Stem definition | Drug id | CAS RN |
---|---|---|
1552 | 75706-12-6 |
Dose | Unit | Route |
---|---|---|
20 | mg | O |
Property | Value | Reference |
---|---|---|
BDDCS (Biopharmaceutical Drug Disposition Classification System) | 2 | Benet LZ, Broccatelli F, Oprea TI |
S (Water solubility) | 0.02 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
EoM (Fraction excreted unchanged in urine) | 1 % | Benet LZ, Broccatelli F, Oprea TI |
MRTD (Maximum Recommended Therapeutic Daily Dose) | 1.23 ยตM/kg/day | Contrera JF, Matthews EJ, Kruhlak NL, Benz RD |
BA (Bioavailability) | 80 % | Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H |
fu (Fraction unbound in plasma) | 0.00 % | Kawashima H, Watanabe R, Esaki T, Kuroda M, Nagao C, Natsume-Kitatani Y, Ohashi R, Komura H, Mizuguchi K |
Date | Agency | Company | Orphan |
---|---|---|---|
Sept. 2, 1999 | EMA | Sanofi-aventis Deutschland GmbH | |
Sept. 10, 1998 | FDA | SANOFI AVENTIS US |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug ineffective | 6652.86 | 14.64 | 18828 | 417845 | 1025937 | 62026412 |
Drug intolerance | 5071.13 | 14.64 | 8218 | 428455 | 300443 | 62751906 |
Contraindicated product administered | 4291.84 | 14.64 | 6310 | 430363 | 211338 | 62841011 |
Joint swelling | 3787.29 | 14.64 | 7487 | 429186 | 320179 | 62732170 |
Rheumatoid arthritis | 3725.76 | 14.64 | 6431 | 430242 | 247388 | 62804961 |
Synovitis | 3113.05 | 14.64 | 5015 | 431658 | 181903 | 62870446 |
Treatment failure | 3022.84 | 14.64 | 5123 | 431550 | 193920 | 62858429 |
Arthropathy | 2745.07 | 14.64 | 5396 | 431277 | 229396 | 62822953 |
Therapeutic product effect decreased | 2494.84 | 14.64 | 4633 | 432040 | 188554 | 62863795 |
Pemphigus | 2378.22 | 14.64 | 4411 | 432262 | 179315 | 62873034 |
Systemic lupus erythematosus | 2196.10 | 14.64 | 4596 | 432077 | 204322 | 62848027 |
Abdominal discomfort | 2059.19 | 14.64 | 5834 | 430839 | 315051 | 62737298 |
Swelling | 2038.34 | 14.64 | 5278 | 431395 | 270100 | 62782249 |
Glossodynia | 1967.15 | 14.64 | 4010 | 432663 | 174866 | 62877483 |
Hand deformity | 1957.75 | 14.64 | 3744 | 432929 | 155713 | 62896636 |
Alopecia | 1896.26 | 14.64 | 5854 | 430819 | 331682 | 62720667 |
Pain | 1584.42 | 14.64 | 9574 | 427099 | 731054 | 62321295 |
Death | 1530.18 | 14.64 | 351 | 436322 | 374030 | 62678319 |
Hepatic enzyme increased | 1397.42 | 14.64 | 3782 | 432891 | 198546 | 62853803 |
Arthralgia | 1301.07 | 14.64 | 7498 | 429175 | 562212 | 62490137 |
Anti-cyclic citrullinated peptide antibody positive | 1273.36 | 14.64 | 2603 | 434070 | 113609 | 62938740 |
Wound | 1241.33 | 14.64 | 3164 | 433509 | 160099 | 62892250 |
Hypersensitivity | 1131.18 | 14.64 | 4489 | 432184 | 288196 | 62764153 |
Rheumatoid factor positive | 1111.80 | 14.64 | 2044 | 434629 | 82362 | 62969987 |
Acute kidney injury | 1065.44 | 14.64 | 252 | 436421 | 263163 | 62789186 |
Pericarditis | 1033.18 | 14.64 | 2582 | 434091 | 128997 | 62923352 |
Hypotension | 1031.71 | 14.64 | 298 | 436375 | 272306 | 62780043 |
Peripheral swelling | 1020.11 | 14.64 | 4070 | 432603 | 261872 | 62790477 |
Musculoskeletal stiffness | 1012.40 | 14.64 | 3179 | 433494 | 181439 | 62870910 |
Drug hypersensitivity | 938.97 | 14.64 | 4425 | 432248 | 306262 | 62746087 |
Constipation | 929.87 | 14.64 | 205 | 436468 | 224738 | 62827611 |
Toxicity to various agents | 926.87 | 14.64 | 275 | 436398 | 246975 | 62805374 |
Therapeutic product effect incomplete | 918.40 | 14.64 | 2393 | 434280 | 122663 | 62929686 |
Discomfort | 916.50 | 14.64 | 2881 | 433792 | 164493 | 62887856 |
Rash | 910.35 | 14.64 | 6779 | 429894 | 554092 | 62498257 |
Completed suicide | 908.70 | 14.64 | 19 | 436654 | 145654 | 62906695 |
C-reactive protein abnormal | 908.25 | 14.64 | 1339 | 435334 | 44757 | 63007592 |
Drug interaction | 807.19 | 14.64 | 284 | 436389 | 228847 | 62823502 |
Anaemia | 794.23 | 14.64 | 521 | 436152 | 292909 | 62759440 |
Folliculitis | 776.68 | 14.64 | 1581 | 435092 | 68736 | 62983613 |
Muscle injury | 767.01 | 14.64 | 1507 | 435166 | 63838 | 62988511 |
Psoriatic arthropathy | 742.36 | 14.64 | 1819 | 434854 | 89701 | 62962648 |
Infection | 734.39 | 14.64 | 3322 | 433351 | 225851 | 62826498 |
Product use issue | 731.00 | 14.64 | 3229 | 433444 | 217291 | 62835058 |
Impaired healing | 725.97 | 14.64 | 1936 | 434737 | 100606 | 62951743 |
Irritable bowel syndrome | 713.57 | 14.64 | 1680 | 434993 | 80732 | 62971617 |
Gastrointestinal disorder | 712.52 | 14.64 | 2253 | 434420 | 128986 | 62923363 |
Infusion related reaction | 704.87 | 14.64 | 3447 | 433226 | 242074 | 62810275 |
Helicobacter infection | 704.13 | 14.64 | 1798 | 434875 | 90987 | 62961362 |
Febrile neutropenia | 696.41 | 14.64 | 27 | 436646 | 118422 | 62933927 |
Lower respiratory tract infection | 683.48 | 14.64 | 2233 | 434440 | 130074 | 62922275 |
Duodenal ulcer perforation | 676.38 | 14.64 | 1704 | 434969 | 85505 | 62966844 |
Dehydration | 643.57 | 14.64 | 196 | 436477 | 173158 | 62879191 |
Ill-defined disorder | 637.73 | 14.64 | 1601 | 435072 | 80154 | 62972195 |
Red blood cell sedimentation rate abnormal | 636.20 | 14.64 | 732 | 435941 | 19050 | 63033299 |
Loss of personal independence in daily activities | 616.42 | 14.64 | 1764 | 434909 | 95526 | 62956823 |
Hyponatraemia | 575.42 | 14.64 | 53 | 436620 | 111847 | 62940502 |
Blister | 574.38 | 14.64 | 2081 | 434592 | 127733 | 62924616 |
Red blood cell sedimentation rate increased | 573.58 | 14.64 | 1061 | 435612 | 42921 | 63009428 |
Tremor | 572.14 | 14.64 | 108 | 436565 | 132131 | 62920218 |
Product dose omission issue | 567.65 | 14.64 | 467 | 436206 | 233846 | 62818503 |
Condition aggravated | 560.17 | 14.64 | 4697 | 431976 | 397520 | 62654829 |
Seizure | 555.69 | 14.64 | 117 | 436556 | 132517 | 62919832 |
Sleep disorder due to general medical condition, insomnia type | 544.73 | 14.64 | 1147 | 435526 | 51070 | 63001279 |
Maternal exposure during pregnancy | 532.57 | 14.64 | 2947 | 433726 | 217115 | 62835234 |
Somnolence | 529.96 | 14.64 | 284 | 436389 | 178401 | 62873948 |
Fall | 514.09 | 14.64 | 1218 | 435455 | 391116 | 62661233 |
C-reactive protein increased | 501.12 | 14.64 | 1612 | 435061 | 93095 | 62959254 |
Disease progression | 488.85 | 14.64 | 121 | 436552 | 122637 | 62929712 |
Intentional overdose | 473.28 | 14.64 | 7 | 436666 | 74145 | 62978204 |
Overdose | 462.98 | 14.64 | 111 | 436562 | 114967 | 62937382 |
Cardiac arrest | 454.66 | 14.64 | 52 | 436621 | 92493 | 62959856 |
Anxiety | 450.42 | 14.64 | 499 | 436174 | 217042 | 62835307 |
Urinary tract infection | 445.26 | 14.64 | 708 | 435965 | 263976 | 62788373 |
Dizziness | 444.80 | 14.64 | 1495 | 435178 | 428430 | 62623919 |
Bradycardia | 436.22 | 14.64 | 15 | 436658 | 73212 | 62979137 |
Mobility decreased | 430.70 | 14.64 | 1813 | 434860 | 119346 | 62933003 |
Thrombocytopenia | 424.18 | 14.64 | 257 | 436416 | 150900 | 62901449 |
Bone erosion | 416.13 | 14.64 | 560 | 436113 | 17157 | 63035192 |
Dyspnoea | 414.89 | 14.64 | 2757 | 433916 | 658556 | 62393793 |
Knee arthroplasty | 406.42 | 14.64 | 1046 | 435627 | 53160 | 62999189 |
Rheumatoid nodule | 404.09 | 14.64 | 543 | 436130 | 16612 | 63035737 |
Neutropenia | 387.48 | 14.64 | 379 | 436294 | 174626 | 62877723 |
Hypokalaemia | 380.36 | 14.64 | 120 | 436553 | 103684 | 62948665 |
Electrocardiogram QT prolonged | 366.27 | 14.64 | 9 | 436664 | 59521 | 62992828 |
Sepsis | 361.02 | 14.64 | 313 | 436360 | 152810 | 62899539 |
Tachycardia | 354.33 | 14.64 | 185 | 436488 | 117971 | 62934378 |
Blood iron abnormal | 347.55 | 14.64 | 255 | 436418 | 3621 | 63048728 |
Chest discomfort | 346.68 | 14.64 | 161 | 436512 | 109808 | 62942541 |
Hip arthroplasty | 344.44 | 14.64 | 907 | 435766 | 46739 | 63005610 |
Stomatitis | 340.03 | 14.64 | 1865 | 434808 | 136860 | 62915489 |
Depressed level of consciousness | 331.21 | 14.64 | 25 | 436648 | 62053 | 62990296 |
Vision blurred | 326.71 | 14.64 | 112 | 436561 | 91812 | 62960537 |
Suicide attempt | 326.53 | 14.64 | 24 | 436649 | 60894 | 62991455 |
Blood cholesterol increased | 320.11 | 14.64 | 1389 | 435284 | 92643 | 62959706 |
Balance disorder | 319.43 | 14.64 | 92 | 436581 | 84330 | 62968019 |
Platelet count decreased | 304.56 | 14.64 | 213 | 436460 | 115909 | 62936440 |
Rheumatic fever | 303.84 | 14.64 | 813 | 435860 | 42298 | 63010051 |
Abdominal pain | 303.38 | 14.64 | 1020 | 435653 | 292436 | 62759913 |
Oedema peripheral | 301.72 | 14.64 | 525 | 436148 | 188986 | 62863363 |
Osteoarthritis | 300.91 | 14.64 | 1377 | 435296 | 93966 | 62958383 |
Foot deformity | 292.92 | 14.64 | 614 | 436059 | 27239 | 63025110 |
Hyperkalaemia | 291.54 | 14.64 | 21 | 436652 | 54182 | 62998167 |
Pulmonary embolism | 288.00 | 14.64 | 228 | 436445 | 116456 | 62935893 |
Atrial fibrillation | 285.25 | 14.64 | 230 | 436443 | 116406 | 62935943 |
Inflammation | 285.16 | 14.64 | 1222 | 435451 | 81051 | 62971298 |
Swollen joint count increased | 281.94 | 14.64 | 707 | 435966 | 35347 | 63017002 |
Respiratory failure | 281.76 | 14.64 | 176 | 436497 | 101682 | 62950667 |
Cough | 272.50 | 14.64 | 1063 | 435610 | 291680 | 62760669 |
Cardio-respiratory arrest | 272.34 | 14.64 | 43 | 436630 | 59916 | 62992433 |
Hallucination | 271.23 | 14.64 | 30 | 436643 | 54787 | 62997562 |
Cerebrovascular accident | 270.50 | 14.64 | 208 | 436465 | 107816 | 62944533 |
Sinusitis | 270.38 | 14.64 | 2561 | 434112 | 224092 | 62828257 |
Agitation | 266.62 | 14.64 | 45 | 436628 | 59712 | 62992637 |
Neutrophil count decreased | 266.51 | 14.64 | 36 | 436637 | 56370 | 62995979 |
Hypoglycaemia | 261.95 | 14.64 | 48 | 436625 | 60017 | 62992332 |
Asthenia | 259.98 | 14.64 | 1560 | 435113 | 382044 | 62670305 |
Epistaxis | 259.48 | 14.64 | 88 | 436585 | 72637 | 62979712 |
Muscle spasms | 257.34 | 14.64 | 423 | 436250 | 155727 | 62896622 |
Cognitive disorder | 255.84 | 14.64 | 39 | 436634 | 55776 | 62996573 |
COVID-19 | 254.84 | 14.64 | 241 | 436432 | 112862 | 62939487 |
Deformity | 251.34 | 14.64 | 354 | 436319 | 11330 | 63041019 |
Gastrointestinal haemorrhage | 250.99 | 14.64 | 122 | 436551 | 81054 | 62971295 |
Fibromyalgia | 247.46 | 14.64 | 1153 | 435520 | 79267 | 62973082 |
Tenosynovitis | 246.42 | 14.64 | 383 | 436290 | 13412 | 63038937 |
Sedation | 246.20 | 14.64 | 4 | 436669 | 38805 | 63013544 |
Hypoxia | 245.74 | 14.64 | 55 | 436618 | 59737 | 62992612 |
Osteoporosis | 243.91 | 14.64 | 908 | 435765 | 56430 | 62995919 |
Metabolic acidosis | 243.72 | 14.64 | 17 | 436656 | 45052 | 63007297 |
Cardiac failure congestive | 243.09 | 14.64 | 169 | 436504 | 92264 | 62960085 |
Chest pain | 241.02 | 14.64 | 725 | 435948 | 215234 | 62837115 |
Blood glucose increased | 239.66 | 14.64 | 139 | 436534 | 83617 | 62968732 |
Haemoglobin decreased | 238.90 | 14.64 | 395 | 436278 | 145090 | 62907259 |
Drug tolerance decreased | 235.91 | 14.64 | 428 | 436245 | 17045 | 63035304 |
Arthritis | 234.56 | 14.64 | 1482 | 435191 | 114439 | 62937910 |
Musculoskeletal disorder | 233.50 | 14.64 | 469 | 436204 | 20175 | 63032174 |
Wrong technique in product usage process | 232.05 | 14.64 | 70 | 436603 | 62270 | 62990079 |
Pulmonary fibrosis | 231.08 | 14.64 | 700 | 435973 | 39109 | 63013240 |
Syncope | 229.06 | 14.64 | 282 | 436391 | 117103 | 62935246 |
Hyperhidrosis | 227.82 | 14.64 | 243 | 436430 | 107593 | 62944756 |
Cardiac failure | 225.27 | 14.64 | 170 | 436503 | 88972 | 62963377 |
Myalgia | 224.12 | 14.64 | 416 | 436257 | 146113 | 62906236 |
Joint range of motion decreased | 220.93 | 14.64 | 604 | 436069 | 31824 | 63020525 |
Pancytopenia | 219.00 | 14.64 | 206 | 436467 | 96727 | 62955622 |
Lactic acidosis | 217.48 | 14.64 | 11 | 436662 | 38276 | 63014073 |
Dysphagia | 216.19 | 14.64 | 175 | 436498 | 88410 | 62963939 |
Renal failure | 215.82 | 14.64 | 296 | 436377 | 117356 | 62934993 |
Flushing | 212.87 | 14.64 | 126 | 436547 | 74961 | 62977388 |
Unresponsive to stimuli | 212.39 | 14.64 | 4 | 436669 | 33812 | 63018537 |
Feeling abnormal | 209.12 | 14.64 | 442 | 436231 | 147950 | 62904399 |
Disability | 206.53 | 14.64 | 416 | 436257 | 17931 | 63034418 |
Bone pain | 205.85 | 14.64 | 60 | 436613 | 54581 | 62997768 |
Chills | 205.21 | 14.64 | 288 | 436385 | 113090 | 62939259 |
Plasma cell myeloma | 204.95 | 14.64 | 10 | 436663 | 35895 | 63016454 |
Granuloma skin | 204.74 | 14.64 | 271 | 436402 | 8166 | 63044183 |
Coma | 204.73 | 14.64 | 93 | 436580 | 64271 | 62988078 |
Nausea | 201.62 | 14.64 | 4415 | 432258 | 850056 | 62202293 |
White blood cell count decreased | 200.51 | 14.64 | 409 | 436264 | 138695 | 62913654 |
Mental status changes | 200.20 | 14.64 | 20 | 436653 | 39579 | 63012770 |
Blood parathyroid hormone decreased | 199.37 | 14.64 | 289 | 436384 | 9502 | 63042847 |
Pneumonia aspiration | 199.17 | 14.64 | 9 | 436664 | 34531 | 63017818 |
Adverse event | 198.64 | 14.64 | 956 | 435717 | 66603 | 62985746 |
Joint stiffness | 198.48 | 14.64 | 687 | 435986 | 41182 | 63011167 |
International normalised ratio increased | 198.40 | 14.64 | 39 | 436634 | 46386 | 63005963 |
Panniculitis | 197.67 | 14.64 | 312 | 436361 | 11073 | 63041276 |
Neuropathy peripheral | 194.72 | 14.64 | 300 | 436373 | 113367 | 62938982 |
Pleural effusion | 193.60 | 14.64 | 213 | 436460 | 92997 | 62959352 |
Liver injury | 192.30 | 14.64 | 876 | 435797 | 59644 | 62992705 |
Therapeutic response decreased | 192.13 | 14.64 | 886 | 435787 | 60639 | 62991710 |
Lethargy | 190.90 | 14.64 | 73 | 436600 | 55934 | 62996415 |
Pulmonary oedema | 187.90 | 14.64 | 71 | 436602 | 54802 | 62997547 |
Respiratory arrest | 186.63 | 14.64 | 9 | 436664 | 32636 | 63019713 |
Gastrooesophageal reflux disease | 186.32 | 14.64 | 230 | 436443 | 95409 | 62956940 |
Deep vein thrombosis | 184.75 | 14.64 | 182 | 436491 | 83618 | 62968731 |
Hyperglycaemia | 183.55 | 14.64 | 33 | 436640 | 41834 | 63010515 |
Blood pressure decreased | 181.67 | 14.64 | 111 | 436562 | 64911 | 62987438 |
Vomiting | 181.62 | 14.64 | 2733 | 433940 | 556884 | 62495465 |
Encephalopathy | 181.61 | 14.64 | 25 | 436648 | 38595 | 63013754 |
Deafness transitory | 177.52 | 14.64 | 130 | 436543 | 1840 | 63050509 |
Rhabdomyolysis | 177.47 | 14.64 | 42 | 436631 | 43909 | 63008440 |
Grip strength decreased | 176.29 | 14.64 | 439 | 436234 | 21848 | 63030501 |
Finger deformity | 176.08 | 14.64 | 241 | 436432 | 7504 | 63044845 |
Nasopharyngitis | 174.44 | 14.64 | 2584 | 434089 | 251673 | 62800676 |
Disturbance in attention | 174.30 | 14.64 | 27 | 436646 | 38162 | 63014187 |
Orthostatic hypotension | 173.41 | 14.64 | 22 | 436651 | 36138 | 63016211 |
Fluid retention | 167.99 | 14.64 | 101 | 436572 | 59585 | 62992764 |
Asthma | 165.81 | 14.64 | 397 | 436276 | 127164 | 62925185 |
Type 2 diabetes mellitus | 164.70 | 14.64 | 871 | 435802 | 62997 | 62989352 |
Intentional product misuse | 164.68 | 14.64 | 108 | 436565 | 60809 | 62991540 |
Dysarthria | 164.41 | 14.64 | 45 | 436628 | 42666 | 63009683 |
Adverse drug reaction | 164.23 | 14.64 | 1024 | 435649 | 78690 | 62973659 |
Restlessness | 162.53 | 14.64 | 10 | 436663 | 29443 | 63022906 |
Ascites | 162.34 | 14.64 | 40 | 436633 | 40688 | 63011661 |
Intentional self-injury | 161.48 | 14.64 | 3 | 436670 | 25684 | 63026665 |
Diarrhoea | 161.39 | 14.64 | 3721 | 432952 | 711645 | 62340704 |
Decreased appetite | 157.95 | 14.64 | 1044 | 435629 | 250008 | 62802341 |
Drug withdrawal syndrome | 157.08 | 14.64 | 7 | 436666 | 27187 | 63025162 |
Premature delivery | 156.52 | 14.64 | 14 | 436659 | 30267 | 63022082 |
Dry skin | 156.31 | 14.64 | 99 | 436574 | 56788 | 62995561 |
Palpitations | 154.61 | 14.64 | 341 | 436332 | 112429 | 62939920 |
Depression | 154.39 | 14.64 | 760 | 435913 | 195732 | 62856617 |
Rectal haemorrhage | 154.13 | 14.64 | 72 | 436601 | 48958 | 63003391 |
Urinary retention | 153.98 | 14.64 | 15 | 436658 | 30286 | 63022063 |
Dysgeusia | 152.48 | 14.64 | 65 | 436608 | 46645 | 63005704 |
Liver function test increased | 150.00 | 14.64 | 532 | 436141 | 32279 | 63020070 |
Pneumonia | 150.00 | 14.64 | 2225 | 434448 | 454542 | 62597807 |
Hypervolaemia | 149.98 | 14.64 | 12 | 436661 | 28401 | 63023948 |
Injection site pain | 149.61 | 14.64 | 429 | 436244 | 129371 | 62922978 |
Full blood count decreased | 149.34 | 14.64 | 7 | 436666 | 26017 | 63026332 |
Skin ulcer | 148.04 | 14.64 | 638 | 436035 | 42407 | 63009942 |
Disorientation | 145.55 | 14.64 | 45 | 436628 | 39407 | 63012942 |
Blood potassium decreased | 144.52 | 14.64 | 54 | 436619 | 41972 | 63010377 |
Hospitalisation | 143.37 | 14.64 | 227 | 436446 | 84854 | 62967495 |
Respiratory distress | 142.00 | 14.64 | 30 | 436643 | 33921 | 63018428 |
Chronic obstructive pulmonary disease | 141.83 | 14.64 | 133 | 436540 | 62553 | 62989796 |
Suicidal ideation | 141.75 | 14.64 | 132 | 436541 | 62289 | 62990060 |
Hypomagnesaemia | 141.47 | 14.64 | 16 | 436657 | 28721 | 63023628 |
Multiple organ dysfunction syndrome | 141.11 | 14.64 | 110 | 436563 | 56642 | 62995707 |
Dyskinesia | 140.77 | 14.64 | 25 | 436648 | 31977 | 63020372 |
Paraesthesia | 140.15 | 14.64 | 579 | 436094 | 156387 | 62895962 |
Cerebral haemorrhage | 139.62 | 14.64 | 22 | 436651 | 30707 | 63021642 |
Rheumatoid lung | 138.44 | 14.64 | 151 | 436522 | 3697 | 63048652 |
Erythema | 137.93 | 14.64 | 680 | 435993 | 175071 | 62877278 |
Chronic kidney disease | 137.64 | 14.64 | 70 | 436603 | 45328 | 63007021 |
Skin necrosis | 136.85 | 14.64 | 299 | 436374 | 13651 | 63038698 |
Fatigue | 136.01 | 14.64 | 7431 | 429242 | 880597 | 62171752 |
Oxygen saturation decreased | 135.84 | 14.64 | 251 | 436422 | 88334 | 62964015 |
Pyrexia | 135.71 | 14.64 | 2348 | 434325 | 468130 | 62584219 |
Limb deformity | 135.28 | 14.64 | 152 | 436521 | 3850 | 63048499 |
Haemorrhage | 135.11 | 14.64 | 132 | 436541 | 60890 | 62991459 |
Thrombosis | 133.33 | 14.64 | 149 | 436524 | 64606 | 62987743 |
Melaena | 132.96 | 14.64 | 24 | 436649 | 30341 | 63022008 |
Altered state of consciousness | 132.22 | 14.64 | 11 | 436662 | 25219 | 63027130 |
Dyspnoea exertional | 131.72 | 14.64 | 132 | 436541 | 60170 | 62992179 |
Haematochezia | 131.59 | 14.64 | 105 | 436568 | 53439 | 62998910 |
Haematoma | 131.58 | 14.64 | 38 | 436635 | 34782 | 63017567 |
Urinary incontinence | 130.43 | 14.64 | 30 | 436643 | 31984 | 63020365 |
Heart rate increased | 129.97 | 14.64 | 284 | 436389 | 93954 | 62958395 |
Blood calcium decreased | 129.53 | 14.64 | 15 | 436658 | 26436 | 63025913 |
Generalised tonic-clonic seizure | 129.09 | 14.64 | 22 | 436651 | 28994 | 63023355 |
Aphasia | 128.47 | 14.64 | 34 | 436639 | 32966 | 63019383 |
Blood creatinine increased | 127.64 | 14.64 | 257 | 436416 | 87587 | 62964762 |
Lymphocyte count decreased | 126.00 | 14.64 | 27 | 436646 | 30230 | 63022119 |
Metastases to liver | 124.73 | 14.64 | 10 | 436663 | 23629 | 63028720 |
Inappropriate schedule of product administration | 124.71 | 14.64 | 337 | 436336 | 103628 | 62948721 |
Product quality issue | 123.47 | 14.64 | 46 | 436627 | 35819 | 63016530 |
Full blood count abnormal | 122.86 | 14.64 | 33 | 436640 | 31684 | 63020665 |
Musculoskeletal deformity | 122.30 | 14.64 | 103 | 436570 | 1806 | 63050543 |
Pulmonary toxicity | 121.83 | 14.64 | 227 | 436446 | 9228 | 63043121 |
Depressed mood | 121.80 | 14.64 | 62 | 436611 | 40129 | 63012220 |
Adverse reaction | 121.65 | 14.64 | 237 | 436436 | 9966 | 63042383 |
Oropharyngeal pain | 121.24 | 14.64 | 296 | 436377 | 94191 | 62958158 |
Drug reaction with eosinophilia and systemic symptoms | 120.58 | 14.64 | 41 | 436632 | 33795 | 63018554 |
Dysuria | 120.02 | 14.64 | 41 | 436632 | 33697 | 63018652 |
Night sweats | 119.93 | 14.64 | 657 | 436016 | 48157 | 63004192 |
Abnormal behaviour | 119.06 | 14.64 | 7 | 436666 | 21419 | 63030930 |
Drug level increased | 118.90 | 14.64 | 10 | 436663 | 22726 | 63029623 |
Sciatica | 118.22 | 14.64 | 509 | 436164 | 33815 | 63018534 |
Intentional product use issue | 117.35 | 14.64 | 1371 | 435302 | 126521 | 62925828 |
Presyncope | 117.34 | 14.64 | 24 | 436649 | 27761 | 63024588 |
Incorrect dose administered | 114.91 | 14.64 | 146 | 436527 | 59822 | 62992527 |
Cardiac disorder | 114.74 | 14.64 | 108 | 436565 | 50708 | 63001641 |
Irritability | 113.65 | 14.64 | 38 | 436635 | 31656 | 63020693 |
Ejection fraction decreased | 113.62 | 14.64 | 11 | 436662 | 22321 | 63030028 |
Vertigo | 113.52 | 14.64 | 147 | 436526 | 59740 | 62992609 |
Aggression | 113.40 | 14.64 | 14 | 436659 | 23484 | 63028865 |
Nodule | 113.00 | 14.64 | 360 | 436313 | 20666 | 63031683 |
Colitis | 112.11 | 14.64 | 101 | 436572 | 48427 | 63003922 |
Abdominal distension | 111.39 | 14.64 | 271 | 436402 | 86344 | 62966005 |
Device dislocation | 111.09 | 14.64 | 21 | 436652 | 25684 | 63026665 |
Acute respiratory failure | 110.95 | 14.64 | 49 | 436624 | 34436 | 63017913 |
Sleep disorder | 108.95 | 14.64 | 945 | 435728 | 80621 | 62971728 |
Therapy interrupted | 107.81 | 14.64 | 44 | 436629 | 32411 | 63019938 |
Flatulence | 107.48 | 14.64 | 52 | 436621 | 34650 | 63017699 |
Muscle spasticity | 107.12 | 14.64 | 362 | 436311 | 21432 | 63030917 |
Psychotic disorder | 106.96 | 14.64 | 23 | 436650 | 25689 | 63026660 |
Joint destruction | 106.70 | 14.64 | 170 | 436503 | 6082 | 63046267 |
Metastases to bone | 105.25 | 14.64 | 11 | 436662 | 21008 | 63031341 |
Accidental overdose | 105.19 | 14.64 | 17 | 436656 | 23292 | 63029057 |
Foetal exposure during pregnancy | 105.09 | 14.64 | 44 | 436629 | 31918 | 63020431 |
Ear pain | 104.62 | 14.64 | 509 | 436164 | 35609 | 63016740 |
Right ventricular failure | 104.21 | 14.64 | 3 | 436670 | 17185 | 63035164 |
Pulmonary hypertension | 104.21 | 14.64 | 63 | 436610 | 37060 | 63015289 |
Ventricular tachycardia | 103.90 | 14.64 | 9 | 436664 | 19970 | 63032379 |
Foot operation | 103.87 | 14.64 | 182 | 436491 | 7049 | 63045300 |
Rash erythematous | 103.66 | 14.64 | 84 | 436589 | 42426 | 63009923 |
Hallucination, visual | 102.28 | 14.64 | 8 | 436665 | 19290 | 63033059 |
Pancreatitis acute | 102.00 | 14.64 | 30 | 436643 | 27136 | 63025213 |
Joint effusion | 101.83 | 14.64 | 303 | 436370 | 16757 | 63035592 |
Withdrawal syndrome | 101.34 | 14.64 | 10 | 436663 | 19987 | 63032362 |
Arrhythmia | 101.22 | 14.64 | 69 | 436604 | 38071 | 63014278 |
Mucosal inflammation | 101.04 | 14.64 | 104 | 436569 | 46824 | 63005525 |
Sleep apnoea syndrome | 100.90 | 14.64 | 37 | 436636 | 29096 | 63023253 |
Blood urea increased | 99.29 | 14.64 | 29 | 436644 | 26350 | 63025999 |
Neutropenic sepsis | 99.19 | 14.64 | 3 | 436670 | 16435 | 63035914 |
Pallor | 99.03 | 14.64 | 43 | 436630 | 30525 | 63021824 |
Toxic epidermal necrolysis | 98.81 | 14.64 | 26 | 436647 | 25308 | 63027041 |
Impaired work ability | 98.32 | 14.64 | 304 | 436369 | 17171 | 63035178 |
Musculoskeletal pain | 97.83 | 14.64 | 1018 | 435655 | 91259 | 62961090 |
Clostridium difficile colitis | 97.46 | 14.64 | 13 | 436660 | 20556 | 63031793 |
Abdominal pain lower | 97.07 | 14.64 | 28 | 436645 | 25650 | 63026699 |
Red blood cell sedimentation rate | 96.97 | 14.64 | 142 | 436531 | 4712 | 63047637 |
Therapy cessation | 96.85 | 14.64 | 44 | 436629 | 30413 | 63021936 |
Circulatory collapse | 96.79 | 14.64 | 17 | 436656 | 21921 | 63030428 |
Drug ineffective for unapproved indication | 96.75 | 14.64 | 57 | 436616 | 34006 | 63018343 |
Burning sensation | 96.63 | 14.64 | 140 | 436533 | 54267 | 62998082 |
Sinus tachycardia | 96.39 | 14.64 | 24 | 436649 | 24244 | 63028105 |
Dementia | 96.30 | 14.64 | 9 | 436664 | 18785 | 63033564 |
Shoulder arthroplasty | 96.26 | 14.64 | 128 | 436545 | 3874 | 63048475 |
Neurotoxicity | 96.11 | 14.64 | 5 | 436668 | 16985 | 63035364 |
Weight decreased | 96.07 | 14.64 | 1333 | 435340 | 275465 | 62776884 |
