
Escherichia infection | 28.25 | 13.20 | 24 | 392689 | 11675 | 55887679 |
Spinal compression fracture | 28.14 | 13.20 | 30 | 392683 | 13104 | 55886250 |
Prothrombin time prolonged | 28.11 | 13.20 | 14 | 392699 | 9046 | 55890308 |
Major depression | 27.97 | 13.20 | 9 | 392704 | 7575 | 55891779 |
Bipolar disorder | 27.95 | 13.20 | 9 | 392704 | 7571 | 55891783 |
Purpura | 27.90 | 13.20 | 19 | 392694 | 10343 | 55889011 |
Hypoalbuminaemia | 27.80 | 13.20 | 20 | 392693 | 10579 | 55888775 |
Subarachnoid haemorrhage | 27.74 | 13.20 | 23 | 392690 | 11324 | 55888030 |
Suspected suicide | 27.51 | 13.20 | 3 | 392710 | 5463 | 55893891 |
Product storage error | 27.40 | 13.20 | 31 | 392682 | 13182 | 55886172 |
Functional gastrointestinal disorder | 27.37 | 13.20 | 73 | 392640 | 3734 | 55895620 |
Blood albumin decreased | 27.16 | 13.20 | 33 | 392680 | 13595 | 55885759 |
Cerebral ischaemia | 27.16 | 13.20 | 5 | 392708 | 6145 | 55893209 |
Injection site swelling | 27.14 | 13.20 | 185 | 392528 | 43393 | 55855961 |
Lung neoplasm malignant | 27.03 | 13.20 | 50 | 392663 | 17346 | 55882008 |
Myocarditis | 27.01 | 13.20 | 14 | 392699 | 8844 | 55890510 |
Cold sweat | 26.97 | 13.20 | 22 | 392691 | 10921 | 55888433 |
Granulocytopenia | 26.72 | 13.20 | 3 | 392710 | 5341 | 55894013 |
Nephropathy toxic | 26.72 | 13.20 | 13 | 392700 | 8514 | 55890840 |
Hiatus hernia | 26.71 | 13.20 | 61 | 392652 | 19591 | 55879763 |
Hepatitis cholestatic | 26.69 | 13.20 | 6 | 392707 | 6408 | 55892946 |
Hypercalcaemia | 26.66 | 13.20 | 283 | 392430 | 25128 | 55874226 |
Petechiae | 26.60 | 13.20 | 31 | 392682 | 13008 | 55886346 |
Infusion site extravasation | 26.52 | 13.20 | 12 | 392701 | 8198 | 55891156 |
Skin reaction | 26.51 | 13.20 | 169 | 392544 | 12894 | 55886460 |
Mass excision | 26.48 | 13.20 | 20 | 392693 | 293 | 55899061 |
Rhinorrhoea | 26.45 | 13.20 | 262 | 392451 | 56775 | 55842579 |
Brain injury | 26.34 | 13.20 | 6 | 392707 | 6349 | 55893005 |
Ankle deformity | 26.21 | 13.20 | 23 | 392690 | 421 | 55898933 |
Ageusia | 26.05 | 13.20 | 29 | 392684 | 12422 | 55886932 |
White blood cell count abnormal | 25.93 | 13.20 | 95 | 392618 | 5772 | 55893582 |
Vascular device infection | 25.89 | 13.20 | 4 | 392709 | 5586 | 55893768 |
Poor quality sleep | 25.88 | 13.20 | 53 | 392660 | 17702 | 55881652 |
Arteriosclerosis coronary artery | 25.86 | 13.20 | 11 | 392702 | 7794 | 55891560 |
Hypoaesthesia oral | 25.75 | 13.20 | 25 | 392688 | 11406 | 55887948 |
Unintended pregnancy | 25.74 | 13.20 | 3 | 392710 | 5188 | 55894166 |
Injection site reaction | 25.74 | 13.20 | 518 | 392195 | 52729 | 55846625 |
Myocardial ischaemia | 25.59 | 13.20 | 28 | 392685 | 12088 | 55887266 |
Pelvic pain | 25.54 | 13.20 | 27 | 392686 | 11840 | 55887514 |
Hyperthermia | 25.41 | 13.20 | 13 | 392700 | 8272 | 55891082 |
Exercise tolerance decreased | 25.40 | 13.20 | 3 | 392710 | 5135 | 55894219 |
Enterocolitis | 25.21 | 13.20 | 9 | 392704 | 7095 | 55892259 |
Extra dose administered | 25.16 | 13.20 | 4 | 392709 | 5469 | 55893885 |
Psychomotor hyperactivity | 25.14 | 13.20 | 19 | 392694 | 9801 | 55889553 |
Personality change | 25.11 | 13.20 | 5 | 392708 | 5812 | 55893542 |
Erythema multiforme | 25.09 | 13.20 | 18 | 392695 | 9536 | 55889818 |
Heart rate decreased | 24.99 | 13.20 | 172 | 392541 | 40255 | 55859099 |
Secretion discharge | 24.95 | 13.20 | 142 | 392571 | 10404 | 55888950 |
Joint space narrowing | 24.92 | 13.20 | 21 | 392692 | 363 | 55898991 |
Salivary hypersecretion | 24.90 | 13.20 | 9 | 392704 | 7041 | 55892313 |
Localised oedema | 24.58 | 13.20 | 3 | 392710 | 5006 | 55894348 |
Scleroderma | 24.53 | 13.20 | 3 | 392710 | 4998 | 55894356 |
Upper-airway cough syndrome | 24.50 | 13.20 | 18 | 392695 | 9420 | 55889934 |
Glycosylated haemoglobin increased | 24.48 | 13.20 | 25 | 392688 | 11140 | 55888214 |
Bundle branch block left | 24.46 | 13.20 | 7 | 392706 | 6355 | 55892999 |
Hepatic cytolysis | 24.40 | 13.20 | 24 | 392689 | 10882 | 55888472 |
Allergy to chemicals | 24.32 | 13.20 | 53 | 392660 | 2380 | 55896974 |
Oral discomfort | 24.23 | 13.20 | 119 | 392594 | 8236 | 55891118 |
Hypoaesthesia | 24.19 | 13.20 | 777 | 391936 | 140714 | 55758640 |
Photophobia | 24.18 | 13.20 | 47 | 392666 | 16003 | 55883351 |
Oligohydramnios | 24.17 | 13.20 | 6 | 392707 | 5988 | 55893366 |
Colitis microscopic | 24.16 | 13.20 | 114 | 392599 | 7761 | 55891593 |
Hyperventilation | 24.08 | 13.20 | 5 | 392708 | 5643 | 55893711 |
Klebsiella infection | 24.04 | 13.20 | 12 | 392701 | 7744 | 55891610 |
Polyp | 23.86 | 13.20 | 6 | 392707 | 5936 | 55893418 |
Concussion | 23.75 | 13.20 | 14 | 392699 | 8232 | 55891122 |
Mean cell haemoglobin concentration abnormal | 23.70 | 13.20 | 13 | 392700 | 105 | 55899249 |
Eyelid ptosis | 23.58 | 13.20 | 8 | 392705 | 6511 | 55892843 |
Eye irritation | 23.55 | 13.20 | 62 | 392651 | 18966 | 55880388 |
Intestinal sepsis | 23.53 | 13.20 | 18 | 392695 | 269 | 55899085 |
Lipase increased | 23.47 | 13.20 | 17 | 392696 | 8962 | 55890392 |
Bacterial infection | 23.38 | 13.20 | 54 | 392659 | 17276 | 55882078 |
Fracture delayed union | 23.23 | 13.20 | 51 | 392662 | 2302 | 55897052 |
Dental caries | 23.18 | 13.20 | 22 | 392691 | 10146 | 55889208 |
Injection site hypersensitivity | 23.18 | 13.20 | 45 | 392668 | 1860 | 55897494 |
Drug tolerance | 23.16 | 13.20 | 93 | 392620 | 5901 | 55893453 |
Metastasis | 23.15 | 13.20 | 3 | 392710 | 4781 | 55894573 |
Intermenstrual bleeding | 23.13 | 13.20 | 10 | 392703 | 7017 | 55892337 |
Refusal of treatment by patient | 23.07 | 13.20 | 4 | 392709 | 5134 | 55894220 |
Diabetic eye disease | 23.02 | 13.20 | 14 | 392699 | 140 | 55899214 |
Asphyxia | 22.95 | 13.20 | 6 | 392707 | 5783 | 55893571 |
Acute hepatic failure | 22.90 | 13.20 | 51 | 392662 | 16527 | 55882827 |
Peritonitis bacterial | 22.83 | 13.20 | 3 | 392710 | 4730 | 55894624 |
Accident | 22.81 | 13.20 | 87 | 392626 | 5389 | 55893965 |
Dry throat | 22.77 | 13.20 | 7 | 392706 | 6067 | 55893287 |
Illness | 22.76 | 13.20 | 144 | 392569 | 34367 | 55864987 |
Blood pressure systolic decreased | 22.57 | 13.20 | 8 | 392705 | 6335 | 55893019 |
Nail disorder | 22.54 | 13.20 | 147 | 392566 | 11304 | 55888050 |
Anger | 22.49 | 13.20 | 29 | 392684 | 11643 | 55887711 |
Menstrual disorder | 22.46 | 13.20 | 3 | 392710 | 4672 | 55894682 |
Localised infection | 22.42 | 13.20 | 291 | 392422 | 27121 | 55872233 |
Weight increased | 22.37 | 13.20 | 1877 | 390836 | 227826 | 55671528 |
Choking | 22.29 | 13.20 | 18 | 392695 | 8979 | 55890375 |
Needle issue | 22.25 | 13.20 | 17 | 392696 | 8721 | 55890633 |
Metastases to lymph nodes | 22.24 | 13.20 | 12 | 392701 | 7411 | 55891943 |
Impaired quality of life | 22.21 | 13.20 | 16 | 392697 | 8458 | 55890896 |
Rash papular | 22.12 | 13.20 | 37 | 392676 | 13346 | 55886008 |
Arteriosclerosis | 22.09 | 13.20 | 20 | 392693 | 9433 | 55889921 |
Neck mass | 22.03 | 13.20 | 63 | 392650 | 3357 | 55895997 |
Proteinuria | 21.94 | 13.20 | 57 | 392656 | 17513 | 55881841 |
Middle lobe syndrome | 21.91 | 13.20 | 9 | 392704 | 34 | 55899320 |
Product complaint | 21.86 | 13.20 | 30 | 392683 | 11730 | 55887624 |
Osteomyelitis | 21.86 | 13.20 | 263 | 392450 | 24083 | 55875271 |
Expired product administered | 21.84 | 13.20 | 6 | 392707 | 5596 | 55893758 |
Systemic inflammatory response syndrome | 21.84 | 13.20 | 5 | 392708 | 5273 | 55894081 |
Lung infiltration | 21.78 | 13.20 | 39 | 392674 | 13699 | 55885655 |
Acne | 21.76 | 13.20 | 75 | 392638 | 21061 | 55878293 |
Appendicitis | 21.75 | 13.20 | 12 | 392701 | 7320 | 55892034 |
Large intestine perforation | 21.68 | 13.20 | 14 | 392699 | 7837 | 55891517 |
Intracranial pressure increased | 21.64 | 13.20 | 3 | 392710 | 4542 | 55894812 |
Pneumonia fungal | 21.56 | 13.20 | 4 | 392709 | 4889 | 55894465 |
Hepatic ischaemia | 21.52 | 13.20 | 24 | 392689 | 594 | 55898760 |
Sneezing | 21.39 | 13.20 | 48 | 392665 | 15512 | 55883842 |
Congestive cardiomyopathy | 21.29 | 13.20 | 7 | 392706 | 5812 | 55893542 |
Bronchopulmonary aspergillosis | 21.15 | 13.20 | 16 | 392697 | 8248 | 55891106 |
Device leakage | 21.10 | 13.20 | 9 | 392704 | 6366 | 55892988 |
Fungal infection | 21.08 | 13.20 | 139 | 392574 | 32854 | 55866500 |
Blood alkaline phosphatase increased | 21.07 | 13.20 | 172 | 392541 | 38773 | 55860581 |
Wrist fracture | 21.06 | 13.20 | 32 | 392681 | 11994 | 55887360 |
Respiratory rate increased | 21.01 | 13.20 | 33 | 392680 | 12204 | 55887150 |
Extrasystoles | 20.98 | 13.20 | 4 | 392709 | 4795 | 55894559 |
Splenomegaly | 20.93 | 13.20 | 24 | 392689 | 10144 | 55889210 |
Enteritis | 20.92 | 13.20 | 13 | 392700 | 7430 | 55891924 |
Eye movement disorder | 20.92 | 13.20 | 4 | 392709 | 4785 | 55894569 |
Limb operation | 20.92 | 13.20 | 64 | 392649 | 3542 | 55895812 |
Activated partial thromboplastin time prolonged | 20.84 | 13.20 | 10 | 392703 | 6602 | 55892752 |
Rales | 20.82 | 13.20 | 27 | 392686 | 10813 | 55888541 |
Spinal meningioma benign | 20.70 | 13.20 | 12 | 392701 | 109 | 55899245 |
Concomitant disease aggravated | 20.69 | 13.20 | 17 | 392696 | 8409 | 55890945 |
Bone disorder | 20.67 | 13.20 | 218 | 392495 | 19325 | 55880029 |
Dry mouth | 20.66 | 13.20 | 319 | 392394 | 63886 | 55835468 |
Treatment noncompliance | 20.56 | 13.20 | 138 | 392575 | 32485 | 55866869 |
Lyme disease | 20.54 | 13.20 | 56 | 392657 | 2902 | 55896452 |
Brain natriuretic peptide increased | 20.53 | 13.20 | 4 | 392709 | 4722 | 55894632 |
Embolism | 20.51 | 13.20 | 13 | 392700 | 7351 | 55892003 |
Ear discomfort | 20.50 | 13.20 | 12 | 392701 | 7083 | 55892271 |
Cardiac failure acute | 20.46 | 13.20 | 19 | 392694 | 8854 | 55890500 |
Upper limb fracture | 20.40 | 13.20 | 57 | 392656 | 17098 | 55882256 |
Limb injury | 20.34 | 13.20 | 83 | 392630 | 22187 | 55877167 |
Osteonecrosis | 20.28 | 13.20 | 88 | 392625 | 23127 | 55876227 |
Wound infection | 20.28 | 13.20 | 178 | 392535 | 15015 | 55884339 |
Respiration abnormal | 20.27 | 13.20 | 7 | 392706 | 5634 | 55893720 |
Dizziness postural | 20.22 | 13.20 | 10 | 392703 | 6488 | 55892866 |
Aortic arteriosclerosis | 20.21 | 13.20 | 7 | 392706 | 5623 | 55893731 |
Drug level below therapeutic | 20.17 | 13.20 | 3 | 392710 | 4310 | 55895044 |
Forced expiratory volume decreased | 20.13 | 13.20 | 4 | 392709 | 4656 | 55894698 |
Aortic valve incompetence | 20.10 | 13.20 | 7 | 392706 | 5605 | 55893749 |
Blood potassium increased | 20.05 | 13.20 | 58 | 392655 | 17203 | 55882151 |
Tumour marker increased | 20.05 | 13.20 | 3 | 392710 | 4290 | 55895064 |
Vitreous floaters | 19.84 | 13.20 | 7 | 392706 | 5560 | 55893794 |
Crohn's disease | 19.83 | 13.20 | 10 | 392703 | 6417 | 55892937 |
Hyperammonaemia | 19.81 | 13.20 | 5 | 392708 | 4935 | 55894419 |
Rheumatoid factor | 19.66 | 13.20 | 10 | 392703 | 68 | 55899286 |
Lower limb fracture | 19.65 | 13.20 | 199 | 392514 | 17456 | 55881898 |
Sinus congestion | 19.64 | 13.20 | 51 | 392662 | 15673 | 55883681 |
Skin irritation | 19.62 | 13.20 | 18 | 392695 | 8437 | 55890917 |
Rheumatic disorder | 19.61 | 13.20 | 48 | 392665 | 2328 | 55897026 |
Hypertriglyceridaemia | 19.59 | 13.20 | 8 | 392705 | 5808 | 55893546 |
Jaundice cholestatic | 19.57 | 13.20 | 7 | 392706 | 5512 | 55893842 |
Arthritis bacterial | 19.55 | 13.20 | 88 | 392625 | 5873 | 55893481 |
Abscess | 19.55 | 13.20 | 48 | 392665 | 15033 | 55884321 |
International normalised ratio decreased | 19.44 | 13.20 | 3 | 392710 | 4193 | 55895161 |
Post procedural complication | 19.42 | 13.20 | 51 | 392662 | 15615 | 55883739 |
Bowel movement irregularity | 19.29 | 13.20 | 4 | 392709 | 4519 | 55894835 |
Metabolic disorder | 19.24 | 13.20 | 7 | 392706 | 5454 | 55893900 |
Red blood cell count decreased | 19.23 | 13.20 | 163 | 392550 | 36454 | 55862900 |
Invasive ductal breast carcinoma | 19.08 | 13.20 | 12 | 392701 | 6814 | 55892540 |
Odynophagia | 19.04 | 13.20 | 12 | 392701 | 6806 | 55892548 |
Infusion site pruritus | 19.02 | 13.20 | 5 | 392708 | 4802 | 55894552 |
Supraventricular extrasystoles | 18.96 | 13.20 | 3 | 392710 | 4117 | 55895237 |
Micturition urgency | 18.87 | 13.20 | 20 | 392693 | 8761 | 55890593 |
Hepatomegaly | 18.80 | 13.20 | 31 | 392682 | 11244 | 55888110 |
Hypertonia | 18.79 | 13.20 | 3 | 392710 | 4089 | 55895265 |
Internal haemorrhage | 18.77 | 13.20 | 5 | 392708 | 4759 | 55894595 |
Hypovolaemic shock | 18.74 | 13.20 | 7 | 392706 | 5366 | 55893988 |
Diffuse large B-cell lymphoma | 18.71 | 13.20 | 13 | 392700 | 7003 | 55892351 |
Stillbirth | 18.69 | 13.20 | 10 | 392703 | 6204 | 55893150 |
Diastolic dysfunction | 18.63 | 13.20 | 8 | 392705 | 5637 | 55893717 |
Cellulitis gangrenous | 18.61 | 13.20 | 9 | 392704 | 54 | 55899300 |
Drug-induced liver injury | 18.61 | 13.20 | 341 | 392372 | 34121 | 55865233 |
Live birth | 18.58 | 13.20 | 214 | 392499 | 19391 | 55879963 |
Hepatic fibrosis | 18.49 | 13.20 | 58 | 392655 | 3254 | 55896100 |
Urine analysis abnormal | 18.49 | 13.20 | 5 | 392708 | 4712 | 55894642 |
Rash maculo-papular | 18.36 | 13.20 | 122 | 392591 | 28785 | 55870569 |
Hepatic enzyme abnormal | 18.35 | 13.20 | 78 | 392635 | 5077 | 55894277 |
Ocular toxicity | 18.35 | 13.20 | 23 | 392690 | 646 | 55898708 |
Drug level above therapeutic | 18.32 | 13.20 | 4 | 392709 | 4358 | 55894996 |
Serum ferritin increased | 18.19 | 13.20 | 8 | 392705 | 5557 | 55893797 |
Cholecystitis acute | 18.17 | 13.20 | 15 | 392698 | 7401 | 55891953 |
Chronic sinusitis | 18.10 | 13.20 | 19 | 392694 | 8359 | 55890995 |
Orthopnoea | 18.02 | 13.20 | 9 | 392704 | 5807 | 55893547 |
Vitamin D deficiency | 18.02 | 13.20 | 36 | 392677 | 12134 | 55887220 |
Pneumothorax | 17.98 | 13.20 | 49 | 392664 | 14818 | 55884536 |
Uterine leiomyoma | 17.93 | 13.20 | 19 | 392694 | 8323 | 55891031 |
Soft tissue swelling | 17.92 | 13.20 | 29 | 392684 | 1036 | 55898318 |
Diverticulum | 17.92 | 13.20 | 31 | 392682 | 11035 | 55888319 |
Humerus fracture | 17.90 | 13.20 | 18 | 392695 | 8079 | 55891275 |
Incorrect dosage administered | 17.89 | 13.20 | 39 | 392674 | 1752 | 55897602 |
Glucose tolerance impaired | 17.86 | 13.20 | 8 | 392705 | 5497 | 55893857 |
Eye pruritus | 17.80 | 13.20 | 46 | 392667 | 14160 | 55885194 |
Spinal fracture | 17.79 | 13.20 | 57 | 392656 | 16367 | 55882987 |
Drug use disorder | 17.69 | 13.20 | 72 | 392641 | 4597 | 55894757 |
Affect lability | 17.67 | 13.20 | 27 | 392686 | 10098 | 55889256 |
Polyuria | 17.61 | 13.20 | 16 | 392697 | 7535 | 55891819 |
Overwork | 17.59 | 13.20 | 9 | 392704 | 62 | 55899292 |
Salt craving | 17.51 | 13.20 | 10 | 392703 | 88 | 55899266 |
Breast pain | 17.42 | 13.20 | 18 | 392695 | 7976 | 55891378 |
Laboratory test abnormal | 17.35 | 13.20 | 101 | 392612 | 24594 | 55874760 |
Ileus paralytic | 17.31 | 13.20 | 4 | 392709 | 4191 | 55895163 |
Exposure during pregnancy | 17.30 | 13.20 | 1138 | 391575 | 135204 | 55764150 |
Blood glucose abnormal | 17.24 | 13.20 | 15 | 392698 | 7213 | 55892141 |
Bronchospasm | 17.23 | 13.20 | 54 | 392659 | 15615 | 55883739 |
Bladder cancer | 17.23 | 13.20 | 6 | 392707 | 4804 | 55894550 |
Heart rate abnormal | 17.23 | 13.20 | 5 | 392708 | 4498 | 55894856 |
Colon cancer | 17.17 | 13.20 | 25 | 392688 | 9536 | 55889818 |
Pain of skin | 17.16 | 13.20 | 21 | 392692 | 8625 | 55890729 |
Maternal drugs affecting foetus | 17.16 | 13.20 | 7 | 392706 | 5086 | 55894268 |
Urine abnormality | 17.10 | 13.20 | 13 | 392700 | 6686 | 55892668 |
Gastroenteritis | 17.07 | 13.20 | 100 | 392613 | 24312 | 55875042 |
Steatohepatitis | 17.04 | 13.20 | 19 | 392694 | 470 | 55898884 |
Enterococcal infection | 17.03 | 13.20 | 15 | 392698 | 7169 | 55892185 |
Enthesophyte | 17.01 | 13.20 | 6 | 392707 | 13 | 55899341 |
Premature rupture of membranes | 16.97 | 13.20 | 6 | 392707 | 4759 | 55894595 |
Ventricular septal defect | 16.96 | 13.20 | 4 | 392709 | 4134 | 55895220 |
Product residue present | 16.94 | 13.20 | 3 | 392710 | 3792 | 55895562 |
Skin burning sensation | 16.88 | 13.20 | 32 | 392681 | 10999 | 55888355 |
Spinal cord compression | 16.88 | 13.20 | 3 | 392710 | 3781 | 55895573 |
Scratch | 16.87 | 13.20 | 9 | 392704 | 5594 | 55893760 |
Decreased activity | 16.84 | 13.20 | 9 | 392704 | 5587 | 55893767 |
Paralysis | 16.83 | 13.20 | 23 | 392690 | 9009 | 55890345 |
Gingival pain | 16.82 | 13.20 | 12 | 392701 | 6376 | 55892978 |
Cardiac tamponade | 16.78 | 13.20 | 5 | 392708 | 4421 | 55894933 |
Hydronephrosis | 16.76 | 13.20 | 24 | 392689 | 9218 | 55890136 |
Photopsia | 16.75 | 13.20 | 4 | 392709 | 4099 | 55895255 |
Prescribed overdose | 16.71 | 13.20 | 233 | 392480 | 22063 | 55877291 |
Amyotrophic lateral sclerosis | 16.70 | 13.20 | 29 | 392684 | 1099 | 55898255 |
