glucosamine 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | BioActivity |

Stem definitionDrug idCAS RN
1307 3416-24-8

Description:

MoleculeDescription

Molfile Inchi Smiles

Synonyms:

  • glucosamine
  • Molecular weight: 179.17
  • Formula: C6H13NO5
  • CLOGP: -2.18
  • LIPINSKI: 0
  • HAC: 6
  • HDO: 5
  • TPSA: 116.17
  • ALOGS: 0.49
  • ROTB: 1

Drug dosage:

DoseUnitRoute
1.50 g O

ADMET properties:

PropertyValueReference
BA (Bioavailability) 26 % Kim MT, Sedykh A, Chakravarti SK, Saiakhov RD, Zhu H

Approvals:

DateAgencyCompanyOrphan
None FDA

FDA Adverse Event Reporting System (Female)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Sedation complication 799.50 22.44 298 35173 13524 63440027
Creatinine renal clearance decreased 797.32 22.44 311 35160 15997 63437554
Orthostatic hypotension 710.33 22.44 364 35107 35796 63417755
Sedation 660.70 22.44 355 35116 38454 63415097
Blood calcium decreased 649.47 22.44 310 35161 26141 63427410
Cognitive disorder 638.41 22.44 394 35077 55421 63398130
Balance disorder 482.69 22.44 390 35081 84032 63369519
Depressed level of consciousness 420.22 22.44 317 35154 61761 63391790
Mobility decreased 414.24 22.44 419 35052 120740 63332811
Lip dry 272.80 22.44 145 35326 15325 63438226
Duodenal ulcer perforation 252.11 22.44 276 35195 86933 63366618
Deep vein thrombosis postoperative 245.09 22.44 122 35349 11247 63442304
Folliculitis 219.81 22.44 232 35239 70085 63383466
Peripheral venous disease 215.06 22.44 124 35347 15353 63438198
Facet joint syndrome 214.65 22.44 114 35357 12024 63441527
Constipation 212.45 22.44 419 35052 224524 63229027
Therapy non-responder 206.90 22.44 233 35238 75668 63377883
Helicobacter infection 206.88 22.44 257 35214 92528 63361023
Autoimmune disorder 203.08 22.44 124 35347 17053 63436498
Muscle injury 197.86 22.44 212 35259 65133 63388418
Irritable bowel syndrome 165.88 22.44 217 35254 82195 63371356
Pericarditis 151.42 22.44 267 35204 131312 63322239
C-reactive protein abnormal 145.61 22.44 153 35318 45943 63407608
Night sweats 143.57 22.44 156 35315 48658 63404893
Joint range of motion decreased 138.59 22.44 127 35344 32301 63421250
Bursitis 137.18 22.44 134 35337 36907 63416644
Obesity 135.27 22.44 121 35350 29831 63423720
Impaired healing 133.68 22.44 220 35251 102322 63351229
Blood cholesterol increased 131.10 22.44 208 35263 93824 63359727
Prescribed overdose 129.19 22.44 125 35346 34028 63419523
Fibromyalgia 123.45 22.44 186 35285 80234 63373317
Liver injury 122.73 22.44 160 35311 60360 63393191
Hypotension 122.32 22.44 382 35089 272222 63181329
Injury 121.93 22.44 176 35295 73071 63380480
Lower limb fracture 121.74 22.44 104 35367 24117 63429434
Dry mouth 119.39 22.44 180 35291 77683 63375868
Sleep disorder due to general medical condition, insomnia type 112.08 22.44 142 35329 52075 63401476
Fall 108.59 22.44 470 35001 391864 63061687
Blister 106.02 22.44 228 35243 129586 63323965
Lower respiratory tract infection 105.34 22.44 230 35241 132077 63321474
Gait inability 104.26 22.44 138 35333 52821 63400730
Discomfort 103.92 22.44 264 35207 167110 63286441
Anti-cyclic citrullinated peptide antibody positive 102.91 22.44 211 35260 116001 63337550
Hand deformity 102.65 22.44 255 35216 159202 63294349