Tinnitus | 95.16 | 14.64 | 64 | 436609 | 35564 | 63016785 |
Blood creatine phosphokinase increased | 95.16 | 14.64 | 45 | 436628 | 30385 | 63021964 |
Vaginal haemorrhage | 95.05 | 14.64 | 35 | 436638 | 27452 | 63024897 |
Pericardial effusion | 94.69 | 14.64 | 44 | 436629 | 30014 | 63022335 |
Myocardial infarction | 94.51 | 14.64 | 360 | 436313 | 99533 | 62952816 |
Cholelithiasis | 93.83 | 14.64 | 98 | 436575 | 43827 | 63008522 |
Angioedema | 93.76 | 14.64 | 115 | 436558 | 47850 | 63004499 |
Abortion spontaneous | 93.48 | 14.64 | 112 | 436561 | 47083 | 63005266 |
Tuberculin test positive | 93.36 | 14.64 | 118 | 436555 | 3393 | 63048956 |
Oral mucosal exfoliation | 93.33 | 14.64 | 83 | 436590 | 1571 | 63050778 |
Gastrointestinal pain | 93.03 | 14.64 | 207 | 436466 | 9569 | 63042780 |
Enthesopathy | 93.02 | 14.64 | 192 | 436481 | 8422 | 63043927 |
Transient ischaemic attack | 92.81 | 14.64 | 74 | 436599 | 37679 | 63014670 |
Inappropriate antidiuretic hormone secretion | 92.66 | 14.64 | 3 | 436670 | 15459 | 63036890 |
Blood bilirubin increased | 92.31 | 14.64 | 72 | 436601 | 37068 | 63015281 |
Bone marrow failure | 92.08 | 14.64 | 43 | 436630 | 29247 | 63023102 |
Upper gastrointestinal haemorrhage | 91.54 | 14.64 | 11 | 436662 | 18841 | 63033508 |
Product administration error | 91.22 | 14.64 | 21 | 436652 | 22376 | 63029973 |
Pollakiuria | 90.98 | 14.64 | 39 | 436634 | 27898 | 63024451 |
Body temperature increased | 90.97 | 14.64 | 500 | 436173 | 36692 | 63015657 |
Blood sodium decreased | 90.66 | 14.64 | 27 | 436646 | 24225 | 63028124 |
Haemoptysis | 90.57 | 14.64 | 42 | 436631 | 28684 | 63023665 |
X-ray abnormal | 90.22 | 14.64 | 183 | 436490 | 7927 | 63044422 |
Lip swelling | 89.62 | 14.64 | 51 | 436622 | 31012 | 63021337 |
Septic shock | 89.24 | 14.64 | 204 | 436469 | 66425 | 62985924 |
Ankylosing spondylitis | 88.89 | 14.64 | 212 | 436461 | 10262 | 63042087 |
Physical disability | 88.86 | 14.64 | 102 | 436571 | 2646 | 63049703 |
Acute myocardial infarction | 88.11 | 14.64 | 56 | 436617 | 32068 | 63020281 |
Diabetic ketoacidosis | 88.08 | 14.64 | 17 | 436656 | 20488 | 63031861 |
Muscle twitching | 87.30 | 14.64 | 15 | 436658 | 19653 | 63032696 |
Haematuria | 86.84 | 14.64 | 46 | 436627 | 29111 | 63023238 |
Cholestasis | 86.84 | 14.64 | 47 | 436626 | 29387 | 63022962 |
Skin exfoliation | 86.74 | 14.64 | 101 | 436572 | 43001 | 63009348 |
Product prescribing error | 86.74 | 14.64 | 36 | 436637 | 26253 | 63026096 |
Memory impairment | 86.66 | 14.64 | 395 | 436278 | 103863 | 62948486 |
Swelling face | 85.29 | 14.64 | 194 | 436479 | 63281 | 62989068 |
Ulcer | 85.23 | 14.64 | 381 | 436292 | 25726 | 63026623 |
Feeling hot | 85.14 | 14.64 | 134 | 436539 | 50220 | 63002129 |
Hepatic function abnormal | 84.96 | 14.64 | 78 | 436595 | 37064 | 63015285 |
Face oedema | 84.24 | 14.64 | 18 | 436655 | 20194 | 63032155 |
Retinal toxicity | 84.18 | 14.64 | 70 | 436603 | 1205 | 63051144 |
Joint laxity | 83.99 | 14.64 | 94 | 436579 | 2370 | 63049979 |
Arthrodesis | 83.96 | 14.64 | 100 | 436573 | 2701 | 63049648 |
Renal impairment | 83.85 | 14.64 | 318 | 436355 | 88037 | 62964312 |
Cellulitis | 83.73 | 14.64 | 286 | 436387 | 81672 | 62970677 |
Head injury | 83.41 | 14.64 | 42 | 436631 | 27354 | 63024995 |
Hypocalcaemia | 83.32 | 14.64 | 58 | 436615 | 31655 | 63020694 |
Sinus bradycardia | 83.21 | 14.64 | 4 | 436669 | 14547 | 63037802 |
Creatinine renal clearance decreased | 83.05 | 14.64 | 8 | 436665 | 16300 | 63036049 |
Myoclonus | 82.92 | 14.64 | 7 | 436666 | 15861 | 63036488 |
Hepatotoxicity | 82.72 | 14.64 | 486 | 436187 | 36555 | 63015794 |
Leukocytosis | 81.64 | 14.64 | 38 | 436635 | 25897 | 63026452 |
Infusion site pain | 81.53 | 14.64 | 10 | 436663 | 16859 | 63035490 |
Panic attack | 81.43 | 14.64 | 26 | 436647 | 22305 | 63030044 |
Drug eruption | 81.41 | 14.64 | 402 | 436271 | 28292 | 63024057 |
Product substitution issue | 81.06 | 14.64 | 8 | 436665 | 15988 | 63036361 |
Macular degeneration | 81.04 | 14.64 | 33 | 436640 | 24343 | 63028006 |
Device issue | 81.02 | 14.64 | 31 | 436642 | 23750 | 63028599 |
Acute myeloid leukaemia | 80.85 | 14.64 | 11 | 436662 | 17136 | 63035213 |
Lacrimation increased | 80.79 | 14.64 | 21 | 436652 | 20610 | 63031739 |
Paraesthesia oral | 80.56 | 14.64 | 17 | 436656 | 19239 | 63033110 |
Rheumatoid factor negative | 80.51 | 14.64 | 51 | 436622 | 560 | 63051789 |
Hemiparesis | 79.91 | 14.64 | 30 | 436643 | 23252 | 63029097 |
Blood pressure increased | 79.28 | 14.64 | 722 | 435951 | 161340 | 62891009 |
Status epilepticus | 78.84 | 14.64 | 7 | 436666 | 15226 | 63037123 |
Pruritus allergic | 78.75 | 14.64 | 74 | 436599 | 1508 | 63050841 |
Mental disorder | 78.51 | 14.64 | 40 | 436633 | 25879 | 63026470 |
Cerebral infarction | 78.38 | 14.64 | 33 | 436640 | 23860 | 63028489 |
Dysphonia | 78.35 | 14.64 | 129 | 436544 | 47485 | 63004864 |
Electrolyte imbalance | 77.55 | 14.64 | 21 | 436652 | 20055 | 63032294 |
Disseminated intravascular coagulation | 77.32 | 14.64 | 18 | 436655 | 19033 | 63033316 |
Emotional distress | 77.29 | 14.64 | 66 | 436607 | 32483 | 63019866 |
Epilepsy | 77.28 | 14.64 | 45 | 436628 | 27020 | 63025329 |
Respiratory disorder | 76.71 | 14.64 | 496 | 436177 | 38586 | 63013763 |
Spinal column injury | 76.44 | 14.64 | 82 | 436591 | 1969 | 63050380 |
Stevens-Johnson syndrome | 76.34 | 14.64 | 38 | 436635 | 24912 | 63027437 |
Transfusion | 76.10 | 14.64 | 8 | 436665 | 15209 | 63037140 |
General physical health deterioration | 75.73 | 14.64 | 1867 | 434806 | 199535 | 62852814 |
Eye pain | 75.20 | 14.64 | 73 | 436600 | 33781 | 63018568 |
Small intestinal obstruction | 75.07 | 14.64 | 17 | 436656 | 18320 | 63034029 |
Coordination abnormal | 75.03 | 14.64 | 5 | 436668 | 13768 | 63038581 |
Accidental exposure to product | 74.86 | 14.64 | 48 | 436625 | 27357 | 63024992 |
Poisoning | 74.56 | 14.64 | 5 | 436668 | 13695 | 63038654 |
Surgical failure | 74.32 | 14.64 | 58 | 436615 | 908 | 63051441 |
Obstructive airways disorder | 73.89 | 14.64 | 25 | 436648 | 20674 | 63031675 |
Bacteraemia | 73.23 | 14.64 | 15 | 436658 | 17333 | 63035016 |
Agranulocytosis | 72.89 | 14.64 | 41 | 436632 | 25093 | 63027256 |
Labelled drug-drug interaction medication error | 72.60 | 14.64 | 5 | 436668 | 13394 | 63038955 |
Dystonia | 72.48 | 14.64 | 6 | 436667 | 13813 | 63038536 |
Intestinal obstruction | 71.74 | 14.64 | 64 | 436609 | 30835 | 63021514 |
Pain in jaw | 71.42 | 14.64 | 118 | 436555 | 43378 | 63008971 |
Dislocation of vertebra | 71.37 | 14.64 | 173 | 436500 | 8462 | 63043887 |
Loss of consciousness | 71.30 | 14.64 | 497 | 436176 | 117624 | 62934725 |
Renal disorder | 69.94 | 14.64 | 74 | 436599 | 32900 | 63019449 |
Diplopia | 69.84 | 14.64 | 38 | 436635 | 23690 | 63028659 |
Pulmonary arterial hypertension | 69.66 | 14.64 | 34 | 436639 | 22543 | 63029806 |
Seronegative arthritis | 69.43 | 14.64 | 109 | 436564 | 3850 | 63048499 |
Joint injury | 69.29 | 14.64 | 393 | 436280 | 29179 | 63023170 |
Hot flush | 69.02 | 14.64 | 156 | 436517 | 51003 | 63001346 |
Mania | 68.84 | 14.64 | 4 | 436669 | 12363 | 63039986 |
Wrist deformity | 68.77 | 14.64 | 79 | 436594 | 2051 | 63050298 |
Device difficult to use | 68.68 | 14.64 | 5 | 436668 | 12791 | 63039558 |
Swollen tongue | 68.48 | 14.64 | 83 | 436590 | 34717 | 63017632 |
Hypothermia | 68.28 | 14.64 | 7 | 436666 | 13574 | 63038775 |
Speech disorder | 67.86 | 14.64 | 109 | 436564 | 40520 | 63011829 |
Tuberculosis | 67.75 | 14.64 | 200 | 436473 | 11011 | 63041338 |
Eosinophilia | 67.62 | 14.64 | 36 | 436637 | 22720 | 63029629 |
Skin discolouration | 67.50 | 14.64 | 97 | 436576 | 37731 | 63014618 |
Paranoia | 67.47 | 14.64 | 3 | 436670 | 11676 | 63040673 |
Red cell distribution width decreased | 67.37 | 14.64 | 77 | 436596 | 1988 | 63050361 |
Haemorrhage intracranial | 67.25 | 14.64 | 7 | 436666 | 13412 | 63038937 |
Incontinence | 67.16 | 14.64 | 3 | 436670 | 11629 | 63040720 |
Exostosis | 67.07 | 14.64 | 272 | 436401 | 17590 | 63034759 |
Blood glucose decreased | 67.04 | 14.64 | 30 | 436643 | 20922 | 63031427 |
Bone swelling | 67.03 | 14.64 | 70 | 436603 | 1628 | 63050721 |
Complication associated with device | 67.03 | 14.64 | 17 | 436656 | 16961 | 63035388 |
Tachypnoea | 67.02 | 14.64 | 18 | 436655 | 17284 | 63035065 |
Cardiogenic shock | 66.96 | 14.64 | 20 | 436653 | 17912 | 63034437 |
Systemic lupus erythematosus rash | 66.85 | 14.64 | 80 | 436593 | 2172 | 63050177 |
Adjustment disorder with depressed mood | 66.46 | 14.64 | 187 | 436486 | 10017 | 63042332 |
Breast cancer stage III | 66.34 | 14.64 | 189 | 436484 | 10197 | 63042152 |
Frequent bowel movements | 66.13 | 14.64 | 38 | 436635 | 22984 | 63029365 |
Pancreatitis | 65.84 | 14.64 | 150 | 436523 | 48905 | 63003444 |
Vascular access complication | 65.78 | 14.64 | 77 | 436596 | 2041 | 63050308 |
Loose body in joint | 65.64 | 14.64 | 61 | 436612 | 1225 | 63051124 |
Basal cell carcinoma | 65.59 | 14.64 | 372 | 436301 | 27619 | 63024730 |
Metastases to central nervous system | 65.26 | 14.64 | 7 | 436666 | 13098 | 63039251 |
Anuria | 64.33 | 14.64 | 6 | 436667 | 12545 | 63039804 |
Visual acuity reduced | 64.17 | 14.64 | 35 | 436638 | 21791 | 63030558 |
Joint dislocation | 64.13 | 14.64 | 278 | 436395 | 18522 | 63033827 |
Premature labour | 64.03 | 14.64 | 6 | 436667 | 12498 | 63039851 |
Diabetes mellitus inadequate control | 64.01 | 14.64 | 13 | 436660 | 15113 | 63037236 |
Eye swelling | 63.83 | 14.64 | 43 | 436630 | 23875 | 63028474 |
Ischaemic stroke | 63.56 | 14.64 | 22 | 436651 | 17935 | 63034414 |
Subdural haematoma | 63.44 | 14.64 | 11 | 436662 | 14317 | 63038032 |
Metastases to lung | 63.01 | 14.64 | 7 | 436666 | 12743 | 63039606 |
Malnutrition | 62.99 | 14.64 | 14 | 436659 | 15284 | 63037065 |
Nervousness | 62.98 | 14.64 | 72 | 436601 | 30907 | 63021442 |
Product use in unapproved indication | 62.93 | 14.64 | 860 | 435813 | 178220 | 62874129 |
Clostridium difficile infection | 62.52 | 14.64 | 68 | 436605 | 29854 | 63022495 |
Influenza | 61.96 | 14.64 | 465 | 436208 | 108257 | 62944092 |
Respiratory depression | 61.90 | 14.64 | 10 | 436663 | 13705 | 63038644 |
Fear | 61.83 | 14.64 | 16 | 436657 | 15750 | 63036599 |
Mitral valve incompetence | 61.23 | 14.64 | 29 | 436644 | 19565 | 63032784 |
Nasal congestion | 61.21 | 14.64 | 238 | 436435 | 65422 | 62986927 |
Blood magnesium decreased | 60.98 | 14.64 | 9 | 436664 | 13189 | 63039160 |
Peritonitis | 60.75 | 14.64 | 21 | 436652 | 17133 | 63035216 |
Muscular weakness | 60.74 | 14.64 | 543 | 436130 | 121810 | 62930539 |
Left ventricular dysfunction | 60.74 | 14.64 | 6 | 436667 | 11982 | 63040367 |
Nightmare | 60.61 | 14.64 | 28 | 436645 | 19166 | 63033183 |
Incorrect product administration duration | 60.59 | 14.64 | 5 | 436668 | 11541 | 63040808 |
Mydriasis | 60.53 | 14.64 | 6 | 436667 | 11950 | 63040399 |
Viral infection | 60.20 | 14.64 | 95 | 436578 | 35568 | 63016781 |
Hepatic failure | 60.17 | 14.64 | 95 | 436578 | 35561 | 63016788 |
Ankle arthroplasty | 59.82 | 14.64 | 68 | 436605 | 1745 | 63050604 |
Therapeutic response unexpected | 59.80 | 14.64 | 27 | 436646 | 18732 | 63033617 |
Cyanosis | 59.51 | 14.64 | 21 | 436652 | 16914 | 63035435 |
Haematemesis | 59.35 | 14.64 | 73 | 436600 | 30339 | 63022010 |
Extrapyramidal disorder | 59.25 | 14.64 | 10 | 436663 | 13274 | 63039075 |
Mean platelet volume decreased | 59.09 | 14.64 | 82 | 436591 | 2587 | 63049762 |
Infusion site erythema | 58.77 | 14.64 | 6 | 436667 | 11673 | 63040676 |
Cholecystitis chronic | 58.76 | 14.64 | 3 | 436670 | 10358 | 63041991 |
Gastritis | 58.68 | 14.64 | 104 | 436569 | 37199 | 63015150 |
No adverse event | 58.55 | 14.64 | 123 | 436550 | 41282 | 63011067 |
Premature baby | 58.46 | 14.64 | 35 | 436638 | 20700 | 63031649 |
Caesarean section | 58.36 | 14.64 | 22 | 436651 | 17010 | 63035339 |
Myopathy | 58.31 | 14.64 | 5 | 436668 | 11186 | 63041163 |
International normalised ratio fluctuation | 57.68 | 14.64 | 78 | 436595 | 2400 | 63049949 |
Emotional disorder | 57.66 | 14.64 | 11 | 436662 | 13368 | 63038981 |
Ileus | 57.64 | 14.64 | 15 | 436658 | 14710 | 63037639 |
Muscle rigidity | 57.63 | 14.64 | 6 | 436667 | 11494 | 63040855 |
Demyelination | 57.58 | 14.64 | 139 | 436534 | 6781 | 63045568 |
Productive cough | 57.09 | 14.64 | 232 | 436441 | 62976 | 62989373 |
Retinitis | 56.50 | 14.64 | 129 | 436544 | 6067 | 63046282 |
Shock | 56.41 | 14.64 | 47 | 436626 | 23416 | 63028933 |
Aspiration | 56.12 | 14.64 | 5 | 436668 | 10846 | 63041503 |
Hypercholesterolaemia | 55.69 | 14.64 | 292 | 436381 | 21042 | 63031307 |
Mean cell volume decreased | 55.68 | 14.64 | 99 | 436574 | 3879 | 63048470 |
Cytomegalovirus infection | 55.47 | 14.64 | 38 | 436635 | 20914 | 63031435 |
Hypophosphataemia | 54.67 | 14.64 | 7 | 436666 | 11419 | 63040930 |
Hypersomnia | 54.49 | 14.64 | 28 | 436645 | 18027 | 63034322 |
Anti-cyclic citrullinated peptide antibody | 54.37 | 14.64 | 134 | 436539 | 6624 | 63045725 |
Investigation abnormal | 53.97 | 14.64 | 67 | 436606 | 1891 | 63050458 |
Hyperbilirubinaemia | 53.96 | 14.64 | 7 | 436666 | 11307 | 63041042 |
Device related infection | 53.65 | 14.64 | 49 | 436624 | 23343 | 63029006 |
Procedural pain | 53.36 | 14.64 | 42 | 436631 | 21527 | 63030822 |
Tricuspid valve incompetence | 53.35 | 14.64 | 17 | 436656 | 14604 | 63037745 |
Supraventricular tachycardia | 53.14 | 14.64 | 16 | 436657 | 14255 | 63038094 |
Ataxia | 53.13 | 14.64 | 19 | 436654 | 15176 | 63037173 |
Blindness | 52.75 | 14.64 | 43 | 436630 | 21656 | 63030693 |
Multiple fractures | 52.32 | 14.64 | 154 | 436519 | 8464 | 63043885 |
Blood calcium increased | 52.12 | 14.64 | 3 | 436670 | 9347 | 63043002 |
Infusion site swelling | 51.92 | 14.64 | 4 | 436669 | 9766 | 63042583 |
Myelosuppression | 51.62 | 14.64 | 52 | 436621 | 23651 | 63028698 |
Dermatitis atopic | 51.62 | 14.64 | 4 | 436669 | 9720 | 63042629 |
Hepatic encephalopathy | 51.43 | 14.64 | 8 | 436665 | 11274 | 63041075 |
Gait disturbance | 51.43 | 14.64 | 1636 | 435037 | 181542 | 62870807 |
Product label confusion | 51.27 | 14.64 | 63 | 436610 | 1759 | 63050590 |
Acidosis | 51.12 | 14.64 | 8 | 436665 | 11225 | 63041124 |
Anal incontinence | 50.95 | 14.64 | 15 | 436658 | 13561 | 63038788 |
Gastric disorder | 50.95 | 14.64 | 435 | 436238 | 36934 | 63015415 |
Back injury | 50.64 | 14.64 | 164 | 436509 | 9496 | 63042853 |
Ventricular fibrillation | 50.63 | 14.64 | 10 | 436663 | 11857 | 63040492 |
Ocular hyperaemia | 50.51 | 14.64 | 59 | 436614 | 25085 | 63027264 |
Multiple sclerosis | 50.25 | 14.64 | 56 | 436617 | 24316 | 63028033 |
Colitis ischaemic | 50.18 | 14.64 | 7 | 436666 | 10701 | 63041648 |
Retching | 50.04 | 14.64 | 19 | 436654 | 14626 | 63037723 |
Stress cardiomyopathy | 49.85 | 14.64 | 4 | 436669 | 9446 | 63042903 |
Tumour lysis syndrome | 49.76 | 14.64 | 3 | 436670 | 8987 | 63043362 |
Hip fracture | 49.29 | 14.64 | 79 | 436594 | 29395 | 63022954 |
Bloody discharge | 49.19 | 14.64 | 57 | 436616 | 1494 | 63050855 |
Mental impairment | 48.96 | 14.64 | 18 | 436655 | 14133 | 63038216 |
Tubulointerstitial nephritis | 48.93 | 14.64 | 39 | 436634 | 19864 | 63032485 |
Toxic skin eruption | 48.79 | 14.64 | 14 | 436659 | 12871 | 63039478 |
Infusion site reaction | 48.59 | 14.64 | 88 | 436585 | 3499 | 63048850 |
Onychomycosis | 48.40 | 14.64 | 142 | 436531 | 7790 | 63044559 |
Synovial cyst | 48.40 | 14.64 | 170 | 436503 | 10263 | 63042086 |
Jaundice | 48.36 | 14.64 | 79 | 436594 | 29172 | 63023177 |
Electrocardiogram abnormal | 48.10 | 14.64 | 4 | 436669 | 9175 | 63043174 |
Aplastic anaemia | 47.93 | 14.64 | 5 | 436668 | 9564 | 63042785 |
Rash macular | 47.82 | 14.64 | 54 | 436619 | 23310 | 63029039 |
Haemorrhoids | 47.78 | 14.64 | 49 | 436624 | 22101 | 63030248 |
Urine output decreased | 47.64 | 14.64 | 10 | 436663 | 11360 | 63040989 |
Bronchitis | 47.54 | 14.64 | 590 | 436083 | 124345 | 62928004 |
Acute respiratory distress syndrome | 47.51 | 14.64 | 55 | 436618 | 23479 | 63028870 |
Sensitivity to weather change | 47.50 | 14.64 | 133 | 436540 | 7104 | 63045245 |
Cystitis | 47.09 | 14.64 | 206 | 436467 | 54785 | 62997564 |
Hypothyroidism | 46.85 | 14.64 | 144 | 436529 | 42488 | 63009861 |
Coronary artery disease | 46.78 | 14.64 | 95 | 436578 | 32282 | 63020067 |
Abnormal dreams | 46.72 | 14.64 | 8 | 436665 | 10508 | 63041841 |
Contusion | 46.64 | 14.64 | 1357 | 435316 | 148687 | 62903662 |
Cardiomegaly | 46.56 | 14.64 | 32 | 436641 | 17582 | 63034767 |
Upper respiratory tract infection | 46.23 | 14.64 | 352 | 436321 | 81695 | 62970654 |
Lymphopenia | 46.21 | 14.64 | 35 | 436638 | 18292 | 63034057 |
Delusion | 45.61 | 14.64 | 13 | 436660 | 12004 | 63040345 |
Ventricular extrasystoles | 45.57 | 14.64 | 12 | 436661 | 11675 | 63040674 |
Injection site mass | 45.31 | 14.64 | 37 | 436636 | 18619 | 63033730 |
Central nervous system lesion | 45.29 | 14.64 | 9 | 436664 | 10626 | 63041723 |
Impaired quality of life | 45.27 | 14.64 | 19 | 436654 | 13764 | 63038585 |
Throat tightness | 45.21 | 14.64 | 63 | 436610 | 24824 | 63027525 |
Atrioventricular block complete | 44.93 | 14.64 | 3 | 436670 | 8248 | 63044101 |
Hepatic cytolysis | 44.87 | 14.64 | 25 | 436648 | 15382 | 63036967 |
Head discomfort | 44.86 | 14.64 | 18 | 436655 | 13397 | 63038952 |
Renal tubular necrosis | 44.81 | 14.64 | 13 | 436660 | 11865 | 63040484 |
Sinus disorder | 44.76 | 14.64 | 62 | 436611 | 24491 | 63027858 |
Malaise | 44.66 | 14.64 | 2372 | 434301 | 413582 | 62638767 |
Angina pectoris | 44.53 | 14.64 | 87 | 436586 | 29991 | 63022358 |
Troponin increased | 44.31 | 14.64 | 8 | 436665 | 10113 | 63042236 |
Mycotic allergy | 44.17 | 14.64 | 44 | 436629 | 966 | 63051383 |
Acute generalised exanthematous pustulosis | 44.03 | 14.64 | 11 | 436662 | 11088 | 63041261 |
Breast cancer metastatic | 43.81 | 14.64 | 14 | 436659 | 12004 | 63040345 |
Tardive dyskinesia | 43.75 | 14.64 | 4 | 436669 | 8498 | 63043851 |
Wrist surgery | 43.69 | 14.64 | 41 | 436632 | 834 | 63051515 |
Thirst | 43.54 | 14.64 | 21 | 436652 | 14020 | 63038329 |
Restless legs syndrome | 43.48 | 14.64 | 38 | 436635 | 18493 | 63033856 |
Seasonal allergy | 43.34 | 14.64 | 48 | 436625 | 20902 | 63031447 |
Muscle tightness | 43.13 | 14.64 | 14 | 436659 | 11886 | 63040463 |
Bone density abnormal | 43.05 | 14.64 | 81 | 436592 | 3317 | 63049032 |
Apathy | 43.02 | 14.64 | 5 | 436668 | 8789 | 63043560 |
Throat irritation | 42.92 | 14.64 | 125 | 436548 | 37522 | 63014827 |
Sensory loss | 42.91 | 14.64 | 9 | 436664 | 10229 | 63042120 |
Pre-eclampsia | 42.73 | 14.64 | 6 | 436667 | 9127 | 63043222 |
Hyperlipidaemia | 42.55 | 14.64 | 43 | 436630 | 19528 | 63032821 |
Hepatocellular injury | 42.47 | 14.64 | 77 | 436596 | 27304 | 63025045 |
Therapy non-responder | 42.41 | 14.64 | 746 | 435927 | 75155 | 62977194 |
Renal injury | 42.33 | 14.64 | 7 | 436666 | 9432 | 63042917 |
Faeces discoloured | 42.18 | 14.64 | 39 | 436634 | 18470 | 63033879 |
Food allergy | 42.06 | 14.64 | 13 | 436660 | 11388 | 63040961 |
Back pain | 42.02 | 14.64 | 1441 | 435232 | 262704 | 62789645 |
Illness | 41.87 | 14.64 | 184 | 436489 | 48875 | 63003474 |
Hypotonia | 41.39 | 14.64 | 7 | 436666 | 9278 | 63043071 |
Brain oedema | 41.39 | 14.64 | 23 | 436650 | 14172 | 63038177 |
Oesophagitis | 41.38 | 14.64 | 26 | 436647 | 14982 | 63037367 |
Influenza like illness | 41.38 | 14.64 | 279 | 436394 | 66545 | 62985804 |
Headache | 41.34 | 14.64 | 3772 | 432901 | 629469 | 62422880 |
Fine motor skill dysfunction | 41.31 | 14.64 | 98 | 436575 | 4727 | 63047622 |
Eosinophil count increased | 41.15 | 14.64 | 12 | 436661 | 10916 | 63041433 |
Device breakage | 41.10 | 14.64 | 14 | 436659 | 11528 | 63040821 |
Pharyngitis | 40.98 | 14.64 | 258 | 436415 | 19885 | 63032464 |
Amenorrhoea | 40.97 | 14.64 | 9 | 436664 | 9905 | 63042444 |
Feeling cold | 40.92 | 14.64 | 63 | 436610 | 23825 | 63028524 |
Injection site erythema | 40.88 | 14.64 | 370 | 436303 | 82804 | 62969545 |
Respiratory tract infection | 40.85 | 14.64 | 147 | 436526 | 41336 | 63011013 |
Shock haemorrhagic | 40.85 | 14.64 | 9 | 436664 | 9886 | 63042463 |
Haemodynamic instability | 40.81 | 14.64 | 7 | 436666 | 9183 | 63043166 |
Transaminases abnormal | 40.75 | 14.64 | 35 | 436638 | 631 | 63051718 |
Rhinitis allergic | 40.43 | 14.64 | 15 | 436658 | 11712 | 63040637 |
Oliguria | 40.26 | 14.64 | 7 | 436666 | 9094 | 63043255 |
Urticarial vasculitis | 40.17 | 14.64 | 35 | 436638 | 644 | 63051705 |
Prescribed overdose | 40.15 | 14.64 | 385 | 436288 | 33768 | 63018581 |
Bronchitis chronic | 40.11 | 14.64 | 91 | 436582 | 4262 | 63048087 |
Lower gastrointestinal haemorrhage | 39.84 | 14.64 | 4 | 436669 | 7886 | 63044463 |
Dermatitis contact | 39.81 | 14.64 | 13 | 436660 | 10995 | 63041354 |
Myelodysplastic syndrome | 39.74 | 14.64 | 34 | 436639 | 16720 | 63035629 |
Anticipatory anxiety | 39.72 | 14.64 | 46 | 436627 | 1205 | 63051144 |
Wheezing | 39.62 | 14.64 | 443 | 436230 | 95152 | 62957197 |
Chromaturia | 39.56 | 14.64 | 34 | 436639 | 16683 | 63035666 |
Ovarian cyst | 39.51 | 14.64 | 31 | 436642 | 15914 | 63036435 |
Coagulopathy | 39.37 | 14.64 | 50 | 436623 | 20494 | 63031855 |
Dactylitis | 39.16 | 14.64 | 67 | 436606 | 2545 | 63049804 |
Osteonecrosis of jaw | 39.05 | 14.64 | 118 | 436555 | 35005 | 63017344 |
Lupus-like syndrome | 39.00 | 14.64 | 208 | 436465 | 15087 | 63037262 |
Glomerular filtration rate decreased | 38.87 | 14.64 | 22 | 436651 | 13419 | 63038930 |
Fear of injection | 38.80 | 14.64 | 123 | 436550 | 7041 | 63045308 |
Atrioventricular block first degree | 38.58 | 14.64 | 3 | 436670 | 7270 | 63045079 |
Hepatitis | 38.46 | 14.64 | 431 | 436242 | 39357 | 63012992 |
Atelectasis | 38.42 | 14.64 | 55 | 436618 | 21428 | 63030921 |
Pneumonia viral | 38.41 | 14.64 | 131 | 436542 | 7791 | 63044558 |
Neuralgia | 38.37 | 14.64 | 75 | 436598 | 25851 | 63026498 |
Hyperthyroidism | 38.33 | 14.64 | 27 | 436646 | 14646 | 63037703 |
Atrioventricular block | 38.29 | 14.64 | 4 | 436669 | 7643 | 63044706 |
Gestational diabetes | 38.16 | 14.64 | 6 | 436667 | 8390 | 63043959 |
Joint arthroplasty | 38.09 | 14.64 | 68 | 436605 | 2673 | 63049676 |
Neck deformity | 38.03 | 14.64 | 59 | 436614 | 2062 | 63050287 |
Cholecystitis | 37.97 | 14.64 | 30 | 436643 | 15347 | 63037002 |
Posterior reversible encephalopathy syndrome | 37.83 | 14.64 | 38 | 436635 | 17307 | 63035042 |
Normal newborn | 37.83 | 14.64 | 6 | 436667 | 8335 | 63044014 |
Eructation | 37.78 | 14.64 | 6 | 436667 | 8327 | 63044022 |
Polyarthritis | 37.69 | 14.64 | 154 | 436519 | 9992 | 63042357 |
Blood loss anaemia | 37.54 | 14.64 | 8 | 436665 | 8993 | 63043356 |
White blood cell count increased | 37.41 | 14.64 | 189 | 436484 | 48372 | 63003977 |
Hypoacusis | 37.39 | 14.64 | 68 | 436605 | 24083 | 63028266 |
Mood altered | 37.38 | 14.64 | 28 | 436645 | 14715 | 63037634 |
Haemodialysis | 37.22 | 14.64 | 8 | 436665 | 8939 | 63043410 |
Extremity contracture | 37.08 | 14.64 | 45 | 436628 | 1240 | 63051109 |
Device malfunction | 36.84 | 14.64 | 41 | 436632 | 17816 | 63034533 |
Eyelid oedema | 36.81 | 14.64 | 13 | 436660 | 10466 | 63041883 |
Ovarian neoplasm | 36.69 | 14.64 | 38 | 436635 | 875 | 63051474 |
Prescribed underdose | 36.56 | 14.64 | 338 | 436335 | 29351 | 63022998 |
Infusion site extravasation | 36.51 | 14.64 | 13 | 436660 | 10413 | 63041936 |
Deep vein thrombosis postoperative | 36.42 | 14.64 | 165 | 436508 | 11204 | 63041145 |
Subarachnoid haemorrhage | 36.37 | 14.64 | 27 | 436646 | 14256 | 63038093 |
Pemphigoid | 36.37 | 14.64 | 4 | 436669 | 7340 | 63045009 |
Femur fracture | 36.22 | 14.64 | 443 | 436230 | 41313 | 63011036 |