Visual field defect | 16.62 | 13.20 | 11 | 392702 | 6078 | 55893276 |
Ketoacidosis | 16.59 | 13.20 | 4 | 392709 | 4071 | 55895283 |
Dermatitis bullous | 16.56 | 13.20 | 17 | 392696 | 7556 | 55891798 |
Middle insomnia | 16.55 | 13.20 | 32 | 392681 | 10918 | 55888436 |
Muscle relaxant therapy | 16.52 | 13.20 | 12 | 392701 | 165 | 55899189 |
Haemolysis | 16.52 | 13.20 | 12 | 392701 | 6316 | 55893038 |
Pseudomonas infection | 16.50 | 13.20 | 28 | 392685 | 10043 | 55889311 |
Tendonitis | 16.47 | 13.20 | 196 | 392517 | 17901 | 55881453 |
Bladder disorder | 16.45 | 13.20 | 19 | 392694 | 8005 | 55891349 |
Blood culture positive | 16.31 | 13.20 | 5 | 392708 | 4341 | 55895013 |
Intervertebral disc space narrowing | 16.27 | 13.20 | 26 | 392687 | 919 | 55898435 |
Facet joint syndrome | 16.26 | 13.20 | 91 | 392622 | 6626 | 55892728 |
Breast cancer female | 16.20 | 13.20 | 39 | 392674 | 12299 | 55887055 |
C-reactive protein | 16.10 | 13.20 | 40 | 392673 | 1959 | 55897395 |
Arteriospasm coronary | 16.03 | 13.20 | 3 | 392710 | 3644 | 55895710 |
Maternal exposure during breast feeding | 16.03 | 13.20 | 3 | 392710 | 3644 | 55895710 |
Multiple-drug resistance | 15.98 | 13.20 | 4 | 392709 | 3970 | 55895384 |
Oxygen consumption increased | 15.93 | 13.20 | 3 | 392710 | 3628 | 55895726 |
Transplant rejection | 15.93 | 13.20 | 28 | 392685 | 9906 | 55889448 |
Drug dependence | 15.92 | 13.20 | 92 | 392621 | 22441 | 55876913 |
Catheterisation cardiac | 15.90 | 13.20 | 5 | 392708 | 4270 | 55895084 |
Deep vein thrombosis postoperative | 15.85 | 13.20 | 63 | 392650 | 3978 | 55895376 |
Immune reconstitution inflammatory syndrome | 15.83 | 13.20 | 10 | 392703 | 5664 | 55893690 |
Oral mucosal blistering | 15.83 | 13.20 | 8 | 392705 | 5126 | 55894228 |
Haemorrhagic stroke | 15.80 | 13.20 | 9 | 392704 | 5394 | 55893960 |
Inflammatory marker increased | 15.75 | 13.20 | 84 | 392629 | 6006 | 55893348 |
Snoring | 15.62 | 13.20 | 3 | 392710 | 3578 | 55895776 |
Gallbladder disorder | 15.58 | 13.20 | 65 | 392648 | 17269 | 55882085 |
Maternal exposure timing unspecified | 15.55 | 13.20 | 77 | 392636 | 5346 | 55894008 |
Injection site bruising | 15.43 | 13.20 | 183 | 392530 | 38338 | 55861016 |
Abnormal faeces | 15.35 | 13.20 | 7 | 392706 | 4761 | 55894593 |
Hepatic necrosis | 15.34 | 13.20 | 9 | 392704 | 5307 | 55894047 |
Culture urine positive | 15.30 | 13.20 | 3 | 392710 | 3525 | 55895829 |
Dermatitis exfoliative | 15.25 | 13.20 | 9 | 392704 | 5290 | 55894064 |
Blood thyroid stimulating hormone increased | 15.20 | 13.20 | 14 | 392699 | 6549 | 55892805 |
Anxiety disorder | 15.06 | 13.20 | 4 | 392709 | 3816 | 55895538 |
Thrombophlebitis | 15.04 | 13.20 | 5 | 392708 | 4122 | 55895232 |
Mass | 15.02 | 13.20 | 43 | 392670 | 12796 | 55886558 |
Stress at work | 15.00 | 13.20 | 28 | 392685 | 1123 | 55898231 |
Tooth extraction | 15.00 | 13.20 | 27 | 392686 | 9466 | 55889888 |
Bacterial test positive | 14.93 | 13.20 | 8 | 392705 | 4960 | 55894394 |
Retinal haemorrhage | 14.93 | 13.20 | 7 | 392706 | 4684 | 55894670 |
Drug screen positive | 14.91 | 13.20 | 3 | 392710 | 3461 | 55895893 |
Feeling drunk | 14.90 | 13.20 | 4 | 392709 | 3788 | 55895566 |
Foetal death | 14.89 | 13.20 | 23 | 392690 | 8564 | 55890790 |
Viral upper respiratory tract infection | 14.89 | 13.20 | 94 | 392619 | 7148 | 55892206 |
Eczema | 14.85 | 13.20 | 114 | 392599 | 26039 | 55873315 |
Loss of employment | 14.80 | 13.20 | 38 | 392675 | 1899 | 55897455 |
SARS-CoV-2 test positive | 14.77 | 13.20 | 13 | 392700 | 6216 | 55893138 |
Breast cancer recurrent | 14.74 | 13.20 | 5 | 392708 | 4070 | 55895284 |
Thrombotic microangiopathy | 14.67 | 13.20 | 27 | 392686 | 9384 | 55889970 |
Hepatic cirrhosis | 14.66 | 13.20 | 219 | 392494 | 21044 | 55878310 |
Large intestine polyp | 14.64 | 13.20 | 19 | 392694 | 7608 | 55891746 |
Parotid gland enlargement | 14.64 | 13.20 | 23 | 392690 | 801 | 55898553 |
Aplasia pure red cell | 14.58 | 13.20 | 6 | 392707 | 4336 | 55895018 |
Pleural thickening | 14.57 | 13.20 | 47 | 392666 | 2676 | 55896678 |
Trigeminal neuralgia | 14.56 | 13.20 | 3 | 392710 | 3404 | 55895950 |
Facial paralysis | 14.55 | 13.20 | 46 | 392667 | 13265 | 55886089 |
Abdominal hernia | 14.54 | 13.20 | 7 | 392706 | 4612 | 55894742 |
Pyelonephritis acute | 14.51 | 13.20 | 6 | 392707 | 4323 | 55895031 |
Ammonia increased | 14.51 | 13.20 | 6 | 392707 | 4323 | 55895031 |
Blepharospasm | 14.51 | 13.20 | 3 | 392710 | 3395 | 55895959 |
Arterial occlusive disease | 14.46 | 13.20 | 10 | 392703 | 5400 | 55893954 |
Granuloma | 14.40 | 13.20 | 76 | 392637 | 5411 | 55893943 |
Brain herniation | 14.40 | 13.20 | 3 | 392710 | 3377 | 55895977 |
Road traffic accident | 14.36 | 13.20 | 125 | 392588 | 27802 | 55871552 |
Atypical pneumonia | 14.36 | 13.20 | 5 | 392708 | 4003 | 55895351 |
Gingival swelling | 14.34 | 13.20 | 5 | 392708 | 4001 | 55895353 |
Malignant neoplasm of conjunctiva | 14.34 | 13.20 | 7 | 392706 | 43 | 55899311 |
Venous thrombosis | 14.32 | 13.20 | 7 | 392706 | 4573 | 55894781 |
Facial bones fracture | 14.32 | 13.20 | 3 | 392710 | 3364 | 55895990 |
Tongue oedema | 14.26 | 13.20 | 5 | 392708 | 3987 | 55895367 |
Intervertebral disc compression | 14.23 | 13.20 | 25 | 392688 | 956 | 55898398 |
Pain in extremity | 14.23 | 13.20 | 2322 | 390391 | 295109 | 55604245 |
Pelvic fracture | 14.22 | 13.20 | 41 | 392672 | 12172 | 55887182 |
Escherichia urinary tract infection | 14.17 | 13.20 | 35 | 392678 | 10940 | 55888414 |
Formication | 14.14 | 13.20 | 5 | 392708 | 3965 | 55895389 |
Bunion operation | 14.10 | 13.20 | 28 | 392685 | 1177 | 55898177 |
Skin tightness | 14.05 | 13.20 | 5 | 392708 | 3950 | 55895404 |
Spinal fusion surgery | 14.03 | 13.20 | 65 | 392648 | 4391 | 55894963 |
Aphonia | 13.99 | 13.20 | 26 | 392687 | 9003 | 55890351 |
Breast mass | 13.98 | 13.20 | 17 | 392696 | 7002 | 55892352 |
Catheter site infection | 13.97 | 13.20 | 7 | 392706 | 4507 | 55894847 |
Amnesia | 13.95 | 13.20 | 233 | 392480 | 46089 | 55853265 |
Breast cyst excision | 13.95 | 13.20 | 8 | 392705 | 71 | 55899283 |
Lung consolidation | 13.93 | 13.20 | 5 | 392708 | 3929 | 55895425 |
Neutrophilia | 13.93 | 13.20 | 5 | 392708 | 3928 | 55895426 |
Lupus vulgaris | 13.88 | 13.20 | 37 | 392676 | 1892 | 55897462 |
Stridor | 13.88 | 13.20 | 3 | 392710 | 3292 | 55896062 |
Female genital tract fistula | 13.85 | 13.20 | 7 | 392706 | 4485 | 55894869 |
Bundle branch block right | 13.75 | 13.20 | 8 | 392705 | 4739 | 55894615 |
Renal pain | 13.72 | 13.20 | 13 | 392700 | 6000 | 55893354 |
Coronary artery stenosis | 13.72 | 13.20 | 7 | 392706 | 4461 | 55894893 |
Hyperpyrexia | 13.72 | 13.20 | 3 | 392710 | 3265 | 55896089 |
Galactorrhoea | 13.71 | 13.20 | 5 | 392708 | 3890 | 55895464 |
Hair texture abnormal | 13.69 | 13.20 | 5 | 392708 | 3887 | 55895467 |
Intestinal ischaemia | 13.69 | 13.20 | 17 | 392696 | 6938 | 55892416 |
Hydrocephalus | 13.63 | 13.20 | 9 | 392704 | 4980 | 55894374 |
Tongue disorder | 13.61 | 13.20 | 118 | 392595 | 9918 | 55889436 |
Diverticulum oesophageal | 13.56 | 13.20 | 10 | 392703 | 141 | 55899213 |
Off label use | 13.54 | 13.20 | 4207 | 388506 | 551973 | 55347381 |
Polydipsia | 13.52 | 13.20 | 3 | 392710 | 3232 | 55896122 |
Portal hypertension | 13.42 | 13.20 | 4 | 392709 | 3537 | 55895817 |
Uterine haemorrhage | 13.42 | 13.20 | 4 | 392709 | 3536 | 55895818 |
Hepatic cancer | 13.38 | 13.20 | 6 | 392707 | 4121 | 55895233 |
Blood urine present | 13.35 | 13.20 | 49 | 392664 | 13506 | 55885848 |
Sluggishness | 13.34 | 13.20 | 8 | 392705 | 4660 | 55894694 |
Acute hepatitis C | 13.32 | 13.20 | 8 | 392705 | 78 | 55899276 |
Dysaesthesia | 13.32 | 13.20 | 6 | 392707 | 4110 | 55895244 |
Injection site nodule | 13.29 | 13.20 | 4 | 392709 | 3515 | 55895839 |
Paradoxical drug reaction | 13.28 | 13.20 | 5 | 392708 | 3815 | 55895539 |
Impaired driving ability | 13.21 | 13.20 | 6 | 392707 | 4090 | 55895264 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Rheumatoid arthritis | 2635.75 | 15.02 | 1438 | 58962 | 46371 | 31590573 |
Drug ineffective | 2300.02 | 15.02 | 3246 | 57154 | 392327 | 31244617 |
Joint swelling | 1568.41 | 15.02 | 1075 | 59325 | 52356 | 31584588 |
Drug intolerance | 1508.52 | 15.02 | 1039 | 59361 | 50994 | 31585950 |
Contraindicated product administered | 913.59 | 15.02 | 531 | 59869 | 19241 | 31617703 |
Treatment failure | 760.13 | 15.02 | 626 | 59774 | 40166 | 31596778 |
Synovitis | 692.45 | 15.02 | 376 | 60024 | 11907 | 31625037 |
C-reactive protein abnormal | 679.07 | 15.02 | 320 | 60080 | 7449 | 31629495 |
Apparent death | 595.38 | 15.02 | 233 | 60167 | 3372 | 31633572 |
Arthralgia | 568.65 | 15.02 | 1026 | 59374 | 150398 | 31486546 |
Arthropathy | 537.53 | 15.02 | 411 | 59989 | 23640 | 31613304 |
Musculoskeletal stiffness | 509.99 | 15.02 | 503 | 59897 | 40822 | 31596122 |
Bone erosion | 506.34 | 15.02 | 204 | 60196 | 3199 | 31633745 |
Therapeutic product effect decreased | 492.26 | 15.02 | 438 | 59962 | 31184 | 31605760 |
Pain | 472.49 | 15.02 | 1074 | 59326 | 185685 | 31451259 |
Diverticulitis | 441.74 | 15.02 | 330 | 60070 | 18315 | 31618629 |
Red blood cell sedimentation rate abnormal | 438.74 | 15.02 | 178 | 60222 | 2844 | 31634100 |
Drug hypersensitivity | 407.24 | 15.02 | 591 | 59809 | 72008 | 31564936 |
Psoriatic arthropathy | 363.36 | 15.02 | 302 | 60098 | 19581 | 31617363 |
Drug eruption | 321.47 | 15.02 | 271 | 60129 | 17916 | 31619028 |
Loss of personal independence in daily activities | 318.84 | 15.02 | 328 | 60072 | 27960 | 31608984 |
Urticaria | 297.57 | 15.02 | 451 | 59949 | 57066 | 31579878 |
Mobility decreased | 288.97 | 15.02 | 307 | 60093 | 27162 | 31609782 |
Stomatitis | 271.98 | 15.02 | 355 | 60045 | 39083 | 31597861 |
Pain in extremity | 268.60 | 15.02 | 646 | 59754 | 115557 | 31521387 |
Death | 266.77 | 15.02 | 181 | 60219 | 360388 | 31276556 |
Red blood cell sedimentation rate increased | 265.62 | 15.02 | 177 | 60223 | 8169 | 31628775 |
Hand deformity | 264.60 | 15.02 | 125 | 60275 | 2922 | 31634022 |
C-reactive protein increased | 248.07 | 15.02 | 379 | 60021 | 48271 | 31588673 |
Hypotension | 218.52 | 15.02 | 60 | 60340 | 204558 | 31432386 |
Sleep disorder due to general medical condition, insomnia type | 215.09 | 15.02 | 84 | 60316 | 1207 | 31635737 |
Hypersensitivity | 215.06 | 15.02 | 383 | 60017 | 55360 | 31581584 |
Disability | 214.53 | 15.02 | 125 | 60275 | 4536 | 31632408 |
Arthritis | 208.48 | 15.02 | 259 | 60141 | 27126 | 31609818 |
Febrile neutropenia | 197.66 | 15.02 | 8 | 60392 | 121841 | 31515103 |
Impaired work ability | 190.29 | 15.02 | 126 | 60274 | 5751 | 31631193 |
Acute kidney injury | 189.00 | 15.02 | 154 | 60246 | 279560 | 31357384 |
Therapeutic product effect incomplete | 186.50 | 15.02 | 314 | 60086 | 43382 | 31593562 |
Rheumatoid factor negative | 183.37 | 15.02 | 67 | 60333 | 792 | 31636152 |
Rheumatoid nodule | 176.24 | 15.02 | 91 | 60309 | 2590 | 31634354 |
Alanine aminotransferase abnormal | 173.67 | 15.02 | 103 | 60297 | 3864 | 31633080 |
Anti-cyclic citrullinated peptide antibody positive | 170.29 | 15.02 | 73 | 60327 | 1347 | 31635597 |
Limb discomfort | 169.38 | 15.02 | 147 | 60253 | 10102 | 31626842 |
Peripheral swelling | 168.18 | 15.02 | 388 | 60012 | 67477 | 31569467 |
Knee arthroplasty | 164.04 | 15.02 | 120 | 60280 | 6438 | 31630506 |
Pulmonary thrombosis | 163.27 | 15.02 | 122 | 60278 | 6763 | 31630181 |
Anaemia | 161.77 | 15.02 | 104 | 60296 | 213418 | 31423526 |
Chondropathy | 159.50 | 15.02 | 62 | 60338 | 879 | 31636065 |
Gastrointestinal disorder | 152.17 | 15.02 | 236 | 60164 | 30424 | 31606520 |
Bone cyst | 150.24 | 15.02 | 63 | 60337 | 1098 | 31635846 |
Osteoarthritis | 149.38 | 15.02 | 183 | 60217 | 18884 | 31618060 |
Confusional state | 148.12 | 15.02 | 36 | 60364 | 133298 | 31503646 |
Toxicity to various agents | 147.84 | 15.02 | 81 | 60319 | 181406 | 31455538 |
Tenosynovitis | 145.43 | 15.02 | 94 | 60306 | 4116 | 31632828 |
Enthesopathy | 141.43 | 15.02 | 93 | 60307 | 4194 | 31632750 |
Drug tolerance decreased | 139.05 | 15.02 | 68 | 60332 | 1719 | 31635225 |
Onychoclasis | 138.76 | 15.02 | 68 | 60332 | 1727 | 31635217 |
Lymphoma | 138.12 | 15.02 | 135 | 60265 | 10808 | 31626136 |
Swelling | 138.02 | 15.02 | 252 | 60148 | 37106 | 31599838 |
Terminal state | 136.25 | 15.02 | 86 | 60314 | 3612 | 31633332 |
Drug interaction | 135.54 | 15.02 | 119 | 60281 | 208424 | 31428520 |
Malignant neoplasm progression | 132.20 | 15.02 | 4 | 60396 | 78994 | 31557950 |
Constipation | 127.34 | 15.02 | 39 | 60361 | 123952 | 31512992 |
Atlantoaxial instability | 125.00 | 15.02 | 40 | 60360 | 305 | 31636639 |
Dehydration | 124.99 | 15.02 | 36 | 60364 | 119075 | 31517869 |
Spinal instability | 122.79 | 15.02 | 40 | 60360 | 325 | 31636619 |
Herpes zoster | 122.23 | 15.02 | 219 | 60181 | 31774 | 31605170 |
Mineral metabolism disorder | 122.04 | 15.02 | 40 | 60360 | 332 | 31636612 |
Joint ankylosis | 121.25 | 15.02 | 53 | 60347 | 1027 | 31635917 |
Hepatic function abnormal | 120.56 | 15.02 | 252 | 60148 | 40970 | 31595974 |
Thrombocytopenia | 118.70 | 15.02 | 62 | 60338 | 142685 | 31494259 |
Dislocation of vertebra | 115.81 | 15.02 | 40 | 60360 | 396 | 31636548 |
Sarcoidosis | 114.39 | 15.02 | 69 | 60331 | 2670 | 31634274 |
Acne cystic | 113.41 | 15.02 | 41 | 60359 | 469 | 31636475 |
Overdose | 113.29 | 15.02 | 14 | 60386 | 84650 | 31552294 |
Drug specific antibody present | 111.53 | 15.02 | 69 | 60331 | 2796 | 31634148 |
Inflammation | 111.13 | 15.02 | 184 | 60216 | 25057 | 31611887 |
Dizziness | 107.54 | 15.02 | 133 | 60267 | 199014 | 31437930 |
Intervertebral disc space narrowing | 104.60 | 15.02 | 46 | 60354 | 905 | 31636039 |
Rhabdomyolysis | 103.63 | 15.02 | 4 | 60396 | 63577 | 31573367 |
Tooth loss | 102.24 | 15.02 | 72 | 60328 | 3636 | 31633308 |
Alopecia | 100.85 | 15.02 | 158 | 60242 | 20537 | 31616407 |
Pyrexia | 100.01 | 15.02 | 275 | 60125 | 303565 | 31333379 |
Tongue disorder | 97.44 | 15.02 | 79 | 60321 | 4938 | 31632006 |
Vomiting | 94.52 | 15.02 | 177 | 60223 | 223796 | 31413148 |
Decreased appetite | 92.89 | 15.02 | 93 | 60307 | 153124 | 31483820 |
Joint arthroplasty | 92.13 | 15.02 | 40 | 60360 | 762 | 31636182 |
Seizure | 91.12 | 15.02 | 38 | 60362 | 99730 | 31537214 |
Osteolysis | 90.74 | 15.02 | 56 | 60344 | 2259 | 31634685 |
Bradycardia | 89.08 | 15.02 | 13 | 60387 | 69314 | 31567630 |
Hyperkalaemia | 87.66 | 15.02 | 10 | 60390 | 64341 | 31572603 |
Rheumatoid factor positive | 87.60 | 15.02 | 37 | 60363 | 657 | 31636287 |
Joint stiffness | 86.39 | 15.02 | 101 | 60299 | 9920 | 31627024 |
Neutropenia | 85.30 | 15.02 | 85 | 60315 | 140279 | 31496665 |
Hip arthroplasty | 85.18 | 15.02 | 67 | 60333 | 4008 | 31632936 |
Pulmonary fibrosis | 85.10 | 15.02 | 130 | 60270 | 16530 | 31620414 |
Somnolence | 84.39 | 15.02 | 42 | 60358 | 99403 | 31537541 |
Fall | 82.11 | 15.02 | 143 | 60257 | 185946 | 31450998 |
Epistaxis | 81.26 | 15.02 | 256 | 60144 | 53451 | 31583493 |
Infection | 79.47 | 15.02 | 338 | 60062 | 81593 | 31555351 |
Disease progression | 78.60 | 15.02 | 37 | 60363 | 90427 | 31546517 |
Osteosclerosis | 78.60 | 15.02 | 41 | 60359 | 1192 | 31635752 |
Foot deformity | 77.77 | 15.02 | 64 | 60336 | 4085 | 31632859 |
Agitation | 77.46 | 15.02 | 7 | 60393 | 54162 | 31582782 |
Musculoskeletal discomfort | 76.47 | 15.02 | 80 | 60320 | 6943 | 31630001 |
Plasma cell myeloma | 76.46 | 15.02 | 9 | 60391 | 56522 | 31580422 |
Cardiac arrest | 74.99 | 15.02 | 38 | 60362 | 89024 | 31547920 |
Ill-defined disorder | 74.14 | 15.02 | 105 | 60295 | 12472 | 31624472 |
Tooth fracture | 74.06 | 15.02 | 57 | 60343 | 3302 | 31633642 |
Intestinal sepsis | 73.78 | 15.02 | 31 | 60369 | 543 | 31636401 |
End stage renal disease | 73.71 | 15.02 | 84 | 60316 | 8025 | 31628919 |
Cytology abnormal | 73.67 | 15.02 | 28 | 60372 | 372 | 31636572 |
Liver function test increased | 73.26 | 15.02 | 105 | 60295 | 12609 | 31624335 |
Drug use disorder | 71.67 | 15.02 | 60 | 60340 | 3923 | 31633021 |
Nodule | 71.42 | 15.02 | 70 | 60330 | 5620 | 31631324 |
Gait inability | 70.49 | 15.02 | 129 | 60271 | 19015 | 31617929 |
Muscle spasms | 70.27 | 15.02 | 287 | 60113 | 68031 | 31568913 |
Atrial fibrillation | 67.86 | 15.02 | 70 | 60330 | 113713 | 31523231 |
Photosensitivity reaction | 66.40 | 15.02 | 88 | 60312 | 9816 | 31627128 |
Intentional overdose | 66.11 | 15.02 | 3 | 60397 | 41386 | 31595558 |
Joint range of motion decreased | 65.69 | 15.02 | 72 | 60328 | 6589 | 31630355 |
Tendonitis | 65.17 | 15.02 | 81 | 60319 | 8477 | 31628467 |
