ipriflavone 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
1477 35212-22-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • 7-isopropoxyisoflavone
  • ipriflavone
  • iprivone
  • iprosten
  • osteofix
  • osten
  • Molecular weight: 280.32
  • Formula: C18H16O3
  • CLOGP: 3.92
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 0
  • TPSA: 35.53
  • ALOGS: -4.80
  • ROTB: 3

Drug dosage:

None

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC M05BX01 MUSCULO-SKELETAL SYSTEM
DRUGS FOR TREATMENT OF BONE DISEASES
DRUGS AFFECTING BONE STRUCTURE AND MINERALIZATION
Other drugs affecting bone structure and mineralization
CHEBI has role CHEBI:50646 antiosteoporotic

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Postmenopausal osteoporosis indication 102447009




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

None

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])
Mechanism
action
Bioact sourceMoA source
Prostaglandin G/H synthase 1 Enzyme IC50 5.53 DRUG MATRIX
Sodium-dependent noradrenaline transporter Transporter Ki 5.60 DRUG MATRIX

External reference:

IDSource
4032065 VUID
N0000186568 NUI
D01338 KEGG_DRUG
4032065 VANDF
C0123903 UMLSCUI
CHEBI:31719 CHEBI
CHEMBL165790 ChEMBL_ID
DB13618 DRUGBANK_ID
C018986 MESH_SUPPLEMENTAL_RECORD_UI
3747 PUBCHEM_CID
3521 INN_ID
80BJ7WN25Z UNII
51487 RXNORM
004192 NDDF

Pharmaceutical products:

None