Lung disorder 101.27 22.44 148 35323 62113 63391438
Urticaria 100.33 22.44 259 35212 165543 63288008
Wound 99.78 22.44 256 35215 163007 63290544
Psoriatic arthropathy 96.65 22.44 179 35292 91341 63362210
Rheumatoid factor positive 95.36 22.44 170 35301 84236 63369315
Road traffic accident 93.89 22.44 109 35362 36523 63417028
Rheumatic fever 93.72 22.44 118 35353 42993 63410558
C-reactive protein 92.41 22.44 48 35423 4834 63448717
Stomatitis 91.54 22.44 224 35247 138501 63315050
Osteoarthritis 90.24 22.44 178 35293 95165 63358386
Death 87.97 22.44 50 35421 374331 63079220
Swollen joint count increased 85.32 22.44 103 35368 35951 63417600
Toxicity to various agents 84.91 22.44 317 35154 246933 63206618
Acute kidney injury 83.58 22.44 22 35449 263393 63190158
Glossodynia 83.20 22.44 254 35217 178622 63274929
Pemphigus 82.78 22.44 258 35213 183468 63270083
Hepatic enzyme increased 71.59 22.44 262 35209 202066 63251485
Hip arthroplasty 71.37 22.44 109 35362 47537 63406014
Synovitis 71.22 22.44 248 35223 186670 63266881
Anaemia 70.61 22.44 38 35433 293392 63160159
X-ray abnormal 69.85 22.44 48 35423 8062 63445489
Ill-defined disorder 69.48 22.44 146 35325 81609 63371942
Adjustment disorder with depressed mood 68.68 22.44 52 35419 10152 63443399
Gastrointestinal disorder 66.35 22.44 192 35279 131047 63322504
Systemic lupus erythematosus 66.05 22.44 261 35210 208657 63244894
Oedema 65.82 22.44 159 35312 97463 63356088
Musculoskeletal pain 64.05 22.44 152 35319 92125 63361426
Type 2 diabetes mellitus 61.32 22.44 120 35351 63748 63389803
Intentional product use issue 60.73 22.44 183 35288 127709 63325842
Contusion 58.80 22.44 201 35270 149843 63303708
Wheezing 58.44 22.44 150 35321 95445 63358106
Treatment failure 56.06 22.44 240 35231 198803 63254748
Sepsis 54.17 22.44 10 35461 153113 63300438
Inflammation 52.27 22.44 131 35340 82142 63371409
Lupus vulgaris 50.50 22.44 35 35436 5959 63447592
Nausea 50.19 22.44 277 35194 854194 62599357
Multiple drug therapy 50.07 22.44 29 35442 3617 63449934
Rheumatoid arthritis 49.86 22.44 276 35195 253543 63200008
Neutropenia 49.40 22.44 18 35453 174987 63278564
Arthropathy 49.29 22.44 260 35211 234532 63219019
Liver disorder 49.28 22.44 99 35372 53588 63399963
Musculoskeletal stiffness 49.23 22.44 219 35252 184399 63269152
Seizure 48.36 22.44 8 35463 132626 63320925
Knee arthroplasty 47.43 22.44 98 35373 54108 63399443
Pain 47.18 22.44 625 34846 740003 62713548
Nasopharyngitis 46.99 22.44 272 35199 253985 63199566
Grip strength decreased 46.83 22.44 60 35411 22227 63431324
Sciatica 46.51 22.44 75 35396 34249 63419302
Swelling 46.05 22.44 287 35184 275091 63178460
Confusional state 44.40 22.44 254 35217 236126 63217425
Febrile neutropenia 43.50 22.44 7 35464 118442 63335109
Somnolence 43.15 22.44 23 35448 178662 63274889
Drug ineffective 42.96 22.44 376 35095 1044389 62409162
Infusion related reaction 41.73 22.44 257 35214 245264 63208287
Hypokalaemia 40.78 22.44 5 35466 103799 63349752
Cardiac arrest 40.20 22.44 3 35468 92542 63361009
General physical health deterioration 39.52 22.44 219 35252 201183 63252368
Dislocation of vertebra 39.20 22.44 35 35436 8600 63444951
Erythema 39.07 22.44 25 35446 175726 63277825
Renal failure 38.88 22.44 9 35462 117643 63335908