International normalised ratio increased | 64.24 | 15.02 | 6 | 60394 | 45217 | 31591727 |
Joint lock | 63.56 | 15.02 | 35 | 60365 | 1137 | 31635807 |
Haemorrhage | 62.87 | 15.02 | 8 | 60392 | 47326 | 31589618 |
Deep vein thrombosis | 62.34 | 15.02 | 255 | 60145 | 60481 | 31576463 |
Platelet count decreased | 61.37 | 15.02 | 72 | 60328 | 110363 | 31526581 |
Hyponatraemia | 61.35 | 15.02 | 32 | 60368 | 73767 | 31563177 |
Seronegative arthritis | 60.92 | 15.02 | 32 | 60368 | 944 | 31636000 |
Hypokalaemia | 60.34 | 15.02 | 14 | 60386 | 53560 | 31583384 |
Cardiac failure congestive | 59.51 | 15.02 | 39 | 60361 | 79348 | 31557596 |
Skin ulcer | 59.35 | 15.02 | 123 | 60277 | 19862 | 31617082 |
Abdominal pain | 59.16 | 15.02 | 118 | 60282 | 145834 | 31491110 |
Suicide attempt | 58.52 | 15.02 | 3 | 60397 | 37245 | 31599699 |
Tachycardia | 57.72 | 15.02 | 37 | 60363 | 76170 | 31560774 |
Syncope | 57.18 | 15.02 | 47 | 60353 | 85135 | 31551809 |
Polyomavirus-associated nephropathy | 56.58 | 15.02 | 50 | 60350 | 3518 | 31633426 |
Ankle deformity | 56.27 | 15.02 | 20 | 60380 | 217 | 31636727 |
Mental status changes | 56.19 | 15.02 | 3 | 60397 | 35965 | 31600979 |
Localised infection | 55.11 | 15.02 | 102 | 60298 | 15163 | 31621781 |
Hallucination | 54.56 | 15.02 | 11 | 60389 | 46399 | 31590545 |
Mass | 52.04 | 15.02 | 67 | 60333 | 7264 | 31629680 |
Pneumonia aspiration | 50.34 | 15.02 | 7 | 60393 | 38719 | 31598225 |
Skin laceration | 50.06 | 15.02 | 83 | 60317 | 11308 | 31625636 |
Dyspnoea | 49.09 | 15.02 | 419 | 59981 | 343060 | 31293884 |
Prerenal failure | 48.82 | 15.02 | 35 | 60365 | 1818 | 31635126 |
Hypoglycaemia | 48.80 | 15.02 | 18 | 60382 | 50928 | 31586016 |
Blood glucose increased | 48.57 | 15.02 | 28 | 60372 | 61055 | 31575889 |
Myalgia | 47.79 | 15.02 | 46 | 60354 | 77212 | 31559732 |
Exposure via body fluid | 47.62 | 15.02 | 15 | 60385 | 108 | 31636836 |
Fine motor skill dysfunction | 47.02 | 15.02 | 33 | 60367 | 1657 | 31635287 |
Neutrophil count decreased | 46.84 | 15.02 | 15 | 60385 | 46379 | 31590565 |
Electrocardiogram QT prolonged | 46.80 | 15.02 | 8 | 60392 | 37979 | 31598965 |
Musculoskeletal pain | 46.77 | 15.02 | 144 | 60256 | 29684 | 31607260 |
Hyperglycaemia | 46.47 | 15.02 | 7 | 60393 | 36469 | 31600475 |
Musculoskeletal disorder | 46.38 | 15.02 | 56 | 60344 | 5688 | 31631256 |
Ankylosing spondylitis | 45.32 | 15.02 | 56 | 60344 | 5825 | 31631119 |
Cardio-respiratory arrest | 45.15 | 15.02 | 21 | 60379 | 51705 | 31585239 |
Oral surgery | 44.88 | 15.02 | 22 | 60378 | 559 | 31636385 |
Therapeutic response decreased | 44.41 | 15.02 | 131 | 60269 | 26378 | 31610566 |
Delirium | 44.36 | 15.02 | 12 | 60388 | 41409 | 31595535 |
Physical disability | 44.12 | 15.02 | 29 | 60371 | 1306 | 31635638 |
Joint effusion | 44.12 | 15.02 | 49 | 60351 | 4550 | 31632394 |
Diabetes mellitus | 43.91 | 15.02 | 179 | 60221 | 42377 | 31594567 |
Urinary tract infection | 43.90 | 15.02 | 49 | 60351 | 76820 | 31560124 |
Soft tissue swelling | 43.66 | 15.02 | 19 | 60381 | 364 | 31636580 |
Tuberculin test positive | 43.55 | 15.02 | 27 | 60373 | 1098 | 31635846 |
Abdominal discomfort | 43.37 | 15.02 | 204 | 60196 | 51363 | 31585581 |
Loss of consciousness | 42.35 | 15.02 | 51 | 60349 | 77304 | 31559640 |
Grip strength decreased | 41.80 | 15.02 | 37 | 60363 | 2609 | 31634335 |
Blood creatine phosphokinase increased | 41.62 | 15.02 | 14 | 60386 | 41960 | 31594984 |
Pulmonary mass | 41.38 | 15.02 | 76 | 60324 | 11230 | 31625714 |
Granuloma | 40.61 | 15.02 | 38 | 60362 | 2879 | 31634065 |
Product dose omission issue | 39.71 | 15.02 | 89 | 60311 | 105497 | 31531447 |
Hospitalisation | 39.35 | 15.02 | 23 | 60377 | 49784 | 31587160 |
Skin mass | 39.04 | 15.02 | 41 | 60359 | 3573 | 31633371 |
Rheumatoid lung | 39.04 | 15.02 | 22 | 60378 | 748 | 31636196 |
Cerebrovascular accident | 38.83 | 15.02 | 57 | 60343 | 79427 | 31557517 |
Interstitial lung disease | 38.57 | 15.02 | 224 | 60176 | 61179 | 31575765 |
Hepatic cirrhosis | 38.07 | 15.02 | 89 | 60311 | 15585 | 31621359 |
Pulmonary embolism | 37.92 | 15.02 | 276 | 60124 | 81370 | 31555574 |
Medical device implantation | 37.77 | 15.02 | 20 | 60380 | 600 | 31636344 |
Immobile | 37.28 | 15.02 | 33 | 60367 | 2327 | 31634617 |
Liver disorder | 37.27 | 15.02 | 133 | 60267 | 29574 | 31607370 |
Respiratory failure | 36.95 | 15.02 | 87 | 60313 | 101362 | 31535582 |
Dysarthria | 36.78 | 15.02 | 8 | 60392 | 32009 | 31604935 |
Lactic acidosis | 36.65 | 15.02 | 8 | 60392 | 31929 | 31605015 |
X-ray abnormal | 36.62 | 15.02 | 18 | 60382 | 460 | 31636484 |
Finger deformity | 36.62 | 15.02 | 25 | 60375 | 1200 | 31635744 |
Abdominal distension | 36.50 | 15.02 | 26 | 60374 | 50658 | 31586286 |
Tooth disorder | 36.18 | 15.02 | 67 | 60333 | 9962 | 31626982 |
Haematuria | 35.73 | 15.02 | 22 | 60378 | 46292 | 31590652 |
Flushing | 35.70 | 15.02 | 7 | 60393 | 30121 | 31606823 |
Urinary retention | 35.68 | 15.02 | 10 | 60390 | 33715 | 31603229 |
Red blood cell sedimentation rate | 35.45 | 15.02 | 23 | 60377 | 1013 | 31635931 |
Intentional product misuse | 35.36 | 15.02 | 14 | 60386 | 37937 | 31599007 |
Dactylitis | 34.59 | 15.02 | 21 | 60379 | 822 | 31636122 |
Hepatic enzyme abnormal | 34.52 | 15.02 | 32 | 60368 | 2396 | 31634548 |
Multiple organ dysfunction syndrome | 34.21 | 15.02 | 48 | 60352 | 68155 | 31568789 |
Granuloma skin | 33.61 | 15.02 | 23 | 60377 | 1108 | 31635836 |
Pyopneumothorax | 33.59 | 15.02 | 10 | 60390 | 58 | 31636886 |
Gastrointestinal haemorrhage | 33.19 | 15.02 | 67 | 60333 | 82482 | 31554462 |
Suicidal ideation | 32.99 | 15.02 | 14 | 60386 | 36392 | 31600552 |
Intentional product use issue | 32.95 | 15.02 | 183 | 60217 | 49164 | 31587780 |
Unresponsive to stimuli | 32.75 | 15.02 | 5 | 60395 | 25795 | 31611149 |
Septic shock | 32.75 | 15.02 | 47 | 60353 | 66111 | 31570833 |
Hypoxia | 32.23 | 15.02 | 29 | 60371 | 50284 | 31586660 |
Limb deformity | 31.74 | 15.02 | 17 | 60383 | 522 | 31636422 |
Metabolic acidosis | 31.66 | 15.02 | 18 | 60382 | 39559 | 31597385 |
Renal impairment | 31.48 | 15.02 | 74 | 60326 | 86275 | 31550669 |
Coronary artery disease | 31.44 | 15.02 | 25 | 60375 | 46062 | 31590882 |
Coma | 31.12 | 15.02 | 20 | 60380 | 41130 | 31595814 |
Blood pressure decreased | 30.47 | 15.02 | 28 | 60372 | 48063 | 31588881 |
Blood parathyroid hormone decreased | 30.39 | 15.02 | 23 | 60377 | 1299 | 31635645 |
Blood creatinine increased | 30.39 | 15.02 | 79 | 60321 | 88999 | 31547945 |
Respiratory distress | 30.25 | 15.02 | 13 | 60387 | 33540 | 31603404 |
Depressed level of consciousness | 30.24 | 15.02 | 18 | 60382 | 38583 | 31598361 |
Pancreatitis acute | 30.22 | 15.02 | 6 | 60394 | 25594 | 31611350 |
Product use in unapproved indication | 30.11 | 15.02 | 93 | 60307 | 99078 | 31537866 |
Polyarthritis | 28.84 | 15.02 | 38 | 60362 | 4214 | 31632730 |
Food intolerance | 28.68 | 15.02 | 22 | 60378 | 1268 | 31635676 |
Intestinal obstruction | 28.57 | 15.02 | 3 | 60397 | 20607 | 31616337 |
Hypocalcaemia | 28.50 | 15.02 | 4 | 60396 | 21974 | 31614970 |
Stent placement | 28.49 | 15.02 | 40 | 60360 | 4711 | 31632233 |
Oral disorder | 28.04 | 15.02 | 36 | 60364 | 3891 | 31633053 |
Oedema | 27.91 | 15.02 | 24 | 60376 | 42537 | 31594407 |
Speech disorder | 27.89 | 15.02 | 6 | 60394 | 24195 | 31612749 |
Asthenia | 27.78 | 15.02 | 284 | 60116 | 224471 | 31412473 |
Lymphoedema | 27.75 | 15.02 | 34 | 60366 | 3506 | 31633438 |
Dysphagia | 27.54 | 15.02 | 42 | 60358 | 57634 | 31579310 |
Respiratory arrest | 27.38 | 15.02 | 8 | 60392 | 26249 | 31610695 |
Lacrimal disorder | 27.27 | 15.02 | 13 | 60387 | 310 | 31636634 |
Human polyomavirus infection | 27.23 | 15.02 | 17 | 60383 | 700 | 31636244 |
COVID-19 | 27.07 | 15.02 | 39 | 60361 | 54782 | 31582162 |
Fatigue | 27.02 | 15.02 | 463 | 59937 | 334743 | 31302201 |
Fibromyalgia | 26.92 | 15.02 | 30 | 60370 | 2796 | 31634148 |
Chest pain | 26.84 | 15.02 | 123 | 60277 | 116834 | 31520110 |
Exostosis | 26.77 | 15.02 | 35 | 60365 | 3851 | 31633093 |
Toxic epidermal necrolysis | 26.66 | 15.02 | 3 | 60397 | 19521 | 31617423 |
Hepatic enzyme increased | 26.58 | 15.02 | 137 | 60263 | 35771 | 31601173 |
Neoplasm malignant | 26.57 | 15.02 | 88 | 60312 | 18843 | 31618101 |
Cardiac failure | 26.52 | 15.02 | 80 | 60320 | 85873 | 31551071 |
Condition aggravated | 26.37 | 15.02 | 449 | 59951 | 163560 | 31473384 |
Blood cholesterol abnormal | 26.22 | 15.02 | 23 | 60377 | 1602 | 31635342 |
Panniculitis | 26.17 | 15.02 | 24 | 60376 | 1772 | 31635172 |
Disorientation | 26.03 | 15.02 | 13 | 60387 | 30731 | 31606213 |
Hepatic steatosis | 26.01 | 15.02 | 79 | 60321 | 16160 | 31620784 |
Wrist deformity | 25.76 | 15.02 | 13 | 60387 | 352 | 31636592 |
Irritability | 25.73 | 15.02 | 6 | 60394 | 22883 | 31614061 |
Subdural haematoma | 25.69 | 15.02 | 3 | 60397 | 18968 | 31617976 |
Foetal exposure during pregnancy | 25.66 | 15.02 | 24 | 60376 | 40852 | 31596092 |
Cytomegalovirus viraemia | 25.61 | 15.02 | 46 | 60354 | 6679 | 31630265 |
Wrong technique in product usage process | 25.49 | 15.02 | 16 | 60384 | 33327 | 31603617 |
Shoulder operation | 25.19 | 15.02 | 18 | 60382 | 930 | 31636014 |
Chills | 25.10 | 15.02 | 66 | 60334 | 74084 | 31562860 |
Generalised tonic-clonic seizure | 24.99 | 15.02 | 4 | 60396 | 19927 | 31617017 |
Neck pain | 24.93 | 15.02 | 98 | 60302 | 22812 | 31614132 |
Dysgeusia | 24.75 | 15.02 | 7 | 60393 | 23459 | 31613485 |
Pulmonary toxicity | 24.73 | 15.02 | 40 | 60360 | 5337 | 31631607 |
Restlessness | 24.58 | 15.02 | 7 | 60393 | 23354 | 31613590 |
Renal failure | 24.53 | 15.02 | 350 | 60050 | 122980 | 31513964 |
Thrombosis | 24.12 | 15.02 | 158 | 60242 | 44993 | 31591951 |
Haematoma | 24.02 | 15.02 | 8 | 60392 | 24131 | 31612813 |
Aortic bruit | 23.86 | 15.02 | 10 | 60390 | 174 | 31636770 |
Bursitis | 23.85 | 15.02 | 38 | 60362 | 5007 | 31631937 |
Surgery | 23.76 | 15.02 | 65 | 60335 | 12534 | 31624410 |
Heart block congenital | 23.75 | 15.02 | 7 | 60393 | 39 | 31636905 |
Vasculitic rash | 23.71 | 15.02 | 17 | 60383 | 883 | 31636061 |
Splenic embolism | 23.50 | 15.02 | 10 | 60390 | 181 | 31636763 |
Diarrhoea | 23.42 | 15.02 | 503 | 59897 | 351906 | 31285038 |
Cerebral haemorrhage | 23.40 | 15.02 | 17 | 60383 | 32795 | 31604149 |
Elbow operation | 23.38 | 15.02 | 9 | 60391 | 124 | 31636820 |
White blood cell count increased | 23.21 | 15.02 | 24 | 60376 | 38976 | 31597968 |
Cutaneous symptom | 22.78 | 15.02 | 11 | 60389 | 270 | 31636674 |
Epilepsy | 22.71 | 15.02 | 6 | 60394 | 21035 | 31615909 |
Injury | 22.48 | 15.02 | 5 | 60395 | 19704 | 31617240 |
Alanine aminotransferase increased | 22.34 | 15.02 | 229 | 60171 | 74427 | 31562517 |
Accidental overdose | 22.30 | 15.02 | 4 | 60396 | 18346 | 31618598 |
Orthostatic hypotension | 22.30 | 15.02 | 9 | 60391 | 24110 | 31612834 |
Pulmonary cavitation | 22.18 | 15.02 | 16 | 60384 | 839 | 31636105 |
Tooth extraction | 22.14 | 15.02 | 34 | 60366 | 4341 | 31632603 |
Acute respiratory failure | 22.09 | 15.02 | 13 | 60387 | 28042 | 31608902 |
Melaena | 21.91 | 15.02 | 18 | 60382 | 32636 | 31604308 |
Ventricular tachycardia | 21.66 | 15.02 | 9 | 60391 | 23692 | 31613252 |
Unevaluable event | 21.60 | 15.02 | 16 | 60384 | 30559 | 31606385 |
Sideroblastic anaemia | 21.59 | 15.02 | 10 | 60390 | 223 | 31636721 |
Full blood count decreased | 21.47 | 15.02 | 3 | 60397 | 16537 | 31620407 |
Blood pressure fluctuation | 21.39 | 15.02 | 93 | 60307 | 22643 | 31614301 |
Gastric disorder | 21.27 | 15.02 | 59 | 60341 | 11469 | 31625475 |
Arrhythmia | 21.26 | 15.02 | 19 | 60381 | 33058 | 31603886 |
Impaired healing | 21.01 | 15.02 | 67 | 60333 | 14065 | 31622879 |
Therapy non-responder | 20.99 | 15.02 | 123 | 60277 | 33688 | 31603256 |
Histoplasmosis | 20.87 | 15.02 | 19 | 60381 | 1390 | 31635554 |
Cytomegalovirus syndrome | 20.87 | 15.02 | 8 | 60392 | 109 | 31636835 |
Soft tissue inflammation | 20.66 | 15.02 | 7 | 60393 | 65 | 31636879 |
Ossicle disorder | 20.58 | 15.02 | 6 | 60394 | 32 | 31636912 |
C-reactive protein decreased | 20.34 | 15.02 | 21 | 60379 | 1794 | 31635150 |
Hypertension | 20.32 | 15.02 | 350 | 60050 | 127750 | 31509194 |
Arthrodesis | 20.28 | 15.02 | 12 | 60388 | 448 | 31636496 |
Steatorrhoea | 20.18 | 15.02 | 14 | 60386 | 690 | 31636254 |
Rash maculo-papular | 20.14 | 15.02 | 12 | 60388 | 25707 | 31611237 |
Hypervolaemia | 20.09 | 15.02 | 5 | 60395 | 18246 | 31618698 |
Spina bifida occulta | 19.95 | 15.02 | 5 | 60395 | 13 | 31636931 |
Diaphragmatic injury | 19.70 | 15.02 | 8 | 60392 | 128 | 31636816 |
Drug reaction with eosinophilia and systemic symptoms | 19.59 | 15.02 | 17 | 60383 | 30001 | 31606943 |
Arthritis bacterial | 19.57 | 15.02 | 33 | 60367 | 4557 | 31632387 |
Lethargy | 19.56 | 15.02 | 27 | 60373 | 38614 | 31598330 |
Head injury | 19.46 | 15.02 | 4 | 60396 | 16654 | 31620290 |
Cell-mediated cytotoxicity | 19.45 | 15.02 | 6 | 60394 | 40 | 31636904 |
Retinal scar | 19.45 | 15.02 | 10 | 60390 | 282 | 31636662 |
Diffuse idiopathic skeletal hyperostosis | 19.45 | 15.02 | 6 | 60394 | 40 | 31636904 |
Dermatitis psoriasiform | 19.39 | 15.02 | 17 | 60383 | 1183 | 31635761 |
Hepatotoxicity | 19.36 | 15.02 | 80 | 60320 | 19046 | 31617898 |
Vitamin B1 decreased | 19.35 | 15.02 | 10 | 60390 | 285 | 31636659 |
Latent tuberculosis | 19.10 | 15.02 | 17 | 60383 | 1207 | 31635737 |
Fracture | 19.05 | 15.02 | 39 | 60361 | 6241 | 31630703 |
Full blood count abnormal | 18.95 | 15.02 | 4 | 60396 | 16343 | 31620601 |
Fear of injection | 18.78 | 15.02 | 17 | 60383 | 1234 | 31635710 |
Cartilage injury | 18.77 | 15.02 | 12 | 60388 | 515 | 31636429 |
Chronic kidney disease | 18.76 | 15.02 | 27 | 60373 | 37948 | 31598996 |
Ejection fraction decreased | 18.76 | 15.02 | 5 | 60395 | 17429 | 31619515 |
Vision blurred | 18.62 | 15.02 | 32 | 60368 | 41883 | 31595061 |
Lymphocyte count decreased | 18.61 | 15.02 | 8 | 60392 | 20641 | 31616303 |
Ascites | 18.51 | 15.02 | 31 | 60369 | 40982 | 31595962 |
Joint injury | 18.47 | 15.02 | 44 | 60356 | 7797 | 31629147 |
Cardiac granuloma | 18.30 | 15.02 | 4 | 60396 | 4 | 31636940 |
Paternal drugs affecting foetus | 18.08 | 15.02 | 6 | 60394 | 52 | 31636892 |
Erectile dysfunction | 18.07 | 15.02 | 7 | 60393 | 19228 | 31617716 |
Memory impairment | 17.98 | 15.02 | 28 | 60372 | 38102 | 31598842 |
Oral pustule | 17.89 | 15.02 | 9 | 60391 | 242 | 31636702 |
Psoriasis | 17.84 | 15.02 | 151 | 60249 | 46568 | 31590376 |
Altered state of consciousness | 17.67 | 15.02 | 9 | 60391 | 21042 | 31615902 |
Motor dysfunction | 17.64 | 15.02 | 38 | 60362 | 6301 | 31630643 |
Nail pitting | 17.63 | 15.02 | 9 | 60391 | 250 | 31636694 |
Erythema elevatum diutinum | 17.58 | 15.02 | 5 | 60395 | 24 | 31636920 |
Erythema | 17.52 | 15.02 | 232 | 60168 | 80173 | 31556771 |
Shoulder arthroplasty | 17.51 | 15.02 | 11 | 60389 | 458 | 31636486 |
Fluid retention | 17.49 | 15.02 | 13 | 60387 | 24789 | 31612155 |
Pulmonary granuloma | 17.40 | 15.02 | 17 | 60383 | 1359 | 31635585 |
Anaphylactic shock | 17.37 | 15.02 | 3 | 60397 | 14142 | 31622802 |
Otospondylomegaepiphyseal dysplasia | 17.35 | 15.02 | 7 | 60393 | 110 | 31636834 |
Blood bilirubin increased | 17.34 | 15.02 | 25 | 60375 | 35111 | 31601833 |
Haematocrit decreased | 17.33 | 15.02 | 19 | 60381 | 30042 | 31606902 |
Drug withdrawal syndrome | 17.33 | 15.02 | 7 | 60393 | 18743 | 31618201 |
Medication error | 17.31 | 15.02 | 11 | 60389 | 22761 | 31614183 |
Hernia pain | 17.18 | 15.02 | 9 | 60391 | 264 | 31636680 |
Dental caries | 17.13 | 15.02 | 30 | 60370 | 4271 | 31632673 |
Product administration error | 17.13 | 15.02 | 4 | 60396 | 15243 | 31621701 |
Ileus | 17.00 | 15.02 | 4 | 60396 | 15165 | 31621779 |
Dysphonia | 16.99 | 15.02 | 9 | 60391 | 20582 | 31616362 |
Carditis | 16.97 | 15.02 | 8 | 60392 | 186 | 31636758 |
C-reactive protein | 16.90 | 15.02 | 7 | 60393 | 118 | 31636826 |
Disturbance in attention | 16.85 | 15.02 | 11 | 60389 | 22439 | 31614505 |
Emphysema | 16.81 | 15.02 | 46 | 60354 | 8872 | 31628072 |
Enzyme abnormality | 16.66 | 15.02 | 8 | 60392 | 194 | 31636750 |
Exposure via father | 16.64 | 15.02 | 7 | 60393 | 123 | 31636821 |
Cerebral infarction | 16.60 | 15.02 | 15 | 60385 | 25962 | 31610982 |
Gastritis | 16.55 | 15.02 | 9 | 60391 | 20283 | 31616661 |
Lupus-like syndrome | 16.46 | 15.02 | 22 | 60378 | 2473 | 31634471 |
Stress ulcer | 16.41 | 15.02 | 6 | 60394 | 71 | 31636873 |
Renal tubular necrosis | 16.33 | 15.02 | 4 | 60396 | 14755 | 31622189 |
Hypophagia | 16.27 | 15.02 | 11 | 60389 | 22031 | 31614913 |
