itopride 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| sulpiride derivatives | 1512 | 122898-67-3 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 0.15 | g | O |
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Trimethylaminuria | 138.56 | 54.93 | 17 | 712 | 124 | 56291214 |
| Pseudomembranous colitis | 87.18 | 54.93 | 17 | 712 | 2886 | 56288452 |
| Peritonitis | 80.90 | 54.93 | 22 | 707 | 16180 | 56275158 |
| Megacolon | 76.12 | 54.93 | 14 | 715 | 1737 | 56289601 |
| Dysbiosis | 66.35 | 54.93 | 11 | 718 | 746 | 56290592 |
| Intestinal perforation | 64.70 | 54.93 | 17 | 712 | 10942 | 56280396 |
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
| MedDRA adverse event term | Likelihood ratio | Likelihood ratio threshold | Patients taking drug having adverse event | Patients taking drug not having adverse event | Patients not taking drug having adverse event | Patients not taking drug not having adverse event |
|---|---|---|---|---|---|---|
| Trimethylaminuria | 143.17 | 35.41 | 18 | 997 | 146 | 70927283 |
| Pseudomembranous colitis | 81.34 | 35.41 | 18 | 997 | 5093 | 70922336 |
| Peritonitis | 72.34 | 35.41 | 23 | 992 | 26136 | 70901293 |
| Megacolon | 72.24 | 35.41 | 15 | 1000 | 3141 | 70924288 |
| Dysbiosis | 69.56 | 35.41 | 12 | 1003 | 932 | 70926497 |
| Intestinal perforation | 60.90 | 35.41 | 18 | 997 | 16026 | 70911403 |
| Clostridium difficile infection | 38.44 | 35.41 | 16 | 999 | 38800 | 70888629 |
| Inhibitory drug interaction | 37.06 | 35.41 | 9 | 1006 | 3798 | 70923631 |
| Drug interaction | 35.93 | 35.41 | 35 | 980 | 381406 | 70546023 |
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | A03FA07 | ALIMENTARY TRACT AND METABOLISM DRUGS FOR FUNCTIONAL GASTROINTESTINAL DISORDERS PROPULSIVES Propulsives |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Chronic gastritis | indication | 8493009 |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 8.61 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D02729 | KEGG_DRUG |
| 122892-31-3 | SECONDARY_CAS_RN |
| C0531483 | UMLSCUI |
| CHEBI:94809 | CHEBI |
| CHEMBL2107457 | ChEMBL_ID |
| DB04924 | DRUGBANK_ID |
| C102254 | MESH_SUPPLEMENTAL_RECORD_UI |
| 3792 | PUBCHEM_CID |
| 6879 | INN_ID |
| 81BMQ80QRL | UNII |
| 017624 | NDDF |
| 017625 | NDDF |
| 1217454005 | SNOMEDCT_US |
| 20691000122100 | SNOMEDCT_US |
Pharmaceutical products:
None