Syncope 38.75 22.44 9 35462 117376 63336175
Peripheral swelling 38.27 22.44 267 35204 265675 63187876
Chest pain 37.92 22.44 228 35243 215731 63237820
Wound infection 37.88 22.44 53 35418 21357 63432194
Therapeutic product effect decreased 37.86 22.44 210 35261 192977 63260574
Pulmonary embolism 36.49 22.44 10 35461 116674 63336877
Maternal exposure during pregnancy 35.91 22.44 228 35243 219834 63233717
Tachycardia 35.34 22.44 11 35460 118145 63335406
Respiratory failure 35.27 22.44 7 35464 101851 63351700
Pregnancy 35.09 22.44 69 35402 36767 63416784
Malignant neoplasm progression 34.72 22.44 3 35468 82118 63371433
Thrombocytopenia 34.28 22.44 21 35450 151136 63302415
Eye injury 34.17 22.44 21 35450 2918 63450633
Prescribed underdose 33.76 22.44 60 35411 29629 63423922
Cough 33.43 22.44 71 35400 292672 63160879
Abdominal discomfort 33.42 22.44 299 35172 320586 63132965
Alopecia 32.88 22.44 310 35161 337226 63116325
Pneumonia 31.94 22.44 139 35332 456628 62996923
Loss of consciousness 31.91 22.44 13 35458 118108 63335443
Breast cancer stage II 31.20 22.44 31 35440 8705 63444846
Contraindicated product administered 30.99 22.44 218 35253 217430 63236121
Urinary tract infection 30.38 22.44 64 35407 264620 63188931
Drug interaction 30.16 22.44 51 35420 229080 63224471
Weight increased 29.75 22.44 248 35223 260544 63193007
Product use issue 29.73 22.44 218 35253 220302 63233249
Aspartate aminotransferase increased 29.64 22.44 7 35464 90270 63363281
Muscle spasms 29.42 22.44 168 35303 155982 63297569
Dysphagia 28.83 22.44 7 35464 88578 63364973
Alanine aminotransferase increased 28.72 22.44 11 35460 103759 63349792
Renal impairment 28.72 22.44 7 35464 88348 63365203
Asthma 28.63 22.44 144 35327 127417 63326134
Medication error 27.85 22.44 78 35393 52206 63401345
Dehydration 27.32 22.44 34 35437 173320 63280231
Cardiac failure 27.20 22.44 8 35463 89134 63364417
Oxygen saturation decreased 26.94 22.44 8 35463 88577 63364974
Maternal exposure timing unspecified 26.90 22.44 26 35445 7061 63446490
Septic shock 26.69 22.44 3 35468 66626 63386925
Deep vein thrombosis 26.54 22.44 7 35464 83793 63369758
Hyponatraemia 26.14 22.44 15 35456 111885 63341666
Abdominal pain upper 26.08 22.44 201 35270 206243 63247308
Product use in unapproved indication 25.85 22.44 180 35291 178900 63274651
Hyperhidrosis 25.85 22.44 14 35457 107822 63345729
Product dose omission issue 25.77 22.44 58 35413 234255 63219296
Headache 25.40 22.44 229 35242 633012 62820539
Myocardial infarction 25.39 22.44 12 35459 99881 63353670
Tremor 25.27 22.44 22 35449 132217 63321334
Blood creatinine increased 24.84 22.44 9 35462 87835 63365716
Chest discomfort 23.94 22.44 16 35455 109953 63343598
Perseveration 23.78 22.44 8 35463 267 63453284
Therapeutic product effect incomplete 23.66 22.44 21 35450 125035 63328516
Adverse event 23.43 22.44 87 35384 67472 63386079
Bradycardia 23.41 22.44 6 35465 73221 63380330
Back pain 23.27 22.44 73 35398 264072 63189479
Injection site pain 23.14 22.44 23 35448 129777 63323774
Infection 23.04 22.44 212 35259 228961 63224590
Chills 22.73 22.44 18 35453 113360 63340191
Ulcer haemorrhage 22.69 22.44 21 35450 5401 63448150
Pancytopenia 22.63 22.44 13 35458 96920 63356631
Platelet count decreased 22.57 22.44 19 35452 116103 63337448