Undifferentiated connective tissue disease | 16.25 | 15.02 | 5 | 60395 | 33 | 31636911 |
Sensitivity to weather change | 16.16 | 15.02 | 17 | 60383 | 1484 | 31635460 |
Diabetic ketoacidosis | 16.14 | 15.02 | 6 | 60394 | 16899 | 31620045 |
Encephalopathy | 16.13 | 15.02 | 23 | 60377 | 32451 | 31604493 |
Central nervous system infection | 15.91 | 15.02 | 11 | 60389 | 539 | 31636405 |
Sudden death | 15.83 | 15.02 | 4 | 60396 | 14453 | 31622491 |
Shock | 15.80 | 15.02 | 12 | 60388 | 22633 | 31614311 |
Haemoptysis | 15.79 | 15.02 | 23 | 60377 | 32166 | 31604778 |
Tuberculosis | 15.70 | 15.02 | 43 | 60357 | 8298 | 31628646 |
Blood potassium increased | 15.42 | 15.02 | 5 | 60395 | 15340 | 31621604 |
Hepatic fibrosis | 15.40 | 15.02 | 27 | 60373 | 3847 | 31633097 |
Granulomatous dermatitis | 15.29 | 15.02 | 8 | 60392 | 234 | 31636710 |
Feeding disorder | 15.22 | 15.02 | 36 | 60364 | 6350 | 31630594 |
Dyspnoea exertional | 15.19 | 15.02 | 32 | 60368 | 38805 | 31598139 |
Single functional kidney | 15.19 | 15.02 | 6 | 60394 | 89 | 31636855 |
Urinary incontinence | 15.15 | 15.02 | 7 | 60393 | 17313 | 31619631 |
Myoclonus | 15.08 | 15.02 | 4 | 60396 | 13986 | 31622958 |
Aphthous ulcer | 15.03 | 15.02 | 29 | 60371 | 4445 | 31632499 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Rheumatoid arthritis | 8348.98 | 13.60 | 8311 | 313847 | 283494 | 70322792 |
Drug ineffective | 6318.98 | 13.60 | 13390 | 308768 | 926362 | 69679924 |
Drug intolerance | 5389.78 | 13.60 | 5844 | 316314 | 219843 | 70386443 |
Joint swelling | 4405.61 | 13.60 | 5575 | 316583 | 247636 | 70358650 |
Contraindicated product administered | 3727.65 | 13.60 | 3777 | 318381 | 130835 | 70475451 |
Synovitis | 3534.23 | 13.60 | 3602 | 318556 | 125626 | 70480660 |
Treatment failure | 3048.04 | 13.60 | 3508 | 318650 | 140634 | 70465652 |
Arthropathy | 2643.42 | 13.60 | 3329 | 318829 | 146728 | 70459558 |
Therapeutic product effect decreased | 2373.90 | 13.60 | 3081 | 319077 | 139937 | 70466349 |
Arthralgia | 1717.31 | 13.60 | 5597 | 316561 | 497793 | 70108493 |
Hand deformity | 1652.01 | 13.60 | 2000 | 320158 | 84482 | 70521804 |
Swelling | 1622.07 | 13.60 | 2998 | 319160 | 185541 | 70420745 |
Pain | 1548.22 | 13.60 | 6287 | 315871 | 622529 | 69983757 |
Pemphigus | 1423.40 | 13.60 | 1819 | 320339 | 81217 | 70525069 |
Abdominal discomfort | 1412.46 | 13.60 | 3052 | 319106 | 211606 | 70394680 |
Death | 1373.44 | 13.60 | 318 | 321840 | 509743 | 70096543 |
C-reactive protein abnormal | 1373.22 | 13.60 | 1245 | 320913 | 37334 | 70568952 |
Anti-cyclic citrullinated peptide antibody positive | 1351.34 | 13.60 | 1630 | 320528 | 68555 | 70537731 |
Systemic lupus erythematosus | 1323.67 | 13.60 | 1952 | 320206 | 99950 | 70506336 |
Alopecia | 1313.50 | 13.60 | 2829 | 319329 | 195661 | 70410625 |
Musculoskeletal stiffness | 1278.12 | 13.60 | 2356 | 319802 | 145404 | 70460882 |
Drug hypersensitivity | 1271.45 | 13.60 | 3312 | 318846 | 259147 | 70347139 |
Acute kidney injury | 1259.64 | 13.60 | 305 | 321853 | 474319 | 70131967 |
Rheumatoid factor positive | 1228.51 | 13.60 | 1298 | 320860 | 47102 | 70559184 |
Peripheral swelling | 1212.66 | 13.60 | 3050 | 319108 | 233513 | 70372773 |
Hepatic enzyme increased | 1209.64 | 13.60 | 2383 | 319775 | 154607 | 70451679 |
Glossodynia | 1202.21 | 13.60 | 1711 | 320447 | 84776 | 70521510 |
Hypersensitivity | 1151.80 | 13.60 | 2938 | 319220 | 226874 | 70379412 |
Hypotension | 1011.44 | 13.60 | 292 | 321866 | 404089 | 70202197 |
Red blood cell sedimentation rate abnormal | 991.42 | 13.60 | 770 | 321388 | 18533 | 70587753 |
Pericarditis | 986.95 | 13.60 | 1543 | 320615 | 83162 | 70523124 |
Therapeutic product effect incomplete | 978.29 | 13.60 | 1865 | 320293 | 118017 | 70488269 |
Completed suicide | 938.35 | 13.60 | 19 | 322139 | 227116 | 70379170 |
Toxicity to various agents | 924.81 | 13.60 | 293 | 321865 | 381879 | 70224407 |
Wound | 851.46 | 13.60 | 1573 | 320585 | 97159 | 70509127 |
Loss of personal independence in daily activities | 839.22 | 13.60 | 1436 | 320722 | 83474 | 70522812 |
Drug interaction | 825.70 | 13.60 | 350 | 321808 | 381091 | 70225195 |
Psoriatic arthropathy | 786.71 | 13.60 | 1203 | 320955 | 63568 | 70542718 |
Febrile neutropenia | 786.16 | 13.60 | 33 | 322125 | 204285 | 70402001 |
Anaemia | 769.11 | 13.60 | 439 | 321719 | 402984 | 70203302 |
Red blood cell sedimentation rate increased | 759.03 | 13.60 | 907 | 321251 | 37735 | 70568551 |
Helicobacter infection | 721.91 | 13.60 | 1066 | 321092 | 54590 | 70551696 |
Rash | 714.98 | 13.60 | 4355 | 317803 | 506207 | 70100079 |
Bone erosion | 709.92 | 13.60 | 573 | 321585 | 14600 | 70591686 |
Infection | 702.66 | 13.60 | 2330 | 319828 | 208455 | 70397831 |
Discomfort | 698.87 | 13.60 | 1505 | 320653 | 103931 | 70502355 |
Gastrointestinal disorder | 674.99 | 13.60 | 1484 | 320674 | 103943 | 70502343 |
Duodenal ulcer perforation | 670.16 | 13.60 | 984 | 321174 | 50128 | 70556158 |
Infusion related reaction | 653.39 | 13.60 | 2178 | 319980 | 195356 | 70410930 |
Constipation | 645.98 | 13.60 | 174 | 321984 | 252264 | 70354022 |
Sleep disorder due to general medical condition, insomnia type | 620.01 | 13.60 | 788 | 321370 | 34944 | 70571342 |
Impaired healing | 612.42 | 13.60 | 1162 | 320996 | 73212 | 70533074 |
C-reactive protein increased | 605.39 | 13.60 | 1463 | 320695 | 109054 | 70497232 |
Irritable bowel syndrome | 592.97 | 13.60 | 927 | 321231 | 49923 | 70556363 |
Muscle injury | 585.96 | 13.60 | 796 | 321362 | 37698 | 70568588 |
Folliculitis | 573.22 | 13.60 | 830 | 321328 | 41740 | 70564546 |
Mobility decreased | 564.67 | 13.60 | 1364 | 320794 | 101635 | 70504651 |
Dehydration | 561.58 | 13.60 | 165 | 321993 | 225977 | 70380309 |
Lower respiratory tract infection | 544.28 | 13.60 | 1416 | 320742 | 110497 | 70495789 |
Malignant neoplasm progression | 529.69 | 13.60 | 4 | 322154 | 121735 | 70484551 |
Osteoarthritis | 509.17 | 13.60 | 1074 | 321084 | 73073 | 70533213 |
Overdose | 505.96 | 13.60 | 82 | 322076 | 169663 | 70436623 |
Cardiac arrest | 504.80 | 13.60 | 65 | 322093 | 159769 | 70446517 |
Hyponatraemia | 491.61 | 13.60 | 71 | 322087 | 160016 | 70446270 |
Thrombocytopenia | 483.33 | 13.60 | 241 | 321917 | 238869 | 70367417 |
Arthritis | 481.82 | 13.60 | 1245 | 320913 | 96735 | 70509551 |
Seizure | 481.68 | 13.60 | 109 | 322049 | 177853 | 70428433 |
Rheumatoid nodule | 477.52 | 13.60 | 456 | 321702 | 14611 | 70591675 |
Bradycardia | 473.02 | 13.60 | 22 | 322136 | 124593 | 70481693 |
Condition aggravated | 460.05 | 13.60 | 3419 | 318739 | 424216 | 70182070 |
Ill-defined disorder | 455.19 | 13.60 | 859 | 321299 | 53882 | 70552404 |
Sinusitis | 442.93 | 13.60 | 1729 | 320429 | 167466 | 70438820 |
Somnolence | 425.73 | 13.60 | 224 | 321934 | 215382 | 70390904 |
Neutropenia | 423.26 | 13.60 | 329 | 321829 | 256827 | 70349459 |
Stomatitis | 421.87 | 13.60 | 1414 | 320744 | 127097 | 70479189 |
Intentional overdose | 403.24 | 13.60 | 9 | 322149 | 98426 | 70507860 |
Inflammation | 401.66 | 13.60 | 1014 | 321144 | 77651 | 70528635 |
Hyperkalaemia | 397.58 | 13.60 | 21 | 322137 | 106570 | 70499716 |
Disability | 394.54 | 13.60 | 410 | 321748 | 14573 | 70591713 |
Blister | 393.05 | 13.60 | 1175 | 320983 | 99351 | 70506935 |
Disease progression | 389.39 | 13.60 | 114 | 322044 | 156558 | 70449728 |
Knee arthroplasty | 388.32 | 13.60 | 617 | 321541 | 33684 | 70572602 |
Tremor | 387.22 | 13.60 | 113 | 322045 | 155511 | 70450775 |
Maternal exposure during pregnancy | 381.98 | 13.60 | 1273 | 320885 | 114072 | 70492214 |
Product use issue | 367.26 | 13.60 | 1705 | 320453 | 178232 | 70428054 |
Atrial fibrillation | 363.20 | 13.60 | 192 | 321966 | 184156 | 70422130 |
Foot deformity | 349.58 | 13.60 | 450 | 321708 | 20205 | 70586081 |
Dyspnoea | 345.56 | 13.60 | 2069 | 320089 | 767991 | 69838295 |
Fall | 340.12 | 13.60 | 968 | 321190 | 443128 | 70163158 |
Fibromyalgia | 328.04 | 13.60 | 693 | 321465 | 47181 | 70559105 |
Dizziness | 328.02 | 13.60 | 1050 | 321108 | 463091 | 70143195 |
Tenosynovitis | 326.62 | 13.60 | 359 | 321799 | 13617 | 70592669 |
Hypokalaemia | 319.55 | 13.60 | 99 | 322059 | 131089 | 70475197 |
Drug tolerance decreased | 318.07 | 13.60 | 301 | 321857 | 9532 | 70596754 |
Electrocardiogram QT prolonged | 312.89 | 13.60 | 16 | 322142 | 83501 | 70522785 |
Osteoporosis | 312.26 | 13.60 | 688 | 321470 | 48219 | 70558067 |
Hip arthroplasty | 310.01 | 13.60 | 499 | 321659 | 27541 | 70578745 |
Musculoskeletal disorder | 309.98 | 13.60 | 417 | 321741 | 19554 | 70586732 |
Rhabdomyolysis | 307.01 | 13.60 | 37 | 322121 | 95723 | 70510563 |
Cardio-respiratory arrest | 305.89 | 13.60 | 46 | 322112 | 100631 | 70505655 |
Joint range of motion decreased | 305.45 | 13.60 | 476 | 321682 | 25550 | 70580736 |
Respiratory failure | 299.57 | 13.60 | 199 | 321959 | 168536 | 70437750 |
Tachycardia | 296.61 | 13.60 | 176 | 321982 | 158370 | 70447916 |
Platelet count decreased | 291.86 | 13.60 | 229 | 321929 | 177993 | 70428293 |
Depressed level of consciousness | 289.83 | 13.60 | 30 | 322128 | 87401 | 70518885 |
Drug eruption | 287.33 | 13.60 | 586 | 321572 | 38910 | 70567376 |
Sepsis | 281.07 | 13.60 | 422 | 321736 | 244123 | 70362163 |
Cardiac failure congestive | 278.90 | 13.60 | 133 | 322025 | 135324 | 70470962 |
Hypoglycaemia | 275.74 | 13.60 | 48 | 322110 | 94316 | 70511970 |
Suicide attempt | 274.98 | 13.60 | 23 | 322135 | 79487 | 70526799 |
Granuloma skin | 269.42 | 13.60 | 246 | 321912 | 7436 | 70598850 |
Plasma cell myeloma | 268.09 | 13.60 | 16 | 322142 | 73185 | 70533101 |
Blood parathyroid hormone decreased | 266.95 | 13.60 | 263 | 321895 | 8761 | 70597525 |
Cardiac failure | 263.38 | 13.60 | 163 | 321995 | 143378 | 70462908 |
Agitation | 263.19 | 13.60 | 52 | 322106 | 93323 | 70512963 |
Joint stiffness | 260.74 | 13.60 | 526 | 321632 | 34650 | 70571636 |
Blood cholesterol increased | 258.00 | 13.60 | 761 | 321397 | 63843 | 70542443 |
Cerebrovascular accident | 256.28 | 13.60 | 168 | 321990 | 143302 | 70462984 |
Gastrointestinal haemorrhage | 253.55 | 13.60 | 155 | 322003 | 137253 | 70469033 |
Therapeutic response decreased | 252.24 | 13.60 | 708 | 321450 | 57745 | 70548541 |
Adverse event | 245.58 | 13.60 | 631 | 321527 | 48830 | 70557456 |
Neutrophil count decreased | 245.24 | 13.60 | 42 | 322116 | 83514 | 70522772 |
Panniculitis | 243.89 | 13.60 | 271 | 321887 | 10405 | 70595881 |
Pneumonia aspiration | 243.00 | 13.60 | 9 | 322149 | 62280 | 70544006 |
Nasopharyngitis | 238.44 | 13.60 | 1777 | 320381 | 220429 | 70385857 |
Metabolic acidosis | 237.64 | 13.60 | 29 | 322129 | 74317 | 70531969 |
Syncope | 237.61 | 13.60 | 241 | 321917 | 165468 | 70440818 |
Pyrexia | 233.78 | 13.60 | 1706 | 320452 | 605246 | 70001040 |
Hallucination | 233.61 | 13.60 | 34 | 322124 | 76226 | 70530060 |
Lactic acidosis | 232.81 | 13.60 | 16 | 322142 | 65008 | 70541278 |
International normalised ratio increased | 231.66 | 13.60 | 43 | 322115 | 80683 | 70525603 |
Hypoxia | 229.89 | 13.60 | 69 | 322089 | 93275 | 70513011 |
Abdominal pain | 227.70 | 13.60 | 794 | 321364 | 341333 | 70264953 |
Mental status changes | 224.55 | 13.60 | 16 | 322142 | 63085 | 70543201 |
Product dose omission issue | 218.65 | 13.60 | 409 | 321749 | 217059 | 70389227 |
Pain in extremity | 216.88 | 13.60 | 2361 | 319797 | 325721 | 70280565 |
Rheumatic fever | 214.24 | 13.60 | 328 | 321830 | 17332 | 70588954 |
Anxiety | 214.01 | 13.60 | 423 | 321735 | 219907 | 70386379 |
Vision blurred | 210.16 | 13.60 | 84 | 322074 | 94900 | 70511386 |
Hyperglycaemia | 209.74 | 13.60 | 24 | 322134 | 64648 | 70541638 |
Respiratory arrest | 206.32 | 13.60 | 9 | 322149 | 53924 | 70552362 |
Decreased appetite | 203.65 | 13.60 | 706 | 321452 | 304074 | 70302212 |
Vomiting | 203.23 | 13.60 | 1721 | 320437 | 591390 | 70014896 |
Chest pain | 201.49 | 13.60 | 535 | 321623 | 250725 | 70355561 |
Adverse drug reaction | 201.31 | 13.60 | 616 | 321542 | 52728 | 70553558 |
Unresponsive to stimuli | 200.88 | 13.60 | 8 | 322150 | 51923 | 70554363 |
Urinary tract infection | 197.74 | 13.60 | 532 | 321626 | 248237 | 70358049 |
Swollen joint count increased | 197.44 | 13.60 | 276 | 321882 | 13424 | 70592862 |
Coma | 197.11 | 13.60 | 85 | 322073 | 91759 | 70514527 |
Sedation | 196.54 | 13.60 | 3 | 322155 | 46728 | 70559558 |
Oedema peripheral | 195.80 | 13.60 | 469 | 321689 | 227622 | 70378664 |
Multiple organ dysfunction syndrome | 195.23 | 13.60 | 126 | 322032 | 108389 | 70497897 |
Nodule | 193.50 | 13.60 | 335 | 321823 | 19634 | 70586652 |
Neoplasm progression | 189.81 | 13.60 | 3 | 322155 | 45225 | 70561061 |
Rheumatoid lung | 188.55 | 13.60 | 143 | 322015 | 3316 | 70602970 |
Finger deformity | 187.42 | 13.60 | 182 | 321976 | 5954 | 70600332 |
Enthesopathy | 187.37 | 13.60 | 239 | 321919 | 10630 | 70595656 |
Chest discomfort | 182.75 | 13.60 | 177 | 321981 | 124204 | 70482082 |
Blood glucose increased | 180.63 | 13.60 | 123 | 322035 | 102859 | 70503427 |
Grip strength decreased | 177.30 | 13.60 | 282 | 321876 | 15403 | 70590883 |
Musculoskeletal pain | 173.93 | 13.60 | 842 | 321316 | 89485 | 70516801 |
Aggression | 173.20 | 13.60 | 12 | 322146 | 48434 | 70557852 |
Pulmonary fibrosis | 172.67 | 13.60 | 440 | 321718 | 33870 | 70572416 |
Serotonin syndrome | 171.87 | 13.60 | 4 | 322154 | 42110 | 70564176 |
Balance disorder | 171.41 | 13.60 | 98 | 322060 | 90030 | 70516256 |
Loss of consciousness | 169.96 | 13.60 | 278 | 321880 | 155438 | 70450848 |
Cognitive disorder | 169.57 | 13.60 | 35 | 322123 | 60921 | 70545365 |
Pulmonary embolism | 168.51 | 13.60 | 280 | 321878 | 155587 | 70450699 |
Impaired work ability | 167.40 | 13.60 | 281 | 321877 | 16059 | 70590227 |
Dysarthria | 166.82 | 13.60 | 39 | 322119 | 62274 | 70544012 |
Urinary retention | 164.18 | 13.60 | 22 | 322136 | 52498 | 70553788 |
Asthenia | 162.47 | 13.60 | 1315 | 320843 | 456351 | 70149935 |
Apparent death | 161.92 | 13.60 | 120 | 322038 | 2684 | 70603602 |
COVID-19 | 160.65 | 13.60 | 146 | 322012 | 105611 | 70500675 |
Renal failure | 160.47 | 13.60 | 391 | 321767 | 188679 | 70417607 |
Blood pressure decreased | 159.57 | 13.60 | 110 | 322048 | 91405 | 70514881 |
Blood creatine phosphokinase increased | 158.83 | 13.60 | 41 | 322117 | 61222 | 70545064 |
Cerebral haemorrhage | 158.22 | 13.60 | 27 | 322131 | 53837 | 70552449 |
Skin ulcer | 158.03 | 13.60 | 530 | 321628 | 47615 | 70558671 |
Respiratory distress | 157.03 | 13.60 | 29 | 322129 | 54621 | 70551665 |
Rheumatoid factor negative | 156.50 | 13.60 | 84 | 322074 | 1038 | 70605248 |
White blood cell count decreased | 156.40 | 13.60 | 337 | 321821 | 169804 | 70436482 |
Orthostatic hypotension | 156.33 | 13.60 | 24 | 322134 | 51719 | 70554567 |
Lethargy | 156.21 | 13.60 | 73 | 322085 | 75177 | 70531109 |
Septic shock | 155.54 | 13.60 | 168 | 321990 | 112090 | 70494196 |
Intentional product misuse | 155.04 | 13.60 | 84 | 322074 | 79511 | 70526775 |
Encephalopathy | 154.72 | 13.60 | 44 | 322114 | 61617 | 70544669 |
Disorientation | 153.59 | 13.60 | 37 | 322121 | 57886 | 70548400 |
Myalgia | 153.12 | 13.60 | 334 | 321824 | 167558 | 70438728 |
Ascites | 152.28 | 13.60 | 58 | 322100 | 67489 | 70538797 |
Liver function test increased | 151.95 | 13.60 | 416 | 321742 | 33431 | 70572855 |
Pancytopenia | 151.10 | 13.60 | 285 | 321873 | 150822 | 70455464 |
Pleural effusion | 150.86 | 13.60 | 231 | 321927 | 132633 | 70473653 |
Hypomagnesaemia | 148.98 | 13.60 | 9 | 322149 | 40755 | 70565531 |
Pulmonary oedema | 148.72 | 13.60 | 95 | 322063 | 82183 | 70524103 |
Limb deformity | 147.72 | 13.60 | 124 | 322034 | 3341 | 70602945 |
Melaena | 143.66 | 13.60 | 39 | 322119 | 56316 | 70549970 |
Dislocation of vertebra | 143.44 | 13.60 | 142 | 322016 | 4758 | 70601528 |
Haemorrhage | 143.16 | 13.60 | 103 | 322055 | 83712 | 70522574 |
Skin necrosis | 142.05 | 13.60 | 261 | 321897 | 16030 | 70590256 |
Dysphagia | 141.21 | 13.60 | 183 | 321975 | 112651 | 70493635 |
Restlessness | 140.78 | 13.60 | 14 | 322144 | 42114 | 70564172 |
Deformity | 140.75 | 13.60 | 181 | 321977 | 8116 | 70598170 |
Chills | 139.62 | 13.60 | 279 | 321879 | 144507 | 70461779 |
Haematuria | 139.35 | 13.60 | 57 | 322101 | 63516 | 70542770 |
Drug reaction with eosinophilia and systemic symptoms | 137.28 | 13.60 | 46 | 322112 | 57967 | 70548319 |
Hyperhidrosis | 136.17 | 13.60 | 243 | 321915 | 131343 | 70474943 |
Tuberculin test positive | 135.99 | 13.60 | 115 | 322043 | 3131 | 70603155 |
Hypervolaemia | 135.87 | 13.60 | 12 | 322146 | 39694 | 70566592 |
Abnormal behaviour | 135.43 | 13.60 | 5 | 322153 | 34704 | 70571582 |