Breast cancer stage I | 36.11 | 14.64 | 3 | 436670 | 6886 | 63045463 |
Epstein-Barr virus infection | 36.04 | 14.64 | 6 | 436667 | 8044 | 63044305 |
Underdose | 36.00 | 14.64 | 85 | 436588 | 27371 | 63024978 |
Chronic sinusitis | 35.76 | 14.64 | 22 | 436651 | 12821 | 63039528 |
Hair follicle tumour benign | 35.61 | 14.64 | 27 | 436646 | 404 | 63051945 |
Ear infection | 35.61 | 14.64 | 411 | 436262 | 37802 | 63014547 |
Mouth ulceration | 35.46 | 14.64 | 365 | 436308 | 32619 | 63019730 |
Heavy menstrual bleeding | 35.38 | 14.64 | 42 | 436631 | 17731 | 63034618 |
Bedridden | 35.11 | 14.64 | 160 | 436513 | 10891 | 63041458 |
Skin laceration | 35.10 | 14.64 | 64 | 436609 | 22644 | 63029705 |
Peripheral coldness | 35.05 | 14.64 | 20 | 436653 | 12145 | 63040204 |
Injection site swelling | 35.04 | 14.64 | 188 | 436485 | 47384 | 63004965 |
Soft tissue disorder | 34.86 | 14.64 | 87 | 436586 | 4335 | 63048014 |
End stage renal disease | 34.84 | 14.64 | 3 | 436670 | 6690 | 63045659 |
Colitis ulcerative | 34.83 | 14.64 | 80 | 436593 | 26011 | 63026338 |
Thyroid neoplasm | 34.81 | 14.64 | 82 | 436591 | 3937 | 63048412 |
Mean cell haemoglobin decreased | 34.80 | 14.64 | 96 | 436577 | 5083 | 63047266 |
Musculoskeletal chest pain | 34.79 | 14.64 | 57 | 436616 | 21026 | 63031323 |
Rhinorrhoea | 34.78 | 14.64 | 286 | 436387 | 65291 | 62987058 |
Cutaneous vasculitis | 34.75 | 14.64 | 97 | 436576 | 5172 | 63047177 |
Blood lactic acid increased | 34.74 | 14.64 | 4 | 436669 | 7082 | 63045267 |
Rib fracture | 34.65 | 14.64 | 64 | 436609 | 22533 | 63029816 |
Nocturia | 34.44 | 14.64 | 7 | 436666 | 8134 | 63044215 |
Myocarditis | 34.29 | 14.64 | 14 | 436659 | 10311 | 63042038 |
Allergic oedema | 34.25 | 14.64 | 35 | 436638 | 793 | 63051556 |
Eye pruritus | 34.18 | 14.64 | 47 | 436626 | 18624 | 63033725 |
Toxic encephalopathy | 34.11 | 14.64 | 3 | 436670 | 6576 | 63045773 |
Suspected suicide | 34.04 | 14.64 | 3 | 436670 | 6565 | 63045784 |
Upper-airway cough syndrome | 34.02 | 14.64 | 18 | 436655 | 11400 | 63040949 |
Lymphoedema | 34.01 | 14.64 | 19 | 436654 | 11673 | 63040676 |
Joint space narrowing | 33.99 | 14.64 | 30 | 436643 | 562 | 63051787 |
Immune thrombocytopenia | 33.95 | 14.64 | 15 | 436658 | 10541 | 63041808 |
Atrial septal defect | 33.81 | 14.64 | 4 | 436669 | 6934 | 63045415 |
Vascular device infection | 33.75 | 14.64 | 5 | 436668 | 7307 | 63045042 |
Lung neoplasm malignant | 33.42 | 14.64 | 52 | 436621 | 19581 | 63032768 |
Pustular psoriasis | 33.35 | 14.64 | 88 | 436585 | 4538 | 63047811 |
Delirium | 33.34 | 14.64 | 207 | 436466 | 50334 | 63002015 |
Acute coronary syndrome | 33.19 | 14.64 | 14 | 436659 | 10112 | 63042237 |
Walking aid user | 33.19 | 14.64 | 154 | 436519 | 10563 | 63041786 |
Haemolytic anaemia | 33.18 | 14.64 | 14 | 436659 | 10111 | 63042238 |
Hypoalbuminaemia | 33.18 | 14.64 | 20 | 436653 | 11785 | 63040564 |
Drug level decreased | 33.11 | 14.64 | 7 | 436666 | 7912 | 63044437 |
Hereditary angioedema | 33.06 | 14.64 | 6 | 436667 | 7556 | 63044793 |
Failure to thrive | 33.05 | 14.64 | 5 | 436668 | 7193 | 63045156 |
Generalised oedema | 32.99 | 14.64 | 36 | 436637 | 15782 | 63036567 |
Thinking abnormal | 32.88 | 14.64 | 16 | 436657 | 10627 | 63041722 |
Atrial flutter | 32.86 | 14.64 | 13 | 436660 | 9759 | 63042590 |
Mycobacterium tuberculosis complex test positive | 32.78 | 14.64 | 57 | 436616 | 2194 | 63050155 |
Hypoaesthesia oral | 32.72 | 14.64 | 25 | 436648 | 13008 | 63039341 |
Hypermobility syndrome | 32.62 | 14.64 | 34 | 436639 | 789 | 63051560 |
Blood triglycerides increased | 32.59 | 14.64 | 23 | 436650 | 12465 | 63039884 |
Acute pulmonary oedema | 32.53 | 14.64 | 8 | 436665 | 8150 | 63044199 |
Infiltration anaesthesia | 32.53 | 14.64 | 19 | 436654 | 178 | 63052171 |
Purpura | 32.40 | 14.64 | 19 | 436654 | 11366 | 63040983 |
Impaired gastric emptying | 32.39 | 14.64 | 149 | 436524 | 10183 | 63042166 |
Hiatus hernia | 32.37 | 14.64 | 62 | 436611 | 21532 | 63030817 |
Wound infection | 32.29 | 14.64 | 255 | 436418 | 21155 | 63031194 |
Unevaluable event | 32.09 | 14.64 | 214 | 436459 | 51172 | 63001177 |
Increased appetite | 32.07 | 14.64 | 13 | 436660 | 9617 | 63042732 |
Hemiplegia | 32.02 | 14.64 | 12 | 436661 | 9311 | 63043038 |
Neutrophil count increased | 31.90 | 14.64 | 40 | 436633 | 16487 | 63035862 |
Migraine | 31.87 | 14.64 | 509 | 436164 | 102837 | 62949512 |
Menstruation irregular | 31.85 | 14.64 | 5 | 436668 | 6999 | 63045350 |
Nystagmus | 31.81 | 14.64 | 3 | 436670 | 6217 | 63046132 |
Lymphadenopathy | 31.76 | 14.64 | 146 | 436527 | 38312 | 63014037 |
Dialysis | 31.72 | 14.64 | 16 | 436657 | 10411 | 63041938 |
Bradyphrenia | 31.70 | 14.64 | 5 | 436668 | 6975 | 63045374 |
Personality change | 31.66 | 14.64 | 5 | 436668 | 6968 | 63045381 |
Unintended pregnancy | 31.55 | 14.64 | 3 | 436670 | 6176 | 63046173 |
Rash papular | 31.37 | 14.64 | 37 | 436636 | 15665 | 63036684 |
Escherichia infection | 31.34 | 14.64 | 25 | 436648 | 12729 | 63039620 |
Skin papilloma | 31.33 | 14.64 | 90 | 436583 | 4879 | 63047470 |
Nephropathy toxic | 31.24 | 14.64 | 13 | 436660 | 9466 | 63042883 |
Drug tolerance | 31.18 | 14.64 | 112 | 436561 | 6837 | 63045512 |
Progressive multifocal leukoencephalopathy | 31.16 | 14.64 | 26 | 436647 | 12945 | 63039404 |
Labile blood pressure | 31.02 | 14.64 | 49 | 436624 | 1740 | 63050609 |
Lower limb fracture | 30.96 | 14.64 | 278 | 436395 | 23943 | 63028406 |
Female genital tract fistula | 30.96 | 14.64 | 7 | 436666 | 7552 | 63044797 |
Sensory disturbance | 30.93 | 14.64 | 29 | 436644 | 13643 | 63038706 |
Foetal growth restriction | 30.92 | 14.64 | 7 | 436666 | 7546 | 63044803 |
Taste disorder | 30.88 | 14.64 | 29 | 436644 | 13633 | 63038716 |
Alanine aminotransferase abnormal | 30.77 | 14.64 | 84 | 436589 | 4420 | 63047929 |
Pulmonary haemorrhage | 30.75 | 14.64 | 6 | 436667 | 7175 | 63045174 |
Skin reaction | 30.71 | 14.64 | 191 | 436482 | 14658 | 63037691 |
Nasal polyps | 30.65 | 14.64 | 3 | 436670 | 6036 | 63046313 |
Heart rate irregular | 30.54 | 14.64 | 68 | 436605 | 22353 | 63029996 |
Spinal compression fracture | 30.35 | 14.64 | 32 | 436641 | 14251 | 63038098 |
Pulmonary mass | 30.26 | 14.64 | 262 | 436411 | 22334 | 63030015 |
Weight increased | 30.20 | 14.64 | 2132 | 434541 | 258660 | 62793689 |
Cerebral ischaemia | 30.15 | 14.64 | 5 | 436668 | 6723 | 63045626 |
Prothrombin time prolonged | 30.12 | 14.64 | 14 | 436659 | 9550 | 63042799 |
Ageusia | 30.03 | 14.64 | 30 | 436643 | 13698 | 63038651 |
Needle issue | 29.98 | 14.64 | 17 | 436656 | 10359 | 63041990 |
Vasculitic rash | 29.86 | 14.64 | 42 | 436631 | 1342 | 63051007 |
Jaundice cholestatic | 29.56 | 14.64 | 7 | 436666 | 7317 | 63045032 |
Facet joint syndrome | 29.55 | 14.64 | 163 | 436510 | 11975 | 63040374 |
Cardiomyopathy | 29.53 | 14.64 | 47 | 436626 | 17537 | 63034812 |
Bipolar disorder | 29.50 | 14.64 | 9 | 436664 | 7951 | 63044398 |
Pre-existing condition improved | 29.35 | 14.64 | 10 | 436663 | 8234 | 63044115 |
Staphylococcal infection | 29.31 | 14.64 | 165 | 436508 | 41091 | 63011258 |
Haematocrit decreased | 29.24 | 14.64 | 155 | 436518 | 39185 | 63013164 |
Poor quality sleep | 29.22 | 14.64 | 58 | 436615 | 19877 | 63032472 |
Bacterial infection | 29.21 | 14.64 | 56 | 436617 | 19443 | 63032906 |
Cold sweat | 29.12 | 14.64 | 24 | 436649 | 12023 | 63040326 |
Product storage error | 29.08 | 14.64 | 36 | 436637 | 14920 | 63037429 |
Gastroenteritis viral | 29.02 | 14.64 | 76 | 436597 | 23624 | 63028725 |
Disease susceptibility | 29.01 | 14.64 | 18 | 436655 | 190 | 63052159 |
Secretion discharge | 28.95 | 14.64 | 163 | 436510 | 12068 | 63040281 |
Hepatitis cholestatic | 28.92 | 14.64 | 6 | 436667 | 6872 | 63045477 |
Interstitial lung disease | 28.92 | 14.64 | 592 | 436081 | 61316 | 62991033 |
Enterocolitis | 28.92 | 14.64 | 9 | 436664 | 7849 | 63044500 |
Mass excision | 28.75 | 14.64 | 22 | 436651 | 334 | 63052015 |
Psychomotor hyperactivity | 28.68 | 14.64 | 19 | 436654 | 10644 | 63041705 |
Sneezing | 28.46 | 14.64 | 51 | 436622 | 18167 | 63034182 |
Flank pain | 28.38 | 14.64 | 43 | 436630 | 16367 | 63035982 |
Granulocytopenia | 28.32 | 14.64 | 3 | 436670 | 5669 | 63046680 |
Injection site haemorrhage | 28.25 | 14.64 | 80 | 436593 | 24234 | 63028115 |
Live birth | 28.21 | 14.64 | 285 | 436388 | 25345 | 63027004 |
Angina unstable | 28.21 | 14.64 | 7 | 436666 | 7088 | 63045261 |
Apnoea | 28.10 | 14.64 | 10 | 436663 | 8012 | 63044337 |
Acute hepatic failure | 28.02 | 14.64 | 52 | 436621 | 18275 | 63034074 |
Brain injury | 27.90 | 14.64 | 7 | 436666 | 7036 | 63045313 |
Extra dose administered | 27.84 | 14.64 | 5 | 436668 | 6345 | 63046004 |
Spinal stenosis | 27.82 | 14.64 | 187 | 436486 | 14738 | 63037611 |
Immobile | 27.71 | 14.64 | 97 | 436576 | 5846 | 63046503 |
Drug-induced liver injury | 27.58 | 14.64 | 409 | 436264 | 39813 | 63012536 |
Acne | 27.54 | 14.64 | 76 | 436597 | 23217 | 63029132 |
Lipase increased | 27.51 | 14.64 | 17 | 436656 | 9883 | 63042466 |
Hypercalcaemia | 27.46 | 14.64 | 307 | 436366 | 28015 | 63024334 |
Eyelid ptosis | 27.33 | 14.64 | 8 | 436665 | 7259 | 63045090 |
Fistula | 27.31 | 14.64 | 19 | 436654 | 10374 | 63041975 |
Lupus vulgaris | 27.23 | 14.64 | 97 | 436576 | 5897 | 63046452 |
Glycosylated haemoglobin increased | 27.23 | 14.64 | 27 | 436646 | 12371 | 63039978 |
Exercise tolerance decreased | 27.21 | 14.64 | 3 | 436670 | 5494 | 63046855 |
Myocardial ischaemia | 27.11 | 14.64 | 29 | 436644 | 12830 | 63039519 |
Exposure during pregnancy | 27.06 | 14.64 | 1319 | 435354 | 154228 | 62898121 |
Arteriosclerosis coronary artery | 26.77 | 14.64 | 12 | 436661 | 8361 | 63043988 |
Functional gastrointestinal disorder | 26.71 | 14.64 | 77 | 436596 | 4182 | 63048167 |
Gait inability | 26.60 | 14.64 | 512 | 436161 | 52447 | 62999902 |
Insurance issue | 26.45 | 14.64 | 5 | 436668 | 6116 | 63046233 |
Hyperventilation | 26.42 | 14.64 | 5 | 436668 | 6111 | 63046238 |
Blood pressure systolic decreased | 26.29 | 14.64 | 9 | 436664 | 7388 | 63044961 |
Klebsiella infection | 26.27 | 14.64 | 13 | 436660 | 8553 | 63043796 |
Dry throat | 26.27 | 14.64 | 7 | 436666 | 6758 | 63045591 |
Drug resistance | 26.25 | 14.64 | 76 | 436597 | 22857 | 63029492 |
Erythema multiforme | 26.18 | 14.64 | 19 | 436654 | 10150 | 63042199 |
Hepatic enzyme abnormal | 26.15 | 14.64 | 100 | 436573 | 6292 | 63046057 |
Proteinuria | 26.13 | 14.64 | 58 | 436615 | 19087 | 63033262 |
Wrist fracture | 26.10 | 14.64 | 33 | 436640 | 13554 | 63038795 |
Salivary hypersecretion | 26.10 | 14.64 | 10 | 436663 | 7656 | 63044693 |
Menstrual disorder | 26.04 | 14.64 | 3 | 436670 | 5310 | 63047039 |
Intermenstrual bleeding | 25.91 | 14.64 | 11 | 436662 | 7915 | 63044434 |
Oligohydramnios | 25.86 | 14.64 | 6 | 436667 | 6360 | 63045989 |
Bone disorder | 25.86 | 14.64 | 242 | 436431 | 21084 | 63031265 |
Metastases to lymph nodes | 25.60 | 14.64 | 12 | 436661 | 8146 | 63044203 |
Concussion | 25.51 | 14.64 | 16 | 436657 | 9228 | 63043121 |
Intracranial pressure increased | 25.50 | 14.64 | 3 | 436670 | 5224 | 63047125 |
Skin irritation | 25.34 | 14.64 | 18 | 436655 | 9723 | 63042626 |
Motor dysfunction | 25.33 | 14.64 | 22 | 436651 | 10739 | 63041610 |
Metastasis | 25.31 | 14.64 | 3 | 436670 | 5194 | 63047155 |
Anger | 25.26 | 14.64 | 29 | 436644 | 12427 | 63039922 |
Eczema | 25.26 | 14.64 | 125 | 436548 | 32166 | 63020183 |
Mean cell haemoglobin concentration abnormal | 25.21 | 14.64 | 14 | 436659 | 118 | 63052231 |
Allergy to chemicals | 25.20 | 14.64 | 61 | 436612 | 2981 | 63049368 |
Injection site reaction | 25.19 | 14.64 | 553 | 436120 | 57971 | 62994378 |
Foetal death | 25.18 | 14.64 | 23 | 436650 | 10957 | 63041392 |
Rheumatoid factor | 25.16 | 14.64 | 20 | 436653 | 322 | 63052027 |
Refusal of treatment by patient | 24.82 | 14.64 | 4 | 436669 | 5493 | 63046856 |
Pain of skin | 24.79 | 14.64 | 26 | 436647 | 11608 | 63040741 |
Ankle deformity | 24.79 | 14.64 | 23 | 436650 | 461 | 63051888 |
Enteritis | 24.78 | 14.64 | 13 | 436660 | 8273 | 63044076 |
Asphyxia | 24.77 | 14.64 | 6 | 436667 | 6175 | 63046174 |
Metabolic disorder | 24.75 | 14.64 | 7 | 436666 | 6496 | 63045853 |
Intestinal sepsis | 24.58 | 14.64 | 19 | 436654 | 293 | 63052056 |
Pneumonia fungal | 24.57 | 14.64 | 4 | 436669 | 5451 | 63046898 |
Dizziness postural | 24.49 | 14.64 | 10 | 436663 | 7366 | 63044983 |
Petechiae | 24.43 | 14.64 | 36 | 436637 | 13861 | 63038488 |
Vitamin D deficiency | 24.41 | 14.64 | 36 | 436637 | 13856 | 63038493 |
Bundle branch block left | 24.39 | 14.64 | 9 | 436664 | 7050 | 63045299 |
Large intestine perforation | 24.36 | 14.64 | 14 | 436659 | 8468 | 63043881 |
Lip dry | 24.30 | 14.64 | 186 | 436487 | 15284 | 63037065 |
Blood albumin decreased | 24.29 | 14.64 | 40 | 436633 | 14726 | 63037623 |
Respiration abnormal | 24.25 | 14.64 | 7 | 436666 | 6410 | 63045939 |
Ear discomfort | 24.25 | 14.64 | 12 | 436661 | 7894 | 63044455 |
Injection site hypersensitivity | 24.14 | 14.64 | 48 | 436625 | 2049 | 63050300 |
Gingival pain | 24.12 | 14.64 | 13 | 436660 | 8149 | 63044200 |
Localised oedema | 24.09 | 14.64 | 4 | 436669 | 5374 | 63046975 |
Infusion site pruritus | 23.91 | 14.64 | 6 | 436667 | 6029 | 63046320 |
Osteoporotic fracture | 23.76 | 14.64 | 68 | 436605 | 3678 | 63048671 |
Rheumatic disorder | 23.75 | 14.64 | 60 | 436613 | 3012 | 63049337 |
Hyperthermia | 23.72 | 14.64 | 17 | 436656 | 9139 | 63043210 |
Therapy partial responder | 23.65 | 14.64 | 23 | 436650 | 10635 | 63041714 |
Spinal fracture | 23.61 | 14.64 | 57 | 436616 | 18214 | 63034135 |
Tumour marker increased | 23.54 | 14.64 | 3 | 436670 | 4912 | 63047437 |
Systemic inflammatory response syndrome | 23.44 | 14.64 | 5 | 436668 | 5616 | 63046733 |
Bowel movement irregularity | 23.40 | 14.64 | 4 | 436669 | 5260 | 63047089 |
White blood cell count abnormal | 23.39 | 14.64 | 95 | 436578 | 6147 | 63046202 |
Glucose tolerance impaired | 23.38 | 14.64 | 8 | 436665 | 6569 | 63045780 |
Oral discomfort | 23.37 | 14.64 | 125 | 436548 | 9076 | 63043273 |
Major depression | 23.36 | 14.64 | 13 | 436660 | 8005 | 63044344 |
Peritonitis bacterial | 23.32 | 14.64 | 3 | 436670 | 4876 | 63047473 |
Fungal infection | 23.30 | 14.64 | 153 | 436520 | 36721 | 63015628 |
Hypovolaemic shock | 23.23 | 14.64 | 7 | 436666 | 6234 | 63046115 |
Diabetic eye disease | 23.20 | 14.64 | 14 | 436659 | 140 | 63052209 |
Arteriosclerosis | 23.18 | 14.64 | 21 | 436652 | 10045 | 63042304 |
Eye movement disorder | 23.18 | 14.64 | 4 | 436669 | 5224 | 63047125 |
Colitis microscopic | 23.13 | 14.64 | 126 | 436547 | 9213 | 63043136 |
Heart rate decreased | 23.12 | 14.64 | 201 | 436472 | 45359 | 63006990 |
Brain natriuretic peptide increased | 23.08 | 14.64 | 4 | 436669 | 5209 | 63047140 |
Appendicitis | 23.04 | 14.64 | 14 | 436659 | 8215 | 63044134 |
Lung infiltration | 23.04 | 14.64 | 40 | 436633 | 14423 | 63037926 |
C-reactive protein | 23.03 | 14.64 | 80 | 436593 | 4802 | 63047547 |
Nail disorder | 23.03 | 14.64 | 161 | 436512 | 12854 | 63039495 |
Cardiac failure acute | 22.99 | 14.64 | 19 | 436654 | 9504 | 63042845 |
Device leakage | 22.96 | 14.64 | 10 | 436663 | 7086 | 63045263 |
Drug use disorder | 22.93 | 14.64 | 81 | 436592 | 4903 | 63047446 |
Expired product administered | 22.89 | 14.64 | 7 | 436666 | 6174 | 63046175 |
Hepatic fibrosis | 22.88 | 14.64 | 66 | 436607 | 3586 | 63048763 |
Pelvic pain | 22.83 | 14.64 | 36 | 436637 | 13483 | 63038866 |
Steatohepatitis | 22.79 | 14.64 | 25 | 436648 | 616 | 63051733 |
Diastolic dysfunction | 22.78 | 14.64 | 8 | 436665 | 6463 | 63045886 |
Embolism | 22.78 | 14.64 | 13 | 436660 | 7893 | 63044456 |
Fracture delayed union | 22.72 | 14.64 | 51 | 436622 | 2371 | 63049978 |
Product complaint | 22.70 | 14.64 | 33 | 436640 | 12776 | 63039573 |
Sudden death | 22.67 | 14.64 | 23 | 436650 | 10426 | 63041923 |
Splenomegaly | 22.60 | 14.64 | 26 | 436647 | 11131 | 63041218 |
Scleroderma | 22.49 | 14.64 | 5 | 436668 | 5457 | 63046892 |
Pneumothorax | 22.41 | 14.64 | 49 | 436624 | 16212 | 63036137 |
Bronchopulmonary aspergillosis | 22.41 | 14.64 | 16 | 436657 | 8619 | 63043730 |
Post procedural complication | 22.27 | 14.64 | 53 | 436620 | 17021 | 63035328 |
Concomitant disease aggravated | 22.22 | 14.64 | 18 | 436655 | 9094 | 63043255 |
Blood potassium increased | 22.20 | 14.64 | 59 | 436614 | 18250 | 63034099 |
Micturition urgency | 22.20 | 14.64 | 20 | 436653 | 9591 | 63042758 |
Polyomavirus-associated nephropathy | 22.12 | 14.64 | 43 | 436630 | 1805 | 63050544 |
Hepatic ischaemia | 22.07 | 14.64 | 25 | 436648 | 639 | 63051710 |
Blood alkaline phosphatase increased | 22.05 | 14.64 | 189 | 436484 | 42778 | 63009571 |
Middle lobe syndrome | 22.04 | 14.64 | 9 | 436664 | 34 | 63052315 |
Activated partial thromboplastin time prolonged | 21.85 | 14.64 | 10 | 436663 | 6883 | 63045466 |
Cholecystitis acute | 21.84 | 14.64 | 15 | 436658 | 8245 | 63044104 |
Hypertonia | 21.80 | 14.64 | 3 | 436670 | 4634 | 63047715 |
Aortic valve incompetence | 21.78 | 14.64 | 7 | 436666 | 5981 | 63046368 |
Juvenile idiopathic arthritis | 21.71 | 14.64 | 61 | 436612 | 3265 | 63049084 |
Red blood cell count decreased | 21.67 | 14.64 | 177 | 436496 | 40468 | 63011881 |
Vitreous floaters | 21.66 | 14.64 | 7 | 436666 | 5959 | 63046390 |
Upper limb fracture | 21.61 | 14.64 | 63 | 436610 | 18905 | 63033444 |
Hypertriglyceridaemia | 21.59 | 14.64 | 8 | 436665 | 6251 | 63046098 |
Eye irritation | 21.54 | 14.64 | 78 | 436595 | 21893 | 63030456 |
Enthesophyte | 21.52 | 14.64 | 10 | 436663 | 55 | 63052294 |
Supraventricular extrasystoles | 21.50 | 14.64 | 3 | 436670 | 4586 | 63047763 |
Bronchospasm | 21.48 | 14.64 | 55 | 436618 | 17225 | 63035124 |
Rales | 21.26 | 14.64 | 34 | 436639 | 12663 | 63039686 |
Osteomyelitis | 21.26 | 14.64 | 273 | 436400 | 25747 | 63026602 |
Bladder cancer | 21.16 | 14.64 | 6 | 436667 | 5560 | 63046789 |
Congestive cardiomyopathy | 21.16 | 14.64 | 8 | 436665 | 6174 | 63046175 |
Laboratory test abnormal | 21.15 | 14.64 | 104 | 436569 | 26808 | 63025541 |
Hyperammonaemia | 21.12 | 14.64 | 5 | 436668 | 5227 | 63047122 |
Stillbirth | 21.08 | 14.64 | 10 | 436663 | 6740 | 63045609 |
Peripheral venous disease | 21.01 | 14.64 | 180 | 436493 | 15297 | 63037052 |
Facial pain | 20.98 | 14.64 | 25 | 436648 | 10536 | 63041813 |
Lung disorder | 20.98 | 14.64 | 569 | 436104 | 61692 | 62990657 |
Inflammatory marker increased | 20.97 | 14.64 | 98 | 436575 | 6741 | 63045608 |
Drug level below therapeutic | 20.97 | 14.64 | 4 | 436669 | 4862 | 63047487 |
International normalised ratio decreased | 20.96 | 14.64 | 3 | 436670 | 4498 | 63047851 |
Dental caries | 20.90 | 14.64 | 26 | 436647 | 10753 | 63041596 |
Spinal meningioma benign | 20.86 | 14.64 | 12 | 436661 | 109 | 63052240 |
Rash maculo-papular | 20.84 | 14.64 | 131 | 436542 | 31765 | 63020584 |
Pain in extremity | 20.82 | 14.64 | 2594 | 434079 | 328892 | 62723457 |
Polycystic ovaries | 20.77 | 14.64 | 3 | 436670 | 4468 | 63047881 |
Pseudomonas infection | 20.76 | 14.64 | 28 | 436645 | 11185 | 63041164 |
Internal haemorrhage | 20.72 | 14.64 | 5 | 436668 | 5160 | 63047189 |
Hepatomegaly | 20.71 | 14.64 | 31 | 436642 | 11858 | 63040491 |
Extrasystoles | 20.69 | 14.64 | 5 | 436668 | 5155 | 63047194 |
Breast pain | 20.69 | 14.64 | 18 | 436655 | 8780 | 63043569 |
Drug level above therapeutic | 20.60 | 14.64 | 4 | 436669 | 4801 | 63047548 |
Neck mass | 20.57 | 14.64 | 63 | 436610 | 3540 | 63048809 |
Affect lability | 20.49 | 14.64 | 28 | 436645 | 11123 | 63041226 |
Accident | 20.42 | 14.64 | 89 | 436584 | 5943 | 63046406 |
Breast cancer female | 20.26 | 14.64 | 39 | 436634 | 13520 | 63038829 |
Arthritis bacterial | 20.11 | 14.64 | 93 | 436580 | 6370 | 63045979 |
Sleep disorder due to a general medical condition | 20.07 | 14.64 | 33 | 436640 | 12155 | 63040194 |
Sinus congestion | 20.06 | 14.64 | 61 | 436612 | 18062 | 63034287 |
Hepatic cirrhosis | 19.99 | 14.64 | 259 | 436414 | 24475 | 63027874 |
Abscess | 19.99 | 14.64 | 54 | 436619 | 16614 | 63035735 |
Orthopnoea | 19.98 | 14.64 | 9 | 436664 | 6252 | 63046097 |
Urine analysis abnormal | 19.84 | 14.64 | 5 | 436668 | 5011 | 63047338 |
Photophobia | 19.78 | 14.64 | 59 | 436614 | 17576 | 63034773 |
Enterococcal infection | 19.77 | 14.64 | 15 | 436658 | 7833 | 63044516 |
Loss of employment | 19.67 | 14.64 | 46 | 436627 | 2198 | 63050151 |
Gastroenteritis | 19.63 | 14.64 | 105 | 436568 | 26485 | 63025864 |
Forced expiratory volume decreased | 19.56 | 14.64 | 5 | 436668 | 4963 | 63047386 |
SARS-CoV-2 test positive | 19.54 | 14.64 | 16 | 436657 | 8040 | 63044309 |
Heart rate abnormal | 19.44 | 14.64 | 5 | 436668 | 4942 | 63047407 |
Lyme disease | 19.40 | 14.64 | 60 | 436613 | 3389 | 63048960 |
Maternal exposure during breast feeding | 19.35 | 14.64 | 3 | 436670 | 4238 | 63048111 |
Invasive ductal breast carcinoma | 19.26 | 14.64 | 12 | 436661 | 6946 | 63045403 |
Maternal exposure timing unspecified | 19.19 | 14.64 | 98 | 436575 | 6989 | 63045360 |
Snoring | 19.11 | 14.64 | 3 | 436670 | 4199 | 63048150 |
Ileus paralytic | 19.07 | 14.64 | 4 | 436669 | 4547 | 63047802 |
Paralysis | 19.07 | 14.64 | 24 | 436649 | 9876 | 63042473 |
Thrombotic microangiopathy | 18.92 | 14.64 | 27 | 436646 | 10534 | 63041815 |
Respiratory rate increased | 18.91 | 14.64 | 41 | 436632 | 13607 | 63038742 |
Abnormal faeces | 18.91 | 14.64 | 7 | 436666 | 5473 | 63046876 |
Transplant rejection | 18.88 | 14.64 | 28 | 436645 | 10752 | 63041597 |
Photopsia | 18.82 | 14.64 | 4 | 436669 | 4505 | 63047844 |
Treatment noncompliance | 18.79 | 14.64 | 165 | 436508 | 37160 | 63015189 |
Spinal cord compression | 18.77 | 14.64 | 3 | 436670 | 4145 | 63048204 |
Cellulitis gangrenous | 18.74 | 14.64 | 9 | 436664 | 54 | 63052295 |
Oral mucosal blistering | 18.67 | 14.64 | 8 | 436665 | 5725 | 63046624 |
Scratch | 18.62 | 14.64 | 11 | 436662 | 6554 | 63045795 |
Osteonecrosis | 18.59 | 14.64 | 96 | 436577 | 24434 | 63027915 |
Drug dose omission by device | 18.58 | 14.64 | 5 | 436668 | 4796 | 63047553 |
Bursitis | 18.57 | 14.64 | 358 | 436315 | 36683 | 63015666 |
Cardiac tamponade | 18.43 | 14.64 | 5 | 436668 | 4770 | 63047579 |
Polyp | 18.39 | 14.64 | 11 | 436662 | 6510 | 63045839 |
Diverticulum | 18.35 | 14.64 | 34 | 436639 | 11957 | 63040392 |
Injection site bruising | 18.25 | 14.64 | 192 | 436481 | 41718 | 63010631 |
Blood culture positive | 18.20 | 14.64 | 5 | 436668 | 4730 | 63047619 |
Dermatitis bullous | 18.15 | 14.64 | 19 | 436654 | 8489 | 63043860 |
Limb injury | 18.04 | 14.64 | 102 | 436571 | 25375 | 63026974 |
Ketoacidosis | 18.04 | 14.64 | 4 | 436669 | 4374 | 63047975 |
Ventricular septal defect | 18.04 | 14.64 | 4 | 436669 | 4374 | 63047975 |
Premature rupture of membranes | 17.88 | 14.64 | 6 | 436667 | 4987 | 63047362 |
Blood thyroid stimulating hormone increased | 17.81 | 14.64 | 14 | 436659 | 7180 | 63045169 |
Aphonia | 17.76 | 14.64 | 26 | 436647 | 10037 | 63042312 |
Facial bones fracture | 17.75 | 14.64 | 3 | 436670 | 3979 | 63048370 |
Product residue present | 17.74 | 14.64 | 3 | 436670 | 3976 | 63048373 |
Overwork | 17.71 | 14.64 | 9 | 436664 | 62 | 63052287 |
Arteriospasm coronary | 17.67 | 14.64 | 3 | 436670 | 3965 | 63048384 |
Cytomegalovirus infection reactivation | 17.64 | 14.64 | 3 | 436670 | 3960 | 63048389 |
Maternal drugs affecting foetus | 17.58 | 14.64 | 7 | 436666 | 5235 | 63047114 |
Blood glucose abnormal | 17.55 | 14.64 | 17 | 436656 | 7875 | 63044474 |
Ocular toxicity | 17.53 | 14.64 | 23 | 436650 | 687 | 63051662 |
Haemorrhagic stroke | 17.45 | 14.64 | 9 | 436664 | 5783 | 63046566 |
