guanoxan 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
benzodioxane derivatives 1346 2165-19-7

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • guanoxan sulfate
  • guanoxan
  • guanoxane
was MH 1976-92 (see under GUANIDINES 1976-90); use GUANIDINES to search GUANOXAN 1976-92; antihypertensive agent similar in its mechanism of action to guanethidine; may cause liver damage
  • Molecular weight: 207.23
  • Formula: C10H13N3O2
  • CLOGP: 0.71
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 3
  • TPSA: 80.36
  • ALOGS: -2.19
  • ROTB: 2

Drug dosage:

DoseUnitRoute
20 mg O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC C02CC03 CARDIOVASCULAR SYSTEM
ANTIHYPERTENSIVES
ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING
Guanidine derivatives

Drug Use (View source of the data)

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 13.07 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D04399 KEGG_DRUG
5714-04-5 SECONDARY_CAS_RN
C0018320 UMLSCUI
CHEBI:134871 CHEBI
CHEMBL76725 ChEMBL_ID
DB13211 DRUGBANK_ID
CHEMBL1742462 ChEMBL_ID
16564 PUBCHEM_CID
1826 INN_ID
C073344 MESH_SUPPLEMENTAL_RECORD_UI
9V0MRL0R5Y UNII

Pharmaceutical products:

None