Renal impairment | 134.86 | 13.60 | 282 | 321876 | 143655 | 70462631 |
Wrong technique in product usage process | 134.53 | 13.60 | 72 | 322086 | 68626 | 70537660 |
Sleep disorder | 133.54 | 13.60 | 650 | 321508 | 69222 | 70537064 |
Acute myocardial infarction | 133.32 | 13.60 | 83 | 322075 | 72804 | 70533482 |
Pneumonia | 133.29 | 13.60 | 1907 | 320251 | 594325 | 70011961 |
Oral mucosal exfoliation | 133.28 | 13.60 | 82 | 322076 | 1332 | 70604954 |
Blood creatinine increased | 132.45 | 13.60 | 282 | 321876 | 142719 | 70463567 |
Haemoglobin decreased | 129.78 | 13.60 | 486 | 321672 | 204673 | 70401613 |
Disturbance in attention | 129.35 | 13.60 | 20 | 322138 | 42874 | 70563412 |
Intentional self-injury | 129.18 | 13.60 | 3 | 322155 | 31647 | 70574639 |
Altered state of consciousness | 126.94 | 13.60 | 16 | 322142 | 40006 | 70566280 |
Urticaria | 125.96 | 13.60 | 1212 | 320946 | 161837 | 70444449 |
Coronary artery disease | 125.45 | 13.60 | 64 | 322094 | 62672 | 70543614 |
Ulcer | 125.17 | 13.60 | 326 | 321832 | 25428 | 70580858 |
Alanine aminotransferase abnormal | 124.63 | 13.60 | 168 | 321990 | 7891 | 70598395 |
Pancreatitis acute | 123.67 | 13.60 | 27 | 322131 | 45197 | 70561089 |
Palmar-plantar erythrodysaesthesia syndrome | 122.94 | 13.60 | 3 | 322155 | 30244 | 70576042 |
Generalised tonic-clonic seizure | 122.10 | 13.60 | 21 | 322137 | 41640 | 70564646 |
Sciatica | 122.02 | 13.60 | 314 | 321844 | 24313 | 70581973 |
Flushing | 120.61 | 13.60 | 117 | 322041 | 82055 | 70524231 |
Ventricular tachycardia | 119.40 | 13.60 | 13 | 322145 | 36410 | 70569876 |
Joint laxity | 119.40 | 13.60 | 93 | 322065 | 2246 | 70604040 |
Ankylosing spondylitis | 118.93 | 13.60 | 200 | 321958 | 11446 | 70594840 |
Joint injury | 118.90 | 13.60 | 329 | 321829 | 26603 | 70579683 |
Rectal haemorrhage | 117.62 | 13.60 | 77 | 322081 | 65754 | 70540532 |
Haematoma | 117.02 | 13.60 | 37 | 322121 | 48381 | 70557905 |
Musculoskeletal deformity | 115.51 | 13.60 | 70 | 322088 | 1105 | 70605181 |
Hallucination, visual | 115.25 | 13.60 | 4 | 322154 | 29333 | 70576953 |
Seronegative arthritis | 114.20 | 13.60 | 106 | 322052 | 3273 | 70603013 |
Joint effusion | 112.97 | 13.60 | 230 | 321928 | 15247 | 70591039 |
Physical disability | 112.83 | 13.60 | 98 | 322060 | 2769 | 70603517 |
Psychotic disorder | 112.73 | 13.60 | 18 | 322140 | 37683 | 70568603 |
Joint destruction | 112.49 | 13.60 | 122 | 322036 | 4556 | 70601730 |
Chronic kidney disease | 112.41 | 13.60 | 69 | 322089 | 60988 | 70545298 |
Joint arthroplasty | 109.93 | 13.60 | 92 | 322066 | 2468 | 70603818 |
Lymphocyte count decreased | 109.35 | 13.60 | 31 | 322127 | 43508 | 70562778 |
Cerebral infarction | 109.18 | 13.60 | 30 | 322128 | 42979 | 70563307 |
Drug withdrawal syndrome | 108.99 | 13.60 | 11 | 322147 | 32704 | 70573582 |
Epilepsy | 108.43 | 13.60 | 22 | 322136 | 38762 | 70567524 |
Night sweats | 108.13 | 13.60 | 439 | 321719 | 43245 | 70563041 |
Acute respiratory failure | 105.44 | 13.60 | 56 | 322102 | 53609 | 70552677 |
Red blood cell sedimentation rate | 104.26 | 13.60 | 120 | 322038 | 4790 | 70601496 |
Toxic epidermal necrolysis | 103.45 | 13.60 | 26 | 322132 | 39531 | 70566755 |
Drug level increased | 103.39 | 13.60 | 20 | 322138 | 36449 | 70569837 |
Arrhythmia | 102.59 | 13.60 | 64 | 322094 | 56079 | 70550207 |
Asthma | 102.29 | 13.60 | 250 | 321908 | 120543 | 70485743 |
Haemoptysis | 102.11 | 13.60 | 53 | 322105 | 51399 | 70554887 |
Product use in unapproved indication | 101.93 | 13.60 | 540 | 321618 | 206938 | 70399348 |
Fluid retention | 101.73 | 13.60 | 83 | 322075 | 63302 | 70542984 |
Urinary incontinence | 100.66 | 13.60 | 24 | 322134 | 37818 | 70568468 |
Neuropathy peripheral | 100.25 | 13.60 | 272 | 321886 | 126624 | 70479662 |
Haematochezia | 99.42 | 13.60 | 111 | 322047 | 72970 | 70533316 |
Dyspnoea exertional | 98.33 | 13.60 | 127 | 322031 | 78303 | 70527983 |
Accidental overdose | 98.02 | 13.60 | 20 | 322138 | 35101 | 70571185 |
Blood calcium decreased | 97.94 | 13.60 | 9 | 322149 | 28837 | 70577449 |
Aphasia | 97.71 | 13.60 | 37 | 322121 | 43212 | 70563074 |
Circulatory collapse | 97.36 | 13.60 | 21 | 322137 | 35453 | 70570833 |
Subdural haematoma | 97.21 | 13.60 | 10 | 322148 | 29288 | 70576998 |
Intentional product use issue | 96.70 | 13.60 | 901 | 321257 | 119241 | 70487045 |
Bone swelling | 95.94 | 13.60 | 69 | 322089 | 1471 | 70604815 |
Ejection fraction decreased | 95.88 | 13.60 | 13 | 322145 | 30749 | 70575537 |
Blood bilirubin increased | 95.44 | 13.60 | 79 | 322079 | 59822 | 70546464 |
Ear pain | 95.18 | 13.60 | 309 | 321849 | 27290 | 70578996 |
Diverticulitis | 95.16 | 13.60 | 409 | 321749 | 41325 | 70564961 |
Cardiac disorder | 95.11 | 13.60 | 78 | 322080 | 59337 | 70546949 |
Abdominal distension | 94.75 | 13.60 | 209 | 321949 | 104460 | 70501826 |
Dyskinesia | 94.71 | 13.60 | 34 | 322124 | 41040 | 70565246 |
Dysgeusia | 93.86 | 13.60 | 54 | 322104 | 49448 | 70556838 |
Adverse reaction | 93.85 | 13.60 | 152 | 322006 | 8430 | 70597856 |
Type 2 diabetes mellitus | 92.94 | 13.60 | 422 | 321736 | 43658 | 70562628 |
Loose body in joint | 92.90 | 13.60 | 63 | 322095 | 1218 | 70605068 |
Cardiogenic shock | 92.78 | 13.60 | 25 | 322133 | 36282 | 70570004 |
Inappropriate antidiuretic hormone secretion | 92.05 | 13.60 | 3 | 322155 | 23273 | 70583013 |
Exostosis | 91.75 | 13.60 | 202 | 321956 | 14143 | 70592143 |
Femur fracture | 90.94 | 13.60 | 365 | 321793 | 35767 | 70570519 |
Hypocalcaemia | 90.83 | 13.60 | 45 | 322113 | 44814 | 70561472 |
Sinus bradycardia | 90.16 | 13.60 | 4 | 322154 | 23619 | 70582667 |
Arthrodesis | 90.07 | 13.60 | 78 | 322080 | 2195 | 70604091 |
Blood urea increased | 90.06 | 13.60 | 48 | 322110 | 45861 | 70560425 |
Breast cancer stage III | 89.50 | 13.60 | 130 | 322028 | 6551 | 70599735 |
Surgical failure | 88.29 | 13.60 | 52 | 322106 | 777 | 70605509 |
Gastric disorder | 88.21 | 13.60 | 342 | 321816 | 32980 | 70573306 |
Presyncope | 88.03 | 13.60 | 30 | 322128 | 37408 | 70568878 |
Diabetic ketoacidosis | 87.83 | 13.60 | 18 | 322140 | 31494 | 70574792 |
Acute myeloid leukaemia | 87.65 | 13.60 | 17 | 322141 | 30923 | 70575363 |
Fine motor skill dysfunction | 87.43 | 13.60 | 111 | 322047 | 4913 | 70601373 |
Sinus tachycardia | 87.32 | 13.60 | 23 | 322135 | 33890 | 70572396 |
Delirium | 87.32 | 13.60 | 127 | 322031 | 74487 | 70531799 |
Foot operation | 87.21 | 13.60 | 109 | 322049 | 4748 | 70601538 |
Cholestasis | 86.88 | 13.60 | 55 | 322103 | 47817 | 70558469 |
Clostridium difficile colitis | 86.34 | 13.60 | 14 | 322144 | 28982 | 70577304 |
Labelled drug-drug interaction medication error | 86.17 | 13.60 | 6 | 322152 | 24121 | 70582165 |
Haemorrhage intracranial | 86.11 | 13.60 | 7 | 322151 | 24770 | 70581516 |
Poisoning | 85.78 | 13.60 | 4 | 322154 | 22618 | 70583668 |
Dysuria | 85.35 | 13.60 | 51 | 322107 | 45743 | 70560543 |
Shoulder arthroplasty | 85.03 | 13.60 | 85 | 322073 | 2882 | 70603404 |
Transient ischaemic attack | 84.46 | 13.60 | 52 | 322106 | 45892 | 70560394 |
Respiratory depression | 83.63 | 13.60 | 8 | 322150 | 24823 | 70581463 |
Neutropenic sepsis | 83.63 | 13.60 | 8 | 322150 | 24822 | 70581464 |
Tumour lysis syndrome | 83.60 | 13.60 | 3 | 322155 | 21357 | 70584929 |
Tendonitis | 83.00 | 13.60 | 255 | 321903 | 21867 | 70584419 |
Chronic obstructive pulmonary disease | 82.46 | 13.60 | 141 | 322017 | 77500 | 70528786 |
Wrist deformity | 82.21 | 13.60 | 68 | 322090 | 1794 | 70604492 |
Product quality issue | 82.05 | 13.60 | 19 | 322139 | 30542 | 70575744 |
Hemiparesis | 81.68 | 13.60 | 21 | 322137 | 31448 | 70574838 |
Fatigue | 81.54 | 13.60 | 4547 | 317611 | 819772 | 69786514 |
Withdrawal syndrome | 81.35 | 13.60 | 9 | 322149 | 24895 | 70581391 |
Basal cell carcinoma | 81.31 | 13.60 | 336 | 321822 | 33362 | 70572924 |
Deep vein thrombosis | 80.41 | 13.60 | 248 | 321910 | 110794 | 70495492 |
Oxygen saturation decreased | 80.15 | 13.60 | 266 | 321892 | 116163 | 70490123 |
Myoclonus | 80.12 | 13.60 | 12 | 322146 | 26343 | 70579943 |
Contusion | 80.07 | 13.60 | 912 | 321246 | 127124 | 70479162 |
Premature delivery | 80.03 | 13.60 | 4 | 322154 | 21300 | 70584986 |
Full blood count decreased | 79.78 | 13.60 | 8 | 322150 | 23910 | 70582376 |
Status epilepticus | 79.77 | 13.60 | 9 | 322149 | 24517 | 70581769 |
Atlantoaxial instability | 79.42 | 13.60 | 35 | 322123 | 270 | 70606016 |
Limb discomfort | 78.73 | 13.60 | 305 | 321853 | 29400 | 70576886 |
Ileus | 78.56 | 13.60 | 9 | 322149 | 24228 | 70582058 |
Intestinal obstruction | 78.53 | 13.60 | 39 | 322119 | 38786 | 70567500 |
Upper gastrointestinal haemorrhage | 78.32 | 13.60 | 36 | 322122 | 37441 | 70568845 |
Mineral metabolism disorder | 77.91 | 13.60 | 35 | 322123 | 284 | 70606002 |
Angioedema | 77.33 | 13.60 | 114 | 322044 | 66496 | 70539790 |
Dry skin | 77.12 | 13.60 | 84 | 322074 | 55847 | 70550439 |
Pulmonary hypertension | 77.12 | 13.60 | 59 | 322099 | 46477 | 70559809 |
Tongue disorder | 76.52 | 13.60 | 179 | 321979 | 13048 | 70593238 |
Eosinophilia | 76.42 | 13.60 | 44 | 322114 | 40275 | 70566011 |
Suicidal ideation | 76.13 | 13.60 | 124 | 322034 | 69472 | 70536814 |
Depressed mood | 75.94 | 13.60 | 53 | 322105 | 43767 | 70562519 |
Pallor | 75.84 | 13.60 | 46 | 322112 | 40928 | 70565358 |
Pericardial effusion | 75.80 | 13.60 | 48 | 322110 | 41728 | 70564558 |
Intervertebral disc space narrowing | 75.54 | 13.60 | 60 | 322098 | 1492 | 70604794 |
Irritability | 74.93 | 13.60 | 40 | 322118 | 38185 | 70568101 |
Haematemesis | 74.52 | 13.60 | 67 | 322091 | 48730 | 70557556 |
Sensitivity to weather change | 74.06 | 13.60 | 126 | 322032 | 7279 | 70599007 |
Myocardial infarction | 73.96 | 13.60 | 466 | 321692 | 171179 | 70435107 |
Hospitalisation | 73.80 | 13.60 | 166 | 321992 | 82402 | 70523884 |
Agranulocytosis | 73.54 | 13.60 | 46 | 322112 | 40252 | 70566034 |
Full blood count abnormal | 73.23 | 13.60 | 31 | 322127 | 33847 | 70572439 |
Small intestinal obstruction | 73.20 | 13.60 | 12 | 322146 | 24643 | 70581643 |
Muscle spasticity | 72.98 | 13.60 | 226 | 321932 | 19463 | 70586823 |
Blood potassium decreased | 72.60 | 13.60 | 52 | 322106 | 42369 | 70563917 |
Shock | 72.59 | 13.60 | 47 | 322111 | 40378 | 70565908 |
Ventricular fibrillation | 72.49 | 13.60 | 17 | 322141 | 27094 | 70579192 |
Renal tubular necrosis | 71.72 | 13.60 | 10 | 322148 | 23161 | 70583125 |
Hyperbilirubinaemia | 71.62 | 13.60 | 9 | 322149 | 22559 | 70583727 |
Spinal instability | 71.54 | 13.60 | 35 | 322123 | 351 | 70605935 |
Bacteraemia | 71.54 | 13.60 | 22 | 322136 | 29287 | 70576999 |
Mucosal inflammation | 71.34 | 13.60 | 124 | 322034 | 67726 | 70538560 |
Ankle deformity | 71.29 | 13.60 | 42 | 322116 | 628 | 70605658 |
Hypothermia | 71.07 | 13.60 | 6 | 322152 | 20588 | 70585698 |
Bone cyst | 70.95 | 13.60 | 76 | 322082 | 2798 | 70603488 |
Product administration error | 70.56 | 13.60 | 23 | 322135 | 29500 | 70576786 |
Bone pain | 70.44 | 13.60 | 76 | 322082 | 50746 | 70555540 |
Dystonia | 70.09 | 13.60 | 5 | 322153 | 19701 | 70586585 |
Deafness transitory | 69.65 | 13.60 | 47 | 322111 | 901 | 70605385 |
Intestinal sepsis | 69.52 | 13.60 | 44 | 322114 | 753 | 70605533 |
Thyroid neoplasm | 69.46 | 13.60 | 76 | 322082 | 2867 | 70603419 |
Bone marrow failure | 69.37 | 13.60 | 72 | 322086 | 48938 | 70557348 |
Torsade de pointes | 69.36 | 13.60 | 3 | 322155 | 18113 | 70588173 |
Drug use disorder | 69.07 | 13.60 | 129 | 322029 | 8022 | 70598264 |
Terminal state | 68.94 | 13.60 | 95 | 322063 | 4557 | 70601729 |
Leukocytosis | 68.71 | 13.60 | 48 | 322110 | 39620 | 70566666 |
Bone density abnormal | 68.57 | 13.60 | 75 | 322083 | 2828 | 70603458 |
Dementia | 68.41 | 13.60 | 10 | 322148 | 22355 | 70583931 |
Pancreatitis | 68.22 | 13.60 | 112 | 322046 | 62556 | 70543730 |
Head injury | 67.99 | 13.60 | 35 | 322123 | 34106 | 70572180 |
Retinitis | 67.83 | 13.60 | 89 | 322069 | 4071 | 70602215 |
Flatulence | 67.74 | 13.60 | 45 | 322113 | 38136 | 70568150 |
Product prescribing error | 67.65 | 13.60 | 47 | 322111 | 38905 | 70567381 |
Blood sodium decreased | 67.59 | 13.60 | 28 | 322130 | 30970 | 70575316 |
Hepatic encephalopathy | 67.40 | 13.60 | 10 | 322148 | 22108 | 70584178 |
Mitral valve incompetence | 67.18 | 13.60 | 19 | 322139 | 26709 | 70579577 |
Cough | 66.87 | 13.60 | 1057 | 321101 | 324320 | 70281966 |
Metastases to bone | 66.19 | 13.60 | 11 | 322147 | 22365 | 70583921 |
Disseminated intravascular coagulation | 66.09 | 13.60 | 35 | 322123 | 33563 | 70572723 |
Therapy non-responder | 66.03 | 13.60 | 585 | 321573 | 76330 | 70529956 |
Blood iron abnormal | 65.97 | 13.60 | 50 | 322108 | 1158 | 70605128 |
Lupus-like syndrome | 65.71 | 13.60 | 155 | 322003 | 11360 | 70594926 |
Gastrooesophageal reflux disease | 65.68 | 13.60 | 203 | 321955 | 90636 | 70515650 |
International normalised ratio fluctuation | 65.55 | 13.60 | 77 | 322081 | 3142 | 70603144 |
X-ray abnormal | 65.50 | 13.60 | 69 | 322089 | 2491 | 70603795 |
Creatinine renal clearance decreased | 65.35 | 13.60 | 3 | 322155 | 17197 | 70589089 |
Polyomavirus-associated nephropathy | 65.32 | 13.60 | 98 | 322060 | 5085 | 70601201 |
Mania | 65.24 | 13.60 | 3 | 322155 | 17171 | 70589115 |
Synovial cyst | 65.09 | 13.60 | 131 | 322027 | 8611 | 70597675 |
Confusional state | 64.96 | 13.60 | 905 | 321253 | 283493 | 70322793 |
Anuria | 64.46 | 13.60 | 7 | 322151 | 19646 | 70586640 |
Weight increased | 64.31 | 13.60 | 1497 | 320661 | 240834 | 70365452 |
Anti-cyclic citrullinated peptide antibody | 64.05 | 13.60 | 78 | 322080 | 3307 | 70602979 |
Brain oedema | 63.99 | 13.60 | 14 | 322144 | 23404 | 70582882 |
Metastases to liver | 63.93 | 13.60 | 19 | 322139 | 25859 | 70580427 |
Exposure during pregnancy | 63.76 | 13.60 | 644 | 321514 | 87073 | 70519213 |
Therapy cessation | 63.47 | 13.60 | 37 | 322121 | 33639 | 70572647 |
Obstructive airways disorder | 63.02 | 13.60 | 20 | 322138 | 26093 | 70580193 |
Bone disorder | 62.29 | 13.60 | 198 | 321960 | 17292 | 70588994 |
Infusion site reaction | 62.17 | 13.60 | 70 | 322088 | 2727 | 70603559 |
Hallucination, auditory | 61.48 | 13.60 | 6 | 322152 | 18322 | 70587964 |
Stevens-Johnson syndrome | 61.47 | 13.60 | 44 | 322114 | 35863 | 70570423 |
Aspiration | 61.41 | 13.60 | 5 | 322153 | 17670 | 70588616 |
Multiple fractures | 61.03 | 13.60 | 110 | 322048 | 6655 | 70599631 |
Neck deformity | 60.98 | 13.60 | 56 | 322102 | 1705 | 70604581 |
Sudden death | 60.89 | 13.60 | 11 | 322147 | 21053 | 70585233 |
Retinal toxicity | 60.87 | 13.60 | 50 | 322108 | 1306 | 70604980 |
Systemic lupus erythematosus rash | 60.79 | 13.60 | 54 | 322104 | 1573 | 70604713 |
Abdominal pain lower | 60.70 | 13.60 | 26 | 322132 | 28190 | 70578096 |
Joint dislocation | 60.69 | 13.60 | 174 | 321984 | 14357 | 70591929 |
Tachypnoea | 60.64 | 13.60 | 27 | 322131 | 28611 | 70577675 |
Incorrect dose administered | 60.56 | 13.60 | 133 | 322025 | 66586 | 70539700 |
Coordination abnormal | 60.41 | 13.60 | 3 | 322155 | 16063 | 70590223 |
Device dislocation | 60.41 | 13.60 | 14 | 322144 | 22493 | 70583793 |
Spinal column injury | 60.30 | 13.60 | 59 | 322099 | 1948 | 70604338 |
Muscle rigidity | 60.27 | 13.60 | 7 | 322151 | 18643 | 70587643 |
Myopathy | 60.11 | 13.60 | 7 | 322151 | 18605 | 70587681 |
Gastrointestinal pain | 59.89 | 13.60 | 123 | 322035 | 8204 | 70598082 |
Bloody discharge | 59.80 | 13.60 | 55 | 322103 | 1678 | 70604608 |
Colitis | 59.76 | 13.60 | 125 | 322033 | 63689 | 70542597 |
White blood cell count increased | 59.66 | 13.60 | 143 | 322015 | 69430 | 70536856 |
Body temperature increased | 59.30 | 13.60 | 346 | 321812 | 39488 | 70566798 |
Haemodynamic instability | 58.63 | 13.60 | 3 | 322155 | 15655 | 70590631 |
Electrolyte imbalance | 57.39 | 13.60 | 25 | 322133 | 26836 | 70579450 |
Dactylitis | 56.80 | 13.60 | 60 | 322098 | 2173 | 70604113 |
Acidosis | 56.25 | 13.60 | 8 | 322150 | 18255 | 70588031 |
Hepatic enzyme abnormal | 56.19 | 13.60 | 102 | 322056 | 6205 | 70600081 |
Pollakiuria | 55.98 | 13.60 | 42 | 322116 | 33419 | 70572867 |
Cholelithiasis | 55.95 | 13.60 | 80 | 322078 | 47260 | 70559026 |
Atrial flutter | 55.85 | 13.60 | 12 | 322146 | 20315 | 70585971 |
Injection site reaction | 55.81 | 13.60 | 403 | 321755 | 49449 | 70556837 |
Hepatic failure | 55.55 | 13.60 | 111 | 322047 | 57514 | 70548772 |
Extrapyramidal disorder | 55.50 | 13.60 | 13 | 322145 | 20737 | 70585549 |
Device issue | 55.20 | 13.60 | 20 | 322138 | 24005 | 70582281 |
Toxic skin eruption | 55.20 | 13.60 | 12 | 322146 | 20150 | 70586136 |