Catheterisation cardiac | 17.43 | 14.64 | 5 | 436668 | 4598 | 63047751 |
Anosmia | 17.43 | 14.64 | 13 | 436660 | 6847 | 63045502 |
Tendonitis | 17.40 | 14.64 | 209 | 436464 | 19406 | 63032943 |
Bunion operation | 17.36 | 14.64 | 32 | 436641 | 1290 | 63051059 |
Tongue oedema | 17.33 | 14.64 | 5 | 436668 | 4581 | 63047768 |
Limb operation | 17.27 | 14.64 | 64 | 436609 | 3967 | 63048382 |
Localised infection | 17.25 | 14.64 | 298 | 436375 | 29912 | 63022437 |
Visual field defect | 17.23 | 14.64 | 12 | 436661 | 6549 | 63045800 |
Oxygen consumption increased | 17.16 | 14.64 | 3 | 436670 | 3881 | 63048468 |
Clear cell renal cell carcinoma | 17.10 | 14.64 | 34 | 436639 | 1451 | 63050898 |
COVID-19 pneumonia | 17.07 | 14.64 | 46 | 436627 | 14163 | 63038186 |
Parotid gland enlargement | 16.99 | 14.64 | 25 | 436648 | 833 | 63051516 |
Choking | 16.97 | 14.64 | 26 | 436647 | 9853 | 63042496 |
Colon cancer | 16.97 | 14.64 | 26 | 436647 | 9852 | 63042497 |
Urine abnormality | 16.95 | 14.64 | 14 | 436659 | 7005 | 63045344 |
Bladder disorder | 16.91 | 14.64 | 22 | 436651 | 8924 | 63043425 |
Hepatic necrosis | 16.89 | 14.64 | 9 | 436664 | 5678 | 63046671 |
Arterial occlusive disease | 16.88 | 14.64 | 10 | 436663 | 5948 | 63046401 |
Infusion site bruising | 16.84 | 14.64 | 3 | 436670 | 3829 | 63048520 |
Infusion site haemorrhage | 16.72 | 14.64 | 7 | 436666 | 5079 | 63047270 |
Sputum discoloured | 16.72 | 14.64 | 57 | 436616 | 16290 | 63036059 |
Tooth extraction | 16.70 | 14.64 | 28 | 436645 | 10236 | 63042113 |
Diffuse large B-cell lymphoma | 16.69 | 14.64 | 13 | 436660 | 6699 | 63045650 |
Feeling drunk | 16.64 | 14.64 | 4 | 436669 | 4138 | 63048211 |
Muscle relaxant therapy | 16.56 | 14.64 | 12 | 436661 | 167 | 63052182 |
Breast mass | 16.55 | 14.64 | 18 | 436655 | 7904 | 63044445 |
Large intestine polyp | 16.53 | 14.64 | 19 | 436654 | 8138 | 63044211 |
Hydronephrosis | 16.52 | 14.64 | 30 | 436643 | 10632 | 63041717 |
Gingival swelling | 16.37 | 14.64 | 5 | 436668 | 4413 | 63047936 |
Amyotrophic lateral sclerosis | 16.35 | 14.64 | 29 | 436644 | 1134 | 63051215 |
Device occlusion | 16.32 | 14.64 | 16 | 436657 | 7371 | 63044978 |
Neutrophilia | 16.30 | 14.64 | 5 | 436668 | 4401 | 63047948 |
Skin burning sensation | 16.24 | 14.64 | 40 | 436633 | 12694 | 63039655 |
Sluggishness | 16.16 | 14.64 | 8 | 436665 | 5261 | 63047088 |
Anxiety disorder | 16.09 | 14.64 | 4 | 436669 | 4046 | 63048303 |
Retinal haemorrhage | 16.08 | 14.64 | 7 | 436666 | 4962 | 63047387 |
Thrombophlebitis | 16.08 | 14.64 | 5 | 436668 | 4363 | 63047986 |
Spinal fusion surgery | 16.07 | 14.64 | 79 | 436594 | 5549 | 63046800 |
Sexual dysfunction | 16.03 | 14.64 | 5 | 436668 | 4354 | 63047995 |
Ammonia increased | 15.98 | 14.64 | 6 | 436667 | 4650 | 63047699 |
Culture urine positive | 15.96 | 14.64 | 3 | 436670 | 3684 | 63048665 |
Breast cancer recurrent | 15.92 | 14.64 | 5 | 436668 | 4336 | 63048013 |
Middle insomnia | 15.90 | 14.64 | 40 | 436633 | 12603 | 63039746 |
Brain herniation | 15.90 | 14.64 | 3 | 436670 | 3674 | 63048675 |
Pyelonephritis acute | 15.89 | 14.64 | 6 | 436667 | 4635 | 63047714 |
Gallbladder disorder | 15.88 | 14.64 | 71 | 436602 | 18771 | 63033578 |
Intervertebral disc space narrowing | 15.79 | 14.64 | 27 | 436646 | 1025 | 63051324 |
Skin tightness | 15.78 | 14.64 | 5 | 436668 | 4311 | 63048038 |
Catheter site infection | 15.78 | 14.64 | 7 | 436666 | 4907 | 63047442 |
Humerus fracture | 15.77 | 14.64 | 23 | 436650 | 8893 | 63043456 |
Facial paralysis | 15.73 | 14.64 | 47 | 436626 | 13994 | 63038355 |
Multiple drug therapy | 15.71 | 14.64 | 3 | 436670 | 3643 | 63048706 |
Dermatitis exfoliative | 15.69 | 14.64 | 9 | 436664 | 5450 | 63046899 |
Formication | 15.64 | 14.64 | 5 | 436668 | 4286 | 63048063 |
Hyperpyrexia | 15.62 | 14.64 | 3 | 436670 | 3629 | 63048720 |
Drug screen positive | 15.61 | 14.64 | 3 | 436670 | 3626 | 63048723 |
Left ventricular failure | 15.48 | 14.64 | 10 | 436663 | 5677 | 63046672 |
Pelvic fracture | 15.45 | 14.64 | 44 | 436629 | 13304 | 63039045 |
Tongue disorder | 15.40 | 14.64 | 125 | 436548 | 10455 | 63041894 |
Hair texture abnormal | 15.36 | 14.64 | 5 | 436668 | 4238 | 63048111 |
Lip oedema | 15.35 | 14.64 | 4 | 436669 | 3920 | 63048429 |
Polydipsia | 15.21 | 14.64 | 3 | 436670 | 3561 | 63048788 |
Product monitoring error | 15.20 | 14.64 | 6 | 436667 | 4510 | 63047839 |
Aspergillus infection | 15.19 | 14.64 | 20 | 436653 | 8073 | 63044276 |
Pharyngeal swelling | 15.18 | 14.64 | 13 | 436660 | 6391 | 63045958 |
Impaired driving ability | 15.17 | 14.64 | 6 | 436667 | 4505 | 63047844 |
Injury | 15.10 | 14.64 | 632 | 436041 | 72615 | 62979734 |
Uterine leiomyoma | 15.05 | 14.64 | 25 | 436648 | 9173 | 63043176 |
Gangrene | 15.05 | 14.64 | 12 | 436661 | 6111 | 63046238 |
Aplasia pure red cell | 15.04 | 14.64 | 6 | 436667 | 4481 | 63047868 |
Hepatic cancer | 15.04 | 14.64 | 6 | 436667 | 4481 | 63047868 |
Neoplasm | 15.01 | 14.64 | 17 | 436656 | 7328 | 63045021 |
Dysaesthesia | 14.99 | 14.64 | 6 | 436667 | 4472 | 63047877 |
Soft tissue swelling | 14.96 | 14.64 | 29 | 436644 | 1215 | 63051134 |
Trigeminal neuralgia | 14.94 | 14.64 | 3 | 436670 | 3516 | 63048833 |
Renal pain | 14.92 | 14.64 | 14 | 436659 | 6585 | 63045764 |
Fibrin D dimer increased | 14.90 | 14.64 | 8 | 436665 | 5026 | 63047323 |
Bacterial test positive | 14.90 | 14.64 | 9 | 436664 | 5298 | 63047051 |
Stridor | 14.89 | 14.64 | 3 | 436670 | 3507 | 63048842 |
Hydrocephalus | 14.87 | 14.64 | 9 | 436664 | 5291 | 63047058 |
Galactorrhoea | 14.86 | 14.64 | 5 | 436668 | 4150 | 63048199 |
Coronary artery stenosis | 14.86 | 14.64 | 7 | 436666 | 4737 | 63047612 |
Paradoxical drug reaction | 14.85 | 14.64 | 5 | 436668 | 4147 | 63048202 |
Salt craving | 14.83 | 14.64 | 10 | 436663 | 123 | 63052226 |
Abdominal hernia | 14.79 | 14.64 | 8 | 436665 | 5004 | 63047345 |
Atypical pneumonia | 14.78 | 14.64 | 6 | 436667 | 4434 | 63047915 |
Gastrointestinal perforation | 14.77 | 14.64 | 3 | 436670 | 3488 | 63048861 |
Nail psoriasis | 14.65 | 14.64 | 20 | 436653 | 621 | 63051728 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug ineffective | 2271.41 | 15.57 | 3421 | 60985 | 453330 | 34439195 |
Rheumatoid arthritis | 1754.08 | 15.57 | 1009 | 63397 | 37229 | 34855296 |
Joint swelling | 1666.66 | 15.57 | 1151 | 63255 | 58739 | 34833786 |
Drug intolerance | 1527.26 | 15.57 | 1089 | 63317 | 58481 | 34834044 |
Contraindicated product administered | 931.11 | 15.57 | 547 | 63859 | 20934 | 34871591 |
Synovitis | 796.59 | 15.57 | 427 | 63979 | 13639 | 34878886 |
Treatment failure | 775.38 | 15.57 | 661 | 63745 | 46036 | 34846489 |
C-reactive protein abnormal | 711.96 | 15.57 | 339 | 64067 | 8371 | 34884154 |
Arthralgia | 611.12 | 15.57 | 1109 | 63297 | 168932 | 34723593 |
Apparent death | 607.64 | 15.57 | 235 | 64171 | 3409 | 34889116 |
Arthropathy | 591.21 | 15.57 | 449 | 63957 | 26458 | 34866067 |
Musculoskeletal stiffness | 567.55 | 15.57 | 555 | 63851 | 46125 | 34846400 |
Therapeutic product effect decreased | 528.32 | 15.57 | 468 | 63938 | 34275 | 34858250 |
Bone erosion | 527.32 | 15.57 | 218 | 64188 | 3797 | 34888728 |
Pain | 525.36 | 15.57 | 1160 | 63246 | 203515 | 34689010 |
Red blood cell sedimentation rate abnormal | 454.91 | 15.57 | 190 | 64216 | 3399 | 34889126 |
Diverticulitis | 435.31 | 15.57 | 332 | 64074 | 19672 | 34872853 |
Psoriatic arthropathy | 425.14 | 15.57 | 326 | 64080 | 19472 | 34873053 |
Drug hypersensitivity | 408.12 | 15.57 | 614 | 63792 | 79915 | 34812610 |
Drug eruption | 330.47 | 15.57 | 282 | 64124 | 19616 | 34872909 |
Mobility decreased | 321.51 | 15.57 | 334 | 64072 | 29794 | 34862731 |
Loss of personal independence in daily activities | 319.01 | 15.57 | 348 | 64058 | 32831 | 34859694 |
Hand deformity | 310.46 | 15.57 | 147 | 64259 | 3578 | 34888947 |
Urticaria | 307.88 | 15.57 | 470 | 63936 | 61907 | 34830618 |
Pain in extremity | 297.93 | 15.57 | 694 | 63712 | 125819 | 34766706 |
Stomatitis | 286.57 | 15.57 | 372 | 64034 | 42142 | 34850383 |
Red blood cell sedimentation rate increased | 284.66 | 15.57 | 189 | 64217 | 8973 | 34883552 |
C-reactive protein increased | 284.59 | 15.57 | 420 | 63986 | 53678 | 34838847 |
Death | 273.13 | 15.57 | 202 | 64204 | 397847 | 34494678 |
Arthritis | 229.71 | 15.57 | 286 | 64120 | 31060 | 34861465 |
Hypotension | 228.56 | 15.57 | 63 | 64343 | 221586 | 34670939 |
Hypersensitivity | 223.22 | 15.57 | 402 | 64004 | 60633 | 34831892 |
Sleep disorder due to general medical condition, insomnia type | 219.82 | 15.57 | 85 | 64321 | 1231 | 34891294 |
Febrile neutropenia | 217.00 | 15.57 | 8 | 64398 | 136841 | 34755684 |
Disability | 215.88 | 15.57 | 125 | 64281 | 4640 | 34887885 |
Therapeutic product effect incomplete | 203.08 | 15.57 | 347 | 64059 | 50194 | 34842331 |
Acute kidney injury | 197.19 | 15.57 | 164 | 64242 | 304824 | 34587701 |
Rheumatoid nodule | 191.02 | 15.57 | 98 | 64308 | 2849 | 34889676 |
Rheumatoid factor negative | 190.03 | 15.57 | 69 | 64337 | 830 | 34891695 |
Alanine aminotransferase abnormal | 183.71 | 15.57 | 112 | 64294 | 4576 | 34887949 |
Limb discomfort | 182.21 | 15.57 | 156 | 64250 | 10891 | 34881634 |
Osteoarthritis | 178.59 | 15.57 | 205 | 64201 | 20437 | 34872088 |
Impaired work ability | 177.62 | 15.57 | 127 | 64279 | 6803 | 34885722 |
Anti-cyclic citrullinated peptide antibody positive | 176.21 | 15.57 | 80 | 64326 | 1763 | 34890762 |
Anaemia | 170.77 | 15.57 | 110 | 64296 | 233225 | 34659300 |
Peripheral swelling | 170.23 | 15.57 | 411 | 63995 | 76130 | 34816395 |
Knee arthroplasty | 169.48 | 15.57 | 127 | 64279 | 7317 | 34885208 |
Pulmonary thrombosis | 163.38 | 15.57 | 124 | 64282 | 7283 | 34885242 |
Toxicity to various agents | 161.44 | 15.57 | 84 | 64322 | 200278 | 34692247 |
Chondropathy | 159.70 | 15.57 | 62 | 64344 | 908 | 34891617 |
Confusional state | 158.07 | 15.57 | 36 | 64370 | 144124 | 34748401 |
Bone cyst | 157.88 | 15.57 | 71 | 64335 | 1529 | 34890996 |
Tenosynovitis | 153.47 | 15.57 | 99 | 64307 | 4471 | 34888054 |
Gastrointestinal disorder | 150.95 | 15.57 | 244 | 64162 | 33704 | 34858821 |
Swelling | 150.94 | 15.57 | 276 | 64130 | 42090 | 34850435 |
Enthesopathy | 150.17 | 15.57 | 98 | 64308 | 4515 | 34888010 |
Drug tolerance decreased | 149.87 | 15.57 | 73 | 64333 | 1894 | 34890631 |
Drug interaction | 147.71 | 15.57 | 120 | 64286 | 225826 | 34666699 |
Malignant neoplasm progression | 143.60 | 15.57 | 4 | 64402 | 88042 | 34804483 |
Lymphoma | 143.03 | 15.57 | 144 | 64262 | 12363 | 34880162 |
Constipation | 140.91 | 15.57 | 39 | 64367 | 136943 | 34755582 |
Terminal state | 139.00 | 15.57 | 88 | 64318 | 3846 | 34888679 |
Onychoclasis | 137.26 | 15.57 | 68 | 64338 | 1832 | 34890693 |
Joint ankylosis | 130.87 | 15.57 | 62 | 64344 | 1510 | 34891015 |
Dehydration | 128.19 | 15.57 | 40 | 64366 | 129929 | 34762596 |
Atlantoaxial instability | 126.33 | 15.57 | 40 | 64366 | 305 | 34892220 |
Hepatic function abnormal | 125.18 | 15.57 | 262 | 64144 | 44101 | 34848424 |
Thrombocytopenia | 125.05 | 15.57 | 66 | 64340 | 156181 | 34736344 |
Herpes zoster | 124.92 | 15.57 | 226 | 64180 | 34173 | 34858352 |
Spinal instability | 124.11 | 15.57 | 40 | 64366 | 325 | 34892200 |
Mineral metabolism disorder | 123.36 | 15.57 | 40 | 64366 | 332 | 34892193 |
Inflammation | 121.21 | 15.57 | 200 | 64206 | 28095 | 34864430 |
Dislocation of vertebra | 117.04 | 15.57 | 40 | 64366 | 397 | 34892128 |
Acne cystic | 114.45 | 15.57 | 41 | 64365 | 473 | 34892052 |
Dizziness | 114.21 | 15.57 | 141 | 64265 | 218380 | 34674145 |
Sarcoidosis | 113.16 | 15.57 | 69 | 64337 | 2819 | 34889706 |
Overdose | 112.03 | 15.57 | 17 | 64389 | 91042 | 34801483 |
Rhabdomyolysis | 107.91 | 15.57 | 4 | 64402 | 68159 | 34824366 |
Drug specific antibody present | 107.45 | 15.57 | 70 | 64336 | 3215 | 34889310 |
Vomiting | 104.81 | 15.57 | 185 | 64221 | 247436 | 34645089 |
Tooth loss | 104.18 | 15.57 | 73 | 64333 | 3785 | 34888740 |
Tongue disorder | 101.77 | 15.57 | 82 | 64324 | 5257 | 34887268 |
Intervertebral disc space narrowing | 101.50 | 15.57 | 46 | 64360 | 1009 | 34891516 |
Disease progression | 100.06 | 15.57 | 37 | 64369 | 108040 | 34784485 |
Joint arthroplasty | 99.07 | 15.57 | 43 | 64363 | 848 | 34891677 |
Pyrexia | 98.96 | 15.57 | 301 | 64105 | 332712 | 34559813 |
Rheumatoid factor positive | 98.51 | 15.57 | 40 | 64366 | 663 | 34891862 |
Decreased appetite | 98.29 | 15.57 | 97 | 64309 | 166295 | 34726230 |
Somnolence | 96.40 | 15.57 | 42 | 64364 | 111074 | 34781451 |
Neutropenia | 94.21 | 15.57 | 90 | 64316 | 156688 | 34735837 |
Osteolysis | 93.10 | 15.57 | 63 | 64343 | 3085 | 34889440 |
Bradycardia | 92.94 | 15.57 | 14 | 64392 | 75404 | 34817121 |
Hyperkalaemia | 92.47 | 15.57 | 10 | 64396 | 69379 | 34823146 |
Alopecia | 92.24 | 15.57 | 163 | 64243 | 24192 | 34868333 |
Foot deformity | 91.43 | 15.57 | 72 | 64334 | 4465 | 34888060 |
Hip arthroplasty | 90.09 | 15.57 | 71 | 64335 | 4408 | 34888117 |
Joint stiffness | 89.03 | 15.57 | 105 | 64301 | 10768 | 34881757 |
Seizure | 88.82 | 15.57 | 41 | 64365 | 104816 | 34787709 |
Infection | 87.89 | 15.57 | 366 | 64040 | 90549 | 34801976 |
Musculoskeletal discomfort | 86.98 | 15.57 | 90 | 64316 | 7978 | 34884547 |
Intestinal sepsis | 86.62 | 15.57 | 36 | 64370 | 635 | 34891890 |
Pulmonary fibrosis | 84.17 | 15.57 | 134 | 64272 | 18262 | 34874263 |
Epistaxis | 82.05 | 15.57 | 265 | 64141 | 57986 | 34834539 |
Gait inability | 79.99 | 15.57 | 140 | 64266 | 20618 | 34871907 |
Agitation | 79.82 | 15.57 | 7 | 64399 | 57392 | 34835133 |
Localised infection | 78.95 | 15.57 | 127 | 64279 | 17460 | 34875065 |
Ill-defined disorder | 78.87 | 15.57 | 112 | 64294 | 13797 | 34878728 |
Cardiac arrest | 77.79 | 15.57 | 40 | 64366 | 96119 | 34796406 |
Osteosclerosis | 77.15 | 15.57 | 41 | 64365 | 1283 | 34891242 |
Cytology abnormal | 74.52 | 15.57 | 28 | 64378 | 373 | 34892152 |
Tendonitis | 74.40 | 15.57 | 88 | 64318 | 9052 | 34883473 |
Fall | 74.21 | 15.57 | 165 | 64241 | 202720 | 34689805 |
Liver function test increased | 73.49 | 15.57 | 111 | 64295 | 14454 | 34878071 |
Drug use disorder | 72.82 | 15.57 | 61 | 64345 | 4130 | 34888395 |
Nodule | 71.60 | 15.57 | 75 | 64331 | 6744 | 34885781 |
Tooth fracture | 71.09 | 15.57 | 57 | 64349 | 3628 | 34888897 |
Skin ulcer | 70.72 | 15.57 | 138 | 64268 | 22078 | 34870447 |
Muscle spasms | 70.17 | 15.57 | 299 | 64107 | 74702 | 34817823 |
End stage renal disease | 69.96 | 15.57 | 84 | 64322 | 8777 | 34883748 |
Hepatic enzyme abnormal | 69.29 | 15.57 | 50 | 64356 | 2716 | 34889809 |
Joint range of motion decreased | 68.99 | 15.57 | 76 | 64330 | 7236 | 34885289 |
Hyponatraemia | 68.98 | 15.57 | 33 | 64373 | 82658 | 34809867 |
Soft tissue swelling | 68.98 | 15.57 | 29 | 64377 | 527 | 34891998 |
Photosensitivity reaction | 68.65 | 15.57 | 91 | 64315 | 10503 | 34882022 |
Intentional overdose | 67.65 | 15.57 | 3 | 64403 | 43671 | 34848854 |
Deep vein thrombosis | 67.24 | 15.57 | 268 | 64138 | 64980 | 34827545 |
Abdominal pain | 65.78 | 15.57 | 126 | 64280 | 163492 | 34729033 |
International normalised ratio increased | 65.19 | 15.57 | 6 | 64400 | 47321 | 34845204 |
Ankylosing spondylitis | 64.94 | 15.57 | 65 | 64341 | 5539 | 34886986 |
Hypokalaemia | 64.82 | 15.57 | 14 | 64392 | 58200 | 34834325 |
Seronegative arthritis | 62.88 | 15.57 | 33 | 64373 | 1006 | 34891519 |
Joint lock | 61.90 | 15.57 | 35 | 64371 | 1240 | 34891285 |
Tachycardia | 60.45 | 15.57 | 41 | 64365 | 84731 | 34807794 |
Ankle deformity | 60.43 | 15.57 | 21 | 64385 | 220 | 34892305 |
Syncope | 60.33 | 15.57 | 48 | 64358 | 91403 | 34801122 |
Haemorrhage | 60.03 | 15.57 | 11 | 64395 | 51359 | 34841166 |
Platelet count decreased | 59.59 | 15.57 | 80 | 64326 | 119637 | 34772888 |
Suicide attempt | 59.57 | 15.57 | 3 | 64403 | 39113 | 34853412 |
Grip strength decreased | 58.97 | 15.57 | 48 | 64358 | 3121 | 34889404 |
Plasma cell myeloma | 58.79 | 15.57 | 5 | 64401 | 42032 | 34850493 |
Atrial fibrillation | 58.71 | 15.57 | 84 | 64322 | 122309 | 34770216 |
Cardiac failure congestive | 58.41 | 15.57 | 41 | 64365 | 83229 | 34809296 |
Psoriasis | 57.77 | 15.57 | 180 | 64226 | 38632 | 34853893 |
Mental status changes | 57.74 | 15.57 | 3 | 64403 | 38080 | 34854445 |
Dyspnoea | 56.40 | 15.57 | 435 | 63971 | 376347 | 34516178 |
Hallucination | 56.09 | 15.57 | 13 | 64393 | 51485 | 34841040 |
Skin laceration | 54.33 | 15.57 | 89 | 64317 | 12420 | 34880105 |
Arthritis bacterial | 53.32 | 15.57 | 56 | 64350 | 5050 | 34887475 |
Joint effusion | 52.53 | 15.57 | 56 | 64350 | 5137 | 34887388 |
Blood glucose increased | 52.11 | 15.57 | 29 | 64377 | 66689 | 34825836 |
Hypoglycaemia | 51.74 | 15.57 | 18 | 64388 | 54622 | 34837903 |
Neutrophil count decreased | 51.65 | 15.57 | 15 | 64391 | 51089 | 34841436 |
Pneumonia aspiration | 51.11 | 15.57 | 8 | 64398 | 41895 | 34850630 |
Abdominal discomfort | 50.24 | 15.57 | 231 | 64175 | 59604 | 34832921 |
Mass | 49.84 | 15.57 | 67 | 64339 | 7838 | 34884687 |
Hepatic cirrhosis | 49.67 | 15.57 | 103 | 64303 | 17211 | 34875314 |
Myalgia | 49.64 | 15.57 | 49 | 64357 | 84061 | 34808464 |
Electrocardiogram QT prolonged | 49.54 | 15.57 | 8 | 64398 | 40944 | 34851581 |
Musculoskeletal disorder | 49.28 | 15.57 | 59 | 64347 | 6145 | 34886380 |
Product dose omission issue | 49.13 | 15.57 | 91 | 64315 | 119620 | 34772905 |
Polyomavirus-associated nephropathy | 49.04 | 15.57 | 47 | 64359 | 3797 | 34888728 |
Ureaplasma infection | 48.21 | 15.57 | 20 | 64386 | 351 | 34892174 |
Liver disorder | 48.15 | 15.57 | 152 | 64254 | 32845 | 34859680 |
Exposure via body fluid | 48.12 | 15.57 | 15 | 64391 | 108 | 34892417 |
Cardio-respiratory arrest | 47.73 | 15.57 | 21 | 64385 | 55252 | 34837273 |
Musculoskeletal pain | 47.34 | 15.57 | 148 | 64258 | 31815 | 34860710 |
Urinary tract infection | 47.34 | 15.57 | 51 | 64355 | 84030 | 34808495 |
Hyperglycaemia | 47.11 | 15.57 | 8 | 64398 | 39472 | 34853053 |
Prerenal failure | 46.20 | 15.57 | 35 | 64371 | 2049 | 34890476 |
Delirium | 46.17 | 15.57 | 12 | 64394 | 43979 | 34848546 |
Fine motor skill dysfunction | 46.11 | 15.57 | 33 | 64373 | 1769 | 34890756 |
Hospitalisation | 45.50 | 15.57 | 24 | 64382 | 56878 | 34835647 |
Diabetes mellitus | 45.47 | 15.57 | 189 | 64217 | 46684 | 34845841 |
Oral surgery | 45.29 | 15.57 | 22 | 64384 | 567 | 34891958 |
Loss of consciousness | 44.50 | 15.57 | 52 | 64354 | 82615 | 34809910 |
Finger deformity | 44.07 | 15.57 | 30 | 64376 | 1483 | 34891042 |
Blood creatine phosphokinase increased | 43.83 | 15.57 | 14 | 64392 | 44843 | 34847682 |
Physical disability | 43.78 | 15.57 | 29 | 64377 | 1370 | 34891155 |
Pulmonary mass | 43.74 | 15.57 | 82 | 64324 | 12730 | 34879795 |
Therapeutic response decreased | 43.66 | 15.57 | 136 | 64270 | 29177 | 34863348 |
Tuberculin test positive | 43.47 | 15.57 | 27 | 64379 | 1140 | 34891385 |
Rheumatoid lung | 43.43 | 15.57 | 25 | 64381 | 917 | 34891608 |
Intentional product misuse | 43.23 | 15.57 | 15 | 64391 | 45596 | 34846929 |
Interstitial lung disease | 42.78 | 15.57 | 235 | 64171 | 65047 | 34827478 |
Granuloma | 41.95 | 15.57 | 40 | 64366 | 3211 | 34889314 |
Cerebrovascular accident | 40.85 | 15.57 | 58 | 64348 | 84753 | 34807772 |
Food intolerance | 40.75 | 15.57 | 28 | 64378 | 1406 | 34891119 |
Red blood cell sedimentation rate | 40.54 | 15.57 | 26 | 64380 | 1162 | 34891363 |
Abdominal distension | 39.45 | 15.57 | 30 | 64376 | 58462 | 34834063 |
Respiratory failure | 39.06 | 15.57 | 89 | 64317 | 108483 | 34784042 |
Tooth disorder | 38.85 | 15.57 | 71 | 64335 | 10811 | 34881714 |
Granuloma skin | 38.79 | 15.57 | 26 | 64380 | 1253 | 34891272 |
Dactylitis | 38.63 | 15.57 | 23 | 64383 | 899 | 34891626 |
Medical device implantation | 38.22 | 15.57 | 20 | 64386 | 606 | 34891919 |
Urinary retention | 37.88 | 15.57 | 10 | 64396 | 36278 | 34856247 |
Dysarthria | 37.44 | 15.57 | 9 | 64397 | 34773 | 34857752 |
Haematuria | 37.34 | 15.57 | 23 | 64383 | 50043 | 34842482 |
X-ray abnormal | 37.09 | 15.57 | 18 | 64388 | 463 | 34892062 |
Skin mass | 36.87 | 15.57 | 41 | 64365 | 3944 | 34888581 |
Immobile | 36.66 | 15.57 | 33 | 64373 | 2461 | 34890064 |
Limb deformity | 36.39 | 15.57 | 19 | 64387 | 573 | 34891952 |
Flushing | 35.67 | 15.57 | 8 | 64398 | 32412 | 34860113 |
Metabolic acidosis | 35.55 | 15.57 | 18 | 64388 | 43662 | 34848863 |
Lactic acidosis | 35.52 | 15.57 | 10 | 64396 | 34762 | 34857763 |
Coma | 35.45 | 15.57 | 20 | 64386 | 45658 | 34846867 |
Stent placement | 35.05 | 15.57 | 45 | 64361 | 5033 | 34887492 |
Gastrointestinal haemorrhage | 34.76 | 15.57 | 69 | 64337 | 88408 | 34804117 |
Unresponsive to stimuli | 34.22 | 15.57 | 5 | 64401 | 27564 | 34864961 |
Product use in unapproved indication | 33.47 | 15.57 | 108 | 64298 | 117391 | 34775134 |
Blood parathyroid hormone decreased | 33.12 | 15.57 | 25 | 64381 | 1455 | 34891070 |
Neoplasm malignant | 33.08 | 15.57 | 96 | 64310 | 19809 | 34872716 |
Pulmonary embolism | 32.93 | 15.57 | 280 | 64126 | 89466 | 34803059 |
Exostosis | 32.82 | 15.57 | 42 | 64364 | 4681 | 34887844 |
Hypoxia | 32.61 | 15.57 | 32 | 64374 | 55063 | 34837462 |
Coronary artery disease | 32.29 | 15.57 | 25 | 64381 | 48280 | 34844245 |
Pyopneumothorax | 32.08 | 15.57 | 10 | 64396 | 72 | 34892453 |
Asthenia | 31.70 | 15.57 | 294 | 64112 | 244957 | 34647568 |
Respiratory distress | 31.67 | 15.57 | 13 | 64393 | 35652 | 34856873 |
Blood creatinine increased | 31.67 | 15.57 | 81 | 64325 | 94895 | 34797630 |
Blood pressure decreased | 31.56 | 15.57 | 29 | 64377 | 51486 | 34841039 |
Depressed level of consciousness | 31.50 | 15.57 | 20 | 64386 | 42821 | 34849704 |
Intestinal obstruction | 31.14 | 15.57 | 3 | 64403 | 22819 | 34869706 |
Hypocalcaemia | 31.11 | 15.57 | 4 | 64402 | 24285 | 34868240 |
Mycobacterium tuberculosis complex test positive | 30.93 | 15.57 | 23 | 64383 | 1309 | 34891216 |
Suicidal ideation | 30.89 | 15.57 | 18 | 64388 | 40370 | 34852155 |
Pancreatitis acute | 30.85 | 15.57 | 7 | 64399 | 28134 | 34864391 |
Dermatitis psoriasiform | 30.70 | 15.57 | 24 | 64382 | 1472 | 34891053 |
Dysphagia | 30.69 | 15.57 | 42 | 64364 | 62339 | 34830186 |
Panniculitis | 30.53 | 15.57 | 27 | 64379 | 1967 | 34890558 |
Chest pain | 30.51 | 15.57 | 125 | 64281 | 126637 | 34765888 |
Hepatotoxicity | 30.45 | 15.57 | 98 | 64308 | 21387 | 34871138 |
Septic shock | 29.99 | 15.57 | 54 | 64352 | 71780 | 34820745 |
Hepatic enzyme increased | 29.97 | 15.57 | 147 | 64259 | 38933 | 34853592 |
Hypomagnesaemia | 29.48 | 15.57 | 3 | 64403 | 21848 | 34870677 |
Polyarthritis | 29.41 | 15.57 | 39 | 64367 | 4501 | 34888024 |
Toxic epidermal necrolysis | 29.13 | 15.57 | 3 | 64403 | 21643 | 34870882 |
Hepatic fibrosis | 28.97 | 15.57 | 39 | 64367 | 4568 | 34887957 |
Renal impairment | 28.96 | 15.57 | 84 | 64322 | 94429 | 34798096 |
Fibromyalgia | 28.86 | 15.57 | 32 | 64374 | 3068 | 34889457 |
Respiratory arrest | 28.76 | 15.57 | 8 | 64398 | 28035 | 34864490 |
Skin injury | 28.65 | 15.57 | 28 | 64378 | 2317 | 34890208 |
Degenerative bone disease | 28.61 | 15.57 | 9 | 64397 | 67 | 34892458 |
Histoplasmosis | 28.26 | 15.57 | 23 | 64383 | 1495 | 34891030 |
Dysgeusia | 28.24 | 15.57 | 7 | 64399 | 26490 | 34866035 |
Hepatic steatosis | 28.09 | 15.57 | 86 | 64320 | 18276 | 34874249 |
Disorientation | 28.04 | 15.57 | 13 | 64393 | 33175 | 34859350 |
Chills | 27.88 | 15.57 | 68 | 64338 | 80975 | 34811550 |
Oedema | 27.73 | 15.57 | 26 | 64380 | 45715 | 34846810 |
Wrong technique in product usage process | 27.58 | 15.57 | 16 | 64390 | 35970 | 34856555 |
Condition aggravated | 27.48 | 15.57 | 502 | 63904 | 191694 | 34700831 |