FDA Adverse Event Reporting System (Male)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Milk-alkali syndrome 97.51 19.75 21 4302 584 34952024
Metabolic alkalosis 42.44 19.75 13 4310 1488 34951120
Hypercalcaemia 33.69 19.75 22 4301 15446 34937162
Fatigue 33.51 19.75 111 4212 370542 34582066
Psoriasis 26.24 19.75 28 4295 38784 34913824
HLA marker study positive 24.64 19.75 5 4318 103 34952505
Flatulence 23.30 19.75 20 4303 21178 34931430
Diarrhoea 20.74 19.75 99 4224 389813 34562795
Myalgia 20.44 19.75 37 4286 84073 34868535
Decubitus ulcer 20.19 19.75 13 4310 8908 34943700
Product dose omission issue 19.94 19.75 45 4278 119666 34832942

FDA Adverse Event Reporting System (Geriatric)

MedDRA adverse event termLikelihood ratioLikelihood ratio thresholdPatients taking drug having adverse eventPatients taking drug not having adverse eventPatients not taking drug having adverse eventPatients not taking drug not having adverse event
Sedation complication 855.10 22.70 303 34352 15366 79694367
Creatinine renal clearance decreased 841.67 22.70 315 34340 18687 79691046
Blood calcium decreased 691.07 22.70 317 34338 31502 79678231
Orthostatic hypotension 653.85 22.70 367 34288 55797 79653936
Cognitive disorder 650.42 22.70 395 34260 69531 79640202
Sedation 644.87 22.70 354 34301 51541 79658192
Balance disorder 510.56 22.70 388 34267 98469 79611264
Mobility decreased 476.87 22.70 407 34248 121768 79587965
Depressed level of consciousness 372.91 22.70 320 34335 96332 79613401
Lip dry 295.53 22.70 141 34514 15277 79694456
Duodenal ulcer perforation 271.21 22.70 227 34428 65984 79643749
Folliculitis 269.48 22.70 210 34445 55170 79654563
Deep vein thrombosis postoperative 255.02 22.70 114 34541 10638 79699095
Constipation 250.42 22.70 444 34211 282606 79427127
Muscle injury 246.86 22.70 189 34466 48372 79661361
Facet joint syndrome 243.29 22.70 112 34543 11190 79698543
Peripheral venous disease 229.58 22.70 120 34535 15789 79693944
Helicobacter infection 223.50 22.70 208 34447 69496 79640237
Irritable bowel syndrome 215.68 22.70 194 34461 62047 79647686
Autoimmune disorder 210.73 22.70 115 34540 16497 79693236
Night sweats 175.79 22.70 160 34495 51935 79657798
Pericarditis 173.42 22.70 220 34435 104016 79605717
C-reactive protein abnormal 168.01 22.70 151 34504 48216 79661517
Pemphigus 163.79 22.70 209 34446 99373 79610360
Impaired healing 161.88 22.70 195 34460 87460 79622273
Bursitis 161.59 22.70 130 34525 35714 79674019
Joint range of motion decreased 157.07 22.70 124 34531 33158 79676575
Fibromyalgia 156.13 22.70 165 34490 64175 79645558
Anti-cyclic citrullinated peptide antibody positive 155.23 22.70 186 34469 82957 79626776
Blood cholesterol increased 154.19 22.70 186 34469 83534 79626199
Hand deformity 153.70 22.70 207 34448 103712 79606021
Glossodynia 153.08 22.70 206 34449 103131 79606602
Sleep disorder due to general medical condition, insomnia type 145.43 22.70 133 34522 43423 79666310
Obesity 140.80 22.70 119 34536 35006 79674727
Liver injury 140.59 22.70 147 34508 56467 79653266
Discomfort 138.83 22.70 218 34437 125399 79584334
Wound 137.33 22.70 208 34447 115971 79593762
Lower respiratory tract infection 135.59 22.70 219 34436 129001 79580732
Therapy non-responder 135.16 22.70 183 34472 92122 79617611
Systemic lupus erythematosus 134.93 22.70 211 34444 120938 79588795
Dry mouth 134.23 22.70 178 34477 87841 79621892
