Molfile
Inchi
Smiles
Synonyms:
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hydroxyzine pamoate
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hydroxizine
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hydroxyzin
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hydroxyzyne
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tranquizine
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hydroxyzine
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hydroxyzine hydrochloride
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hydroxyzine dihydrochloride
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hydroxyzine HCl
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A histamine H1 receptor antagonist that is effective in the treatment of chronic urticaria, dermatitis, and histamine-mediated pruritus. Unlike its major metabolite CETIRIZINE, it does cause drowsiness. It is also effective as an antiemetic, for relief of anxiety and tension, and as a sedative.
- Molecular weight: 374.91
- Formula: C21H27ClN2O2
- CLOGP: 4
- LIPINSKI: 0
- HAC: 4
- HDO: 1
- TPSA: 35.94
- ALOGS: -3.61
- ROTB: 8
- Status: OFP
Legend: OFP - off patent OFM - off market ONP - on patent
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