indecainide 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
Class I antiarrhythmics, procainamide and lidocaine derivatives 1434 74517-78-5

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • indecainide hydrochloride
  • decabid
  • indecainide
  • ricainide
  • indecainide HCl
  • Molecular weight: 308.43
  • Formula: C20H24N2O
  • CLOGP: 2.46
  • LIPINSKI: 0
  • HAC: 3
  • HDO: 2
  • TPSA: 55.12
  • ALOGS: -5.54
  • ROTB: 6
  • Status: OFM
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
None FDA LILLY

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 10.68 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Sodium channel protein type 5 subunit alpha Ion channel BLOCKER DRUGBANK CHEMBL

External reference:

IDSource
D04521 KEGG_DRUG
73681-12-6 SECONDARY_CAS_RN
C0063455 UMLSCUI
CHEBI:135314 CHEBI
CHEMBL1201242 ChEMBL_ID
CHEMBL1200341 ChEMBL_ID
DB00192 DRUGBANK_ID
C042398 MESH_SUPPLEMENTAL_RECORD_UI
52195 PUBCHEM_CID
5116 INN_ID
3AZF20DM1T UNII
005156 NDDF
005157 NDDF
412207007 SNOMEDCT_US
412208002 SNOMEDCT_US

Pharmaceutical products:

None