Lacrimal disorder | 27.20 | 15.57 | 13 | 64393 | 323 | 34892202 |
Subdural haematoma | 27.05 | 15.57 | 3 | 64403 | 20418 | 34872107 |
Neck pain | 26.79 | 15.57 | 105 | 64301 | 25244 | 34867281 |
Oral disorder | 26.76 | 15.57 | 36 | 64370 | 4213 | 34888312 |
Bursitis | 26.69 | 15.57 | 41 | 64365 | 5417 | 34887108 |
Restlessness | 26.64 | 15.57 | 7 | 64399 | 25475 | 34867050 |
Alanine aminotransferase increased | 26.48 | 15.57 | 246 | 64160 | 80569 | 34811956 |
Foetal exposure during pregnancy | 26.39 | 15.57 | 19 | 64387 | 38082 | 34854443 |
Latent tuberculosis | 26.11 | 15.57 | 21 | 64385 | 1342 | 34891183 |
Wrist deformity | 26.04 | 15.57 | 13 | 64393 | 356 | 34892169 |
Generalised tonic-clonic seizure | 25.91 | 15.57 | 4 | 64402 | 21170 | 34871355 |
Pulmonary toxicity | 25.70 | 15.57 | 43 | 64363 | 6104 | 34886421 |
Irritability | 25.40 | 15.57 | 7 | 64399 | 24683 | 34867842 |
Lymphoedema | 25.34 | 15.57 | 34 | 64372 | 3969 | 34888556 |
Speech disorder | 25.12 | 15.57 | 8 | 64398 | 25678 | 34866847 |
Blood cholesterol abnormal | 24.80 | 15.57 | 23 | 64383 | 1783 | 34890742 |
Therapy non-responder | 24.36 | 15.57 | 139 | 64267 | 39007 | 34853518 |
Intentional product use issue | 24.29 | 15.57 | 191 | 64215 | 59625 | 34832900 |
Heart block congenital | 24.29 | 15.57 | 7 | 64399 | 37 | 34892488 |
White blood cell count increased | 24.23 | 15.57 | 24 | 64382 | 41127 | 34851398 |
Multiple organ dysfunction syndrome | 24.23 | 15.57 | 67 | 64339 | 76499 | 34816026 |
Accidental overdose | 24.21 | 15.57 | 4 | 64402 | 20136 | 34872389 |
Hypertension | 24.12 | 15.57 | 369 | 64037 | 136074 | 34756451 |
Renal failure | 23.82 | 15.57 | 355 | 64051 | 130202 | 34762323 |
Orthostatic hypotension | 23.75 | 15.57 | 9 | 64397 | 25910 | 34866615 |
Enzyme abnormality | 23.67 | 15.57 | 11 | 64395 | 256 | 34892269 |
Gastric disorder | 23.63 | 15.57 | 63 | 64343 | 12378 | 34880147 |
Cerebral haemorrhage | 23.45 | 15.57 | 18 | 64388 | 34919 | 34857606 |
Splenic embolism | 23.43 | 15.57 | 10 | 64396 | 189 | 34892336 |
Diarrhoea | 23.36 | 15.57 | 544 | 63862 | 389368 | 34503157 |
Elbow operation | 23.29 | 15.57 | 9 | 64397 | 130 | 34892395 |
Vasculitic rash | 23.26 | 15.57 | 17 | 64389 | 942 | 34891583 |
Synovial cyst | 23.22 | 15.57 | 25 | 64381 | 2319 | 34890206 |
Full blood count decreased | 23.11 | 15.57 | 3 | 64403 | 18085 | 34874440 |
Shoulder operation | 22.97 | 15.57 | 18 | 64388 | 1108 | 34891417 |
Fatigue | 22.80 | 15.57 | 515 | 63891 | 370138 | 34522387 |
Cutaneous symptom | 22.59 | 15.57 | 11 | 64395 | 285 | 34892240 |
Dysstasia | 22.40 | 15.57 | 61 | 64345 | 12134 | 34880391 |
Blood pressure fluctuation | 22.31 | 15.57 | 99 | 64307 | 25150 | 34867375 |
Epilepsy | 22.29 | 15.57 | 6 | 64400 | 21489 | 34871036 |
Tendon disorder | 22.28 | 15.57 | 27 | 64379 | 2848 | 34889677 |
Acute respiratory failure | 21.98 | 15.57 | 15 | 64391 | 30913 | 34861612 |
Retinal scar | 21.84 | 15.57 | 11 | 64395 | 307 | 34892218 |
Onycholysis | 21.76 | 15.57 | 15 | 64391 | 757 | 34891768 |
Haematoma | 21.67 | 15.57 | 10 | 64396 | 25595 | 34866930 |
Melaena | 21.57 | 15.57 | 20 | 64386 | 35360 | 34857165 |
Ventricular tachycardia | 21.56 | 15.57 | 11 | 64395 | 26568 | 34865957 |
Pulmonary cavitation | 21.46 | 15.57 | 16 | 64390 | 914 | 34891611 |
Erythema | 21.42 | 15.57 | 254 | 64152 | 88526 | 34803999 |
Hypervolaemia | 21.41 | 15.57 | 5 | 64401 | 19704 | 34872821 |
Rash maculo-papular | 21.31 | 15.57 | 13 | 64393 | 28438 | 34864087 |
Bone marrow oedema | 21.20 | 15.57 | 14 | 64392 | 658 | 34891867 |
Cytomegalovirus syndrome | 21.13 | 15.57 | 8 | 64398 | 109 | 34892416 |
Aortic bruit | 21.13 | 15.57 | 10 | 64396 | 243 | 34892282 |
Cytomegalovirus viraemia | 21.07 | 15.57 | 44 | 64362 | 7386 | 34885139 |
Injury | 21.03 | 15.57 | 6 | 64400 | 20681 | 34871844 |
Tooth extraction | 21.02 | 15.57 | 34 | 64372 | 4694 | 34887831 |
C-reactive protein decreased | 20.98 | 15.57 | 22 | 64384 | 1980 | 34890545 |
Head injury | 20.97 | 15.57 | 4 | 64402 | 18156 | 34874369 |
Drug reaction with eosinophilia and systemic symptoms | 20.92 | 15.57 | 18 | 64388 | 32994 | 34859531 |
Sideroblastic anaemia | 20.90 | 15.57 | 10 | 64396 | 249 | 34892276 |
COVID-19 | 20.90 | 15.57 | 73 | 64333 | 77477 | 34815048 |
Ossicle disorder | 20.78 | 15.57 | 6 | 64400 | 32 | 34892493 |
Disturbance in attention | 20.65 | 15.57 | 11 | 64395 | 25934 | 34866591 |
Arthrodesis | 20.60 | 15.57 | 12 | 64394 | 450 | 34892075 |
Lymphocyte count decreased | 20.48 | 15.57 | 8 | 64398 | 22614 | 34869911 |
Memory impairment | 20.48 | 15.57 | 30 | 64376 | 43288 | 34849237 |
Surgery | 20.45 | 15.57 | 65 | 64341 | 14092 | 34878433 |
Ascites | 20.35 | 15.57 | 34 | 64372 | 46537 | 34845988 |
Medication error | 20.11 | 15.57 | 11 | 64395 | 25554 | 34866971 |
Spina bifida occulta | 20.11 | 15.57 | 5 | 64401 | 13 | 34892512 |
Dysphonia | 20.00 | 15.57 | 9 | 64397 | 23374 | 34869151 |
Impaired healing | 19.99 | 15.57 | 68 | 64338 | 15266 | 34877259 |
Diaphragmatic injury | 19.96 | 15.57 | 8 | 64398 | 128 | 34892397 |
Lupus-like syndrome | 19.93 | 15.57 | 25 | 64381 | 2731 | 34889794 |
Steatorrhoea | 19.92 | 15.57 | 14 | 64392 | 729 | 34891796 |
Lethargy | 19.91 | 15.57 | 28 | 64378 | 41094 | 34851431 |
Emphysema | 19.91 | 15.57 | 50 | 64356 | 9475 | 34883050 |
Shoulder arthroplasty | 19.88 | 15.57 | 12 | 64394 | 481 | 34892044 |
Thrombosis | 19.87 | 15.57 | 160 | 64246 | 50298 | 34842227 |
Fear of injection | 19.84 | 15.57 | 19 | 64387 | 1533 | 34890992 |
Full blood count abnormal | 19.76 | 15.57 | 5 | 64401 | 18663 | 34873862 |
Vision blurred | 19.68 | 15.57 | 34 | 64372 | 45929 | 34846596 |
Cell-mediated cytotoxicity | 19.64 | 15.57 | 6 | 64400 | 40 | 34892485 |
Anaphylactic shock | 19.53 | 15.57 | 3 | 64403 | 15938 | 34876587 |
Altered state of consciousness | 19.29 | 15.57 | 9 | 64397 | 22884 | 34869641 |
Unevaluable event | 19.20 | 15.57 | 19 | 64387 | 32571 | 34859954 |
Fluid retention | 19.16 | 15.57 | 13 | 64393 | 26874 | 34865651 |
Nail pitting | 19.05 | 15.57 | 10 | 64396 | 305 | 34892220 |
Chronic kidney disease | 19.03 | 15.57 | 29 | 64377 | 41181 | 34851344 |
Diffuse idiopathic skeletal hyperostosis | 18.92 | 15.57 | 6 | 64400 | 46 | 34892479 |
Immobilisation syndrome | 18.90 | 15.57 | 10 | 64396 | 310 | 34892215 |
Vitello-intestinal duct remnant | 18.80 | 15.57 | 8 | 64398 | 150 | 34892375 |
Ejection fraction decreased | 18.67 | 15.57 | 6 | 64400 | 19148 | 34873377 |
Cartilage injury | 18.52 | 15.57 | 12 | 64394 | 546 | 34891979 |
Cardiac granuloma | 18.43 | 15.57 | 4 | 64402 | 4 | 34892521 |
Upper respiratory tract infection | 18.39 | 15.57 | 114 | 64292 | 32945 | 34859580 |
Vitamin B1 decreased | 18.39 | 15.57 | 10 | 64396 | 328 | 34892197 |
Paternal drugs affecting foetus | 18.38 | 15.57 | 6 | 64400 | 51 | 34892474 |
Ileus | 18.29 | 15.57 | 4 | 64402 | 16495 | 34876030 |
Oral pustule | 18.18 | 15.57 | 9 | 64397 | 242 | 34892283 |
Product administration error | 18.04 | 15.57 | 4 | 64402 | 16340 | 34876185 |
Dental caries | 17.98 | 15.57 | 31 | 64375 | 4508 | 34888017 |
Drug withdrawal syndrome | 17.98 | 15.57 | 7 | 64399 | 19827 | 34872698 |
Joint injury | 17.98 | 15.57 | 47 | 64359 | 9126 | 34883399 |
Hypophagia | 17.95 | 15.57 | 11 | 64395 | 24011 | 34868514 |
Gastritis | 17.82 | 15.57 | 9 | 64397 | 21864 | 34870661 |
Haemoptysis | 17.79 | 15.57 | 23 | 64383 | 34983 | 34857542 |
Swollen joint count increased | 17.75 | 15.57 | 9 | 64397 | 255 | 34892270 |
Arrhythmia | 17.72 | 15.57 | 24 | 64382 | 35784 | 34856741 |
Dyspnoea exertional | 17.64 | 15.57 | 33 | 64373 | 43246 | 34849279 |
Blood bilirubin increased | 17.64 | 15.57 | 27 | 64379 | 38269 | 34854256 |
Fracture | 17.63 | 15.57 | 39 | 64367 | 6810 | 34885715 |
Granulomatous dermatitis | 17.59 | 15.57 | 9 | 64397 | 260 | 34892265 |
Erythema elevatum diutinum | 17.58 | 15.57 | 5 | 64401 | 25 | 34892500 |
Transient ischaemic attack | 17.57 | 15.57 | 15 | 64391 | 27598 | 34864927 |
Erectile dysfunction | 17.56 | 15.57 | 8 | 64398 | 20629 | 34871896 |
Carbon dioxide abnormal | 17.38 | 15.57 | 8 | 64398 | 182 | 34892343 |
Cerebral infarction | 17.36 | 15.57 | 15 | 64391 | 27440 | 34865085 |
Sensitivity to weather change | 17.27 | 15.57 | 18 | 64388 | 1608 | 34890917 |
Otospondylomegaepiphyseal dysplasia | 17.19 | 15.57 | 7 | 64399 | 117 | 34892408 |
Anal hypoaesthesia | 17.16 | 15.57 | 4 | 64402 | 7 | 34892518 |
Renal tubular necrosis | 16.99 | 15.57 | 4 | 64402 | 15676 | 34876849 |
Diabetic ketoacidosis | 16.96 | 15.57 | 6 | 64400 | 18026 | 34874499 |
Tuberculosis | 16.87 | 15.57 | 44 | 64362 | 8533 | 34883992 |
Hernia pain | 16.86 | 15.57 | 9 | 64397 | 284 | 34892241 |
Shock | 16.82 | 15.57 | 12 | 64394 | 24167 | 34868358 |
Empyema | 16.80 | 15.57 | 25 | 64381 | 3211 | 34889314 |
Soft tissue inflammation | 16.66 | 15.57 | 7 | 64399 | 127 | 34892398 |
Carditis | 16.62 | 15.57 | 8 | 64398 | 202 | 34892323 |
Stress ulcer | 16.61 | 15.57 | 6 | 64400 | 71 | 34892454 |
Exposure via father | 16.56 | 15.57 | 7 | 64399 | 129 | 34892396 |
Urinary incontinence | 16.56 | 15.57 | 7 | 64399 | 18867 | 34873658 |
Ventricular fibrillation | 16.49 | 15.57 | 11 | 64395 | 22943 | 34869582 |
C-reactive protein | 16.41 | 15.57 | 7 | 64399 | 132 | 34892393 |
Undifferentiated connective tissue disease | 16.41 | 15.57 | 5 | 64401 | 33 | 34892492 |
Blood potassium increased | 16.37 | 15.57 | 5 | 64401 | 16490 | 34876035 |
Pulmonary granuloma | 16.37 | 15.57 | 17 | 64389 | 1513 | 34891012 |
Motor dysfunction | 16.06 | 15.57 | 38 | 64368 | 6936 | 34885589 |
Ulcer | 16.04 | 15.57 | 44 | 64362 | 8791 | 34883734 |
Pallor | 16.02 | 15.57 | 14 | 64392 | 25466 | 34867059 |
Aphthous ulcer | 15.86 | 15.57 | 31 | 64375 | 4964 | 34887561 |
Aphasia | 15.79 | 15.57 | 10 | 64396 | 21444 | 34871081 |
Dyskinesia | 15.75 | 15.57 | 11 | 64395 | 22402 | 34870123 |
Urticarial vasculitis | 15.69 | 15.57 | 5 | 64401 | 39 | 34892486 |
Neutrophil count increased | 15.63 | 15.57 | 6 | 64400 | 17140 | 34875385 |
MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
---|---|---|---|---|---|---|
Drug ineffective | 6120.21 | 13.77 | 14348 | 346154 | 1066565 | 78317321 |
Drug intolerance | 5601.12 | 13.77 | 6414 | 354088 | 257705 | 79126181 |
Joint swelling | 4634.96 | 13.77 | 6094 | 354408 | 282552 | 79101334 |
Contraindicated product administered | 3941.08 | 13.77 | 4177 | 356325 | 153361 | 79230525 |
Synovitis | 3863.70 | 13.77 | 4049 | 356453 | 146685 | 79237201 |
Rheumatoid arthritis | 3780.42 | 13.77 | 4679 | 355823 | 203791 | 79180095 |
Treatment failure | 3211.12 | 13.77 | 3902 | 356600 | 166584 | 79217302 |
Arthropathy | 2907.53 | 13.77 | 3785 | 356717 | 173326 | 79210560 |
Therapeutic product effect decreased | 2548.51 | 13.77 | 3411 | 357091 | 160452 | 79223434 |
Hand deformity | 1845.28 | 13.77 | 2311 | 358191 | 101608 | 79282278 |
Arthralgia | 1823.74 | 13.77 | 6196 | 354306 | 565607 | 78818279 |
Swelling | 1781.06 | 13.77 | 3370 | 357132 | 213341 | 79170545 |
Pain | 1672.37 | 13.77 | 6938 | 353564 | 696864 | 78687022 |
Pemphigus | 1584.96 | 13.77 | 2098 | 358404 | 97484 | 79286402 |
Death | 1511.34 | 13.77 | 355 | 360147 | 566159 | 78817727 |
Abdominal discomfort | 1498.78 | 13.77 | 3421 | 357081 | 247306 | 79136580 |
Anti-cyclic citrullinated peptide antibody positive | 1482.04 | 13.77 | 1853 | 358649 | 81290 | 79302596 |
Systemic lupus erythematosus | 1476.70 | 13.77 | 2247 | 358255 | 118902 | 79264984 |
C-reactive protein abnormal | 1444.27 | 13.77 | 1413 | 359089 | 46954 | 79336932 |
Musculoskeletal stiffness | 1433.99 | 13.77 | 2719 | 357783 | 172289 | 79211597 |
Alopecia | 1425.24 | 13.77 | 3195 | 357307 | 228160 | 79155726 |
Acute kidney injury | 1368.36 | 13.77 | 334 | 360168 | 519070 | 78864816 |
Glossodynia | 1355.63 | 13.77 | 1984 | 358518 | 101353 | 79282533 |
Drug hypersensitivity | 1354.56 | 13.77 | 3669 | 356833 | 295247 | 79088639 |
Rheumatoid factor positive | 1350.54 | 13.77 | 1505 | 358997 | 58334 | 79325552 |
Hepatic enzyme increased | 1339.41 | 13.77 | 2708 | 357794 | 179902 | 79203984 |
Hypersensitivity | 1291.81 | 13.77 | 3321 | 357181 | 258918 | 79124968 |
Peripheral swelling | 1269.31 | 13.77 | 3357 | 357145 | 266260 | 79117626 |
Hypotension | 1096.88 | 13.77 | 316 | 360186 | 440001 | 78943885 |
Pericarditis | 1076.67 | 13.77 | 1793 | 358709 | 102443 | 79281443 |
Toxicity to various agents | 1034.43 | 13.77 | 311 | 360191 | 421229 | 78962657 |
Red blood cell sedimentation rate abnormal | 1016.98 | 13.77 | 807 | 359695 | 20156 | 79363730 |
Completed suicide | 1016.40 | 13.77 | 19 | 360483 | 245748 | 79138138 |
Psoriatic arthropathy | 994.46 | 13.77 | 1478 | 359024 | 76521 | 79307365 |
Wound | 968.17 | 13.77 | 1819 | 358683 | 114360 | 79269526 |
Therapeutic product effect incomplete | 966.83 | 13.77 | 2040 | 358462 | 139605 | 79244281 |
Drug interaction | 910.88 | 13.77 | 369 | 360133 | 414814 | 78969072 |
Febrile neutropenia | 898.70 | 13.77 | 33 | 360469 | 230966 | 79152920 |
Red blood cell sedimentation rate increased | 855.33 | 13.77 | 1047 | 359455 | 44895 | 79338991 |
Anaemia | 852.99 | 13.77 | 476 | 360026 | 444539 | 78939347 |
Loss of personal independence in daily activities | 840.84 | 13.77 | 1595 | 358907 | 100985 | 79282901 |
Helicobacter infection | 839.01 | 13.77 | 1286 | 359216 | 68418 | 79315468 |
Duodenal ulcer perforation | 787.68 | 13.77 | 1215 | 359287 | 64996 | 79318890 |
Discomfort | 773.64 | 13.77 | 1736 | 358766 | 123881 | 79260005 |
Rash | 762.03 | 13.77 | 4840 | 355662 | 573518 | 78810368 |
Constipation | 742.36 | 13.77 | 183 | 360319 | 282867 | 79101019 |
Infection | 739.26 | 13.77 | 2588 | 357914 | 239124 | 79144762 |
Bone erosion | 729.48 | 13.77 | 622 | 359880 | 17225 | 79366661 |
Infusion related reaction | 715.20 | 13.77 | 2478 | 358024 | 227759 | 79156127 |
Gastrointestinal disorder | 711.69 | 13.77 | 1652 | 358850 | 120553 | 79263333 |
C-reactive protein increased | 702.43 | 13.77 | 1699 | 358803 | 127328 | 79256558 |
Impaired healing | 702.33 | 13.77 | 1350 | 359152 | 86305 | 79297581 |
Mobility decreased | 679.27 | 13.77 | 1622 | 358880 | 120553 | 79263333 |
Sleep disorder due to general medical condition, insomnia type | 675.98 | 13.77 | 907 | 359595 | 42649 | 79341237 |
Irritable bowel syndrome | 668.41 | 13.77 | 1090 | 359412 | 61151 | 79322735 |
Folliculitis | 663.94 | 13.77 | 1020 | 359482 | 54360 | 79329526 |
Muscle injury | 661.99 | 13.77 | 950 | 359552 | 47611 | 79336275 |
Dehydration | 613.84 | 13.77 | 180 | 360322 | 248007 | 79135879 |
Osteoarthritis | 605.27 | 13.77 | 1266 | 359236 | 86043 | 79297843 |
Malignant neoplasm progression | 591.15 | 13.77 | 4 | 360498 | 135986 | 79247900 |
Lower respiratory tract infection | 576.64 | 13.77 | 1579 | 358923 | 127641 | 79256245 |
Hyponatraemia | 554.21 | 13.77 | 74 | 360428 | 177774 | 79206112 |
Arthritis | 545.00 | 13.77 | 1436 | 359066 | 113444 | 79270442 |
Cardiac arrest | 544.97 | 13.77 | 68 | 360434 | 172028 | 79211858 |
Thrombocytopenia | 533.81 | 13.77 | 266 | 360236 | 264993 | 79118893 |
Ill-defined disorder | 531.81 | 13.77 | 1018 | 359484 | 64857 | 79319029 |
Rheumatoid nodule | 519.44 | 13.77 | 509 | 359993 | 16929 | 79366957 |
Bradycardia | 511.54 | 13.77 | 24 | 360478 | 135533 | 79248353 |
Overdose | 508.98 | 13.77 | 106 | 360396 | 184100 | 79199786 |
Seizure | 502.91 | 13.77 | 118 | 360384 | 188716 | 79195170 |
Somnolence | 492.48 | 13.77 | 232 | 360270 | 238749 | 79145137 |
Inflammation | 491.41 | 13.77 | 1217 | 359285 | 92536 | 79291350 |
Blister | 488 | 13.77 | 1414 | 359088 | 118062 | 79265824 |
Disease progression | 483.53 | 13.77 | 119 | 360383 | 184243 | 79199643 |
Stomatitis | 476.70 | 13.77 | 1604 | 358898 | 145153 | 79238733 |
Neutropenia | 475.61 | 13.77 | 363 | 360139 | 287347 | 79096539 |
Condition aggravated | 464.91 | 13.77 | 3858 | 356644 | 497266 | 78886620 |
Sinusitis | 446.39 | 13.77 | 1909 | 358593 | 193592 | 79190294 |
Knee arthroplasty | 443.55 | 13.77 | 742 | 359760 | 42506 | 79341380 |
Fibromyalgia | 440.07 | 13.77 | 928 | 359574 | 63412 | 79320474 |
Intentional overdose | 434.55 | 13.77 | 9 | 360493 | 105951 | 79277935 |
Product use issue | 433.08 | 13.77 | 1988 | 358514 | 207834 | 79176052 |
Hyperkalaemia | 426.04 | 13.77 | 22 | 360480 | 114376 | 79269510 |
Maternal exposure during pregnancy | 424.72 | 13.77 | 1471 | 359031 | 135067 | 79248819 |
Tremor | 417.39 | 13.77 | 125 | 360377 | 169958 | 79213928 |
Foot deformity | 397.67 | 13.77 | 517 | 359985 | 23557 | 79360329 |
Disability | 397.03 | 13.77 | 437 | 360065 | 16683 | 79367203 |
Fall | 386.54 | 13.77 | 1038 | 359464 | 486591 | 78897295 |
Atrial fibrillation | 383.81 | 13.77 | 208 | 360294 | 197678 | 79186208 |
Dyspnoea | 372.69 | 13.77 | 2311 | 358191 | 854714 | 78529172 |
Hip arthroplasty | 368.71 | 13.77 | 615 | 359887 | 35141 | 79348745 |
Joint range of motion decreased | 353.33 | 13.77 | 580 | 359922 | 32702 | 79351184 |
Tenosynovitis | 352.02 | 13.77 | 392 | 360110 | 15162 | 79368724 |
Blood cholesterol increased | 348.67 | 13.77 | 998 | 359504 | 82722 | 79301164 |
Drug tolerance decreased | 344.66 | 13.77 | 356 | 360146 | 12622 | 79371264 |
Hypokalaemia | 340.66 | 13.77 | 113 | 360389 | 143927 | 79239959 |
Electrocardiogram QT prolonged | 337.77 | 13.77 | 17 | 360485 | 90369 | 79293517 |
Tachycardia | 330.18 | 13.77 | 197 | 360305 | 177571 | 79206315 |
Rhabdomyolysis | 328.25 | 13.77 | 40 | 360462 | 103091 | 79280795 |
Respiratory failure | 324.22 | 13.77 | 209 | 360293 | 180702 | 79203184 |
Depressed level of consciousness | 318.92 | 13.77 | 33 | 360469 | 96619 | 79287267 |
Osteoporosis | 317.46 | 13.77 | 734 | 359768 | 53378 | 79330508 |
Dizziness | 317.17 | 13.77 | 1265 | 359237 | 525176 | 78858710 |
Platelet count decreased | 314.69 | 13.77 | 251 | 360251 | 194413 | 79189473 |
Cardio-respiratory arrest | 313.28 | 13.77 | 56 | 360446 | 108454 | 79275432 |
Musculoskeletal disorder | 312.07 | 13.77 | 433 | 360069 | 21015 | 79362871 |
Sepsis | 308.94 | 13.77 | 462 | 360040 | 268966 | 79114920 |
Hypoglycaemia | 303.11 | 13.77 | 48 | 360454 | 101546 | 79282340 |
Adverse event | 302.17 | 13.77 | 769 | 359733 | 59445 | 79324441 |
Rheumatic fever | 299.97 | 13.77 | 495 | 360007 | 28030 | 79355856 |
Suicide attempt | 290.70 | 13.77 | 22 | 360480 | 82910 | 79300976 |
Joint stiffness | 287.42 | 13.77 | 596 | 359906 | 40234 | 79343652 |
Agitation | 286.70 | 13.77 | 52 | 360450 | 99663 | 79284223 |
Drug eruption | 285.77 | 13.77 | 621 | 359881 | 43314 | 79340572 |
Therapeutic response decreased | 285.23 | 13.77 | 804 | 359698 | 66049 | 79317837 |
Neutrophil count decreased | 283.48 | 13.77 | 43 | 360459 | 93916 | 79289970 |
Granuloma skin | 283.00 | 13.77 | 273 | 360229 | 8901 | 79374985 |
Blood parathyroid hormone decreased | 279.77 | 13.77 | 289 | 360213 | 10247 | 79373639 |
Cardiac failure congestive | 278.52 | 13.77 | 148 | 360354 | 142254 | 79241632 |
Gastrointestinal haemorrhage | 276.70 | 13.77 | 162 | 360340 | 147557 | 79236329 |
Nasopharyngitis | 275.85 | 13.77 | 2029 | 358473 | 251852 | 79132034 |
Swollen joint count increased | 272.88 | 13.77 | 421 | 360081 | 22506 | 79361380 |
Cerebrovascular accident | 272.02 | 13.77 | 184 | 360318 | 155108 | 79228778 |
Metabolic acidosis | 270.17 | 13.77 | 29 | 360473 | 82500 | 79301386 |
Product dose omission issue | 268.97 | 13.77 | 440 | 360062 | 247097 | 79136789 |
Hallucination | 266.25 | 13.77 | 36 | 360466 | 85709 | 79298177 |
Cardiac failure | 261.29 | 13.77 | 191 | 360311 | 154651 | 79229235 |
Pneumonia aspiration | 258.76 | 13.77 | 10 | 360492 | 66957 | 79316929 |
Hypoxia | 258.51 | 13.77 | 73 | 360429 | 103170 | 79280716 |
Panniculitis | 256.58 | 13.77 | 298 | 360204 | 12073 | 79371813 |
Syncope | 253.54 | 13.77 | 262 | 360240 | 179187 | 79204699 |
Lactic acidosis | 248.50 | 13.77 | 18 | 360484 | 70341 | 79313545 |
International normalised ratio increased | 246.13 | 13.77 | 43 | 360459 | 84678 | 79299208 |
Pain in extremity | 244.46 | 13.77 | 2621 | 357881 | 361917 | 79021969 |
Mental status changes | 239.77 | 13.77 | 16 | 360486 | 66943 | 79316943 |
Pyrexia | 238.85 | 13.77 | 1944 | 358558 | 676765 | 78707121 |
Vision blurred | 236.86 | 13.77 | 91 | 360411 | 105807 | 79278079 |
Abdominal pain | 230.02 | 13.77 | 943 | 359559 | 388626 | 78995260 |
Pulmonary fibrosis | 228.24 | 13.77 | 570 | 359932 | 43542 | 79340344 |
Grip strength decreased | 223.91 | 13.77 | 375 | 360127 | 21494 | 79362392 |
Respiratory arrest | 220.98 | 13.77 | 9 | 360493 | 57541 | 79326345 |
Coma | 217.73 | 13.77 | 91 | 360411 | 100558 | 79283328 |
Neoplasm progression | 217.65 | 13.77 | 3 | 360499 | 51679 | 79332207 |
Unresponsive to stimuli | 216.68 | 13.77 | 8 | 360494 | 55780 | 79328106 |
Urinary tract infection | 216.64 | 13.77 | 585 | 359917 | 273927 | 79109959 |
Hyperglycaemia | 214.91 | 13.77 | 31 | 360471 | 70304 | 79313582 |
Sedation | 214.39 | 13.77 | 4 | 360498 | 51891 | 79331995 |
Chest discomfort | 209.56 | 13.77 | 189 | 360313 | 137855 | 79246031 |
Adverse drug reaction | 209.51 | 13.77 | 719 | 359783 | 65673 | 79318213 |
Nodule | 208.90 | 13.77 | 374 | 360128 | 22620 | 79361266 |
Multiple organ dysfunction syndrome | 207.21 | 13.77 | 145 | 360357 | 120101 | 79263785 |
Rheumatoid lung | 204.93 | 13.77 | 163 | 360339 | 4082 | 79379804 |
Finger deformity | 202.04 | 13.77 | 207 | 360295 | 7267 | 79376619 |
Musculoskeletal pain | 200.05 | 13.77 | 955 | 359547 | 101399 | 79282487 |
Oedema peripheral | 195.79 | 13.77 | 542 | 359960 | 251746 | 79132140 |
Cognitive disorder | 195.61 | 13.77 | 39 | 360463 | 69887 | 79313999 |
Pulmonary embolism | 194.07 | 13.77 | 297 | 360205 | 171357 | 79212529 |
Blood glucose increased | 193.72 | 13.77 | 142 | 360360 | 114833 | 79269053 |
Intentional product misuse | 193.40 | 13.77 | 94 | 360408 | 95071 | 79288815 |
Plasma cell myeloma | 192.85 | 13.77 | 12 | 360490 | 53247 | 79330639 |
Enthesopathy | 192.80 | 13.77 | 250 | 360252 | 11358 | 79372528 |
Vomiting | 191.80 | 13.77 | 2005 | 358497 | 663823 | 78720063 |
Balance disorder | 191.44 | 13.77 | 104 | 360398 | 98753 | 79285133 |
COVID-19 | 185.87 | 13.77 | 265 | 360237 | 157409 | 79226477 |
Dysarthria | 184.45 | 13.77 | 40 | 360462 | 67582 | 79316304 |
Serotonin syndrome | 183.89 | 13.77 | 4 | 360498 | 45023 | 79338863 |
Anxiety | 183.23 | 13.77 | 547 | 359955 | 247965 | 79135921 |
Chest pain | 180.87 | 13.77 | 661 | 359841 | 281643 | 79102243 |
Urinary retention | 180.09 | 13.77 | 22 | 360480 | 56608 | 79327278 |
Aggression | 180.06 | 13.77 | 13 | 360489 | 50945 | 79332941 |
Renal failure | 178.28 | 13.77 | 403 | 360099 | 200565 | 79183321 |
Decreased appetite | 174.44 | 13.77 | 875 | 359627 | 341543 | 79042343 |
Skin ulcer | 173.98 | 13.77 | 590 | 359912 | 53560 | 79330326 |
Ascites | 173.90 | 13.77 | 62 | 360440 | 75500 | 79308386 |
Pancytopenia | 173.14 | 13.77 | 302 | 360200 | 165443 | 79218443 |
Blood pressure decreased | 171.29 | 13.77 | 120 | 360382 | 99346 | 79284540 |
Orthostatic hypotension | 171.02 | 13.77 | 25 | 360477 | 56139 | 79327747 |
Respiratory distress | 170.79 | 13.77 | 29 | 360473 | 58310 | 79325576 |
Cerebral haemorrhage | 170.32 | 13.77 | 28 | 360474 | 57645 | 79326241 |
Loss of consciousness | 170.04 | 13.77 | 312 | 360190 | 167631 | 79216255 |
Hyperhidrosis | 169.44 | 13.77 | 264 | 360238 | 151228 | 79232658 |
Apparent death | 166.84 | 13.77 | 123 | 360379 | 2742 | 79381144 |
Blood creatine phosphokinase increased | 166.80 | 13.77 | 46 | 360456 | 66044 | 79317842 |
Sciatica | 166.34 | 13.77 | 424 | 360078 | 32798 | 79351088 |
