hydrocortisone aceponate 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| corticosteroids, except prednisolone derivatives | 1389 | 74050-20-7 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
| Property | Value | Reference |
|---|---|---|
| S (Water solubility) | 0.23 mg/mL | Bocci G, Oprea TI, Benet LZ |
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | D07AC16 | DERMATOLOGICALS CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS CORTICOSTEROIDS, PLAIN Corticosteroids, potent (group III) |
| FDA MoA | N0000175450 | Corticosteroid Hormone Receptor Agonists |
| FDA EPC | N0000175576 | Corticosteroid |
| MeSH PA | D000893 | Anti-Inflammatory Agents |
| CHEBI has role | CHEBI:35472 | anti-inflammatory drugs |
| CHEBI has role | CHEBI:49167 | anti-asthmatic drugs |
| CHEBI has role | CHEBI:50857 | anti-allergic drugs |
| CHEBI has role | CHEBI:75771 | Mus musculus metabolites |
| CHEBI has role | CHEBI:77746 | Homo sapiens metabolite |
| CHEBI has role | CHEBI:88188 | allergenic drug |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
| Species | Use | Relation |
|---|---|---|
| Cats | Acute otitis externa | Indication |
| Cats | Chronic otitis externa | Indication |
| Cats | Ear canker | Indication |
| Cats | Inflammatory conditions of the external ear canal | Indication |
| Cats | Allergy | Indication |
| Cats | Infectious skin conditions | Indication |
| Cats | Traumatic skin conditions | Indication |
| Cats | Prevention of bacterial infections in superficial wounds | Indication |
| Cats | Prevention of bacterial infections in cuts | Indication |
| Cats | Prevention of bacterial infections in abrasions | Indication |
| Cats | Allergic dermatoses | Indication |
| Cats | Infections associated with minor burns and wounds | Indication |
| Cats | Nonspecific pruritus | Indication |
| Dogs | Acute otitis externa | Indication |
| Dogs | Chronic otitis externa | Indication |
| Dogs | Ear canker | Indication |
| Dogs | Inflammatory conditions of the external ear canal | Indication |
| Dogs | Allergy | Indication |
| Dogs | Infectious skin conditions | Indication |
| Dogs | Traumatic skin conditions | Indication |
| Dogs | Prevention of bacterial infections in superficial wounds | Indication |
| Dogs | Prevention of bacterial infections in cuts | Indication |
| Dogs | Prevention of bacterial infections in abrasions | Indication |
| Dogs | Allergic dermatoses | Indication |
| Dogs | Infections associated with minor burns and wounds | Indication |
| Dogs | Nonspecific pruritus | Indication |
| Horses | No Use Class Stated Or Implied | Indication |
🐶 Veterinary products
| Product | Applicant | Ingredients |
|---|---|---|
| Easotic | Virbac AH Inc. | 3 |
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D06876 | KEGG_DRUG |
| 4017941 | VANDF |
| C0082944 | UMLSCUI |
| CHEBI:17650 | CHEBI |
| CHEMBL2106309 | ChEMBL_ID |
| DB14538 | DRUGBANK_ID |
| C063919 | MESH_SUPPLEMENTAL_RECORD_UI |
| 5847 | INN_ID |
| 2340UP1L2G | UNII |
| 68921 | PUBCHEM_CID |
| DB00741 | DRUGBANK_ID |
| 41277 | RXNORM |
| 2500 | MMSL |
| 4837 | MMSL |
| d00254 | MMSL |
| 002147 | NDDF |
| 005250 | NDDF |
| 16602005 | SNOMEDCT_US |
| 396458002 | SNOMEDCT_US |
| 708195009 | SNOMEDCT_US |
| C0020268 | UMLSCUI |
| 38 | INN_ID |
| 5754 | PUBCHEM_CID |
| D006854 | MESH_DESCRIPTOR_UI |
Pharmaceutical products:
None