hexafluronium 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| quaternary ammonium compounds | 1365 | 317-52-2 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
curarimimetic agent for use with succinylcholine; muscle relaxant; structure; RN given refers to parent cpd
Legend: OFP - off patent OFM - off market ONP - on patent |
Drug dosage:
None
ADMET properties:
None
Approvals:
| Date | Agency | Company | Orphan |
|---|---|---|---|
| None | FDA | MEDPOINTE PHARM HLC |
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | M03AC05 | MUSCULO-SKELETAL SYSTEM MUSCLE RELAXANTS MUSCLE RELAXANTS, PERIPHERALLY ACTING AGENTS Other quaternary ammonium compounds |
| MeSH PA | D018678 | Cholinergic Agents |
| MeSH PA | D018680 | Cholinergic Antagonists |
| MeSH PA | D018377 | Neurotransmitter Agents |
| MeSH PA | D018733 | Nicotinic Antagonists |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
| Target | Class | Pharos | UniProt | Action | Type | Activity value (-log[M]) | Mechanism action | Bioact source | MoA source |
|---|---|---|---|---|---|---|---|---|---|
| Acetylcholinesterase | Enzyme | INHIBITOR | CHEMBL | CHEMBL | |||||
| Acetylcholinesterase | Enzyme | Ki | 5.89 | CHEMBL | |||||
| Butyrylcholinesterase | Enzyme | Ki | 6.47 | CHEMBL |
External reference:
| ID | Source |
|---|---|
| 4018444 | VUID |
| N0000146768 | NUI |
| D04435 | KEGG_DRUG |
| 4018444 | VANDF |
| 4019775 | VANDF |
| CHEBI:135804 | CHEBI |
| CHEMBL1201349 | ChEMBL_ID |
| CHEMBL1200933 | ChEMBL_ID |
| C005034 | MESH_SUPPLEMENTAL_RECORD_UI |
| DB00941 | DRUGBANK_ID |
| 26826 | RXNORM |
| 001713 | NDDF |
| 004690 | NDDF |
| 19978007 | SNOMEDCT_US |
| C0062619 | UMLSCUI |
| 1143 | INN_ID |
| 3601 | PUBCHEM_CID |
| B64NJG83K2 | UNII |
Pharmaceutical products:
None