White blood cell count decreased | 165.86 | 13.77 | 379 | 360123 | 187909 | 79195977 |
Deformity | 164.45 | 13.77 | 210 | 360292 | 9395 | 79374491 |
Dysphagia | 163.95 | 13.77 | 186 | 360316 | 121950 | 79261936 |
Pleural effusion | 163.56 | 13.77 | 252 | 360250 | 145010 | 79238876 |
Myalgia | 163.25 | 13.77 | 374 | 360128 | 185267 | 79198619 |
Pulmonary oedema | 160.72 | 13.77 | 100 | 360402 | 88154 | 79295732 |
Hypomagnesaemia | 160.08 | 13.77 | 14 | 360488 | 46897 | 79336989 |
Lethargy | 159.63 | 13.77 | 84 | 360418 | 81208 | 79302678 |
Rheumatoid factor negative | 158.92 | 13.77 | 86 | 360416 | 1087 | 79382799 |
Dislocation of vertebra | 158.72 | 13.77 | 187 | 360315 | 7693 | 79376193 |
Drug reaction with eosinophilia and systemic symptoms | 157.91 | 13.77 | 47 | 360455 | 64197 | 79319689 |
Disorientation | 157.85 | 13.77 | 44 | 360458 | 62732 | 79321154 |
Liver function test increased | 157.70 | 13.77 | 466 | 360036 | 39307 | 79344579 |
Asthenia | 157.07 | 13.77 | 1517 | 358985 | 510172 | 78873714 |
Haematuria | 155.84 | 13.77 | 58 | 360444 | 68778 | 79315108 |
Restlessness | 155.63 | 13.77 | 15 | 360487 | 46477 | 79337409 |
Skin necrosis | 155.19 | 13.77 | 287 | 360215 | 17800 | 79366086 |
Melaena | 154.38 | 13.77 | 42 | 360460 | 60848 | 79323038 |
Encephalopathy | 153.91 | 13.77 | 56 | 360446 | 67341 | 79316545 |
Impaired work ability | 153.67 | 13.77 | 300 | 360202 | 19381 | 79364505 |
Chills | 152.36 | 13.77 | 309 | 360193 | 159925 | 79223961 |
Blood creatinine increased | 149.15 | 13.77 | 297 | 360205 | 154760 | 79229126 |
Septic shock | 148.10 | 13.77 | 203 | 360299 | 122598 | 79261288 |
Sleep disorder | 148.00 | 13.77 | 772 | 359730 | 84905 | 79298981 |
Haemorrhage | 147.78 | 13.77 | 117 | 360385 | 91001 | 79292885 |
Renal impairment | 147.71 | 13.77 | 307 | 360195 | 157476 | 79226410 |
Hypervolaemia | 147.70 | 13.77 | 12 | 360490 | 42678 | 79341208 |
Disturbance in attention | 147.07 | 13.77 | 26 | 360476 | 50775 | 79333111 |
Wrong technique in product usage process | 147.04 | 13.77 | 75 | 360427 | 73800 | 79310086 |
Type 2 diabetes mellitus | 144.47 | 13.77 | 576 | 359926 | 56546 | 79327340 |
Limb deformity | 144.39 | 13.77 | 124 | 360378 | 3466 | 79380420 |
Ulcer | 143.34 | 13.77 | 376 | 360126 | 29596 | 79354290 |
Abnormal behaviour | 142.21 | 13.77 | 5 | 360497 | 36416 | 79347470 |
Acute myocardial infarction | 142.07 | 13.77 | 86 | 360416 | 76950 | 79306936 |
Tuberculin test positive | 141.75 | 13.77 | 120 | 360382 | 3288 | 79380598 |
Joint effusion | 141.15 | 13.77 | 275 | 360227 | 17739 | 79366147 |
Pancreatitis acute | 140.14 | 13.77 | 27 | 360475 | 49577 | 79334309 |
Ankylosing spondylitis | 139.50 | 13.77 | 220 | 360282 | 11985 | 79371901 |
Pneumonia | 138.50 | 13.77 | 2126 | 358376 | 658120 | 78725766 |
Night sweats | 137.97 | 13.77 | 533 | 359969 | 51562 | 79332324 |
Urticaria | 136.91 | 13.77 | 1359 | 359143 | 183842 | 79200044 |
Palmar-plantar erythrodysaesthesia syndrome | 135.09 | 13.77 | 3 | 360499 | 33131 | 79350755 |
Altered state of consciousness | 134.61 | 13.77 | 19 | 360483 | 43803 | 79340083 |
Rectal haemorrhage | 134.10 | 13.77 | 90 | 360412 | 76210 | 79307676 |
Ventricular tachycardia | 134.06 | 13.77 | 16 | 360486 | 41919 | 79341967 |
Intentional self-injury | 131.92 | 13.77 | 3 | 360499 | 32416 | 79351470 |
Flushing | 131.39 | 13.77 | 123 | 360379 | 88145 | 79295741 |
Joint destruction | 130.09 | 13.77 | 147 | 360355 | 5778 | 79378108 |
Oral mucosal exfoliation | 129.94 | 13.77 | 82 | 360420 | 1403 | 79382483 |
Generalised tonic-clonic seizure | 128.15 | 13.77 | 22 | 360480 | 43888 | 79339998 |
Alanine aminotransferase abnormal | 127.47 | 13.77 | 178 | 360324 | 8689 | 79375197 |
Haematoma | 126.81 | 13.77 | 39 | 360463 | 52156 | 79331730 |
Coronary artery disease | 126.58 | 13.77 | 69 | 360433 | 65405 | 79318481 |
Hallucination, visual | 126.05 | 13.77 | 5 | 360497 | 32724 | 79351162 |
Seronegative arthritis | 125.11 | 13.77 | 129 | 360373 | 4563 | 79379323 |
Haemoglobin decreased | 124.55 | 13.77 | 548 | 359954 | 221571 | 79162315 |
Toxic epidermal necrolysis | 122.34 | 13.77 | 26 | 360476 | 44555 | 79339331 |
Acute respiratory failure | 122.21 | 13.77 | 58 | 360444 | 59483 | 79324403 |
Joint injury | 122.20 | 13.77 | 365 | 360137 | 30970 | 79352916 |
Psychotic disorder | 120.27 | 13.77 | 21 | 360481 | 41381 | 79342505 |
Neuropathy peripheral | 119.95 | 13.77 | 290 | 360212 | 141015 | 79242871 |
Joint laxity | 119.61 | 13.77 | 93 | 360409 | 2251 | 79381635 |
Haematochezia | 119.23 | 13.77 | 132 | 360370 | 87513 | 79296373 |
Lymphocyte count decreased | 119.17 | 13.77 | 33 | 360469 | 47256 | 79336630 |
Musculoskeletal deformity | 119.12 | 13.77 | 79 | 360423 | 1477 | 79382409 |
Cerebral infarction | 118.66 | 13.77 | 30 | 360472 | 45646 | 79338240 |
Dyspnoea exertional | 117.50 | 13.77 | 132 | 360370 | 86941 | 79296945 |
Haemoptysis | 117.34 | 13.77 | 53 | 360449 | 55946 | 79327940 |
Red blood cell sedimentation rate | 116.99 | 13.77 | 135 | 360367 | 5430 | 79378456 |
Dysgeusia | 116.89 | 13.77 | 56 | 360446 | 57121 | 79326765 |
Physical disability | 116.84 | 13.77 | 106 | 360396 | 3192 | 79380694 |
Drug withdrawal syndrome | 116.74 | 13.77 | 11 | 360491 | 34707 | 79349179 |
Abdominal distension | 116.07 | 13.77 | 228 | 360274 | 119422 | 79264464 |
Chronic kidney disease | 114.97 | 13.77 | 79 | 360423 | 66075 | 79317811 |
Arrhythmia | 113.55 | 13.77 | 68 | 360434 | 61204 | 79322682 |
Breast cancer stage III | 113.52 | 13.77 | 178 | 360324 | 9648 | 79374238 |
Drug level increased | 113.26 | 13.77 | 21 | 360481 | 39630 | 79344256 |
Accidental overdose | 112.98 | 13.77 | 21 | 360481 | 39560 | 79344326 |
Blood bilirubin increased | 111.28 | 13.77 | 82 | 360420 | 66150 | 79317736 |
Joint arthroplasty | 110.94 | 13.77 | 95 | 360407 | 2645 | 79381241 |
Liver injury | 110.40 | 13.77 | 528 | 359974 | 56086 | 79327800 |
Urinary incontinence | 109.95 | 13.77 | 25 | 360477 | 40884 | 79343002 |
Blood calcium decreased | 109.93 | 13.77 | 9 | 360493 | 31810 | 79352076 |
Cardiogenic shock | 109.91 | 13.77 | 27 | 360475 | 41887 | 79341999 |
Fluid retention | 109.03 | 13.77 | 93 | 360409 | 69716 | 79314170 |
Ejection fraction decreased | 108.56 | 13.77 | 14 | 360488 | 34563 | 79349323 |
Exostosis | 108.14 | 13.77 | 237 | 360265 | 16621 | 79367265 |
Aphasia | 108.11 | 13.77 | 38 | 360464 | 46694 | 79337192 |
Dyskinesia | 107.79 | 13.77 | 34 | 360468 | 44739 | 79339147 |
Pallor | 107.07 | 13.77 | 46 | 360456 | 50016 | 79333870 |
Subdural haematoma | 105.59 | 13.77 | 10 | 360492 | 31424 | 79352462 |
Circulatory collapse | 105.37 | 13.77 | 21 | 360481 | 37647 | 79346239 |
Adverse reaction | 105.22 | 13.77 | 167 | 360335 | 9147 | 79374739 |
Inappropriate antidiuretic hormone secretion | 104.93 | 13.77 | 3 | 360499 | 26310 | 79357576 |
Gastric disorder | 104.91 | 13.77 | 390 | 360112 | 37043 | 79346843 |
Contusion | 104.77 | 13.77 | 1081 | 359421 | 147695 | 79236191 |
Wrist deformity | 101.58 | 13.77 | 81 | 360421 | 2036 | 79381850 |
Ear pain | 101.09 | 13.77 | 353 | 360149 | 32516 | 79351370 |
Dysuria | 100.99 | 13.77 | 52 | 360450 | 50899 | 79332987 |
Intentional product use issue | 100.91 | 13.77 | 1092 | 359410 | 151020 | 79232866 |
Labelled drug-drug interaction medication error | 100.80 | 13.77 | 6 | 360496 | 27644 | 79356242 |
Bone swelling | 100.74 | 13.77 | 74 | 360428 | 1640 | 79382246 |
Chronic obstructive pulmonary disease | 100.19 | 13.77 | 144 | 360358 | 85275 | 79298611 |
Blood urea increased | 99.41 | 13.77 | 48 | 360454 | 48742 | 79335144 |
Clostridium difficile colitis | 99.15 | 13.77 | 14 | 360488 | 32269 | 79351617 |
Femur fracture | 98.73 | 13.77 | 391 | 360111 | 38261 | 79345625 |
Sinus tachycardia | 98.30 | 13.77 | 23 | 360479 | 36885 | 79347001 |
Diabetic ketoacidosis | 97.61 | 13.77 | 18 | 360484 | 34104 | 79349782 |
Poisoning | 96.86 | 13.77 | 4 | 360498 | 25268 | 79358618 |
Sinus bradycardia | 96.75 | 13.77 | 4 | 360498 | 25243 | 79358643 |
Cholestasis | 96.32 | 13.77 | 58 | 360444 | 52051 | 79331835 |
Arthrodesis | 94.50 | 13.77 | 82 | 360420 | 2325 | 79381561 |
Tumour lysis syndrome | 94.48 | 13.77 | 3 | 360499 | 23936 | 79359950 |
Foot operation | 94.48 | 13.77 | 123 | 360379 | 5610 | 79378276 |
Transient ischaemic attack | 94.16 | 13.77 | 61 | 360441 | 52634 | 79331252 |
Full blood count abnormal | 93.48 | 13.77 | 33 | 360469 | 40441 | 79343445 |
Dry skin | 92.93 | 13.77 | 102 | 360400 | 67893 | 79315993 |
Neutropenic sepsis | 92.55 | 13.77 | 8 | 360494 | 27056 | 79356830 |
Loose body in joint | 92.54 | 13.77 | 63 | 360439 | 1232 | 79382654 |
Respiratory depression | 92.25 | 13.77 | 9 | 360493 | 27621 | 79356265 |
Upper gastrointestinal haemorrhage | 91.77 | 13.77 | 36 | 360466 | 41344 | 79342542 |
Haemorrhage intracranial | 91.63 | 13.77 | 7 | 360495 | 26186 | 79357700 |
Full blood count decreased | 91.51 | 13.77 | 8 | 360494 | 26811 | 79357075 |
Ventricular fibrillation | 90.99 | 13.77 | 17 | 360485 | 31909 | 79351977 |
Hepatic enzyme abnormal | 90.95 | 13.77 | 142 | 360360 | 7668 | 79376218 |
Diverticulitis | 90.71 | 13.77 | 430 | 360072 | 45506 | 79338380 |
Cough | 90.65 | 13.77 | 1142 | 359360 | 365647 | 79018239 |
Angioedema | 90.35 | 13.77 | 127 | 360375 | 75908 | 79307978 |
Deep vein thrombosis | 89.88 | 13.77 | 265 | 360237 | 120654 | 79263232 |
Cardiac disorder | 89.47 | 13.77 | 99 | 360403 | 65658 | 79318228 |
Withdrawal syndrome | 89 | 13.77 | 9 | 360493 | 26845 | 79357041 |
Premature delivery | 88.99 | 13.77 | 4 | 360498 | 23463 | 79360423 |
Surgical failure | 88.84 | 13.77 | 53 | 360449 | 816 | 79383070 |
Tendonitis | 87.69 | 13.77 | 272 | 360230 | 23558 | 79360328 |
Hypocalcaemia | 87.57 | 13.77 | 59 | 360443 | 49865 | 79334021 |
Basal cell carcinoma | 87.47 | 13.77 | 368 | 360134 | 37007 | 79346879 |
Presyncope | 87.36 | 13.77 | 38 | 360464 | 41016 | 79342870 |
Eosinophilia | 87.34 | 13.77 | 48 | 360454 | 45297 | 79338589 |
Suicidal ideation | 87.28 | 13.77 | 131 | 360371 | 76209 | 79307677 |
Acute myeloid leukaemia | 86.85 | 13.77 | 17 | 360485 | 30868 | 79353018 |
Anti-cyclic citrullinated peptide antibody | 86.40 | 13.77 | 119 | 360383 | 5733 | 79378153 |
Ileus | 86.31 | 13.77 | 9 | 360493 | 26202 | 79357684 |
Depressed mood | 85.44 | 13.77 | 57 | 360445 | 48423 | 79335463 |
Shoulder arthroplasty | 85.29 | 13.77 | 89 | 360413 | 3193 | 79380693 |
Mucosal inflammation | 85.15 | 13.77 | 131 | 360371 | 75449 | 79308437 |
Gait inability | 85.15 | 13.77 | 506 | 359996 | 58411 | 79325475 |
Myoclonus | 84.94 | 13.77 | 12 | 360490 | 27648 | 79356238 |
Pericardial effusion | 84.72 | 13.77 | 52 | 360450 | 46185 | 79337701 |
Irritability | 84.56 | 13.77 | 40 | 360462 | 41104 | 79342782 |
Fatigue | 84.32 | 13.77 | 5067 | 355435 | 924660 | 78459226 |
Limb discomfort | 83.65 | 13.77 | 332 | 360170 | 32518 | 79351368 |
Blood potassium decreased | 82.89 | 13.77 | 54 | 360448 | 46458 | 79337428 |
Bone pain | 82.57 | 13.77 | 78 | 360424 | 55664 | 79328222 |
Bacteraemia | 82.53 | 13.77 | 23 | 360479 | 32801 | 79351085 |
Fine motor skill dysfunction | 82.22 | 13.77 | 111 | 360391 | 5246 | 79378640 |
Haematemesis | 81.16 | 13.77 | 70 | 360432 | 52194 | 79331692 |
Shock | 81.16 | 13.77 | 48 | 360454 | 43500 | 79340386 |
Obstructive airways disorder | 81.07 | 13.77 | 21 | 360481 | 31438 | 79352448 |
Small intestinal obstruction | 81.06 | 13.77 | 13 | 360489 | 27259 | 79356627 |
Product use in unapproved indication | 81.03 | 13.77 | 732 | 359770 | 249627 | 79134259 |
Weight increased | 81.01 | 13.77 | 1730 | 358772 | 275656 | 79108230 |
Myocardial infarction | 80.80 | 13.77 | 494 | 360008 | 183635 | 79200251 |
Intestinal obstruction | 80.76 | 13.77 | 47 | 360455 | 42973 | 79340913 |
Product prescribing error | 79.90 | 13.77 | 52 | 360450 | 44761 | 79339125 |
Hypothermia | 79.79 | 13.77 | 6 | 360496 | 22740 | 79361146 |
Atlantoaxial instability | 79.58 | 13.77 | 35 | 360467 | 270 | 79383616 |
Synovial cyst | 79.28 | 13.77 | 154 | 360348 | 9911 | 79373975 |
Hyperbilirubinaemia | 79.26 | 13.77 | 9 | 360493 | 24509 | 79359377 |
Tongue disorder | 79.13 | 13.77 | 187 | 360315 | 13788 | 79370098 |
Status epilepticus | 78.95 | 13.77 | 10 | 360492 | 25031 | 79358855 |
Product administration error | 78.80 | 13.77 | 23 | 360479 | 31823 | 79352063 |
Bursitis | 78.56 | 13.77 | 346 | 360156 | 35498 | 79348388 |
Exposure during pregnancy | 78.54 | 13.77 | 750 | 359752 | 100382 | 79283504 |
Mineral metabolism disorder | 78.07 | 13.77 | 35 | 360467 | 284 | 79383602 |
Agranulocytosis | 77.94 | 13.77 | 54 | 360448 | 44976 | 79338910 |
Epilepsy | 77.62 | 13.77 | 44 | 360458 | 40816 | 79343070 |
Dementia | 77.38 | 13.77 | 10 | 360492 | 24649 | 79359237 |
Lower limb fracture | 77.26 | 13.77 | 256 | 360246 | 22959 | 79360927 |
Intestinal sepsis | 77.06 | 13.77 | 49 | 360453 | 850 | 79383036 |
Therapy non-responder | 76.94 | 13.77 | 695 | 359807 | 91610 | 79292276 |
Dystonia | 76.94 | 13.77 | 5 | 360497 | 21394 | 79362492 |
Leukocytosis | 76.70 | 13.77 | 51 | 360451 | 43404 | 79340482 |
X-ray abnormal | 76.66 | 13.77 | 112 | 360390 | 5701 | 79378185 |
Drug use disorder | 76.39 | 13.77 | 139 | 360363 | 8512 | 79375374 |
Retinitis | 76.27 | 13.77 | 110 | 360392 | 5533 | 79378353 |
Blood iron abnormal | 75.82 | 13.77 | 57 | 360445 | 1310 | 79382576 |
Head injury | 75.77 | 13.77 | 37 | 360465 | 37332 | 79346554 |
Hospitalisation | 75.61 | 13.77 | 199 | 360303 | 94037 | 79289849 |
Oxygen saturation decreased | 75.60 | 13.77 | 313 | 360189 | 128734 | 79255152 |
Hepatic encephalopathy | 75.35 | 13.77 | 10 | 360492 | 24156 | 79359730 |
Blood sodium decreased | 75.30 | 13.77 | 28 | 360474 | 33227 | 79350659 |
Bone marrow failure | 75.13 | 13.77 | 72 | 360430 | 51035 | 79332851 |
Pancreatitis | 74.28 | 13.77 | 122 | 360380 | 68453 | 79315433 |
Torsade de pointes | 74.20 | 13.77 | 3 | 360499 | 19309 | 79364577 |
Metastases to bone | 74.07 | 13.77 | 11 | 360491 | 24416 | 79359470 |
Therapy cessation | 73.46 | 13.77 | 39 | 360463 | 37523 | 79346363 |
Disseminated intravascular coagulation | 73.42 | 13.77 | 35 | 360467 | 35807 | 79348079 |
Bone cyst | 73.38 | 13.77 | 84 | 360418 | 3349 | 79380537 |
Sensitivity to weather change | 73.23 | 13.77 | 131 | 360371 | 7916 | 79375970 |
Creatinine renal clearance decreased | 72.85 | 13.77 | 3 | 360499 | 18999 | 79364887 |
Metastases to liver | 72.77 | 13.77 | 19 | 360483 | 28295 | 79355591 |
Pulmonary hypertension | 72.72 | 13.77 | 66 | 360436 | 48014 | 79335872 |
Lupus-like syndrome | 72.65 | 13.77 | 180 | 360322 | 13677 | 79370209 |
Tachypnoea | 72.59 | 13.77 | 27 | 360475 | 32036 | 79351850 |
Deep vein thrombosis postoperative | 72.21 | 13.77 | 154 | 360348 | 10598 | 79373288 |
Bone disorder | 72.04 | 13.77 | 220 | 360282 | 18893 | 79364993 |
Stevens-Johnson syndrome | 71.82 | 13.77 | 44 | 360458 | 39122 | 79344764 |
Ankle deformity | 71.69 | 13.77 | 43 | 360459 | 669 | 79383217 |
Flatulence | 71.63 | 13.77 | 53 | 360449 | 42671 | 79341215 |
Muscle spasticity | 71.63 | 13.77 | 237 | 360265 | 21238 | 79362648 |
Aspiration | 71.63 | 13.77 | 5 | 360497 | 20153 | 79363733 |
Device dislocation | 71.55 | 13.77 | 15 | 360487 | 25955 | 79357931 |
Hallucination, auditory | 71.08 | 13.77 | 6 | 360496 | 20687 | 79363199 |
Hemiparesis | 70.55 | 13.77 | 32 | 360470 | 33701 | 79350185 |
Adjustment disorder with depressed mood | 70.32 | 13.77 | 138 | 360364 | 8948 | 79374938 |
Systemic lupus erythematosus rash | 70.28 | 13.77 | 62 | 360440 | 1798 | 79382088 |
Deafness transitory | 70.14 | 13.77 | 48 | 360454 | 947 | 79382939 |
Rash erythematous | 70.13 | 13.77 | 95 | 360407 | 57674 | 79326212 |
Terminal state | 70.06 | 13.77 | 98 | 360404 | 4791 | 79379095 |
Mitral valve incompetence | 70.01 | 13.77 | 21 | 360481 | 28544 | 79355342 |
Intervertebral disc space narrowing | 69.93 | 13.77 | 60 | 360442 | 1675 | 79382211 |
Mania | 69.61 | 13.77 | 3 | 360499 | 18257 | 79365629 |
Colitis | 69.11 | 13.77 | 142 | 360360 | 73165 | 79310721 |
Palpitations | 68.74 | 13.77 | 316 | 360186 | 126294 | 79257592 |
Cholelithiasis | 68.71 | 13.77 | 82 | 360420 | 52582 | 79331304 |
Thyroid neoplasm | 68.61 | 13.77 | 78 | 360424 | 3086 | 79380800 |
Multiple fractures | 68.40 | 13.77 | 127 | 360375 | 7899 | 79375987 |
Psoriasis | 68.39 | 13.77 | 662 | 359840 | 88925 | 79294961 |
Abdominal pain lower | 68.29 | 13.77 | 29 | 360473 | 31753 | 79352133 |
Facet joint syndrome | 68.12 | 13.77 | 155 | 360347 | 11147 | 79372739 |
Myopathy | 67.87 | 13.77 | 7 | 360495 | 20556 | 79363330 |
Hypophosphataemia | 67.78 | 13.77 | 6 | 360496 | 19907 | 79363979 |
Joint dislocation | 67.65 | 13.77 | 199 | 360303 | 16740 | 79367146 |
Bone density abnormal | 67.32 | 13.77 | 76 | 360426 | 2984 | 79380902 |
Pollakiuria | 66.94 | 13.77 | 43 | 360459 | 37274 | 79346612 |
Spinal instability | 66.47 | 13.77 | 35 | 360467 | 417 | 79383469 |
Renal tubular necrosis | 65.90 | 13.77 | 16 | 360486 | 25023 | 79358863 |
Drug ineffective for unapproved indication | 65.56 | 13.77 | 81 | 360421 | 51157 | 79332729 |
Coordination abnormal | 65.49 | 13.77 | 3 | 360499 | 17309 | 79366577 |
Muscle rigidity | 65.02 | 13.77 | 7 | 360495 | 19875 | 79364011 |
Gastrooesophageal reflux disease | 64.77 | 13.77 | 247 | 360255 | 103999 | 79279887 |
International normalised ratio fluctuation | 64.70 | 13.77 | 79 | 360423 | 3375 | 79380511 |
Anuria | 64.59 | 13.77 | 9 | 360493 | 20954 | 79362932 |
Infusion site reaction | 63.99 | 13.77 | 79 | 360423 | 3414 | 79380472 |
Therapy interrupted | 63.59 | 13.77 | 31 | 360471 | 31310 | 79352576 |
Electrolyte imbalance | 63.49 | 13.77 | 30 | 360472 | 30851 | 79353035 |
Tinnitus | 63.39 | 13.77 | 64 | 360438 | 44269 | 79339617 |
Tubulointerstitial nephritis | 63.37 | 13.77 | 48 | 360454 | 38187 | 79345699 |
Muscle twitching | 62.92 | 13.77 | 17 | 360485 | 24747 | 79359139 |
Extrapyramidal disorder | 62.69 | 13.77 | 13 | 360489 | 22666 | 79361220 |
Haemodynamic instability | 62.68 | 13.77 | 4 | 360498 | 17378 | 79366508 |
Polyarthritis | 62.39 | 13.77 | 157 | 360345 | 12045 | 79371841 |
Heart rate increased | 62.21 | 13.77 | 307 | 360195 | 120417 | 79263469 |
Acidosis | 62.04 | 13.77 | 8 | 360494 | 19754 | 79364132 |
Wound infection | 61.51 | 13.77 | 243 | 360259 | 23748 | 79360138 |
Gastritis | 61.27 | 13.77 | 76 | 360426 | 47917 | 79335969 |
Toxic skin eruption | 61.17 | 13.77 | 13 | 360489 | 22280 | 79361606 |
Neck deformity | 61.10 | 13.77 | 57 | 360445 | 1780 | 79382106 |
Mydriasis | 60.92 | 13.77 | 5 | 360497 | 17638 | 79366248 |
Lip swelling | 60.88 | 13.77 | 57 | 360445 | 40854 | 79343032 |
Diarrhoea | 60.75 | 13.77 | 3309 | 357193 | 877180 | 78506706 |
Atrial flutter | 60.60 | 13.77 | 12 | 360490 | 21613 | 79362273 |
Visual acuity reduced | 60.02 | 13.77 | 29 | 360473 | 29440 | 79354446 |
Bloody discharge | 60.01 | 13.77 | 58 | 360444 | 1895 | 79381991 |
Electrocardiogram abnormal | 59.91 | 13.77 | 4 | 360498 | 16733 | 79367153 |
Hepatic failure | 59.91 | 13.77 | 116 | 360386 | 61096 | 79322790 |
Injection site reaction | 59.44 | 13.77 | 438 | 360064 | 54347 | 79329539 |
Retinal toxicity | 59.33 | 13.77 | 50 | 360452 | 1361 | 79382525 |
Cyanosis | 59.07 | 13.77 | 20 | 360482 | 25162 | 79358724 |
White blood cell count increased | 58.82 | 13.77 | 159 | 360343 | 74474 | 79309412 |
Onychomycosis | 58.60 | 13.77 | 121 | 360381 | 8140 | 79375746 |
Diplopia | 58.10 | 13.77 | 40 | 360462 | 33426 | 79350460 |
Peritonitis | 58.01 | 13.77 | 27 | 360475 | 28009 | 79355877 |
Hepatic cytolysis | 57.98 | 13.77 | 25 | 360477 | 27126 | 79356760 |
Spinal column injury | 57.83 | 13.77 | 60 | 360442 | 2138 | 79381748 |
Device issue | 57.82 | 13.77 | 25 | 360477 | 27083 | 79356803 |
Lip dry | 57.67 | 13.77 | 177 | 360325 | 15241 | 79368645 |
Transfusion | 57.39 | 13.77 | 13 | 360489 | 21317 | 79362569 |
Lower gastrointestinal haemorrhage | 57.29 | 13.77 | 4 | 360498 | 16121 | 79367765 |
Investigation abnormal | 57.26 | 13.77 | 58 | 360444 | 2008 | 79381878 |
Supraventricular tachycardia | 57.15 | 13.77 | 13 | 360489 | 21257 | 79362629 |
Angina pectoris | 57 | 13.77 | 91 | 360411 | 51641 | 79332245 |
Ischaemic stroke | 56.98 | 13.77 | 40 | 360462 | 33091 | 79350795 |
Cellulitis | 56.97 | 13.77 | 276 | 360226 | 108784 | 79275102 |
Hypercholesterolaemia | 56.87 | 13.77 | 231 | 360271 | 22864 | 79361022 |
Face oedema | 56.83 | 13.77 | 28 | 360474 | 28108 | 79355778 |
Aplastic anaemia | 56.82 | 13.77 | 7 | 360495 | 17898 | 79365988 |
Hypophagia | 56.71 | 13.77 | 73 | 360429 | 45294 | 79338592 |
Acute generalised exanthematous pustulosis | 56.62 | 13.77 | 6 | 360496 | 17248 | 79366638 |
Cardiac failure acute | 56.31 | 13.77 | 9 | 360493 | 18920 | 79364966 |
Mouth ulceration | 56.28 | 13.77 | 331 | 360171 | 38063 | 79345823 |
Ovarian neoplasm | 56.12 | 13.77 | 35 | 360467 | 586 | 79383300 |
Fear | 56.04 | 13.77 | 15 | 360487 | 21971 | 79361915 |
Delusion | 55.85 | 13.77 | 12 | 360490 | 20411 | 79363475 |
Left ventricular dysfunction | 55.84 | 13.77 | 10 | 360492 | 19351 | 79364535 |
Drug tolerance | 55.69 | 13.77 | 122 | 360380 | 8553 | 79375333 |
Nausea | 55.61 | 13.77 | 3656 | 356846 | 953540 | 78430346 |
Anticipatory anxiety | 55.50 | 13.77 | 45 | 360457 | 1159 | 79382727 |
Product substitution issue | 55.19 | 13.77 | 12 | 360490 | 20244 | 79363642 |
Myocarditis | 55.07 | 13.77 | 15 | 360487 | 21718 | 79362168 |
Gastrointestinal pain | 54.85 | 13.77 | 131 | 360371 | 9724 | 79374162 |
Dactylitis | 54.82 | 13.77 | 65 | 360437 | 2692 | 79381194 |
Subarachnoid haemorrhage | 54.72 | 13.77 | 21 | 360481 | 24444 | 79359442 |
Acute coronary syndrome | 54.66 | 13.77 | 14 | 360488 | 21119 | 79362767 |
Product quality issue | 54.49 | 13.77 | 44 | 360458 | 33896 | 79349990 |
Delirium | 54.21 | 13.77 | 198 | 360304 | 84429 | 79299457 |
Mycobacterium tuberculosis complex test positive | 54.16 | 13.77 | 65 | 360437 | 2727 | 79381159 |
Atrioventricular block complete | 53.93 | 13.77 | 6 | 360496 | 16604 | 79367282 |
Pruritus allergic | 53.60 | 13.77 | 47 | 360455 | 1352 | 79382534 |
Cardiomegaly | 53.57 | 13.77 | 26 | 360476 | 26326 | 79357560 |
Mental disorder | 53.56 | 13.77 | 38 | 360464 | 31264 | 79352622 |
Ataxia | 53.55 | 13.77 | 23 | 360479 | 25016 | 79358870 |
Asthma | 53.40 | 13.77 | 374 | 360128 | 134721 | 79249165 |
Haemodialysis | 53.24 | 13.77 | 9 | 360493 | 18159 | 79365727 |
Metastases to lung | 53.22 | 13.77 | 9 | 360493 | 18154 | 79365732 |
Metastases to central nervous system | 52.96 | 13.77 | 6 | 360496 | 16369 | 79367517 |
Renal injury | 52.79 | 13.77 | 7 | 360495 | 16920 | 79366966 |
Incorrect dose administered | 52.65 | 13.77 | 174 | 360328 | 76456 | 79307430 |
Malnutrition | 52.56 | 13.77 | 18 | 360484 | 22484 | 79361402 |
Spinal stenosis | 52.43 | 13.77 | 174 | 360328 | 15617 | 79368269 |
Body temperature increased | 52.17 | 13.77 | 362 | 360140 | 44058 | 79339828 |
Prescribed overdose | 51.96 | 13.77 | 321 | 360181 | 37562 | 79346324 |
Incontinence | 51.85 | 13.77 | 3 | 360499 | 14161 | 79369725 |
C-reactive protein | 51.79 | 13.77 | 86 | 360416 | 4893 | 79378993 |
Immune thrombocytopenia | 51.78 | 13.77 | 9 | 360493 | 17796 | 79366090 |
Osteosclerosis | 51.63 | 13.77 | 76 | 360426 | 3895 | 79379991 |
Hypoalbuminaemia | 51.57 | 13.77 | 16 | 360486 | 21281 | 79362605 |
Hyperthyroidism | 51.47 | 13.77 | 18 | 360484 | 22191 | 79361695 |
Prostate cancer | 51.11 | 13.77 | 45 | 360457 | 33223 | 79350663 |
Pemphigoid | 51.10 | 13.77 | 5 | 360497 | 15310 | 79368576 |
Vertigo | 50.88 | 13.77 | 152 | 360350 | 68930 | 79314956 |
