hydroxystilbamidine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
1398 495-99-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • hydroxystilbamidine isethionate
  • hydroxystilbamidine
  • hydroxystilbamidine isetionate
  • hydroxystilbamidine hydrochloride
minor descriptor (63-86); on-line & INDEX MEDICUS search STILBAMIDINES (66-86); RN given refers to parent cpd
  • Molecular weight: 280.33
  • Formula: C16H16N4O
  • CLOGP: 1.14
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 5
  • TPSA: 119.97
  • ALOGS: -3.64
  • ROTB: 4
  • Status: OFM
    • Legend:
    OFP - off patent
    OFM - off market
    ONP - on patent

Drug dosage:

None

ADMET properties:

None

Approvals:

DateAgencyCompanyOrphan
Dec. 22, 1953 FDA SANOFI AVENTIS US

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

None

Drug Use | Suggest Off label Use Form| |View source of the data|

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 8.27 acidic
pKa2 9.77 Basic
pKa3 9.17 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

TargetClassPharosUniProtActionTypeActivity value
(-log[M])		Mechanism
action		Bioact sourceMoA source
Trypsin Enzyme AC50 5.50 CHEMBL

External reference:

IDSource
39J262E49W UNII
533-22-2 SECONDARY_CAS_RN
C0063195 UMLSCUI
CHEBI:135161 CHEBI
CHEMBL1301 ChEMBL_ID
5284571 PUBCHEM_CID
DB14753 DRUGBANK_ID
CHEMBL1200847 ChEMBL_ID
CHEMBL2023895 ChEMBL_ID
456 INN_ID
C100274 MESH_SUPPLEMENTAL_RECORD_UI
002967 NDDF
004967 NDDF
43698001 SNOMEDCT_US

Pharmaceutical products:

None