iopanoic acid 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| iodine-containing contrast media | 1465 | 96-83-3 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
Radiopaque medium used as diagnostic aid.
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| BDDCS (Biopharmaceutical Drug Disposition Classification System) | 4 | Benet LZ, Broccatelli F, Oprea TI |
| S (Water solubility) | 0.02 mg/mL | Benet LZ, Broccatelli F, Oprea TI |
| EoM (Fraction excreted unchanged in urine) | 33 % | Benet LZ, Broccatelli F, Oprea TI |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| July 16, 1951 | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | V08AC06 | VARIOUS CONTRAST MEDIA X-RAY CONTRAST MEDIA, IODINATED Watersoluble, hepatotropic X-ray contrast media |
| MeSH PA | D003287 | Contrast Media |
| MeSH PA | D064907 | Diagnostic Uses of Chemicals |
Drug Use | Suggest Off label Use Form| |View source of the data|
| Disease | Relation | SNOMED_ID | DOID |
|---|---|---|---|
| Diagnostic aid | indication | 2949005 | |
| Acute nephropathy | contraindication | 58574008 | |
| Hepatic failure | contraindication | 59927004 | |
| Kidney disease | contraindication | 90708001 | DOID:557 |
| Hb SS disease | contraindication | 127040003 | DOID:10923 |
| Asthma | contraindication | 195967001 | DOID:2841 |
| Pregnancy, function | contraindication | 289908002 | |
| Pheochromocytoma | contraindication | 302835009 | |
| Hypertensive Emergencies | contraindication |
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 4.84 | acidic |
| pKa2 | 2.32 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| 4018259 | VUID |
| N0000146589 | NUI |
| D01014 | KEGG_DRUG |
| 4018259 | VANDF |
| C0022028 | UMLSCUI |
| CHEBI:5951 | CHEBI |
| CHEMBL867 | ChEMBL_ID |
| D007480 | MESH_DESCRIPTOR_UI |
| DB08946 | DRUGBANK_ID |
| 3 | INN_ID |
| FE9794P71J | UNII |
| 3735 | PUBCHEM_CID |
| 5967 | RXNORM |
| 4906 | MMSL |
| d01438 | MMSL |
| 001220 | NDDF |
| 412227008 | SNOMEDCT_US |
| 76155001 | SNOMEDCT_US |
Pharmaceutical products:
None