Visual acuity reduced | 55.08 | 13.60 | 29 | 322129 | 27901 | 70578385 |
Gastritis | 55.07 | 13.60 | 73 | 322085 | 44518 | 70561768 |
Ovarian neoplasm | 55.01 | 13.60 | 34 | 322124 | 557 | 70605729 |
Mydriasis | 54.94 | 13.60 | 5 | 322153 | 16148 | 70590138 |
Rash erythematous | 54.84 | 13.60 | 94 | 322064 | 51624 | 70554662 |
Spinal stenosis | 54.13 | 13.60 | 168 | 321990 | 14485 | 70591801 |
Diarrhoea | 54.07 | 13.60 | 2959 | 319199 | 780382 | 69825904 |
Osteosclerosis | 53.92 | 13.60 | 75 | 322083 | 3630 | 70602656 |
Cyanosis | 53.86 | 13.60 | 19 | 322139 | 23187 | 70583099 |
Speech disorder | 53.57 | 13.60 | 92 | 322066 | 50488 | 70555798 |
Delusion | 53.30 | 13.60 | 11 | 322147 | 19154 | 70587132 |
Angina pectoris | 53.10 | 13.60 | 86 | 322072 | 48297 | 70557989 |
Hypophosphataemia | 53.07 | 13.60 | 6 | 322152 | 16320 | 70589966 |
Face oedema | 53 | 13.60 | 25 | 322133 | 25614 | 70580672 |
Drug ineffective for unapproved indication | 53.00 | 13.60 | 58 | 322100 | 38480 | 70567806 |
Acute coronary syndrome | 52.88 | 13.60 | 13 | 322145 | 20066 | 70586220 |
Pulmonary arterial hypertension | 52.74 | 13.60 | 43 | 322115 | 32812 | 70573474 |
Aplastic anaemia | 52.25 | 13.60 | 7 | 322151 | 16709 | 70589577 |
Heart rate increased | 52.24 | 13.60 | 276 | 321882 | 105872 | 70500414 |
Fear | 51.92 | 13.60 | 15 | 322143 | 20796 | 70585490 |
Peritonitis | 51.82 | 13.60 | 27 | 322131 | 26132 | 70580154 |
Cellulitis | 51.65 | 13.60 | 252 | 321906 | 98676 | 70507610 |
Lower gastrointestinal haemorrhage | 51.60 | 13.60 | 4 | 322154 | 14716 | 70591570 |
Investigation abnormal | 51.49 | 13.60 | 52 | 322106 | 1785 | 70604501 |
Supraventricular tachycardia | 51.45 | 13.60 | 13 | 322145 | 19697 | 70586589 |
Electrocardiogram abnormal | 51.36 | 13.60 | 4 | 322154 | 14660 | 70591626 |
Fear of injection | 50.90 | 13.60 | 101 | 322057 | 6571 | 70599715 |
Mouth ulceration | 50.90 | 13.60 | 298 | 321860 | 34051 | 70572235 |
Cardiac failure acute | 50.84 | 13.60 | 9 | 322149 | 17478 | 70588808 |
Atrioventricular block complete | 50.76 | 13.60 | 5 | 322153 | 15158 | 70591128 |
Nausea | 50.75 | 13.60 | 3264 | 318894 | 848824 | 69757462 |
Left ventricular dysfunction | 50.58 | 13.60 | 10 | 322148 | 17947 | 70588339 |
Ataxia | 50.58 | 13.60 | 21 | 322137 | 23196 | 70583090 |
Haemodialysis | 50.35 | 13.60 | 9 | 322149 | 17357 | 70588929 |
Extremity contracture | 50.25 | 13.60 | 49 | 322109 | 1611 | 70604675 |
Lower limb fracture | 50.12 | 13.60 | 179 | 321979 | 16593 | 70589693 |
Polyarthritis | 50.07 | 13.60 | 134 | 322024 | 10622 | 70595664 |
Therapy interrupted | 50.03 | 13.60 | 25 | 322133 | 24777 | 70581509 |
Emotional distress | 50.01 | 13.60 | 57 | 322101 | 37131 | 70569155 |
Ischaemic stroke | 49.89 | 13.60 | 40 | 322118 | 30780 | 70575506 |
Tubulointerstitial nephritis | 49.81 | 13.60 | 46 | 322112 | 33030 | 70573256 |
Renal injury | 49.69 | 13.60 | 7 | 322151 | 16087 | 70590199 |
Hypophagia | 49.38 | 13.60 | 70 | 322088 | 41500 | 70564786 |
Acute generalised exanthematous pustulosis | 49.21 | 13.60 | 6 | 322152 | 15391 | 70590895 |
Cardiomegaly | 49.12 | 13.60 | 25 | 322133 | 24520 | 70581766 |
Diplopia | 48.83 | 13.60 | 34 | 322124 | 28113 | 70578173 |
Product substitution issue | 48.73 | 13.60 | 12 | 322146 | 18501 | 70587785 |
Localised infection | 48.70 | 13.60 | 287 | 321871 | 32871 | 70573415 |
Pemphigoid | 48.62 | 13.60 | 4 | 322154 | 14018 | 70592268 |
Prostate cancer | 48.53 | 13.60 | 42 | 322116 | 31121 | 70575165 |
Muscle twitching | 48.18 | 13.60 | 15 | 322143 | 19812 | 70586474 |
Transfusion | 48.07 | 13.60 | 13 | 322145 | 18823 | 70587463 |
Tinnitus | 48.05 | 13.60 | 56 | 322102 | 36120 | 70570166 |
Myelodysplastic syndrome | 47.79 | 13.60 | 39 | 322119 | 29746 | 70576540 |
Metastases to central nervous system | 47.70 | 13.60 | 6 | 322152 | 15028 | 70591258 |
Chondropathy | 47.62 | 13.60 | 57 | 322101 | 2373 | 70603913 |
Skin exfoliation | 47.45 | 13.60 | 93 | 322065 | 48533 | 70557753 |
Vasculitic rash | 47.26 | 13.60 | 52 | 322106 | 1974 | 70604312 |
Incontinence | 47.23 | 13.60 | 3 | 322155 | 13025 | 70593261 |
Accidental exposure to product | 47.20 | 13.60 | 35 | 322123 | 28016 | 70578270 |
Haemorrhoids | 46.98 | 13.60 | 29 | 322129 | 25559 | 70580727 |
Metastases to lung | 46.81 | 13.60 | 9 | 322149 | 16475 | 70589811 |
Urine output decreased | 46.66 | 13.60 | 10 | 322148 | 16960 | 70589326 |
Bursitis | 46.62 | 13.60 | 242 | 321916 | 26431 | 70579855 |
Pulmonary thrombosis | 46.61 | 13.60 | 134 | 322024 | 11074 | 70595212 |
Malnutrition | 46.53 | 13.60 | 17 | 322141 | 20300 | 70585986 |
Palpitations | 46.50 | 13.60 | 303 | 321855 | 110450 | 70495836 |
Immune thrombocytopenia | 46.17 | 13.60 | 9 | 322149 | 16315 | 70589971 |
Mycotic allergy | 46.02 | 13.60 | 39 | 322119 | 1065 | 70605221 |
Pulmonary toxicity | 45.78 | 13.60 | 130 | 322028 | 10668 | 70595618 |
Nail disorder | 45.67 | 13.60 | 127 | 322031 | 10297 | 70595989 |
Acute respiratory distress syndrome | 45.58 | 13.60 | 73 | 322085 | 41181 | 70565105 |
Osteoporotic fracture | 45.50 | 13.60 | 70 | 322088 | 3714 | 70602572 |
Bronchitis chronic | 45.30 | 13.60 | 73 | 322085 | 4031 | 70602255 |
Weight decreased | 45.27 | 13.60 | 1069 | 321089 | 309419 | 70296867 |
Anticipatory anxiety | 45.22 | 13.60 | 37 | 322121 | 961 | 70605325 |
Panic attack | 45.06 | 13.60 | 22 | 322136 | 22097 | 70584189 |
Fracture delayed union | 44.86 | 13.60 | 51 | 322107 | 2008 | 70604278 |
Gait inability | 44.80 | 13.60 | 367 | 321791 | 46808 | 70559478 |
Maternal exposure timing unspecified | 44.29 | 13.60 | 75 | 322083 | 4316 | 70601970 |
Myocarditis | 44.28 | 13.60 | 15 | 322143 | 18778 | 70587508 |
Wrist surgery | 44.15 | 13.60 | 33 | 322125 | 748 | 70605538 |
Mental disorder | 44.05 | 13.60 | 38 | 322120 | 28202 | 70578084 |
Hyperthyroidism | 44.04 | 13.60 | 18 | 322140 | 20073 | 70586213 |
Injection site hypersensitivity | 43.99 | 13.60 | 47 | 322111 | 1725 | 70604561 |
Onychomycosis | 43.93 | 13.60 | 97 | 322061 | 6804 | 70599482 |
Ventricular extrasystoles | 43.91 | 13.60 | 14 | 322144 | 18212 | 70588074 |
Hypoalbuminaemia | 43.79 | 13.60 | 16 | 322142 | 19106 | 70587180 |
Nocturia | 43.69 | 13.60 | 3 | 322155 | 12201 | 70594085 |
Device related infection | 43.64 | 13.60 | 49 | 322109 | 32136 | 70574150 |
Blood glucose decreased | 43.50 | 13.60 | 28 | 322130 | 24131 | 70582155 |
Drug tolerance | 43.49 | 13.60 | 101 | 322057 | 7327 | 70598959 |
Shock haemorrhagic | 43.46 | 13.60 | 14 | 322144 | 18092 | 70588194 |
Sarcoidosis | 43.15 | 13.60 | 94 | 322064 | 6533 | 70599753 |
Mycobacterium tuberculosis complex test positive | 42.92 | 13.60 | 53 | 322105 | 2280 | 70604006 |
Lip swelling | 42.82 | 13.60 | 55 | 322103 | 33999 | 70572287 |
Depression | 42.66 | 13.60 | 641 | 321517 | 198333 | 70407953 |
Hair follicle tumour benign | 42.65 | 13.60 | 26 | 322132 | 415 | 70605871 |
Oesophagitis | 42.53 | 13.60 | 25 | 322133 | 22627 | 70583659 |
Vertigo | 42.49 | 13.60 | 144 | 322014 | 62499 | 70543787 |
Tuberculosis | 42.28 | 13.60 | 156 | 322002 | 14692 | 70591594 |
Granuloma | 42.20 | 13.60 | 102 | 322056 | 7593 | 70598693 |
Cutaneous vasculitis | 41.92 | 13.60 | 98 | 322060 | 7140 | 70599146 |
Appendicitis | 41.86 | 13.60 | 12 | 322146 | 16721 | 70589565 |
Red cell distribution width decreased | 41.85 | 13.60 | 44 | 322114 | 1585 | 70604701 |
Arteriosclerosis coronary artery | 41.74 | 13.60 | 11 | 322147 | 16204 | 70590082 |
Pruritus allergic | 41.68 | 13.60 | 37 | 322121 | 1077 | 70605209 |
Erectile dysfunction | 41.63 | 13.60 | 6 | 322152 | 13556 | 70592730 |
Troponin increased | 41.40 | 13.60 | 12 | 322146 | 16602 | 70589684 |
Jaundice | 41.39 | 13.60 | 105 | 322053 | 50003 | 70556283 |
Oliguria | 41.12 | 13.60 | 9 | 322149 | 15042 | 70591244 |
Myocardial ischaemia | 40.97 | 13.60 | 30 | 322128 | 24170 | 70582116 |
Clostridium difficile infection | 40.74 | 13.60 | 71 | 322087 | 38745 | 70567541 |
Angina unstable | 40.50 | 13.60 | 11 | 322147 | 15882 | 70590404 |
Herpes zoster | 40.45 | 13.60 | 577 | 321581 | 84658 | 70521628 |
Secretion discharge | 40.34 | 13.60 | 140 | 322018 | 12793 | 70593493 |
Blood magnesium decreased | 40.29 | 13.60 | 9 | 322149 | 14832 | 70591454 |
Hepatocellular injury | 40.10 | 13.60 | 94 | 322064 | 45997 | 70560289 |
Lyme disease | 39.85 | 13.60 | 57 | 322101 | 2832 | 70603454 |
Colitis ischaemic | 39.55 | 13.60 | 8 | 322150 | 14129 | 70592157 |
Hypotonia | 39.49 | 13.60 | 4 | 322154 | 11861 | 70594425 |
Coagulopathy | 39.48 | 13.60 | 56 | 322102 | 33193 | 70573093 |
Skin discolouration | 39.43 | 13.60 | 68 | 322090 | 37257 | 70569029 |
Rash maculo-papular | 39.41 | 13.60 | 109 | 322049 | 50436 | 70555850 |
Transaminases abnormal | 39.37 | 13.60 | 31 | 322127 | 761 | 70605525 |
Joint space narrowing | 39.27 | 13.60 | 24 | 322134 | 385 | 70605901 |
Mean platelet volume decreased | 39.10 | 13.60 | 50 | 322108 | 2229 | 70604057 |
Vascular access complication | 39.02 | 13.60 | 44 | 322114 | 1717 | 70604569 |
Subarachnoid haemorrhage | 38.83 | 13.60 | 20 | 322138 | 19484 | 70586802 |
Blood loss anaemia | 38.72 | 13.60 | 9 | 322149 | 14432 | 70591854 |
Allergic oedema | 38.50 | 13.60 | 30 | 322128 | 725 | 70605561 |
Colitis ulcerative | 38.46 | 13.60 | 59 | 322099 | 33864 | 70572422 |
Bronchopulmonary aspergillosis | 38.28 | 13.60 | 24 | 322134 | 20978 | 70585308 |
Emotional disorder | 38.03 | 13.60 | 7 | 322151 | 13219 | 70593067 |
Prothrombin time prolonged | 38.01 | 13.60 | 13 | 322145 | 16177 | 70590109 |
Device difficult to use | 37.88 | 13.60 | 3 | 322155 | 10846 | 70595440 |
Incorrect product administration duration | 37.78 | 13.60 | 3 | 322155 | 10821 | 70595465 |
Liver injury | 37.77 | 13.60 | 317 | 321841 | 40718 | 70565568 |
Pulmonary haemorrhage | 37.71 | 13.60 | 8 | 322150 | 13665 | 70592621 |
Cytology abnormal | 37.69 | 13.60 | 22 | 322136 | 323 | 70605963 |
Ankle arthroplasty | 37.67 | 13.60 | 36 | 322122 | 1154 | 70605132 |
Demyelination | 37.65 | 13.60 | 94 | 322064 | 7142 | 70599144 |
Infiltration anaesthesia | 37.42 | 13.60 | 17 | 322141 | 142 | 70606144 |
Faeces discoloured | 37.25 | 13.60 | 40 | 322118 | 26769 | 70579517 |
Atelectasis | 37.22 | 13.60 | 46 | 322112 | 28916 | 70577370 |
Neutrophil count increased | 37.21 | 13.60 | 40 | 322118 | 26755 | 70579531 |
Foot fracture | 37.19 | 13.60 | 182 | 321976 | 19418 | 70586868 |
Paraesthesia | 36.91 | 13.60 | 453 | 321705 | 145084 | 70461202 |
Nightmare | 36.82 | 13.60 | 28 | 322130 | 22128 | 70584158 |
Facet joint syndrome | 36.76 | 13.60 | 84 | 322074 | 6029 | 70600257 |
Pulmonary mass | 36.74 | 13.60 | 223 | 321935 | 25810 | 70580476 |
C-reactive protein | 36.33 | 13.60 | 46 | 322112 | 2030 | 70604256 |
Pustular psoriasis | 36.21 | 13.60 | 71 | 322087 | 4579 | 70601707 |
Eosinophil count increased | 36.13 | 13.60 | 12 | 322146 | 15210 | 70591076 |
Adjustment disorder with depressed mood | 35.99 | 13.60 | 67 | 322091 | 4156 | 70602130 |
Atrioventricular block | 35.88 | 13.60 | 7 | 322151 | 12681 | 70593605 |
Tricuspid valve incompetence | 35.87 | 13.60 | 18 | 322140 | 17799 | 70588487 |
Ear infection | 35.81 | 13.60 | 236 | 321922 | 28100 | 70578186 |
Inappropriate schedule of product administration | 35.78 | 13.60 | 314 | 321844 | 107241 | 70499045 |
Lymphopenia | 35.64 | 13.60 | 43 | 322115 | 27316 | 70578970 |
Drug level decreased | 35.62 | 13.60 | 7 | 322151 | 12617 | 70593669 |
Skin papilloma | 35.56 | 13.60 | 77 | 322081 | 5329 | 70600957 |
Labile blood pressure | 35.36 | 13.60 | 46 | 322112 | 2086 | 70604200 |
Muscular weakness | 35.30 | 13.60 | 430 | 321728 | 137906 | 70468380 |
Eye pain | 35.23 | 13.60 | 63 | 322095 | 34039 | 70572247 |
Failure to thrive | 35.15 | 13.60 | 4 | 322154 | 10825 | 70595461 |
Hypercalcaemia | 35.11 | 13.60 | 272 | 321886 | 34113 | 70572173 |
Sleep apnoea syndrome | 35.10 | 13.60 | 59 | 322099 | 32654 | 70573632 |
Chromaturia | 35.10 | 13.60 | 33 | 322125 | 23495 | 70582791 |
Apnoea | 35.07 | 13.60 | 4 | 322154 | 10805 | 70595481 |
Hepatic cytolysis | 34.89 | 13.60 | 22 | 322136 | 19170 | 70587116 |
Wound infection | 34.80 | 13.60 | 165 | 321993 | 17377 | 70588909 |
Vaginal haemorrhage | 34.75 | 13.60 | 25 | 322133 | 20327 | 70585959 |
Acute pulmonary oedema | 34.71 | 13.60 | 9 | 322149 | 13403 | 70592883 |
Cholecystitis | 34.61 | 13.60 | 26 | 322132 | 20675 | 70585611 |
Lacrimation increased | 34.57 | 13.60 | 24 | 322134 | 19875 | 70586411 |
Dialysis | 34.41 | 13.60 | 18 | 322140 | 17384 | 70588902 |
Klebsiella infection | 34.39 | 13.60 | 11 | 322147 | 14281 | 70592005 |
Underdose | 34.38 | 13.60 | 50 | 322108 | 29333 | 70576953 |
Pneumonia fungal | 34.07 | 13.60 | 3 | 322155 | 9950 | 70596336 |
Bradyphrenia | 34.04 | 13.60 | 3 | 322155 | 9943 | 70596343 |
Mental impairment | 33.90 | 13.60 | 18 | 322140 | 17237 | 70589049 |
Epstein-Barr virus infection | 33.88 | 13.60 | 9 | 322149 | 13189 | 70593097 |
Coronary artery stenosis | 33.83 | 13.60 | 6 | 322152 | 11638 | 70594648 |
Cardiomyopathy | 33.78 | 13.60 | 42 | 322116 | 26331 | 70579955 |
Myelosuppression | 33.63 | 13.60 | 53 | 322105 | 30092 | 70576194 |
Impaired gastric emptying | 33.56 | 13.60 | 107 | 322051 | 9359 | 70596927 |
Neck pain | 33.55 | 13.60 | 456 | 321702 | 66201 | 70540085 |
Hypermobility syndrome | 33.52 | 13.60 | 24 | 322134 | 508 | 70605778 |
Infusion site pain | 33.51 | 13.60 | 6 | 322152 | 11558 | 70594728 |
Hepatotoxicity | 33.44 | 13.60 | 326 | 321832 | 43660 | 70562626 |
Activated partial thromboplastin time prolonged | 33.21 | 13.60 | 10 | 322148 | 13495 | 70592791 |
Cytomegalovirus infection | 33.08 | 13.60 | 83 | 322075 | 39675 | 70566611 |
Respiratory acidosis | 32.87 | 13.60 | 4 | 322154 | 10277 | 70596009 |
Salivary hypersecretion | 32.83 | 13.60 | 9 | 322149 | 12916 | 70593370 |
Mass excision | 32.82 | 13.60 | 20 | 322138 | 319 | 70605967 |
Sensory disturbance | 32.66 | 13.60 | 11 | 322147 | 13821 | 70592465 |
Hepatocellular carcinoma | 32.57 | 13.60 | 4 | 322154 | 10204 | 70596082 |
Multiple allergies | 32.48 | 13.60 | 93 | 322065 | 7667 | 70598619 |
Diabetes mellitus inadequate control | 32.35 | 13.60 | 33 | 322125 | 22612 | 70583674 |
Paraesthesia oral | 31.92 | 13.60 | 15 | 322143 | 15402 | 70590884 |
Diastolic dysfunction | 31.87 | 13.60 | 3 | 322155 | 9430 | 70596856 |
Aspergillus infection | 31.77 | 13.60 | 21 | 322137 | 17847 | 70588439 |
Mean cell volume decreased | 31.75 | 13.60 | 65 | 322093 | 4325 | 70601961 |
Rash pruritic | 31.74 | 13.60 | 431 | 321727 | 62560 | 70543726 |
Joint lock | 31.70 | 13.60 | 52 | 322106 | 2915 | 70603371 |
Osteopenia | 31.65 | 13.60 | 155 | 322003 | 16542 | 70589744 |
Pulse absent | 31.44 | 13.60 | 3 | 322155 | 9327 | 70596959 |
Joint ankylosis | 31.07 | 13.60 | 37 | 322121 | 1532 | 70604754 |
Polyuria | 31.07 | 13.60 | 11 | 322147 | 13395 | 70592891 |
Hypercholesterolaemia | 30.71 | 13.60 | 163 | 321995 | 17954 | 70588332 |
Diffuse large B-cell lymphoma | 30.68 | 13.60 | 11 | 322147 | 13291 | 70592995 |
Multiple sclerosis | 30.61 | 13.60 | 42 | 322116 | 25243 | 70581043 |
Bronchospasm | 30.57 | 13.60 | 35 | 322123 | 22757 | 70583529 |
Enterococcal infection | 30.48 | 13.60 | 14 | 322144 | 14568 | 70591718 |
Hyperthermia | 30.46 | 13.60 | 19 | 322139 | 16652 | 70589634 |
Hepatic cancer | 30.39 | 13.60 | 4 | 322154 | 9679 | 70596607 |
Burning sensation | 30.38 | 13.60 | 130 | 322028 | 52740 | 70553546 |
Hiccups | 30.26 | 13.60 | 3 | 322155 | 9049 | 70597237 |
Heparin-induced thrombocytopenia | 30.20 | 13.60 | 3 | 322155 | 9034 | 70597252 |
Complication associated with device | 29.98 | 13.60 | 17 | 322141 | 15696 | 70590590 |
Carpal tunnel syndrome | 29.97 | 13.60 | 155 | 322003 | 16902 | 70589384 |
Anal incontinence | 29.84 | 13.60 | 19 | 322139 | 16471 | 70589815 |
Brain injury | 29.72 | 13.60 | 6 | 322152 | 10611 | 70595675 |
Bundle branch block right | 29.69 | 13.60 | 6 | 322152 | 10604 | 70595682 |
Hemiplegia | 29.58 | 13.60 | 13 | 322145 | 13882 | 70592404 |
Embolism | 29.52 | 13.60 | 11 | 322147 | 12977 | 70593309 |
Purpura | 29.51 | 13.60 | 23 | 322135 | 17952 | 70588334 |
Tooth disorder | 29.43 | 13.60 | 198 | 321960 | 23740 | 70582546 |
Colitis microscopic | 29.42 | 13.60 | 99 | 322059 | 8906 | 70597380 |
Soft tissue disorder | 29.34 | 13.60 | 54 | 322104 | 3320 | 70602966 |
Escherichia infection | 29.30 | 13.60 | 19 | 322139 | 16312 | 70589974 |
Memory impairment | 29.27 | 13.60 | 274 | 321884 | 92367 | 70513919 |
Central nervous system lesion | 29.24 | 13.60 | 10 | 322148 | 12443 | 70593843 |
