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gemeprost 🐶 Veterinary Use | Indications/Contra | FAERs-F | FAERs-M | Orange Bk | PK/Tox | Related Drugs | BioActivity |
| Stem definition | Drug id | CAS RN |
|---|---|---|
| prostaglandins | 1284 | 64318-79-2 |
Description:
| Molecule | Description |
|---|---|
|
Synonyms:
|
used for preoperative dilation of cervix before surgical abortion; RN given refers to (2E,11alpha,13E,15R)-isomer
|
Drug dosage:
| Dose | Unit | Route |
|---|---|---|
| 1 | mg | V |
ADMET properties:
None
Predicted pharmacokinetic/toxicological properties (PK-AZ):
| Property | Description | Value | Unit | Confidence | Similarity |
|---|---|---|---|---|---|
| kinase-safety-class | ACVR2A,ACVR2B,ACVRL1,AKT2,AURKA,AXL,BRAF,BTK,CAMK2B,CAMK2D,CDK4,CDK5,CDK9,DDR1,DYRK1B,EGFR,EIF2AK3,EPHB4,ERBB2,FLT3,GRK2,GSK3B,IGF1R,IKBKB,ITK,JAK2,JAK3,KDR,MAP2K6,MAP3K21,MAP3K7,MAPK10,MAPK7,MAPK9,MAPKAPK2,MTOR,NTRK2,PDK1,PDK2,PDK4,PDPK1,PIK3CB,PIK3CG,PIM2,PLK1,PLK2,PLK3,PRKDC,SIK2,SIK3,STK33,SYK,TEK,TGFBR1,TTK,ZAP70 | 56 | |||
| kinase-selectivity-class | AXL,GRK2 | 2 | |||
| pfas-class | PFAS structural alert (1 = True, 0 = False) | 0 |
Approvals:
None
FDA Adverse Event Reporting System (Female)
None
FDA Adverse Event Reporting System (Male)
None
FDA Adverse Event Reporting System (Geriatric)
None
FDA Adverse Event Reporting System (Pediatric)
None
Pharmacologic Action:
| Source | Code | Description |
|---|---|---|
| ATC | G02AD03 | GENITO URINARY SYSTEM AND SEX HORMONES OTHER GYNECOLOGICALS UTEROTONICS Prostaglandins |
| MeSH PA | D000019 | Abortifacient Agents |
| MeSH PA | D000020 | Abortifacient Agents, Nonsteroidal |
| MeSH PA | D012102 | Reproductive Control Agents |
Related Drugs by ATC class:
G02AD Prostaglandins 5 drugs
Drug Use | Suggest Off label Use Form| |View source of the data|
None
🐶 Veterinary Drug Use
None
🐶 Veterinary products
None
Acid dissociation constants calculated using MoKa v3.0.0
None
Orange Book patent data (new drug applications)
None
Orange Book exclusivity data (new drug applications)
None
Bioactivity Summary:
None
External reference:
| ID | Source |
|---|---|
| D02073 | KEGG_DRUG |
| C0044923 | UMLSCUI |
| CHEBI:135626 | CHEBI |
| CHEMBL1908315 | ChEMBL_ID |
| DB08964 | DRUGBANK_ID |
| C021182 | MESH_SUPPLEMENTAL_RECORD_UI |
| 5282237 | PUBCHEM_CID |
| 4738 | INN_ID |
| 45KZB1FOLS | UNII |
| 12449 | RXNORM |
| 003970 | NDDF |
| 326128005 | SNOMEDCT_US |
| 395729005 | SNOMEDCT_US |
Pharmaceutical products:
None