guanoxabenz 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
antihypertensives, guanidine derivatives 1345 24047-25-4

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • guanoxabenz
  • hydroxyguanabenz
  • guanoxabenz hydrochloride
  • Molecular weight: 247.08
  • Formula: C8H8Cl2N4O
  • CLOGP: 1.53
  • LIPINSKI: 0
  • HAC: 5
  • HDO: 4
  • TPSA: 80.50
  • ALOGS: -3.41
  • ROTB: 2

Drug dosage:

DoseUnitRoute
25 mg O

ADMET properties:

None

Approvals:

None

FDA Adverse Event Reporting System (Female)

None

FDA Adverse Event Reporting System (Male)

None

FDA Adverse Event Reporting System (Geriatric)

None

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC C02CC07 CARDIOVASCULAR SYSTEM
ANTIHYPERTENSIVES
ANTIADRENERGIC AGENTS, PERIPHERALLY ACTING
Guanidine derivatives

Drug Use (View source of the data)

None




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 7.92 acidic
pKa2 4.36 Basic
pKa3 0.0 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
D04398 KEGG_DRUG
C0061990 UMLSCUI
CHEBI:135006 CHEBI
CHEMBL461343 ChEMBL_ID
DB13410 DRUGBANK_ID
C028782 MESH_SUPPLEMENTAL_RECORD_UI
9567831 PUBCHEM_CID
3615 INN_ID
23256-40-8 SECONDARY_CAS_RN
P9HIK5V7WK UNII

Pharmaceutical products:

None