Shock haemorrhagic | 50.54 | 13.77 | 14 | 360488 | 20046 | 79363840 |
Urine output decreased | 50.50 | 13.77 | 10 | 360492 | 18012 | 79365874 |
Joint space narrowing | 50.43 | 13.77 | 34 | 360468 | 654 | 79383232 |
Blood glucose decreased | 50.19 | 13.77 | 28 | 360474 | 26206 | 79357680 |
Fear of injection | 50.14 | 13.77 | 107 | 360395 | 7367 | 79376519 |
Localised infection | 50.05 | 13.77 | 316 | 360186 | 37259 | 79346627 |
Clostridium difficile infection | 50.01 | 13.77 | 72 | 360430 | 42613 | 79341273 |
Weight decreased | 49.95 | 13.77 | 1223 | 359279 | 353975 | 79029911 |
Maternal exposure timing unspecified | 49.80 | 13.77 | 92 | 360410 | 5700 | 79378186 |
Nocturia | 49.78 | 13.77 | 3 | 360499 | 13678 | 79370208 |
Sudden death | 49.24 | 13.77 | 20 | 360482 | 22491 | 79361395 |
Speech disorder | 49.19 | 13.77 | 108 | 360394 | 54337 | 79329549 |
Ventricular extrasystoles | 49.18 | 13.77 | 14 | 360488 | 19690 | 79364196 |
Arthritis bacterial | 49.04 | 13.77 | 120 | 360382 | 9046 | 79374840 |
Peripheral venous disease | 49.04 | 13.77 | 171 | 360331 | 15738 | 79368148 |
Nail disorder | 49.02 | 13.77 | 141 | 360361 | 11711 | 79372175 |
Haemorrhoids | 49.01 | 13.77 | 36 | 360466 | 29092 | 79354794 |
Red cell distribution width decreased | 48.95 | 13.77 | 53 | 360449 | 1985 | 79381901 |
Extremity contracture | 48.69 | 13.77 | 49 | 360453 | 1683 | 79382203 |
Device difficult to use | 48.50 | 13.77 | 3 | 360499 | 13382 | 79370504 |
Tuberculosis | 48.28 | 13.77 | 165 | 360337 | 15033 | 79368853 |
Emotional distress | 48.24 | 13.77 | 66 | 360436 | 39903 | 79343983 |
Acute respiratory distress syndrome | 48.10 | 13.77 | 78 | 360424 | 43989 | 79339897 |
Pulmonary toxicity | 48.07 | 13.77 | 148 | 360354 | 12766 | 79371120 |
Cytomegalovirus infection | 47.95 | 13.77 | 74 | 360428 | 42570 | 79341316 |
Chondropathy | 47.94 | 13.77 | 58 | 360444 | 2454 | 79381432 |
Polyomavirus-associated nephropathy | 47.91 | 13.77 | 89 | 360413 | 5538 | 79378348 |
Frequent bowel movements | 47.79 | 13.77 | 38 | 360464 | 29501 | 79354385 |
Nightmare | 47.49 | 13.77 | 29 | 360473 | 25832 | 79358054 |
Bronchitis chronic | 47.41 | 13.77 | 78 | 360424 | 4404 | 79379482 |
Device related infection | 47.35 | 13.77 | 51 | 360451 | 34243 | 79349643 |
Blood magnesium decreased | 46.61 | 13.77 | 9 | 360493 | 16503 | 79367383 |
Appendicitis | 46.26 | 13.77 | 18 | 360484 | 20776 | 79363110 |
Vascular access complication | 45.98 | 13.77 | 53 | 360449 | 2129 | 79381757 |
Oliguria | 45.81 | 13.77 | 9 | 360493 | 16300 | 79367586 |
Arteriosclerosis coronary artery | 45.70 | 13.77 | 12 | 360490 | 17804 | 79366082 |
Jaundice | 45.64 | 13.77 | 109 | 360393 | 53240 | 79330646 |
Myelodysplastic syndrome | 45.34 | 13.77 | 42 | 360460 | 30259 | 79353627 |
Secretion discharge | 45.04 | 13.77 | 160 | 360342 | 14862 | 79369024 |
Confusional state | 44.95 | 13.77 | 1094 | 359408 | 316903 | 79066983 |
Coagulopathy | 44.94 | 13.77 | 58 | 360444 | 35948 | 79347938 |
Mean platelet volume decreased | 44.64 | 13.77 | 59 | 360443 | 2731 | 79381155 |
Mycotic allergy | 44.60 | 13.77 | 44 | 360458 | 1475 | 79382411 |
Skin exfoliation | 44.47 | 13.77 | 116 | 360386 | 54984 | 79328902 |
Ankle arthroplasty | 44.45 | 13.77 | 44 | 360458 | 1481 | 79382405 |
Myelosuppression | 44.29 | 13.77 | 71 | 360431 | 40225 | 79343661 |
Vasculitic rash | 44.27 | 13.77 | 52 | 360450 | 2132 | 79381754 |
Colitis ischaemic | 44.15 | 13.77 | 8 | 360494 | 15351 | 79368535 |
Fracture delayed union | 44.04 | 13.77 | 51 | 360451 | 2059 | 79381827 |
Troponin increased | 43.95 | 13.77 | 16 | 360486 | 19239 | 79364647 |
Rash maculo-papular | 43.79 | 13.77 | 120 | 360382 | 55958 | 79327928 |
Hair follicle tumour benign | 43.77 | 13.77 | 27 | 360475 | 443 | 79383443 |
Gait disturbance | 43.65 | 13.77 | 1238 | 359264 | 206268 | 79177618 |
Myocardial ischaemia | 43.64 | 13.77 | 31 | 360471 | 25488 | 79358398 |
Erectile dysfunction | 43.56 | 13.77 | 7 | 360495 | 14657 | 79369229 |
Hypotonia | 43.48 | 13.77 | 4 | 360498 | 12866 | 79371020 |
Paraesthesia oral | 43.47 | 13.77 | 19 | 360483 | 20452 | 79363434 |
Panic attack | 43.31 | 13.77 | 28 | 360474 | 24188 | 79359698 |
Sleep apnoea syndrome | 43.26 | 13.77 | 61 | 360441 | 36417 | 79347469 |
Pulmonary thrombosis | 43.01 | 13.77 | 137 | 360365 | 12034 | 79371852 |
Lacrimation increased | 42.99 | 13.77 | 24 | 360478 | 22453 | 79361433 |
Wrist surgery | 42.96 | 13.77 | 33 | 360469 | 784 | 79383102 |
Faeces discoloured | 42.85 | 13.77 | 41 | 360461 | 29086 | 79354800 |
Accidental exposure to product | 42.78 | 13.77 | 47 | 360455 | 31275 | 79352611 |
Lymphopenia | 42.68 | 13.77 | 45 | 360457 | 30512 | 79353374 |
Inappropriate schedule of product administration | 42.63 | 13.77 | 392 | 360110 | 133236 | 79250650 |
Blood loss anaemia | 42.60 | 13.77 | 9 | 360493 | 15489 | 79368397 |
Neutrophil count increased | 42.52 | 13.77 | 42 | 360460 | 29354 | 79354532 |
Hepatocellular injury | 42.51 | 13.77 | 95 | 360407 | 47498 | 79336388 |
Drug level decreased | 42.50 | 13.77 | 7 | 360495 | 14395 | 79369491 |
Bronchopulmonary aspergillosis | 42.36 | 13.77 | 24 | 360478 | 22270 | 79361616 |
Oesophagitis | 42.20 | 13.77 | 29 | 360473 | 24260 | 79359626 |
Skin discolouration | 41.70 | 13.77 | 76 | 360426 | 40958 | 79342928 |
Granuloma | 41.64 | 13.77 | 106 | 360396 | 8191 | 79375695 |
Pulmonary haemorrhage | 41.59 | 13.77 | 8 | 360494 | 14709 | 79369177 |
Infusion site pain | 41.59 | 13.77 | 7 | 360495 | 14169 | 79369717 |
Autoimmune disorder | 41.58 | 13.77 | 167 | 360335 | 16445 | 79367441 |
Eosinophil count increased | 41.15 | 13.77 | 13 | 360489 | 17092 | 79366794 |
Atrioventricular block | 41.05 | 13.77 | 7 | 360495 | 14034 | 79369852 |
Injection site hypersensitivity | 40.97 | 13.77 | 47 | 360455 | 1878 | 79382008 |
Angina unstable | 40.77 | 13.77 | 12 | 360490 | 16515 | 79367371 |
Hepatotoxicity | 40.43 | 13.77 | 382 | 360120 | 50970 | 79332916 |
Prothrombin time prolonged | 40.38 | 13.77 | 13 | 360489 | 16886 | 79367000 |
Emotional disorder | 40.28 | 13.77 | 8 | 360494 | 14379 | 79369507 |
Thirst | 39.98 | 13.77 | 17 | 360485 | 18602 | 79365284 |
Incorrect product administration duration | 39.92 | 13.77 | 4 | 360498 | 12018 | 79371868 |
Mental impairment | 39.90 | 13.77 | 18 | 360484 | 19018 | 79364868 |
Osteoporotic fracture | 39.84 | 13.77 | 70 | 360432 | 4170 | 79379716 |
Live birth | 39.61 | 13.77 | 179 | 360323 | 18565 | 79365321 |
Paraesthesia | 39.48 | 13.77 | 560 | 359942 | 175763 | 79208123 |
Chromaturia | 39.34 | 13.77 | 35 | 360467 | 25711 | 79358175 |
Vaginal haemorrhage | 39.32 | 13.77 | 25 | 360477 | 21792 | 79362094 |
Cholecystitis | 39.29 | 13.77 | 26 | 360476 | 22186 | 79361700 |
Tricuspid valve incompetence | 39.24 | 13.77 | 20 | 360482 | 19692 | 79364194 |
Pneumonia fungal | 39.20 | 13.77 | 3 | 360499 | 11207 | 79372679 |
Failure to thrive | 39.17 | 13.77 | 4 | 360498 | 11840 | 79372046 |
Cardiomyopathy | 38.40 | 13.77 | 44 | 360458 | 28730 | 79355156 |
Feeling abnormal | 38.39 | 13.77 | 498 | 360004 | 158701 | 79225185 |
Burning sensation | 38.33 | 13.77 | 136 | 360366 | 58496 | 79325390 |
Mean cell volume decreased | 38.12 | 13.77 | 75 | 360427 | 4872 | 79379014 |
Respiratory disorder | 38.01 | 13.77 | 339 | 360163 | 44517 | 79339369 |
Liver disorder | 37.90 | 13.77 | 497 | 360005 | 71920 | 79311966 |
Dialysis | 37.86 | 13.77 | 18 | 360484 | 18444 | 79365442 |
Joint ankylosis | 37.85 | 13.77 | 48 | 360454 | 2132 | 79381754 |
Dysphonia | 37.79 | 13.77 | 131 | 360371 | 56741 | 79327145 |
Lyme disease | 37.75 | 13.77 | 60 | 360442 | 3290 | 79380596 |
Soft tissue swelling | 37.75 | 13.77 | 40 | 360462 | 1461 | 79382425 |
Cytology abnormal | 37.73 | 13.77 | 22 | 360480 | 324 | 79383562 |
Demyelination | 37.69 | 13.77 | 100 | 360402 | 7923 | 79375963 |
Acute pulmonary oedema | 37.63 | 13.77 | 9 | 360493 | 14221 | 79369665 |
Diastolic dysfunction | 37.51 | 13.77 | 3 | 360499 | 10808 | 79373078 |
Allergic oedema | 37.39 | 13.77 | 30 | 360472 | 761 | 79383125 |
Foot fracture | 37.20 | 13.77 | 197 | 360305 | 21784 | 79362102 |
Transaminases abnormal | 37.19 | 13.77 | 31 | 360471 | 831 | 79383055 |
Pulmonary arterial hypertension | 37.18 | 13.77 | 44 | 360458 | 28322 | 79355564 |
Coronary artery stenosis | 36.99 | 13.77 | 6 | 360496 | 12478 | 79371408 |
Bradyphrenia | 36.78 | 13.77 | 3 | 360499 | 10637 | 79373249 |
Hypertension | 36.71 | 13.77 | 1839 | 358663 | 329153 | 79054733 |
Brain oedema | 36.65 | 13.77 | 36 | 360466 | 25227 | 79358659 |
Mass excision | 36.64 | 13.77 | 22 | 360480 | 343 | 79383543 |
Labile blood pressure | 36.60 | 13.77 | 48 | 360454 | 2205 | 79381681 |
Bronchospasm | 36.56 | 13.77 | 35 | 360467 | 24824 | 79359062 |
Respiratory acidosis | 36.48 | 13.77 | 4 | 360498 | 11196 | 79372690 |
Epstein-Barr virus infection | 36.43 | 13.77 | 10 | 360492 | 14406 | 79369480 |
Atelectasis | 36.24 | 13.77 | 56 | 360446 | 32201 | 79351685 |
Infiltration anaesthesia | 36.03 | 13.77 | 17 | 360485 | 157 | 79383729 |
Hypercalcaemia | 36.01 | 13.77 | 297 | 360205 | 38133 | 79345753 |
Klebsiella infection | 35.99 | 13.77 | 13 | 360489 | 15707 | 79368179 |
Diabetes mellitus inadequate control | 35.87 | 13.77 | 34 | 360468 | 24230 | 79359656 |
Activated partial thromboplastin time prolonged | 35.71 | 13.77 | 10 | 360492 | 14218 | 79369668 |
Bladder cancer | 35.71 | 13.77 | 22 | 360480 | 19504 | 79364382 |
Salivary hypersecretion | 35.70 | 13.77 | 10 | 360492 | 14214 | 79369672 |
Herpes zoster | 35.50 | 13.77 | 605 | 359897 | 92478 | 79291408 |
Ear infection | 35.49 | 13.77 | 272 | 360230 | 34160 | 79349726 |
Hospice care | 35.44 | 13.77 | 3 | 360499 | 10321 | 79373565 |
Anal incontinence | 35.32 | 13.77 | 19 | 360483 | 18149 | 79365737 |
Epistaxis | 35.19 | 13.77 | 328 | 360174 | 111187 | 79272699 |
Pustular psoriasis | 34.80 | 13.77 | 71 | 360431 | 4735 | 79379151 |
Eye swelling | 34.75 | 13.77 | 41 | 360461 | 26427 | 79357459 |
Pulse absent | 34.51 | 13.77 | 3 | 360499 | 10100 | 79373786 |
Aspergillus infection | 34.48 | 13.77 | 22 | 360480 | 19139 | 79364747 |
Complication associated with device | 34.46 | 13.77 | 18 | 360484 | 17478 | 79366408 |
Impaired gastric emptying | 34.30 | 13.77 | 114 | 360388 | 10239 | 79373647 |
Hiccups | 34.20 | 13.77 | 3 | 360499 | 10028 | 79373858 |
Osteopenia | 34.16 | 13.77 | 169 | 360333 | 18195 | 79365691 |
Proteinuria | 34.11 | 13.77 | 59 | 360443 | 32443 | 79351443 |
Spinal fusion surgery | 34.00 | 13.77 | 74 | 360428 | 5164 | 79378722 |
Cutaneous vasculitis | 33.96 | 13.77 | 98 | 360404 | 8154 | 79375732 |
Asphyxia | 33.92 | 13.77 | 6 | 360496 | 11714 | 79372172 |
Hepatic cancer | 33.70 | 13.77 | 4 | 360498 | 10525 | 79373361 |
Skin papilloma | 33.58 | 13.77 | 79 | 360423 | 5807 | 79378079 |
Oropharyngeal pain | 33.50 | 13.77 | 324 | 360178 | 109029 | 79274857 |
Enteritis | 33.49 | 13.77 | 12 | 360490 | 14571 | 79369315 |
Polyuria | 33.39 | 13.77 | 13 | 360489 | 15001 | 79368885 |
Sarcoidosis | 33.36 | 13.77 | 98 | 360404 | 8237 | 79375649 |
Enterocolitis | 33.22 | 13.77 | 12 | 360490 | 14500 | 79369386 |
Hypermobility syndrome | 33.22 | 13.77 | 24 | 360478 | 518 | 79383368 |
Posterior reversible encephalopathy syndrome | 33.14 | 13.77 | 42 | 360460 | 26239 | 79357647 |
Purpura | 33.02 | 13.77 | 24 | 360478 | 19503 | 79364383 |
Embolism | 32.98 | 13.77 | 11 | 360491 | 13971 | 79369915 |
Enthesophyte | 32.81 | 13.77 | 12 | 360490 | 53 | 79383833 |
Apathy | 32.80 | 13.77 | 9 | 360493 | 12968 | 79370918 |
Eye pain | 32.76 | 13.77 | 76 | 360426 | 37502 | 79346384 |
Heparin-induced thrombocytopenia | 32.73 | 13.77 | 3 | 360499 | 9679 | 79374207 |
Hypothyroidism | 32.62 | 13.77 | 124 | 360378 | 52268 | 79331618 |
Hyperlipidaemia | 32.60 | 13.77 | 42 | 360460 | 26051 | 79357835 |
Swollen tongue | 32.56 | 13.77 | 92 | 360410 | 42478 | 79341408 |
Bunion operation | 32.56 | 13.77 | 30 | 360472 | 922 | 79382964 |
Ileus paralytic | 32.47 | 13.77 | 3 | 360499 | 9617 | 79374269 |
Neck pain | 32.43 | 13.77 | 500 | 360002 | 74917 | 79308969 |
General physical health deterioration | 32.34 | 13.77 | 1538 | 358964 | 273700 | 79110186 |
Tooth disorder | 32.12 | 13.77 | 216 | 360286 | 26017 | 79357869 |
Rash papular | 32.06 | 13.77 | 31 | 360471 | 21885 | 79362001 |
Sensory disturbance | 32.00 | 13.77 | 14 | 360488 | 15063 | 79368823 |
Feeling hot | 31.87 | 13.77 | 150 | 360352 | 59584 | 79324302 |
Respiratory syncytial virus infection | 31.55 | 13.77 | 3 | 360499 | 9399 | 79374487 |
Tardive dyskinesia | 31.50 | 13.77 | 5 | 360497 | 10566 | 79373320 |
Productive cough | 31.35 | 13.77 | 252 | 360250 | 88079 | 79295807 |
Joint lock | 31.29 | 13.77 | 54 | 360448 | 3171 | 79380715 |
Blindness | 31.20 | 13.77 | 50 | 360452 | 28333 | 79355553 |
Tendon disorder | 31.19 | 13.77 | 87 | 360415 | 7099 | 79376787 |
Latent tuberculosis | 31.05 | 13.77 | 55 | 360447 | 3298 | 79380588 |
Brain injury | 31.02 | 13.77 | 7 | 360495 | 11510 | 79372376 |
Bundle branch block left | 31.01 | 13.77 | 7 | 360495 | 11506 | 79372380 |
Hepatitis cholestatic | 30.80 | 13.77 | 12 | 360490 | 13840 | 79370046 |
Psychomotor hyperactivity | 30.79 | 13.77 | 19 | 360483 | 16830 | 79367056 |
Swelling face | 30.72 | 13.77 | 192 | 360310 | 71020 | 79312866 |
Central nervous system lesion | 30.70 | 13.77 | 11 | 360491 | 13357 | 79370529 |
Eructation | 30.68 | 13.77 | 6 | 360496 | 10903 | 79372983 |
Abnormal dreams | 30.61 | 13.77 | 7 | 360495 | 11405 | 79372481 |
Abdominal pain upper | 30.54 | 13.77 | 1270 | 359232 | 222549 | 79161337 |
Vascular device infection | 30.31 | 13.77 | 5 | 360497 | 10271 | 79373615 |
Pseudomonas infection | 30.08 | 13.77 | 30 | 360472 | 20873 | 79363013 |
Hypersomnia | 30.05 | 13.77 | 36 | 360466 | 23050 | 79360836 |
Bundle branch block right | 29.98 | 13.77 | 7 | 360495 | 11244 | 79372642 |
Personality change | 29.89 | 13.77 | 5 | 360497 | 10165 | 79373721 |
Rash macular | 29.84 | 13.77 | 53 | 360449 | 28846 | 79355040 |
Cerebral ischaemia | 29.76 | 13.77 | 7 | 360495 | 11188 | 79372698 |
COVID-19 pneumonia | 29.70 | 13.77 | 53 | 360449 | 28796 | 79355090 |
Colitis ulcerative | 29.70 | 13.77 | 71 | 360431 | 34671 | 79349215 |
Abortion spontaneous | 29.67 | 13.77 | 55 | 360447 | 29452 | 79354434 |
Glycosylated haemoglobin increased | 29.65 | 13.77 | 26 | 360476 | 19234 | 79364652 |
Enterococcal infection | 29.55 | 13.77 | 17 | 360485 | 15643 | 79368243 |
Benign prostatic hyperplasia | 29.45 | 13.77 | 8 | 360494 | 11604 | 79372282 |
Laryngitis | 29.41 | 13.77 | 147 | 360355 | 15892 | 79367994 |
Escherichia infection | 29.37 | 13.77 | 23 | 360479 | 17994 | 79365892 |
Colitis microscopic | 29.18 | 13.77 | 111 | 360391 | 10657 | 79373229 |
Pulmonary mass | 29.17 | 13.77 | 228 | 360274 | 28806 | 79355080 |
Carpal tunnel syndrome | 29.04 | 13.77 | 169 | 360333 | 19359 | 79364527 |
Thrombotic microangiopathy | 28.96 | 13.77 | 29 | 360473 | 20140 | 79363746 |
Rash pruritic | 28.95 | 13.77 | 470 | 360032 | 71159 | 79312727 |
Retching | 28.85 | 13.77 | 22 | 360480 | 17445 | 79366441 |
Neoplasm malignant | 28.83 | 13.77 | 244 | 360258 | 31566 | 79352320 |
Pulseless electrical activity | 28.74 | 13.77 | 14 | 360488 | 14146 | 79369740 |
Walking aid user | 28.66 | 13.77 | 106 | 360396 | 10042 | 79373844 |
Hepatic cirrhosis | 28.65 | 13.77 | 262 | 360240 | 34644 | 79349242 |
Nephropathy toxic | 28.60 | 13.77 | 30 | 360472 | 20389 | 79363497 |
Hemiplegia | 28.50 | 13.77 | 16 | 360486 | 14923 | 79368963 |
Device leakage | 28.45 | 13.77 | 7 | 360495 | 10849 | 79373037 |
Hypovolaemic shock | 28.36 | 13.77 | 10 | 360492 | 12266 | 79371620 |
Drug level below therapeutic | 28.28 | 13.77 | 5 | 360497 | 9765 | 79374121 |
Muscular weakness | 28.19 | 13.77 | 534 | 359968 | 160195 | 79223691 |
Hyperthermia | 28.19 | 13.77 | 24 | 360478 | 18013 | 79365873 |
Cystitis haemorrhagic | 28.11 | 13.77 | 4 | 360498 | 9168 | 79374718 |
Apnoea | 27.97 | 13.77 | 9 | 360493 | 11695 | 79372191 |
Soft tissue disorder | 27.95 | 13.77 | 54 | 360448 | 3461 | 79380425 |
Skin reaction | 27.88 | 13.77 | 145 | 360357 | 15923 | 79367963 |
Exercise tolerance decreased | 27.70 | 13.77 | 4 | 360498 | 9067 | 79374819 |
Osteomyelitis | 27.65 | 13.77 | 248 | 360254 | 32617 | 79351269 |
Depression | 27.63 | 13.77 | 757 | 359745 | 216033 | 79167853 |
Hepatocellular carcinoma | 27.50 | 13.77 | 4 | 360498 | 9017 | 79374869 |
Nail psoriasis | 27.42 | 13.77 | 23 | 360479 | 622 | 79383264 |
Tender joint count | 27.42 | 13.77 | 15 | 360487 | 194 | 79383692 |
Underdose | 27.36 | 13.77 | 69 | 360433 | 33082 | 79350804 |
Loss of employment | 27.33 | 13.77 | 45 | 360457 | 2542 | 79381344 |
Respiratory tract infection | 27.33 | 13.77 | 120 | 360382 | 48569 | 79335317 |
Premature labour | 27.32 | 13.77 | 3 | 360499 | 8387 | 79375499 |
Hepatomegaly | 27.26 | 13.77 | 27 | 360475 | 18847 | 79365039 |
Osteonecrosis of jaw | 27.11 | 13.77 | 102 | 360400 | 43124 | 79340762 |
Brain natriuretic peptide increased | 27.00 | 13.77 | 4 | 360498 | 8896 | 79374990 |
Acute hepatic failure | 26.98 | 13.77 | 60 | 360442 | 30053 | 79353833 |
Cholangitis | 26.90 | 13.77 | 12 | 360490 | 12764 | 79371122 |
Multiple allergies | 26.86 | 13.77 | 106 | 360396 | 10354 | 79373532 |
Hypertriglyceridaemia | 26.78 | 13.77 | 12 | 360490 | 12728 | 79371158 |
Knee deformity | 26.72 | 13.77 | 31 | 360471 | 1254 | 79382632 |
Mean cell haemoglobin decreased | 26.67 | 13.77 | 75 | 360427 | 6149 | 79377737 |
Renal disorder | 26.64 | 13.77 | 99 | 360403 | 42006 | 79341880 |
Prostatic specific antigen increased | 26.63 | 13.77 | 7 | 360495 | 10379 | 79373507 |
Impaired quality of life | 26.60 | 13.77 | 16 | 360486 | 14370 | 79369516 |
Neurological symptom | 26.53 | 13.77 | 4 | 360498 | 8779 | 79375107 |
Bacterial sepsis | 26.52 | 13.77 | 3 | 360499 | 8195 | 79375691 |
Jaundice cholestatic | 26.40 | 13.77 | 9 | 360493 | 11275 | 79372611 |
Diffuse large B-cell lymphoma | 26.24 | 13.77 | 11 | 360491 | 12138 | 79371748 |
Disease susceptibility | 26.19 | 13.77 | 17 | 360485 | 306 | 79383580 |
Haematocrit decreased | 26.09 | 13.77 | 166 | 360336 | 61146 | 79322740 |
Bedridden | 26.01 | 13.77 | 116 | 360386 | 11963 | 79371923 |
Middle lobe syndrome | 25.92 | 13.77 | 9 | 360493 | 33 | 79383853 |
Myositis | 25.91 | 13.77 | 29 | 360473 | 19139 | 79364747 |
Gout | 25.90 | 13.77 | 45 | 360457 | 24704 | 79359182 |
Bacterial infection | 25.89 | 13.77 | 65 | 360437 | 31215 | 79352671 |
Large intestine perforation | 25.84 | 13.77 | 17 | 360485 | 14550 | 79369336 |
Hepatic fibrosis | 25.77 | 13.77 | 82 | 360420 | 7198 | 79376688 |
Hepatitis | 25.72 | 13.77 | 374 | 360128 | 55353 | 79328533 |
Blood potassium increased | 25.69 | 13.77 | 59 | 360443 | 29216 | 79354670 |
Neuralgia | 25.64 | 13.77 | 72 | 360430 | 33312 | 79350574 |
Abscess | 25.64 | 13.77 | 40 | 360462 | 22911 | 79360975 |
Lipase increased | 25.63 | 13.77 | 22 | 360480 | 16444 | 79367442 |
Localised oedema | 25.50 | 13.77 | 3 | 360499 | 7949 | 79375937 |
Pregnancy | 25.42 | 13.77 | 208 | 360294 | 26643 | 79357243 |
Peritonitis bacterial | 25.40 | 13.77 | 6 | 360496 | 9561 | 79374325 |
Rheumatoid factor | 25.34 | 13.77 | 18 | 360484 | 378 | 79383508 |
Nervous system disorder | 25.32 | 13.77 | 52 | 360450 | 26804 | 79357082 |
Pyelonephritis | 25.28 | 13.77 | 33 | 360469 | 20355 | 79363531 |
Haemolytic anaemia | 25.16 | 13.77 | 26 | 360476 | 17794 | 79366092 |
Extra dose administered | 25.03 | 13.77 | 4 | 360498 | 8411 | 79375475 |
Neck mass | 25.01 | 13.77 | 59 | 360443 | 4345 | 79379541 |
Hyperuricaemia | 24.98 | 13.77 | 11 | 360491 | 11788 | 79372098 |
Hypercapnia | 24.95 | 13.77 | 5 | 360497 | 8930 | 79374956 |
Peripheral sensory neuropathy | 24.80 | 13.77 | 14 | 360488 | 13019 | 79370867 |
Nystagmus | 24.79 | 13.77 | 7 | 360495 | 9897 | 79373989 |
Injection site pain | 24.78 | 13.77 | 425 | 360077 | 129413 | 79254473 |
Azotaemia | 24.47 | 13.77 | 4 | 360498 | 8272 | 79375614 |
Carotid artery stenosis | 24.25 | 13.77 | 5 | 360497 | 8753 | 79375133 |
Steatohepatitis | 24.22 | 13.77 | 26 | 360476 | 964 | 79382922 |
Immobile | 24.19 | 13.77 | 78 | 360424 | 6895 | 79376991 |
Procedural pain | 24.14 | 13.77 | 42 | 360460 | 23042 | 79360844 |
Juvenile idiopathic arthritis | 24.06 | 13.77 | 61 | 360441 | 4702 | 79379184 |
Therapeutic response unexpected | 24.00 | 13.77 | 33 | 360469 | 19913 | 79363973 |
Blood pressure systolic decreased | 23.97 | 13.77 | 10 | 360492 | 11066 | 79372820 |
Hepatitis acute | 23.90 | 13.77 | 21 | 360481 | 15521 | 79368365 |
Throat tightness | 23.88 | 13.77 | 57 | 360445 | 27850 | 79356036 |
Progressive multifocal leukoencephalopathy | 23.88 | 13.77 | 35 | 360467 | 20565 | 79363321 |
Metabolic disorder | 23.86 | 13.77 | 6 | 360496 | 9164 | 79374722 |
Thinking abnormal | 23.83 | 13.77 | 15 | 360487 | 13146 | 79370740 |
Petechiae | 23.78 | 13.77 | 35 | 360467 | 20530 | 79363356 |
Cerebral atrophy | 23.66 | 13.77 | 4 | 360498 | 8071 | 79375815 |
Left ventricular failure | 23.56 | 13.77 | 7 | 360495 | 9574 | 79374312 |
Gastric haemorrhage | 23.55 | 13.77 | 20 | 360482 | 15030 | 79368856 |
Cold sweat | 23.46 | 13.77 | 30 | 360472 | 18669 | 79365217 |
Restless legs syndrome | 23.43 | 13.77 | 34 | 360468 | 20058 | 79363828 |
Chronic sinusitis | 23.38 | 13.77 | 15 | 360487 | 13011 | 79370875 |
Congestive cardiomyopathy | 23.37 | 13.77 | 12 | 360490 | 11768 | 79372118 |
Device malfunction | 23.37 | 13.77 | 38 | 360464 | 21410 | 79362476 |
Rheumatic disorder | 23.28 | 13.77 | 47 | 360455 | 3111 | 79380775 |
Sensory loss | 23.26 | 13.77 | 15 | 360487 | 12976 | 79370910 |
Coronary artery occlusion | 23.19 | 13.77 | 21 | 360481 | 15294 | 79368592 |
Refusal of treatment by patient | 23.17 | 13.77 | 6 | 360496 | 8985 | 79374901 |
Urticarial vasculitis | 23.14 | 13.77 | 20 | 360482 | 564 | 79383322 |
Cerebral haematoma | 23.13 | 13.77 | 4 | 360498 | 7938 | 79375948 |
Food allergy | 23.06 | 13.77 | 10 | 360492 | 10814 | 79373072 |
Eye disorder | 23.05 | 13.77 | 183 | 360319 | 23229 | 79360657 |
Muscle tightness | 23.00 | 13.77 | 15 | 360487 | 12899 | 79370987 |
Hiatus hernia | 22.96 | 13.77 | 44 | 360458 | 23268 | 79360618 |
Blood culture positive | 22.95 | 13.77 | 5 | 360497 | 8424 | 79375462 |
Musculoskeletal discomfort | 22.91 | 13.77 | 161 | 360341 | 19674 | 79364212 |
Pneumonia viral | 22.87 | 13.77 | 92 | 360410 | 9066 | 79374820 |
Product monitoring error | 22.84 | 13.77 | 6 | 360496 | 8900 | 79374986 |
Feeling cold | 22.78 | 13.77 | 61 | 360441 | 28668 | 79355218 |
Erythema | 22.77 | 13.77 | 803 | 359699 | 222487 | 79161399 |
Smear cervix abnormal | 22.71 | 13.77 | 41 | 360461 | 2495 | 79381391 |
Ventricular arrhythmia | 22.59 | 13.77 | 6 | 360496 | 8834 | 79375052 |
Transplant rejection | 22.56 | 13.77 | 33 | 360469 | 19404 | 79364482 |
Hypertonia | 22.53 | 13.77 | 3 | 360499 | 7229 | 79376657 |
Potentiating drug interaction | 22.51 | 13.77 | 6 | 360496 | 8813 | 79375073 |
Overwork | 22.50 | 13.77 | 9 | 360493 | 53 | 79383833 |
Erythema multiforme | 22.48 | 13.77 | 28 | 360474 | 17623 | 79366263 |
Cardiac tamponade | 22.41 | 13.77 | 7 | 360495 | 9269 | 79374617 |
Generalised oedema | 22.28 | 13.77 | 46 | 360456 | 23663 | 79360223 |
Duodenal ulcer haemorrhage | 22.25 | 13.77 | 3 | 360499 | 7160 | 79376726 |
Staphylococcal infection | 22.24 | 13.77 | 163 | 360339 | 58132 | 79325754 |
Glomerular filtration rate decreased | 22.23 | 13.77 | 43 | 360459 | 22659 | 79361227 |
Rhinitis allergic | 22.19 | 13.77 | 14 | 360488 | 12255 | 79371631 |
Sinus node dysfunction | 22.16 | 13.77 | 4 | 360498 | 7697 | 79376189 |
