gusperimus 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| immunosuppressants | 1347 | 98629-43-7 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
synthesized by chemical modification of spergualin; in combination with cyclosporin A prevents diabetes in predisposed NOD mice; structure given in first source; RN given refers to (-)-isomer trihydrochloride
|
Drug dosage:
None
ADMET properties:
None
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | L04AA19 | ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS IMMUNOSUPPRESSANTS IMMUNOSUPPRESSANTS Selective immunosuppressants |
| MeSH PA | D000903 | Antibiotics, Antineoplastic |
| MeSH PA | D000970 | Antineoplastic Agents |
| MeSH PA | D007004 | Hypoglycemic Agents |
| MeSH PA | D007155 | Immunologic Factors |
| MeSH PA | D007166 | Immunosuppressive Agents |
| MeSH PA | D020011 | Protective Agents |
| MeSH PA | D011837 | Radiation-Protective Agents |
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
| Dissociation level | Dissociation constant | Type (acidic/basic) |
|---|---|---|
| pKa1 | 12.9 | acidic |
| pKa2 | 13.96 | acidic |
| pKa3 | 10.25 | Basic |
| pKa4 | 9.6 | Basic |
| pKa5 | 8.52 | Basic |
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D01566 | KEGG_DRUG |
| 89149-10-0 | SECONDARY_CAS_RN |
| 85468-01-5 | SECONDARY_CAS_RN |
| C0284559 | UMLSCUI |
| CHEBI:135609 | CHEBI |
| CHEMBL406117 | ChEMBL_ID |
| CHEMBL2356648 | ChEMBL_ID |
| CHEMBL1996913 | ChEMBL_ID |
| DB12692 | DRUGBANK_ID |
| C037258 | MESH_SUPPLEMENTAL_RECORD_UI |
| 55362 | PUBCHEM_CID |
| 6941 | INN_ID |
| UJ0ZJ76DO9 | UNII |
| DB12991 | DRUGBANK_ID |
Pharmaceutical products:
None