Lower limb fracture 132.74 22.70 97 34558 23118 79686615
Osteoarthritis 132.28 22.70 176 34479 87133 79622600
Rheumatoid factor positive 132.11 22.70 146 34509 59693 79650040
Blister 126.04 22.70 203 34452 119273 79590460
Stomatitis 122.81 22.70 225 34430 146532 79563201
Fall 120.50 22.70 474 34181 487155 79222578
Gait inability 120.25 22.70 138 34517 58779 79650954
Injury 118.58 22.70 157 34498 77339 79632394
Rheumatic fever 117.12 22.70 98 34557 28427 79681306
Psoriatic arthropathy 116.25 22.70 156 34499 77843 79631890
Prescribed overdose 107.99 22.70 106 34549 37777 79671956
Swollen joint count increased 102.99 22.70 83 34572 22844 79686889
C-reactive protein 102.96 22.70 48 34607 4931 79704802
Arthropathy 102.40 22.70 233 34422 176878 79532855
Pain 100.71 22.70 584 34071 703218 79006515
Lung disorder 94.83 22.70 144 34511 80413 79629320
Road traffic accident 93.72 22.70 105 34550 43559 79666174
Ill-defined disorder 92.47 22.70 128 34527 65747 79643986
Hip arthroplasty 90.82 22.70 94 34561 35662 79674071
Synovitis 90.13 22.70 201 34454 150533 79559200
Alopecia 86.99 22.70 259 34396 231096 79478637
Gastrointestinal disorder 85.81 22.70 174 34481 122031 79587702
Hypotension 85.44 22.70 398 34257 439919 79269814
Urticaria 84.02 22.70 222 34433 184979 79524754
Hepatic enzyme increased 80.92 22.70 217 34438 182393 79527340
Adjustment disorder with depressed mood 80.91 22.70 50 34605 9036 79700697
Maternal exposure during pregnancy 80.42 22.70 181 34474 136357 79573376
X-ray abnormal 78.61 22.70 42 34613 5771 79703962
Musculoskeletal pain 75.76 22.70 149 34506 102205 79607528
Swelling 75.27 22.70 236 34419 216475 79493258
Rheumatoid arthritis 74.23 22.70 229 34426 208241 79501492
Acute kidney injury 74.12 22.70 70 34585 519334 79190399
Contusion 70.18 22.70 181 34474 148595 79561138
Therapeutic product effect decreased 69.86 22.70 192 34463 163671 79546062
Treatment failure 68.98 22.70 196 34459 170290 79539443
Musculoskeletal stiffness 68.68 22.70 199 34456 174809 79534924
Death 68.02 22.70 88 34567 566426 79143307
Abdominal discomfort 66.87 22.70 250 34405 250477 79459256
Febrile neutropenia 65.18 22.70 11 34644 230988 79478745
Peripheral swelling 63.11 22.70 258 34397 269359 79440374
Contraindicated product administered 61.68 22.70 179 34476 157359 79552374
Type 2 diabetes mellitus 60.10 22.70 97 34558 57025 79652708
Nasopharyngitis 59.45 22.70 243 34412 253638 79456095
Pregnancy 58.35 22.70 65 34590 26786 79682947
Inflammation 58.24 22.70 127 34528 93626 79616107
Neutropenia 56.79 22.70 27 34628 287683 79422050
Sciatica 56.58 22.70 71 34584 33151 79676582
Grip strength decreased 56.45 22.70 58 34597 21811 79687922
Cardiac arrest 56.33 22.70 5 34650 172091 79537642
Wheezing 56.10 22.70 143 34512 116521 79593212
Intentional product use issue 55.89 22.70 169 34486 151943 79557790
Sepsis 55.18 22.70 24 34631 269404 79440329
Knee arthroplasty 54.73 22.70 80 34575 43168 79666565
Multiple drug therapy 53.84 22.70 29 34626 4049 79705684
Milk-alkali syndrome 53.70 22.70 21 34634 1399 79708334
Renal failure 53.63 22.70 11 34644 200957 79508776
Oedema 51.82 22.70 141 34514 119439 79590294
Infusion related reaction 48.94 22.70 214 34441 230023 79479710
Anaemia 48.51 22.70 74 34581 444941 79264792
Dislocation of vertebra 45.20 22.70 33 34622 7847 79701886
Tachycardia 44.88 22.70 11 34644 177757 79531976
Muscle spasms 44.70 22.70 172 34483 174558 79535175