Tardive dyskinesia | 29.10 | 13.60 | 5 | 322153 | 9924 | 70596362 |
Posterior reversible encephalopathy syndrome | 29.07 | 13.60 | 41 | 322117 | 24361 | 70581925 |
Ileus paralytic | 29.04 | 13.60 | 3 | 322155 | 8758 | 70597528 |
Apathy | 28.95 | 13.60 | 9 | 322149 | 11899 | 70594387 |
Dysphonia | 28.90 | 13.60 | 123 | 322035 | 49977 | 70556309 |
Throat tightness | 28.87 | 13.60 | 43 | 322115 | 24979 | 70581307 |
Bundle branch block left | 28.86 | 13.60 | 6 | 322152 | 10393 | 70595893 |
Spinal fusion surgery | 28.70 | 13.60 | 59 | 322099 | 3938 | 70602348 |
Asphyxia | 28.63 | 13.60 | 6 | 322152 | 10336 | 70595950 |
Epistaxis | 28.51 | 13.60 | 313 | 321845 | 102314 | 70503972 |
Latent tuberculosis | 28.47 | 13.60 | 51 | 322107 | 3070 | 70603216 |
Hyperammonaemia | 28.44 | 13.60 | 6 | 322152 | 10287 | 70595999 |
Bladder cancer | 28.39 | 13.60 | 22 | 322136 | 17220 | 70589066 |
Osteomyelitis | 28.32 | 13.60 | 235 | 321923 | 30083 | 70576203 |
Arthritis bacterial | 28.22 | 13.60 | 92 | 322066 | 8141 | 70598145 |
Enterocolitis | 28.17 | 13.60 | 12 | 322146 | 13054 | 70593232 |
Deep vein thrombosis postoperative | 28.00 | 13.60 | 55 | 322103 | 3552 | 70602734 |
Feeling abnormal | 27.96 | 13.60 | 466 | 321692 | 141853 | 70464433 |
Pneumonia viral | 27.84 | 13.60 | 92 | 322066 | 8200 | 70598086 |
Bedridden | 27.83 | 13.60 | 112 | 322046 | 10986 | 70595300 |
Abnormal dreams | 27.66 | 13.60 | 7 | 322151 | 10596 | 70595690 |
Bunion operation | 27.53 | 13.60 | 26 | 322132 | 821 | 70605465 |
Rash macular | 27.47 | 13.60 | 46 | 322112 | 25498 | 70580788 |
Enteritis | 27.32 | 13.60 | 12 | 322146 | 12819 | 70593467 |
Proteinuria | 27.11 | 13.60 | 58 | 322100 | 29316 | 70576970 |
Cerebral ischaemia | 26.92 | 13.60 | 7 | 322151 | 10405 | 70595881 |
Respiratory disorder | 26.88 | 13.60 | 284 | 321874 | 38839 | 70567447 |
Eye swelling | 26.84 | 13.60 | 41 | 322117 | 23573 | 70582713 |
Neck mass | 26.83 | 13.60 | 59 | 322099 | 4127 | 70602159 |
Frequent bowel movements | 26.76 | 13.60 | 34 | 322124 | 21119 | 70585167 |
Blindness | 26.71 | 13.60 | 40 | 322118 | 23187 | 70583099 |
Hospice care | 26.71 | 13.60 | 3 | 322155 | 8202 | 70598084 |
Hepatitis cholestatic | 26.67 | 13.60 | 12 | 322146 | 12638 | 70593648 |
Hypersomnia | 26.66 | 13.60 | 33 | 322125 | 20731 | 70585555 |
Hyperlipidaemia | 26.58 | 13.60 | 42 | 322116 | 23821 | 70582465 |
Soft tissue swelling | 26.54 | 13.60 | 30 | 322128 | 1174 | 70605112 |
Drug level below therapeutic | 26.45 | 13.60 | 4 | 322154 | 8719 | 70597567 |
Disease susceptibility | 26.41 | 13.60 | 17 | 322141 | 300 | 70605986 |
Glycosylated haemoglobin increased | 26.40 | 13.60 | 24 | 322134 | 17367 | 70588919 |
Productive cough | 26.36 | 13.60 | 228 | 321930 | 78109 | 70528177 |
Lip dry | 26.36 | 13.60 | 101 | 322057 | 9684 | 70596602 |
Thirst | 26.34 | 13.60 | 17 | 322141 | 14632 | 70591654 |
Eructation | 26.33 | 13.60 | 6 | 322152 | 9754 | 70596532 |
Psychomotor hyperactivity | 26.30 | 13.60 | 19 | 322139 | 15414 | 70590872 |
Gait disturbance | 26.23 | 13.60 | 1059 | 321099 | 184047 | 70422239 |
Cystitis haemorrhagic | 25.92 | 13.60 | 4 | 322154 | 8589 | 70597697 |
Haematocrit decreased | 25.92 | 13.60 | 153 | 322005 | 57105 | 70549181 |
Breast cancer metastatic | 25.89 | 13.60 | 7 | 322151 | 10139 | 70596147 |
Middle lobe syndrome | 25.88 | 13.60 | 9 | 322149 | 33 | 70606253 |
Premature labour | 25.86 | 13.60 | 3 | 322155 | 7997 | 70598289 |
Pulseless electrical activity | 25.65 | 13.60 | 14 | 322144 | 13201 | 70593085 |
Retching | 25.54 | 13.60 | 21 | 322137 | 15958 | 70590328 |
Immobile | 25.43 | 13.60 | 76 | 322082 | 6418 | 70599868 |
Hyperuricaemia | 25.41 | 13.60 | 9 | 322149 | 10957 | 70595329 |
Abscess | 25.31 | 13.60 | 34 | 322124 | 20620 | 70585666 |
Benign prostatic hyperplasia | 25.20 | 13.60 | 8 | 322150 | 10435 | 70595851 |
Petechiae | 25.12 | 13.60 | 30 | 322128 | 19142 | 70587144 |
Personality change | 24.86 | 13.60 | 5 | 322153 | 8865 | 70597421 |
Pseudomonas infection | 24.59 | 13.60 | 30 | 322128 | 18964 | 70587322 |
Device leakage | 24.56 | 13.60 | 6 | 322152 | 9302 | 70596984 |
Cardiac failure chronic | 24.54 | 13.60 | 8 | 322150 | 10261 | 70596025 |
Exercise tolerance decreased | 24.52 | 13.60 | 4 | 322154 | 8244 | 70598042 |
Hepatomegaly | 24.41 | 13.60 | 26 | 322132 | 17466 | 70588820 |
Bacterial sepsis | 24.39 | 13.60 | 3 | 322155 | 7644 | 70598642 |
Cholangitis | 24.28 | 13.60 | 11 | 322147 | 11538 | 70594748 |
Hepatitis C | 24.23 | 13.60 | 14 | 322144 | 12793 | 70593493 |
Brain natriuretic peptide increased | 24.20 | 13.60 | 4 | 322154 | 8167 | 70598119 |
Tendon disorder | 24.10 | 13.60 | 75 | 322083 | 6476 | 70599810 |
Peritonitis bacterial | 24.08 | 13.60 | 6 | 322152 | 9178 | 70597108 |
Live birth | 24.07 | 13.60 | 125 | 322033 | 13654 | 70592632 |
Osteonecrosis of jaw | 24.06 | 13.60 | 100 | 322058 | 40902 | 70565384 |
Renal disorder | 24.02 | 13.60 | 90 | 322068 | 37919 | 70568367 |
Swelling face | 23.95 | 13.60 | 178 | 321980 | 62986 | 70543300 |
Abdominal pain upper | 23.71 | 13.60 | 1091 | 321067 | 192511 | 70413775 |
Hypertriglyceridaemia | 23.68 | 13.60 | 12 | 322146 | 11799 | 70594487 |
Vascular device infection | 23.63 | 13.60 | 4 | 322154 | 8026 | 70598260 |
Glomerular filtration rate decreased | 23.62 | 13.60 | 36 | 322122 | 20720 | 70585566 |
Acute hepatic failure | 23.62 | 13.60 | 57 | 322101 | 27615 | 70578671 |
Hypothyroidism | 23.62 | 13.60 | 117 | 322041 | 45638 | 70560648 |
Laryngitis | 23.35 | 13.60 | 123 | 322035 | 13508 | 70592778 |
Gout | 23.32 | 13.60 | 43 | 322115 | 22963 | 70583323 |
Myositis | 23.30 | 13.60 | 27 | 322131 | 17462 | 70588824 |
Prostatic specific antigen increased | 23.29 | 13.60 | 7 | 322151 | 9459 | 70596827 |
Hypovolaemic shock | 23.29 | 13.60 | 10 | 322148 | 10827 | 70595459 |
COVID-19 pneumonia | 23.22 | 13.60 | 40 | 322118 | 21929 | 70584357 |
Nephropathy toxic | 23.17 | 13.60 | 30 | 322128 | 18484 | 70587802 |
Abortion spontaneous | 23.04 | 13.60 | 54 | 322104 | 26425 | 70579861 |
Smear cervix abnormal | 22.95 | 13.60 | 40 | 322118 | 2356 | 70603930 |
Nystagmus | 22.87 | 13.60 | 7 | 322151 | 9348 | 70596938 |
Haemolysis | 22.77 | 13.60 | 12 | 322146 | 11539 | 70594747 |
Oedema | 22.76 | 13.60 | 332 | 321826 | 103249 | 70503037 |
Blood albumin decreased | 22.75 | 13.60 | 41 | 322117 | 22086 | 70584200 |
Hypercapnia | 22.71 | 13.60 | 5 | 322153 | 8324 | 70597962 |
Unevaluable event | 22.58 | 13.60 | 141 | 322017 | 51922 | 70554364 |
Pyelonephritis | 22.52 | 13.60 | 30 | 322128 | 18259 | 70588027 |
Azotaemia | 22.52 | 13.60 | 4 | 322154 | 7749 | 70598537 |
Increased appetite | 22.48 | 13.60 | 10 | 322148 | 10603 | 70595683 |
Overwork | 22.46 | 13.60 | 9 | 322149 | 53 | 70606233 |
Carotid artery stenosis | 22.35 | 13.60 | 5 | 322153 | 8231 | 70598055 |
Haemolytic anaemia | 22.30 | 13.60 | 26 | 322132 | 16768 | 70589518 |
Spinal disorder | 22.29 | 13.60 | 92 | 322066 | 9128 | 70597158 |
Peripheral venous disease | 22.29 | 13.60 | 102 | 322056 | 10585 | 70595701 |
Thrombotic microangiopathy | 22.26 | 13.60 | 29 | 322129 | 17819 | 70588467 |
Congestive cardiomyopathy | 22.06 | 13.60 | 11 | 322147 | 10915 | 70595371 |
Diabetic eye disease | 22.03 | 13.60 | 12 | 322146 | 153 | 70606133 |
Lipase increased | 22.03 | 13.60 | 22 | 322136 | 15224 | 70591062 |
Walking aid user | 22.01 | 13.60 | 83 | 322075 | 7898 | 70598388 |
Blood potassium increased | 22.00 | 13.60 | 58 | 322100 | 27268 | 70579018 |
Muscle spasms | 21.97 | 13.60 | 532 | 321626 | 153514 | 70452772 |
Tender joint count increased | 21.96 | 13.60 | 12 | 322146 | 154 | 70606132 |
Staphylococcal infection | 21.96 | 13.60 | 147 | 322011 | 53257 | 70553029 |
Peripheral sensory neuropathy | 21.85 | 13.60 | 14 | 322144 | 12096 | 70594190 |
Oropharyngeal pain | 21.76 | 13.60 | 307 | 321851 | 96003 | 70510283 |
Cerebral atrophy | 21.69 | 13.60 | 4 | 322154 | 7543 | 70598743 |
Neck surgery | 21.68 | 13.60 | 32 | 322126 | 1636 | 70604650 |
Nail psoriasis | 21.63 | 13.60 | 18 | 322140 | 479 | 70605807 |
Musculoskeletal discomfort | 21.62 | 13.60 | 147 | 322011 | 17685 | 70588601 |
Respiratory tract infection | 21.55 | 13.60 | 109 | 322049 | 42289 | 70563997 |
Coronary artery occlusion | 21.54 | 13.60 | 20 | 322138 | 14325 | 70591961 |
Skin reaction | 21.54 | 13.60 | 123 | 322035 | 13926 | 70592360 |
Caesarean section | 21.52 | 13.60 | 13 | 322145 | 11594 | 70594692 |
Large intestine perforation | 21.52 | 13.60 | 17 | 322141 | 13178 | 70593108 |
Erythema | 21.39 | 13.60 | 717 | 321441 | 198846 | 70407440 |
Neurological symptom | 21.39 | 13.60 | 4 | 322154 | 7469 | 70598817 |
Therapeutic response unexpected | 21.35 | 13.60 | 31 | 322127 | 18200 | 70588086 |
Refusal of treatment by patient | 21.32 | 13.60 | 6 | 322152 | 8464 | 70597822 |
Rash papular | 21.29 | 13.60 | 31 | 322127 | 18179 | 70588107 |
Eyelid oedema | 21.26 | 13.60 | 16 | 322142 | 12711 | 70593575 |
Viral upper respiratory tract infection | 21.26 | 13.60 | 86 | 322072 | 8456 | 70597830 |
Muscle relaxant therapy | 21.24 | 13.60 | 12 | 322146 | 165 | 70606121 |
Progressive multifocal leukoencephalopathy | 21.23 | 13.60 | 34 | 322124 | 19180 | 70587106 |
Nervous system disorder | 21.20 | 13.60 | 49 | 322109 | 24097 | 70582189 |
Blood culture positive | 21.13 | 13.60 | 5 | 322153 | 7921 | 70598365 |
Gastric haemorrhage | 21.04 | 13.60 | 20 | 322138 | 14165 | 70592121 |
Cerebral haematoma | 21.01 | 13.60 | 4 | 322154 | 7374 | 70598912 |
Urticarial vasculitis | 21.01 | 13.60 | 19 | 322139 | 567 | 70605719 |
Mean cell haemoglobin decreased | 20.96 | 13.60 | 62 | 322096 | 5206 | 70601080 |
Cold sweat | 20.86 | 13.60 | 28 | 322130 | 16988 | 70589298 |
Spinal meningioma benign | 20.82 | 13.60 | 10 | 322148 | 96 | 70606190 |
Swollen tongue | 20.73 | 13.60 | 92 | 322066 | 36954 | 70569332 |
Loss of employment | 20.72 | 13.60 | 37 | 322121 | 2222 | 70604064 |
Muscle tightness | 20.68 | 13.60 | 14 | 322144 | 11748 | 70594538 |
Blood pressure systolic decreased | 20.66 | 13.60 | 9 | 322149 | 9662 | 70596624 |
Extra dose administered | 20.61 | 13.60 | 4 | 322154 | 7273 | 70599013 |
Erythema multiforme | 20.57 | 13.60 | 27 | 322131 | 16537 | 70589749 |
Pleural thickening | 20.56 | 13.60 | 42 | 322116 | 2790 | 70603496 |
Duodenal ulcer haemorrhage | 20.56 | 13.60 | 3 | 322155 | 6715 | 70599571 |
Knee deformity | 20.53 | 13.60 | 24 | 322134 | 974 | 70605312 |
Left ventricular failure | 20.51 | 13.60 | 7 | 322151 | 8721 | 70597565 |
Prescribed overdose | 20.44 | 13.60 | 201 | 321957 | 26980 | 70579306 |
Hepatitis acute | 20.34 | 13.60 | 20 | 322138 | 13942 | 70592344 |
Thinking abnormal | 20.32 | 13.60 | 15 | 322143 | 12036 | 70594250 |
Neoplasm malignant | 20.30 | 13.60 | 210 | 321948 | 28564 | 70577722 |
Colon cancer | 20.26 | 13.60 | 21 | 322137 | 14285 | 70592001 |
Tender joint count | 20.25 | 13.60 | 9 | 322149 | 71 | 70606215 |
Coeliac disease | 20.18 | 13.60 | 88 | 322070 | 8945 | 70597341 |
Sinus node dysfunction | 20.18 | 13.60 | 4 | 322154 | 7165 | 70599121 |
Potentiating drug interaction | 20.15 | 13.60 | 6 | 322152 | 8158 | 70598128 |
Tenderness | 20.13 | 13.60 | 165 | 321993 | 21045 | 70585241 |
Cardiac tamponade | 20.01 | 13.60 | 7 | 322151 | 8588 | 70597698 |
Mean cell haemoglobin concentration abnormal | 20.01 | 13.60 | 11 | 322147 | 143 | 70606143 |
Restless legs syndrome | 19.99 | 13.60 | 33 | 322125 | 18395 | 70587891 |
Device malfunction | 19.94 | 13.60 | 35 | 322123 | 19049 | 70587237 |
Major depression | 19.93 | 13.60 | 7 | 322151 | 8567 | 70597719 |
Hepatic ischaemia | 19.75 | 13.60 | 24 | 322134 | 1015 | 70605271 |
Hepatic cirrhosis | 19.69 | 13.60 | 220 | 321938 | 30511 | 70575775 |
Metabolic disorder | 19.68 | 13.60 | 6 | 322152 | 8034 | 70598252 |
Hypertonia | 19.66 | 13.60 | 3 | 322155 | 6495 | 70599791 |
Dermatitis acneiform | 19.63 | 13.60 | 8 | 322150 | 8937 | 70597349 |
Enthesophyte | 19.54 | 13.60 | 6 | 322152 | 13 | 70606273 |
Sensory loss | 19.53 | 13.60 | 14 | 322144 | 11405 | 70594881 |
Intervertebral disc compression | 19.50 | 13.60 | 24 | 322134 | 1029 | 70605257 |
Aortic valve incompetence | 19.48 | 13.60 | 8 | 322150 | 8896 | 70597390 |
Drug specific antibody present | 19.43 | 13.60 | 64 | 322094 | 5694 | 70600592 |
Brain herniation | 19.33 | 13.60 | 4 | 322154 | 6952 | 70599334 |
Feeling cold | 19.30 | 13.60 | 56 | 322102 | 25514 | 70580772 |
Transplant rejection | 19.29 | 13.60 | 33 | 322125 | 18138 | 70588148 |
Paralysis | 19.13 | 13.60 | 16 | 322142 | 12056 | 70594230 |
Injection site pain | 19.10 | 13.60 | 398 | 321760 | 117221 | 70489065 |
Aortic arteriosclerosis | 19.04 | 13.60 | 6 | 322152 | 7863 | 70598423 |
Presbyacusis | 19.02 | 13.60 | 39 | 322119 | 2598 | 70603688 |
Feeling hot | 19.01 | 13.60 | 136 | 322022 | 48534 | 70557752 |
Extrasystoles | 19.00 | 13.60 | 4 | 322154 | 6870 | 70599416 |
Aplasia pure red cell | 18.99 | 13.60 | 5 | 322153 | 7369 | 70598917 |
Lung consolidation | 18.94 | 13.60 | 7 | 322151 | 8299 | 70597987 |
Jaundice cholestatic | 18.91 | 13.60 | 9 | 322149 | 9175 | 70597111 |
Alanine aminotransferase increased | 18.91 | 13.60 | 835 | 321323 | 146645 | 70459641 |
Lung infiltration | 18.89 | 13.60 | 44 | 322114 | 21580 | 70584706 |
Ventricular arrhythmia | 18.89 | 13.60 | 6 | 322152 | 7824 | 70598462 |
Normal newborn | 18.85 | 13.60 | 3 | 322155 | 6297 | 70599989 |
Decubitus ulcer | 18.81 | 13.60 | 22 | 322136 | 14169 | 70592117 |
Forced expiratory volume decreased | 18.75 | 13.60 | 5 | 322153 | 7309 | 70598977 |
Arthritis infective | 18.74 | 13.60 | 75 | 322083 | 7337 | 70598949 |
Pulmonary function test decreased | 18.72 | 13.60 | 4 | 322154 | 6797 | 70599489 |
Allergy to chemicals | 18.70 | 13.60 | 33 | 322125 | 1963 | 70604323 |
Pleural fibrosis | 18.70 | 13.60 | 51 | 322107 | 4088 | 70602198 |
Peripheral coldness | 18.67 | 13.60 | 23 | 322135 | 14477 | 70591809 |
Embolic stroke | 18.66 | 13.60 | 5 | 322153 | 7284 | 70599002 |
Wheezing | 18.61 | 13.60 | 308 | 321850 | 93862 | 70512424 |
Bacterial infection | 18.58 | 13.60 | 60 | 322098 | 26432 | 70579854 |
Ocular hyperaemia | 18.57 | 13.60 | 54 | 322104 | 24585 | 70581701 |
Neuralgia | 18.56 | 13.60 | 67 | 322091 | 28536 | 70577750 |
Hepatic necrosis | 18.54 | 13.60 | 8 | 322150 | 8638 | 70597648 |
Hiatus hernia | 18.46 | 13.60 | 43 | 322115 | 21091 | 70585195 |
Oral disorder | 18.45 | 13.60 | 87 | 322071 | 9142 | 70597144 |
Inflammatory pain | 18.44 | 13.60 | 22 | 322136 | 913 | 70605373 |
Supraventricular extrasystoles | 18.44 | 13.60 | 3 | 322155 | 6195 | 70600091 |
Urosepsis | 18.40 | 13.60 | 52 | 322106 | 23897 | 70582389 |
Facial paralysis | 18.37 | 13.60 | 39 | 322119 | 19769 | 70586517 |
Therapy change | 18.35 | 13.60 | 4 | 322154 | 6705 | 70599581 |
Generalised oedema | 18.31 | 13.60 | 45 | 322113 | 21663 | 70584623 |
Limb operation | 18.24 | 13.60 | 42 | 322116 | 3030 | 70603256 |
Amylase increased | 18.15 | 13.60 | 12 | 322146 | 10196 | 70596090 |
Hydrocephalus | 18.12 | 13.60 | 7 | 322151 | 8078 | 70598208 |
Metastasis | 18.10 | 13.60 | 3 | 322155 | 6111 | 70600175 |
Renal tubular disorder | 18.08 | 13.60 | 3 | 322155 | 6107 | 70600179 |
Ammonia increased | 18.08 | 13.60 | 5 | 322153 | 7133 | 70599153 |
Hypertransaminasaemia | 18.06 | 13.60 | 9 | 322149 | 8934 | 70597352 |
Pyopneumothorax | 18.01 | 13.60 | 8 | 322150 | 63 | 70606223 |
Pregnancy | 17.95 | 13.60 | 176 | 321982 | 23605 | 70582681 |
Intestinal ischaemia | 17.90 | 13.60 | 17 | 322141 | 12047 | 70594239 |
Thrombosis | 17.88 | 13.60 | 238 | 321920 | 75167 | 70531119 |
Ventricular hypertrophy | 17.86 | 13.60 | 4 | 322154 | 6580 | 70599706 |
Eyelid ptosis | 17.79 | 13.60 | 12 | 322146 | 10090 | 70596196 |
Heart rate irregular | 17.79 | 13.60 | 72 | 322086 | 29671 | 70576615 |
Eye disorder | 17.78 | 13.60 | 158 | 322000 | 20627 | 70585659 |
Post procedural complication | 17.67 | 13.60 | 47 | 322111 | 22034 | 70584252 |
Wheelchair user | 17.64 | 13.60 | 58 | 322100 | 5156 | 70601130 |
Squamous cell carcinoma of skin | 17.62 | 13.60 | 19 | 322139 | 12693 | 70593593 |
Dry eye | 17.56 | 13.60 | 224 | 321934 | 32058 | 70574228 |
Oral discomfort | 17.47 | 13.60 | 83 | 322075 | 8748 | 70597538 |
Immunosuppressant drug level increased | 17.47 | 13.60 | 7 | 322151 | 7900 | 70598386 |
Blood lactic acid increased | 17.47 | 13.60 | 15 | 322143 | 11158 | 70595128 |
Eye movement disorder | 17.42 | 13.60 | 6 | 322152 | 7434 | 70598852 |
Rib fracture | 17.39 | 13.60 | 58 | 322100 | 25298 | 70580988 |
