iocetamic acid Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
iodine-containing contrast media 1451 16034-77-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • iocetamic acid
  • cholebrine
was MH 1975-92 (see under IODOBENZENES 1975-90); use IODOBENZENES to search IOCETAMIC ACID 1975-92
  • Molecular weight: 613.96
  • Formula: C12H13I3N2O3
  • CLOGP: 2.82
  • LIPINSKI: 1
  • HAC: 5
  • HDO: 2
  • TPSA: 83.63
  • ALOGS: -4.06
  • ROTB: 4

  • Status: OFM

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA MALLINCKRODT

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
ATC V08AC07 VARIOUS
CONTRAST MEDIA
X-RAY CONTRAST MEDIA, IODINATED
Watersoluble, hepatotropic X-ray contrast media

Drug Use (View source of the data)

DiseaseRelationSNOMED_IDDOID
Acute nephropathy contraindication 58574008
Hepatic failure contraindication 59927004
Kidney disease contraindication 90708001 DOID:557
Hb SS disease contraindication 127040003 DOID:10923
Asthma contraindication 195967001 DOID:2841
Pregnancy, function contraindication 289908002
Pheochromocytoma contraindication 302835009
Hypertensive Emergencies contraindication

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 4.3 acidic
pKa2 2.02 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4018168 VUID
N0000146505 NUI
D04563 KEGG_DRUG
4018168 VANDF
C0650158 UMLSCUI
CHEBI:91662 CHEBI
CHEMBL1200770 ChEMBL_ID
DB09403 DRUGBANK_ID
C073259 MESH_SUPPLEMENTAL_RECORD_UI
27648 PUBCHEM_CID
2347 INN_ID
FA675Q0E3E UNII
183830 RXNORM
7482 MMSL
d04325 MMSL
001232 NDDF

Pharmaceutical products:

None