Respiratory failure 44.13 22.70 12 34643 180899 79528834
Weight increased 43.29 22.70 236 34419 277150 79432583
Asthma 43.12 22.70 143 34512 134952 79574781
Pneumonia 42.58 22.70 146 34509 660100 79049633
Drug intolerance 42.08 22.70 226 34429 263893 79445840
Wound infection 42.01 22.70 52 34603 23939 79685794
Somnolence 41.94 22.70 26 34629 238955 79470778
Erythema 41.01 22.70 23 34632 223267 79486466
Drug interaction 39.75 22.70 75 34580 415108 79294625
Toxicity to various agents 39.73 22.70 316 34339 421224 79288509
Renal impairment 39.37 22.70 10 34645 157773 79551960
Alanine aminotransferase increased 39.24 22.70 11 34644 162559 79547174
Lupus vulgaris 39.23 22.70 22 34633 3324 79706409
Hyperkalaemia 38.32 22.70 3 34652 114395 79595338
Syncope 38.32 22.70 15 34640 179434 79530299
Cardiac failure 38.27 22.70 10 34645 154832 79554901
Breast cancer stage II 37.75 22.70 30 34625 8090 79701643
Interstitial lung disease 37.59 22.70 3 34652 112597 79597136
Thrombocytopenia 37.47 22.70 36 34619 265223 79444510
Drug abuse 37.47 22.70 12 34643 162679 79547054
Maternal exposure timing unspecified 37.24 22.70 26 34629 5766 79703967
Aspartate aminotransferase increased 36.14 22.70 8 34647 138633 79571100
Product use issue 35.79 22.70 183 34472 209639 79500094
Abdominal pain upper 35.28 22.70 191 34464 223628 79486105
Confusional state 34.22 22.70 246 34409 317751 79391982
Liver disorder 34.01 22.70 88 34567 72329 79637404
Joint swelling 33.83 22.70 228 34427 288418 79421315
Pancytopenia 33.54 22.70 15 34640 165730 79544003
Multiple organ dysfunction syndrome 33.30 22.70 6 34649 120240 79589493
Hypoglycaemia 33.11 22.70 3 34652 101591 79608142
Bradycardia 33.04 22.70 9 34646 135548 79574185
Infection 32.68 22.70 198 34457 241514 79468219
Oxygen saturation decreased 30.65 22.70 9 34646 129038 79580695
Nausea 29.59 22.70 270 34385 956926 78752807
Adverse drug reaction 29.46 22.70 79 34576 66313 79643420
Live birth 28.68 22.70 38 34617 18706 79691027
Seizure 28.61 22.70 24 34631 188810 79520923
Septic shock 28.38 22.70 9 34646 122792 79586941
Adverse event 28.09 22.70 73 34582 60141 79649592
Hypokalaemia 27.66 22.70 14 34641 144026 79565707
Myocardial infarction 27.16 22.70 24 34631 184105 79525628
Loss of consciousness 27.13 22.70 20 34635 167923 79541810
Medication error 26.84 22.70 78 34577 68564 79641169
Paraesthesia 26.79 22.70 149 34506 176174 79533559
Dysphagia 26.41 22.70 10 34645 122126 79587607
Leukopenia 26.11 22.70 9 34646 116504 79593229
Haemoglobin decreased 26.08 22.70 35 34620 222084 79487649
Sleep disorder 25.83 22.70 89 34566 85588 79624145
Platelet count decreased 25.68 22.70 28 34627 194636 79515097
Prescribed underdose 25.59 22.70 46 34609 29468 79680265
Agitation 25.49 22.70 6 34649 99709 79610024
Hypersensitivity 25.44 22.70 198 34457 262041 79447692
Metabolic acidosis 25.44 22.70 3 34652 82526 79627207
Drug ineffective 25.33 22.70 325 34330 1080588 78629145
Tremor 25.29 22.70 22 34633 170061 79539672
Sinusitis 25.06 22.70 158 34497 195343 79514390
Chest pain 24.60 22.70 208 34447 282096 79427637
Pulmonary embolism 24.57 22.70 23 34632 171631 79538102
Hallucination 24.35 22.70 4 34651 85741 79623992
Breast cancer stage III 23.46 22.70 25 34630 9801 79699932
Blood creatinine increased 23.12 22.70 20 34635 155037 79554696
Cough 22.98 22.70 82 34573 366707 79343026
Perseveration 22.87 22.70 8 34647 389 79709344