Pulmonary alveolar haemorrhage | 17.36 | 13.60 | 13 | 322145 | 10356 | 70595930 |
Steatohepatitis | 17.36 | 13.60 | 20 | 322138 | 799 | 70605487 |
Spinal cord compression | 17.34 | 13.60 | 3 | 322155 | 5925 | 70600361 |
Amenorrhoea | 17.28 | 13.60 | 5 | 322153 | 6925 | 70599361 |
Dermatitis exfoliative generalised | 17.19 | 13.60 | 4 | 322154 | 6410 | 70599876 |
Multiple-drug resistance | 17.11 | 13.60 | 6 | 322152 | 7349 | 70598937 |
Arteriosclerosis | 16.95 | 13.60 | 31 | 322127 | 16607 | 70589679 |
Concomitant disease aggravated | 16.91 | 13.60 | 18 | 322140 | 12096 | 70594190 |
Hepatitis | 16.89 | 13.60 | 320 | 321838 | 49660 | 70556626 |
Diarrhoea haemorrhagic | 16.86 | 13.60 | 17 | 322141 | 11713 | 70594573 |
Inflammatory marker increased | 16.80 | 13.60 | 85 | 322073 | 9189 | 70597097 |
Retinal haemorrhage | 16.75 | 13.60 | 7 | 322151 | 7703 | 70598583 |
Odynophagia | 16.73 | 13.60 | 13 | 322145 | 10162 | 70596124 |
Mycobacterium marinum infection | 16.71 | 13.60 | 15 | 322143 | 443 | 70605843 |
Cataract | 16.71 | 13.60 | 350 | 321808 | 55295 | 70550991 |
Ageusia | 16.70 | 13.60 | 26 | 322132 | 14836 | 70591450 |
Viral infection | 16.63 | 13.60 | 104 | 322054 | 38287 | 70567999 |
General physical health deterioration | 16.63 | 13.60 | 1266 | 320892 | 234765 | 70371521 |
Flank pain | 16.62 | 13.60 | 34 | 322124 | 17468 | 70588818 |
Food allergy | 16.59 | 13.60 | 9 | 322149 | 8515 | 70597771 |
Tongue oedema | 16.59 | 13.60 | 4 | 322154 | 6255 | 70600031 |
Gastric ulcer haemorrhage | 16.57 | 13.60 | 9 | 322149 | 8509 | 70597777 |
Back disorder | 16.53 | 13.60 | 93 | 322065 | 10471 | 70595815 |
Mood altered | 16.52 | 13.60 | 31 | 322127 | 16444 | 70589842 |
Hyperventilation | 16.48 | 13.60 | 6 | 322152 | 7180 | 70599106 |
Hepatic steatosis | 16.48 | 13.60 | 230 | 321928 | 33583 | 70572703 |
Gastritis erosive | 16.47 | 13.60 | 13 | 322145 | 10082 | 70596204 |
Vitreous floaters | 16.42 | 13.60 | 5 | 322153 | 6699 | 70599587 |
Hepatic fibrosis | 16.32 | 13.60 | 64 | 322094 | 6203 | 70600083 |
Feeding disorder | 16.25 | 13.60 | 117 | 322041 | 14339 | 70591947 |
Interstitial lung disease | 16.25 | 13.60 | 605 | 321553 | 104080 | 70502206 |
Joint noise | 16.23 | 13.60 | 43 | 322115 | 3388 | 70602898 |
Malignant neoplasm of conjunctiva | 16.22 | 13.60 | 7 | 322151 | 51 | 70606235 |
Elbow deformity | 16.18 | 13.60 | 26 | 322132 | 1432 | 70604854 |
Urine analysis abnormal | 16.18 | 13.60 | 4 | 322154 | 6150 | 70600136 |
Cartilage atrophy | 16.17 | 13.60 | 10 | 322148 | 164 | 70606122 |
Swollen joint count | 16.15 | 13.60 | 21 | 322137 | 952 | 70605334 |
Pneumonia bacterial | 16.08 | 13.60 | 32 | 322126 | 16609 | 70589677 |
Stress at work | 16.03 | 13.60 | 22 | 322136 | 1051 | 70605235 |
Pharyngeal oedema | 15.93 | 13.60 | 124 | 322034 | 15572 | 70590714 |
Hip fracture | 15.93 | 13.60 | 70 | 322088 | 28193 | 70578093 |
Blood phosphorus decreased | 15.85 | 13.60 | 4 | 322154 | 6065 | 70600221 |
Nervousness | 15.82 | 13.60 | 80 | 322078 | 31040 | 70575246 |
Pneumothorax | 15.82 | 13.60 | 62 | 322096 | 25784 | 70580502 |
Pseudomonal sepsis | 15.77 | 13.60 | 3 | 322155 | 5534 | 70600752 |
Thyroid disorder | 15.69 | 13.60 | 106 | 322052 | 12726 | 70593560 |
Haemorrhoidal haemorrhage | 15.65 | 13.60 | 4 | 322154 | 6015 | 70600271 |
CD4/CD8 ratio increased | 15.65 | 13.60 | 5 | 322153 | 13 | 70606273 |
Device occlusion | 15.64 | 13.60 | 15 | 322143 | 10580 | 70595706 |
Blood triglycerides increased | 15.63 | 13.60 | 42 | 322116 | 19622 | 70586664 |
Portal hypertension | 15.62 | 13.60 | 5 | 322153 | 6487 | 70599799 |
Tooth infection | 15.59 | 13.60 | 128 | 322030 | 16335 | 70589951 |
Left ventricular hypertrophy | 15.58 | 13.60 | 14 | 322144 | 10188 | 70596098 |
Gestational diabetes | 15.58 | 13.60 | 4 | 322154 | 5997 | 70600289 |
Dermatitis exfoliative | 15.50 | 13.60 | 15 | 322143 | 10536 | 70595750 |
Cholecystitis acute | 15.47 | 13.60 | 19 | 322139 | 11975 | 70594311 |
Ossicle disorder | 15.46 | 13.60 | 6 | 322152 | 32 | 70606254 |
Serum ferritin increased | 15.46 | 13.60 | 11 | 322147 | 8994 | 70597292 |
Rheumatic disorder | 15.42 | 13.60 | 34 | 322124 | 2382 | 70603904 |
Petit mal epilepsy | 15.40 | 13.60 | 3 | 322155 | 5441 | 70600845 |
Vaginal haematoma | 15.37 | 13.60 | 9 | 322149 | 133 | 70606153 |
Graft versus host disease in gastrointestinal tract | 15.36 | 13.60 | 4 | 322154 | 5940 | 70600346 |
Pain in jaw | 15.35 | 13.60 | 122 | 322036 | 42547 | 70563739 |
Incoherent | 15.29 | 13.60 | 7 | 322151 | 7299 | 70598987 |
Hyperpyrexia | 15.12 | 13.60 | 3 | 322155 | 5371 | 70600915 |
Non-small cell lung cancer | 15.07 | 13.60 | 5 | 322153 | 6342 | 70599944 |
Pancreatic carcinoma | 15.06 | 13.60 | 22 | 322136 | 12882 | 70593404 |
Large intestine polyp | 14.99 | 13.60 | 18 | 322140 | 11458 | 70594828 |
Product monitoring error | 14.97 | 13.60 | 6 | 322152 | 6770 | 70599516 |
Bowel movement irregularity | 14.95 | 13.60 | 3 | 322155 | 5329 | 70600957 |
Choking | 14.82 | 13.60 | 17 | 322141 | 11043 | 70595243 |
Dry throat | 14.79 | 13.60 | 6 | 322152 | 6722 | 70599564 |
Splenic embolism | 14.72 | 13.60 | 10 | 322148 | 194 | 70606092 |
Glaucoma | 14.70 | 13.60 | 136 | 322022 | 17956 | 70588330 |
Hot flush | 14.67 | 13.60 | 149 | 322009 | 49435 | 70556851 |
Sebaceous gland infection | 14.64 | 13.60 | 9 | 322149 | 146 | 70606140 |
Pulmonary granuloma | 14.63 | 13.60 | 29 | 322129 | 1885 | 70604401 |
Aspartate aminotransferase increased | 14.57 | 13.60 | 711 | 321447 | 126267 | 70480019 |
Haemorrhagic stroke | 14.54 | 13.60 | 15 | 322143 | 10227 | 70596059 |
Device related sepsis | 14.53 | 13.60 | 4 | 322154 | 5724 | 70600562 |
Peripheral arterial occlusive disease | 14.51 | 13.60 | 8 | 322150 | 7501 | 70598785 |
Splenomegaly | 14.48 | 13.60 | 41 | 322117 | 18829 | 70587457 |
Gangrene | 14.46 | 13.60 | 10 | 322148 | 8299 | 70597987 |
Thrombotic thrombocytopenic purpura | 14.43 | 13.60 | 5 | 322153 | 6172 | 70600114 |
Liver disorder | 14.39 | 13.60 | 374 | 321784 | 61194 | 70545092 |
Cardiac granuloma | 14.38 | 13.60 | 4 | 322154 | 5 | 70606281 |
Nail operation | 14.36 | 13.60 | 15 | 322143 | 536 | 70605750 |
Gastrointestinal perforation | 14.35 | 13.60 | 4 | 322154 | 5677 | 70600609 |
Aortic aneurysm | 14.34 | 13.60 | 9 | 322149 | 7864 | 70598422 |
Orthopnoea | 14.26 | 13.60 | 13 | 322145 | 9395 | 70596891 |
Onychomadesis | 14.21 | 13.60 | 46 | 322112 | 4055 | 70602231 |
Dermatitis contact | 14.16 | 13.60 | 14 | 322144 | 9735 | 70596551 |
Oral surgery | 14.14 | 13.60 | 20 | 322138 | 983 | 70605303 |
Gastrointestinal necrosis | 14.10 | 13.60 | 3 | 322155 | 5115 | 70601171 |
Functional gastrointestinal disorder | 14.09 | 13.60 | 49 | 322109 | 4482 | 70601804 |
Pseudomembranous colitis | 14.08 | 13.60 | 3 | 322155 | 5108 | 70601178 |
Haemophagocytic lymphohistiocytosis | 14.05 | 13.60 | 44 | 322114 | 19568 | 70586718 |
Accident | 14.04 | 13.60 | 68 | 322090 | 7223 | 70599063 |
Blood magnesium increased | 14.02 | 13.60 | 40 | 322118 | 3291 | 70602995 |
Polyneuropathy | 14.00 | 13.60 | 50 | 322108 | 21365 | 70584921 |
Adenovirus infection | 13.99 | 13.60 | 9 | 322149 | 7759 | 70598527 |
Product label confusion | 13.98 | 13.60 | 18 | 322140 | 808 | 70605478 |
Anal fistula | 13.96 | 13.60 | 5 | 322153 | 6045 | 70600241 |
Lacrimal disorder | 13.95 | 13.60 | 14 | 322144 | 477 | 70605809 |
Aortic bruit | 13.91 | 13.60 | 10 | 322148 | 213 | 70606073 |
Drug level above therapeutic | 13.90 | 13.60 | 9 | 322149 | 7733 | 70598553 |
Cell-mediated cytotoxicity | 13.87 | 13.60 | 6 | 322152 | 44 | 70606242 |
Systemic inflammatory response syndrome | 13.78 | 13.60 | 17 | 322141 | 10695 | 70595591 |
Cytopenia | 13.77 | 13.60 | 37 | 322121 | 17286 | 70589000 |
Leukoencephalopathy | 13.76 | 13.60 | 8 | 322150 | 7286 | 70599000 |
Metastases to lymph nodes | 13.73 | 13.60 | 13 | 322145 | 9225 | 70597061 |
Pyelonephritis acute | 13.72 | 13.60 | 4 | 322154 | 5513 | 70600773 |
Rotator cuff syndrome | 13.71 | 13.60 | 102 | 322056 | 12632 | 70593654 |
Taste disorder | 13.69 | 13.60 | 19 | 322139 | 11366 | 70594920 |
Rebound effect | 13.67 | 13.60 | 5 | 322153 | 5966 | 70600320 |
Expired product administered | 13.65 | 13.60 | 6 | 322152 | 6407 | 70599879 |
Diffuse idiopathic skeletal hyperostosis | 13.65 | 13.60 | 6 | 322152 | 46 | 70606240 |
None
Source | Code | Description |
---|---|---|
ATC | L04AA13 | ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS IMMUNOSUPPRESSANTS IMMUNOSUPPRESSANTS Selective immunosuppressants |
MeSH PA | D000700 | Analgesics |
MeSH PA | D018712 | Analgesics, Non-Narcotic |
MeSH PA | D000893 | Anti-Inflammatory Agents |
MeSH PA | D000894 | Anti-Inflammatory Agents, Non-Steroidal |
MeSH PA | D018501 | Antirheumatic Agents |
MeSH PA | D007155 | Immunologic Factors |
MeSH PA | D007166 | Immunosuppressive Agents |
MeSH PA | D018373 | Peripheral Nervous System Agents |
MeSH PA | D018689 | Sensory System Agents |
MeSH PA | D004791 | Enzyme Inhibitors |
CHEBI has role | CHEBI:35442 | antiparasitic drugs |
CHEBI has role | CHEBI:35475 | non-steroidal anti-inflammatory agent |
CHEBI has role | CHEBI:35610 | antineoplastic agents |
CHEBI has role | CHEBI:35705 | immunosuppressive agents |
CHEBI has role | CHEBI:37153 | protein serine/threonine phosphatase inhibitors |
CHEBI has role | CHEBI:38637 | tyrosine kinase inhibitors |
CHEBI has role | CHEBI:50266 | Prodrugs |
CHEBI has role | CHEBI:50908 | agente hepatotoxico |
CHEBI has role | CHEBI:68542 | DHODH inhibitor |
CHEBI has role | CHEBI:68543 | pyrimidine synthesis inhibitors |
FDA EPC | N0000175713 | Antirheumatic Agent |
FDA MoA | N0000185501 | Dihydroorotate Dehydrogenase Inhibitors |
FDA EPC | N0000185502 | Pyrimidine Synthesis Inhibitor |
CHEBI has role | CHEBI:49103 | drug metabolites |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Psoriasis with arthropathy | indication | 33339001 | |
Rheumatoid arthritis | indication | 69896004 | DOID:7148 |
Inactive tuberculosis | contraindication | 11999007 | |
Agranulocytosis | contraindication | 17182001 | DOID:12987 |
Acute tuberculosis | contraindication | 25629007 | |
Immunosuppression | contraindication | 38013005 | |
Hepatic failure | contraindication | 59927004 | |
Chronic type B viral hepatitis | contraindication | 61977001 | |
Acute infectious disease | contraindication | 63171007 | |
Interstitial pneumonia | contraindication | 64667001 | |
Aspergillosis | contraindication | 65553006 | DOID:13564 |
Viral hepatitis type B | contraindication | 66071002 | DOID:2043 |
Kidney disease | contraindication | 90708001 | DOID:557 |
Pancytopenia | contraindication | 127034005 | DOID:12450 |
Chronic hepatitis C | contraindication | 128302006 | |
Liver function tests abnormal | contraindication | 166603001 | |
Disease of liver | contraindication | 235856003 | DOID:409 |
Acute hepatitis C | contraindication | 235866006 | |
Anemia | contraindication | 271737000 | DOID:2355 |
Pregnancy, function | contraindication | 289908002 | |
Thrombocytopenic disorder | contraindication | 302215000 | DOID:1588 |
Peripheral nerve disease | contraindication | 302226006 | |
Neutropenic disorder | contraindication | 303011007 | DOID:1227 |
Breastfeeding (mother) | contraindication | 413712001 | |
Pneumocystosis jiroveci pneumonia | contraindication | 415125002 | DOID:11339 |
Severe Bone Marrow Depression | contraindication |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 12.31 | acidic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Dihydroorotate dehydrogenase (quinone), mitochondrial | Enzyme | INHIBITOR | IC50 | 5 | CHEMBL | CHEMBL | |||
Sodium-dependent noradrenaline transporter | Transporter | Ki | 5.34 | DRUG MATRIX | |||||
Sodium-dependent dopamine transporter | Transporter | Ki | 5.64 | DRUG MATRIX | |||||
Cytochrome P450 1A2 | Enzyme | IC50 | 6.30 | DRUG MATRIX | |||||
Amine oxidase [flavin-containing] A | Enzyme | IC50 | 4.68 | DRUG MATRIX | |||||
Sodium/nucleoside cotransporter 1 | Transporter | Ki | 5.29 | DRUG MATRIX | |||||
Dihydroorotate dehydrogenase (quinone), mitochondrial | Enzyme | IC50 | 8.05 | CHEMBL | |||||
Dihydroorotate dehydrogenase (quinone), mitochondrial | Enzyme | IC50 | 7.52 | CHEMBL |
ID | Source |
---|---|
4021132 | VUID |
N0000148586 | NUI |
D00749 | KEGG_DRUG |
4021132 | VANDF |
4031717 | VANDF |
C0063041 | UMLSCUI |
CHEBI:6402 | CHEBI |
CHEBI:68540 | CHEBI |
CHEMBL960 | ChEMBL_ID |
DB01097 | DRUGBANK_ID |
D000077339 | MESH_DESCRIPTOR_UI |
3899 | PUBCHEM_CID |
6825 | IUPHAR_LIGAND_ID |
C527525 | MESH_SUPPLEMENTAL_RECORD_UI |
5079 | INN_ID |
G162GK9U4W | UNII |
1310520 | RXNORM |
11870 | MMSL |
28846 | MMSL |
63949 | MMSL |
7491 | MMSL |
d04349 | MMSL |
d07905 | MMSL |
007642 | NDDF |
014643 | NDDF |
109143003 | SNOMEDCT_US |
386981009 | SNOMEDCT_US |
703785006 | SNOMEDCT_US |
703786007 | SNOMEDCT_US |
C1718383 | UMLSCUI |
DB08880 | DRUGBANK_ID |
7761 | INN_ID |
54684141 | PUBCHEM_CID |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Arava | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0088-2160 | TABLET, FILM COATED | 10 mg | ORAL | NDA | 27 sections |
Arava | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0088-2160 | TABLET, FILM COATED | 10 mg | ORAL | NDA | 27 sections |
Arava | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0088-2161 | TABLET, FILM COATED | 20 mg | ORAL | NDA | 27 sections |
Arava | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0088-2161 | TABLET, FILM COATED | 20 mg | ORAL | NDA | 27 sections |
Arava | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0088-2162 | TABLET, FILM COATED | 100 mg | ORAL | NDA | 27 sections |
Arava | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0088-2162 | TABLET, FILM COATED | 100 mg | ORAL | NDA | 27 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0955-1735 | TABLET, FILM COATED | 10 mg | ORAL | NDA AUTHORIZED GENERIC | 27 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0955-1735 | TABLET, FILM COATED | 10 mg | ORAL | NDA AUTHORIZED GENERIC | 27 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0955-1737 | TABLET, FILM COATED | 20 mg | ORAL | NDA AUTHORIZED GENERIC | 27 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0955-1737 | TABLET, FILM COATED | 20 mg | ORAL | NDA AUTHORIZED GENERIC | 27 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10702-277 | TABLET | 10 mg | ORAL | ANDA | 18 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10702-278 | TABLET | 20 mg | Oral | ANDA | 18 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 23155-043 | TABLET | 10 mg | ORAL | ANDA | 23 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 23155-043 | TABLET | 10 mg | ORAL | ANDA | 23 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 23155-044 | TABLET | 20 mg | ORAL | ANDA | 23 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 23155-044 | TABLET | 20 mg | ORAL | ANDA | 23 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 35573-447 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 27 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 35573-448 | TABLET, FILM COATED | 20 mg | ORAL | ANDA | 27 sections |
LEFLUNOMIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42291-420 | TABLET | 10 mg | ORAL | ANDA | 18 sections |
LEFLUNOMIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42291-421 | TABLET | 20 mg | ORAL | ANDA | 18 sections |
Leflunomide | Human Prescription Drug Label | 1 | 46708-436 | TABLET | 10 mg | ORAL | ANDA | 26 sections |
Leflunomide | Human Prescription Drug Label | 1 | 46708-437 | TABLET | 20 mg | ORAL | ANDA | 26 sections |
Leflunomide | Human Prescription Drug Label | 1 | 50090-5992 | TABLET, FILM COATED | 20 mg | ORAL | ANDA | 26 sections |
LEFLUNOMIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50268-477 | TABLET | 10 mg | ORAL | ANDA | 18 sections |
LEFLUNOMIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50268-478 | TABLET | 20 mg | ORAL | ANDA | 18 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 54868-2319 | TABLET, FILM COATED | 20 mg | ORAL | ANDA | 26 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 54868-6170 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 26 sections |
Leflunomide | Human Prescription Drug Label | 1 | 59651-348 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 26 sections |
Leflunomide | Human Prescription Drug Label | 1 | 59651-349 | TABLET, FILM COATED | 20 mg | ORAL | ANDA | 26 sections |
LEFLUNOMIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 60505-2502 | TABLET | 10 mg | ORAL | ANDA | 18 sections |