Diabetic eye disease | 22.08 | 13.77 | 12 | 360490 | 153 | 79383733 |
Allergy to chemicals | 21.96 | 13.77 | 41 | 360461 | 2561 | 79381325 |
Pulmonary function test decreased | 21.90 | 13.77 | 4 | 360498 | 7633 | 79376253 |
Caesarean section | 21.73 | 13.77 | 15 | 360487 | 12520 | 79371366 |
Dermatitis acneiform | 21.66 | 13.77 | 9 | 360493 | 9984 | 79373902 |
Eyelid oedema | 21.65 | 13.77 | 18 | 360484 | 13669 | 79370217 |
Mean cell haemoglobin concentration abnormal | 21.62 | 13.77 | 12 | 360490 | 160 | 79383726 |
Immunosuppressant drug level increased | 21.47 | 13.77 | 7 | 360495 | 9020 | 79374866 |
Inflammatory pain | 21.46 | 13.77 | 25 | 360477 | 1016 | 79382870 |
Lupus vulgaris | 21.41 | 13.77 | 47 | 360455 | 3299 | 79380587 |
Haemolysis | 21.34 | 13.77 | 16 | 360486 | 12796 | 79371090 |
Paralysis | 21.26 | 13.77 | 17 | 360485 | 13160 | 79370726 |
Food intolerance | 21.25 | 13.77 | 51 | 360451 | 3797 | 79380089 |
Muscle relaxant therapy | 21.23 | 13.77 | 12 | 360490 | 166 | 79383720 |
Brain herniation | 21.21 | 13.77 | 4 | 360498 | 7459 | 79376427 |
Cardiac failure chronic | 21.13 | 13.77 | 12 | 360490 | 11123 | 79372763 |
Metastasis | 21.09 | 13.77 | 3 | 360499 | 6877 | 79377009 |
Eye pruritus | 20.99 | 13.77 | 38 | 360464 | 20532 | 79363354 |
Product label confusion | 20.97 | 13.77 | 31 | 360471 | 1595 | 79382291 |
Therapy change | 20.96 | 13.77 | 4 | 360498 | 7395 | 79376491 |
Spinal meningioma benign | 20.86 | 13.77 | 10 | 360492 | 96 | 79383790 |
Eyelid ptosis | 20.82 | 13.77 | 12 | 360490 | 11032 | 79372854 |
Inflammatory marker increased | 20.81 | 13.77 | 100 | 360402 | 10640 | 79373246 |
Tenderness | 20.71 | 13.77 | 180 | 360322 | 23462 | 79360424 |
Limb operation | 20.66 | 13.77 | 47 | 360455 | 3379 | 79380507 |
Embolic stroke | 20.60 | 13.77 | 5 | 360497 | 7821 | 79376065 |
Facial paralysis | 20.56 | 13.77 | 40 | 360462 | 21032 | 79362854 |
Aplasia pure red cell | 20.54 | 13.77 | 5 | 360497 | 7805 | 79376081 |
Onychomadesis | 20.38 | 13.77 | 61 | 360441 | 5181 | 79378705 |
Pneumothorax | 20.37 | 13.77 | 63 | 360439 | 28260 | 79355626 |
Blood albumin decreased | 20.36 | 13.77 | 50 | 360452 | 24193 | 79359693 |
Glaucoma | 20.31 | 13.77 | 156 | 360346 | 19605 | 79364281 |
Thrombosis | 20.29 | 13.77 | 263 | 360239 | 83837 | 79300049 |
Hepatic steatosis | 20.16 | 13.77 | 260 | 360242 | 37478 | 79346408 |
Arteriosclerosis | 20.14 | 13.77 | 32 | 360470 | 18195 | 79365691 |
Hepatic ischaemia | 20.08 | 13.77 | 25 | 360477 | 1090 | 79382796 |
Hepatic necrosis | 20.04 | 13.77 | 8 | 360494 | 9092 | 79374794 |
Mood altered | 20.03 | 13.77 | 31 | 360471 | 17816 | 79366070 |
Concomitant disease aggravated | 20.00 | 13.77 | 18 | 360484 | 13149 | 79370737 |
Aortic valve incompetence | 19.99 | 13.77 | 9 | 360493 | 9521 | 79374365 |
Amylase increased | 19.99 | 13.77 | 13 | 360489 | 11196 | 79372690 |
Increased appetite | 19.90 | 13.77 | 15 | 360487 | 11963 | 79371923 |
Breast cancer metastatic | 19.89 | 13.77 | 7 | 360495 | 8595 | 79375291 |
Blood lactic acid increased | 19.87 | 13.77 | 17 | 360485 | 12727 | 79371159 |
Ammonia increased | 19.86 | 13.77 | 5 | 360497 | 7630 | 79376256 |
Decubitus ulcer | 19.85 | 13.77 | 25 | 360477 | 15662 | 79368224 |
Wheelchair user | 19.85 | 13.77 | 67 | 360435 | 6065 | 79377821 |
Tongue oedema | 19.84 | 13.77 | 4 | 360498 | 7113 | 79376773 |
Hepatitis C | 19.72 | 13.77 | 15 | 360487 | 11910 | 79371976 |
Cholecystitis acute | 19.71 | 13.77 | 19 | 360483 | 13432 | 79370454 |
Neck surgery | 19.71 | 13.77 | 32 | 360470 | 1787 | 79382099 |
Viral upper respiratory tract infection | 19.68 | 13.77 | 87 | 360415 | 8939 | 79374947 |
Hip fracture | 19.67 | 13.77 | 72 | 360430 | 30689 | 79353197 |
Alanine aminotransferase increased | 19.63 | 13.77 | 911 | 359591 | 161659 | 79222227 |
Colon cancer | 19.60 | 13.77 | 22 | 360480 | 14501 | 79369385 |
Nervousness | 19.59 | 13.77 | 81 | 360421 | 33334 | 79350552 |
Device occlusion | 19.53 | 13.77 | 15 | 360487 | 11851 | 79372035 |
Rib fracture | 19.51 | 13.77 | 63 | 360439 | 27884 | 79356002 |
Spinal disorder | 19.50 | 13.77 | 95 | 360407 | 10165 | 79373721 |
Renal tubular disorder | 19.48 | 13.77 | 3 | 360499 | 6483 | 79377403 |
Pulmonary alveolar haemorrhage | 19.48 | 13.77 | 14 | 360488 | 11443 | 79372443 |
Lung infiltration | 19.45 | 13.77 | 47 | 360455 | 22865 | 79361021 |
Eye movement disorder | 19.43 | 13.77 | 6 | 360496 | 8005 | 79375881 |
Supraventricular extrasystoles | 19.32 | 13.77 | 4 | 360498 | 6983 | 79376903 |
Hydrocephalus | 19.31 | 13.77 | 8 | 360494 | 8892 | 79374994 |
Heart rate irregular | 19.29 | 13.77 | 79 | 360423 | 32600 | 79351286 |
Squamous cell carcinoma of skin | 19.23 | 13.77 | 21 | 360481 | 14012 | 79369874 |
Pleural thickening | 19.21 | 13.77 | 42 | 360460 | 2940 | 79380946 |
Ventricular hypertrophy | 19.13 | 13.77 | 4 | 360498 | 6934 | 79376952 |
Unevaluable event | 19.07 | 13.77 | 160 | 360342 | 55425 | 79328461 |
Viral infection | 19.06 | 13.77 | 115 | 360387 | 42901 | 79340985 |
Memory impairment | 19.04 | 13.77 | 373 | 360129 | 111361 | 79272525 |
Hyperphosphataemia | 19.04 | 13.77 | 3 | 360499 | 6373 | 79377513 |
Extrasystoles | 19.02 | 13.77 | 5 | 360497 | 7414 | 79376472 |
Hyperventilation | 19.01 | 13.77 | 6 | 360496 | 7893 | 79375993 |
Presbyacusis | 18.91 | 13.77 | 39 | 360463 | 2621 | 79381265 |
Bowel movement irregularity | 18.87 | 13.77 | 3 | 360499 | 6331 | 79377555 |
Hot flush | 18.81 | 13.77 | 158 | 360344 | 54719 | 79329167 |
Gastritis erosive | 18.78 | 13.77 | 13 | 360489 | 10834 | 79373052 |
Lung disorder | 18.73 | 13.77 | 487 | 360015 | 80070 | 79303816 |
Forced expiratory volume decreased | 18.69 | 13.77 | 6 | 360496 | 7808 | 79376078 |
Peripheral coldness | 18.64 | 13.77 | 27 | 360475 | 15943 | 79367943 |
Pleural fibrosis | 18.63 | 13.77 | 51 | 360451 | 4116 | 79379770 |
Post procedural complication | 18.59 | 13.77 | 51 | 360451 | 23778 | 79360108 |
Haemorrhoidal haemorrhage | 18.57 | 13.77 | 4 | 360498 | 6791 | 79377095 |
Ageusia | 18.56 | 13.77 | 29 | 360473 | 16603 | 79367283 |
Retinal haemorrhage | 18.47 | 13.77 | 7 | 360495 | 8210 | 79375676 |
Tender joint count increased | 18.46 | 13.77 | 13 | 360489 | 269 | 79383617 |
Vitreous floaters | 18.40 | 13.77 | 5 | 360497 | 7251 | 79376635 |
Swollen joint count | 18.38 | 13.77 | 25 | 360477 | 1190 | 79382696 |
Sebaceous gland infection | 18.35 | 13.77 | 11 | 360491 | 171 | 79383715 |
No adverse event | 18.34 | 13.77 | 96 | 360406 | 37096 | 79346790 |
Dry throat | 18.28 | 13.77 | 6 | 360496 | 7700 | 79376186 |
Amenorrhoea | 18.23 | 13.77 | 6 | 360496 | 7686 | 79376200 |
Prescribed underdose | 18.23 | 13.77 | 209 | 360293 | 29305 | 79354581 |
Gastric ulcer haemorrhage | 18.21 | 13.77 | 9 | 360493 | 9018 | 79374868 |
Intervertebral disc degeneration | 18.15 | 13.77 | 128 | 360374 | 15657 | 79368229 |
Dermatitis contact | 18.09 | 13.77 | 14 | 360488 | 11019 | 79372867 |
Blood phosphorus decreased | 18.07 | 13.77 | 4 | 360498 | 6664 | 79377222 |
Ocular hyperaemia | 18.05 | 13.77 | 66 | 360436 | 28140 | 79355746 |
Blood triglycerides increased | 17.98 | 13.77 | 43 | 360459 | 20997 | 79362889 |
Nerve block | 17.93 | 13.77 | 19 | 360483 | 694 | 79383192 |
Hyperpyrexia | 17.89 | 13.77 | 3 | 360499 | 6089 | 79377797 |
Rotator cuff syndrome | 17.82 | 13.77 | 117 | 360385 | 13978 | 79369908 |
Oral discomfort | 17.57 | 13.77 | 89 | 360413 | 9671 | 79374215 |
Urine analysis abnormal | 17.49 | 13.77 | 4 | 360498 | 6516 | 79377370 |
Elbow operation | 17.45 | 13.77 | 14 | 360488 | 355 | 79383531 |
Muscle spasms | 17.44 | 13.77 | 630 | 359872 | 174100 | 79209786 |
Large intestine polyp | 17.43 | 13.77 | 19 | 360483 | 12689 | 79371197 |
Left ventricular hypertrophy | 17.36 | 13.77 | 15 | 360487 | 11176 | 79372710 |
Metastases to lymph nodes | 17.30 | 13.77 | 13 | 360489 | 10384 | 79373502 |
Micturition urgency | 17.23 | 13.77 | 19 | 360483 | 12622 | 79371264 |
Multiple sclerosis | 17.16 | 13.77 | 48 | 360454 | 22234 | 79361652 |
Drug level above therapeutic | 17.14 | 13.77 | 9 | 360493 | 8714 | 79375172 |
Feeding disorder | 17.09 | 13.77 | 129 | 360373 | 16125 | 79367761 |
Peripheral arterial occlusive disease | 17.01 | 13.77 | 8 | 360494 | 8250 | 79375636 |
Urosepsis | 16.96 | 13.77 | 62 | 360440 | 26433 | 79357453 |
Spinal cord compression | 16.93 | 13.77 | 4 | 360498 | 6373 | 79377513 |
Pneumonia bacterial | 16.93 | 13.77 | 39 | 360463 | 19292 | 79364594 |
Fibrin D dimer increased | 16.90 | 13.77 | 9 | 360493 | 8645 | 79375241 |
Haemorrhagic stroke | 16.90 | 13.77 | 15 | 360487 | 11031 | 79372855 |
Weber tuning fork test abnormal | 16.89 | 13.77 | 9 | 360493 | 110 | 79383776 |
Graft versus host disease in gastrointestinal tract | 16.85 | 13.77 | 4 | 360498 | 6352 | 79377534 |
Intervertebral disc compression | 16.84 | 13.77 | 25 | 360477 | 1291 | 79382595 |
Pancreatic carcinoma | 16.81 | 13.77 | 22 | 360480 | 13555 | 79370331 |
Haemarthrosis | 16.77 | 13.77 | 3 | 360499 | 5809 | 79378077 |
Oral disorder | 16.76 | 13.77 | 90 | 360412 | 10005 | 79373881 |
Coeliac disease | 16.72 | 13.77 | 98 | 360404 | 11253 | 79372633 |
Pyopneumothorax | 16.67 | 13.77 | 8 | 360494 | 77 | 79383809 |
Influenza like illness | 16.66 | 13.77 | 226 | 360276 | 71481 | 79312405 |
Malignant neoplasm of conjunctiva | 16.61 | 13.77 | 7 | 360495 | 48 | 79383838 |
Incoherent | 16.55 | 13.77 | 7 | 360495 | 7685 | 79376201 |
Gangrene | 16.53 | 13.77 | 10 | 360492 | 8954 | 79374932 |
Rebound effect | 16.50 | 13.77 | 6 | 360496 | 7220 | 79376666 |
Head discomfort | 16.46 | 13.77 | 25 | 360477 | 14477 | 79369409 |
Petit mal epilepsy | 16.43 | 13.77 | 3 | 360499 | 5724 | 79378162 |
Device related sepsis | 16.40 | 13.77 | 4 | 360498 | 6236 | 79377650 |
Hypoaesthesia oral | 16.37 | 13.77 | 24 | 360478 | 14100 | 79369786 |
Infusion site extravasation | 16.36 | 13.77 | 13 | 360489 | 10095 | 79373791 |
Tooth infection | 16.30 | 13.77 | 143 | 360359 | 18689 | 79365197 |
Clear cell renal cell carcinoma | 16.28 | 13.77 | 36 | 360466 | 2540 | 79381346 |
Gastroenteritis | 16.24 | 13.77 | 89 | 360413 | 33993 | 79349893 |
Dermatitis exfoliative | 16.21 | 13.77 | 15 | 360487 | 10814 | 79373072 |
Cartilage atrophy | 16.21 | 13.77 | 10 | 360492 | 164 | 79383722 |
Intestinal perforation | 16.21 | 13.77 | 34 | 360468 | 17392 | 79366494 |
Blood uric acid increased | 16.18 | 13.77 | 22 | 360480 | 13338 | 79370548 |
Adenovirus infection | 16.18 | 13.77 | 9 | 360493 | 8438 | 79375448 |
Pseudomonal sepsis | 16.14 | 13.77 | 4 | 360498 | 6170 | 79377716 |
Abnormal faeces | 16.12 | 13.77 | 7 | 360495 | 7564 | 79376322 |
Arthritis infective | 16.02 | 13.77 | 77 | 360425 | 8194 | 79375692 |
Gastrointestinal perforation | 16.00 | 13.77 | 4 | 360498 | 6133 | 79377753 |
Normal newborn | 15.93 | 13.77 | 6 | 360496 | 7066 | 79376820 |
Systemic inflammatory response syndrome | 15.88 | 13.77 | 17 | 360485 | 11448 | 79372438 |
Endocrine ophthalmopathy | 15.88 | 13.77 | 18 | 360484 | 710 | 79383176 |
Hyperammonaemia | 15.87 | 13.77 | 16 | 360486 | 11077 | 79372809 |
Leukoencephalopathy | 15.85 | 13.77 | 8 | 360494 | 7921 | 79375965 |
Cachexia | 15.84 | 13.77 | 16 | 360486 | 11067 | 79372819 |
Polyneuropathy | 15.80 | 13.77 | 56 | 360446 | 24095 | 79359791 |
Snoring | 15.78 | 13.77 | 3 | 360499 | 5563 | 79378323 |
Nasal congestion | 15.78 | 13.77 | 247 | 360255 | 76305 | 79307581 |
Gastrointestinal necrosis | 15.78 | 13.77 | 3 | 360499 | 5562 | 79378324 |
Injury | 15.63 | 13.77 | 460 | 360042 | 77036 | 79306850 |
Pyelonephritis acute | 15.56 | 13.77 | 4 | 360498 | 6019 | 79377867 |
Ossicle disorder | 15.49 | 13.77 | 6 | 360496 | 32 | 79383854 |
Drug effective for unapproved indication | 15.47 | 13.77 | 4 | 360498 | 5997 | 79377889 |
Anal fistula | 15.46 | 13.77 | 6 | 360496 | 6938 | 79376948 |
Vaginal haematoma | 15.41 | 13.77 | 9 | 360493 | 133 | 79383753 |
Respiration abnormal | 15.35 | 13.77 | 8 | 360494 | 7780 | 79376106 |
Sexual dysfunction | 15.27 | 13.77 | 8 | 360494 | 7755 | 79376131 |
Major depression | 15.23 | 13.77 | 11 | 360491 | 8969 | 79374917 |
Skin irritation | 15.20 | 13.77 | 17 | 360485 | 11223 | 79372663 |
Nail operation | 15.19 | 13.77 | 17 | 360485 | 661 | 79383225 |
Drug specific antibody present | 15.18 | 13.77 | 65 | 360437 | 6587 | 79377299 |
Cataract | 15.17 | 13.77 | 378 | 360124 | 61742 | 79322144 |
Elbow deformity | 15.14 | 13.77 | 26 | 360476 | 1521 | 79382365 |
Thrombotic thrombocytopenic purpura | 15.07 | 13.77 | 5 | 360497 | 6371 | 79377515 |
Splenomegaly | 15.04 | 13.77 | 46 | 360456 | 20708 | 79363178 |
Pseudomembranous colitis | 15.02 | 13.77 | 3 | 360499 | 5371 | 79378515 |
Ureaplasma infection | 14.98 | 13.77 | 21 | 360481 | 1029 | 79382857 |
Back injury | 14.96 | 13.77 | 90 | 360412 | 10433 | 79373453 |
Stress at work | 14.92 | 13.77 | 22 | 360480 | 1129 | 79382757 |
Staphylococcal bacteraemia | 14.92 | 13.77 | 20 | 360482 | 12198 | 79371688 |
Myasthenia gravis | 14.88 | 13.77 | 15 | 360487 | 10384 | 79373502 |
Functional gastrointestinal disorder | 14.83 | 13.77 | 53 | 360449 | 4937 | 79378949 |
Gestational diabetes | 14.76 | 13.77 | 5 | 360497 | 6288 | 79377598 |
Haemophagocytic lymphohistiocytosis | 14.71 | 13.77 | 50 | 360452 | 21787 | 79362099 |
CD4/CD8 ratio increased | 14.69 | 13.77 | 5 | 360497 | 17 | 79383869 |
Systemic candida | 14.60 | 13.77 | 6 | 360496 | 6700 | 79377186 |
Drug dose omission by device | 14.60 | 13.77 | 5 | 360497 | 6245 | 79377641 |
Mycobacterium marinum infection | 14.55 | 13.77 | 14 | 360488 | 455 | 79383431 |
Anaphylactic shock | 14.53 | 13.77 | 99 | 360403 | 35897 | 79347989 |
Respiratory rate decreased | 14.50 | 13.77 | 3 | 360499 | 5240 | 79378646 |
Neutrophilia | 14.48 | 13.77 | 9 | 360493 | 7942 | 79375944 |
Optic neuritis | 14.48 | 13.77 | 13 | 360489 | 9507 | 79374379 |
Portal hypertension | 14.47 | 13.77 | 7 | 360495 | 7101 | 79376785 |
Sudden cardiac death | 14.43 | 13.77 | 3 | 360499 | 5222 | 79378664 |
Splenic embolism | 14.41 | 13.77 | 10 | 360492 | 202 | 79383684 |
Kidney transplant rejection | 14.41 | 13.77 | 15 | 360487 | 10231 | 79373655 |
Cardiac granuloma | 14.39 | 13.77 | 4 | 360498 | 5 | 79383881 |
Cytomegalovirus infection reactivation | 14.37 | 13.77 | 11 | 360491 | 8705 | 79375181 |
Flank pain | 14.37 | 13.77 | 44 | 360458 | 19800 | 79364086 |
Pharyngeal oedema | 14.31 | 13.77 | 124 | 360378 | 16148 | 79367738 |
Laryngeal disorder | 14.28 | 13.77 | 21 | 360481 | 1075 | 79382811 |
Expired product administered | 14.27 | 13.77 | 7 | 360495 | 7044 | 79376842 |
Cytopenia | 14.19 | 13.77 | 46 | 360456 | 20337 | 79363549 |
Dry eye | 14.06 | 13.77 | 240 | 360262 | 36691 | 79347195 |
Gingival pain | 14.03 | 13.77 | 12 | 360490 | 8986 | 79374900 |
Cell-mediated cytotoxicity | 13.90 | 13.77 | 6 | 360496 | 44 | 79383842 |
Blood thyroid stimulating hormone increased | 13.89 | 13.77 | 14 | 360488 | 9694 | 79374192 |
Liver abscess | 13.87 | 13.77 | 5 | 360497 | 6049 | 79377837 |
Compartment syndrome | 13.87 | 13.77 | 3 | 360499 | 5079 | 79378807 |
Pulmonary cavitation | 13.86 | 13.77 | 26 | 360476 | 1630 | 79382256 |
Methaemoglobinaemia | 13.77 | 13.77 | 4 | 360498 | 5553 | 79378333 |
None
Source | Code | Description |
---|---|---|
ATC | L04AA13 | ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS IMMUNOSUPPRESSANTS IMMUNOSUPPRESSANTS Selective immunosuppressants |
MeSH PA | D000700 | Analgesics |
MeSH PA | D018712 | Analgesics, Non-Narcotic |
MeSH PA | D000893 | Anti-Inflammatory Agents |
MeSH PA | D000894 | Anti-Inflammatory Agents, Non-Steroidal |
MeSH PA | D018501 | Antirheumatic Agents |
MeSH PA | D007155 | Immunologic Factors |
MeSH PA | D007166 | Immunosuppressive Agents |
MeSH PA | D018373 | Peripheral Nervous System Agents |
MeSH PA | D018689 | Sensory System Agents |
MeSH PA | D004791 | Enzyme Inhibitors |
CHEBI has role | CHEBI:35442 | antiparasitic drugs |
CHEBI has role | CHEBI:35475 | non-steroidal anti-inflammatory agent |
CHEBI has role | CHEBI:35610 | antineoplastic agents |
CHEBI has role | CHEBI:35705 | immunosuppressive agents |
CHEBI has role | CHEBI:37153 | protein serine/threonine phosphatase inhibitors |
CHEBI has role | CHEBI:38637 | tyrosine kinase inhibitors |
CHEBI has role | CHEBI:50266 | Prodrugs |
CHEBI has role | CHEBI:50908 | agente hepatotoxico |
CHEBI has role | CHEBI:68542 | DHODH inhibitor |
CHEBI has role | CHEBI:68543 | pyrimidine synthesis inhibitors |
FDA EPC | N0000175713 | Antirheumatic Agent |
FDA MoA | N0000185501 | Dihydroorotate Dehydrogenase Inhibitors |
FDA EPC | N0000185502 | Pyrimidine Synthesis Inhibitor |
CHEBI has role | CHEBI:49103 | drug metabolites |
Disease | Relation | SNOMED_ID | DOID |
---|---|---|---|
Psoriasis with arthropathy | indication | 33339001 | |
Rheumatoid arthritis | indication | 69896004 | DOID:7148 |
Inactive tuberculosis | contraindication | 11999007 | |
Agranulocytosis | contraindication | 17182001 | DOID:12987 |
Acute tuberculosis | contraindication | 25629007 | |
Immunosuppression | contraindication | 38013005 | |
Hepatic failure | contraindication | 59927004 | |
Chronic type B viral hepatitis | contraindication | 61977001 | |
Acute infectious disease | contraindication | 63171007 | |
Interstitial pneumonia | contraindication | 64667001 | |
Aspergillosis | contraindication | 65553006 | DOID:13564 |
Viral hepatitis type B | contraindication | 66071002 | DOID:2043 |
Kidney disease | contraindication | 90708001 | DOID:557 |
Pancytopenia | contraindication | 127034005 | DOID:12450 |
Chronic hepatitis C | contraindication | 128302006 | |
Liver function tests abnormal | contraindication | 166603001 | |
Disease of liver | contraindication | 235856003 | DOID:409 |
Acute hepatitis C | contraindication | 235866006 | |
Anemia | contraindication | 271737000 | DOID:2355 |
Pregnancy, function | contraindication | 289908002 | |
Thrombocytopenic disorder | contraindication | 302215000 | DOID:1588 |
Peripheral nerve disease | contraindication | 302226006 | |
Neutropenic disorder | contraindication | 303011007 | DOID:1227 |
Breastfeeding (mother) | contraindication | 413712001 | |
Pneumocystosis jiroveci pneumonia | contraindication | 415125002 | DOID:11339 |
Severe Bone Marrow Depression | contraindication |
None
None
Dissociation level | Dissociation constant | Type (acidic/basic) |
---|---|---|
pKa1 | 12.31 | acidic |
None
None
Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
---|---|---|---|---|---|---|---|---|---|
Dihydroorotate dehydrogenase (quinone), mitochondrial | Enzyme | INHIBITOR | IC50 | 5 | CHEMBL | CHEMBL | |||
Sodium-dependent noradrenaline transporter | Transporter | Ki | 5.34 | DRUG MATRIX | |||||
Sodium-dependent dopamine transporter | Transporter | Ki | 5.64 | DRUG MATRIX | |||||
Cytochrome P450 1A2 | Enzyme | IC50 | 6.30 | DRUG MATRIX | |||||
Amine oxidase [flavin-containing] A | Enzyme | IC50 | 4.68 | DRUG MATRIX | |||||
Sodium/nucleoside cotransporter 1 | Transporter | Ki | 5.29 | DRUG MATRIX | |||||
Dihydroorotate dehydrogenase (quinone), mitochondrial | Enzyme | IC50 | 8.05 | CHEMBL | |||||
Dihydroorotate dehydrogenase (quinone), mitochondrial | Enzyme | IC50 | 7.52 | CHEMBL |
ID | Source |
---|---|
4021132 | VUID |
N0000148586 | NUI |
D00749 | KEGG_DRUG |
4021132 | VANDF |
4031717 | VANDF |
C0063041 | UMLSCUI |
CHEBI:6402 | CHEBI |
CHEBI:68540 | CHEBI |
CHEMBL960 | ChEMBL_ID |
DB01097 | DRUGBANK_ID |
D000077339 | MESH_DESCRIPTOR_UI |
3899 | PUBCHEM_CID |
6825 | IUPHAR_LIGAND_ID |
C527525 | MESH_SUPPLEMENTAL_RECORD_UI |
5079 | INN_ID |
G162GK9U4W | UNII |
1310520 | RXNORM |
11870 | MMSL |
28846 | MMSL |
365635 | MMSL |
63949 | MMSL |
7491 | MMSL |
d04349 | MMSL |
d07905 | MMSL |
007642 | NDDF |
014643 | NDDF |
109143003 | SNOMEDCT_US |
386981009 | SNOMEDCT_US |
703785006 | SNOMEDCT_US |
703786007 | SNOMEDCT_US |
C1718383 | UMLSCUI |
DB08880 | DRUGBANK_ID |
7761 | INN_ID |
54684141 | PUBCHEM_CID |
Product | Category | Ingredients | NDC | Form | Quantity | Route | Marketing | Label |
---|---|---|---|---|---|---|---|---|
Arava | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0088-2160 | TABLET, FILM COATED | 10 mg | ORAL | NDA | 27 sections |
Arava | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0088-2160 | TABLET, FILM COATED | 10 mg | ORAL | NDA | 27 sections |
Arava | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0088-2161 | TABLET, FILM COATED | 20 mg | ORAL | NDA | 27 sections |
Arava | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0088-2161 | TABLET, FILM COATED | 20 mg | ORAL | NDA | 27 sections |
Arava | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0088-2162 | TABLET, FILM COATED | 100 mg | ORAL | NDA | 27 sections |
Arava | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0088-2162 | TABLET, FILM COATED | 100 mg | ORAL | NDA | 27 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0955-1735 | TABLET, FILM COATED | 10 mg | ORAL | NDA AUTHORIZED GENERIC | 27 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0955-1735 | TABLET, FILM COATED | 10 mg | ORAL | NDA AUTHORIZED GENERIC | 27 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0955-1737 | TABLET, FILM COATED | 20 mg | ORAL | NDA AUTHORIZED GENERIC | 27 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 0955-1737 | TABLET, FILM COATED | 20 mg | ORAL | NDA AUTHORIZED GENERIC | 27 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10702-277 | TABLET | 10 mg | ORAL | ANDA | 18 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 10702-278 | TABLET | 20 mg | Oral | ANDA | 18 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 23155-043 | TABLET | 10 mg | ORAL | ANDA | 23 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 23155-043 | TABLET | 10 mg | ORAL | ANDA | 23 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 23155-044 | TABLET | 20 mg | ORAL | ANDA | 23 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 23155-044 | TABLET | 20 mg | ORAL | ANDA | 23 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 35573-447 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 27 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 35573-448 | TABLET, FILM COATED | 20 mg | ORAL | ANDA | 27 sections |
LEFLUNOMIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42291-420 | TABLET | 10 mg | ORAL | ANDA | 18 sections |
LEFLUNOMIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 42291-421 | TABLET | 20 mg | ORAL | ANDA | 18 sections |
Leflunomide | Human Prescription Drug Label | 1 | 46708-436 | TABLET | 10 mg | ORAL | ANDA | 26 sections |
Leflunomide | Human Prescription Drug Label | 1 | 46708-436 | TABLET | 10 mg | ORAL | ANDA | 26 sections |
Leflunomide | Human Prescription Drug Label | 1 | 46708-437 | TABLET | 20 mg | ORAL | ANDA | 26 sections |
Leflunomide | Human Prescription Drug Label | 1 | 46708-437 | TABLET | 20 mg | ORAL | ANDA | 26 sections |
Leflunomide | Human Prescription Drug Label | 1 | 50090-5992 | TABLET, FILM COATED | 20 mg | ORAL | ANDA | 26 sections |
LEFLUNOMIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50268-477 | TABLET | 10 mg | ORAL | ANDA | 18 sections |
LEFLUNOMIDE | HUMAN PRESCRIPTION DRUG LABEL | 1 | 50268-478 | TABLET | 20 mg | ORAL | ANDA | 18 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 54868-2319 | TABLET, FILM COATED | 20 mg | ORAL | ANDA | 26 sections |
Leflunomide | HUMAN PRESCRIPTION DRUG LABEL | 1 | 54868-6170 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 26 sections |
Leflunomide | Human Prescription Drug Label | 1 | 59651-348 | TABLET, FILM COATED | 10 mg | ORAL | ANDA | 26 sections |