FDA Adverse Event Reporting System (Pediatric)

None

Pharmacologic Action:

SourceCodeDescription
ATC M01AX05 MUSCULO-SKELETAL SYSTEM
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
Other antiinflammatory and antirheumatic agents, non-steroids

Drug Use | Suggest Off label Use Form| |View source of the data|

DiseaseRelationSNOMED_IDDOID
Hyperphosphatemia contraindication 20165001 DOID:0050459
Hypervitaminosis D contraindication 27712000 DOID:9971
Sarcoidosis contraindication 31541009 DOID:11335
Hypertensive disorder contraindication 38341003 DOID:10763
Hyperlipidemia contraindication 55822004 DOID:1168
Hypercalcemia contraindication 66931009 DOID:12678
Diabetes mellitus contraindication 73211009 DOID:9351
Kidney disease contraindication 90708001 DOID:557
Kidney stone contraindication 95570007
Arteriosclerosis obliterans contraindication 361133006 DOID:5160




🐶 Veterinary Drug Use

None

🐶 Veterinary products

None

Acid dissociation constants calculated using MoKa v3.0.0

Dissociation levelDissociation constantType (acidic/basic)
pKa1 11.28 acidic
pKa2 12.49 acidic
pKa3 14.0 acidic
pKa4 7.29 Basic

Orange Book patent data (new drug applications)

None

Orange Book exclusivity data (new drug applications)

None

Bioactivity Summary:

None

External reference:

IDSource
4021359 VUID
N0000148778 NUI
D04334 KEGG_DRUG
4021359 VANDF
C0017718 UMLSCUI
CHEBI:5417 CHEBI
CHEMBL493287 ChEMBL_ID
CHEMBL606759 ChEMBL_ID
DB01296 DRUGBANK_ID
D005944 MESH_DESCRIPTOR_UI
439213 PUBCHEM_CID
3120 INN_ID
N08U5BOQ1K UNII
4845 RXNORM
19221 MMSL
d04418 MMSL
004563 NDDF
408111007 SNOMEDCT_US
70237008 SNOMEDCT_US

Pharmaceutical products:

ProductCategoryIngredientsNDCFormQuantityRouteMarketingLabel
Remaxazon External Patch HUMAN PRESCRIPTION DRUG LABEL 4 69379-285 PATCH 5 g TOPICAL unapproved drug other 2 sections