adipiodone Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
radiopharmaceuticals, iodine-contained 1455 606-17-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • iodipamide
  • adipiodone
  • iodipamic acid
  • adipiodon
  • meglumine adipiodone
  • iodipamide meglumine
  • iodipamide sodium
  • cholografin meglumine
  • cholografin sodium
A water-soluble radiographic contrast media for cholecystography and intravenous cholangiography.
  • Molecular weight: 1139.77
  • Formula: C20H14I6N2O6
  • CLOGP: 4.19
  • LIPINSKI: 1
  • HAC: 8
  • HDO: 4
  • TPSA: 132.80
  • ALOGS: -5.57
  • ROTB: 9

  • Status: OFM

  • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
April 27, 1954 FDA BRACCO

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

Pharmacologic Action:

SourceCodeDescription
ATC V08AC04 VARIOUS
CONTRAST MEDIA
X-RAY CONTRAST MEDIA, IODINATED
Watersoluble, hepatotropic X-ray contrast media
FDA EPC N0000180185 Radiographic Contrast Agent
FDA MoA N0000010258 X-Ray Contrast Activity
MeSH PA D003287 Contrast Media
MeSH PA D064907 Diagnostic Uses of Chemicals
CHEBI has role CHEBI:37338 radioopaque medium

Drug Use (View source of the data)

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 3.03 acidic
pKa2 3.64 acidic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D007458 MESH_DESCRIPTOR_UI
N0000007781 NUI
C0021971 UMLSCUI
D01774 KEGG_DRUG
3J6WZA9PXS UNII
2618-26-0 SECONDARY_CAS_RN
73212002 SNOMEDCT_US
5936 RXNORM
398939009 SNOMEDCT_US
d01454 MMSL
CHEMBL1165268 ChEMBL_ID
CHEMBL1200350 ChEMBL_ID
CHEMBL1200504 ChEMBL_ID
313 INN_ID
DB04711 DRUGBANK_ID
CHEBI:31176 CHEBI
CHEMBL3989806 ChEMBL_ID
3739 PUBCHEM_CID
7400 IUPHAR_LIGAND_ID
C006753 MESH_SUPPLEMENTAL_RECORD_UI

Pharmaceutical products:

None